Megan Mayerle, PhD
|The Johns Hopkins University||PhD||2012||Biology|
|Marquette University||BS||2004||Biology and English Literature|
|University of California San Francisco||2016
||2016||RNA Society Travel Award|
|Johns Hopkins University||2009
||2010||Deans Teaching Fellowship|
|Marquette University||2004||Alpha Sigma Nu Membership|
|Johns Hopkins University||2010
||2010||Graduate Representative Organization Travel Grant|
Cells have developed elaborate mechanisms to minimize errors in gene expression. These fall into two broad categories: 1) fidelity mechanisms intrinsic to the gene expression machinery that minimize errors during transcription, RNA pro-cessing, and translation, and 2) surveillance mechanisms that scan the products of the gene expression machinery for errors and correct them. I am broadly interested the mechanistic basis of how the components of the large, RNA-protein complexes involved in gene expression maintain fidelity, and how aberrant versions of these complexes can cause and contribute to human diseases.
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