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Megan Riel-Mehan, PhD

TitlePostdoctoral Scholar
SchoolUCSF School of Pharmacy
DepartmentBioengineering
Address600 16th St
San Francisco CA 94158
Phone415-476-5379
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPh.D.2013 Graduate Division (Chemistry and Chemical Biology)

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Nersisyan L, Johnson G, Riel-Mehan M, Pico A, Arakelyan A. PSFC: a Pathway Signal Flow Calculator App for Cytoscape. F1000Res. 2015; 4:480. PMID: 26834984.
      View in: PubMed
    2. Riel-Mehan MM, Shokat KM. A crosslinker based on a tethered electrophile for mapping kinase-substrate networks. Chem Biol. 2014 May 22; 21(5):585-90. PMID: 24746561; PMCID: PMC4627693.
    3. Barile E, De SK, Carlson CB, Chen V, Knutzen C, Riel-Mehan M, Yang L, Dahl R, Chiang G, Pellecchia M. Design, synthesis, and structure-activity relationships of 3-ethynyl-1H-indazoles as inhibitors of the phosphatidylinositol 3-kinase signaling pathway. J Med Chem. 2010 Dec 9; 53(23):8368-75. PMID: 21062009.
      View in: PubMed
    4. De SK, Chen V, Stebbins JL, Chen LH, Cellitti JF, Machleidt T, Barile E, Riel-Mehan M, Dahl R, Yang L, Emdadi A, Murphy R, Pellecchia M. Synthesis and optimization of thiadiazole derivatives as a novel class of substrate competitive c-Jun N-terminal kinase inhibitors. Bioorg Med Chem. 2010 Jan 15; 18(2):590-6. PMID: 20045647; PMCID: PMC2818674.
    5. De SK, Stebbins JL, Chen LH, Riel-Mehan M, Machleidt T, Dahl R, Yuan H, Emdadi A, Barile E, Chen V, Murphy R, Pellecchia M. Design, synthesis, and structure-activity relationship of substrate competitive, selective, and in vivo active triazole and thiadiazole inhibitors of the c-Jun N-terminal kinase. J Med Chem. 2009 Apr 9; 52(7):1943-52. PMID: 19271755; PMCID: PMC2667321.
    6. De SK, Chen LH, Stebbins JL, Machleidt T, Riel-Mehan M, Dahl R, Chen V, Yuan H, Barile E, Emdadi A, Murphy R, Pellecchia M. Discovery of 2-(5-nitrothiazol-2-ylthio)benzo[d]thiazoles as novel c-Jun N-terminal kinase inhibitors. Bioorg Med Chem. 2009 Apr 1; 17(7):2712-7. PMID: 19282190; PMCID: PMC2828351.
    7. Gaitonde S, De SK, Tcherpakov M, Dewing A, Yuan H, Riel-Mehan M, Krajewski S, Robertson G, Pellecchia M, Ronai Z. BI-69A11-mediated inhibition of AKT leads to effective regression of xenograft melanoma. Pigment Cell Melanoma Res. 2009 Apr; 22(2):187-95. PMID: 19175524; PMCID: PMC2860277.
    8. Stebbins JL, De SK, Machleidt T, Becattini B, Vazquez J, Kuntzen C, Chen LH, Cellitti JF, Riel-Mehan M, Emdadi A, Solinas G, Karin M, Pellecchia M. Identification of a new JNK inhibitor targeting the JNK-JIP interaction site. Proc Natl Acad Sci U S A. 2008 Oct 28; 105(43):16809-13. PMID: 18922779; PMCID: PMC2567907.
    9. Vazquez J, De SK, Chen LH, Riel-Mehan M, Emdadi A, Cellitti J, Stebbins JL, Rega MF, Pellecchia M. Development of paramagnetic probes for molecular recognition studies in protein kinases. J Med Chem. 2008 Jun 26; 51(12):3460-5. PMID: 18494454; PMCID: PMC2825083.
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