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    Michael Pickup, PhD

    TitlePostdoctoral Scholar
    SchoolUCSF School of Medicine
    DepartmentSurgery
    Address513 Parnassus Avenue
    San Francisco CA 94117
    Phone415-476-3973
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      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Miroshnikova YA, Mouw JK, Barnes JM, Pickup MW, Lakins JN, Kim Y, Lobo K, Persson AI, Reis GF, McKnight TR, Holland EC, Phillips JJ, Weaver VM. Tissue mechanics promote IDH1-dependent HIF1a-tenascin C feedback to regulate glioblastoma aggression. Nat Cell Biol. 2016 Nov 07. PMID: 27820599.
        View in: PubMed
      2. Jovanovic B, Pickup MW, Chytil A, Gorska AE, Johnson KC, Moses HL, Owens P. TßRIII Expression in Human Breast Cancer Stroma and the Role of Soluble TßRIII in Breast Cancer Associated Fibroblasts. Cancers (Basel). 2016 Nov 04; 8(11). PMID: 27827906.
        View in: PubMed
      3. Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, Kalluri R, Iacobuzio-Donahue CA, Wood LD, Hebrok M, Hansen K, Moses HL, Weaver VM. Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nat Med. 2016 May; 22(5):497-505. PMID: 27089513.
        View in: PubMed
      4. Pickup MW, Hover LD, Guo Y, Gorska AE, Chytil A, Novitskiy SV, Moses HL, Owens P. Deletion of the BMP receptor BMPR1a impairs mammary tumor formation and metastasis. Oncotarget. 2015 Sep 8; 6(26):22890-904. PMID: 26274893.
        View in: PubMed
      5. Shaw AK, Pickup MW, Chytil A, Aakre M, Owens P, Moses HL, Novitskiy SV. TGFß signaling in myeloid cells regulates mammary carcinoma cell invasion through fibroblast interactions. PLoS One. 2015; 10(1):e0117908. PMID: 25629162; PMCID: PMC4309578.
      6. Bates AL, Pickup MW, Hallett MA, Dozier EA, Thomas S, Fingleton B. Stromal matrix metalloproteinase 2 regulates collagen expression and promotes the outgrowth of experimental metastases. J Pathol. 2015 Apr; 235(5):773-83. PMID: 25469981; PMCID: PMC4357558 [Available on 04/01/16].
      7. Pickup MW, Mouw JK, Weaver VM. The extracellular matrix modulates the hallmarks of cancer. EMBO Rep. 2014 Dec; 15(12):1243-53. PMID: 25381661; PMCID: PMC4264927.
      8. Novitskiy SV, Forrester E, Pickup MW, Gorska AE, Chytil A, Aakre M, Polosukhina D, Owens P, Yusupova DR, Zhao Z, Ye F, Shyr Y, Moses HL. Attenuated transforming growth factor beta signaling promotes metastasis in a model of HER2 mammary carcinogenesis. Breast Cancer Res. 2014; 16(5):425. PMID: 25280532; PMCID: PMC4303109.
      9. Pickup MW, Hover LD, Polikowsky ER, Chytil A, Gorska AE, Novitskiy SV, Moses HL, Owens P. BMPR2 loss in fibroblasts promotes mammary carcinoma metastasis via increased inflammation. Mol Oncol. 2015 Jan; 9(1):179-91. PMID: 25205038; PMCID: PMC4277920 [Available on 01/01/16].
      10. Ryzhov SV, Pickup MW, Chytil A, Gorska AE, Zhang Q, Owens P, Feoktistov I, Moses HL, Novitskiy SV. Role of TGF-ß signaling in generation of CD39+CD73+ myeloid cells in tumors. J Immunol. 2014 Sep 15; 193(6):3155-64. PMID: 25127858; PMCID: PMC4157098.
      11. Jovanovic B, Beeler JS, Pickup MW, Chytil A, Gorska AE, Ashby WJ, Lehmann BD, Zijlstra A, Pietenpol JA, Moses HL. Transforming growth factor beta receptor type III is a tumor promoter in mesenchymal-stem like triple negative breast cancer. Breast Cancer Res. 2014; 16(4):R69. PMID: 24985072; PMCID: PMC4095685.
      12. Hansen AG, Arnold SA, Jiang M, Palmer TD, Ketova T, Merkel A, Pickup M, Samaras S, Shyr Y, Moses HL, Hayward SW, Sterling JA, Zijlstra A. ALCAM/CD166 is a TGF-ß-responsive marker and functional regulator of prostate cancer metastasis to bone. Cancer Res. 2014 Mar 1; 74(5):1404-15. PMID: 24385212; PMCID: PMC4149913.
      13. Pickup M, Novitskiy S, Moses HL. The roles of TGFß in the tumour microenvironment. Nat Rev Cancer. 2013 Nov; 13(11):788-99. PMID: 24132110; PMCID: PMC4025940.
      14. Pickup MW, Laklai H, Acerbi I, Owens P, Gorska AE, Chytil A, Aakre M, Weaver VM, Moses HL. Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-ß-deficient mouse mammary carcinomas. Cancer Res. 2013 Sep 1; 73(17):5336-46. PMID: 23856251; PMCID: PMC3766496.
      15. Owens P, Polikowsky H, Pickup MW, Gorska AE, Jovanovic B, Shaw AK, Novitskiy SV, Hong CC, Moses HL. Bone Morphogenetic Proteins stimulate mammary fibroblasts to promote mammary carcinoma cell invasion. PLoS One. 2013; 8(6):e67533. PMID: 23840733; PMCID: PMC3695869.
      16. Matise LA, Palmer TD, Ashby WJ, Nashabi A, Chytil A, Aakre M, Pickup MW, Gorska AE, Zijlstra A, Moses HL. Lack of transforming growth factor-ß signaling promotes collective cancer cell invasion through tumor-stromal crosstalk. Breast Cancer Res. 2012; 14(4):R98. PMID: 22748014; PMCID: PMC3680921.
      17. Novitskiy SV, Pickup MW, Chytil A, Polosukhina D, Owens P, Moses HL. Deletion of TGF-ß signaling in myeloid cells enhances their anti-tumorigenic properties. J Leukoc Biol. 2012 Sep; 92(3):641-51. PMID: 22685318; PMCID: PMC3427612.
      18. Novitskiy SV, Pickup MW, Gorska AE, Owens P, Chytil A, Aakre M, Wu H, Shyr Y, Moses HL. TGF-ß receptor II loss promotes mammary carcinoma progression by Th17 dependent mechanisms. Cancer Discov. 2011 Oct; 1(5):430-41. PMID: 22408746; PMCID: PMC3297196.
      19. Owens P, Pickup MW, Novitskiy SV, Chytil A, Gorska AE, Aakre ME, West J, Moses HL. Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators. Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8):2814-9. PMID: 21576484; PMCID: PMC3286911.
      20. Yan HH, Pickup M, Pang Y, Gorska AE, Li Z, Chytil A, Geng Y, Gray JW, Moses HL, Yang L. Gr-1+CD11b+ myeloid cells tip the balance of immune protection to tumor promotion in the premetastatic lung. Cancer Res. 2010 Aug 1; 70(15):6139-49. PMID: 20631080.
        View in: PubMed
      21. Matise LA, Pickup MW, Moses HL. TGF-beta helps cells fly solo. Nat Cell Biol. 2009 Nov; 11(11):1281-4. PMID: 19838176.
        View in: PubMed
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