Nadine Czudnochowski, PhD

TitleAssistant Researcher
SchoolUCSF School of Medicine
Address513 Parnassus Ave
San Francisco CA 94143
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    1. Czudnochowski N, Ashley GW, Santi DV, Alian A, Finer-Moore J, Stroud RM. The mechanism of pseudouridine synthases from a covalent complex with RNA, and alternate specificity for U2605 versus U2604 between close homologs. Nucleic Acids Res. 2014 Feb; 42(3):2037-48. PMID: 24214967; PMCID: PMC3919597.
    2. Czudnochowski N, Wang AL, Finer-Moore J, Stroud RM. In human pseudouridine synthase 1 (hPus1), a C-terminal helical insert blocks tRNA from binding in the same orientation as in the Pus1 bacterial homologue TruA, consistent with their different target selectivities. J Mol Biol. 2013 Oct 23; 425(20):3875-87. PMID: 23707380; PMCID: PMC3900414.
    3. Czudnochowski N, Bösken CA, Geyer M. Serine-7 but not serine-5 phosphorylation primes RNA polymerase II CTD for P-TEFb recognition. Nat Commun. 2012; 3:842. PMID: 22588304.
      View in: PubMed
    4. Boll A, Jatho A, Czudnochowski N, Geyer M, Steinem C. Mechanistic insights into the translocation of full length HIV-1 Tat across lipid membranes. Biochim Biophys Acta. 2011 Nov; 1808(11):2685-93. PMID: 21819963.
      View in: PubMed
    5. Bigalke JM, Czudnochowski N, Vollmuth F, Vogel-Bachmayr K, Anand K, Geyer M. Formation of Tat-TAR containing ribonucleoprotein complexes for biochemical and structural analyses. Methods. 2011 Jan; 53(1):78-84. PMID: 20385237.
      View in: PubMed
    6. Czudnochowski N, Vollmuth F, Baumann S, Vogel-Bachmayr K, Geyer M. Specificity of Hexim1 and Hexim2 complex formation with cyclin T1/T2, importin alpha and 7SK snRNA. J Mol Biol. 2010 Jan 8; 395(1):28-41. PMID: 19883659.
      View in: PubMed
    7. Barboric M, Yik JH, Czudnochowski N, Yang Z, Chen R, Contreras X, Geyer M, Matija Peterlin B, Zhou Q. Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription. Nucleic Acids Res. 2007; 35(6):2003-12. PMID: 17341462; PMCID: PMC1874611.
    8. Tzokov SB, Wyborn NR, Stillman TJ, Jamieson S, Czudnochowski N, Artymiuk PJ, Green J, Bullough PA. Structure of the hemolysin E (HlyE, ClyA, and SheA) channel in its membrane-bound form. J Biol Chem. 2006 Aug 11; 281(32):23042-9. PMID: 16754675.
      View in: PubMed
    9. Schulte A, Czudnochowski N, Barboric M, Schönichen A, Blazek D, Peterlin BM, Geyer M. Identification of a cyclin T-binding domain in Hexim1 and biochemical analysis of its binding competition with HIV-1 Tat. J Biol Chem. 2005 Jul 1; 280(26):24968-77. PMID: 15855166.
      View in: PubMed
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