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    Nathan Schmidt, PhD

    TitlePostdoctoral Scholar
    SchoolUCSF School of Pharmacy
    DepartmentPharmaceutical Chemistry
    Address555 Mission Bay Blvd South
    San Francisco CA 94158
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Stough JM, Dearth SP, Denny JE, LeCleir GR, Schmidt NW, Campagna SR, Wilhelm SW. Functional Characteristics of the Gut Microbiome in C57BL/6 Mice Differentially Susceptible to Plasmodium yoelii. Front Microbiol. 2016; 7:1520. PMID: 27729904.
        View in: PubMed
      2. Li B, Schmidt NW. Epidermal Fatty Acid Binding Protein (E-FABP) Is Not Required for the Generation or Maintenance of Effector and Memory T Cells following Infection with Listeria monocytogenes. PLoS One. 2016; 11(9):e0162427. PMID: 27588422.
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      3. Realegeno S, Kelly-Scumpia KM, Dang AT, Lu J, Teles R, Liu PT, Schenk M, Lee EY, Schmidt NW, Wong GC, Sarno EN, Rea TH, Ochoa MT, Pellegrini M, Modlin RL. S100A12 Is Part of the Antimicrobial Network against Mycobacterium leprae in Human Macrophages. PLoS Pathog. 2016 Jun; 12(6):e1005705. PMID: 27355424.
        View in: PubMed
      4. Denny JE, Powell WL, Schmidt NW. Local and Long-Distance Calling: Conversations between the Gut Microbiota and Intra- and Extra-Gastrointestinal Tract Infections. Front Cell Infect Microbiol. 2016; 6:41. PMID: 27148490.
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      5. Lee EY, Lee CK, Schmidt NW, Jin F, Lande R, Curk T, Frenkel D, Dobnikar J, Gilliet M, Wong GC. A review of immune amplification via ligand clustering by self-assembled liquid-crystalline DNA complexes. Adv Colloid Interface Sci. 2016 Jun; 232:17-24. PMID: 26956527.
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      6. Villarino NF, LeCleir GR, Denny JE, Dearth SP, Harding CL, Sloan SS, Gribble JL, Campagna SR, Wilhelm SW, Schmidt NW. Composition of the gut microbiota modulates the severity of malaria. Proc Natl Acad Sci U S A. 2016 Feb 23; 113(8):2235-40. PMID: 26858424.
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      7. Schmidt NW, Jin F, Lande R, Curk T, Xian W, Lee C, Frasca L, Frenkel D, Dobnikar J, Gilliet M, Wong GC. Liquid-crystalline ordering of antimicrobial peptide-DNA complexes controls TLR9 activation. Nat Mater. 2015 Jul; 14(7):696-700. PMID: 26053762.
        View in: PubMed
      8. Butler NS, Schmidt NW. Erythropoietin-producing hepatocellular receptor B2 receptor tyrosine kinase: A novel regulator of infection- and inflammation-induced liver fibrosis. Hepatology. 2015 Sep; 62(3):680-3. PMID: 25914283; PMCID: PMC4549189 [Available on 09/01/16].
      9. Kramer JR, Schmidt NW, Mayle KM, Kamei DT, Wong GC, Deming TJ. Reinventing Cell Penetrating Peptides Using Glycosylated Methionine Sulfonium Ion Sequences. ACS Cent Sci. 2015 May 27; 1(2):83-8. PMID: 27162954.
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      10. Villarino N, Denny JE, Schmidt NW. Antimalarial activity of tulathromycin in a murine model of malaria. Antimicrob Agents Chemother. 2015; 59(6):3672-4. PMID: 25870067; PMCID: PMC4432142.
      11. Schmidt NW, Agak GW, Deshayes S, Yu Y, Blacker A, Champer J, Xian W, Kasko AM, Kim J, Wong GC. Pentobra: A Potent Antibiotic with Multiple Layers of Selective Antimicrobial Mechanisms against Propionibacterium Acnes. J Invest Dermatol. 2015 Jun; 135(6):1581-9. PMID: 25668237; PMCID: PMC4430421 [Available on 12/01/15].
      12. White CE, Villarino NF, Sloan SS, Ganusov VV, Schmidt NW. Plasmodium suppresses expansion of T cell responses to heterologous infections. J Immunol. 2015 Jan 15; 194(2):697-708. PMID: 25505280; PMCID: PMC4282975 [Available on 01/15/16].
      13. Schmidt NW, Deshayes S, Hawker S, Blacker A, Kasko AM, Wong GC. Engineering persister-specific antibiotics with synergistic antimicrobial functions. ACS Nano. 2014 Sep 23; 8(9):8786-93. PMID: 25130648; PMCID: PMC4173747.
      14. Lee MW, Chakraborty S, Schmidt NW, Murgai R, Gellman SH, Wong GC. Two interdependent mechanisms of antimicrobial activity allow for efficient killing in nylon-3-based polymeric mimics of innate immunity peptides. Biochim Biophys Acta. 2014 Sep; 1838(9):2269-79. PMID: 24743021; PMCID: PMC4405380.
      15. Schmidt NW, Mishra A, Wang J, DeGrado WF, Wong GC. Influenza virus A M2 protein generates negative Gaussian membrane curvature necessary for budding and scission. J Am Chem Soc. 2013 Sep 18; 135(37):13710-9. PMID: 23962302; PMCID: PMC4000230.
      16. Schmidt NW, Wong GC. Antimicrobial peptides and induced membrane curvature: geometry, coordination chemistry, and molecular engineering. Curr Opin Solid State Mater Sci. 2013 Aug; 17(4):151-163. PMID: 24778573.
        View in: PubMed
      17. Hu K, Schmidt NW, Zhu R, Jiang Y, Lai GH, Wei G, Palermo EF, Kuroda K, Wong GC, Yang L. A critical evaluation of random copolymer mimesis of homogeneous antimicrobial peptides. Macromolecules. 2013; 46(5):1908-1915. PMID: 23750051.
        View in: PubMed
      18. Schmidt NW, Lis M, Zhao K, Lai GH, Alexandrova AN, Tew GN, Wong GC. Molecular basis for nanoscopic membrane curvature generation from quantum mechanical models and synthetic transporter sequences. J Am Chem Soc. 2012 Nov 21; 134(46):19207-16. PMID: 23061419; PMCID: PMC4036524.
      19. Schmidt NW, Tai KP, Kamdar K, Mishra A, Lai GH, Zhao K, Ouellette AJ, Wong GC. Arginine in a-defensins: differential effects on bactericidal activity correspond to geometry of membrane curvature generation and peptide-lipid phase behavior. J Biol Chem. 2012 Jun 22; 287(26):21866-72. PMID: 22566697; PMCID: PMC3381149.
      20. Coridan RH, Schmidt NW, Lai GH, Abbamonte P, Wong GC. Dynamics of confined water reconstructed from inelastic x-ray scattering measurements of bulk response functions. Phys Rev E Stat Nonlin Soft Matter Phys. 2012 Mar; 85(3 Pt 1):031501. PMID: 22587097.
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      21. Mishra A, Lai GH, Schmidt NW, Sun VZ, Rodriguez AR, Tong R, Tang L, Cheng J, Deming TJ, Kamei DT, Wong GC. Translocation of HIV TAT peptide and analogues induced by multiplexed membrane and cytoskeletal interactions. Proc Natl Acad Sci U S A. 2011 Oct 11; 108(41):16883-8. PMID: 21969533; PMCID: PMC3193208.
      22. Schmidt NW, Mishra A, Lai GH, Davis M, Sanders LK, Tran D, Garcia A, Tai KP, McCray PB, Ouellette AJ, Selsted ME, Wong GC. Criterion for amino acid composition of defensins and antimicrobial peptides based on geometry of membrane destabilization. J Am Chem Soc. 2011 May 4; 133(17):6720-7. PMID: 21473577; PMCID: PMC3090259.
      23. Schmidt NW, Harty JT. Cutting edge: attrition of Plasmodium-specific memory CD8 T cells results in decreased protection that is rescued by booster immunization. J Immunol. 2011 Apr 1; 186(7):3836-40. PMID: 21357257; PMCID: PMC3074438.
      24. Mishra A, Tai KP, Schmidt NW, Ouellette AJ, Wong GC. Small-angle X-ray scattering studies of peptide-lipid interactions using the mouse paneth cell a-defensin cryptdin-4. Methods Enzymol. 2011; 492:127-49. PMID: 21333790.
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      25. Abbamonte P, Wong GC, Cahill DG, Reed JP, Coridan RH, Schmidt NW, Lai GH, Joe YI, Casa D. Ultrafast imaging and the phase problem for inelastic X-ray scattering. Adv Mater. 2010 Mar 12; 22(10):1141-7. PMID: 20401938.
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      26. Mylon SE, Rinciog CI, Schmidt N, Gutierrez L, Wong GC, Nguyen TH. Influence of salts and natural organic matter on the stability of bacteriophage MS2. Langmuir. 2010 Jan 19; 26(2):1035-42. PMID: 19775143.
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      27. Coridan RH, Schmidt NW, Lai GH, Godawat R, Krisch M, Garde S, Abbamonte P, Wong GC. Hydration dynamics at femtosecond time scales and angstrom length scales from inelastic x-ray scattering. Phys Rev Lett. 2009 Dec 4; 103(23):237402. PMID: 20366171.
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      28. Schmidt N, Mishra A, Lai GH, Wong GC. Arginine-rich cell-penetrating peptides. FEBS Lett. 2010 May 3; 584(9):1806-13. PMID: 19925791.
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      29. Stark LR, Kruger PB, Rucker FJ, Swanson WH, Schmidt N, Hardy C, Rutman H, Borgovan T, Burke S, Badar M, Shah R. Potential signal to accommodation from the Stiles-Crawford effect and ocular monochromatic aberrations. J Mod Opt. 2009 Nov; 56(20):2203-2216. PMID: 20835401.
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      30. Coridan RH, Schmidt NW, Lai GH, Wong GC. Hydration structures near finite-sized nanoscopic objects reconstructed using inelastic x-ray scattering measurements. J Phys Condens Matter. 2009 Oct 21; 21(42):424115. PMID: 21715850.
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      31. Yang L, Gordon VD, Trinkle DR, Schmidt NW, Davis MA, DeVries C, Som A, Cronan JE, Tew GN, Wong GC. Mechanism of a prototypical synthetic membrane-active antimicrobial: Efficient hole-punching via interaction with negative intrinsic curvature lipids. Proc Natl Acad Sci U S A. 2008 Dec 30; 105(52):20595-600. PMID: 19106303; PMCID: PMC2634941.
      32. Kruger PB, Rucker FJ, Hu C, Rutman H, Schmidt NW, Roditis V. Accommodation with and without short-wavelength-sensitive cones and chromatic aberration. Vision Res. 2005 May; 45(10):1265-74. PMID: 15733959.
        View in: PubMed
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