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    Neil Risch, PhD

    TitleProfessor
    SchoolUCSF School of Medicine
    DepartmentEpidemiology & Biostatistics
    Address513 Parnassus Ave, Med Sci
    San Francisco CA 94143
      Other Positions
      TitleDirector, Institute for Human Genetics


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       Bibliographic 
       Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Hoffmann TJ, Windham GC, Anderson M, Croen LA, Grether JK, Risch N. Evidence of reproductive stoppage in families with autism spectrum disorder: a large, population-based cohort study. JAMA Psychiatry. 2014 Aug 1; 71(8):943-51.
        View in: PubMed
      2. Fears SC, Service SK, Kremeyer B, Araya C, Araya X, Bejarano J, Ramirez M, Castrillón G, Gomez-Franco J, Lopez MC, Montoya G, Montoya P, Aldana I, Teshiba TM, Abaryan Z, Al-Sharif NB, Ericson M, Jalbrzikowski M, Luykx JJ, Navarro L, Tishler TA, Altshuler L, Bartzokis G, Escobar J, Glahn DC, Ospina-Duque J, Risch N, Ruiz-Linares A, Thompson PM, Cantor RM, Lopez-Jaramillo C, Macaya G, Molina J, Reus VI, Sabatti C, Freimer NB, Bearden CE. Multisystem component phenotypes of bipolar disorder for genetic investigations of extended pedigrees. JAMA Psychiatry. 2014 Apr 1; 71(4):375-87.
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      3. Franceschini N, Fox E, Zhang Z, Edwards TL, Nalls MA, Sung YJ, Tayo BO, Sun YV, Gottesman O, Adeyemo A, Johnson AD, Young JH, Rice K, Duan Q, Chen F, Li Y, Tang H, Fornage M, Keene KL, Andrews JS, Smith JA, Faul JD, Guangfa Z, Guo W, Liu Y, Murray SS, Musani SK, Srinivasan S, Velez Edwards DR, Wang H, Becker LC, Bovet P, Bochud M, Broeckel U, Burnier M, Carty C, Chasman DI, Ehret G, Chen WM, Chen G, Chen W, Ding J, Dreisbach AW, Evans MK, Guo X, Garcia ME, Jensen R, Keller MF, Lettre G, Lotay V, Martin LW, Moore JH, Morrison AC, Mosley TH, Ogunniyi A, Palmas W, Papanicolaou G, Penman A, Polak JF, Ridker PM, Salako B, Singleton AB, Shriner D, Taylor KD, Vasan R, Wiggins K, Williams SM, Yanek LR, Zhao W, Zonderman AB, Becker DM, Berenson G, Boerwinkle E, Bottinger E, Cushman M, Eaton C, Nyberg F, Heiss G, Hirschhron JN, Howard VJ, Karczewsk KJ, Lanktree MB, Liu K, Liu Y, Loos R, Margolis K, Snyder M. Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. Am J Hum Genet. 2013 Sep 5; 93(3):545-54.
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      4. Perez MV, Hoffmann TJ, Tang H, Thornton T, Stefanick ML, Larson JC, Kooperberg C, Reiner AP, Caan B, Iribarren C, Risch N. African American race but not genome-wide ancestry is negatively associated with atrial fibrillation among postmenopausal women in the Women's Health Initiative. Am Heart J. 2013 Sep; 166(3):566-72.
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      5. The epilepsy phenome/genome project. Clin Trials. 2013 Aug; 10(4):568-86.
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      6. Coram MA, Duan Q, Hoffmann TJ, Thornton T, Knowles JW, Johnson NA, Ochs-Balcom HM, Donlon TA, Martin LW, Eaton CB, Robinson JG, Risch NJ, Zhu X, Kooperberg C, Li Y, Reiner AP, Tang H. Genome-wide Characterization of Shared and Distinct Genetic Components that Influence Blood Lipid Levels in Ethnically Diverse Human Populations. Am J Hum Genet. 2013 Jun 6; 92(6):904-16.
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      7. Shetty PB, Tang H, Tayo BO, Morrison AC, Hanis CL, Rao DC, Young JH, Fox ER, Boerwinkle E, Cooper RS, Risch NJ, Zhu X. Variants in CXADR and F2RL1 are associated with blood pressure and obesity in African-Americans in regions identified through admixture mapping. J Hypertens. 2012 Oct; 30(10):1970-6.
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      8. Thornton T, Tang H, Hoffmann TJ, Ochs-Balcom HM, Caan BJ, Risch N. Estimating kinship in admixed populations. Am J Hum Genet. 2012 Jul 13; 91(1):122-38.
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      9. Sebro R, Risch NJ. A brief note on the resemblance between relatives in the presence of population stratification. Heredity (Edinb). 2012 May; 108(5):563-8.
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      10. Sebro R, Levy H, Schneck K, Dimmock D, Raby BA, Cannon CL, Broeckel U, Risch NJ. Cystic fibrosis mutations for p.F508del compound heterozygotes predict sweat chloride levels and pancreatic sufficiency. Clin Genet. 2012 Dec; 82(6):546-51.
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      11. Sebro R, Lange C, Laird NM, Rogus JJ, Risch NJ. Differentiating population stratification from genotyping error using family data. Ann Hum Genet. 2012 Jan; 76(1):42-52.
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      12. Hoffmann TJ, Zhan Y, Kvale MN, Hesselson SE, Gollub J, Iribarren C, Lu Y, Mei G, Purdy MM, Quesenberry C, Rowell S, Shapero MH, Smethurst D, Somkin CP, Van den Eeden SK, Walter L, Webster T, Whitmer RA, Finn A, Schaefer C, Kwok PY, Risch N. Design and coverage of high throughput genotyping arrays optimized for individuals of East Asian, African American, and Latino race/ethnicity using imputation and a novel hybrid SNP selection algorithm. Genomics. 2011 Dec; 98(6):422-30.
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      13. Hallmayer J, Cleveland S, Torres A, Phillips J, Cohen B, Torigoe T, Miller J, Fedele A, Collins J, Smith K, Lotspeich L, Croen LA, Ozonoff S, Lajonchere C, Grether JK, Risch N. Genetic heritability and shared environmental factors among twin pairs with autism. Arch Gen Psychiatry. 2011 Nov; 68(11):1095-102.
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      14. Wynshaw-Boris A, Risch N, Motulsky A. Charles Joseph Epstein, M.D., 1933–2011, in memoriam. Am J Hum Genet. 2011 Jun 10; 88(6):684-8.
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      15. Hoffmann TJ, Kvale MN, Hesselson SE, Zhan Y, Aquino C, Cao Y, Cawley S, Chung E, Connell S, Eshragh J, Ewing M, Gollub J, Henderson M, Hubbell E, Iribarren C, Kaufman J, Lao RZ, Lu Y, Ludwig D, Mathauda GK, McGuire W, Mei G, Miles S, Purdy MM, Quesenberry C, Ranatunga D, Rowell S, Sadler M, Shapero MH, Shen L, Shenoy TR, Smethurst D, Van den Eeden SK, Walter L, Wan E, Wearley R, Webster T, Wen CC, Weng L, Whitmer RA, Williams A, Wong SC, Zau C, Finn A, Schaefer C, Kwok PY, Risch N. Next generation genome-wide association tool: design and coverage of a high-throughput European-optimized SNP array. Genomics. 2011 Aug; 98(2):79-89.
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      16. Via M, Gignoux CR, Roth LA, Fejerman L, Galanter J, Choudhry S, Toro-Labrador G, Viera-Vera J, Oleksyk TK, Beckman K, Ziv E, Risch N, Burchard EG, Martínez-Cruzado JC. History shaped the geographic distribution of genomic admixture on the island of Puerto Rico. PLoS One. 2011; 6(1):e16513.
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      17. Kornum BR, Kawashima M, Faraco J, Lin L, Rico TJ, Hesselson S, Axtell RC, Kuipers H, Weiner K, Hamacher A, Kassack MU, Han F, Knudsen S, Li J, Dong X, Winkelmann J, Plazzi G, Nevsimalova S, Hong SC, Honda Y, Honda M, Högl B, Ton TG, Montplaisir J, Bourgin P, Kemlink D, Huang YS, Warby S, Einen M, Eshragh JL, Miyagawa T, Desautels A, Ruppert E, Hesla PE, Poli F, Pizza F, Frauscher B, Jeong JH, Lee SP, Strohl KP, Longstreth WT, Kvale M, Dobrovolna M, Ohayon MM, Nepom GT, Wichmann HE, Rouleau GA, Gieger C, Levinson DF, Gejman PV, Meitinger T, Peppard P, Young T, Jennum P, Steinman L, Tokunaga K, Kwok PY, Risch N, Hallmayer J, Mignot E. Common variants in P2RY11 are associated with narcolepsy. Nat Genet. 2011 Jan; 43(1):66-71.
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      18. Assimes TL, Hólm H, Kathiresan S, Reilly MP, Thorleifsson G, Voight BF, Erdmann J, Willenborg C, Vaidya D, Xie C, Patterson CC, Morgan TM, Burnett MS, Li M, Hlatky MA, Knowles JW, Thompson JR, Absher D, Iribarren C, Go A, Fortmann SP, Sidney S, Risch N, Tang H, Myers RM, Berger K, Stoll M, Shah SH, Thorgeirsson G, Andersen K, Havulinna AS, Herrera JE, Faraday N, Kim Y, Kral BG, Mathias RA, Ruczinski I, Suktitipat B, Wilson AF, Yanek LR, Becker LC, Linsel-Nitschke P, Lieb W, König IR, Hengstenberg C, Fischer M, Stark K, Reinhard W, Winogradow J, Grassl M, Grosshennig A, Preuss M, Schreiber S, Wichmann HE, Meisinger C, Yee J, Friedlander Y, Do R, Meigs JB, Williams G, Nathan DM, MacRae CA, Qu L, Wilensky RL, Matthai WH, Qasim AN, Hakonarson H, Pichard AD, Kent KM, Satler L, Lindsay JM, Waksman R, Knouff CW, Waterworth DM, Walker MC, Mooser VE, Marrugat J, Lucas G, Subirana I, Sala J, Ramos R, Martinelli N, Olivieri O, Trabetti E, Malerba G, Pignatti PF, Guiducci C, Mirel D, Parkin M, Hirschhorn JN, Asselta R, Duga S, Musunuru K, Daly MJ, Purcell S, Eifert S, Braund PS, Wright BJ, Balmforth AJ, Ball SG. Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol. 2010 Nov 2; 56(19):1552-63.
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      19. Sebro R, Hoffman TJ, Lange C, Rogus JJ, Risch NJ. Testing for non-random mating: evidence for ancestry-related assortative mating in the Framingham heart study. Genet Epidemiol. 2010 Nov; 34(7):674-9.
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      20. Peralta CA, Li Y, Wassel C, Choudhry S, Palmas W, Seldin MF, Risch N, Siscovick D, Arnett D, Psaty B, Shlipak MG. Differences in albuminuria between Hispanics and whites: an evaluation by genetic ancestry and country of origin: the multi-ethnic study of atherosclerosis. Circ Cardiovasc Genet. 2010 Jun; 3(3):240-7.
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      21. Lomelin D, Jorgenson E, Risch N. Human genetic variation recognizes functional elements in noncoding sequence. Genome Res. 2010 Mar; 20(3):311-9.
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      22. Zakharia F, Basu A, Absher D, Assimes TL, Go AS, Hlatky MA, Iribarren C, Knowles JW, Li J, Narasimhan B, Sidney S, Southwick A, Myers RM, Quertermous T, Risch N, Tang H. Characterizing the admixed African ancestry of African Americans. Genome Biol. 2009; 10(12):R141.
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      23. Peralta CA, Risch N, Lin F, Shlipak MG, Reiner A, Ziv E, Tang H, Siscovick D, Bibbins-Domingo K. The Association of African Ancestry and elevated creatinine in the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Am J Nephrol. 2010; 31(3):202-8.
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      24. Risch N, Choudhry S, Via M, Basu A, Sebro R, Eng C, Beckman K, Thyne S, Chapela R, Rodriguez-Santana JR, Rodriguez-Cintron W, Avila PC, Ziv E, Gonzalez Burchard E. Ancestry-related assortative mating in Latino populations. Genome Biol. 2009; 10(11):R132.
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      25. Poduri A, Wang Y, Gordon D, Barral-Rodriguez S, Barker-Cummings C, Ulgen A, Chitsazzadeh V, Hill RS, Risch N, Hauser WA, Pedley TA, Walsh CA, Ottman R. Novel susceptibility locus at chromosome 6q16.3-22.31 in a family with GEFS+. Neurology. 2009 Oct 20; 73(16):1264-72.
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      26. Risch N, Herrell R, Lehner T, Liang KY, Eaves L, Hoh J, Griem A, Kovacs M, Ott J, Merikangas KR. Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis. JAMA. 2009 Jun 17; 301(23):2462-71.
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      27. Hallmayer J, Faraco J, Lin L, Hesselson S, Winkelmann J, Kawashima M, Mayer G, Plazzi G, Nevsimalova S, Bourgin P, Hong SC, Hong SS, Honda Y, Honda M, Högl B, Longstreth WT, Montplaisir J, Kemlink D, Einen M, Chen J, Musone SL, Akana M, Miyagawa T, Duan J, Desautels A, Erhardt C, Hesla PE, Poli F, Frauscher B, Jeong JH, Lee SP, Ton TG, Kvale M, Kolesar L, Dobrovolná M, Nepom GT, Salomon D, Wichmann HE, Rouleau GA, Gieger C, Levinson DF, Gejman PV, Meitinger T, Young T, Peppard P, Tokunaga K, Kwok PY, Risch N, Mignot E. Narcolepsy is strongly associated with the T-cell receptor alpha locus. Nat Genet. 2009 Jun; 41(6):708-11.
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      28. Basu A, Tang H, Lewis CE, North K, Curb JD, Quertermous T, Mosley TH, Boerwinkle E, Zhu X, Risch NJ. Admixture mapping of quantitative trait loci for blood lipids in African-Americans. Hum Mol Genet. 2009 Jun 1; 18(11):2091-8.
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      29. Basu A, Tang H, Arnett D, Gu CC, Mosley T, Kardia S, Luke A, Tayo B, Cooper R, Zhu X, Risch N. Admixture mapping of quantitative trait loci for BMI in African Americans: evidence for loci on chromosomes 3q, 5q, and 15q. Obesity (Silver Spring). 2009 Jun; 17(6):1226-31.
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      30. Basu A, Tang H, Zhu X, Gu CC, Hanis C, Boerwinkle E, Risch N. Genome-wide distribution of ancestry in Mexican Americans. Hum Genet. 2008 Oct; 124(3):207-14.
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      31. Assimes TL, Knowles JW, Basu A, Iribarren C, Southwick A, Tang H, Absher D, Li J, Fair JM, Rubin GD, Sidney S, Fortmann SP, Go AS, Hlatky MA, Myers RM, Risch N, Quertermous T. Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study. Hum Mol Genet. 2008 Aug 1; 17(15):2320-8.
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      32. Choudhry S, Taub M, Mei R, Rodriguez-Santana J, Rodriguez-Cintron W, Shriver MD, Ziv E, Risch NJ, Burchard EG. Genome-wide screen for asthma in Puerto Ricans: evidence for association with 5q23 region. Hum Genet. 2008 Jun; 123(5):455-68.
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      33. Knowles JW, Assimes TL, Boerwinkle E, Fortmann SP, Go A, Grove ML, Hlatky M, Iribarren C, Li J, Myers R, Risch N, Sidney S, Southwick A, Volcik KA, Quertermous T. Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD. BMC Med Genet. 2008; 9:23.
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      34. Assimes TL, Knowles JW, Priest JR, Basu A, Volcik KA, Southwick A, Tabor HK, Hartiala J, Allayee H, Grove ML, Tabibiazar R, Sidney S, Fortmann SP, Go A, Hlatky M, Iribarren C, Boerwinkle E, Myers R, Risch N, Quertermous T. Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease. Hum Genet. 2008 May; 123(4):399-408.
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      35. Zhu X, Tang H, Risch N. Admixture mapping and the role of population structure for localizing disease genes. Adv Genet. 2008; 60:547-69.
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      36. DeLuca GC, Ramagopalan SV, Herrera BM, Dyment DA, Lincoln MR, Montpetit A, Pugliatti M, Barnardo MC, Risch NJ, Sadovnick AD, Chao M, Sotgiu S, Hudson TJ, Ebers GC. An extremes of outcome strategy provides evidence that multiple sclerosis severity is determined by alleles at the HLA-DRB1 locus. Proc Natl Acad Sci U S A. 2007 Dec 26; 104(52):20896-901.
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      37. Willer CJ, Dyment DA, Cherny S, Ramagopalan SV, Herrera BM, Morrison KM, Sadovnick AD, Risch NJ, Ebers GC. A genome-wide scan in forty large pedigrees with multiple sclerosis. J Hum Genet. 2007; 52(12):955-62.
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      38. Assimes TL, Knowles JW, Priest JR, Basu A, Borchert A, Volcik KA, Grove ML, Tabor HK, Southwick A, Tabibiazar R, Sidney S, Boerwinkle E, Go AS, Iribarren C, Hlatky MA, Fortmann SP, Myers RM, Kuhn H, Risch N, Quertermous T. A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease. Atherosclerosis. 2008 May; 198(1):136-44.
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      39. Saunders-Pullman R, Raymond D, Senthil G, Kramer P, Ohmann E, Deligtisch A, Shanker V, Greene P, Tabamo R, Huang N, Tagliati M, Kavanagh P, Soto-Valencia J, Aguiar Pde C, Risch N, Ozelius L, Bressman S. Narrowing the DYT6 dystonia region and evidence for locus heterogeneity in the Amish-Mennonites. Am J Med Genet A. 2007 Sep 15; 143A(18):2098-105.
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      40. Marras C, Van den Eeden SK, Fross RD, Benedict-Albers KS, Klingman J, Leimpeter AD, Nelson LM, Risch N, Karter AJ, Bernstein AL, Tanner CM. Minimum incidence of primary cervical dystonia in a multiethnic health care population. Neurology. 2007 Aug 14; 69(7):676-80.
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      41. Tang H, Choudhry S, Mei R, Morgan M, Rodriguez-Cintron W, Burchard EG, Risch NJ. Recent genetic selection in the ancestral admixture of Puerto Ricans. Am J Hum Genet. 2007 Sep; 81(3):626-33.
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      42. Choudhry S, Seibold MA, Borrell LN, Tang H, Serebrisky D, Chapela R, Rodriguez-Santana JR, Avila PC, Ziv E, Rodriguez-Cintron W, Risch NJ, Burchard EG. Dissecting complex diseases in complex populations: asthma in latino americans. Proc Am Thorac Soc. 2007 Jul; 4(3):226-33.
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      43. Dyment DA, Cader MZ, Herrera BM, Ramagopalan SV, Orton SM, Chao M, Willer CJ, Sadovnick AD, Risch N, Ebers GC. A genome scan in a single pedigree with a high prevalence of multiple sclerosis. J Neurol Neurosurg Psychiatry. 2008 Feb; 79(2):158-62.
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      44. Risch NJ, Bressman SB, Senthil G, Ozelius LJ. Intragenic Cis and Trans modification of genetic susceptibility in DYT1 torsion dystonia. Am J Hum Genet. 2007 Jun; 80(6):1188-93.
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      45. Heiman GA, Ottman R, Saunders-Pullman RJ, Ozelius LJ, Risch NJ, Bressman SB. Obsessive-compulsive disorder is not a clinical manifestation of the DYT1 dystonia gene. Am J Med Genet B Neuropsychiatr Genet. 2007 Apr 5; 144B(3):361-4.
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      46. Hsiao CF, Chiu YF, Chiang FT, Ho LT, Lee WJ, Hung YJ, Chen YD, Donlon TA, Jorgenson E, Curb D, Risch N, Hsiung CA. Genome-wide linkage analysis of lipids in nondiabetic Chinese and Japanese from the SAPPHIRe family study. Am J Hypertens. 2006 Dec; 19(12):1270-7.
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      47. Choudhry S, Burchard EG, Borrell LN, Tang H, Gomez I, Naqvi M, Nazario S, Torres A, Casal J, Martinez-Cruzado JC, Ziv E, Avila PC, Rodriguez-Cintron W, Risch NJ. Ancestry-environment interactions and asthma risk among Puerto Ricans. Am J Respir Crit Care Med. 2006 Nov 15; 174(10):1088-93.
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      48. Gunderson EP, Tsai AL, Selby JV, Caan B, Mayer-Davis EJ, Risch N. Twins of mistaken zygosity (TOMZ): evidence for genetic contributions to dietary patterns and physiologic traits. Twin Res Hum Genet. 2006 Aug; 9(4):540-9.
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      49. He XS, Ji X, Hale MB, Cheung R, Ahmed A, Guo Y, Nolan GP, Pfeffer LM, Wright TL, Risch N, Tibshirani R, Greenberg HB. Global transcriptional response to interferon is a determinant of HCV treatment outcome and is modified by race. Hepatology. 2006 Aug; 44(2):352-9.
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      50. Tang H, Coram M, Wang P, Zhu X, Risch N. Reconstructing genetic ancestry blocks in admixed individuals. Am J Hum Genet. 2006 Jul; 79(1):1-12.
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      51. Tang H, Jorgenson E, Gadde M, Kardia SL, Rao DC, Zhu X, Schork NJ, Hanis CL, Risch N. Racial admixture and its impact on BMI and blood pressure in African and Mexican Americans. Hum Genet. 2006 Jul; 119(6):624-33.
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      52. Risch N. Dissecting racial and ethnic differences. N Engl J Med. 2006 Jan 26; 354(4):408-11.
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      53. Ozelius LJ, Senthil G, Saunders-Pullman R, Ohmann E, Deligtisch A, Tagliati M, Hunt AL, Klein C, Henick B, Hailpern SM, Lipton RB, Soto-Valencia J, Risch N, Bressman SB. LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews. N Engl J Med. 2006 Jan 26; 354(4):424-5.
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      54. Urban TJ, Sebro R, Hurowitz EH, Leabman MK, Badagnani I, Lagpacan LL, Risch N, Giacomini KM. Functional genomics of membrane transporters in human populations. Genome Res. 2006 Feb; 16(2):223-30.
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      55. Glatt CE, Carlson E, Taylor TR, Risch N, Reus VI, Schaefer CA. Response to Zhang et al. (2005): loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron 45, 11-16. Neuron. 2005 Dec 8; 48(5):704-5; author reply 705-6.
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      56. Choudhry S, Coyle NE, Tang H, Salari K, Lind D, Clark SL, Tsai HJ, Naqvi M, Phong A, Ung N, Matallana H, Avila PC, Casal J, Torres A, Nazario S, Castro R, Battle NC, Perez-Stable EJ, Kwok PY, Sheppard D, Shriver MD, Rodriguez-Cintron W, Risch N, Ziv E, Burchard EG. Population stratification confounds genetic association studies among Latinos. Hum Genet. 2006 Jan; 118(5):652-64.
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      57. González Burchard E, Borrell LN, Choudhry S, Naqvi M, Tsai HJ, Rodriguez-Santana JR, Chapela R, Rogers SD, Mei R, Rodriguez-Cintron W, Arena JF, Kittles R, Perez-Stable EJ, Ziv E, Risch N. Latino populations: a unique opportunity for the study of race, genetics, and social environment in epidemiological research. Am J Public Health. 2005 Dec; 95(12):2161-8.
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      58. Risch N. The whole side of it--an interview with Neil Risch by Jane Gitschier. PLoS Genet. 2005 Jul 25; 1(1):e14.
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      59. Risch N. The whole side of it--an interview with Neil Risch. Interview by Jane Gitschier. PLoS Genet. 2005 Jul; 1(1):3-5.
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      60. Salari K, Choudhry S, Tang H, Naqvi M, Lind D, Avila PC, Coyle NE, Ung N, Nazario S, Casal J, Torres-Palacios A, Clark S, Phong A, Gomez I, Matallana H, Pérez-Stable EJ, Shriver MD, Kwok PY, Sheppard D, Rodriguez-Cintron W, Risch NJ, Burchard EG, Ziv E. Genetic admixture and asthma-related phenotypes in Mexican American and Puerto Rican asthmatics. Genet Epidemiol. 2005 Jul; 29(1):76-86.
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      61. Dyment DA, Herrera BM, Cader MZ, Willer CJ, Lincoln MR, Sadovnick AD, Risch N, Ebers GC. Complex interactions among MHC haplotypes in multiple sclerosis: susceptibility and resistance. Hum Mol Genet. 2005 Jul 15; 14(14):2019-26.
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      62. Tang H, Peng J, Wang P, Risch NJ. Estimation of individual admixture: analytical and study design considerations. Genet Epidemiol. 2005 May; 28(4):289-301.
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      63. Chiu YF, Chuang LM, Hsiao CF, Hung YJ, Lin MW, Chen YT, Grove J, Jorgenson E, Quertermous T, Risch N, Hsiung CA. An autosomal genome-wide scan for loci linked to pre-diabetic phenotypes in nondiabetic Chinese subjects from the Stanford Asia-Pacific Program of Hypertension and Insulin Resistance Family Study. Diabetes. 2005 Apr; 54(4):1200-6.
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      64. Risch N. 2004 Curt Stern Award Address. The SNP endgame: a multidisciplinary approach. Am J Hum Genet. 2005 Feb; 76(2):221-6.
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      65. Zhu X, Luke A, Cooper RS, Quertermous T, Hanis C, Mosley T, Gu CC, Tang H, Rao DC, Risch N, Weder A. Admixture mapping for hypertension loci with genome-scan markers. Nat Genet. 2005 Feb; 37(2):177-81.
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      66. Urban TJ, Giacomini KM, Risch N. Haplotype structure and ethnic-specific allele frequencies at the OCTN locus: implications for the genetics of Crohn's disease. Inflamm Bowel Dis. 2005 Jan; 11(1):78-9.
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      67. Jorgenson E, Tang H, Gadde M, Province M, Leppert M, Kardia S, Schork N, Cooper R, Rao DC, Boerwinkle E, Risch N. Ethnicity and human genetic linkage maps. Am J Hum Genet. 2005 Feb; 76(2):276-90.
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      68. Tang H, Quertermous T, Rodriguez B, Kardia SL, Zhu X, Brown A, Pankow JS, Province MA, Hunt SC, Boerwinkle E, Schork NJ, Risch NJ. Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies. Am J Hum Genet. 2005 Feb; 76(2):268-75.
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      69. Mountain JL, Risch N. Assessing genetic contributions to phenotypic differences among 'racial' and 'ethnic' groups. Nat Genet. 2004 Nov; 36(11 Suppl):S48-53.
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      70. Ekstein J, Rubin BY, Anderson SL, Weinstein DA, Bach G, Abeliovich D, Webb M, Risch N. Mutation frequencies for glycogen storage disease Ia in the Ashkenazi Jewish population. Am J Med Genet A. 2004 Aug 30; 129A(2):162-4.
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      71. Heiman GA, Ottman R, Saunders-Pullman RJ, Ozelius LJ, Risch NJ, Bressman SB. Increased risk for recurrent major depression in DYT1 dystonia mutation carriers. Neurology. 2004 Aug 24; 63(4):631-7.
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      72. Dyment DA, Steckley JL, Morrison K, Willer CJ, Cader MZ, DeLuca GC, Sadovnick AD, Risch N, Ebers GC. TCR beta polymorphisms and multiple sclerosis. Genes Immun. 2004 Aug; 5(5):337-42.
        View in: PubMed
      73. Huang J, Lin A, Narasimhan B, Quertermous T, Hsiung CA, Ho LT, Grove JS, Olivier M, Ranade K, Risch NJ, Olshen RA. Tree-structured supervised learning and the genetics of hypertension. Proc Natl Acad Sci U S A. 2004 Jul 20; 101(29):10529-34.
        View in: PubMed
      74. Ebers GC, Sadovnick AD, Dyment DA, Yee IM, Willer CJ, Risch N. Parent-of-origin effect in multiple sclerosis: observations in half-siblings. Lancet. 2004 May 29; 363(9423):1773-4.
        View in: PubMed
      75. Dyment DA, Sadovnick AD, Willer CJ, Armstrong H, Cader ZM, Wiltshire S, Kalman B, Risch N, Ebers GC. An extended genome scan in 442 Canadian multiple sclerosis-affected sibships: a report from the Canadian Collaborative Study Group. Hum Mol Genet. 2004 May 15; 13(10):1005-15.
        View in: PubMed
      76. Li J, Nguyen L, Gleason C, Lotspeich L, Spiker D, Risch N, Myers RM. Lack of evidence for an association between WNT2 and RELN polymorphisms and autism. Am J Med Genet B Neuropsychiatr Genet. 2004 Apr 1; 126B(1):51-7.
        View in: PubMed
      77. Tukel T, Shalata A, Present D, Rachmilewitz D, Mayer L, Grant D, Risch N, Desnick RJ. Crohn disease: frequency and nature of CARD15 mutations in Ashkenazi and Sephardi/Oriental Jewish families. Am J Hum Genet. 2004 Apr; 74(4):623-36.
        View in: PubMed
      78. Merikangas KR, Risch N. Genomic priorities and public health. Science. 2003 Oct 24; 302(5645):599-601.
        View in: PubMed
      79. Willer CJ, Dyment DA, Risch NJ, Sadovnick AD, Ebers GC. Twin concordance and sibling recurrence rates in multiple sclerosis. Proc Natl Acad Sci U S A. 2003 Oct 28; 100(22):12877-82.
        View in: PubMed
      80. McIntire JJ, Umetsu SE, Macaubas C, Hoyte EG, Cinnioglu C, Cavalli-Sforza LL, Barsh GS, Hallmayer JF, Underhill PA, Risch NJ, Freeman GJ, DeKruyff RH, Umetsu DT. Immunology: hepatitis A virus link to atopic disease. Nature. 2003 Oct 9; 425(6958):576.
        View in: PubMed
      81. Varon R, Gooding R, Steglich C, Marns L, Tang H, Angelicheva D, Yong KK, Ambrugger P, Reinhold A, Morar B, Baas F, Kwa M, Tournev I, Guerguelcheva V, Kremensky I, Lochmüller H, Müllner-Eidenböck A, Merlini L, Neumann L, Bürger J, Walter M, Swoboda K, Thomas PK, von Moers A, Risch N, Kalaydjieva L. Partial deficiency of the C-terminal-domain phosphatase of RNA polymerase II is associated with congenital cataracts facial dysmorphism neuropathy syndrome. Nat Genet. 2003 Oct; 35(2):185-9.
        View in: PubMed
      82. Leabman MK, Huang CC, DeYoung J, Carlson EJ, Taylor TR, de la Cruz M, Johns SJ, Stryke D, Kawamoto M, Urban TJ, Kroetz DL, Ferrin TE, Clark AG, Risch N, Herskowitz I, Giacomini KM. Natural variation in human membrane transporter genes reveals evolutionary and functional constraints. Proc Natl Acad Sci U S A. 2003 May 13; 100(10):5896-901.
        View in: PubMed
      83. Merikangas KR, Risch N. Will the genomics revolution revolutionize psychiatry? Am J Psychiatry. 2003 Apr; 160(4):625-35.
        View in: PubMed
      84. Burchard EG, Ziv E, Coyle N, Gomez SL, Tang H, Karter AJ, Mountain JL, Pérez-Stable EJ, Sheppard D, Risch N. The importance of race and ethnic background in biomedical research and clinical practice. N Engl J Med. 2003 Mar 20; 348(12):1170-5.
        View in: PubMed
      85. Botstein D, Risch N. Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease. Nat Genet. 2003 Mar; 33 Suppl:228-37.
        View in: PubMed
      86. Risch N, Tang H, Katzenstein H, Ekstein J. Geographic distribution of disease mutations in the Ashkenazi Jewish population supports genetic drift over selection. Am J Hum Genet. 2003 Apr; 72(4):812-22.
        View in: PubMed
      87. Kim UK, Jorgenson E, Coon H, Leppert M, Risch N, Drayna D. Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide. Science. 2003 Feb 21; 299(5610):1221-5.
        View in: PubMed
      88. Ranade K, Hinds D, Hsiung CA, Chuang LM, Chang MS, Chen YT, Pesich R, Hebert J, Chen YD, Dzau V, Olshen R, Curb D, Botstein D, Cox DR, Risch N. A genome scan for hypertension susceptibility loci in populations of Chinese and Japanese origins. Am J Hypertens. 2003 Feb; 16(2):158-62.
        View in: PubMed
      89. Province MA, Kardia SL, Ranade K, Rao DC, Thiel BA, Cooper RS, Risch N, Turner ST, Cox DR, Hunt SC, Weder AB, Boerwinkle E. A meta-analysis of genome-wide linkage scans for hypertension: the National Heart, Lung and Blood Institute Family Blood Pressure Program. Am J Hypertens. 2003 Feb; 16(2):144-7.
        View in: PubMed
      90. Drayna D, Kim UK, Coon H, Jorgenson E, Risch N, Leppert M. A model system for identifying genes underlying complex traits. Cold Spring Harb Symp Quant Biol. 2003; 68:365-71.
        View in: PubMed
      91. Bressman SB, Raymond D, Wendt K, Saunders-Pullman R, De Leon D, Fahn S, Ozelius L, Risch N. Diagnostic criteria for dystonia in DYT1 families. Neurology. 2002 Dec 10; 59(11):1780-2.
        View in: PubMed
      92. Shifman S, Bronstein M, Sternfeld M, Pisanté-Shalom A, Lev-Lehman E, Weizman A, Reznik I, Spivak B, Grisaru N, Karp L, Schiffer R, Kotler M, Strous RD, Swartz-Vanetik M, Knobler HY, Shinar E, Beckmann JS, Yakir B, Risch N, Zak NB, Darvasi A. A highly significant association between a COMT haplotype and schizophrenia. Am J Hum Genet. 2002 Dec; 71(6):1296-302.
        View in: PubMed
      93. Merikangas KR, Chakravarti A, Moldin SO, Araj H, Blangero JC, Burmeister M, Crabbe J, Depaulo JR, Foulks E, Freimer NB, Koretz DS, Lichtenstein W, Mignot E, Reiss AL, Risch NJ, Takahashi JS. Future of genetics of mood disorders research. Biol Psychiatry. 2002 Sep 15; 52(6):457-77.
        View in: PubMed
      94. Hallmayer J, Glasson EJ, Bower C, Petterson B, Croen L, Grether J, Risch N. On the twin risk in autism. Am J Hum Genet. 2002 Oct; 71(4):941-6.
        View in: PubMed
      95. Dyment DA, Cader MZ, Willer CJ, Risch N, Sadovnick AD, Ebers GC. A multigenerational family with multiple sclerosis. Brain. 2002 Jul; 125(Pt 7):1474-82.
        View in: PubMed
      96. Risch N, Burchard E, Ziv E, Tang H. Categorization of humans in biomedical research: genes, race and disease. Genome Biol. 2002 Jul 1; 3(7):comment2007.
        View in: PubMed
      97. Tabor HK, Risch NJ, Myers RM. Candidate-gene approaches for studying complex genetic traits: practical considerations. Nat Rev Genet. 2002 May; 3(5):391-7.
        View in: PubMed
      98. Sabatti C, Risch N. Homozygosity and linkage disequilibrium. Genetics. 2002 Apr; 160(4):1707-19.
        View in: PubMed
      99. Spiker D, Lotspeich LJ, Dimiceli S, Myers RM, Risch N. Behavioral phenotypic variation in autism multiplex families: evidence for a continuous severity gradient. Am J Med Genet. 2002 Mar 8; 114(2):129-36.
        View in: PubMed
      100. Ranade K, Jorgenson E, Sheu WH, Pei D, Hsiung CA, Chiang FT, Chen YD, Pratt R, Olshen RA, Curb D, Cox DR, Botstein D, Risch N. A polymorphism in the beta1 adrenergic receptor is associated with resting heart rate. Am J Hum Genet. 2002 Apr; 70(4):935-42.
        View in: PubMed
      101. Dyment DA, Steckley JL, Willer CJ, Armstrong H, Sadovnick AD, Risch N, Ebers GC. No evidence to support CTLA-4 as a susceptibility gene in MS families: the Canadian Collaborative Study. J Neuroimmunol. 2002 Feb; 123(1-2):193-8.
        View in: PubMed
      102. Saunders-Pullman R, Shriberg J, Heiman G, Raymond D, Wendt K, Kramer P, Schilling K, Kurlan R, Klein C, Ozelius LJ, Risch NJ, Bressman SB. Myoclonus dystonia: possible association with obsessive-compulsive disorder and alcohol dependence. Neurology. 2002 Jan 22; 58(2):242-5.
        View in: PubMed
      103. Risch N, Piazza A, Cavalli-Sforza LL. Dropped genetics paper lacked scientific merit. Nature. 2002 Jan 10; 415(6868):115.
        View in: PubMed
      104. Li J, Tabor HK, Nguyen L, Gleason C, Lotspeich LJ, Spiker D, Risch N, Myers RM. Lack of association between HoxA1 and HoxB1 gene variants and autism in 110 multiplex families. Am J Med Genet. 2002 Jan 8; 114(1):24-30.
        View in: PubMed
      105. Ranade K, Shue WH, Hung YJ, Hsuing CA, Chiang FT, Pesich R, Hebert J, Olivier M, Chen YD, Pratt R, Olshen R, Curb D, Botstein D, Risch N, Cox DR. The glycine allele of a glycine/arginine polymorphism in the beta2-adrenergic receptor gene is associated with essential hypertension in a population of Chinese origin. Am J Hypertens. 2001 Dec; 14(12):1196-200.
        View in: PubMed
      106. Risch N. Implications of multilocus inheritance for gene-disease association studies. Theor Popul Biol. 2001 Nov; 60(3):215-20.
        View in: PubMed
      107. Ranade K, Wu KD, Risch N, Olivier M, Pei D, Hsiao CF, Chuang LM, Ho LT, Jorgenson E, Pesich R, Chen YD, Dzau V, Lin A, Olshen RA, Curb D, Cox DR, Botstein D. Genetic variation in aldosterone synthase predicts plasma glucose levels. Proc Natl Acad Sci U S A. 2001 Nov 6; 98(23):13219-24.
        View in: PubMed
      108. Liu JS, Sabatti C, Teng J, Keats BJ, Risch N. Bayesian analysis of haplotypes for linkage disequilibrium mapping. Genome Res. 2001 Oct; 11(10):1716-24.
        View in: PubMed
      109. Spiker D, Lotspeich LJ, Dimiceli S, Szatmari P, Myers RM, Risch N. Birth order effects on nonverbal IQ scores in autism multiplex families. J Autism Dev Disord. 2001 Oct; 31(5):449-60.
        View in: PubMed
      110. Ranade K, Wu KD, Hwu CM, Ting CT, Pei D, Pesich R, Hebert J, Chen YD, Pratt R, Olshen R, Masaki K, Risch N, Cox DR, Botstein D. Genetic variation in the human urea transporter-2 is associated with variation in blood pressure. Hum Mol Genet. 2001 Sep 15; 10(19):2157-64.
        View in: PubMed
      111. Ligers A, Dyment DA, Willer CJ, Sadovnick AD, Ebers G, Risch N, Hillert J. Evidence of linkage with HLA-DR in DRB1*15-negative families with multiple sclerosis. Am J Hum Genet. 2001 Oct; 69(4):900-3.
        View in: PubMed
      112. Dyment DA, Willer CJ, Scott B, Armstrong H, Ligers A, Hillert J, Paty DW, Hashimoto S, Devonshire V, Hooge J, Kastrukoff L, Oger J, Metz L, Warren S, Hader W, Power C, Auty A, Nath A, Nelson R, Freedman M, Brunet D, Paulseth JE, Rice G, O'Connor P, Duquette P, Lapierre Y, Francis G, Bouchard JP, Murray TJ, Bhan V, Maxner C, Pryse-Phillips W, Stefanelli M, Sadovnick AD, Risch N, Ebers GC. Genetic susceptibility to MS: a second stage analysis in Canadian MS families. Neurogenetics. 2001 Jul; 3(3):145-51.
        View in: PubMed
      113. Risch N. The genetic epidemiology of cancer: interpreting family and twin studies and their implications for molecular genetic approaches. Cancer Epidemiol Biomarkers Prev. 2001 Jul; 10(7):733-41.
        View in: PubMed
      114. Ranade K, Chang MS, Ting CT, Pei D, Hsiao CF, Olivier M, Pesich R, Hebert J, Chen YD, Dzau VJ, Curb D, Olshen R, Risch N, Cox DR, Botstein D. High-throughput genotyping with single nucleotide polymorphisms. Genome Res. 2001 Jul; 11(7):1262-8.
        View in: PubMed
      115. Glatt CE, DeYoung JA, Delgado S, Service SK, Giacomini KM, Edwards RH, Risch N, Freimer NB. Screening a large reference sample to identify very low frequency sequence variants: comparisons between two genes. Nat Genet. 2001 Apr; 27(4):435-8.
        View in: PubMed
      116. Bressman SB, Fahn S, Ozelius LJ, Kramer PL, Risch NJ. The DYT1 mutation and nonfamilial primary torsion dystonia. Arch Neurol. 2001 Apr; 58(4):681-2.
        View in: PubMed
      117. Bach G, Tomczak J, Risch N, Ekstein J. Tay-Sachs screening in the Jewish Ashkenazi population: DNA testing is the preferred procedure. Am J Med Genet. 2001 Feb 15; 99(1):70-5.
        View in: PubMed
      118. Mignot E, Lin L, Rogers W, Honda Y, Qiu X, Lin X, Okun M, Hohjoh H, Miki T, Hsu S, Leffell M, Grumet F, Fernandez-Vina M, Honda M, Risch N. Complex HLA-DR and -DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups. Am J Hum Genet. 2001 Mar; 68(3):686-99.
        View in: PubMed
      119. Risch N. Molecular epidemiology of Tay-Sachs disease. Adv Genet. 2001; 44:233-52.
        View in: PubMed
      120. Baharloo S, Service SK, Risch N, Gitschier J, Freimer NB. Familial aggregation of absolute pitch. Am J Hum Genet. 2000 Sep; 67(3):755-8.
        View in: PubMed
      121. Province MA, Boerwinkle E, Chakravarti A, Cooper R, Fornage M, Leppert M, Risch N, Ranade K. Lack of association of the angiotensinogen-6 polymorphism with blood pressure levels in the comprehensive NHLBI Family Blood Pressure Program. National Heart, Lung and Blood Institute. J Hypertens. 2000 Jul; 18(7):867-76.
        View in: PubMed
      122. Risch NJ. Searching for genetic determinants in the new millennium. Nature. 2000 Jun 15; 405(6788):847-56.
        View in: PubMed
      123. Ranade K, Hsuing AC, Wu KD, Chang MS, Chen YT, Hebert J, Chen YI, Olshen R, Curb D, Dzau V, Botstein D, Cox D, Risch N. Lack of evidence for an association between alpha-adducin and blood pressure regulation in Asian populations. Am J Hypertens. 2000 Jun; 13(6 Pt 1):704-9.
        View in: PubMed
      124. Risch N. Searching for genes in complex diseases: lessons from systemic lupus erythematosus. J Clin Invest. 2000 Jun; 105(11):1503-6.
        View in: PubMed
      125. Bressman SB, Sabatti C, Raymond D, de Leon D, Klein C, Kramer PL, Brin MF, Fahn S, Breakefield X, Ozelius LJ, Risch NJ. The DYT1 phenotype and guidelines for diagnostic testing. Neurology. 2000 May 9; 54(9):1746-52.
        View in: PubMed
      126. Diaz GA, Gelb BD, Risch N, Nygaard TG, Frisch A, Cohen IJ, Miranda CS, Amaral O, Maire I, Poenaru L, Caillaud C, Weizberg M, Mistry P, Desnick RJ. Gaucher disease: the origins of the Ashkenazi Jewish N370S and 84GG acid beta-glucosidase mutations. Am J Hum Genet. 2000 Jun; 66(6):1821-32.
        View in: PubMed
      127. Steckley JL, Dyment DA, Sadovnick AD, Risch N, Hayes C, Ebers GC. Genetic analysis of vitamin D related genes in Canadian multiple sclerosis patients. Canadian Collaborative Study Group. Neurology. 2000 Feb 8; 54(3):729-32.
        View in: PubMed
      128. Lyons DM, Martel FL, Levine S, Risch NJ, Schatzberg AF. Postnatal experiences and genetic effects on squirrel monkey social affinities and emotional distress. Horm Behav. 1999 Dec; 36(3):266-75.
        View in: PubMed
      129. Salmon B, Hallmayer J, Rogers T, Kalaydjieva L, Petersen PB, Nicholas P, Pingree C, McMahon W, Spiker D, Lotspeich L, Kraemer H, McCague P, Dimiceli S, Nouri N, Pitts T, Yang J, Hinds D, Myers RM, Risch N. Absence of linkage and linkage disequilibrium to chromosome 15q11-q13 markers in 139 multiplex families with autism. Am J Med Genet. 1999 Oct 15; 88(5):551-6.
        View in: PubMed
      130. Risch N, Spiker D, Lotspeich L, Nouri N, Hinds D, Hallmayer J, Kalaydjieva L, McCague P, Dimiceli S, Pitts T, Nguyen L, Yang J, Harper C, Thorpe D, Vermeer S, Young H, Hebert J, Lin A, Ferguson J, Chiotti C, Wiese-Slater S, Rogers T, Salmon B, Nicholas P, Petersen PB, Pingree C, McMahon W, Wong DL, Cavalli-Sforza LL, Kraemer HC, Myers RM. A genomic screen of autism: evidence for a multilocus etiology. Am J Hum Genet. 1999 Aug; 65(2):493-507.
        View in: PubMed
      131. Klein C, Vieregge P, Hagenah J, Sieberer M, Doyle E, Jacobs H, Gasser T, Breakefield XO, Risch NJ, Ozelius LJ. Search for the PARK3 founder haplotype in a large cohort of patients with Parkinson's disease from northern Germany. Ann Hum Genet. 1999 Jul; 63(Pt 4):285-91.
        View in: PubMed
      132. Rogers T, Kalaydjieva L, Hallmayer J, Petersen PB, Nicholas P, Pingree C, McMahon WM, Spiker D, Lotspeich L, Kraemer H, McCague P, Dimiceli S, Nouri N, Peachy T, Yang J, Hinds D, Risch N, Myers RM. Exclusion of linkage to the HLA region in ninety multiplex sibships with autism. J Autism Dev Disord. 1999 Jun; 29(3):195-201.
        View in: PubMed
      133. Rice G, Anderson C, Risch N, Ebers G. Male homosexuality: absence of linkage to microsatellite markers at Xq28. Science. 1999 Apr 23; 284(5414):665-7.
        View in: PubMed
      134. Teng J, Risch N. The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases. II. Individual genotyping. Genome Res. 1999 Mar; 9(3):234-41.
        View in: PubMed
      135. Jorgenson E, Hinds D, Risch N. Sib-pair analysis of the collaborative study on the genetics of alcoholism data set. Genet Epidemiol. 1999; 17 Suppl 1:S187-91.
        View in: PubMed
      136. Klein C, Ozelius LJ, Hagenah J, Breakefield XO, Risch NJ, Vieregge P. Search for a founder mutation in idiopathic focal dystonia from Northern Germany. Am J Hum Genet. 1998 Dec; 63(6):1777-82.
        View in: PubMed
      137. Risch N, Teng J. The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases I. DNA pooling. Genome Res. 1998 Dec; 8(12):1273-88.
        View in: PubMed
      138. Sadovnick AD, Risch NJ, Ebers GC. Canadian collaborative project on genetic susceptibility to MS, phase 2: rationale and method. Canadian Collaborative Study Group. Can J Neurol Sci. 1998 Aug; 25(3):216-21.
        View in: PubMed
      139. Merikangas KR, Stevens DE, Fenton B, Stolar M, O'Malley S, Woods SW, Risch N. Co-morbidity and familial aggregation of alcoholism and anxiety disorders. Psychol Med. 1998 Jul; 28(4):773-88.
        View in: PubMed
      140. Klein C, Brin MF, de Leon D, Limborska SA, Ivanova-Smolenskaya IA, Bressman SB, Friedman A, Markova ED, Risch NJ, Breakefield XO, Ozelius LJ. De novo mutations (GAG deletion) in the DYT1 gene in two non-Jewish patients with early-onset dystonia. Hum Mol Genet. 1998 Jul; 7(7):1133-6.
        View in: PubMed
      141. Concannon P, Gogolin-Ewens KJ, Hinds DA, Wapelhorst B, Morrison VA, Stirling B, Mitra M, Farmer J, Williams SR, Cox NJ, Bell GI, Risch N, Spielman RS. A second-generation screen of the human genome for susceptibility to insulin-dependent diabetes mellitus. Nat Genet. 1998 Jul; 19(3):292-6.
        View in: PubMed
      142. Ottman R, Lee JH, Hauser WA, Risch N. Are generalized and localization-related epilepsies genetically distinct? Arch Neurol. 1998 Mar; 55(3):339-44.
        View in: PubMed
      143. Sadovnick AD, Yee IM, Ebers GC, Risch NJ. Effect of age at onset and parental disease status on sibling risks for MS. Neurology. 1998 Mar; 50(3):719-23.
        View in: PubMed
      144. Bressman SB, de Leon D, Raymond D, Ozelius LJ, Breakefield XO, Nygaard TG, Almasy L, Risch NJ, Kramer PL. Clinical-genetic spectrum of primary dystonia. Adv Neurol. 1998; 78:79-91.
        View in: PubMed
      145. Ozelius LJ, Hewett JW, Page CE, Bressman SB, Kramer PL, Shalish C, de Leon D, Brin MF, Raymond D, Jacoby D, Penney J, Risch NJ, Fahn S, Gusella JF, Breakefield XO. The gene (DYT1) for early-onset torsion dystonia encodes a novel protein related to the Clp protease/heat shock family. Adv Neurol. 1998; 78:93-105.
        View in: PubMed
      146. Bressman SB, de Leon D, Raymond D, Greene PE, Brin MF, Fahn S, Ozelius LJ, Breakefield XO, Kramer PL, Risch NJ. The role of the DYT1 gene in secondary dystonia. Adv Neurol. 1998; 78:107-15.
        View in: PubMed
      147. Pelin Z, Guilleminault C, Risch N, Grumet FC, Mignot E. HLA-DQB1*0602 homozygosity increases relative risk for narcolepsy but not disease severity in two ethnic groups. US Modafinil in Narcolepsy Multicenter Study Group. Tissue Antigens. 1998 Jan; 51(1):96-100.
        View in: PubMed
      148. Risch N. Haemochromatosis, HFE and genetic complexity. Nat Genet. 1997 Dec; 17(4):375-6.
        View in: PubMed
      149. Almasy L, Bressman SB, Raymond D, Kramer PL, Greene PE, Heiman GA, Ford B, Yount J, de Leon D, Chouinard S, Saunders-Pullman R, Brin MF, Kapoor RP, Jones AC, Shen H, Fahn S, Risch NJ, Nygaard TG. Idiopathic torsion dystonia linked to chromosome 8 in two Mennonite families. Ann Neurol. 1997 Oct; 42(4):670-3.
        View in: PubMed
      150. Farrer LA, Cupples LA, Haines JL, Hyman B, Kukull WA, Mayeux R, Myers RH, Pericak-Vance MA, Risch N, van Duijn CM. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. JAMA. 1997 Oct 22-29; 278(16):1349-56.
        View in: PubMed
      151. Ozelius LJ, Hewett JW, Page CE, Bressman SB, Kramer PL, Shalish C, de Leon D, Brin MF, Raymond D, Corey DP, Fahn S, Risch NJ, Buckler AJ, Gusella JF, Breakefield XO. The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein. Nat Genet. 1997 Sep; 17(1):40-8.
        View in: PubMed
      152. Almasy L, Bressman S, de Leon D, Risch N. Ethnic variation in the clinical expression of idiopathic torsion dystonia. Mov Disord. 1997 Sep; 12(5):715-21.
        View in: PubMed
      153. Bressman SB, de Leon D, Raymond D, Greene PE, Brin MF, Fahn S, Ozelius LJ, Breakefield XO, Kramer PL, Risch NJ. Secondary dystonia and the DYTI gene. Neurology. 1997 Jun; 48(6):1571-7.
        View in: PubMed
      154. Mansfield TA, Simon DB, Farfel Z, Bia M, Tucci JR, Lebel M, Gutkin M, Vialettes B, Christofilis MA, Kauppinen-Makelin R, Mayan H, Risch N, Lifton RP. Multilocus linkage of familial hyperkalaemia and hypertension, pseudohypoaldosteronism type II, to chromosomes 1q31-42 and 17p11-q21. Nat Genet. 1997 Jun; 16(2):202-5.
        View in: PubMed
      155. Ozelius LJ, Hewett J, Kramer P, Bressman SB, Shalish C, de Leon D, Rutter M, Risch N, Brin MF, Markova ED, Limborska SA, Ivanova-Smolenskaya IA, McCormick MK, Fahn S, Buckler AJ, Gusella JF, Breakefield XO. Fine localization of the torsion dystonia gene (DYT1) on human chromosome 9q34: YAC map and linkage disequilibrium. Genome Res. 1997 May; 7(5):483-94.
        View in: PubMed
      156. Merikangas KR, Fenton BT, Cheng SH, Stolar MJ, Risch N. Association between migraine and stroke in a large-scale epidemiological study of the United States. Arch Neurol. 1997 Apr; 54(4):362-8.
        View in: PubMed
      157. Uhl GR, Gold LH, Risch N. Genetic analyses of complex behavioral disorders. Proc Natl Acad Sci U S A. 1997 Apr 1; 94(7):2785-6.
        View in: PubMed
      158. Ottman R, Hauser WA, Barker-Cummings C, Lee JH, Risch N. Segregation analysis of cryptogenic epilepsy and an empirical test of the validity of the results. Am J Hum Genet. 1997 Mar; 60(3):667-75.
        View in: PubMed
      159. Risch N. Evolving methods in genetic epidemiology. II. Genetic linkage from an epidemiologic perspective. Epidemiol Rev. 1997; 19(1):24-32.
        View in: PubMed
      160. Hallmayer J, Hebert JM, Spiker D, Lotspeich L, McMahon WM, Petersen PB, Nicholas P, Pingree C, Lin AA, Cavalli-Sforza LL, Risch N, Ciaranello RD. Autism and the X chromosome. Multipoint sib-pair analysis. Arch Gen Psychiatry. 1996 Nov; 53(11):985-9.
        View in: PubMed
      161. Zhang H, Risch N. Mapping quantitative-trait loci in humans by use of extreme concordant sib pairs: selected sampling by parental phenotypes. Am J Hum Genet. 1996 Oct; 59(4):951-7.
        View in: PubMed
      162. Bressman SB, Warner TT, Almasy L, Uitti RJ, Greene PE, Heiman GA, Raymond D, Ford B, de Leon D, Fahn S, Kramer PL, Risch NJ, Maraganore DM, Nygaard TG, Harding AE. Exclusion of the DYT1 locus in familial torticollis. Ann Neurol. 1996 Oct; 40(4):681-4.
        View in: PubMed
      163. Risch N, Merikangas K. The future of genetic studies of complex human diseases. Science. 1996 Sep 13; 273(5281):1516-7.
        View in: PubMed
      164. Devlin B, Risch N, Roeder K. Disequilibrium mapping: composite likelihood for pairwise disequilibrium. Genomics. 1996 Aug 15; 36(1):1-16.
        View in: PubMed
      165. Feder JN, Gnirke A, Thomas W, Tsuchihashi Z, Ruddy DA, Basava A, Dormishian F, Domingo R, Ellis MC, Fullan A, Hinton LM, Jones NL, Kimmel BE, Kronmal GS, Lauer P, Lee VK, Loeb DB, Mapa FA, McClelland E, Meyer NC, Mintier GA, Moeller N, Moore T, Morikang E, Prass CE, Quintana L, Starnes SM, Schatzman RC, Brunke KJ, Drayna DT, Risch NJ, Bacon BR, Wolff RK. A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nat Genet. 1996 Aug; 13(4):399-408.
        View in: PubMed
      166. Ebers GC, Kukay K, Bulman DE, Sadovnick AD, Rice G, Anderson C, Armstrong H, Cousin K, Bell RB, Hader W, Paty DW, Hashimoto S, Oger J, Duquette P, Warren S, Gray T, O'Connor P, Nath A, Auty A, Metz L, Francis G, Paulseth JE, Murray TJ, Pryse-Phillips W, Nelson R, Freedman M, Brunet D, Bouchard JP, Hinds D, Risch N. A full genome search in multiple sclerosis. Nat Genet. 1996 Aug; 13(4):472-6.
        View in: PubMed
      167. Sadovnick AD, Ebers GC, Dyment DA, Risch NJ. Evidence for genetic basis of multiple sclerosis. The Canadian Collaborative Study Group. Lancet. 1996 Jun 22; 347(9017):1728-30.
        View in: PubMed
      168. Hanis CL, Boerwinkle E, Chakraborty R, Ellsworth DL, Concannon P, Stirling B, Morrison VA, Wapelhorst B, Spielman RS, Gogolin-Ewens KJ, Shepard JM, Williams SR, Risch N, Hinds D, Iwasaki N, Ogata M, Omori Y, Petzold C, Rietzch H, Schröder HE, Schulze J, Cox NJ, Menzel S, Boriraj VV, Chen X, Lim LR, Lindner T, Mereu LE, Wang YQ, Xiang K, Yamagata K, Yang Y, Bell GI. A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2. Nat Genet. 1996 Jun; 13(2):161-6.
        View in: PubMed
      169. Claus EB, Schildkraut JM, Thompson WD, Risch NJ. The genetic attributable risk of breast and ovarian cancer. Cancer. 1996 Jun 1; 77(11):2318-24.
        View in: PubMed
      170. Ottman R, Annegers JF, Risch N, Hauser WA, Susser M. Relations of genetic and environmental factors in the etiology of epilepsy. Ann Neurol. 1996 Apr; 39(4):442-9.
        View in: PubMed
      171. Risch NJ, Zhang H. Mapping quantitative trait loci with extreme discordant sib pairs: sampling considerations. Am J Hum Genet. 1996 Apr; 58(4):836-43.
        View in: PubMed
      172. Ottman R, Lee JH, Risch N, Hauser WA, Susser M. Clinical indicators of genetic susceptibility to epilepsy. Epilepsia. 1996 Apr; 37(4):353-61.
        View in: PubMed
      173. Risch N, Botstein D. A manic depressive history. Nat Genet. 1996 Apr; 12(4):351-3.
        View in: PubMed
      174. Hauser ER, Boehnke M, Guo SW, Risch N. Affected-sib-pair interval mapping and exclusion for complex genetic traits: sampling considerations. Genet Epidemiol. 1996; 13(2):117-37.
        View in: PubMed
      175. Wildenauer DB, Hallmayer J, Schwab SG, Albus M, Eckstein GN, Zill P, Hönig S, Strauss M, Borrmann M, Lichtermann D, Ebstein RP, Lerer B, Risch N, Maier W. Searching for susceptibility genes in schizophrenia by genetic linkage analysis. Cold Spring Harb Symp Quant Biol. 1996; 61:845-50.
        View in: PubMed
      176. Schwab SG, Albus M, Hallmayer J, Hönig S, Borrmann M, Lichtermann D, Ebstein RP, Ackenheil M, Lerer B, Risch N, et al. Evaluation of a susceptibility gene for schizophrenia on chromosome 6p by multipoint affected sib-pair linkage analysis. Nat Genet. 1995 Nov; 11(3):325-7.
        View in: PubMed
      177. Devlin B, Risch N. A comparison of linkage disequilibrium measures for fine-scale mapping. Genomics. 1995 Sep 20; 29(2):311-22.
        View in: PubMed
      178. Ebers GC, Sadovnick AD, Risch NJ. A genetic basis for familial aggregation in multiple sclerosis. Canadian Collaborative Study Group. Nature. 1995 Sep 14; 377(6545):150-1.
        View in: PubMed
      179. Risch N, Zhang H. Extreme discordant sib pairs for mapping quantitative trait loci in humans. Science. 1995 Jun 16; 268(5217):1584-9.
        View in: PubMed
      180. Rowe RE, Wapelhorst B, Bell GI, Risch N, Spielman RS, Concannon P. Linkage and association between insulin-dependent diabetes mellitus (IDDM) susceptibility and markers near the glucokinase gene on chromosome 7. Nat Genet. 1995 Jun; 10(2):240-2.
        View in: PubMed
      181. Ottman R, Risch N, Hauser WA, Pedley TA, Lee JH, Barker-Cummings C, Lustenberger A, Nagle KJ, Lee KS, Scheuer ML, et al. Localization of a gene for partial epilepsy to chromosome 10q. Nat Genet. 1995 May; 10(1):56-60.
        View in: PubMed
      182. Risch N, de Leon D, Ozelius L, Kramer P, Almasy L, Singer B, Fahn S, Breakefield X, Bressman S. Genetic analysis of idiopathic torsion dystonia in Ashkenazi Jews and their recent descent from a small founder population. Nat Genet. 1995 Feb; 9(2):152-9.
        View in: PubMed
      183. Ottman R, Lee JH, Hauser WA, Risch N. Birth cohort and familial risk of epilepsy: the effect of diminished recall in studies of lifetime prevalence. Am J Epidemiol. 1995 Feb 1; 141(3):235-41.
        View in: PubMed
      184. Wapelhorst B, Bell GI, Risch N, Spielman RS, Concannon P. Linkage and association studies in insulin-dependent diabetes with a new dinucleotide repeat polymorphism at the GAD65 locus. Autoimmunity. 1995; 21(2):127-30.
        View in: PubMed
      185. Almasy L, Tierney C, Risch N. Use of sibling risk ratios and components of genetic variance in the characterization of a simulated oligogenic disease. Genet Epidemiol. 1995; 12(6):565-70.
        View in: PubMed
      186. Bressman SB, de Leon D, Kramer PL, Ozelius LJ, Brin MF, Greene PE, Fahn S, Breakefield XO, Risch NJ. Dystonia in Ashkenazi Jews: clinical characterization of a founder mutation. Ann Neurol. 1994 Nov; 36(5):771-7.
        View in: PubMed
      187. Corder EH, Saunders AM, Risch NJ, Strittmatter WJ, Schmechel DE, Gaskell PC, Rimmler JB, Locke PA, Conneally PM, Schmader KE, et al. Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nat Genet. 1994 Jun; 7(2):180-4.
        View in: PubMed
      188. Giuffra LA, Risch N. Diminished recall and the cohort effect of major depression: a simulation study. Psychol Med. 1994 May; 24(2):375-83.
        View in: PubMed
      189. Marenberg ME, Risch N, Berkman LF, Floderus B, de Faire U. Genetic susceptibility to death from coronary heart disease in a study of twins. N Engl J Med. 1994 Apr 14; 330(15):1041-6.
        View in: PubMed
      190. Merikangas KR, Risch NJ, Weissman MM. Comorbidity and co-transmission of alcoholism, anxiety and depression. Psychol Med. 1994 Feb; 24(1):69-80.
        View in: PubMed
      191. Claus EB, Risch N, Thompson WD. Autosomal dominant inheritance of early-onset breast cancer. Implications for risk prediction. Cancer. 1994 Feb 1; 73(3):643-51.
        View in: PubMed
      192. Tierney C, Merikangas KR, Risch N. Feasibility of half-sibling designs for detecting a genetic component to a disease. Genet Epidemiol. 1994; 11(6):523-38.
        View in: PubMed
      193. Devlin B, Risch N, Roeder K. Comments on the statistical aspects of the NRC's report on DNA typing. J Forensic Sci. 1994 Jan; 39(1):28-40.
        View in: PubMed
      194. Risch N, Squires-Wheeler E, Keats BJ. Male sexual orientation and genetic evidence. Science. 1993 Dec 24; 262(5142):2063-5.
        View in: PubMed
      195. Nygaard TG, Wilhelmsen KC, Risch NJ, Brown DL, Trugman JM, Gilliam TC, Fahn S, Weeks DE. Linkage mapping of dopa-responsive dystonia (DRD) to chromosome 14q. Nat Genet. 1993 Dec; 5(4):386-91.
        View in: PubMed
      196. Devlin B, Krontiris T, Risch N. Population genetics of the HRAS1 minisatellite locus. Am J Hum Genet. 1993 Dec; 53(6):1298-305.
        View in: PubMed
      197. Mitchell LE, Risch N. The genetics of infantile hypertrophic pyloric stenosis. A reanalysis. Am J Dis Child. 1993 Nov; 147(11):1203-11.
        View in: PubMed
      198. Claus EB, Risch N, Thompson WD. The calculation of breast cancer risk for women with a first degree family history of ovarian cancer. Breast Cancer Res Treat. 1993 Nov; 28(2):115-20.
        View in: PubMed
      199. Risch N, Ghosh S, Todd JA. Statistical evaluation of multiple-locus linkage data in experimental species and its relevance to human studies: application to nonobese diabetic (NOD) mouse and human insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet. 1993 Sep; 53(3):702-14.
        View in: PubMed
      200. Krontiris TG, Devlin B, Karp DD, Robert NJ, Risch N. An association between the risk of cancer and mutations in the HRAS1 minisatellite locus. N Engl J Med. 1993 Aug 19; 329(8):517-23.
        View in: PubMed
      201. Devlin B, Risch N. Physical properties of VNTR data, and their impact on a test of allelic independence. Am J Hum Genet. 1993 Aug; 53(2):324-9.
        View in: PubMed
      202. Devlin B, Risch N, Roeder K. NRC report on DNA typing. Science. 1993 May 21; 260(5111):1057-9.
        View in: PubMed
      203. Mitchell LE, Risch N. Correlates of genetic risk for non-syndromic cleft lip with or without cleft palate. Clin Genet. 1993 May; 43(5):255-60.
        View in: PubMed
      204. Gelernter J, Goldman D, Risch N. The A1 allele at the D2 dopamine receptor gene and alcoholism. A reappraisal. JAMA. 1993 Apr 7; 269(13):1673-7.
        View in: PubMed
      205. Devlin B, Risch N, Roeder K. Statistical evaluation of DNA fingerprinting: a critique of the NRC's report. Science. 1993 Feb 5; 259(5096):748-9, 837.
        View in: PubMed
      206. Claus EB, Risch N, Thompson WD, Carter D. Relationship between breast histopathology and family history of breast cancer. Cancer. 1993 Jan 1; 71(1):147-53.
        View in: PubMed
      207. Baron M, Freimer NF, Risch N, Lerer B, Alexander JR, Straub RE, Asokan S, Das K, Peterson A, Amos J, et al. Diminished support for linkage between manic depressive illness and X-chromosome markers in three Israeli pedigrees. Nat Genet. 1993 Jan; 3(1):49-55.
        View in: PubMed
      208. Risch N, Merikangas KR. Linkage studies of psychiatric disorders. Eur Arch Psychiatry Clin Neurosci. 1993; 243(3-4):143-9.
        View in: PubMed
      209. Bernstein JL, Thompson WD, Risch N, Holford TR. The genetic epidemiology of second primary breast cancer. Am J Epidemiol. 1992 Oct 15; 136(8):937-48.
        View in: PubMed
      210. Bernstein JL, Thompson WD, Risch N, Holford TR. Risk factors predicting the incidence of second primary breast cancer among women diagnosed with a first primary breast cancer. Am J Epidemiol. 1992 Oct 15; 136(8):925-36.
        View in: PubMed
      211. Devlin B, Risch N. A note on Hardy-Weinberg equilibrium of VNTR data by using the Federal Bureau of Investigation's fixed-bin method. Am J Hum Genet. 1992 Sep; 51(3):549-53.
        View in: PubMed
      212. Risch N. Corrections to "Linkage strategies for genetically complex traits. III. The effect of marker polymorphism on analysis of affected relative pairs". Am J Hum Genet. 1992 Sep; 51(3):673-5.
        View in: PubMed
      213. Devlin B, Risch N. Ethnic differentiation at VNTR loci, with special reference to forensic applications. Am J Hum Genet. 1992 Sep; 51(3):534-48.
        View in: PubMed
      214. Mitchell LE, Risch N. Mode of inheritance of nonsyndromic cleft lip with or without cleft palate: a reanalysis. Am J Hum Genet. 1992 Aug; 51(2):323-32.
        View in: PubMed
      215. Ozelius LJ, Kramer PL, de Leon D, Risch N, Bressman SB, Schuback DE, Brin MF, Kwiatkowski DJ, Burke RE, Gusella JF, et al. Strong allelic association between the torsion dystonia gene (DYT1) andloci on chromosome 9q34 in Ashkenazi Jews. Am J Hum Genet. 1992 Mar; 50(3):619-28.
        View in: PubMed
      216. Risch N. Genetic linkage: interpreting lod scores. Science. 1992 Feb 14; 255(5046):803-4.
        View in: PubMed
      217. Risch NJ, Devlin B. On the probability of matching DNA fingerprints. Science. 1992 Feb 7; 255(5045):717-20.
        View in: PubMed
      218. Risch N, Giuffra L. Model misspecification and multipoint linkage analysis. Hum Hered. 1992; 42(1):77-92.
        View in: PubMed
      219. Claus EB, Giuffra L, Rogers J, Risch N. Genetic relationship between nevus count or nevus density and cutaneous malignant melanoma. Cytogenet Cell Genet. 1992; 59(2-3):188-90.
        View in: PubMed
      220. Risch N, Sherman S. Genetic Analysis Workshop 7: summary of the melanoma workshop. Cytogenet Cell Genet. 1992; 59(2-3):148-58.
        View in: PubMed
      221. Gelernter J, O'Malley S, Risch N, Kranzler HR, Krystal J, Merikangas K, Kennedy JL, Kidd KK. No association between an allele at the D2 dopamine receptor gene (DRD2) and alcoholism. JAMA. 1991 Oct 2; 266(13):1801-7.
        View in: PubMed
      222. Cupples LA, Risch N, Farrer LA, Myers RH. Estimation of morbid risk and age at onset with missing information. Am J Hum Genet. 1991 Jul; 49(1):76-87.
        View in: PubMed
      223. Risch N. A note on multiple testing procedures in linkage analysis. Am J Hum Genet. 1991 Jun; 48(6):1058-64.
        View in: PubMed
      224. Risch N. Developments in gene mapping with linkage methods. Curr Opin Genet Dev. 1991 Jun; 1(1):93-8.
        View in: PubMed
      225. Devlin B, Risch N, Roeder K. Estimation of allele frequencies for VNTR loci. Am J Hum Genet. 1991 Apr; 48(4):662-76.
        View in: PubMed
      226. Claus EB, Risch N, Thompson WD. Genetic analysis of breast cancer in the cancer and steroid hormone study. Am J Hum Genet. 1991 Feb; 48(2):232-42.
        View in: PubMed
      227. Devlin B, Risch N, Roeder K. No excess of homozygosity at loci used for DNA fingerprinting. Science. 1990 Sep 21; 249(4975):1416-20.
        View in: PubMed
      228. Baron M, Hamburger R, Sandkuyl LA, Risch N, Mandel B, Endicott J, Belmaker RH, Ott J. The impact of phenotypic variation on genetic analysis: application to X-linkage in manic-depressive illness. Acta Psychiatr Scand. 1990 Sep; 82(3):196-203.
        View in: PubMed
      229. Claus EB, Risch NJ, Thompson WD. Age at onset as an indicator of familial risk of breast cancer. Am J Epidemiol. 1990 Jun; 131(6):961-72.
        View in: PubMed
      230. Claus EB, Risch NJ, Thompson WD. Using age of onset to distinguish between subforms of breast cancer. Ann Hum Genet. 1990 May; 54(Pt 2):169-77.
        View in: PubMed
      231. Risch NJ, Bressman SB, deLeon D, Brin MF, Burke RE, Greene PE, Shale H, Claus EB, Cupples LA, Fahn S. Segregation analysis of idiopathic torsion dystonia in Ashkenazi Jews suggests autosomal dominant inheritance. Am J Hum Genet. 1990 Mar; 46(3):533-8.
        View in: PubMed
      232. Kramer PL, de Leon D, Ozelius L, Risch N, Bressman SB, Brin MF, Schuback DE, Burke RE, Kwiatkowski DJ, Shale H, et al. Dystonia gene in Ashkenazi Jewish population is located on chromosome 9q32-34. Ann Neurol. 1990 Feb; 27(2):114-20.
        View in: PubMed
      233. Risch N. Linkage strategies for genetically complex traits. I. Multilocus models. Am J Hum Genet. 1990 Feb; 46(2):222-8.
        View in: PubMed
      234. Risch N. Linkage strategies for genetically complex traits. III. The effect of marker polymorphism on analysis of affected relative pairs. Am J Hum Genet. 1990 Feb; 46(2):242-53.
        View in: PubMed
      235. Risch N. Linkage strategies for genetically complex traits. II. The power of affected relative pairs. Am J Hum Genet. 1990 Feb; 46(2):229-41.
        View in: PubMed
      236. Risch N. Genetic linkage and complex diseases, with special reference to psychiatric disorders. Genet Epidemiol. 1990; 7(1):3-16; discussion 17-45.
        View in: PubMed
      237. Bressman SB, de Leon D, Brin MF, Risch N, Burke RE, Greene PE, Shale H, Fahn S. Idiopathic dystonia among Ashkenazi Jews: evidence for autosomal dominant inheritance. Ann Neurol. 1989 Nov; 26(5):612-20.
        View in: PubMed
      238. Schildkraut JM, Risch N, Thompson WD. Evaluating genetic association among ovarian, breast, and endometrial cancer: evidence for a breast/ovarian cancer relationship. Am J Hum Genet. 1989 Oct; 45(4):521-9.
        View in: PubMed
      239. Ozelius L, Kramer PL, Moskowitz CB, Kwiatkowski DJ, Brin MF, Bressman SB, Schuback DE, Falk CT, Risch N, de Leon D, et al. Human gene for torsion dystonia located on chromosome 9q32-q34. Neuron. 1989 May; 2(5):1427-34.
        View in: PubMed
      240. Risch N, Claus E, Giuffra L. Linkage and mode of inheritance in complex traits. Prog Clin Biol Res. 1989; 329:183-8.
        View in: PubMed
      241. Rice J, Risch N. Genetic analysis of the affective disorders: summary of GAW5. Genet Epidemiol. 1989; 6(1):161-77.
        View in: PubMed
      242. Risch N. Genetics of IDDM: evidence for complex inheritance with HLA. Genet Epidemiol. 1989; 6(1):143-8.
        View in: PubMed
      243. Risch N. Linkage detection tests under heterogeneity. Genet Epidemiol. 1989; 6(4):473-80.
        View in: PubMed
      244. Risch N. Description of X-linkage pedigrees. Genet Epidemiol. 1989; 6(1):187-9.
        View in: PubMed
      245. Cornblatt BA, Risch NJ, Faris G, Friedman D, Erlenmeyer-Kimling L. The Continuous Performance Test, identical pairs version (CPT-IP): I. New findings about sustained attention in normal families. Psychiatry Res. 1988 Nov; 26(2):223-38.
        View in: PubMed
      246. Risch N. A new statistical test for linkage heterogeneity. Am J Hum Genet. 1988 Feb; 42(2):353-64.
        View in: PubMed
      247. Bressman SB, de Leon D, Brin MF, Risch N, Shale H, Burke RE, Greene PE, Fahn S. Inheritance of idiopathic torsion dystonia among Ashkenazi Jews. Adv Neurol. 1988; 50:45-56.
        View in: PubMed
      248. Merikangas KR, Risch NJ, Merikangas JR, Weissman MM, Kidd KK. Migraine and depression: association and familial transmission. J Psychiatr Res. 1988; 22(2):119-29.
        View in: PubMed
      249. Risch N, Reich EW, Wishnick MM, McCarthy JG. Spontaneous mutation and parental age in humans. Am J Hum Genet. 1987 Aug; 41(2):218-48.
        View in: PubMed
      250. Baron M, Risch N, Hamburger R, Mandel B, Kushner S, Newman M, Drumer D, Belmaker RH. Genetic linkage between X-chromosome markers and bipolar affective illness. Nature. 1987 Mar 19-25; 326(6110):289-92.
        View in: PubMed
      251. Baron M, Risch N. The spectrum concept of schizophrenia: evidence for a genetic-environmental continuum. J Psychiatr Res. 1987; 21(3):257-67.
        View in: PubMed
      252. Risch N. Assessing the role of HLA-linked and unlinked determinants of disease. Am J Hum Genet. 1987 Jan; 40(1):1-14.
        View in: PubMed
      253. Risch N, Stein Z, Kline J, Warburton D. The relationship between maternal age and chromosome size in autosomal trisomy. Am J Hum Genet. 1986 Jul; 39(1):68-78.
        View in: PubMed
      254. Risch N, Baron M, Mendlewicz J. Assessing the role of X-linked inheritance in bipolar-related major affective disorder. J Psychiatr Res. 1986; 20(4):275-88.
        View in: PubMed
      255. Risch N. Genetic analysis workshop IV: summary of the multiple sclerosis workshop. Genet Epidemiol Suppl. 1986; 1:371-80.
        View in: PubMed
      256. Risch N. Conditional linkage analysis of multiple sclerosis data. Genet Epidemiol Suppl. 1986; 1:387-92.
        View in: PubMed
      257. Baron M, Risch N, Levitt M, Gruen R. Genetic analysis of plasma amine oxidase activity in schizophrenia. Psychiatry Res. 1985 Jun; 15(2):121-32.
        View in: PubMed
      258. Risch N, Baron M. Segregation analysis of schizophrenia and related disorders. Am J Hum Genet. 1984 Sep; 36(5):1039-59.
        View in: PubMed
      259. Risch N. Segregation analysis incorporating linkage markers. I. Single-locus models with an application to type I diabetes. Am J Hum Genet. 1984 Mar; 36(2):363-86.
        View in: PubMed
      260. Risch N. Genetic Analysis Workshop II: multiple-locus segregation analysis incorporating linkage markers. Genet Epidemiol. 1984; 1(2):207-11.
        View in: PubMed
      261. Risch N. The effects of reduced fertility, method of ascertainment, and a second unlinked locus on affected sib-pair marker allele sharing. Am J Med Genet. 1983 Oct; 16(2):243-59.
        View in: PubMed
      262. Risch N. Estimating morbidity risks in relatives: the effect of reduced fertility. Behav Genet. 1983 Sep; 13(5):441-51.
        View in: PubMed
      263. Risch N. A general model for disease-marker association. Ann Hum Genet. 1983 Jul; 47(Pt 3):245-52.
        View in: PubMed
      264. Risch N, Baron M. X-linkage and genetic heterogeneity in bipolar-related major affective illness: reanalysis of linkage data. Ann Hum Genet. 1982 May; 46(Pt 2):153-66.
        View in: PubMed
      265. Baron M, Risch N. X-linkage in affective and schizoaffective disorders: genetic and diagnostic implications. Neuropsychobiology. 1982; 8(6):304-11.
        View in: PubMed
      266. Baron M, Rainer JD, Risch N. X-linkage in bipolar affective illness. Perspectives on genetic heterogeneity, pedigree analysis and the X-chromosome map. J Affect Disord. 1981 Jun; 3(2):141-57.
        View in: PubMed
      267. Risch N, Lange K. Application of a recombination model in calculating the variance of sib pair genetic identity. Ann Hum Genet. 1979 Oct; 43(2):177-86.
        View in: PubMed
      268. Risch N, Lange K. An alternative model of recombination and interference. Ann Hum Genet. 1979 Jul; 43(1):61-70.
        View in: PubMed
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