Nilotpal Roy, PhD

TitlePostdoctoral Scholar
SchoolUCSF School of Medicine
DepartmentDiabetes Center
Address513 Parnassus Ave
San Francisco CA 94143
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    Collapse Biography 
    Collapse education and training
    University of CalcuttaB.Sc2004Dept of Zoology
    University of CalcuttaM.Sc2006Dept of Biochemistry
    University of IlinoisPhD2012Dept of Biochemistry and Molecular genetics
    Collapse Awards and Honors
    University of Illinois2010 - 2011Deans' Scholar Award
    American Association of Cancer Research2014 - 2015Basic Cancer Research Fellowship
    Sandler Foundation2015 - 2016UCSF Program for Breakthrough Biomedical Research (PBBR) Postdoctoral Independent Research Award

    Collapse Bibliographic 
    Collapse Selected Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Roy N, Takeuchi KK, Ruggeri JM, Bailey P, Chang D, Li J, Leonhardt L, Puri S, Hoffman MT, Gao S, Halbrook CJ, Song Y, Ljungman M, Malik S, Wright CV, Dawson DW, Biankin AV, Hebrok M, Crawford HC. PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance. Genes Dev. 2016 Dec 15; 30(24):2669-2683. PMID: 28087712.
      View in: PubMed
    2. Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, Kalluri R, Iacobuzio-Donahue CA, Wood LD, Hebrok M, Hansen K, Moses HL, Weaver VM. Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nat Med. 2016 May; 22(5):497-505. PMID: 27089513.
      View in: PubMed
    3. Hendley AM, Wang YJ, Polireddy K, Alsina J, Ahmed I, Lafaro KJ, Zhang H, Roy N, Savidge SG, Cao Y, Hebrok M, Maitra A, Reynolds A, Goggins MG, Younes M, Iacobuzio-Donahue CA, Leach SD, Bailey J. p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia. Cancer Res. 2016 Jun 1; 76(11):3351-63. PMID: 27032419.
      View in: PubMed
    4. Roy N, Hebrok M. Regulation of Cellular Identity in Cancer. Dev Cell. 2015 Dec 21; 35(6):674-84. PMID: 26702828.
      View in: PubMed
    5. Malik S, Villanova L, Tanaka S, Aonuma M, Roy N, Berber E, Pollack JR, Michishita-Kioi E, Chua KF. SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumors. Sci Rep. 2015; 5:9841. PMID: 25923013; PMCID: PMC4413894.
    6. Roy N, Malik S, Villanueva KE, Urano A, Lu X, Von Figura G, Seeley ES, Dawson DW, Collisson EA, Hebrok M. Brg1 promotes both tumor-suppressive and oncogenic activities at distinct stages of pancreatic cancer formation. Genes Dev. 2015 Mar 15; 29(6):658-71. PMID: 25792600; PMCID: PMC4378197.
    7. von Figura G, Fukuda A, Roy N, Liku ME, Morris Iv JP, Kim GE, Russ HA, Firpo MA, Mulvihill SJ, Dawson DW, Ferrer J, Mueller WF, Busch A, Hertel KJ, Hebrok M. The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma. Nat Cell Biol. 2014 Mar; 16(3):255-67. PMID: 24561622.
      View in: PubMed
    8. Roy N, Bommi PV, Bhat UG, Bhattacharjee S, Elangovan I, Li J, Patra KC, Kopanja D, Blunier A, Benya R, Bagchi S, Raychaudhuri P. DDB2 suppresses epithelial-to-mesenchymal transition in colon cancer. Cancer Res. 2013 Jun 15; 73(12):3771-82. PMID: 23610444; PMCID: PMC3686976.
    9. Roy N, Elangovan I, Kopanja D, Bagchi S, Raychaudhuri P. Tumor regression by phenethyl isothiocyanate involves DDB2. Cancer Biol Ther. 2013 Feb; 14(2):108-16. PMID: 23114715; PMCID: PMC3571992.
    10. Roy N, Bagchi S, Raychaudhuri P. Damaged DNA binding protein 2 in reactive oxygen species (ROS) regulation and premature senescence. Int J Mol Sci. 2012; 13(9):11012-26. PMID: 23109835; PMCID: PMC3472727.
    11. Stoyanova T, Roy N, Bhattacharjee S, Kopanja D, Valli T, Bagchi S, Raychaudhuri P. p21 cooperates with DDB2 protein in suppression of ultraviolet ray-induced skin malignancies. J Biol Chem. 2012 Jan 27; 287(5):3019-28. PMID: 22167187; PMCID: PMC3270959.
    12. Kopanja D, Roy N, Stoyanova T, Hess RA, Bagchi S, Raychaudhuri P. Cul4A is essential for spermatogenesis and male fertility. Dev Biol. 2011 Apr 15; 352(2):278-87. PMID: 21291880; PMCID: PMC3065526.
    13. Roy N, Stoyanova T, Dominguez-Brauer C, Park HJ, Bagchi S, Raychaudhuri P. DDB2, an essential mediator of premature senescence. Mol Cell Biol. 2010 Jun; 30(11):2681-92. PMID: 20351176; PMCID: PMC2876515.
    14. Stoyanova T, Roy N, Kopanja D, Raychaudhuri P, Bagchi S. DDB2 (damaged-DNA binding protein 2) in nucleotide excision repair and DNA damage response. Cell Cycle. 2009 Dec 15; 8(24):4067-71. PMID: 19923893; PMCID: PMC3107032.
    15. Stoyanova T, Roy N, Kopanja D, Bagchi S, Raychaudhuri P. DDB2 decides cell fate following DNA damage. Proc Natl Acad Sci U S A. 2009 Jun 30; 106(26):10690-5. PMID: 19541625; PMCID: PMC2705559.
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