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    Nisha Parikh, MD

    TitleAssistant Professor
    SchoolUCSF School of Medicine
    Address555 Mission Bay Blvd South
    San Francisco CA 94158
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      Clinical Interests: Dr. Parikh is a noninvasive cardiologist and echocardiographer. She completed internal medicine training at Tufts-New England Medical Center and cardiovascular training at Harvard-Beth Israel Deaconess Medical Center. Her primary clinical interests are in primary and secondary prevention and cardiovascular diseases in women including heart disease in pregnancy.

      Research Interests: Dr. Parikh is a cardiovascular epidemiologist and population scientist. She has an MPH in epidemiology and biostatistics from the U.C. Berkeley School of Public Health and did her post-doctoral research fellowship at the Framingham Heart Study. In her NIH/NRSA supported work, she demonstrated in the Multi Ethnic Study of Atherosclerosis that the hemodynamic changes of pregnancy may not revert back to normal, may be cumulative across successive pregnancies, and can lead to left ventricular remodeling on cardiac MRI in mid-life. Supported by grants from both the American Heart Association and the NIH/National Heart Lung and Blood Institute, she is currently working to develop risk stratification tools that can be employed as an 'early window' into later cardiovascular disease risk in women. She is utilizing data from the Women's Health Initiative Observational Study and the Swedish Population Registers to develop and validate these risk tools. She is also interested in discovering specific mechanisms and pathways that link adverse pregnancy outcomes such as preeclampsia and preterm delivery with subclinical and overt cardiovascular disease in women via metabolomic and epigenetic techniques.

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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Parikh NI, Jeppson RP, Berger JS, Eaton CB, Kroenke CH, LaBlanc ES, Lewis CE, Loucks EB, Parker DR, Rillamas-Sun E, Ryckman KK, Waring ME, Schenken RS, Johnson KC, Edstedt-Bonamy AK, Allison MA, Howard BV, et al. Reproductive Risk Factors and Coronary Heart Disease in the Women's Health Initiative Observational Study. Circulation. 2016 Apr 19. PMID: 27143682.
        View in: PubMed
      2. Chow D, Young R, Valcour N, Kronmal RA, Lum CJ, Parikh NI, Tracy RP, Budoff M, Shikuma CM. HIV and coronary artery calcium score: comparison of the Hawaii Aging with HIV Cardiovascular Study and Multi-Ethnic Study of Atherosclerosis (MESA) cohorts. HIV Clin Trials. 2015 Aug; 16(4):130-8. PMID: 26038953.
        View in: PubMed
      3. Sanghavi M, Kulinski J, Ayers CR, Nelson D, Stewart R, Parikh N, de Lemos JA, Khera A, et al. Association between number of live births and markers of subclinical atherosclerosis: The Dallas Heart Study. Eur J Prev Cardiol. 2015 Feb 17. PMID: 25691547.
        View in: PubMed
      4. Munger AM, Chow DC, Playford MP, Parikh NI, Gangcuangco LM, Nakamoto BK, Kallianpur KJ, Ndhlovu LC, Shikuma CM, Mehta NN. Characterization of Lipid Composition and High-Density Lipoprotein Function in HIV-Infected Individuals on Stable Antiretroviral Regimens. AIDS Res Hum Retroviruses. 2015 Feb; 31(2):221-8. PMID: 25416403.
        View in: PubMed
      5. Parikh NI, Gerschenson M, Bennett K, Gangcuangco LM, Lopez MS, Mehta NN, Playford MP, Nakamoto BK, Seto TB, Chow DC, Shikuma CM. Lipoprotein concentration, particle number, size and cholesterol efflux capacity are associated with mitochondrial oxidative stress and function in an HIV positive cohort. Atherosclerosis. 2015 Mar; 239(1):50-4. PMID: 25574857.
        View in: PubMed
      6. Parker DR, Lu B, Sands-Lincoln M, Kroenke CH, Lee CC, O'Sullivan M, Park HL, Parikh N, Schenken RS, Eaton CB. Risk of cardiovascular disease among postmenopausal women with prior pregnancy loss: the women's health initiative. Ann Fam Med. 2014 Jul; 12(4):302-9. PMID: 25024237; PMCID: PMC4096466 [Available on 01/01/15].
      7. Ryckman KK, Rillamas-Sun E, Spracklen CN, Wallace RB, Garcia L, Tylavsky FA, Howard BV, Liu S, Song Y, LeBlanc ES, White MV, Parikh NI, Robinson JG. Ethnic differences in the relationship between birth weight and type 2 diabetes mellitus in postmenopausal women. Diabetes Metab. 2014 Nov; 40(5):379-85. PMID: 24751988; PMCID: PMC4638122.
      8. Shikuma CM, Chow DC, Gangcuangco LM, Zhang G, Keating SM, Norris PJ, Seto TB, Parikh N, Kallianpur KJ, Nakamoto BK, Nagamine LS, Ndhlovu LC, Barbour JD. Monocytes expand with immune dysregulation and is associated with insulin resistance in older individuals with chronic HIV. PLoS One. 2014; 9(2):e90330. PMID: 24587328; PMCID: PMC3937368.
      9. Li D, Le Pape MA, Parikh NI, Chen WX, Dye TD. Assessing differential expression in two-color microarrays: a resampling-based empirical Bayes approach. PLoS One. 2013; 8(11):e80099. PMID: 24312198; PMCID: PMC3842292.
      10. Barbour JD, Jalbert EC, Chow DC, Gangcuangco LM, Norris PJ, Keating SM, Heitman J, Nagamine L, Seto T, Ndhlovu LC, Nakamoto BK, Hodis HN, Parikh NI, Shikuma CM. Reduced CD14 expression on classical monocytes and vascular endothelial adhesion markers independently associate with carotid artery intima media thickness in chronically HIV-1 infected adults on virologically suppressive anti-retroviral therapy. Atherosclerosis. 2014 Jan; 232(1):52-8. PMID: 24401216; PMCID: PMC3919042 [Available on 01/01/15].
      11. Nakamoto BK, Shikuma CM, Ogata-Arakaki D, Umaki T, Neuwelt EA, Shiramizu BT, Chow DC, Parikh NI, Kallianpur KJ, Hamilton BE. Feasibility and potential role of ferumoxytol-enhanced neuroimaging in HIV-associated neurocognitive disorder. J Neurovirol. 2013 Dec; 19(6):601-5. PMID: 24129909; PMCID: PMC3947641 [Available on 12/01/14].
      12. Chua Chiaco JM, Parikh NI, Fergusson DJ. The jugular venous pressure revisited. Cleve Clin J Med. 2013 Oct; 80(10):638-44. PMID: 24085809.
        View in: PubMed
      13. Jalbert E, Crawford TQ, D'Antoni ML, Keating SM, Norris PJ, Nakamoto BK, Seto T, Parikh NI, Shikuma CM, Ndhlovu LC, Barbour JD. IL-1? enriched monocytes mount massive IL-6 responses to common inflammatory triggers among chronically HIV-1 infected adults on stable anti-retroviral therapy at risk for cardiovascular disease. PLoS One. 2013; 8(9):e75500. PMID: 24086545; PMCID: PMC3783392.
      14. Shikuma CM, Barbour JD, Ndhlovu LC, Keating SM, Norris PJ, Budoff M, Parikh N, Seto T, Gangcuangco LM, Ogata-Arakaki D, Chow D. Plasma monocyte chemoattractant protein-1 and tumor necrosis factor-a levels predict the presence of coronary artery calcium in HIV-infected individuals independent of traditional cardiovascular risk factors. AIDS Res Hum Retroviruses. 2014 Feb; 30(2):142-6. PMID: 23984974; PMCID: PMC3910454 [Available on 02/01/15].
      15. Chow D, Nakamoto B, So E, Parikh N, Souza S, Kallianpur K, Shikuma C. Rates of autonomic dysfunction in HIV patients receiving antiretroviral therapy. J Neurovirol. 2013 Oct; 19(5):511-2. PMID: 24018903.
        View in: PubMed
      16. Tongma C, Shikuma CM, Nakamoto BK, Kallianpur KJ, Umaki TM, Barbour JD, Ndhlovu L, Parikh NI, Chow DC. Albuminuria as a marker of cardiovascular risk in HIV-infected individuals receiving stable antiretroviral therapy. Hawaii J Med Public Health. 2013 Sep; 72(9 Suppl 4):34-8. PMID: 24052917; PMCID: PMC3764546.
      17. Won S, Hong RA, Shohet RV, Seto TB, Parikh NI. Methamphetamine-associated cardiomyopathy. Clin Cardiol. 2013 Dec; 36(12):737-42. PMID: 24037954.
        View in: PubMed
      18. Ryckman KK, Borowski KS, Parikh NI, Saftlas AF, et al. Pregnancy Complications and the Risk of Metabolic Syndrome for the Offspring. Curr Cardiovasc Risk Rep. 2013 Jun; 7(3):217-223. PMID: 23997844.
        View in: PubMed
      19. Edstedt-Bonamy A-K, Parikh NI. . Current Cardiovascular Risk Reports. Eds. Robinson JF and Levy D. Predicting Women’s Future Cardiovascular Health from Pregnancy Complications. 2013; 7(3):173-82.
      20. Lin C, Grandinetti A, Shikuma C, Souza S, Parikh N, Nakamoto B, Kallianpur KJ, Chow D. The effects of extended release niacin on lipoprotein sub-particle concentrations in HIV-infected patients. Hawaii J Med Public Health. 2013 Apr; 72(4):123-7. PMID: 23795312; PMCID: PMC3689507.
      21. Carty CL, Spencer KL, Setiawan VW, Fernandez-Rhodes L, Malinowski J, Buyske S, Young A, Jorgensen NW, Cheng I, Carlson CS, Brown-Gentry K, Goodloe R, Park A, Parikh NI, Henderson B, Le Marchand L, Wactawski-Wende J, Fornage M, Matise TC, Hindorff LA, Arnold AM, Haiman CA, Franceschini N, Peters U, Crawford DC. Replication of genetic loci for ages at menarche and menopause in the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) study. Hum Reprod. 2013 Jun; 28(6):1695-706. PMID: 23508249; PMCID: PMC3657124.
      22. Parikh NI, Honeycutt EF, Roe MT, Neely M, Rosenthal EJ, Mittleman MA, Carrozza JP, Ho KK. Left and codominant coronary artery circulations are associated with higher in-hospital mortality among patients undergoing percutaneous coronary intervention for acute coronary syndromes: report From the National Cardiovascular Database Cath Percutaneous Coronary Intervention (CathPCI) Registry. Circ Cardiovasc Qual Outcomes. 2012 Nov; 5(6):775-82. PMID: 23110791.
        View in: PubMed
      23. Chow D, Kocher M, Shikuma C, Parikh N, Grandinetti A, Nakamoto B, Seto T, Low P. Effects of antiretroviral therapy on autonomic function in early HIV infection: a preliminary report. Int J Med Sci. 2012; 9(5):397-405. PMID: 22859899; PMCID: PMC3410283.
      24. Chow D, Thomas BS, Liang CY, Souza SC, Nakamoto BK, Parikh NI, Shikuma C. Role of the veterans aging cohort study index in assessing total atherosclerotic burden. Clin Infect Dis. 2012 Sep; 55(5):750-1; author reply 751-2. PMID: 22670040; PMCID: PMC3732044.
      25. Parikh NI, Lloyd-Jones DM, Ning H, Ouyang P, Polak JF, Lima JA, Bluemke D, Mittleman MA. Association of number of live births with left ventricular structure and function. The Multi-Ethnic Study of Atherosclerosis (MESA). Am Heart J. 2012 Mar; 163(3):470-6. PMID: 22424019; PMCID: PMC3656723.
      26. Parikh NI, Cnattingius S, Mittleman MA, Ludvigsson JF, Ingelsson E. Subfertility and risk of later life maternal cardiovascular disease. Hum Reprod. 2012 Feb; 27(2):568-75. PMID: 22131387; PMCID: PMC3283089.
      27. Bonamy AK, Parikh NI, Cnattingius S, Ludvigsson JF, Ingelsson E. Birth characteristics and subsequent risks of maternal cardiovascular disease: effects of gestational age and fetal growth. Circulation. 2011 Dec 20; 124(25):2839-46. PMID: 22124377.
        View in: PubMed
      28. Parikh NI. Sex differences in the risk of cardiovascular disease. BMJ. 2011; 343:d5526. PMID: 21896609.
        View in: PubMed
      29. Parikh NI, Cnattingius S, Dickman PW, Mittleman MA, Ludvigsson JF, Ingelsson E. Parity and risk of later-life maternal cardiovascular disease. Am Heart J. 2010 Feb; 159(2):215-221.e6. PMID: 20152219.
        View in: PubMed
      30. Parikh NI, Hwang SJ, Ingelsson E, Benjamin EJ, Fox CS, Vasan RS, Murabito JM. Breastfeeding in infancy and adult cardiovascular disease risk factors. Am J Med. 2009 Jul; 122(7):656-63.e1. PMID: 19559168; PMCID: PMC2704490.
      31. Parikh NI, Keyes MJ, Larson MG, Pou KM, Hamburg NM, Vita JA, O'Donnell CJ, Vasan RS, Mitchell GF, Hoffmann U, Fox CS, Benjamin EJ. Visceral and subcutaneous adiposity and brachial artery vasodilator function. Obesity (Silver Spring). 2009 Nov; 17(11):2054-9. PMID: 19282819; PMCID: PMC3086764.
      32. Parikh NI, Gona P, Larson MG, Fox CS, Benjamin EJ, Murabito JM, O'Donnell CJ, Vasan RS, Levy D. Long-term trends in myocardial infarction incidence and case fatality in the National Heart, Lung, and Blood Institute's Framingham Heart study. Circulation. 2009 Mar 10; 119(9):1203-10. PMID: 19237656; PMCID: PMC2725400.
      33. Velagaleti RS, Pencina MJ, Murabito JM, Wang TJ, Parikh NI, D'Agostino RB, Levy D, Kannel WB, Vasan RS. Long-term trends in the incidence of heart failure after myocardial infarction. Circulation. 2008 Nov 11; 118(20):2057-62. PMID: 18955667; PMCID: PMC2729712.
      34. Parikh NI, Hwang SJ, Yang Q, Larson MG, Guo CY, Robins SJ, Sutherland P, Benjamin EJ, Levy D, Fox CS. Clinical correlates and heritability of cystatin C (from the Framingham Offspring Study). Am J Cardiol. 2008 Nov 1; 102(9):1194-8. PMID: 18940290; PMCID: PMC2709776.
      35. Parikh NI, Hwang SJ, Larson MG, Hoffmann U, Levy D, Meigs JB, O'Donnell CJ, Fox CS. Indexes of kidney function and coronary artery and abdominal aortic calcium (from the Framingham Offspring Study). Am J Cardiol. 2008 Aug 15; 102(4):440-3. PMID: 18678302; PMCID: PMC2709777.
      36. Parikh NI, Hwang SJ, Larson MG, Levy D, Fox CS. Chronic kidney disease as a predictor of cardiovascular disease (from the Framingham Heart Study). Am J Cardiol. 2008 Jul 1; 102(1):47-53. PMID: 18572034; PMCID: PMC2517213.
      37. Foster MC, Hwang SJ, Larson MG, Lichtman JH, Parikh NI, Vasan RS, Levy D, Fox CS. Overweight, obesity, and the development of stage 3 CKD: the Framingham Heart Study. Am J Kidney Dis. 2008 Jul; 52(1):39-48. PMID: 18440684; PMCID: PMC2531220.
      38. Parikh NI, Pencina MJ, Wang TJ, Benjamin EJ, Lanier KJ, Levy D, D'Agostino RB, Kannel WB, Vasan RS. A risk score for predicting near-term incidence of hypertension: the Framingham Heart Study. Ann Intern Med. 2008 Jan 15; 148(2):102-10. PMID: 18195335.
        View in: PubMed
      39. Parikh NI, Vasan RS. Assessing the clinical utility of biomarkers in medicine. Biomark Med. 2007 Oct; 1(3):419-36. PMID: 20477384.
        View in: PubMed
      40. Parikh NI, Gona P, Larson MG, Wang TJ, Newton-Cheh C, Levy D, Benjamin EJ, Kannel WB, Vasan RS. Plasma renin and risk of cardiovascular disease and mortality: the Framingham Heart Study. Eur Heart J. 2007 Nov; 28(21):2644-52. PMID: 17895253.
        View in: PubMed
      41. Parikh NI, Hwang SJ, Larson MG, Cupples LA, Fox CS, Manders ES, Murabito JM, Massaro JM, Hoffmann U, O'Donnell CJ. Parental occurrence of premature cardiovascular disease predicts increased coronary artery and abdominal aortic calcification in the Framingham Offspring and Third Generation cohorts. Circulation. 2007 Sep 25; 116(13):1473-81. PMID: 17785619.
        View in: PubMed
      42. Foster MC, Hwang SJ, Larson MG, Parikh NI, Meigs JB, Vasan RS, Wang TJ, Levy D, Fox CS. Cross-classification of microalbuminuria and reduced glomerular filtration rate: associations between cardiovascular disease risk factors and clinical outcomes. Arch Intern Med. 2007 Jul 9; 167(13):1386-92. PMID: 17620532.
        View in: PubMed
      43. Parikh NI, Pencina MJ, Wang TJ, Lanier KJ, Fox CS, D'Agostino RB, Vasan RS. Increasing trends in incidence of overweight and obesity over 5 decades. Am J Med. 2007 Mar; 120(3):242-50. PMID: 17349447.
        View in: PubMed
      44. Parikh NI, Hwang SJ, Larson MG, Meigs JB, Levy D, Fox CS. Cardiovascular disease risk factors in chronic kidney disease: overall burden and rates of treatment and control. Arch Intern Med. 2006 Sep 25; 166(17):1884-91. PMID: 17000946.
        View in: PubMed
      45. Kuvin J, Parikh N, Salomon R, Tischler A, Daoust P, Arshanskiy Y, Coyner K, Carpino P, Pandian NG, Kimmelstiel C, Foote C, Erban J, Rastegar H. Images in cardiovascular medicine. Primary lymphoma of the heart. Circulation. 2005 Jul 5; 112(1):e5-6. PMID: 15998689.
        View in: PubMed
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