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    Oren Rosenberg, MD, PhD

    TitleAssistant Professor
    SchoolUCSF School of Medicine
    DepartmentMedicine
    Address513 Parnassus Ave
    San Francisco CA 94143
    Phone415-514-0412
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      Collapse Biography 
      Collapse Education and Training
      Yale University School of MedicineMD/PhD2007
      Brigham and Women's HospitalInternship and ResidencyInternal Medicine2009
      University of California, San FranciscoFellowshipInternal Medicine, Division of Infectious Diseases2013

      Collapse Overview 
      Collapse Overview
      I am a physician-scientist who studies and treats infectious diseases. The goal of my laboratory is to discover and exploit molecular vulnerabilities in bacteria in order to design faster, cheaper, less toxic and more effective therapeutics to treat life-threatening infections.


      Collapse ORNG Applications 
      Collapse Websites
      Collapse Awarded Grants
      Collapse Global Health

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Mirrashidi KM, Elwell CA, Verschueren E, Johnson JR, Frando A, Von Dollen J, Rosenberg O, Gulbahce N, Jang G, Johnson T, J├Ąger S, Gopalakrishnan AM, Sherry J, Dunn JD, Olive A, Penn B, Shales M, Cox JS, Starnbach MN, Derre I, Valdivia R, Krogan NJ, Engel J. Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection. Cell Host Microbe. 2015 Jul 8; 18(1):109-21. PMID: 26118995; PMCID: PMC4540348 [Available on 07/08/16].
      2. Rosenberg OS, Dovala D, Li X, Connolly L, Bendebury A, Finer-Moore J, Holton J, Cheng Y, Stroud RM, Cox JS. Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion. Cell. 2015 Apr 23; 161(3):501-12. PMID: 25865481; PMCID: PMC4409929 [Available on 04/23/16].
      3. Lohse MB, Rosenberg OS, Cox JS, Stroud RM, Finer-Moore JS, Johnson AD. Structure of a new DNA-binding domain which regulates pathogenesis in a wide variety of fungi. Proc Natl Acad Sci U S A. 2014 Jul 22; 111(29):10404-10. PMID: 24994900; PMCID: PMC4115540.
      4. Hadjivassiliou H, Rosenberg OS, Guthrie C. The crystal structure of S. cerevisiae Sad1, a catalytically inactive deubiquitinase that is broadly required for pre-mRNA splicing. RNA. 2014 May; 20(5):656-69. PMID: 24681967; PMCID: PMC3988567.
      5. Scharschmidt TC, Amerson EH, Rosenberg OS, Jacobs RA, McCalmont TH, Shinkai K. Immune reconstitution reactions in human immunodeficiency virus-negative patients: report of a case and review of the literature. JAMA Dermatol. 2013 Jan; 149(1):74-8. PMID: 23324760; PMCID: PMC3773570.
      6. Chao LH, Stratton MM, Lee IH, Rosenberg OS, Levitz J, Mandell DJ, Kortemme T, Groves JT, Schulman H, Kuriyan J. A mechanism for tunable autoinhibition in the structure of a human Ca2+/calmodulin- dependent kinase II holoenzyme. Cell. 2011 Sep 2; 146(5):732-45. PMID: 21884935; PMCID: PMC3184253.
      7. Rosenberg OS, Dovey C, Tempesta M, Robbins RA, Finer-Moore JS, Stroud RM, Cox JS. EspR, a key regulator of Mycobacterium tuberculosis virulence, adopts a unique dimeric structure among helix-turn-helix proteins. Proc Natl Acad Sci U S A. 2011 Aug 16; 108(33):13450-5. PMID: 21795602; PMCID: PMC3158157.
      8. Rosenberg OS, Deindl S, Comolli LR, Hoelz A, Downing KH, Nairn AC, Kuriyan J. Oligomerization states of the association domain and the holoenyzme of Ca2+/CaM kinase II. FEBS J. 2006 Feb; 273(4):682-94. PMID: 16441656.
        View in: PubMed
      9. Rosenberg OS, Deindl S, Sung RJ, Nairn AC, Kuriyan J. Structure of the autoinhibited kinase domain of CaMKII and SAXS analysis of the holoenzyme. Cell. 2005 Dec 2; 123(5):849-60. PMID: 16325579.
        View in: PubMed
      10. Terlouw DJ, Nahlen BL, Courval JM, Kariuki SK, Rosenberg OS, Oloo AJ, Kolczak MS, Hawley WA, Lal AA, Kuile FO. Sulfadoxine-pyrimethamine in treatment of malaria in Western Kenya: increasing resistance and underdosing. Antimicrob Agents Chemother. 2003 Sep; 47(9):2929-32. PMID: 12936996; PMCID: PMC182608.
      11. Terlouw DJ, Courval JM, Kolczak MS, Rosenberg OS, Oloo AJ, Kager PA, Lal AA, Nahlen BL, ter Kuile FO. Treatment history and treatment dose are important determinants of sulfadoxine-pyrimethamine efficacy in children with uncomplicated malaria in Western Kenya. J Infect Dis. 2003 Feb 1; 187(3):467-76. PMID: 12552431.
        View in: PubMed
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