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    Patricia Leake, PhD

    TitleProfessor
    SchoolUCSF School of Medicine
    DepartmentOtolaryngology
    Address533 Parnassus Ave, UC Hall
    San Francisco CA 94143
    Phone415-476-5958

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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Leake PA, Plummer JM, Rhoden A, Frankson MA, Gordon-Strachan G, Powell LP, Roberts PO. Colorectal anastomotic leakage at the university hospital of the west indies: an analysis of risk factors. West Indian Med J. 2013 Nov; 62(9):711-5.
        View in: PubMed
      2. McFarlane ME, Plummer JM, Leake PA, Powell L, Chand V, Chung S, Tulloch K. Dengue fever mimicking acute appendicitis: A case report. Int J Surg Case Rep. 2013; 4(11):1032-4.
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      3. Leake PA, Stakhovskaya O, Hetherington A, Rebscher SJ, Bonham B. Effects of brain-derived neurotrophic factor (BDNF) and electrical stimulation on survival and function of cochlear spiral ganglion neurons in deafened, developing cats. J Assoc Res Otolaryngol. 2013 Apr; 14(2):187-211.
        View in: PubMed
      4. Leake PA, Qureshi A, Plummer J, Okrainec A. Minimally invasive surgery training in the Caribbean--a survey of general surgical residents and their trainers. West Indian Med J. 2012 Oct; 61(7):708-15.
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      5. Schoenecker MC, Bonham BH, Stakhovskaya OA, Snyder RL, Leake PA. Monopolar intracochlear pulse trains selectively activate the inferior colliculus. J Assoc Res Otolaryngol. 2012 Oct; 13(5):655-72.
        View in: PubMed
      6. Leake PA, Hamilton-Johnson TN, Harry M, Gordon-Strachan GM, Plummer JM, Newnham MS. Open abdominal aortic aneurysm repair in the era of endovascular repair. West Indian Med J. 2011 Dec; 60(6):636-40.
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      7. Leake PA, Hradek GT, Hetherington AM, Stakhovskaya O. Brain-derived neurotrophic factor promotes cochlear spiral ganglion cell survival and function in deafened, developing cats. J Comp Neurol. 2011 Jun 1; 519(8):1526-45.
        View in: PubMed
      8. Plummer JM, Mitchell DI, Arthurs M, Leake PA, Deans-Minott J, Cawich SO, Martin A. Laparoscopic colectomy for colonic neoplasms in a developing country. Int J Surg. 2011; 9(5):382-5.
        View in: PubMed
      9. Verbist BM, Skinner MW, Cohen LT, Leake PA, James C, Boëx C, Holden TA, Finley CC, Roland PS, Roland JT, Haller M, Patrick JF, Jolly CN, Faltys MA, Briaire JJ, Frijns JH. Consensus panel on a cochlear coordinate system applicable in histologic, physiologic, and radiologic studies of the human cochlea. Otol Neurotol. 2010 Jul; 31(5):722-30.
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      10. Plummer JM, Bonadie KO, Williams N, Leake PA, Mitchell DI. Duodenal fibrosarcoma mimicking Franz tumour complicated by post-resection chylous ascites. West Indian Med J. 2010 Jan; 59(1):84-7.
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      11. Leake PA, Hradek GT, Bonham BH, Snyder RL. Topography of auditory nerve projections to the cochlear nucleus in cats after neonatal deafness and electrical stimulation by a cochlear implant. J Assoc Res Otolaryngol. 2008 Sep; 9(3):349-72.
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      12. Leake PA, Stakhovskaya O, Hradek GT, Hetherington AM. Factors influencing neurotrophic effects of electrical stimulation in the deafened developing auditory system. Hear Res. 2008 Aug; 242(1-2):86-99.
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      13. Stakhovskaya O, Hradek GT, Snyder RL, Leake PA. Effects of age at onset of deafness and electrical stimulation on the developing cochlear nucleus in cats. Hear Res. 2008 Sep; 243(1-2):69-77.
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      14. Rebscher SJ, Hetherington A, Bonham B, Wardrop P, Whinney D, Leake PA. Considerations for design of future cochlear implant electrode arrays: electrode array stiffness, size, and depth of insertion. J Rehabil Res Dev. 2008; 45(5):731-47.
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      15. Vollmer M, Beitel RE, Snyder RL, Leake PA. Spatial selectivity to intracochlear electrical stimulation in the inferior colliculus is degraded after long-term deafness in cats. J Neurophysiol. 2007 Nov; 98(5):2588-603.
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      16. Jones TA, Leake PA, Snyder RL, Stakhovskaya O, Bonham B. Spontaneous discharge patterns in cochlear spiral ganglion cells before the onset of hearing in cats. J Neurophysiol. 2007 Oct; 98(4):1898-908.
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      17. Rebscher SJ, Hetherington AM, Snyder RL, Leake PA, Bonham BH. Design and fabrication of multichannel cochlear implants for animal research. J Neurosci Methods. 2007 Oct 15; 166(1):1-12.
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      18. Leake PA, Hradek GT, Vollmer M, Rebscher SJ. Neurotrophic effects of GM1 ganglioside and electrical stimulation on cochlear spiral ganglion neurons in cats deafened as neonates. J Comp Neurol. 2007 Apr 20; 501(6):837-53.
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      19. Stakhovskaya O, Sridhar D, Bonham BH, Leake PA. Frequency map for the human cochlear spiral ganglion: implications for cochlear implants. J Assoc Res Otolaryngol. 2007 Jun; 8(2):220-33.
        View in: PubMed
      20. Duncan ND, Gabay L, Williams E, Dundas SE, Plummer N, Leake PA. Hermaphroditism: cytogenetics, gonadal pathology and gender assignment: a case report. West Indian Med J. 2006 Dec; 55(6):430-3.
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      21. Sridhar D, Stakhovskaya O, Leake PA. A frequency-position function for the human cochlear spiral ganglion. Audiol Neurootol. 2006; 11 Suppl 1:16-20.
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      22. Leake PA, Hradek GT, Chair L, Snyder RL. Neonatal deafness results in degraded topographic specificity of auditory nerve projections to the cochlear nucleus in cats. J Comp Neurol. 2006 Jul 1; 497(1):13-31.
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      23. Wardrop P, Whinney D, Rebscher SJ, Roland JT, Luxford W, Leake PA. A temporal bone study of insertion trauma and intracochlear position of cochlear implant electrodes. I: Comparison of Nucleus banded and Nucleus Contour electrodes. Hear Res. 2005 May; 203(1-2):54-67.
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      24. Wardrop P, Whinney D, Rebscher SJ, Luxford W, Leake P. A temporal bone study of insertion trauma and intracochlear position of cochlear implant electrodes. II: Comparison of Spiral Clarion and HiFocus II electrodes. Hear Res. 2005 May; 203(1-2):68-79.
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      25. Vollmer M, Leake PA, Beitel RE, Rebscher SJ, Snyder RL. Degradation of temporal resolution in the auditory midbrain after prolonged deafness is reversed by electrical stimulation of the cochlea. J Neurophysiol. 2005 Jun; 93(6):3339-55.
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      26. Leake PA, Snyder RL, Hradek GT. Postnatal refinement of auditory nerve projections to the cochlear nucleus in cats. J Comp Neurol. 2002 Jun 17; 448(1):6-27.
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      27. Moore CM, Vollmer M, Leake PA, Snyder RL, Rebscher SJ. The effects of chronic intracochlear electrical stimulation on inferior colliculus spatial representation in adult deafened cats. Hear Res. 2002 Feb; 164(1-2):82-96.
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      28. Osofsky MR, Moore CM, Leake PA. Does exogenous GM1 ganglioside enhance the effects of electrical stimulation in ameliorating degeneration after neonatal deafness? Hear Res. 2001 Sep; 159(1-2):23-35.
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      29. Rebscher SJ, Snyder RL, Leake PA. The effect of electrode configuration and duration of deafness on threshold and selectivity of responses to intracochlear electrical stimulation. J Acoust Soc Am. 2001 May; 109(5 Pt 1):2035-48.
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      30. Leake PA, Snyder RL, Rebscher SJ, Moore CM, Vollmer M. Plasticity in central representations in the inferior colliculus induced by chronic single- vs. two-channel electrical stimulation by a cochlear implant after neonatal deafness. Hear Res. 2000 Sep; 147(1-2):221-41.
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      31. Snyder RL, Vollmer M, Moore CM, Rebscher SJ, Leake PA, Beitel RE. Responses of inferior colliculus neurons to amplitude-modulated intracochlear electrical pulses in deaf cats. J Neurophysiol. 2000 Jul; 84(1):166-83.
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      32. Beitel RE, Snyder RL, Schreiner CE, Raggio MW, Leake PA. Electrical cochlear stimulation in the deaf cat: comparisons between psychophysical and central auditory neuronal thresholds. J Neurophysiol. 2000 Apr; 83(4):2145-62.
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      33. Beitel RE, Vollmer M, Snyder RL, Schreiner CE, Leake PA. Behavioral and neurophysiological thresholds for electrical cochlear stimulation in the deaf cat. Audiol Neurootol. 2000 Jan-Feb; 5(1):31-8.
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      34. Vollmer M, Snyder RL, Leake PA, Beitel RE, Moore CM, Rebscher SJ. Temporal properties of chronic cochlear electrical stimulation determine temporal resolution of neurons in cat inferior colliculus. J Neurophysiol. 1999 Dec; 82(6):2883-902.
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      35. Leake PA, Hradek GT, Snyder RL. Chronic electrical stimulation by a cochlear implant promotes survival of spiral ganglion neurons after neonatal deafness. J Comp Neurol. 1999 Oct 4; 412(4):543-62.
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      36. Sato M, Leake PA, Hradek GT. Postnatal development of the organ of Corti in cats: a light microscopic morphometric study. Hear Res. 1999 Jan; 127(1-2):1-13.
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      37. Leake PA, Kuntz AL, Moore CM, Chambers PL. Cochlear pathology induced by aminoglycoside ototoxicity during postnatal maturation in cats. Hear Res. 1997 Nov; 113(1-2):117-32.
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      38. Snyder RL, Leake PA. Topography of spiral ganglion projections to cochlear nucleus during postnatal development in cats. J Comp Neurol. 1997 Jul 28; 384(2):293-311.
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      39. Snyder RL, Leake PA, Hradek GT. Quantitative analysis of spiral ganglion projections to the cat cochlear nucleus. J Comp Neurol. 1997 Mar 3; 379(1):133-49.
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      40. Snyder R, Leake P, Rebscher S, Beitel R. Temporal resolution of neurons in cat inferior colliculus to intracochlear electrical stimulation: effects of neonatal deafening and chronic stimulation. J Neurophysiol. 1995 Feb; 73(2):449-67.
        View in: PubMed
      41. Leake PA, Snyder RL, Hradek GT, Rebscher SJ. Consequences of chronic extracochlear electrical stimulation in neonatally deafened cats. Hear Res. 1995 Jan; 82(1):65-80.
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      42. Lustig LR, Leake PA, Snyder RL, Rebscher SJ. Changes in the cat cochlear nucleus following neonatal deafening and chronic intracochlear electrical stimulation. Hear Res. 1994 Apr; 74(1-2):29-37.
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      43. Leake PA, Snyder RL, Hradek GT. Spatial organization of inner hair cell synapses and cochlear spiral ganglion neurons. J Comp Neurol. 1993 Jul 8; 333(2):257-70.
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      44. Leake PA, Snyder RL, Hradek GT, Rebscher SJ. Chronic intracochlear electrical stimulation in neonatally deafened cats: effects of intensity and stimulating electrode location. Hear Res. 1992 Dec; 64(1):99-117.
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      45. Leake PA, Snyder RL, Merzenich MM. Topographic organization of the cochlear spiral ganglion demonstrated by restricted lesions of the anteroventral cochlear nucleus. J Comp Neurol. 1992 Jun 22; 320(4):468-78.
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      46. Snyder RL, Rebscher SJ, Leake PA, Kelly K, Cao K. Chronic intracochlear electrical stimulation in the neonatally deafened cat. II. Temporal properties of neurons in the inferior colliculus. Hear Res. 1991 Nov; 56(1-2):246-64.
        View in: PubMed
      47. Leake PA, Hradek GT, Rebscher SJ, Snyder RL. Chronic intracochlear electrical stimulation induces selective survival of spiral ganglion neurons in neonatally deafened cats. Hear Res. 1991 Aug; 54(2):251-71.
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      48. Hultcrantz M, Snyder R, Rebscher S, Leake P. Effects of neonatal deafening and chronic intracochlear electrical stimulation on the cochlear nucleus in cats. Hear Res. 1991 Aug; 54(2):272-80.
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      49. Snyder RL, Rebscher SJ, Cao KL, Leake PA, Kelly K. Chronic intracochlear electrical stimulation in the neonatally deafened cat. I: Expansion of central representation. Hear Res. 1990 Dec; 50(1-2):7-33.
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      50. Zook JM, Leake PA. Connections and frequency representation in the auditory brainstem of the mustache bat, Pteronotus parnellii. J Comp Neurol. 1989 Dec 8; 290(2):243-61.
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      51. Jackler RK, Leake PA, McKerrow WS. Cochlear implant revision: effects of reimplantation on the cochlea. Ann Otol Rhinol Laryngol. 1989 Oct; 98(10):813-20.
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      52. Leake PA, Snyder RL. Topographic organization of the central projections of the spiral ganglion in cats. J Comp Neurol. 1989 Mar 22; 281(4):612-29.
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      53. Snyder RL, Leake PA. Intrinsic connections within and between cochlear nucleus subdivisions in cat. J Comp Neurol. 1988 Dec 8; 278(2):209-25.
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      54. Leake PA, Hradek GT. Cochlear pathology of long term neomycin induced deafness in cats. Hear Res. 1988 Apr; 33(1):11-33.
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      55. Leake PA, Snyder RL. Uptake of horseradish peroxidase from perilymph by cochlear hair cells. Hear Res. 1987; 25(2-3):153-71.
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      56. Wong-Riley MT, Merzenich MM, Leake PA. Changes in endogenous enzymatic reactivity to DAB induced by neuronal inactivity. Brain Res. 1978 Feb 3; 141(1):185-92.
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      57. Merzenich MM, White MW, Leake PA, Schindler RA, Michelson RP. Further progress in the development of multichannel cochlear implants. Trans Sect Otolaryngol Am Acad Ophthalmol Otolaryngol. 1977 Mar-Apr; 84(2):181-2.
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      58. Leake PA. Central projections of the statoacoustic nerve in Caiman crocodilus. Brain Behav Evol. 1974; 10(1-3):170-96.
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