Peter Walter, PhD

Title(s)Professor Emeritus, Biochemistry and Biophysics
SchoolSchool of Medicine
AddressLocation Required, #001
Phone415-476-4636
vCardDownload vCard
    Other Positions
    Title(s)Howard Hughes Investigator


    Collapse Biography 
    Collapse Awards and Honors
    Breakthrough Foundation2018Breakthrough Prize in Life Science
    Vilcek Foundation2015Vilcek Prize in Biomedical Science
    Lasker Foundation2014Lasker Basic Medical Research Award
    UCSF2014Shaw Prize in Life Science and Medicine
    UCSF2012Paul Ehrlich and Ludwig Darmstaedter Prize

    Collapse Overview 
    Collapse Overview
    Our laboratory seeks a molecular understanding of how cells control the quality of their proteins and organelles during homeostasis and stress. We are identifying the machinery and mechanisms that ensure proper protein synthesis, folding, and targeting, as well as the pathways that allow organelles to communicate and regulate their abundance. Additionally, we aim to understand how the rewiring of these processes leads to, or prevents the progression of disease. Our laboratory uses a diverse array of techniques, ranging from biochemical reconstitution to genetics, to fuel our search for fundamental discoveries in cell biology.
    Collapse Websites

    Collapse Research 
    Collapse Research Activities and Funding
    Structural Basis of Protein Homeostasis
    NIH U01GM098254Sep 30, 2012 - Jul 31, 2016
    Role: Principal Investigator
    The integrated stress response in cognitive disorders
    NIH R01NS076708Mar 15, 2012 - Mar 31, 2026
    Role: Co-Principal Investigator
    Stress Proteins in Growth, Development &Disease 2007Gordon Research Conference
    NIH R13AG030760Jun 1, 2007 - May 31, 2008
    Role: Principal Investigator
    Membrane Protein Expression Center
    NIH P50GM073210Sep 24, 2004 - Aug 31, 2015
    Role: Co-Investigator
    QUATTRO ALLIANCE FOR SCIENCE AND LANGUAGE INTEGRATION
    NIH R25RR018504Sep 30, 2003 - Aug 31, 2007
    Role: Co-Principal Investigator
    Molecular Cell Biology Gordon Conference
    NIH R13CA091820Jul 1, 2001 - Jun 30, 2002
    Role: Principal Investigator
    Comprehensive Biology: Exploiting the Yeast Genome
    NIH P41RR011823Sep 30, 1996 - Jun 30, 2016
    Role: Co-Investigator
    PROTEIN TRANSLOCATION IN YEAST
    NIH R01GM037485Dec 1, 1986 - Nov 30, 1999
    Role: Principal Investigator
    Co-translational ER quality control
    NIH R01GM032384Jul 1, 1983 - Apr 30, 2024
    Role: Principal Investigator
    MECHANISM OF PROTEIN TRANSLOCATION ACROSS MEMBRANES
    NIH R37GM032384Jul 1, 1983 - Jun 30, 2003
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Featured Content 
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling. Nat Chem Biol. 2024 Apr; 20(4):422-431. Lawrence RE, Shoemaker SR, Deal A, Sangwan S, Anand AA, Wang L, Marqusee S, Walter P. PMID: 37945896; PMCID: PMC10972756.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    2. A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response. Nat Cell Biol. 2023 Nov; 25(11):1600-1615. Subramanian A, Wang L, Moss T, Voorhies M, Sangwan S, Stevenson E, Pulido EH, Kwok S, Chalkley RJ, Li KH, Krogan NJ, Swaney DL, Burlingame AL, Floor SN, Sil A, Walter P, Mukherjee S. PMID: 37857833.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    3. Early Alterations of RNA Binding Protein (RBP) Homeostasis and ER Stress-Mediated Autophagy Contributes to Progressive Retinal Degeneration in the rd10 Mouse Model of Retinitis Pigmentosa (RP). Cells. 2023 04 06; 12(7). Yamoah A, Tripathi P, Guo H, Scheve L, Walter P, Johnen S, Müller F, Weis J, Goswami A. PMID: 37048167; PMCID: PMC10092976.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    4. A central helical switch controls integrated stress response signaling via eIF2B conformation and assembly. Biophysical Journal. 2023 Feb 1; 122(3):32a. Lawrence LR, Shoemaker SS, Deal DA, Wang WL, Marqusee MS, Walter WP. .
      View in: Publisher Site   Mentions:
    5. Observation of site-selective chemical bond changes via ultrafast chemical shifts. Nat Commun. 2022 Nov 22; 13(1):7170. Al-Haddad A, Oberli S, González-Vázquez J, Bucher M, Doumy G, Ho P, Krzywinski J, Lane TJ, Lutman A, Marinelli A, Maxwell TJ, Moeller S, Pratt ST, Ray D, Shepard R, Southworth SH, Vázquez-Mayagoitia Á, Walter P, Young L, Picón A, Bostedt C. PMID: 36418902; PMCID: PMC9684563.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    6. Aberrant cortical spine dynamics after concussive injury are reversed by integrated stress response inhibition. Proc Natl Acad Sci U S A. 2022 10 18; 119(42):e2209427119. Frias ES, Hoseini MS, Krukowski K, Paladini MS, Grue K, Ureta G, Rienecker KDA, Walter P, Stryker MP, Rosi S. PMID: 36227915; PMCID: PMC9586300.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    7. Endoplasmic reticulum stress activates human IRE1α through reversible assembly of inactive dimers into small oligomers. Elife. 2022 06 22; 11. Belyy V, Zuazo-Gaztelu I, Alamban A, Ashkenazi A, Walter P. PMID: 35730415; PMCID: PMC9217129.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    8. Conserved structural elements specialize ATAD1 as a membrane protein extraction machine. Elife. 2022 05 12; 11. Wang L, Toutkoushian H, Belyy V, Kokontis CY, Walter P. PMID: 35550246; PMCID: PMC9273213.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    9. Systematic characterization of gene function in the photosynthetic alga Chlamydomonas reinhardtii. Nat Genet. 2022 05; 54(5):705-714. Fauser F, Vilarrasa-Blasi J, Onishi M, Ramundo S, Patena W, Millican M, Osaki J, Philp C, Nemeth M, Salomé PA, Li X, Wakao S, Kim RG, Kaye Y, Grossman AR, Niyogi KK, Merchant SS, Cutler SR, Walter P, Dinneny JR, Jonikas MC, Jinkerson RE. PMID: 35513725; PMCID: PMC9110296.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    10. A point mutation in the nucleotide exchange factor eIF2B constitutively activates the integrated stress response by allosteric modulation. Elife. 2022 04 13; 11. Boone M, Wang L, Lawrence RE, Frost A, Walter P, Schoof M. PMID: 35416150; PMCID: PMC9132573.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    11. Intercepting IRE1 kinase-FMRP signaling prevents atherosclerosis progression. EMBO Mol Med. 2022 04 07; 14(4):e15344. Yildirim Z, Baboo S, Hamid SM, Dogan AE, Tufanli O, Robichaud S, Emerton C, Diedrich JK, Vatandaslar H, Nikolos F, Gu Y, Iwawaki T, Tarling E, Ouimet M, Nelson DL, Yates JR, Walter P, Erbay E. PMID: 35191199; PMCID: PMC8988208.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    12. Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α. Nat Commun. 2021 12 15; 12(1):7310. Le Thomas A, Ferri E, Marsters S, Harnoss JM, Lawrence DA, Zuazo-Gaztelu I, Modrusan Z, Chan S, Solon M, Chalouni C, Li W, Koeppen H, Rudolph J, Wang W, Wu TD, Walter P, Ashkenazi A. PMID: 34911951; PMCID: PMC8674358.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    13. Viral evasion of the integrated stress response through antagonism of eIF2-P binding to eIF2B. Nat Commun. 2021 12 07; 12(1):7103. Schoof M, Wang L, Cogan JZ, Lawrence RE, Boone M, Wuerth JD, Frost A, Walter P. PMID: 34876554; PMCID: PMC8651678.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    14. BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response. EMBO J. 2021 Nov 02; 40(21):e109149. Castillo K, Rojas-Rivera D, Lisbona F, Caballero B, Nassif M, Court FA, Schuck S, Ibar C, Walter P, Sierralta J, Glavic A, Hetz C. PMID: 34726286; PMCID: PMC8561629.
      View in: PubMed   Mentions:    Fields:    
    15. Small molecule cognitive enhancer reverses age-related memory decline in mice. Brain Behavior and Immunity. 2021 Nov 1; 98:27. Krukowski KK, Nolan NA, Frias FE, Boone BM, Ureta UG, Grue GK, Paladini PM, Elizarraras EE, Delgado DL, Bernales BS, Walter WP, Rosi RS. .
      View in: Publisher Site   Mentions:
    16. The stress-sensing domain of activated IRE1α forms helical filaments in narrow ER membrane tubes. Science. 2021 Oct; 374(6563):52-57. Tran NH, Carter SD, De Mazière A, Ashkenazi A, Klumperman J, Walter P, Jensen GJ. PMID: 34591618; PMCID: PMC9041316.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    17. Cristae-dependent quality control of the mitochondrial genome. Sci Adv. 2021 Sep 03; 7(36):eabi8886. Jakubke C, Roussou R, Maiser A, Schug C, Thoma F, Bunk D, Hörl D, Leonhardt H, Walter P, Klecker T, Osman C. PMID: 34516914; PMCID: PMC8442932.
      View in: PubMed   Mentions: 9     Fields:    
    18. Moderate levels of 5-fluorocytosine cause the emergence of high frequency resistance in cryptococci. Nat Commun. 2021 06 08; 12(1):3418. Chang YC, Lamichhane AK, Cai H, Walter PJ, Bennett JE, Kwon-Chung KJ. PMID: 34103502; PMCID: PMC8187385.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    19. eIF2B Conformation and Assembly State Regulate the Integrated Stress Response. The FASEB Journal. 2021 May 14; 35(S1). Schoof SM, Boone BM, Wang WL, Lawrence LR, Frost FA, Walter WP. .
      View in: Publisher Site   Mentions:
    20. Protomer alignment modulates specificity of RNA substrate recognition by Ire1. Elife. 2021 04 27; 10. Li W, Crotty K, Garrido Ruiz D, Voorhies M, Rivera C, Sil A, Mullins RD, Jacobson MP, Peschek J, Walter P. PMID: 33904404; PMCID: PMC8104961.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    21. Correction: Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response. J Cell Biol. 2021 04 05; 220(4). Schuck S, Prinz WA, Thorn KS, Voss C, Walter P. PMID: 33600553; PMCID: PMC7888336.
      View in: PubMed   Mentions: 3     Fields:    
    22. eIF2B conformation and assembly state regulate the integrated stress response. Elife. 2021 03 10; 10. Schoof M, Boone M, Wang L, Lawrence R, Frost A, Walter P. PMID: 33688831; PMCID: PMC7990499.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    23. Coexpressed subunits of dual genetic origin define a conserved supercomplex mediating essential protein import into chloroplasts. Proc Natl Acad Sci U S A. 2020 12 22; 117(51):32739-32749. Ramundo S, Asakura Y, Salomé PA, Strenkert D, Boone M, Mackinder LCM, Takafuji K, Dinc E, Rahire M, Crèvecoeur M, Magneschi L, Schaad O, Hippler M, Jonikas MC, Merchant S, Nakai M, Rochaix JD, Walter P. PMID: 33273113; PMCID: PMC7768757.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    24. Small molecule cognitive enhancer reverses age-related memory decline in mice. Elife. 2020 12 01; 9. Krukowski K, Nolan A, Frias ES, Boone M, Ureta G, Grue K, Paladini MS, Elizarraras E, Delgado L, Bernales S, Walter P, Rosi S. PMID: 33258451; PMCID: PMC7721440.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    25. An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike. Science. 2020 12 18; 370(6523):1473-1479. Schoof M, Faust B, Saunders RA, Sangwan S, Rezelj V, Hoppe N, Boone M, Billesbølle CB, Puchades C, Azumaya CM, Kratochvil HT, Zimanyi M, Deshpande I, Liang J, Dickinson S, Nguyen HC, Chio CM, Merz GE, Thompson MC, Diwanji D, Schaefer K, Anand AA, Dobzinski N, Zha BS, Simoneau CR, Leon K, White KM, Chio US, Gupta M, Jin M, Li F, Liu Y, Zhang K, Bulkley D, Sun M, Smith AM, Rizo AN, Moss F, Brilot AF, Pourmal S, Trenker R, Pospiech T, Gupta S, Barsi-Rhyne B, Belyy V, Barile-Hill AW, Nock S, Liu Y, Krogan NJ, Ralston CY, Swaney DL, García-Sastre A, Ott M, Vignuzzi M, QCRG Structural Biology Consortium, Walter P, Manglik A. PMID: 33154106; PMCID: PMC7857409.
      View in: PubMed   Mentions: 209     Fields:    Translation:HumansAnimalsCells
    26. Blockade of Retinal Oscillations by Benzodiazepines Improves Efficiency of Electrical Stimulation in the Mouse Model of RP, rd10. Invest Ophthalmol Vis Sci. 2020 11 02; 61(13):37. Gehlen J, Esser S, Schaffrath K, Johnen S, Walter P, Müller F. PMID: 33252632; PMCID: PMC7705397.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    27. Msp1/ATAD1 in Protein Quality Control and Regulation of Synaptic Activities. Annu Rev Cell Dev Biol. 2020 10 06; 36:141-164. Wang L, Walter P. PMID: 32886535.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    28. An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation. bioRxiv. 2020 Aug 17. Schoof M, Faust B, Saunders RA, Sangwan S, Rezelj V, Hoppe N, Boone M, Billesbølle CB, Puchades C, Azumaya CM, Kratochvil HT, Zimanyi M, Deshpande I, Liang J, Dickinson S, Nguyen HC, Chio CM, Merz GE, Thompson MC, Diwanji D, Schaefer K, Anand AA, Dobzinski N, Zha BS, Simoneau CR, Leon K, White KM, Chio US, Gupta M, Jin M, Li F, Liu Y, Zhang K, Bulkley D, Sun M, Smith AM, Rizo AN, Moss F, Brilot AF, Pourmal S, Trenker R, Pospiech T, Gupta S, Barsi-Rhyne B, Belyy V, Barile-Hill AW, Nock S, Liu Y, Krogan NJ, Ralston CY, Swaney DL, García-Sastre A, Ott M, Vignuzzi M, QCRG Structural Biology Consortium, Walter P, Manglik A. PMID: 32817938; PMCID: PMC7430568.
      View in: PubMed   Mentions: 5  
    29. Inhibition of the integrated stress response by viral proteins that block p-eIF2-eIF2B association. Nat Microbiol. 2020 11; 5(11):1361-1373. Rabouw HH, Visser LJ, Passchier TC, Langereis MA, Liu F, Giansanti P, van Vliet ALW, Dekker JG, van der Grein SG, Saucedo JG, Anand AA, Trellet ME, Bonvin AMJJ, Walter P, Heck AJR, de Groot RJ, van Kuppeveld FJM. PMID: 32690955.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    30. Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response. Nat Commun. 2020 05 14; 11(1):2401. Dufey E, Bravo-San Pedro JM, Eggers C, González-Quiroz M, Urra H, Sagredo AI, Sepulveda D, Pihán P, Carreras-Sureda A, Hazari Y, Sagredo EA, Gutierrez D, Valls C, Papaioannou A, Acosta-Alvear D, Campos G, Domingos PM, Pedeux R, Chevet E, Alvarez A, Godoy P, Walter P, Glavic A, Kroemer G, Hetz C. PMID: 32409639; PMCID: PMC7224204.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    31. The integrated stress response: From mechanism to disease. Science. 2020 04 24; 368(6489). Costa-Mattioli M, Walter P. PMID: 32327570; PMCID: PMC8997189.
      View in: PubMed   Mentions: 385     Fields:    Translation:HumansAnimalsCells
    32. IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment. Cancer Res. 2020 06 01; 80(11):2368-2379. Harnoss JM, Le Thomas A, Reichelt M, Guttman O, Wu TD, Marsters SA, Shemorry A, Lawrence DA, Kan D, Segal E, Merchant M, Totpal K, Crocker LM, Mesh K, Dohse M, Solon M, Modrusan Z, Rudolph J, Koeppen H, Walter P, Ashkenazi A. PMID: 32265225; PMCID: PMC7272310.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    33. Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells. Sci Adv. 2020 04; 6(14):eaay9572. Carter SD, Hampton CM, Langlois R, Melero R, Farino ZJ, Calderon MJ, Li W, Wallace CT, Tran NH, Grassucci RA, Siegmund SE, Pemberton J, Morgenstern TJ, Eisenman L, Aguilar JI, Greenberg NL, Levy ES, Yi E, Mitchell WG, Rice WJ, Wigge C, Pilli J, George EW, Aslanoglou D, Courel M, Freyberg RJ, Javitch JA, Wills ZP, Area-Gomez E, Shiva S, Bartolini F, Volchuk A, Murray SA, Aridor M, Fish KN, Walter P, Balla T, Fass D, Wolf SG, Watkins SC, Carazo JM, Jensen GJ, Frank J, Freyberg Z. PMID: 32270040; PMCID: PMC7112762.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    34. Regulating ER protein homeostasis by differentially processing mRNAs. The FASEB Journal. 2020 Apr 1; 34(S1):1-1. Li LW, Crotty CK, Ruiz RD, Peschek PJ, Walter WP. .
      View in: Publisher Site   Mentions:
    35. Integrated Stress Response Inhibitor Reverses Sex-Dependent Behavioral and Cell-Specific Deficits after Mild Repetitive Head Trauma. J Neurotrauma. 2020 06 01; 37(11):1370-1380. Krukowski K, Nolan A, Frias ES, Grue K, Becker M, Ureta G, Delgado L, Bernales S, Sohal VS, Walter P, Rosi S. PMID: 31884883; PMCID: PMC7249463.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    36. Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction. Elife. 2020 01 30; 9. Wang L, Myasnikov A, Pan X, Walter P. PMID: 31999255; PMCID: PMC7018516.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    37. The role of transient resonances for ultra-fast imaging of single sucrose nanoclusters. Nat Commun. 2020 01 09; 11(1):167. Ho PJ, Daurer BJ, Hantke MF, Bielecki J, Al Haddad A, Bucher M, Doumy G, Ferguson KR, Flückiger L, Gorkhover T, Iwan B, Knight C, Moeller S, Osipov T, Ray D, Southworth SH, Svenda M, Timneanu N, Ulmer A, Walter P, Hajdu J, Young L, Maia FRNC, Bostedt C. PMID: 31919346; PMCID: PMC6952381.
      View in: PubMed   Mentions: 8     Fields:    
    38. Misfolded proteins bind and activate death receptor 5 to trigger apoptosis during unresolved endoplasmic reticulum stress. Elife. 2020 01 06; 9. Lam M, Marsters SA, Ashkenazi A, Walter P. PMID: 31904339; PMCID: PMC7041945.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    39. Quantitative microscopy reveals dynamics and fate of clustered IRE1α. Proc Natl Acad Sci U S A. 2020 01 21; 117(3):1533-1542. Belyy V, Tran NH, Walter P. PMID: 31871156; PMCID: PMC6983381.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    40. Activation of the ISR mediates the behavioral and neurophysiological abnormalities in Down syndrome. Science. 2019 11 15; 366(6467):843-849. Zhu PJ, Khatiwada S, Cui Y, Reineke LC, Dooling SW, Kim JJ, Li W, Walter P, Costa-Mattioli M. PMID: 31727829; PMCID: PMC7299149.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    41. Structural insights into ISRIB, a memory-enhancing inhibitor of the integrated stress response. FEBS J. 2020 01; 287(2):239-245. Anand AA, Walter P. PMID: 31550413.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    42. The Mars1 kinase confers photoprotection through signaling in the chloroplast unfolded protein response. Elife. 2019 10 15; 8. Perlaza K, Toutkoushian H, Boone M, Lam M, Iwai M, Jonikas MC, Walter P, Ramundo S. PMID: 31612858; PMCID: PMC6794094.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    43. Mrx6 regulates mitochondrial DNA copy number in Saccharomyces cerevisiae by engaging the evolutionarily conserved Lon protease Pim1. Mol Biol Cell. 2020 03 19; 31(7):527-545. Göke A, Schrott S, Mizrak A, Belyy V, Osman C, Walter P. PMID: 31532710; PMCID: PMC7202074.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    44. From symbiont to parasite: the evolution of for-profit science publishing. Mol Biol Cell. 2019 09 15; 30(20):2537-2542. Walter P, Mullins D. PMID: 31539315; PMCID: PMC6740196.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    45. The Unfolded Protein Response: Detecting and Responding to Fluctuations in the Protein-Folding Capacity of the Endoplasmic Reticulum. Cold Spring Harb Perspect Biol. 2019 09 03; 11(9). Karagöz GE, Acosta-Alvear D, Walter P. PMID: 30670466; PMCID: PMC6719602.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansAnimalsCells
    46. A Novel Role of Fungal Type I Myosin in Regulating Membrane Properties and Its Association with d-Amino Acid Utilization in Cryptococcus gattii. mBio. 2019 08 27; 10(4). Khanal Lamichhane A, Garraffo HM, Cai H, Walter PJ, Kwon-Chung KJ, Chang YC. PMID: 31455652; PMCID: PMC6712397.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    47. Withdrawal: Lipase maturation factor LMF1, membrane topology and interaction with lipase proteins in the endoplasmic reticulum. J Biol Chem. 2019 Aug 09; 294(32):12263. Doolittle MH, Neher SB, Ben-Zeev O, Ling-Liao J, Gallagher CM, Hosseini M, Yin F, Wong H, Walter P, Péterfy M. PMID: 31399538; PMCID: PMC6690689.
      View in: PubMed   Mentions:    Fields:    
    48. Disruption of IRE1α through its kinase domain attenuates multiple myeloma. Proc Natl Acad Sci U S A. 2019 08 13; 116(33):16420-16429. Harnoss JM, Le Thomas A, Shemorry A, Marsters SA, Lawrence DA, Lu M, Chen YA, Qing J, Totpal K, Kan D, Segal E, Merchant M, Reichelt M, Ackerly Wallweber H, Wang W, Clark K, Kaufman S, Beresini MH, Laing ST, Sandoval W, Lorenzo M, Wu J, Ly J, De Bruyn T, Heidersbach A, Haley B, Gogineni A, Weimer RM, Lee D, Braun MG, Rudolph J, VanWyngarden MJ, Sherbenou DW, Gomez-Bougie P, Amiot M, Acosta-Alvear D, Walter P, Ashkenazi A. PMID: 31371506; PMCID: PMC6697881.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    49. In vitro RNA Cleavage Assays to Characterize IRE1-dependent RNA Decay. Bio Protoc. 2019 Jul 20; 9(14):e3307. Karagöz GE, Peschek J, Walter P, Acosta-Alvear D. PMID: 33654817; PMCID: PMC7854161.
      View in: PubMed   Mentions: 1  
    50. tRNA ligase structure reveals kinetic competition between non-conventional mRNA splicing and mRNA decay. Elife. 2019 06 25; 8. Peschek J, Walter P. PMID: 31237564; PMCID: PMC6592678.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    51. Pulmonary Iron Limitation Induced by Exogenous Type I IFN Protects Mice from Cryptococcus gattii Independently of T Cells. mBio. 2019 06 18; 10(3). Davis MJ, Moyer S, Hoke ES, Sionov E, Mayer-Barber KD, Barber DL, Cai H, Jenkins L, Walter PJ, Chang YC, Kwon-Chung KJ. PMID: 31213551; PMCID: PMC6581853.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    52. Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether. Elife. 2019 05 31; 8. Torres SE, Gallagher CM, Plate L, Gupta M, Liem CR, Guo X, Tian R, Stroud RM, Kampmann M, Weissman JS, Walter P. PMID: 31149896; PMCID: PMC6588346.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    53. eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response. Science. 2019 05 03; 364(6439):491-495. Kenner LR, Anand AA, Nguyen HC, Myasnikov AG, Klose CJ, McGeever LA, Tsai JC, Miller-Vedam LE, Walter P, Frost A. PMID: 31048491; PMCID: PMC6601628.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    54. Electrospray sample injection for single-particle imaging with x-ray lasers. Sci Adv. 2019 05; 5(5):eaav8801. Bielecki J, Hantke MF, Daurer BJ, Reddy HKN, Hasse D, Larsson DSD, Gunn LH, Svenda M, Munke A, Sellberg JA, Flueckiger L, Pietrini A, Nettelblad C, Lundholm I, Carlsson G, Okamoto K, Timneanu N, Westphal D, Kulyk O, Higashiura A, van der Schot G, Loh ND, Wysong TE, Bostedt C, Gorkhover T, Iwan B, Seibert MM, Osipov T, Walter P, Hart P, Bucher M, Ulmer A, Ray D, Carini G, Ferguson KR, Andersson I, Andreasson J, Hajdu J, Maia FRNC. PMID: 31058226; PMCID: PMC6499549.
      View in: PubMed   Mentions: 21     Fields:    
    55. Abstract # 2056 Inhibition of the integrated stress response reverses cognitive deficits after traumatic brain injury. Brain Behavior and Immunity. 2019 Feb 1; 76:e5. Krukowski KK, Chou CA, Jopson JT, Zhu ZP, Costa-Mattioli CM, Walter WP, Rosi RS. .
      View in: Publisher Site   Mentions:
    56. Small molecule ISRIB suppresses the integrated stress response within a defined window of activation. Proc Natl Acad Sci U S A. 2019 02 05; 116(6):2097-2102. Rabouw HH, Langereis MA, Anand AA, Visser LJ, de Groot RJ, Walter P, van Kuppeveld FJM. PMID: 30674674; PMCID: PMC6369741.
      View in: PubMed   Mentions: 94     Fields:    Translation:HumansAnimalsCells
    57. The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1. Elife. 2018 12 24; 7. Acosta-Alvear D, Karagöz GE, Fröhlich F, Li H, Walther TC, Walter P. PMID: 30582518; PMCID: PMC6336407.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    58. Confirming a critical role for death receptor 5 and caspase-8 in apoptosis induction by endoplasmic reticulum stress. Cell Death Differ. 2018 08; 25(8):1530-1531. Lam M, Lawrence DA, Ashkenazi A, Walter P. PMID: 29991746; PMCID: PMC6113221.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    59. Engineering ER-stress dependent non-conventional mRNA splicing. Elife. 2018 07 09; 7. Li W, Okreglak V, Peschek J, Kimmig P, Zubradt M, Weissman JS, Walter P. PMID: 29985129; PMCID: PMC6037481.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    60. Leonardo Gallery: Scientific Delirium Madness 4.0. Leonardo. 2018 Jun 1; 51(03):227-238. Knight KM, Nardelli NM, Davidson DA, Eklund EK, Hawthorne HK, LaCerva LG, LeBoeuf LA, Le Gal LP, Ramirez RA, Spence SH, Tejerina-Risso TJ, Walter WP. .
      View in: Publisher Site   Mentions:
    61. Development of a stress response therapy targeting aggressive prostate cancer. Sci Transl Med. 2018 05 02; 10(439). Nguyen HG, Conn CS, Kye Y, Xue L, Forester CM, Cowan JE, Hsieh AC, Cunningham JT, Truillet C, Tameire F, Evans MJ, Evans CP, Yang JC, Hann B, Koumenis C, Walter P, Carroll PR, Ruggero D. PMID: 29720449; PMCID: PMC6045425.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    62. Günter Blobel (1936-2018). Science. 2018 Apr 27; 360(6387):383. Walter P, Anderson D. PMID: 29700255.
      View in: PubMed   Mentions:    Fields:    
    63. Retraction Notice to: The Unfolded Protein Response Element IRE1α Senses Bacterial Proteins Invading the ER to Activate RIG-I and Innate Immune Signaling. Cell Host Microbe. 2018 04 11; 23(4):571. Cho JA, Lee AH, Platzer B, Cross BCS, Gardner BM, De Luca H, Luong P, Harding HP, Glimcher LH, Walter P, Fiebiger E, Ron D, Kagan JC, Lencer WI. PMID: 29649448; PMCID: PMC5916756.
      View in: PubMed   Mentions: 1     Fields:    
    64. Regulating ER Protein Folding Homeostasis By Distinctively Processing mRNAs. The FASEB Journal. 2018 Apr 1; 32:653.9-653.9. Li LW, Okreglak OV, Peschek PJ, Kimmig KP, Walter WP. .
      View in: Publisher Site   Mentions:
    65. Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule. Science. 2018 03 30; 359(6383). Tsai JC, Miller-Vedam LE, Anand AA, Jaishankar P, Nguyen HC, Renslo AR, Frost A, Walter P. PMID: 29599213; PMCID: PMC6120582.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    66. An unfolded protein-induced conformational switch activates mammalian IRE1. Elife. 2017 10 03; 6. Karagöz GE, Acosta-Alvear D, Nguyen HT, Lee CP, Chu F, Walter P. PMID: 28971800; PMCID: PMC5699868.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansCells
    67. Regulated Ire1-dependent mRNA decay requires no-go mRNA degradation to maintain endoplasmic reticulum homeostasis in S. pombe. Elife. 2017 09 25; 6. Guydosh NR, Kimmig P, Walter P, Green R. PMID: 28945192; PMCID: PMC5650469.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    68. Iron affects Ire1 clustering propensity and the amplitude of endoplasmic reticulum stress signaling. J Cell Sci. 2017 Oct 01; 130(19):3222-3233. Cohen N, Breker M, Bakunts A, Pesek K, Chas A, Argemí J, Orsi A, Gal L, Chuartzman S, Wigelman Y, Jonas F, Walter P, Ernst R, Aragón T, van Anken E, Schuldiner M. PMID: 28794014; PMCID: PMC5665437.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    69. Inhibition of the integrated stress response reverses cognitive deficits after traumatic brain injury. Proc Natl Acad Sci U S A. 2017 08 01; 114(31):E6420-E6426. Chou A, Krukowski K, Jopson T, Zhu PJ, Costa-Mattioli M, Walter P, Rosi S. PMID: 28696288; PMCID: PMC5547647.
      View in: PubMed   Mentions: 97     Fields:    Translation:AnimalsCells
    70. BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response. EMBO J. 2017 06 01; 36(11):1640. Castillo K, Rojas-Rivera D, Lisbona F, Caballero B, Nassif M, Court FA, Schuck S, Ibar C, Walter P, Sierralta J, Glavic A, Hetz C. PMID: 28572284; PMCID: PMC5452024.
      View in: PubMed   Mentions: 1     Fields:    
    71. Targeting IRE1 with small molecules counteracts progression of atherosclerosis. Proc Natl Acad Sci U S A. 2017 02 21; 114(8):E1395-E1404. Tufanli O, Telkoparan Akillilar P, Acosta-Alvear D, Kocaturk B, Onat UI, Hamid SM, Çimen I, Walter P, Weber C, Erbay E. PMID: 28137856; PMCID: PMC5338400.
      View in: PubMed   Mentions: 92     Fields:    Translation:AnimalsCells
    72. eIF2α-mediated translational control regulates the persistence of cocaine-induced LTP in midbrain dopamine neurons. Elife. 2016 12 13; 5. Placzek AN, Prisco GV, Khatiwada S, Sgritta M, Huang W, Krnjevic K, Kaufman RJ, Dani JA, Walter P, Costa-Mattioli M. PMID: 27960077; PMCID: PMC5154759.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    73. Multiple selection filters ensure accurate tail-anchored membrane protein targeting. Elife. 2016 12 07; 5. Rao M, Okreglak V, Chio US, Cho H, Walter P, Shan SO. PMID: 27925580; PMCID: PMC5214336.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    74. CD46 Is Amplified in High-Risk Myeloma with Gain of Chromosome 1q and Selectively Targeted By a Novel Anti-CD46 Antibody-Drug Conjugate. Blood. 2016 Dec 2; 128(22):384-384. Sherbenou SD, Aftab AB, Su SY, Behrens BC, Wiita WA, Logan LA, Acosta-Alvear AD, Hann HB, Walter WP, Wu WX, Atkinson AJ, Wolf WJ, Martin MT, Liu LB. .
      View in: Publisher Site   Mentions:
    75. Antibody-drug conjugate targeting CD46 eliminates multiple myeloma cells. J Clin Invest. 2016 12 01; 126(12):4640-4653. Sherbenou DW, Aftab BT, Su Y, Behrens CR, Wiita A, Logan AC, Acosta-Alvear D, Hann BC, Walter P, Shuman MA, Wu X, Atkinson JP, Wolf JL, Martin TG, Liu B. PMID: 27841764; PMCID: PMC5127683.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    76. Science as a Way of Knowing: From Protein Machines to Evidence-Based Decisions. Cell. 2016 Sep 22; 167(1):16-19. Walter P, Yamamoto KR. PMID: 27634318.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    77. Combined chemical-genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma. Proc Natl Acad Sci U S A. 2016 08 09; 113(32):9015-20. Sabnis AJ, Guerriero CJ, Olivas V, Sayana A, Shue J, Flanagan J, Asthana S, Paton AW, Paton JC, Gestwicki JE, Walter P, Weissman JS, Wipf P, Brodsky JL, Bivona TG. PMID: 27450084; PMCID: PMC4987817.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    78. Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation. Elife. 2016 07 20; 5. Plate L, Cooley CB, Chen JJ, Paxman RJ, Gallagher CM, Madoux F, Genereux JC, Dobbs W, Garza D, Spicer TP, Scampavia L, Brown SJ, Rosen H, Powers ET, Walter P, Hodder P, Wiseman RL, Kelly JW. PMID: 27435961; PMCID: PMC4954754.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansCells
    79. Ceapins inhibit ATF6α signaling by selectively preventing transport of ATF6α to the Golgi apparatus during ER stress. Elife. 2016 07 20; 5. Gallagher CM, Walter P. PMID: 27435962; PMCID: PMC4954756.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    80. Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch. Elife. 2016 07 20; 5. Gallagher CM, Garri C, Cain EL, Ang KK, Wilson CG, Chen S, Hearn BR, Jaishankar P, Aranda-Diaz A, Arkin MR, Renslo AR, Walter P. PMID: 27435960; PMCID: PMC4954757.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansCells
    81. Evaluation of Retinal Function and Morphology of the Pink-Eyed Royal College of Surgeons (RCS) Rat: A Comparative Study of in Vivo and in Vitro Methods. Curr Eye Res. 2017 02; 42(2):273-281. Rösch S, Aretzweiler C, Müller F, Walter P. PMID: 27362633.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    82. Translational control of nicotine-evoked synaptic potentiation in mice and neuronal responses in human smokers by eIF2α. Elife. 2016 Mar 01; 5. Placzek AN, Molfese DL, Khatiwada S, Viana Di Prisco G, Huang W, Sidrauski C, Krnjevic K, Amos CL, Ray R, Dani JA, Walter P, Salas R, Costa-Mattioli M. PMID: 26928076; PMCID: PMC4786418.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    83. Translational control by eIF2α phosphorylation regulates vulnerability to the synaptic and behavioral effects of cocaine. Elife. 2016 Mar 01; 5. Huang W, Placzek AN, Viana Di Prisco G, Khatiwada S, Sidrauski C, Krnjevic K, Walter P, Dani JA, Costa-Mattioli M. PMID: 26928234; PMCID: PMC4786430.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    84. Translation from the 5' untranslated region shapes the integrated stress response. Science. 2016 Jan 29; 351(6272):aad3867. Starck SR, Tsai JC, Chen K, Shodiya M, Wang L, Yahiro K, Martins-Green M, Shastri N, Walter P. PMID: 26823435; PMCID: PMC4882168.
      View in: PubMed   Mentions: 187     Fields:    Translation:HumansCells
    85. Structure-Activity Studies of Bis-O-Arylglycolamides: Inhibitors of the Integrated Stress Response. ChemMedChem. 2016 Apr 19; 11(8):870-80. Hearn BR, Jaishankar P, Sidrauski C, Tsai JC, Vedantham P, Fontaine SD, Walter P, Renslo AR. PMID: 26789650.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    86. Dynamics of co-translational protein targeting. Curr Opin Chem Biol. 2015 Dec; 29:79-86. Elvekrog MM, Walter P. PMID: 26517565; PMCID: PMC4684440.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    87. A conformational RNA zipper promotes intron ejection during non-conventional XBP1 mRNA splicing. EMBO Rep. 2015 Dec; 16(12):1688-98. Peschek J, Acosta-Alvear D, Mendez AS, Walter P. PMID: 26483401; PMCID: PMC4687415.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    88. ER-mitochondrial junctions can be bypassed by dominant mutations in the endosomal protein Vps13. J Cell Biol. 2015 Sep 14; 210(6):883-90. Lang AB, John Peter AT, Walter P, Kornmann B. PMID: 26370498; PMCID: PMC4576869.
      View in: PubMed   Mentions: 123     Fields:    Translation:AnimalsCells
    89. Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits. Elife. 2015 Sep 01; 4:e08153. Acosta-Alvear D, Cho MY, Wild T, Buchholz TJ, Lerner AG, Simakova O, Hahn J, Korde N, Landgren O, Maric I, Choudhary C, Walter P, Weissman JS, Kampmann M. PMID: 26327694; PMCID: PMC4602331.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    90. Abstract A43: Opposing roles of the 19S regulatory- and 20S core-proteasomal subunits in controlling sensitivity of multiple myeloma cells to proteasome inhibition. Myeloma. 2015 Sep 1; a43-a43. Acosta-Alvear AD, Kampmann KM, Cho CM, Wild WT, Choudhary CC, Shuman SM, Weissman WJ, Walter WP. .
      View in: Publisher Site   Mentions:
    91. Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic. Elife. 2015 May 19; 4. Mendez AS, Alfaro J, Morales-Soto MA, Dar AC, McCullagh E, Gotthardt K, Li H, Acosta-Alvear D, Sidrauski C, Korennykh AV, Bernales S, Shokat KM, Walter P. PMID: 25986605; PMCID: PMC4436593.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    92. Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response. Elife. 2015 Apr 15; 4:e07314. Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, Renslo AR, Walter P. PMID: 25875391; PMCID: PMC4426669.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansCells
    93. The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly. Elife. 2015 Feb 26; 4. Sidrauski C, McGeachy AM, Ingolia NT, Walter P. PMID: 25719440; PMCID: PMC4341466.
      View in: PubMed   Mentions: 268     Fields:    Translation:AnimalsCells
    94. Integrity of the yeast mitochondrial genome, but not its distribution and inheritance, relies on mitochondrial fission and fusion. Proc Natl Acad Sci U S A. 2015 Mar 03; 112(9):E947-56. Osman C, Noriega TR, Okreglak V, Fung JC, Walter P. PMID: 25730886; PMCID: PMC4352819.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    95. Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer. Mol Cancer Ther. 2015 Mar; 14(3):642-8. Li X, Colvin T, Rauch JN, Acosta-Alvear D, Kampmann M, Dunyak B, Hann B, Aftab BT, Murnane M, Cho M, Walter P, Weissman JS, Sherman MY, Gestwicki JE. PMID: 25564440; PMCID: PMC4456214.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    96. Specificity in endoplasmic reticulum-stress signaling in yeast entails a step-wise engagement of HAC1 mRNA to clusters of the stress sensor Ire1. Elife. 2014 Dec 30; 3:e05031. van Anken E, Pincus D, Coyle S, Aragón T, Osman C, Lari F, Gómez Puerta S, Korennykh AV, Walter P. PMID: 25549299; PMCID: PMC4279078.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    97. Real-time observation of signal recognition particle binding to actively translating ribosomes. Elife. 2014 Oct 30; 3. Noriega TR, Chen J, Walter P, Puglisi JD. PMID: 25358118; PMCID: PMC4213662.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    98. Lasker Award winner Peter Walter. Nat Med. 2014 Oct; 20(10):1112-4. Walter P. PMID: 25295946.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    99. Delayed Ras/PKA signaling augments the unfolded protein response. Proc Natl Acad Sci U S A. 2014 Oct 14; 111(41):14800-5. Pincus D, Aranda-Díaz A, Zuleta IA, Walter P, El-Samad H. PMID: 25275008; PMCID: PMC4205644.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    100. ER-phagy mediates selective degradation of endoplasmic reticulum independently of the core autophagy machinery. J Cell Sci. 2014 Sep 15; 127(Pt 18):4078-88. Schuck S, Gallagher CM, Walter P. PMID: 25052096; PMCID: PMC4163648.
      View in: PubMed   Mentions: 136     Fields:    Translation:AnimalsCells
    101. Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis. Science. 2014 Jul 04; 345(6192):98-101. Lu M, Lawrence DA, Marsters S, Acosta-Alvear D, Kimmig P, Mendez AS, Paton AW, Paton JC, Walter P, Ashkenazi A. PMID: 24994655; PMCID: PMC4284148.
      View in: PubMed   Mentions: 291     Fields:    Translation:HumansAnimalsCells
    102. Translational control of mGluR-dependent long-term depression and object-place learning by eIF2α. Nat Neurosci. 2014 Aug; 17(8):1073-82. Di Prisco GV, Huang W, Buffington SA, Hsu CC, Bonnen PE, Placzek AN, Sidrauski C, Krnjevic K, Kaufman RJ, Walter P, Costa-Mattioli M. PMID: 24974795; PMCID: PMC4340591.
      View in: PubMed   Mentions: 107     Fields:    Translation:AnimalsCells
    103. The conserved AAA-ATPase Msp1 confers organelle specificity to tail-anchored proteins. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):8019-24. Okreglak V, Walter P. PMID: 24821790; PMCID: PMC4050615.
      View in: PubMed   Mentions: 96     Fields:    Translation:AnimalsCells
    104. Signal recognition particle-ribosome binding is sensitive to nascent chain length. J Biol Chem. 2014 Jul 11; 289(28):19294-305. Noriega TR, Tsai A, Elvekrog MM, Petrov A, Neher SB, Chen J, Bradshaw N, Puglisi JD, Walter P. PMID: 24808175; PMCID: PMC4094042.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    105. Molecular mechanisms of hypoxic responses via unique roles of Ras1, Cdc24 and Ptp3 in a human fungal pathogen Cryptococcus neoformans. PLoS Genet. 2014 Apr; 10(4):e1004292. Chang YC, Khanal Lamichhane A, Garraffo HM, Walter PJ, Leerkes M, Kwon-Chung KJ. PMID: 24762475; PMCID: PMC3998916.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    106. Identification of key components involved in mtDNA inheritance during cell division (965.1). The FASEB Journal. 2014 Apr 1; 28. Camacho CB, Osman OC, Walter WP. .
      View in: Publisher Site   Mentions:
    107. Heat shock transcription factor σ32 co-opts the signal recognition particle to regulate protein homeostasis in E. coli. PLoS Biol. 2013 Dec; 11(12):e1001735. Lim B, Miyazaki R, Neher S, Siegele DA, Ito K, Walter P, Akiyama Y, Yura T, Gross CA. PMID: 24358019; PMCID: PMC3866087.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells
    108. Abstract PR07: Systematic genetic interaction maps reveal rewiring of the stress response network and resulting vulnerabilities in leukemia and multiple myeloma cells. Interpreting the Cancer Genome. 2013 Oct 1; pr07-pr07. Kampmann KM, Acosta-Alvear AD, Cho CM, Chen CY, Li LX, Gilbert GL, Aftab AB, Gestwicki GJ, Walter WP, Weissman WJ. .
      View in: Publisher Site   Mentions:
    109. Abstract C01: Systematic blueprinting of genetic vulnerabilities using ultra-complex shRNA libraries identifies genes synergizing with proteasome inhibition or blockade of IRE1 in multiple myeloma cells. Signaling and Drug Resistance. 2013 Oct 1; c01-c01. Acosta-Alvear AD, Kampmann KM, Bassik BM, Lee LC, Cho CM, Aftab AB, Li LX, Gestwicki GJ, Shuman SM, Weissman WJ, Walter WP. .
      View in: Publisher Site   Mentions:
    110. Pharmacological brake-release of mRNA translation enhances cognitive memory. Elife. 2013 May 28; 2:e00498. Sidrauski C, Acosta-Alvear D, Khoutorsky A, Vedantham P, Hearn BR, Li H, Gamache K, Gallagher CM, Ang KK, Wilson C, Okreglak V, Ashkenazi A, Hann B, Nader K, Arkin MR, Renslo AR, Sonenberg N, Walter P. PMID: 23741617; PMCID: PMC3667625.
      View in: PubMed   Mentions: 327     Fields:    Translation:HumansAnimalsCells
    111. The unfolded protein response element IRE1α senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling. Cell Host Microbe. 2013 May 15; 13(5):558-569. Cho JA, Lee AH, Platzer B, Cross BCS, Gardner BM, De Luca H, Luong P, Harding HP, Glimcher LH, Walter P, Fiebiger E, Ron D, Kagan JC, Lencer WI. PMID: 23684307; PMCID: PMC3766372.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    112. ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast. Elife. 2013 May 14; 2:e00422. Murley A, Lackner LL, Osman C, West M, Voeltz GK, Walter P, Nunnari J. PMID: 23682313; PMCID: PMC3654481.
      View in: PubMed   Mentions: 176     Fields:    Translation:AnimalsCells
    113. Abstract A08: Systematic identification of genetic vulnerabilities synergizing with proteasome and IRE1 inhibition in multiple myeloma cells using ultra-complex shRNA libraries. Genome Scale Synthetic Lethal Screens in Model Organisms. 2013 May 1; a08-a08. Acosta-Alvear AD, Kampmann KM, Bassik BM, Lee LC, Shuman SM, Weissman WJ, Walter WP. .
      View in: Publisher Site   Mentions:
    114. Abstract PR06: Systematic genetic interaction maps reveal synthetic-lethal vulnerabilities in leukemia and multiple myeloma. Systemic Functional Genomics. 2013 May 1; pr06-pr06. Kampmann KM, Acosta-Alvear AD, Bassik BM, Chen CY, Walter WP, Weissman WJ. .
      View in: Publisher Site   Mentions:
    115. Two structure papers, a call from Frankfurt airport, and how to escape from reviewer delays: an interview with Peter Walter by Miranda Robertson. BMC Biol. 2013 Apr 15; 11:34. Walter P. PMID: 23587131; PMCID: PMC3626913.
      View in: PubMed   Mentions:    Fields:    
    116. Predicting where small molecules bind at protein-protein interfaces. PLoS One. 2013; 8(3):e58583. Walter P, Metzger J, Thiel C, Helms V. PMID: 23505538; PMCID: PMC3591369.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    117. Endoplasmic reticulum stress sensing in the unfolded protein response. Cold Spring Harb Perspect Biol. 2013 Mar 01; 5(3):a013169. Gardner BM, Pincus D, Gotthardt K, Gallagher CM, Walter P. PMID: 23388626; PMCID: PMC3578356.
      View in: PubMed   Mentions: 359     Fields:    Translation:HumansAnimalsCells
    118. The unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis. Elife. 2012 Oct 15; 1:e00048. Kimmig P, Diaz M, Zheng J, Williams CC, Lang A, Aragón T, Li H, Walter P. PMID: 23066505; PMCID: PMC3470409.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    119. Basic leucine zipper transcription factor Hac1 binds DNA in two distinct modes as revealed by microfluidic analyses. Proc Natl Acad Sci U S A. 2012 Nov 06; 109(45):E3084-93. Fordyce PM, Pincus D, Kimmig P, Nelson CS, El-Samad H, Walter P, DeRisi JL. PMID: 23054834; PMCID: PMC3494901.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    120. A quaternary equation for interdisciplinary medical research (IMR). Journal of Translational Medicine. 2012 Oct 1; 10(Suppl 2):a49. Shuman SM, Wells WJ, Shokat SK, Bernales BS, Walter WP, Shultz SL, Goodwin GN. .
      View in: Publisher Site   Mentions:
    121. A first line of defense against ER stress. J Cell Biol. 2012 Aug 06; 198(3):277-9. Pincus D, Walter P. PMID: 22869593; PMCID: PMC3413362.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    122. Seg1 controls eisosome assembly and shape. J Cell Biol. 2012 Aug 06; 198(3):405-20. Moreira KE, Schuck S, Schrul B, Fröhlich F, Moseley JB, Walther TC, Walter P. PMID: 22869600; PMCID: PMC3413353.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    123. Structural basis of the unfolded protein response. Annu Rev Cell Dev Biol. 2012; 28:251-77. Korennykh A, Walter P. PMID: 23057742.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansAnimalsCells
    124. The unfolded protein response: from stress pathway to homeostatic regulation. Science. 2011 Nov 25; 334(6059):1081-6. Walter P, Ron D. PMID: 22116877.
      View in: PubMed   Mentions: 2713     Fields:    Translation:HumansAnimalsCells
    125. Antimyeloma Effects of the Heat Shock Protein 70 Molecular Chaperone Inhibitor MAL3-101. J Oncol. 2011; 2011:232037. Braunstein MJ, Scott SS, Scott CM, Behrman S, Walter P, Wipf P, Coplan JD, Chrico W, Joseph D, Brodsky JL, Batuman O. PMID: 21977030; PMCID: PMC3184436.
      View in: PubMed   Mentions: 48  
    126. BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response. EMBO J. 2011 Sep 16; 30(21):4465-78. Castillo K, Rojas-Rivera D, Lisbona F, Caballero B, Nassif M, Court FA, Schuck S, Ibar C, Walter P, Sierralta J, Glavic A, Hetz C. PMID: 21926971; PMCID: PMC3230375.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    127. Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response. Science. 2011 Sep 30; 333(6051):1891-4. Gardner BM, Walter P. PMID: 21852455; PMCID: PMC3202989.
      View in: PubMed   Mentions: 334     Fields:    Translation:Cells
    128. The conserved GTPase Gem1 regulates endoplasmic reticulum-mitochondria connections. Proc Natl Acad Sci U S A. 2011 Aug 23; 108(34):14151-6. Kornmann B, Osman C, Walter P. PMID: 21825164; PMCID: PMC3161550.
      View in: PubMed   Mentions: 165     Fields:    Translation:AnimalsCells
    129. Concerted complex assembly and GTPase activation in the chloroplast signal recognition particle. Biochemistry. 2011 Aug 23; 50(33):7208-17. Nguyen TX, Chandrasekar S, Neher S, Walter P, Shan SO. PMID: 21780778; PMCID: PMC6309729.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    130. Endogenic regulation of proliferation and zinc transporters by pigment epithelial cells nonvirally transfected with PEDF. Invest Ophthalmol Vis Sci. 2011 Jul 23; 52(8):5400-7. Johnen S, Kazanskaya O, Armogan N, Stickelmann C, Stöcker M, Walter P, Thumann G. PMID: 21508100.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    131. Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1. BMC Biol. 2011 Jul 06; 9:48. Korennykh AV, Egea PF, Korostelev AA, Finer-Moore J, Stroud RM, Zhang C, Shokat KM, Walter P. PMID: 21729334; PMCID: PMC3158555.
      View in: PubMed   Mentions: 37     Fields:    Translation:Cells
    132. Structural and functional basis for RNA cleavage by Ire1. BMC Biol. 2011 Jul 06; 9:47. Korennykh AV, Korostelev AA, Egea PF, Finer-Moore J, Stroud RM, Zhang C, Shokat KM, Walter P. PMID: 21729333; PMCID: PMC3149027.
      View in: PubMed   Mentions: 46     Fields:    Translation:Cells
    133. Presence of xenogenic mouse RNA in RPE and IPE cells cultured on mitotically inhibited 3T3 fibroblasts. Invest Ophthalmol Vis Sci. 2011 Apr 25; 52(5):2817-24. Johnen S, Wickert L, Meier M, Salz AK, Walter P, Thumann G. PMID: 21220557.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    134. Peter Walter: investigating how the ER handles secretory proteins. Interview by Sedwick Caitlin. J Cell Biol. 2011 Apr 04; 193(1):4-5. Walter P. PMID: 21464225; PMCID: PMC3082191.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    135. Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity. J Cell Biol. 2011 Apr 04; 193(1):171-84. Rubio C, Pincus D, Korennykh A, Schuck S, El-Samad H, Walter P. PMID: 21444684; PMCID: PMC3082176.
      View in: PubMed   Mentions: 86     Fields:    Translation:AnimalsCells
    136. A CHOP-regulated microRNA controls rhodopsin expression. J Cell Biol. 2011 Mar 21; 192(6):919-27. Behrman S, Acosta-Alvear D, Walter P. PMID: 21402790; PMCID: PMC3063143.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    137. Prediction of the exposure status of transmembrane beta barrel residues from protein sequence. J Bioinform Comput Biol. 2011 Feb; 9(1):43-65. Hayat S, Walter P, Park Y, Helms V. PMID: 21328706.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    138. Multi-Modality Imaging of Multiple Myeloma Bone Disease In Orthotopic Xenograft Models. Blood. 2010 Nov 19; 116(21):5014-5014. Acosta-Alvear AD, Hann HB, Rabinovich RB, Shuman SM, Walter WP. .
      View in: Publisher Site   Mentions:
    139. Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering. Proc Natl Acad Sci U S A. 2010 Sep 14; 107(37):16113-8. Li H, Korennykh AV, Behrman SL, Walter P. PMID: 20798350; PMCID: PMC2941319.
      View in: PubMed   Mentions: 188     Fields:    Translation:HumansAnimalsCells
    140. BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response. PLoS Biol. 2010 Jul 06; 8(7):e1000415. Pincus D, Chevalier MW, Aragón T, van Anken E, Vidal SE, El-Samad H, Walter P. PMID: 20625545; PMCID: PMC2897766.
      View in: PubMed   Mentions: 219     Fields:    Translation:AnimalsCells
    141. Automated identification of pathways from quantitative genetic interaction data. Mol Syst Biol. 2010 Jun 08; 6:379. Battle A, Jonikas MC, Walter P, Weissman JS, Koller D. PMID: 20531408; PMCID: PMC2913392.
      View in: PubMed   Mentions: 42     Fields:    Translation:Cells
    142. A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking. Nat Struct Mol Biol. 2010 Jul; 17(7):901-8. Aguilar PS, Fröhlich F, Rehman M, Shales M, Ulitsky I, Olivera-Couto A, Braberg H, Shamir R, Walter P, Mann M, Ejsing CS, Krogan NJ, Walther TC. PMID: 20526336; PMCID: PMC3073498.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    143. The yeast cell fusion protein Prm1p requires covalent dimerization to promote membrane fusion. PLoS One. 2010 May 11; 5(5):e10593. Engel A, Aguilar PS, Walter P. PMID: 20485669; PMCID: PMC2868043.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    144. ERMES-mediated ER-mitochondria contacts: molecular hubs for the regulation of mitochondrial biology. J Cell Sci. 2010 May 01; 123(Pt 9):1389-93. Kornmann B, Walter P. PMID: 20410371; PMCID: PMC2858017.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansAnimalsCells
    145. Structure of sterol aliphatic chains affects yeast cell shape and cell fusion during mating. Proc Natl Acad Sci U S A. 2010 Mar 02; 107(9):4170-5. Aguilar PS, Heiman MG, Walther TC, Engel A, Schwudke D, Gushwa N, Kurzchalia T, Walter P. PMID: 20150508; PMCID: PMC2840153.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    146. Walking along the serendipitous path of discovery. Mol Biol Cell. 2010 Jan 01; 21(1):15-7. Walter P. PMID: 20048259; PMCID: PMC2801708.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    147. Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response. J Cell Biol. 2009 Nov 16; 187(4):525-36. Schuck S, Prinz WA, Thorn KS, Voss C, Walter P. PMID: 19948500; PMCID: PMC2779237.
      View in: PubMed   Mentions: 271     Fields:    Translation:AnimalsCells
    148. Lipase maturation factor LMF1, membrane topology and interaction with lipase proteins in the endoplasmic reticulum. J Biol Chem. 2009 Nov 27; 284(48):33623-33. Doolittle MH, Neher SB, Ben-Zeev O, Ling-Liao J, Gallagher CM, Hosseini M, Yin F, Wong H, Walter P, Péterfy M. PMID: 19783858; PMCID: PMC2785204.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    149. Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. J Cell Biol. 2009 Aug 10; 186(3):323-31. Hollien J, Lin JH, Li H, Stevens N, Walter P, Weissman JS. PMID: 19651891; PMCID: PMC2728407.
      View in: PubMed   Mentions: 502     Fields:    Translation:AnimalsCells
    150. A genome-wide screen for genes affecting eisosomes reveals Nce102 function in sphingolipid signaling. J Cell Biol. 2009 Jun 29; 185(7):1227-42. Fröhlich F, Moreira K, Aguilar PS, Hubner NC, Mann M, Walter P, Walther TC. PMID: 19564405; PMCID: PMC2712959.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    151. An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science. 2009 Jul 24; 325(5939):477-81. Kornmann B, Currie E, Collins SR, Schuldiner M, Nunnari J, Weissman JS, Walter P. PMID: 19556461; PMCID: PMC2933203.
      View in: PubMed   Mentions: 621     Fields:    Translation:AnimalsCells
    152. The unfolded protein response during prostate cancer development. Cancer Metastasis Rev. 2009 Jun; 28(1-2):219-23. So AY, de la Fuente E, Walter P, Shuman M, Bernales S. PMID: 19172382.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    153. Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science. 2009 Mar 27; 323(5922):1693-7. Jonikas MC, Collins SR, Denic V, Oh E, Quan EM, Schmid V, Weibezahn J, Schwappach B, Walter P, Weissman JS, Schuldiner M. PMID: 19325107; PMCID: PMC2877488.
      View in: PubMed   Mentions: 385     Fields:    Translation:AnimalsCells
    154. BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha. Mol Cell. 2009 Mar 27; 33(6):679-91. Lisbona F, Rojas-Rivera D, Thielen P, Zamorano S, Todd D, Martinon F, Glavic A, Kress C, Lin JH, Walter P, Reed JC, Glimcher LH, Hetz C. PMID: 19328063; PMCID: PMC2818874.
      View in: PubMed   Mentions: 171     Fields:    Translation:HumansAnimalsCells
    155. Divergent effects of PERK and IRE1 signaling on cell viability. PLoS One. 2009; 4(1):e4170. Lin JH, Li H, Zhang Y, Ron D, Walter P. PMID: 19137072; PMCID: PMC2614882.
      View in: PubMed   Mentions: 157     Fields:    Translation:HumansCells
    156. Signal sequences activate the catalytic switch of SRP RNA. Science. 2009 Jan 02; 323(5910):127-30. Bradshaw N, Neher SB, Booth DS, Walter P. PMID: 19119234; PMCID: PMC2767340.
      View in: PubMed   Mentions: 47     Fields:    Translation:Cells
    157. Messenger RNA targeting to endoplasmic reticulum stress signalling sites. Nature. 2009 Feb 05; 457(7230):736-40. Aragón T, van Anken E, Pincus D, Serafimova IM, Korennykh AV, Rubio CA, Walter P. PMID: 19079237; PMCID: PMC2768538.
      View in: PubMed   Mentions: 163     Fields:    Translation:AnimalsCells
    158. The unfolded protein response signals through high-order assembly of Ire1. Nature. 2009 Feb 05; 457(7230):687-93. Korennykh AV, Egea PF, Korostelev AA, Finer-Moore J, Zhang C, Shokat KM, Stroud RM, Walter P. PMID: 19079236; PMCID: PMC2846394.
      View in: PubMed   Mentions: 338     Fields:    Translation:AnimalsCells
    159. Pil1 controls eisosome biogenesis. Mol Biol Cell. 2009 Feb; 20(3):809-18. Moreira KE, Walther TC, Aguilar PS, Walter P. PMID: 19037108; PMCID: PMC2633383.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    160. Targeting Hsp70 in Multiple Myeloma Induces Synergistic Cytotoxicity with Inhibitors of the Proteasome and of Hsp90. Blood. 2008 Nov 16; 112(11):5160-5160. Braunstein BM, Scott SC, Behrman BS, Walter WP, Wipf WP, Smith SE, Scott SS, Klueppelberg KH, Brodsky BJ, Batuman BO. .
      View in: Publisher Site   Mentions:
    161. Structures of the signal recognition particle receptor from the archaeon Pyrococcus furiosus: implications for the targeting step at the membrane. PLoS One. 2008; 3(11):e3619. Egea PF, Tsuruta H, de Leon GP, Napetschnig J, Walter P, Stroud RM. PMID: 18978942; PMCID: PMC2572998.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    162. Structures of SRP54 and SRP19, the two proteins that organize the ribonucleic core of the signal recognition particle from Pyrococcus furiosus. PLoS One. 2008; 3(10):e3528. Egea PF, Napetschnig J, Walter P, Stroud RM. PMID: 18953414; PMCID: PMC2568955.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    163. The in vitro and in vivo behaviour of retinal pigment epithelial cells cultured on ultrathin collagen membranes. Biomaterials. 2009 Jan; 30(3):287-94. Thumann G, Viethen A, Gaebler A, Walter P, Kaempf S, Johnen S, Salz AK. PMID: 18929407.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    164. Membrane lysis during biological membrane fusion: collateral damage by misregulated fusion machines. J Cell Biol. 2008 Oct 20; 183(2):181-6. Engel A, Walter P. PMID: 18852300; PMCID: PMC2568015.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    165. SRP RNA controls a conformational switch regulating the SRP-SRP receptor interaction. Nat Struct Mol Biol. 2008 Sep; 15(9):916-23. Neher SB, Bradshaw N, Floor SN, Gross JD, Walter P. PMID: 19172744; PMCID: PMC2767265.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    166. Helenius et al. reply. Nature. 2008 Jul 1; 454(7204):e4-e5. Helenius HJ, Ng ND, Marolda MC, Walter WP, Valvano VM, Aebi AM. .
      View in: Publisher Site   Mentions:
    167. Functional genomic screen reveals genes involved in lipid-droplet formation and utilization. Nature. 2008 May 29; 453(7195):657-61. Guo Y, Walther TC, Rao M, Stuurman N, Goshima G, Terayama K, Wong JS, Vale RD, Walter P, Farese RV. PMID: 18408709; PMCID: PMC2734507.
      View in: PubMed   Mentions: 334     Fields:    Translation:AnimalsCells
    168. Endoplasmic reticulum stress in disease pathogenesis. Annu Rev Pathol. 2008; 3:399-425. Lin JH, Walter P, Yen TS. PMID: 18039139; PMCID: PMC3653419.
      View in: PubMed   Mentions: 369     Fields:    Translation:HumansAnimalsCells
    169. Pkh-kinases control eisosome assembly and organization. EMBO J. 2007 Dec 12; 26(24):4946-55. Walther TC, Aguilar PS, Fröhlich F, Chu F, Moreira K, Burlingame AL, Walter P. PMID: 18034155; PMCID: PMC2094096.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    170. In Vitro Antimyeloma Effects of Inhibitors of the Heat Shock Protein 70 (Hsp70) Molecular Chaperone. Blood. 2007 Nov 16; 110(11):1524-1524. Braunstein BM, Scott SC, Berman BS, Walter WP, Wipf WP, Brodsky BJ, Batuman BO. .
      View in: Publisher Site   Mentions:
    171. IRE1 signaling affects cell fate during the unfolded protein response. Science. 2007 Nov 09; 318(5852):944-9. Lin JH, Li H, Yasumura D, Cohen HR, Zhang C, Panning B, Shokat KM, Lavail MM, Walter P. PMID: 17991856; PMCID: PMC3670588.
      View in: PubMed   Mentions: 730     Fields:    Translation:HumansAnimalsCells
    172. Identification of yeast proteins necessary for cell-surface function of a potassium channel. Proc Natl Acad Sci U S A. 2007 Nov 13; 104(46):18079-84. Haass FA, Jonikas M, Walter P, Weissman JS, Jan YN, Jan LY, Schuldiner M. PMID: 17989219; PMCID: PMC2084299.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    173. Conformational changes in the GTPase modules of the signal reception particle and its receptor drive initiation of protein translocation. J Cell Biol. 2007 Aug 13; 178(4):611-20. Shan SO, Chandrasekar S, Walter P. PMID: 17682051; PMCID: PMC2064468.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    174. X-ray structures of the signal recognition particle receptor reveal targeting cycle intermediates. PLoS One. 2007 Jul 11; 2(7):e607. Reyes CL, Rutenber E, Walter P, Stroud RM. PMID: 17622352; PMCID: PMC1904258.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    175. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol. 2007 Jul; 8(7):519-29. Ron D, Walter P. PMID: 17565364.
      View in: PubMed   Mentions: 3035     Fields:    Translation:HumansAnimalsCells
    176. The signal recognition particle (SRP) RNA links conformational changes in the SRP to protein targeting. Mol Biol Cell. 2007 Jul; 18(7):2728-34. Bradshaw N, Walter P. PMID: 17507650; PMCID: PMC1924838.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    177. ER-phagy: selective autophagy of the endoplasmic reticulum. Autophagy. 2007 May-Jun; 3(3):285-7. Bernales S, Schuck S, Walter P. PMID: 17351330.
      View in: PubMed   Mentions: 165     Fields:    Translation:AnimalsCells
    178. The Golgi-resident protease Kex2 acts in conjunction with Prm1 to facilitate cell fusion during yeast mating. J Cell Biol. 2007 Jan 15; 176(2):209-22. Heiman MG, Engel A, Walter P. PMID: 17210951; PMCID: PMC2063940.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    179. The plasma membrane proteins Prm1 and Fig1 ascertain fidelity of membrane fusion during yeast mating. Mol Biol Cell. 2007 Feb; 18(2):547-56. Aguilar PS, Engel A, Walter P. PMID: 17151357; PMCID: PMC1783792.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    180. Differential Effects of Hsp70 Inhibition within the Tumor and Microenvironment in Multiple Myeloma. Blood. 2006 Nov 16; 108(11):5070-5070. Braunstein BM, Liu LN, Klueppelberg KU, Scott SC, Behrman BS, Tamucin TC, Walter WP, Wipf WP, Brodsky BJ, Batuman BO. .
      View in: Publisher Site   Mentions:
    181. Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response. PLoS Biol. 2006 Nov; 4(12):e423. Bernales S, McDonald KL, Walter P. PMID: 17132049; PMCID: PMC1661684.
      View in: PubMed   Mentions: 476     Fields:    Translation:AnimalsCells
    182. Eisosomes mark static sites of endocytosis. Nature. 2006 Feb 23; 439(7079):998-1003. Walther TC, Brickner JH, Aguilar PS, Bernales S, Pantoja C, Walter P. PMID: 16496001.
      View in: PubMed   Mentions: 171     Fields:    Translation:AnimalsCells
    183. Intracellular signaling by the unfolded protein response. Annu Rev Cell Dev Biol. 2006; 22:487-508. Bernales S, Papa FR, Walter P. PMID: 16822172.
      View in: PubMed   Mentions: 280     Fields:    Translation:AnimalsCells
    184. On the mechanism of sensing unfolded protein in the endoplasmic reticulum. Proc Natl Acad Sci U S A. 2005 Dec 27; 102(52):18773-84. Credle JJ, Finer-Moore JS, Papa FR, Stroud RM, Walter P. PMID: 16365312; PMCID: PMC1316886.
      View in: PubMed   Mentions: 252     Fields:    Translation:HumansAnimalsCells
    185. Structural basis of FFAT motif-mediated ER targeting. Structure. 2005 Jul; 13(7):1035-45. Kaiser SE, Brickner JH, Reilein AR, Fenn TD, Walter P, Brunger AT. PMID: 16004875.
      View in: PubMed   Mentions: 111     Fields:    Translation:AnimalsCells
    186. Molecular Crosstalk between the Nucleotide Specificity Determinant of the SRP GTPase and the SRP Receptor. Biochemistry. 2005 May 1; 44(20):7602-7602. Shan SS, Walter WP. .
      View in: Publisher Site   Mentions:
    187. Molecular crosstalk between the nucleotide specificity determinant of the SRP GTPase and the SRP receptor. Biochemistry. 2005 Apr 26; 44(16):6214-22. Shan SO, Walter P. PMID: 15835909.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    188. Targeting proteins to membranes: structure of the signal recognition particle. Curr Opin Struct Biol. 2005 Apr; 15(2):213-20. Egea PF, Stroud RM, Walter P. PMID: 15837181.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimalsCells
    189. Co-translational protein targeting by the signal recognition particle. FEBS Lett. 2005 Feb 07; 579(4):921-6. Shan SO, Walter P. PMID: 15680975.
      View in: PubMed   Mentions: 49     Fields:    Translation:Cells
    190. Genome-scale approaches for discovering novel nonconventional splicing substrates of the Ire1 nuclease. Genome Biol. 2005; 6(1):R3. Niwa M, Patil CK, DeRisi J, Walter P. PMID: 15642095; PMCID: PMC549064.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    191. Unraveling the interface of signal recognition particle and its receptor by using chemical cross-linking and tandem mass spectrometry. Proc Natl Acad Sci U S A. 2004 Nov 23; 101(47):16454-9. Chu F, Shan SO, Moustakas DT, Alber F, Egea PF, Stroud RM, Walter P, Burlingame AL. PMID: 15546976; PMCID: PMC528904.
      View in: PubMed   Mentions: 36     Fields:    Translation:Cells
    192. Gene recruitment of the activated INO1 locus to the nuclear membrane. PLoS Biol. 2004 Nov; 2(11):e342. Brickner JH, Walter P. PMID: 15455074; PMCID: PMC519002.
      View in: PubMed   Mentions: 198     Fields:    Translation:AnimalsCells
    193. Mechanism of association and reciprocal activation of two GTPases. PLoS Biol. 2004 Oct; 2(10):e320. Shan SO, Stroud RM, Walter P. PMID: 15383838; PMCID: PMC517823.
      View in: PubMed   Mentions: 58     Fields:    Translation:Cells
    194. IRE1-independent gain control of the unfolded protein response. PLoS Biol. 2004 Aug; 2(8):E235. Leber JH, Bernales S, Walter P. PMID: 15314654; PMCID: PMC509300.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    195. Gcn4p and novel upstream activating sequences regulate targets of the unfolded protein response. PLoS Biol. 2004 Aug; 2(8):E246. Patil CK, Li H, Walter P. PMID: 15314660; PMCID: PMC509306.
      View in: PubMed   Mentions: 76     Fields:    Translation:AnimalsCells
    196. Substrate twinning activates the signal recognition particle and its receptor. Nature. 2004 Jan 15; 427(6971):215-21. Egea PF, Shan SO, Napetschnig J, Savage DF, Walter P, Stroud RM. PMID: 14724630.
      View in: PubMed   Mentions: 137     Fields:    Translation:Cells
    197. Bypassing a kinase activity with an ATP-competitive drug. Science. 2003 Nov 28; 302(5650):1533-7. Papa FR, Zhang C, Shokat K, Walter P. PMID: 14564015.
      View in: PubMed   Mentions: 114     Fields:    Translation:Cells
    198. Induced nucleotide specificity in a GTPase. Proc Natl Acad Sci U S A. 2003 Apr 15; 100(8):4480-5. Shan SO, Walter P. PMID: 12663860; PMCID: PMC153581.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    199. Structural basis for mobility in the 1.1 A crystal structure of the NG domain of Thermus aquaticus Ffh. J Mol Biol. 2002 Jul 19; 320(4):783-99. Ramirez UD, Minasov G, Focia PJ, Stroud RM, Walter P, Kuhn P, Freymann DM. PMID: 12095255; PMCID: PMC3542393.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    200. Translocation of lipid-linked oligosaccharides across the ER membrane requires Rft1 protein. Nature. 2002 Jan 24; 415(6870):447-50. Helenius J, Ng DT, Marolda CL, Walter P, Valvano MA, Aebi M. PMID: 11807558.
      View in: PubMed   Mentions: 87     Fields:    Translation:Cells
    201. 8 The Unfolded Protein Response. Protein Targeting, Transport, and Translocation. 2002 Jan 1; (Proc Natl Acad Sci USA921995):151-179. Sidrauski SC, Brickner BJ, Walter WP. .
      View in: Publisher Site   Mentions:
    202. Role of SRP RNA in the GTPase cycles of Ffh and FtsY. Biochemistry. 2001 Dec 18; 40(50):15224-33. Peluso P, Shan SO, Nock S, Herschlag D, Walter P. PMID: 11735405.
      View in: PubMed   Mentions: 80     Fields:    Translation:Cells
    203. Crystal structures of coaxially stacked kissing complexes of the HIV-1 RNA dimerization initiation site. Nat Struct Biol. 2001 Dec; 8(12):1064-8. Ennifar E, Walter P, Ehresmann B, Ehresmann C, Dumas P. PMID: 11702070.
      View in: PubMed   Mentions: 97     Fields:    Translation:Cells
    204. Yeast cytoplasmic and mitochondrial methionyl-tRNA synthetases: two structural frameworks for identical functions. J Mol Biol. 2001 Aug 03; 311(1):205-16. Senger B, Despons L, Walter P, Jakubowski H, Fasiolo F. PMID: 11469869.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    205. Intracellular signaling from the endoplasmic reticulum to the nucleus: the unfolded protein response in yeast and mammals. Curr Opin Cell Biol. 2001 Jun; 13(3):349-55. Patil C, Walter P. PMID: 11343907.
      View in: PubMed   Mentions: 262     Fields:    Translation:HumansAnimalsCells
    206. Multifaceted physiological response allows yeast to adapt to the loss of the signal recognition particle-dependent protein-targeting pathway. Mol Biol Cell. 2001 Mar; 12(3):577-88. Mutka SC, Walter P. PMID: 11251072; PMCID: PMC30965.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    207. Basis for regulated RNA cleavage by functional analysis of RNase L and Ire1p. RNA. 2001 Mar; 7(3):361-73. Dong B, Niwa M, Walter P, Silverman RH. PMID: 11333017; PMCID: PMC1370093.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    208. Ire1p: a kinase and site-specific endoribonuclease. Methods Mol Biol. 2001; 160:25-36. Gonzalez TN, Walter P. PMID: 11265288.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    209. Pausing to decide. Proc Natl Acad Sci U S A. 2000 Nov 07; 97(23):12396-7. Niwa M, Walter P. PMID: 11058174; PMCID: PMC34056.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    210. Prm1p, a pheromone-regulated multispanning membrane protein, facilitates plasma membrane fusion during yeast mating. J Cell Biol. 2000 Oct 30; 151(3):719-30. Heiman MG, Walter P. PMID: 11062271; PMCID: PMC2185589.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    211. The unfolded protein response regulates multiple aspects of secretory and membrane protein biogenesis and endoplasmic reticulum quality control. J Cell Biol. 2000 Jul 10; 150(1):77-88. Ng DT, Spear ED, Walter P. PMID: 10893258; PMCID: PMC2185565.
      View in: PubMed   Mentions: 131     Fields:    Translation:AnimalsCells
    212. Role of 4.5S RNA in assembly of the bacterial signal recognition particle with its receptor. Science. 2000 Jun 02; 288(5471):1640-3. Peluso P, Herschlag D, Nock S, Freymann DM, Johnson AE, Walter P. PMID: 10834842.
      View in: PubMed   Mentions: 76     Fields:    Translation:Cells
    213. Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation. Cell. 2000 Apr 28; 101(3):249-58. Travers KJ, Patil CK, Wodicka L, Lockhart DJ, Weissman JS, Walter P. PMID: 10847680.
      View in: PubMed   Mentions: 826     Fields:    Translation:AnimalsCells
    214. Perspectives: structural biology. SRP--where the RNA and membrane worlds meet. Science. 2000 Feb 18; 287(5456):1212-3. Walter P, Keenan R, Schmitz U. PMID: 10712156.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    215. A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response. Cell. 1999 Dec 23; 99(7):691-702. Niwa M, Sidrauski C, Kaufman RJ, Walter P. PMID: 10619423.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    216. Blobel's nobel: a vision validated. Cell. 1999 Dec 10; 99(6):557-8. Anderson D, Walter P. PMID: 10612390.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    217. Signal sequence recognition and protein targeting. Curr Opin Struct Biol. 1999 Dec; 9(6):754-9. Stroud RM, Walter P. PMID: 10607673.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    218. The crystal structure of the dimerization initiation site of genomic HIV-1 RNA reveals an extended duplex with two adenine bulges. Structure. 1999 Nov 15; 7(11):1439-49. Ennifar E, Yusupov M, Walter P, Marquet R, Ehresmann B, Ehresmann C, Dumas P. PMID: 10574792.
      View in: PubMed   Mentions: 63     Fields:    Translation:Cells
    219. Structure of the phylogenetically most conserved domain of SRP RNA. RNA. 1999 Nov; 5(11):1419-29. Schmitz U, Behrens S, Freymann DM, Keenan RJ, Lukavsky P, Walter P, James TL. PMID: 10580470; PMCID: PMC1369863.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    220. Functional changes in the structure of the SRP GTPase on binding GDP and Mg2+GDP. Nat Struct Biol. 1999 Aug; 6(8):793-801. Freymann DM, Keenan RJ, Stroud RM, Walter P. PMID: 10426959.
      View in: PubMed   Mentions: 38     Fields:    Translation:Cells
    221. Structure of the most conserved internal loop in SRP RNA. Nat Struct Biol. 1999 Jul; 6(7):634-8. Schmitz U, James TL, Lukavsky P, Walter P. PMID: 10404218.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    222. Mechanism of non-spliceosomal mRNA splicing in the unfolded protein response pathway. EMBO J. 1999 Jun 01; 18(11):3119-32. Gonzalez TN, Sidrauski C, Dörfler S, Walter P. PMID: 10357823; PMCID: PMC1171393.
      View in: PubMed   Mentions: 103     Fields:    Translation:AnimalsCells
    223. Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae. Mol Biol Cell. 1999 Apr; 10(4):987-1000. Powers T, Walter P. PMID: 10198052; PMCID: PMC25225.
      View in: PubMed   Mentions: 192     Fields:    Translation:AnimalsCells
    224. Two endoplasmic reticulum (ER) membrane proteins that facilitate ER-to-Golgi transport of glycosylphosphatidylinositol-anchored proteins. Mol Biol Cell. 1999 Apr; 10(4):1043-59. Barz WP, Walter P. PMID: 10198056; PMCID: PMC25232.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    225. Neisseria gonorrhoeae PilA is an FtsY homolog. J Bacteriol. 1999 Feb; 181(3):731-9. Arvidson CG, Powers T, Walter P, So M. PMID: 9922234; PMCID: PMC93437.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    226. Crystallization of the dimerization-initiation site of genomic HIV-1 RNA: preliminary crystallographic results. Acta Crystallogr D Biol Crystallogr. 1999 Jan; 55(Pt 1):281-4. Yusupov M, Walter P, Marquet R, Ehresmann C, Ehresmann B, Dumas P. PMID: 10089425.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    227. A functional GTPase domain, but not its transmembrane domain, is required for function of the SRP receptor beta-subunit. J Cell Biol. 1998 Jul 27; 142(2):341-54. Ogg SC, Barz WP, Walter P. PMID: 9679135; PMCID: PMC2133050.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    228. Crystal structure of the signal sequence binding subunit of the signal recognition particle. Cell. 1998 Jul 24; 94(2):181-91. Keenan RJ, Freymann DM, Walter P, Stroud RM. PMID: 9695947.
      View in: PubMed   Mentions: 108     Fields:    Translation:Cells
    229. The unfolded protein response: an intracellular signalling pathway with many surprising features. Trends Cell Biol. 1998 Jun; 8(6):245-9. Sidrauski C, Chapman R, Walter P. PMID: 9695849.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    230. Heterodimer SRP9/14 is an integral part of the neural BC200 RNP in primate brain. Neurosci Lett. 1998 Apr 10; 245(3):123-6. Kremerskothen J, Zopf D, Walter P, Cheng JG, Nettermann M, Niewerth U, Maraia RJ, Brosius J. PMID: 9605471.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    231. Intracellular signaling from the endoplasmic reticulum to the nucleus. Annu Rev Cell Dev Biol. 1998; 14:459-85. Chapman R, Sidrauski C, Walter P. PMID: 9891790.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    232. A ribosome at the end of the tunnel. Science. 1997 Dec 19; 278(5346):2072-3. Powers T, Walter P. PMID: 9432719.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    233. Translational attenuation mediated by an mRNA intron. Curr Biol. 1997 Nov 01; 7(11):850-9. Chapman RE, Walter P. PMID: 9382810.
      View in: PubMed   Mentions: 70     Fields:    Translation:AnimalsCells
    234. The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response. Cell. 1997 Sep 19; 90(6):1031-9. Sidrauski C, Walter P. PMID: 9323131.
      View in: PubMed   Mentions: 389     Fields:    Translation:AnimalsCells
    235. The unfolded protein response coordinates the production of endoplasmic reticulum protein and endoplasmic reticulum membrane. Mol Biol Cell. 1997 Sep; 8(9):1805-14. Cox JS, Chapman RE, Walter P. PMID: 9307975; PMCID: PMC305738.
      View in: PubMed   Mentions: 180     Fields:    Translation:AnimalsCells
    236. Co-translational protein targeting catalyzed by the Escherichia coli signal recognition particle and its receptor. EMBO J. 1997 Aug 15; 16(16):4880-6. Powers T, Walter P. PMID: 9305630; PMCID: PMC1170123.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    237. Mitochondrial transmission during mating in Saccharomyces cerevisiae is determined by mitochondrial fusion and fission and the intramitochondrial segregation of mitochondrial DNA. Mol Biol Cell. 1997 Jul; 8(7):1233-42. Nunnari J, Marshall WF, Straight A, Murray A, Sedat JW, Walter P. PMID: 9243504; PMCID: PMC276149.
      View in: PubMed   Mentions: 194     Fields:    Translation:AnimalsCells
    238. Structure of the conserved GTPase domain of the signal recognition particle. Nature. 1997 Jan 23; 385(6614):361-4. Freymann DM, Keenan RJ, Stroud RM, Walter P. PMID: 9002524.
      View in: PubMed   Mentions: 89     Fields:    Translation:Cells
    239. NMR studies of the most conserved RNA domain of the mammalian signal recognition particle (SRP). RNA. 1996 Dec; 2(12):1213-27. Schmitz U, Freymann DM, James TL, Keenan RJ, Vinayak R, Walter P. PMID: 8972771; PMCID: PMC1369449.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    240. A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response. Cell. 1996 Nov 01; 87(3):391-404. Cox JS, Walter P. PMID: 8898193.
      View in: PubMed   Mentions: 450     Fields:    Translation:AnimalsCells
    241. tRNA ligase is required for regulated mRNA splicing in the unfolded protein response. Cell. 1996 Nov 01; 87(3):405-13. Sidrauski C, Cox JS, Walter P. PMID: 8898194.
      View in: PubMed   Mentions: 195     Fields:    Translation:AnimalsCells
    242. Progress torwards the crystal structure of Ffh, the bacterial homolog of SRP54. Acta Crystallographica Section A: Foundations and advances. 1996 Aug 8; 52(a1):c167-c167. Freymann FD, Keenan KR, Stroud SR, Walter WP. .
      View in: Publisher Site   Mentions:
    243. Signal sequences specify the targeting route to the endoplasmic reticulum membrane. J Cell Biol. 1996 Jul; 134(2):269-78. Ng DT, Brown JD, Walter P. PMID: 8707814; PMCID: PMC2120870.
      View in: PubMed   Mentions: 174     Fields:    Translation:AnimalsCells
    244. Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus. EMBO J. 1996 Jun 17; 15(12):3028-39. Shamu CE, Walter P. PMID: 8670804; PMCID: PMC450244.
      View in: PubMed   Mentions: 254     Fields:    Translation:AnimalsCells
    245. Protein targeting. The ribosome talks back. Nature. 1996 May 16; 381(6579):191-2. Powers T, Walter P. PMID: 8622754.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    246. The nascent polypeptide-associated complex modulates interactions between the signal recognition particle and the ribosome. Curr Biol. 1996 Mar 01; 6(3):331-8. Powers T, Walter P. PMID: 8805251.
      View in: PubMed   Mentions: 37     Fields:    Translation:Cells
    247. Regulation of organelle biogenesis. Cell. 1996 Feb 09; 84(3):389-94. Nunnari J, Walter P. PMID: 8608592.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    248. ER membrane protein complex required for nuclear fusion. J Cell Biol. 1996 Feb; 132(4):499-509. Ng DT, Walter P. PMID: 8647883; PMCID: PMC2199862.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    249. Conservation in evolution for a small monomeric phenylalanyl-tRNA synthetase of the tRNA(Phe) recognition nucleotides and initial aminoacylation site. Biochemistry. 1996 Jan 09; 35(1):117-23. Aphasizhev R, Senger B, Rengers JU, Sprinzl M, Walter P, Nussbaum G, Fasiolo F. PMID: 8555164.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    250. Reciprocal stimulation of GTP hydrolysis by two directly interacting GTPases. Science. 1995 Sep 08; 269(5229):1422-4. Powers T, Walter P. PMID: 7660124.
      View in: PubMed   Mentions: 66     Fields:    Translation:Cells
    251. An amino-terminal domain containing hydrophobic and hydrophilic sequences binds the signal recognition particle receptor alpha subunit to the beta subunit on the endoplasmic reticulum membrane. J Biol Chem. 1995 Jun 30; 270(26):15650-7. Young JC, Ursini J, Legate KR, Miller JD, Walter P, Andrews DW. PMID: 7797564.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    252. SRP samples nascent chains for the presence of signal sequences by interacting with ribosomes at a discrete step during translation elongation. Cell. 1995 Jun 30; 81(7):1075-84. Ogg SC, Walter P. PMID: 7600575.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    253. The 70 carboxyl-terminal amino acids of nascent secretory proteins are protected from proteolysis by the ribosome and the protein translocation apparatus of the endoplasmic reticulum membrane. J Biol Chem. 1995 Mar 17; 270(11):6170-80. Matlack KE, Walter P. PMID: 7890751.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    254. The beta subunit of the signal recognition particle receptor is a transmembrane GTPase that anchors the alpha subunit, a peripheral membrane GTPase, to the endoplasmic reticulum membrane. J Cell Biol. 1995 Feb; 128(3):273-82. Miller JD, Tajima S, Lauffer L, Walter P. PMID: 7844142; PMCID: PMC2120348.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    255. Signal sequence recognition and protein targeting to the endoplasmic reticulum membrane. Harvey Lect. 1995-1996; 91:115-31. Walter P. PMID: 9127989.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    256. Targeting pathways to the endoplasmic reticulum membrane. Cold Spring Harb Symp Quant Biol. 1995; 60:23-30. Brown JD, NG DT, Ogg SC, Walter P. PMID: 8824374.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    257. Subunits of the Saccharomyces cerevisiae signal recognition particle required for its functional expression. EMBO J. 1994 Sep 15; 13(18):4390-400. Brown JD, Hann BC, Medzihradszky KF, Niwa M, Burlingame AL, Walter P. PMID: 7925282; PMCID: PMC395366.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    258. Protein translocation across the endoplasmic reticulum. Curr Opin Cell Biol. 1994 Aug; 6(4):510-6. Ng DT, Walter P. PMID: 7986526.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    259. Genetic and biochemical analysis of the fission yeast ribonucleoprotein particle containing a homolog of Srp54p. Nucleic Acids Res. 1994 Jul 11; 22(13):2557-67. Selinger D, Brennwald P, Althoff S, Reich C, Hann B, Walter P, Wise JA. PMID: 8041618; PMCID: PMC308210.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    260. Interaction of E. coli Ffh/4.5S ribonucleoprotein and FtsY mimics that of mammalian signal recognition particle and its receptor. Nature. 1994 Feb 17; 367(6464):657-9. Miller JD, Bernstein HD, Walter P. PMID: 8107852.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    261. The unfolded-protein-response pathway in yeast. Trends Cell Biol. 1994 Feb; 4(2):56-60. Shamu CE, Cox JS, Walter P. PMID: 14731868.
      View in: PubMed   Mentions: 48     Fields:    
    262. Role of the histone amino termini in facilitated binding of a transcription factor, GAL4-AH, to nucleosome cores. Mol Cell Biol. 1994 Feb; 14(2):970-81. Vettese-Dadey M, Walter P, Chen H, Juan LJ, Workman JL. PMID: 8289837; PMCID: PMC358452.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    263. [Noninvasive studies of macro- and microcirculation in follow-up of femoropopliteal bypass operation in IIb peripheral arterial occlusive disease]. Vasa. 1994; 23(4):312-20. Scheffler P, Gross J, Dabringhaus S, de la Hamette D, Walter P. PMID: 7817611.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    264. Signal sequence recognition and protein targeting to the endoplasmic reticulum membrane. Annu Rev Cell Biol. 1994; 10:87-119. Walter P, Johnson AE. PMID: 7888184.
      View in: PubMed   Mentions: 259     Fields:    Translation:HumansCells
    265. A mitochondrial protease with two catalytic subunits of nonoverlapping specificities. Science. 1993 Dec 24; 262(5142):1997-2004. Nunnari J, Fox TD, Walter P. PMID: 8266095.
      View in: PubMed   Mentions: 86     Fields:    Translation:AnimalsCells
    266. GTP binding and hydrolysis by the signal recognition particle during initiation of protein translocation. Nature. 1993 Nov 25; 366(6453):351-4. Miller JD, Wilhelm H, Gierasch L, Gilmore R, Walter P. PMID: 8247130.
      View in: PubMed   Mentions: 54     Fields:    Translation:Cells
    267. Shedding light on the translocation pore. Curr Biol. 1993 Oct 01; 3(10):677-9. Matlack KE, Walter P. PMID: 15335859.
      View in: PubMed   Mentions:    Fields:    
    268. Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase. Cell. 1993 Jun 18; 73(6):1197-206. Cox JS, Shamu CE, Walter P. PMID: 8513503.
      View in: PubMed   Mentions: 566     Fields:    Translation:AnimalsCells
    269. Functional substitution of the signal recognition particle 54-kDa subunit by its Escherichia coli homolog. Proc Natl Acad Sci U S A. 1993 Jun 01; 90(11):5229-33. Bernstein HD, Zopf D, Freymann DM, Walter P. PMID: 8389475; PMCID: PMC46689.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    270. Discrete nascent chain lengths are required for the insertion of presecretory proteins into microsomal membranes. J Cell Biol. 1993 Jun; 121(6):1211-9. Wolin SL, Walter P. PMID: 8389768; PMCID: PMC2119713.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    271. GTPase domain of the 54-kD subunit of the mammalian signal recognition particle is required for protein translocation but not for signal sequence binding. J Cell Biol. 1993 Mar; 120(5):1113-21. Zopf D, Bernstein HD, Walter P. PMID: 8382204; PMCID: PMC2119734.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    272. A GTPase cycle in initiation of protein translocation across the endoplasmic reticulum membrane. Ciba Found Symp. 1993; 176:147-59; discussion 159-63. Miller JD, Walter P. PMID: 8299417.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    273. The SRP-Dependent Protein Targeting Pathway in Saccharomyces Cerevisiae. Protein Synthesis and Targeting in Yeast. 1993 Jan 1; 283-292. Walter WP, Ogg OS, Hann HB. .
      View in: Publisher Site   Mentions:
    274. Signal recognition particle receptor is important for cell growth and protein secretion in Saccharomyces cerevisiae. Mol Biol Cell. 1992 Aug; 3(8):895-911. Ogg SC, Poritz MA, Walter P. PMID: 1327299; PMCID: PMC275647.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    275. Protein targeting to and translocation across the membrane of the endoplasmic reticulum. Curr Opin Cell Biol. 1992 Aug; 4(4):573-80. Nunnari J, Walter P. PMID: 1419037.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    276. Fluorescence-detected assembly of the signal recognition particle: binding of the two SRP protein heterodimers to SRP RNA is noncooperative. Biochemistry. 1992 Jun 30; 31(25):5830-40. Janiak F, Walter P, Johnson AE. PMID: 1377027.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    277. Binding of the yeast tRNA(Met) anticodon by the cognate methionyl-tRNA synthetase involves at least two independent peptide regions. J Mol Biol. 1992 Jun 05; 225(3):897-907. Despons L, Senger B, Fasiolo F, Walter P. PMID: 1602489.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    278. Protein translocation. Travelling by TRAM. Nature. 1992 May 07; 357(6373):22-3. Walter P. PMID: 1315419.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    279. SEC65 gene product is a subunit of the yeast signal recognition particle required for its integrity. Nature. 1992 Apr 09; 356(6369):532-3. Hann BC, Stirling CJ, Walter P. PMID: 1313947.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    280. Mutants in three novel complementation groups inhibit membrane protein insertion into and soluble protein translocation across the endoplasmic reticulum membrane of Saccharomyces cerevisiae. J Cell Biol. 1992 Feb; 116(3):597-604. Green N, Fang H, Walter P. PMID: 1730771; PMCID: PMC2289319.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    281. C-terminal sequences can inhibit the insertion of membrane proteins into the endoplasmic reticulum of Saccharomyces cerevisiae. Mol Cell Biol. 1992 Jan; 12(1):276-82. Green N, Walter P. PMID: 1729604; PMCID: PMC364098.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    282. Chapter 11 The role of GTP in protein targeting to the endoplasmic reticulum. Membrane Biogenesis and Protein Targeting. 1992 Jan 1; 22:129-136. Ogg OS, Nunnari NJ, Miller MJ, Walter WP. .
      View in: Publisher Site   Mentions:
    283. C-terminal sequences can inhibit the insertion of membrane proteins into the endoplasmic reticulum of Saccharomyces cerevisiae. Molecular and Cellular Biology. 1992 Jan 1; 12(1):276-282. Green GN, Walter WP. .
      View in: Publisher Site   Mentions:
    284. C-Terminal Sequences Can Inhibit the Insertion of Membrane Proteins into the Endoplasmic Reticulum of Saccharomyces cerevisiae. Molecular and Cellular Biology. 1992 Jan 1; 12(1):276-282. Green GN, Walter WP. .
      View in: Publisher Site   Mentions:
    285. Characterization of the rough endoplasmic reticulum ribosome-binding activity. Trends in Cell Biology. 1991 Nov 1; 1(5):115. Nunnari NJ, Zimmerman ZD, Ogg OS, Walter WP. .
      View in: Publisher Site   Mentions:
    286. The signal recognition particle in S. cerevisiae. Cell. 1991 Oct 04; 67(1):131-44. Hann BC, Walter P. PMID: 1655273.
      View in: PubMed   Mentions: 113     Fields:    Translation:Animals
    287. An ATP-binding membrane protein is required for protein translocation across the endoplasmic reticulum membrane. Cell Regul. 1991 Oct; 2(10):851-9. Zimmerman DL, Walter P. PMID: 1801920; PMCID: PMC361880.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    288. Evolution of aminoacyl-tRNA synthetase quaternary structure and activity: Saccharomyces cerevisiae mitochondrial phenylalanyl-tRNA synthetase. Proc Natl Acad Sci U S A. 1991 Oct 01; 88(19):8387-91. Sanni A, Walter P, Boulanger Y, Ebel JP, Fasiolo F. PMID: 1924298; PMCID: PMC52513.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    289. Identification of potential amino acid residues supporting anticodon recognition in yeast methionyl-tRNA synthetase. FEBS Lett. 1991 Sep 09; 289(2):217-20. Despons L, Walter P, Senger B, Ebel JP, Fasiolo F. PMID: 1915850.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    290. Characterization of the rough endoplasmic reticulum ribosome-binding activity. Nature. 1991 Aug 15; 352(6336):638-40. Nunnari JM, Zimmerman DL, Ogg SC, Walter P. PMID: 1650916.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    291. Binding sites of the 9- and 14-kilodalton heterodimeric protein subunit of the signal recognition particle (SRP) are contained exclusively in the Alu domain of SRP RNA and contain a sequence motif that is conserved in evolution. Mol Cell Biol. 1991 Aug; 11(8):3949-59. Strub K, Moss J, Walter P. PMID: 1712900; PMCID: PMC361190.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    292. Binding Sites of the 9- and 14-Kilodalton Heterodimeric Protein Subunit of the Signal Recognition Particle (SRP) Are Contained Exclusively in the Alu Domain of SRP RNA and Contain a Sequence Motif That Is Conserved in Evolution. Molecular and Cellular Biology. 1991 Aug 1; 11(8):3949-3959. Strub SK, Moss MJ, Walter WP. .
      View in: Publisher Site   Mentions:
    293. Binding sites of the 9- and 14-kilodalton heterodimeric protein subunit of the signal recognition particle (SRP) are contained exclusively in the Alu domain of SRP RNA and contain a sequence motif that is conserved in evolution. Molecular and Cellular Biology. 1991 Aug 1; 11(8):3949-3959. Strub SK, Moss MJ, Walter WP. .
      View in: Publisher Site   Mentions:
    294. Small ribonucleoproteins. Current Opinion in Structural Biology. 1991 Apr 1; 1(2):251-257. Wolin WS, Walter WP. .
      View in: Publisher Site   Mentions:
    295. Response: "Sequence-Gazing?". Science. 1991 Mar 8; 251(4998):1161-1162. Poritz PM, Bernstein BH, Walter WP. .
      View in: Publisher Site   Mentions:
    296. Response: "Sequence-Gazing?". Science. 1991 Mar 8; 251(4998):1161-1162. Poritz PM, Bernstein BH, Walter WP. .
      View in: Publisher Site   Mentions:
    297. A nascent membrane protein is located adjacent to ER membrane proteins throughout its integration and translation. J Cell Biol. 1991 Mar; 112(5):809-21. Thrift RN, Andrews DW, Walter P, Johnson AE. PMID: 1999459; PMCID: PMC2288876.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    298. The methionine-rich domain of the 54 kd protein subunit of the signal recognition particle contains an RNA binding site and can be crosslinked to a signal sequence. EMBO J. 1990 Dec; 9(13):4511-7. Zopf D, Bernstein HD, Johnson AE, Walter P. PMID: 1702385; PMCID: PMC552245.
      View in: PubMed   Mentions: 84     Fields:    Translation:Cells
    299. An E. coli ribonucleoprotein containing 4.5S RNA resembles mammalian signal recognition particle. Science. 1990 Nov 23; 250(4984):1111-7. Poritz MA, Bernstein HD, Strub K, Zopf D, Wilhelm H, Walter P. PMID: 1701272.
      View in: PubMed   Mentions: 114     Fields:    Translation:Cells
    300. Yeast methionyl-tRNA synthetase: analysis of the N-terminal extension and the putative tRNA anticodon binding region by site-directed mutagenesis. Biochimie. 1990 Aug; 72(8):537-44. Walter P, Despons L, Laforet M, Ebel JP, Fasiolo F. PMID: 2126459.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    301. Reconstitution of protein translocation activity from partially solubilized microsomal vesicles. J Biol Chem. 1990 Mar 05; 265(7):4048-53. Zimmerman DL, Walter P. PMID: 2105958.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    302. Assembly of the Alu domain of the signal recognition particle (SRP): dimerization of the two protein components is required for efficient binding to SRP RNA. Mol Cell Biol. 1990 Feb; 10(2):777-84. Strub K, Walter P. PMID: 2153922; PMCID: PMC360878.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    303. Assembly of the Alu domain of the signal recognition particle (SRP): dimerization of the two protein components is required for efficient binding to SRP RNA. Molecular and Cellular Biology. 1990 Feb 1; 10(2):777-784. Strub SK, Walter WP. .
      View in: Publisher Site   Mentions:
    304. Assembly of the Alu Domain of the Signal Recognition Particle (SRP): Dimerization of the Two Protein Components Is Required for Efficient Binding to SRP RNA. Molecular and Cellular Biology. 1990 Feb 1; 10(2):777-784. Strub SK, Walter WP. .
      View in: Publisher Site   Mentions:
    305. Signal recognition particle mediates a transient elongation arrest of preprolactin in reticulocyte lysate. J Cell Biol. 1989 Dec; 109(6 Pt 1):2617-22. Wolin SL, Walter P. PMID: 2556403; PMCID: PMC2115964.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    306. Saccharomyces cerevisiae and Schizosaccharomyces pombe contain a homologue to the 54-kD subunit of the signal recognition particle that in S. cerevisiae is essential for growth. J Cell Biol. 1989 Dec; 109(6 Pt 2):3223-30. Hann BC, Poritz MA, Walter P. PMID: 2557350; PMCID: PMC2115968.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    307. Isolation of a cDNA clone of the 14-kDa subunit of the signal recognition particle by cross-hybridization of differently primed polymerase chain reactions. Proc Natl Acad Sci U S A. 1989 Dec; 86(24):9747-51. Strub K, Walter P. PMID: 2557625; PMCID: PMC298578.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    308. Protein translocation across the endoplasmic reticulum membrane: identification by photocross-linking of a 39-kD integral membrane glycoprotein as part of a putative translocation tunnel. J Cell Biol. 1989 Nov; 109(5):2033-43. Krieg UC, Johnson AE, Walter P. PMID: 2808520; PMCID: PMC2115841.
      View in: PubMed   Mentions: 46     Fields:    Translation:Cells
    309. Deletion analysis in the amino-terminal extension of methionyl-tRNA synthetase from Saccharomyces cerevisiae shows that a small region is important for the activity and stability of the enzyme. J Biol Chem. 1989 Oct 15; 264(29):17126-30. Walter P, Weygand-Durasevic I, Sanni A, Ebel JP, Fasiolo F. PMID: 2677000.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    310. Cytosolic protein translocation factors. Is SRP still unique? Cell. 1989 Sep 22; 58(6):1017-9. Bernstein HD, Rapoport TA, Walter P. PMID: 2550141.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    311. Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle. Nature. 1989 Aug 10; 340(6233):482-6. Bernstein HD, Poritz MA, Strub K, Hoben PJ, Brenner S, Walter P. PMID: 2502718.
      View in: PubMed   Mentions: 158     Fields:    Translation:AnimalsCells
    312. Assembly of proteins in the endoplasmic reticulum. Curr Opin Cell Biol. 1989 Aug; 1(4):635-8. Siegel V, Walter P. PMID: 2697275.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    313. Cassette mutagenic analysis of the yeast invertase signal peptide: effects on protein translocation. Mol Cell Biol. 1989 Aug; 9(8):3400-10. Ngsee JK, Hansen W, Walter P, Smith M. PMID: 2677671; PMCID: PMC362386.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    314. Cassette mutagenic analysis of the yeast invertase signal peptide: effects on protein translocation. Molecular and Cellular Biology. 1989 Aug 1; 9(8):3400-3410. Ngsee NJ, Hansen HW, Walter WP, Smith SM. .
      View in: Publisher Site   Mentions:
    315. Cassette Mutagenic Analysis of the Yeast Invertase Signal Peptide: Effects on Protein Translocation. Molecular and Cellular Biology. 1989 Aug 1; 9(8):3400-3410. Ngsee NJ, Hansen HW, Walter WP, Smith SM. .
      View in: Publisher Site   Mentions:
    316. Evidence for a two-step mechanism involved in assembly of functional signal recognition particle receptor. J Cell Biol. 1989 Mar; 108(3):797-810. Andrews DW, Lauffer L, Walter P, Lingappa VR. PMID: 2537835; PMCID: PMC2115407.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    317. The use of gene-fusions to determine membrane protein topology in Saccharomyces cerevisiae. J Cell Sci Suppl. 1989; 11:109-13. Green GN, Hansen W, Walter P. PMID: 2693456.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    318. Ribosome pausing and stacking during translation of a eukaryotic mRNA. EMBO J. 1988 Nov; 7(11):3559-69. Wolin SL, Walter P. PMID: 2850168; PMCID: PMC454858.
      View in: PubMed   Mentions: 227     Fields:    Translation:AnimalsCells
    319. Isolation and characterization of a cDNA clone encoding the 19 kDa protein of signal recognition particle (SRP): expression and binding to 7SL RNA. Nucleic Acids Res. 1988 Oct 25; 16(20):9431-42. Lingelbach K, Zwieb C, Webb JR, Marshallsay C, Hoben PJ, Walter P, Dobberstein B. PMID: 2460823; PMCID: PMC338754.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    320. Human SRP RNA and E. coli 4.5S RNA contain a highly homologous structural domain. Cell. 1988 Oct 07; 55(1):4-6. Poritz MA, Strub K, Walter P. PMID: 2458843.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    321. Functional dissection of the signal recognition particle. Trends Biochem Sci. 1988 Aug; 13(8):314-6. Siegel V, Walter P. PMID: 2856455.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    322. The affinity of signal recognition particle for presecretory proteins is dependent on nascent chain length. EMBO J. 1988 Jun; 7(6):1769-75. Siegel V, Walter P. PMID: 3169004; PMCID: PMC457167.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    323. Small ribonucleoproteins in Schizosaccharomyces pombe and Yarrowia lipolytica homologous to signal recognition particle. Proc Natl Acad Sci U S A. 1988 Jun; 85(12):4315-9. Poritz MA, Siegel V, Hansen W, Walter P. PMID: 2837764; PMCID: PMC280419.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    324. Heavy-chain binding protein recognizes aberrant polypeptides translocated in vitro. Nature. 1988 May 05; 333(6168):90-3. Kassenbrock CK, Garcia PD, Walter P, Kelly RB. PMID: 3129663.
      View in: PubMed   Mentions: 68     Fields:    Translation:Cells
    325. Prepro-carboxypeptidase Y and a truncated form of pre-invertase, but not full-length pre-invertase, can be posttranslationally translocated across microsomal vesicle membranes from Saccharomyces cerevisiae. J Cell Biol. 1988 Apr; 106(4):1075-81. Hansen W, Walter P. PMID: 3283144; PMCID: PMC2115026.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    326. Targeting of the hepatitis B virus precore protein to the endoplasmic reticulum membrane: after signal peptide cleavage translocation can be aborted and the product released into the cytoplasm. J Cell Biol. 1988 Apr; 106(4):1093-104. Garcia PD, Ou JH, Rutter WJ, Walter P. PMID: 3283145; PMCID: PMC2114996.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansCells
    327. Full-length prepro-alpha-factor can be translocated across the mammalian microsomal membrane only if translation has not terminated. J Cell Biol. 1988 Apr; 106(4):1043-8. Garcia PD, Walter P. PMID: 2834400; PMCID: PMC2115022.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    328. Binding sites of the 19-kDa and 68/72-kDa signal recognition particle (SRP) proteins on SRP RNA as determined in protein-RNA "footprinting". Proc Natl Acad Sci U S A. 1988 Mar; 85(6):1801-5. Siegel V, Walter P. PMID: 2450348; PMCID: PMC279867.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    329. Each of the activities of signal recognition particle (SRP) is contained within a distinct domain: analysis of biochemical mutants of SRP. Cell. 1988 Jan 15; 52(1):39-49. Siegel V, Walter P. PMID: 2830980.
      View in: PubMed   Mentions: 107     Fields:    Translation:AnimalsCells
    330. Evidence for an extended 7SL RNA structure in the signal recognition particle. EMBO J. 1987 Nov; 6(11):3471-7. Andrews DW, Walter P, Ottensmeyer FP. PMID: 2828031; PMCID: PMC553805.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    331. Substrate requirements for SRP-mediated targeting to the ER membrane. Molecular Biology Reports. 1987 Sep 1; 12(3):219-219. Siegel SV, Garcia GP, Walter WP. .
      View in: Publisher Site   Mentions:
    332. Functional dissection of the signal recognition particle. Molecular Biology Reports. 1987 Sep 1; 12(3):220-220. Siegel SV, Poritz PM, Walter WP. .
      View in: Publisher Site   Mentions:
    333. Signal recognition. Two receptors act sequentially. Nature. 1987 Aug 27-Sep 2; 328(6133):763-4. Walter P. PMID: 3041220.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    334. Wild type and mutant signal peptides of Escherichia coli outer membrane lipoprotein interact with equal efficiency with mammalian signal recognition particle. J Biol Chem. 1987 Jul 15; 262(20):9463-8. Garcia PD, Ghrayeb J, Inouye M, Walter P. PMID: 3298258.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    335. Mathematical modeling of the effects of the signal recognition particle on translation and translocation of proteins across the endoplasmic reticulum membrane. J Mol Biol. 1987 Jun 05; 195(3):621-36. Rapoport TA, Heinrich R, Walter P, Schulmeister T. PMID: 2821280.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    336. Photocrosslinking of the signal sequence of nascent preprolactin to the 54-kilodalton polypeptide of the signal recognition particle. Proc Natl Acad Sci U S A. 1986 Nov; 83(22):8604-8. Krieg UC, Walter P, Johnson AE. PMID: 3095839; PMCID: PMC386979.
      View in: PubMed   Mentions: 126     Fields:    Translation:Cells
    337. The signal recognition particle receptor is a complex that contains two distinct polypeptide chains. J Cell Biol. 1986 Oct; 103(4):1167-78. Tajima S, Lauffer L, Rath VL, Walter P. PMID: 3021779; PMCID: PMC2114348.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    338. In vitro protein translocation across the yeast endoplasmic reticulum: ATP-dependent posttranslational translocation of the prepro-alpha-factor. Cell. 1986 May 09; 45(3):397-406. Hansen W, Garcia PD, Walter P. PMID: 3009026.
      View in: PubMed   Mentions: 129     Fields:    Translation:AnimalsCells
    339. Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature. 1986 Mar 13-19; 320(6058):134-9. Green S, Walter P, Kumar V, Krust A, Bornert JM, Argos P, Chambon P. PMID: 3754034.
      View in: PubMed   Mentions: 470     Fields:    Translation:HumansCells
    340. Removal of the Alu structural domain from signal recognition particle leaves its protein translocation activity intact. Nature. 1986 Mar 6-12; 320(6057):81-4. Siegel V, Walter P. PMID: 2419765.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    341. Mechanism of protein translocation across the endoplasmic reticulum membrane. Annu Rev Cell Biol. 1986; 2:499-516. Walter P, Lingappa VR. PMID: 3030381.
      View in: PubMed   Mentions: 164     Fields:    Translation:AnimalsCells
    342. Structure and Function of the Signal Recognition Particle. Genetic Engineering. 1986 Jan 1; 181-196. Siegel SV, Walter WP. .
      View in: Publisher Site   Mentions:
    343. The Protein Translocation Machinery of the Endoplasmic Reticulum: The Signal Hypothesis Ten Years Later. Protein Compartmentalization. 1986 Jan 1; 1-13. Walter WP, Siegel SV, Lauffer LL, Garcia GP. .
      View in: Publisher Site   Mentions:
    344. Intracellular Protein Topogenesis. New Insights into Cell and Membrane Transport Processes. 1986 Jan 1; 277-283. Blobel BG, Walter WP, Gilmore GR. .
      View in: Publisher Site   Mentions:
    345. Topology of signal recognition particle receptor in endoplasmic reticulum membrane. Nature. 1985 Nov 28-Dec 4; 318(6044):334-8. Lauffer L, Garcia PD, Harkins RN, Coussens L, Ullrich A, Walter P. PMID: 2999608.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    346. Elongation arrest is not a prerequisite for secretory protein translocation across the microsomal membrane. J Cell Biol. 1985 Jun; 100(6):1913-21. Siegel V, Walter P. PMID: 2581979; PMCID: PMC2113602.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    347. Structure of the signal recognition particle by electron microscopy. Proc Natl Acad Sci U S A. 1985 Feb; 82(3):785-9. Andrews DW, Walter P, Ottensmeyer FP. PMID: 3856232; PMCID: PMC397131.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    348. Protein translocation across the endoplasmic reticulum. Cell. 1984 Aug; 38(1):5-8. Walter P, Gilmore R, Blobel G. PMID: 6088076.
      View in: PubMed   Mentions: 213     Fields:    Translation:AnimalsCells
    349. Role of signal recognition particle in the membrane assembly of Sindbis viral glycoproteins. Eur J Biochem. 1984 May 02; 140(3):499-502. Bonatti S, Migliaccio G, Blobel G, Walter P. PMID: 6723645.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    350. Subcellular distribution of signal recognition particle and 7SL-RNA determined with polypeptide-specific antibodies and complementary DNA probe. J Cell Biol. 1983 Dec; 97(6):1693-9. Walter P, Blobel G. PMID: 6196367; PMCID: PMC2112735.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    351. Disassembly and reconstitution of signal recognition particle. Cell. 1983 Sep; 34(2):525-33. Walter P, Blobel G. PMID: 6413076.
      View in: PubMed   Mentions: 99     Fields:    Translation:AnimalsCells
    352. Translocation of a lysosomal enzyme across the microsomal membrane requires signal recognition particle. Biochem Biophys Res Commun. 1983 Aug 30; 115(1):275-80. Erickson AH, Walter P, Blobel G. PMID: 6137219.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    353. Signal recognition particle: a ribonucleoprotein required for cotranslational translocation of proteins, isolation and properties. Methods Enzymol. 1983; 96:682-91. Walter P, Blobel G. PMID: 6197610.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    354. The protein translocation machinery of the endoplasmic reticulum. Philos Trans R Soc Lond B Biol Sci. 1982 Dec 24; 300(1099):225-8. Walter P, Gilmore R, Müller M, Blobel G. PMID: 6131460.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    355. Protein translocation across the endoplasmic reticulum. I. Detection in the microsomal membrane of a receptor for the signal recognition particle. J Cell Biol. 1982 Nov; 95(2 Pt 1):463-9. Gilmore R, Blobel G, Walter P. PMID: 6292235; PMCID: PMC2112970.
      View in: PubMed   Mentions: 138     Fields:    Translation:Cells
    356. Protein translocation across the endoplasmic reticulum. II. Isolation and characterization of the signal recognition particle receptor. J Cell Biol. 1982 Nov; 95(2 Pt 1):470-7. Gilmore R, Walter P, Blobel G. PMID: 6292236; PMCID: PMC2112977.
      View in: PubMed   Mentions: 184     Fields:    Translation:Cells
    357. A bacterial secretory protein requires signal recognition particle for translocation across mammalian endoplasmic reticulum. J Biol Chem. 1982 Oct 25; 257(20):11860-3. Müller M, Ibrahimi I, Chang CN, Walter P, Blobel G. PMID: 6749848.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    358. Signal recognition particle contains a 7S RNA essential for protein translocation across the endoplasmic reticulum. Nature. 1982 Oct 21; 299(5885):691-8. Walter P, Blobel G. PMID: 6181418.
      View in: PubMed   Mentions: 264     Fields:    Translation:AnimalsCells
    359. Signal recognition protein is required for the integration of acetylcholine receptor delta subunit, a transmembrane glycoprotein, into the endoplasmic reticulum membrane. J Cell Biol. 1982 May; 93(2):501-6. Anderson DJ, Walter P, Blobel G. PMID: 7047541; PMCID: PMC2112847.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    360. Mechanism of protein translocation across the endoplasmic reticulum. Biochem Soc Symp. 1982; 47:183-91. Walter P, Blobel G. PMID: 6100822.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    361. THE PROTEIN TRANSLOCATION MACHINERY OF THE ENDOPLASMIC RETICULUM. Interaction of Translational and Transcriptional Controls in the Regulation of Gene Expression. 1982 Jan 1; 291-293. WALTER WP, GILMORE GR, MULLER MM, BLOBEL BG. .
      View in: Publisher Site   Mentions:
    362. Translocation of proteins across the endoplasmic reticulum. Oncodev Biol Med. 1982; 4(1-2):137-46. Walter P, Blobel G. PMID: 7177879.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    363. Translocation of proteins across the endoplasmic reticulum. I. Signal recognition protein (SRP) binds to in-vitro-assembled polysomes synthesizing secretory protein. J Cell Biol. 1981 Nov; 91(2 Pt 1):545-50. Walter P, Ibrahimi I, Blobel G. PMID: 7309795; PMCID: PMC2111968.
      View in: PubMed   Mentions: 233     Fields:    Translation:AnimalsCells
    364. Translocation of proteins across the endoplasmic reticulum. II. Signal recognition protein (SRP) mediates the selective binding to microsomal membranes of in-vitro-assembled polysomes synthesizing secretory protein. J Cell Biol. 1981 Nov; 91(2 Pt 1):551-6. Walter P, Blobel G. PMID: 7309796; PMCID: PMC2111991.
      View in: PubMed   Mentions: 130     Fields:    Translation:AnimalsCells
    365. Translocation of proteins across the endoplasmic reticulum III. Signal recognition protein (SRP) causes signal sequence-dependent and site-specific arrest of chain elongation that is released by microsomal membranes. J Cell Biol. 1981 Nov; 91(2 Pt 1):557-61. Walter P, Blobel G. PMID: 7309797; PMCID: PMC2111983.
      View in: PubMed   Mentions: 280     Fields:    Translation:AnimalsCells
    366. Purification of a membrane-associated protein complex required for protein translocation across the endoplasmic reticulum. Proc Natl Acad Sci U S A. 1980 Dec; 77(12):7112-6. Walter P, Blobel G. PMID: 6938958; PMCID: PMC350451.
      View in: PubMed   Mentions: 195     Fields:    Translation:AnimalsCells
    367. Secretion requires a cytoplasmically disposed sulphydryl of the RER membrane. Nature. 1980 Jul 10; 286(5769):174-6. Jackson RC, Walter P, Blobel G. PMID: 6995850.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    368. Translocation of proteins across membranes: the signal hypothesis and beyond. Symp Soc Exp Biol. 1979; 33:9-36. Blobel G, Walter P, Chang CN, Goldman BM, Erickson AH, Lingappa VR. PMID: 524275.
      View in: PubMed   Mentions: 76     Fields:    Translation:AnimalsCells
    With one click, see people who:

    Mentor Faculty

    Run Clinical Trials

    Work in Global Health Equity

    Offer Student Projects

    See more options in the Advanced Search tab

    Peter's Networks
    Concepts (849)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (74)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    UCSF Profiles is managed by the UCSF Clinical and Translational Science Institute (CTSI), part of the Clinical and Translational Science Award program funded by the National Center for Advancing Translational Sciences (Grant Number UL1 TR000004) at the National Institutes of Health (NIH).

    We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use. This site is running Profiles RNS version UCSF-v3.1.0-3-g1ef1264b on PROFILES-PWEB04.

    Copyright © The Regents of the University of California.