Phillip Sharp, PhD

TitlePostdoctoral Scholar
SchoolUCSF School of Medicine
DepartmentCellular Molecular Pharmacology
Address600 16th Street
San Francisco CA 94158
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    1. Wang S, Corcilius L, Sharp PP, Payne RJ. Synthesis of a GlcNAcylated arginine building block for the solid phase synthesis of death domain glycopeptide fragments. Bioorg Med Chem. 2017 Jun 01; 25(11):2895-2900. PMID: 28320614.
      View in: PubMed
    2. Wang S, Corcilius L, Sharp PP, Rajkovic A, Ibba M, Parker BL, Payne RJ. Synthesis of rhamnosylated arginine glycopeptides and determination of the glycosidic linkage in bacterial elongation factor P. Chem Sci. 2017 Mar 01; 8(3):2296-2302. PMID: 28451332.
      View in: PubMed
    3. Delconte RB, Kolesnik TB, Dagley LF, Rautela J, Shi W, Putz EM, Stannard K, Zhang JG, Teh C, Firth M, Ushiki T, Andoniou CE, Degli-Esposti MA, Sharp PP, Sanvitale CE, Infusini G, Liau NP, Linossi EM, Burns CJ, Carotta S, Gray DH, Seillet C, Hutchinson DS, Belz GT, Webb AI, Alexander WS, Li SS, Bullock AN, Babon JJ, Smyth MJ, Nicholson SE, Huntington ND. CIS is a potent checkpoint in NK cell-mediated tumor immunity. Nat Immunol. 2016 Jul; 17(7):816-24. PMID: 27213690.
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    4. Baker EK, Taylor S, Gupte A, Sharp PP, Walia M, Walsh NC, Zannettino AC, Chalk AM, Burns CJ, Walkley CR. BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells. Sci Rep. 2015 May 06; 5:10120. PMID: 25944566; PMCID: PMC4421868.
    5. Nachbur U, Stafford CA, Bankovacki A, Zhan Y, Lindqvist LM, Fiil BK, Khakham Y, Ko HJ, Sandow JJ, Falk H, Holien JK, Chau D, Hildebrand J, Vince JE, Sharp PP, Webb AI, Jackman KA, Mühlen S, Kennedy CL, Lowes KN, Murphy JM, Gyrd-Hansen M, Parker MW, Hartland EL, Lew AM, Huang DC, Lessene G, Silke J. A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production. Nat Commun. 2015 Mar 17; 6:6442. PMID: 25778803.
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    6. Hawkins BC, Lindqvist LM, Nhu D, Sharp PP, Segal D, Powell AK, Campbell M, Ryan E, Chambers JM, White JM, Rizzacasa MA, Lessene G, Huang DC, Burns CJ. Simplified silvestrol analogues with potent cytotoxic activity. ChemMedChem. 2014 Jul; 9(7):1556-66. PMID: 24677741.
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    7. Garnier JM, Sharp PP, Burns CJ. BET bromodomain inhibitors: a patent review. Expert Opin Ther Pat. 2014 Feb; 24(2):185-99. PMID: 24261714.
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    8. Sharp PP, Banwell MG, Renner J, Lohmann K, Willis AC. Consecutive gold(I)-catalyzed cyclization reactions of o-(buta-1,3-diyn-1-yl-)-substituted N-aryl ureas: a one-pot synthesis of pyrimido[1,6-a]indol-1(2H)-ones and related systems. Org Lett. 2013 Jun 07; 15(11):2616-9. PMID: 23692341.
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