Robert Blelloch, MD, PhD

Title(s)Professor, Urology
SchoolSchool of Medicine
Address35 Medical Center way, #1018
San Fancisco CA 94143
Phone415-476-2838
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    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Mechanisms of Exosome Driven Immunoregulation of Cancer Progression
    NIH U01CA244452Sep 23, 2019 - Aug 31, 2024
    Role: Principal Investigator
    Rewiring of the pluripotency enhancer network during early mammalian development
    NIH R01GM122439Sep 7, 2017 - Jul 31, 2021
    Role: Principal Investigator
    Iteratively redefining developmental potential through poised enhancers
    NIH R01GM125089Sep 7, 2017 - Jul 31, 2021
    Role: Principal Investigator
    Emergence of divergent cell cycle programs during mammalian development
    NIH R21HD093084Aug 15, 2017 - Jul 31, 2020
    Role: Principal Investigator
    In Vivo Regulated Release and Function of Extracellular Small RNAs
    NIH U19CA179512Sep 1, 2013 - Aug 31, 2019
    Role: Principal Investigator
    MicroRNA Based Pathway Discovery in Cellular Reprogramming
    NIH R01GM101180May 1, 2012 - Apr 30, 2017
    Role: Principal Investigator
    MiRNAs as prognostic markers for prostate cancer patients on active surveillance
    NIH R21CA161615Sep 1, 2011 - Aug 31, 2015
    Role: Principal Investigator
    Small RNAs in Stem Cell Differentiation and Neural Development
    NIH R01NS057221Jun 15, 2007 - May 31, 2014
    Role: Principal Investigator
    Origins and Biological Consequences of Human Infertility
    NIH U54HD055764May 3, 2007 - Mar 31, 2017
    Role: Co-Investigator
    Center for Research, Innovation and Training in Reproduction and Infertility
    NIH P50HD055764Apr 1, 2007 - Mar 31, 2023
    Role: Co-Investigator
    Determinants of Neural &Embryonic Stem Cell Potency
    NIH K08NS048118Jul 1, 2005 - Feb 29, 2012
    Role: Principal Investigator
    Predoctoral Training in Developmental Biology
    NIH T32HD007470Jul 1, 1994 - Apr 30, 2024
    Role: Principal Investigator
    California National Primate Research Center
    NIH P51RR000169Jun 1, 1975 - Apr 30, 2015
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. PVRL2 Suppresses Antitumor Immunity through PVRIG- and TIGIT-independent Pathways. Cancer Immunol Res. 2024 Apr 01; OF1-OF17. Yang J, Wang L, Byrnes JR, Kirkemo LL, Driks H, Belair CD, Aguilar OA, Lanier LL, Wells JA, Fong L, Blelloch R. PMID: 38588410.
      View in: PubMed   Mentions:
    2. MLL3/MLL4 enzymatic activity shapes DNA replication timing. bioRxiv. 2023 Dec 08. Gökbuget D, Boileau RM, Lenshoek K, Blelloch R. PMID: 38106216; PMCID: PMC10723431.
      View in: PubMed   Mentions:
    3. Transcriptional repression upon S phase entry protects genome integrity in pluripotent cells. Nat Struct Mol Biol. 2023 10; 30(10):1561-1570. Gökbuget D, Lenshoek K, Boileau RM, Bayerl J, Huang H, Wiita AP, Laird DJ, Blelloch R. PMID: 37696959.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    4. Loss of MLL3/4 decouples enhancer H3K4 monomethylation, H3K27 acetylation, and gene activation during embryonic stem cell differentiation. Genome Biol. 2023 03 03; 24(1):41. Boileau RM, Chen KX, Blelloch R. PMID: 36869380; PMCID: PMC9983171.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    5. Regionally distinct trophoblast regulate barrier function and invasion in the human placenta. Elife. 2022 07 07; 11. Marsh B, Zhou Y, Kapidzic M, Fisher S, Blelloch R. PMID: 35796428; PMCID: PMC9323019.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    6. G1/S restriction point coordinates phasic gene expression and cell differentiation. Nat Commun. 2022 06 27; 13(1):3696. DeVeale B, Liu L, Boileau R, Swindlehurst-Chan J, Marsh B, Freimer JW, Abate A, Blelloch R. PMID: 35760790; PMCID: PMC9237072.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    7. Beyond Maternal Tolerance: Education of Uterine Natural Killer Cells by Maternal MHC Drives Fetal Growth. Front Immunol. 2022; 13:808227. Depierreux DM, Kieckbusch J, Shreeve N, Hawkes DA, Marsh B, Blelloch R, Sharkey A, Colucci F. PMID: 35619712; PMCID: PMC9127083.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    8. Cell-surface tethered promiscuous biotinylators enable comparative small-scale surface proteomic analysis of human extracellular vesicles and cells. Elife. 2022 03 08; 11. Kirkemo LL, Elledge SK, Yang J, Byrnes JR, Glasgow JE, Blelloch R, Wells JA. PMID: 35257663; PMCID: PMC8983049.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    9. The roles of microRNAs in mouse development. Nat Rev Genet. 2021 05; 22(5):307-323. DeVeale B, Swindlehurst-Chan J, Blelloch R. PMID: 33452500.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    10. Single nuclei RNA-seq of mouse placental labyrinth development. Elife. 2020 11 03; 9. Marsh B, Blelloch R. PMID: 33141023; PMCID: PMC7669270.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    11. MicroRNA-dependent inhibition of PFN2 orchestrates ERK activation and pluripotent state transitions by regulating endocytosis. Proc Natl Acad Sci U S A. 2020 08 25; 117(34):20625-20635. Sangokoya C, Blelloch R. PMID: 32788350; PMCID: PMC7456128.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    12. LIN28B Impairs the Transition of hESC-Derived β Cells from the Juvenile to Adult State. Stem Cell Reports. 2020 01 14; 14(1):9-20. Zhou X, Nair GG, Russ HA, Belair CD, Li ML, Shveygert M, Hebrok M, Blelloch R. PMID: 31883920; PMCID: PMC6962644.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    13. Epigenetic control of transcriptional regulation in pluripotency and early differentiation. Development. 2019 09 25; 146(19). Gökbuget D, Blelloch R. PMID: 31554624; PMCID: PMC6803368.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    14. Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory. Cell. 2019 04 04; 177(2):414-427.e13. Poggio M, Hu T, Pai CC, Chu B, Belair CD, Chang A, Montabana E, Lang UE, Fu Q, Fong L, Blelloch R. PMID: 30951669; PMCID: PMC6499401.
      View in: PubMed   Mentions: 531     Fields:    Translation:HumansAnimalsCells
    15. High-throughput, Efficient, and Unbiased Capture of Small RNAs from Low-input Samples for Sequencing. Sci Rep. 2019 02 19; 9(1):2262. Belair CD, Hu T, Chu B, Freimer JW, Cooperberg MR, Blelloch RH. PMID: 30783180; PMCID: PMC6381177.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    16. FOXD3 Regulates Pluripotent Stem Cell Potential by Simultaneously Initiating and Repressing Enhancer Activity. Cell Stem Cell. 2018 Aug 02; 23(2):306-307. Krishnakumar R, Chen AF, Pantovich MG, Danial M, Parchem RJ, Labosky PA, Blelloch R. PMID: 30075131.
      View in: PubMed   Mentions: 3     Fields:    
    17. Decoupling the impact of microRNAs on translational repression versus RNA degradation in embryonic stem cells. Elife. 2018 07 25; 7. Freimer JW, Hu TJ, Blelloch R. PMID: 30044225; PMCID: PMC6086665.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    18. GRHL2-Dependent Enhancer Switching Maintains a Pluripotent Stem Cell Transcriptional Subnetwork after Exit from Naive Pluripotency. Cell Stem Cell. 2018 Aug 02; 23(2):226-238.e4. Chen AF, Liu AJ, Krishnakumar R, Freimer JW, DeVeale B, Blelloch R. PMID: 30017589; PMCID: PMC6456389.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    19. Expression of Alternative Ago2 Isoform Associated with Loss of microRNA-Driven Translational Repression in Mouse Oocytes. Curr Biol. 2018 01 22; 28(2):296-302.e3. Freimer JW, Krishnakumar R, Cook MS, Blelloch R. PMID: 29307557; PMCID: PMC5790201.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    20. The eutheria-specific miR-290 cluster modulates placental growth and maternal-fetal transport. Development. 2017 10 15; 144(20):3731-3743. Paikari A, D Belair C, Saw D, Blelloch R. PMID: 28935707; PMCID: PMC5675445.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    21. NF45 and NF90/NF110 coordinately regulate ESC pluripotency and differentiation. RNA. 2017 08; 23(8):1270-1284. Ye J, Jin H, Pankov A, Song JS, Blelloch R. PMID: 28487382; PMCID: PMC5513071.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    22. Patterning of sharp cellular interfaces with a reconfigurable elastic substrate. Integr Biol (Camb). 2017 01 23; 9(1):50-57. Curtis A, Li DJ, DeVeale B, Onishi K, Kim MY, Blelloch R, Laird DJ, Hui EE. PMID: 28001149; PMCID: PMC5575999.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    23. The impact of microRNAs on transcriptional heterogeneity and gene co-expression across single embryonic stem cells. Nat Commun. 2017 01 19; 8:14126. Gambardella G, Carissimo A, Chen A, Cutillo L, Nowakowski TJ, di Bernardo D, Blelloch R. PMID: 28102192; PMCID: PMC5253645.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    24. Vitamin C and l-Proline Antagonistic Effects Capture Alternative States in the Pluripotency Continuum. Stem Cell Reports. 2017 01 10; 8(1):1-10. D'Aniello C, Habibi E, Cermola F, Paris D, Russo F, Fiorenzano A, Di Napoli G, Melck DJ, Cobellis G, Angelini C, Fico A, Blelloch R, Motta A, Stunnenberg HG, De Cesare D, Patriarca EJ, Minchiotti G. PMID: 28017658; PMCID: PMC5233408.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    25. miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation. Cell Rep. 2016 11 22; 17(9):2271-2285. Coffre M, Benhamou D, Rieß D, Blumenberg L, Snetkova V, Hines MJ, Chakraborty T, Bajwa S, Jensen K, Chong MMW, Getu L, Silverman GJ, Blelloch R, Littman DR, Calado D, Melamed D, Skok JA, Rajewsky K, Koralov SB. PMID: 27880903; PMCID: PMC5679080.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    26. A miR-372/let-7 Axis Regulates Human Germ Versus Somatic Cell Fates. Stem Cells. 2016 07; 34(7):1985-91. Tran ND, Kissner M, Subramanyam D, Parchem RJ, Laird DJ, Blelloch RH. PMID: 27066911; PMCID: PMC5145290.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    27. FOXD3 Regulates Pluripotent Stem Cell Potential by Simultaneously Initiating and Repressing Enhancer Activity. Cell Stem Cell. 2016 Jan 07; 18(1):104-17. Krishnakumar R, Chen AF, Pantovich MG, Danial M, Parchem RJ, Labosky PA, Blelloch R. PMID: 26748757; PMCID: PMC4775235.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    28. Fas-Activated Mitochondrial Apoptosis Culls Stalled Embryonic Stem Cells to Promote Differentiation. Curr Biol. 2015 Dec 07; 25(23):3110-8. Wang ES, Reyes NA, Melton C, Huskey NE, Momcilovic O, Goga A, Blelloch R, Oakes SA. PMID: 26585277; PMCID: PMC4703423.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    29. Biogenesis, delivery, and function of extracellular RNA. J Extracell Vesicles. 2015; 4:27494. Patton JG, Franklin JL, Weaver AM, Vickers K, Zhang B, Coffey RJ, Ansel KM, Blelloch R, Goga A, Huang B, L'Etoille N, Raffai RL, Lai CP, Krichevsky AM, Mateescu B, Greiner VJ, Hunter C, Voinnet O, McManus MT. PMID: 26320939; PMCID: PMC4553266.
      View in: PubMed   Mentions: 46     Fields:    
    30. miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability. Cell Rep. 2015 Aug 04; 12(5):760-73. Parchem RJ, Moore N, Fish JL, Parchem JG, Braga TT, Shenoy A, Oldham MC, Rubenstein JL, Schneider RA, Blelloch R. PMID: 26212322; PMCID: PMC4741278.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    31. DGCR8 is essential for tumor progression following PTEN loss in the prostate. EMBO Rep. 2015 Sep; 16(9):1219-32. Belair CD, Paikari A, Moltzahn F, Shenoy A, Yau C, Dall'Era M, Simko J, Benz C, Blelloch R. PMID: 26206718; PMCID: PMC4576988.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    32. Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro. EMBO J. 2015 Jul 02; 34(13):1759-72. Russ HA, Parent AV, Ringler JJ, Hennings TG, Nair GG, Shveygert M, Guo T, Puri S, Haataja L, Cirulli V, Blelloch R, Szot GL, Arvan P, Hebrok M. PMID: 25908839; PMCID: PMC4516429.
      View in: PubMed   Mentions: 294     Fields:    Translation:HumansAnimalsCells
    33. CDK1 inhibition targets the p53-NOXA-MCL1 axis, selectively kills embryonic stem cells, and prevents teratoma formation. Stem Cell Reports. 2015 Mar 10; 4(3):374-89. Huskey NE, Guo T, Evason KJ, Momcilovic O, Pardo D, Creasman KJ, Judson RL, Blelloch R, Oakes SA, Hebrok M, Goga A. PMID: 25733019; PMCID: PMC4375943.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    34. Let-7 and miR-125 cooperate to prime progenitors for astrogliogenesis. EMBO J. 2015 May 05; 34(9):1180-94. Shenoy A, Danial M, Blelloch RH. PMID: 25715649; PMCID: PMC4426479.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    35. Early postnatal ablation of the microRNA-processing enzyme, Drosha, causes chondrocyte death and impairs the structural integrity of the articular cartilage. Osteoarthritis Cartilage. 2015 Jul; 23(7):1214-20. Kobayashi T, Papaioannou G, Mirzamohammadi F, Kozhemyakina E, Zhang M, Blelloch R, Chong MW. PMID: 25707934; PMCID: PMC4470813.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    36. Suppression of epithelial-mesenchymal transition and apoptotic pathways by miR-294/302 family synergistically blocks let-7-induced silencing of self-renewal in embryonic stem cells. Cell Death Differ. 2015 Jul; 22(7):1158-69. Guo WT, Wang XW, Yan YL, Li YP, Yin X, Zhang Q, Melton C, Shenoy A, Reyes NA, Oakes SA, Blelloch R, Wang Y. PMID: 25501598; PMCID: PMC4572863.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    37. Regulation of pluripotency by RNA binding proteins. Cell Stem Cell. 2014 Sep 04; 15(3):271-280. Ye J, Blelloch R. PMID: 25192462; PMCID: PMC4372238.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    38. Regulation of microRNA function in somatic stem cell proliferation and differentiation. Nat Rev Mol Cell Biol. 2014 Sep; 15(9):565-76. Shenoy A, Blelloch RH. PMID: 25118717; PMCID: PMC4377327.
      View in: PubMed   Mentions: 169     Fields:    Translation:HumansAnimalsCells
    39. miR-19, miR-345, miR-519c-5p serum levels predict adverse pathology in prostate cancer patients eligible for active surveillance. PLoS One. 2014; 9(6):e98597. Wang SY, Shiboski S, Belair CD, Cooperberg MR, Simko JP, Stoppler H, Cowan J, Carroll PR, Blelloch R. PMID: 24893170; PMCID: PMC4043973.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    40. Two miRNA clusters reveal alternative paths in late-stage reprogramming. Cell Stem Cell. 2014 May 01; 14(5):617-31. Parchem RJ, Ye J, Judson RL, LaRussa MF, Krishnakumar R, Blelloch A, Oldham MC, Blelloch R. PMID: 24630794; PMCID: PMC4305531.
      View in: PubMed   Mentions: 53     Fields:    Translation:Animals
    41. MicroRNA-based discovery of barriers to dedifferentiation of fibroblasts to pluripotent stem cells. Nat Struct Mol Biol. 2013 Oct; 20(10):1227-35. Judson RL, Greve TS, Parchem RJ, Blelloch R. PMID: 24037508; PMCID: PMC3955211.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    42. Epigenetics of cellular reprogramming. Curr Opin Genet Dev. 2013 Oct; 23(5):548-55. Krishnakumar R, Blelloch RH. PMID: 23948105; PMCID: PMC4359361.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    43. microRNA control of mouse and human pluripotent stem cell behavior. Annu Rev Cell Dev Biol. 2013; 29:213-239. Greve TS, Judson RL, Blelloch R. PMID: 23875649; PMCID: PMC4793955.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    44. miR-294/miR-302 promotes proliferation, suppresses G1-S restriction point, and inhibits ESC differentiation through separable mechanisms. Cell Rep. 2013 Jul 11; 4(1):99-109. Wang Y, Melton C, Li YP, Shenoy A, Zhang XX, Subramanyam D, Blelloch R. PMID: 23831024; PMCID: PMC3740202.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    45. DGCR8-mediated production of canonical microRNAs is critical for regulatory T cell function and stability. PLoS One. 2013; 8(5):e66282. Jeker LT, Zhou X, Blelloch R, Bluestone JA. PMID: 23741528; PMCID: PMC3669207.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    46. Epigenetics, noncoding RNAs, and cell signaling--crossroads in the regulation of cell fate decisions. Curr Opin Cell Biol. 2013 Apr; 25(2):149-51. Blelloch R, Gutkind JS. PMID: 23498659.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    47. Regulation of epithelial-mesenchymal and mesenchymal-epithelial transitions by microRNAs. Curr Opin Cell Biol. 2013 Apr; 25(2):200-7. Lamouille S, Subramanyam D, Blelloch R, Derynck R. PMID: 23434068; PMCID: PMC4240277.
      View in: PubMed   Mentions: 137     Fields:    Translation:HumansAnimalsCells
    48. Small RNAs in germline development. Curr Top Dev Biol. 2013; 102:159-205. Cook MS, Blelloch R. PMID: 23287033.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    49. An integrated nano-scale approach to profile miRNAs in limited clinical samples. Am J Clin Exp Immunol. 2012 Nov 30; 1(2):70-89. Seumois G, Vijayanand P, Eisley CJ, Omran N, Kalinke L, North M, Ganesan AP, Simpson LJ, Hunkapiller N, Moltzahn F, Woodruff PG, Fahy JV, Erle DJ, Djukanovic R, Blelloch R, Ansel KM. PMID: 23304658; PMCID: PMC3538381.
      View in: PubMed   Mentions: 24  
    50. Sox1 marks an activated neural stem/progenitor cell in the hippocampus. Development. 2012 Nov; 139(21):3938-49. Venere M, Han YG, Bell R, Song JS, Alvarez-Buylla A, Blelloch R. PMID: 22992951; PMCID: PMC3472585.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    51. Loss of microRNAs in pyramidal neurons leads to specific changes in inhibitory synaptic transmission in the prefrontal cortex. Mol Cell Neurosci. 2012 Jul; 50(3-4):283-92. Hsu R, Schofield CM, Dela Cruz CG, Jones-Davis DM, Blelloch R, Ullian EM. PMID: 22728723; PMCID: PMC3613865.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    52. Generation of induced pluripotent stem cells from the prairie vole. PLoS One. 2012; 7(5):e38119. Manoli DS, Subramanyam D, Carey C, Sudin E, Van Westerhuyzen JA, Bales KL, Blelloch R, Shah NM. PMID: 22675440; PMCID: PMC3365000.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    53. Efficiency and specificity in microRNA biogenesis. Nat Struct Mol Biol. 2012 May 13; 19(6):650-2. Barad O, Mann M, Chapnik E, Shenoy A, Blelloch R, Barkai N, Hornstein E. PMID: 22580560; PMCID: PMC4378260.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    54. microRNA induced transdifferentiation. F1000 Biol Rep. 2012; 4:3. Shenoy A, Blelloch R. PMID: 22312415; PMCID: PMC3270586.
      View in: PubMed   Mentions: 12  
    55. Dgcr8 controls neural crest cells survival in cardiovascular development. Dev Biol. 2012 Feb 01; 362(1):50-6. Chapnik E, Sasson V, Blelloch R, Hornstein E. PMID: 22138056.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    56. MicroRNA-29 regulates T-box transcription factors and interferon-γ production in helper T cells. Immunity. 2011 Aug 26; 35(2):169-81. Steiner DF, Thomas MF, Hu JK, Yang Z, Babiarz JE, Allen CD, Matloubian M, Blelloch R, Ansel KM. PMID: 21820330; PMCID: PMC3361370.
      View in: PubMed   Mentions: 194     Fields:    Translation:AnimalsCells
    57. High throughput microRNA profiling: optimized multiplex qRT-PCR at nanoliter scale on the fluidigm dynamic arrayTM IFCs. J Vis Exp. 2011 Aug 03; (54). Moltzahn F, Hunkapiller N, Mir AA, Imbar T, Blelloch R. PMID: 21847076; PMCID: PMC3211115.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    58. A role for noncanonical microRNAs in the mammalian brain revealed by phenotypic differences in Dgcr8 versus Dicer1 knockouts and small RNA sequencing. RNA. 2011 Aug; 17(8):1489-501. Babiarz JE, Hsu R, Melton C, Thomas M, Ullian EM, Blelloch R. PMID: 21712401; PMCID: PMC3153973.
      View in: PubMed   Mentions: 75     Fields:    Translation:Animals
    59. From microRNAs to targets: pathway discovery in cell fate transitions. Curr Opin Genet Dev. 2011 Aug; 21(4):498-503. Subramanyam D, Blelloch R. PMID: 21636265; PMCID: PMC3210035.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    60. Small RNAs in early mammalian development: from gametes to gastrulation. Development. 2011 May; 138(9):1653-61. Suh N, Blelloch R. PMID: 21486922; PMCID: PMC3074443.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    61. Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells. Nat Biotechnol. 2011 May; 29(5):443-8. Subramanyam D, Lamouille S, Judson RL, Liu JY, Bucay N, Derynck R, Blelloch R. PMID: 21490602; PMCID: PMC3685579.
      View in: PubMed   Mentions: 300     Fields:    Translation:HumansCells
    62. Monoallelic deletion of the microRNA biogenesis gene Dgcr8 produces deficits in the development of excitatory synaptic transmission in the prefrontal cortex. Neural Dev. 2011 Apr 05; 6:11. Schofield CM, Hsu R, Barker AJ, Gertz CC, Blelloch R, Ullian EM. PMID: 21466685; PMCID: PMC3082233.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    63. Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition. Genes Dev. 2011 Apr 01; 25(7):755-66. Chen J, Melton C, Suh N, Oh JS, Horner K, Xie F, Sette C, Blelloch R, Conti M. PMID: 21460039; PMCID: PMC3070937.
      View in: PubMed   Mentions: 125     Fields:    Translation:AnimalsCells
    64. Cell cycle regulation by microRNAs in stem cells. Results Probl Cell Differ. 2011; 53:459-72. Wang Y, Blelloch R. PMID: 21630156.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    65. Microfluidic-based multiplex qRT-PCR identifies diagnostic and prognostic microRNA signatures in the sera of prostate cancer patients. Cancer Res. 2011 Jan 15; 71(2):550-60. Moltzahn F, Olshen AB, Baehner L, Peek A, Fong L, Stöppler H, Simko J, Hilton JF, Carroll P, Blelloch R. PMID: 21098088; PMCID: PMC3022112.
      View in: PubMed   Mentions: 142     Fields:    Translation:Humans
    66. On the streets of San Francisco: highlights from the ISSCR Annual Meeting 2010. Cell Stem Cell. 2010 Oct 08; 7(4):443-50. Elefanty AG, Blelloch R, Passegué E, Wernig M, Mummery CL. PMID: 20887950.
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    67. miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma. Nat Med. 2010 Oct; 16(10):1134-40. Swarbrick A, Woods SL, Shaw A, Balakrishnan A, Phua Y, Nguyen A, Chanthery Y, Lim L, Ashton LJ, Judson RL, Huskey N, Blelloch R, Haber M, Norris MD, Lengyel P, Hackett CS, Preiss T, Chetcuti A, Sullivan CS, Marcusson EG, Weiss W, L'Etoile N, Goga A. PMID: 20871609; PMCID: PMC3019350.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    68. PML-RAR{alpha} and Dnmt3a1 cooperate in vivo to promote acute promyelocytic leukemia. Cancer Res. 2010 Nov 01; 70(21):8792-801. Subramanyam D, Belair CD, Barry-Holson KQ, Lin H, Kogan SC, Passegué E, Blelloch R. PMID: 20861188; PMCID: PMC3021794.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    69. Distinct requirements of microRNAs in NK cell activation, survival, and function. J Immunol. 2010 Oct 01; 185(7):3835-46. Bezman NA, Cedars E, Steiner DF, Blelloch R, Hesslein DG, Lanier LL. PMID: 20805417; PMCID: PMC2943981.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    70. MicroRNAs control hepatocyte proliferation during liver regeneration. Hepatology. 2010 May; 51(5):1735-43. Song G, Sharma AD, Roll GR, Ng R, Lee AY, Blelloch RH, Frandsen NM, Willenbring H. PMID: 20432256; PMCID: PMC3108060.
      View in: PubMed   Mentions: 98     Fields:    Translation:AnimalsCells
    71. Mammalian microRNAs: experimental evaluation of novel and previously annotated genes. Genes Dev. 2010 May 15; 24(10):992-1009. Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP. PMID: 20413612; PMCID: PMC2867214.
      View in: PubMed   Mentions: 457     Fields:    Translation:HumansAnimalsCells
    72. MicroRNA function is globally suppressed in mouse oocytes and early embryos. Curr Biol. 2010 Feb 09; 20(3):271-7. Suh N, Baehner L, Moltzahn F, Melton C, Shenoy A, Chen J, Blelloch R. PMID: 20116247; PMCID: PMC2872512.
      View in: PubMed   Mentions: 192     Fields:    Translation:AnimalsCells
    73. Opposing microRNA families regulate self-renewal in mouse embryonic stem cells. Nature. 2010 Feb 04; 463(7281):621-6. Melton C, Judson RL, Blelloch R. PMID: 20054295; PMCID: PMC2894702.
      View in: PubMed   Mentions: 372     Fields:    Translation:AnimalsCells
    74. MicroRNA Regulation of Embryonic Stem Cell Self-Renewal and Differentiation. Adv Exp Med Biol. 2010; 695:105-17. Melton C, Blelloch R. PMID: 21222202.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    75. Journal club. A computational biologist looks at how mRNA length changes during development. Nature. 2009 Nov 12; 462(7270):141. Blelloch R. PMID: 19907454.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    76. Watching reprogramming in real time. Nat Biotechnol. 2009 Nov; 27(11):997-8. Subramanyam D, Blelloch R. PMID: 19898451.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    77. Genomic analysis suggests that mRNA destabilization by the microprocessor is specialized for the auto-regulation of Dgcr8. PLoS One. 2009 Sep 11; 4(9):e6971. Shenoy A, Blelloch R. PMID: 19759829; PMCID: PMC2736397.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    78. Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failure. Circ Res. 2009 Sep 11; 105(6):585-94. Rao PK, Toyama Y, Chiang HR, Gupta S, Bauer M, Medvid R, Reinhardt F, Liao R, Krieger M, Jaenisch R, Lodish HF, Blelloch R. PMID: 19679836; PMCID: PMC2828903.
      View in: PubMed   Mentions: 177     Fields:    Translation:AnimalsCells
    79. Cell cycle regulation by MicroRNAs in embryonic stem cells. Cancer Res. 2009 May 15; 69(10):4093-6. Wang Y, Blelloch R. PMID: 19435891; PMCID: PMC2894693.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansCells
    80. Embryonic stem cell-specific microRNAs promote induced pluripotency. Nat Biotechnol. 2009 May; 27(5):459-61. Judson RL, Babiarz JE, Venere M, Blelloch R. PMID: 19363475; PMCID: PMC2743930.
      View in: PubMed   Mentions: 332     Fields:    Translation:AnimalsCells
    81. Posttranscriptional crossregulation between Drosha and DGCR8. Cell. 2009 Jan 09; 136(1):75-84. Han J, Pedersen JS, Kwon SC, Belair CD, Kim YK, Yeom KH, Yang WY, Haussler D, Blelloch R, Kim VN. PMID: 19135890; PMCID: PMC2680683.
      View in: PubMed   Mentions: 233     Fields:    Translation:HumansAnimalsCells
    82. Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation. Nat Genet. 2008 Dec; 40(12):1478-83. Wang Y, Baskerville S, Shenoy A, Babiarz JE, Baehner L, Blelloch R. PMID: 18978791; PMCID: PMC2630798.
      View in: PubMed   Mentions: 335     Fields:    Translation:AnimalsCells
    83. CompMoby: comparative MobyDick for detection of cis-regulatory motifs. BMC Bioinformatics. 2008 Oct 27; 9:455. Chaivorapol C, Melton C, Wei G, Yeh RF, Ramalho-Santos M, Blelloch R, Li H. PMID: 18950538; PMCID: PMC2605473.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    84. Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs. Genes Dev. 2008 Oct 15; 22(20):2773-85. Babiarz JE, Ruby JG, Wang Y, Bartel DP, Blelloch R. PMID: 18923076; PMCID: PMC2569885.
      View in: PubMed   Mentions: 479     Fields:    Translation:AnimalsCells
    85. Regenerative medicine: short cut to cell replacement. Nature. 2008 Oct 02; 455(7213):604-5. Blelloch R. PMID: 18833266.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    86. Generation of induced pluripotent stem cells in the absence of drug selection. Cell Stem Cell. 2007 Sep 13; 1(3):245-7. Blelloch R, Venere M, Yen J, Ramalho-Santos M. PMID: 18371358; PMCID: PMC2894698.
      View in: PubMed   Mentions: 103     Fields:    Translation:AnimalsCells
    87. DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat Genet. 2007 Mar; 39(3):380-5. Wang Y, Medvid R, Melton C, Jaenisch R, Blelloch R. PMID: 17259983; PMCID: PMC3008549.
      View in: PubMed   Mentions: 510     Fields:    Translation:AnimalsCells
    88. Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus. Stem Cells. 2006 Sep; 24(9):2007-13. Blelloch R, Wang Z, Meissner A, Pollard S, Smith A, Jaenisch R. PMID: 16709876; PMCID: PMC3000431.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    89. Nuclear cloning of embryonal carcinoma cells. Proc Natl Acad Sci U S A. 2004 Sep 28; 101(39):13985-90. Blelloch RH, Hochedlinger K, Yamada Y, Brennan C, Kim M, Mintz B, Chin L, Jaenisch R. PMID: 15306687; PMCID: PMC521109.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    90. TRA-1/GLI controls development of somatic gonadal precursors in C. elegans. Development. 2004 Sep; 131(17):4333-43. Mathies LD, Schvarzstein M, Morphy KM, Blelloch R, Spence AM, Kimble J. PMID: 15294864.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    91. Reprogramming of a melanoma genome by nuclear transplantation. Genes Dev. 2004 Aug 01; 18(15):1875-85. Hochedlinger K, Blelloch R, Brennan C, Yamada Y, Kim M, Chin L, Jaenisch R. PMID: 15289459; PMCID: PMC517407.
      View in: PubMed   Mentions: 142     Fields:    Translation:AnimalsCells
    92. Nuclear cloning, epigenetic reprogramming, and cellular differentiation. Cold Spring Harb Symp Quant Biol. 2004; 69:19-27. Jaenisch R, Hochedlinger K, Blelloch R, Yamada Y, Baldwin K, Eggan K. PMID: 16117629.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    93. Nuclear transplantation, embryonic stem cells and the potential for cell therapy. Hematol J. 2004; 5 Suppl 3:S114-7. Hochedlinger K, Rideout WM, Kyba M, Daley GQ, Blelloch R, Jaenisch R. PMID: 15190291.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    94. The gon-1 gene is required for gonadal morphogenesis in Caenorhabditis elegans. Dev Biol. 1999 Dec 01; 216(1):382-93. Blelloch R, Anna-Arriola SS, Gao D, Li Y, Hodgkin J, Kimble J. PMID: 10588887.
      View in: PubMed   Mentions: 67     Fields:    Translation:Animals
    95. Control of cell migration during Caenorhabditis elegans development. Curr Opin Cell Biol. 1999 Oct; 11(5):608-13. Blelloch R, Newman C, Kimble J. PMID: 10508660.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    96. Control of organ shape by a secreted metalloprotease in the nematode Caenorhabditis elegans. Nature. 1999 Jun 10; 399(6736):586-90. Blelloch R, Kimble J. PMID: 10376599.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    97. Roles of the RAM and ANK domains in signaling by the C. elegans GLP-1 receptor. EMBO J. 1996 Dec 16; 15(24):7002-12. Roehl H, Bosenberg M, Blelloch R, Kimble J. PMID: 9003776; PMCID: PMC452526.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    98. A molecular genetic model of human bladder cancer pathogenesis. Semin Oncol. 1996 Oct; 23(5):571-84. Reznikoff CA, Belair CD, Yeager TR, Savelieva E, Blelloch RH, Puthenveettil JA, Cuthill S. PMID: 8893868.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
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