Loading...

Ruby Ghadially, MD

TitleProfessor
SchoolUCSF School of Medicine
DepartmentDermatology
AddressVA 203, 4150 Clement St.
San Francisco CA 94121
Phone415-221-4810
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    Characterization of Human Epidermal Stem Cells
    VA I01BX000794Oct 1, 2010 - Sep 30, 2014
    Role: Principal Investigator
    Reversing Epidermal Stem Cell Aging: Role of Bmi-1 and the Stem Cell Niche
    NIH/NIAMS R21AR060651Sep 10, 2010 - May 31, 2013
    Role: Principal Investigator
    Characterization of Epidermal Stem Cells
    NIH/NIAMS R01AR053765Sep 1, 2005 - May 31, 2011
    Role: Principal Investigator
    Epidermal Stem Cells: Age-Related Changes
    NIH/NIAMS R03AR048667Sep 15, 2002 - Aug 31, 2005
    Role: Principal Investigator
    Age-Related Changes in Epidermal Stem Cells
    NIH/NIA R03AG020372Sep 30, 2001 - Aug 31, 2003
    Role: Principal Investigator
    CYTOKINE EXPRESSION AND SIGNALLING IN AGED EPIDERMIS
    NIH/NIAMS K08AR001973Jul 20, 1996 - May 31, 2002
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Charruyer A, Fong S, Vitcov GG, Sklar S, Tabernik L, Taneja M, Caputo M, Soeung C, Yue L, Uchida Y, Arron ST, Horton KM, Foster RD, Sano S, North JP, Ghadially R. Brief Report: Interleukin-17A-Dependent Asymmetric Stem Cell Divisions Are Increased in Human Psoriasis: A Mechanism Underlying Benign Hyperproliferation. Stem Cells. 2017 Aug; 35(8):2001-2007. PMID: 28600817.
      View in: PubMed
    2. Ghadially R, Marcus P. Feroze N. Ghadially - Polymath Extraordinaire. Ultrastruct Pathol. 2017 Jan-Feb; 41(1):68. PMID: 28230513.
      View in: PubMed
    3. Charruyer A, Fong S, Yue L, Arron ST, Ghadially R. Phycosaccharide AI, a mixture of alginate polysaccharides, increases stem cell proliferation in aged keratinocytes. Exp Dermatol. 2016 Sep; 25(9):738-40. PMID: 27095184.
      View in: PubMed
    4. Yue L, Huang ZM, Fong S, Leong S, Jakowatz JG, Charruyer-Reinwald A, Wei M, Ghadially R. Targeting ALDH1 to decrease tumorigenicity, growth and metastasis of human melanoma. Melanoma Res. 2015 Apr; 25(2):138-48. PMID: 25643237.
      View in: PubMed
    5. Szabo AZ, Fong S, Yue L, Zhang K, Strachan LR, Scalapino K, Mancianti ML, Ghadially R. The CD44+ ALDH+ population of human keratinocytes is enriched for epidermal stem cells with long-term repopulating ability. Stem Cells. 2013 Apr; 31(4):786-99. PMID: 23335266; PMCID: PMC4104573.
    6. Charruyer A, Strachan LR, Yue L, Toth AS, Cecchini G, Mancianti ML, Ghadially R. CD133 is a marker for long-term repopulating murine epidermal stem cells. J Invest Dermatol. 2012 Nov; 132(11):2522-33. PMID: 22763787; PMCID: PMC3997791.
    7. Ghadially R. 25 years of epidermal stem cell research. J Invest Dermatol. 2012 Mar; 132(3 Pt 2):797-810. PMID: 22205306; PMCID: PMC3998762.
    8. Ghadially R. The role of stem and circulating cells in cancer metastasis. J Surg Oncol. 2011 May 1; 103(6):555-7. PMID: 21480249.
      View in: PubMed
    9. Charruyer A, Ghadially R. What's new in dermatology: epidermal stem cells. G Ital Dermatol Venereol. 2011 Feb; 146(1):57-67. PMID: 21317858.
      View in: PubMed
    10. Boonyaratanakornkit JB, Yue L, Strachan LR, Scalapino KJ, LeBoit PE, Lu Y, Leong SP, Smith JE, Ghadially R. Selection of tumorigenic melanoma cells using ALDH. J Invest Dermatol. 2010 Dec; 130(12):2799-808. PMID: 20739950.
      View in: PubMed
    11. Strachan LR, Ghadially R. Limiting dilution analysis of murine epidermal stem cells using an in vivo regeneration assay. Methods Mol Biol. 2010; 585:421-32. PMID: 19908020; PMCID: PMC2783164.
    12. Charruyer A, Barland CO, Yue L, Wessendorf HB, Lu Y, Lawrence HJ, Mancianti ML, Ghadially R. Transit-amplifying cell frequency and cell cycle kinetics are altered in aged epidermis. J Invest Dermatol. 2009 Nov; 129(11):2574-83. PMID: 19458632.
      View in: PubMed
    13. Charruyer A, Ghadially R. Stem cells and tissue-engineered skin. Skin Pharmacol Physiol. 2009; 22(2):55-62. PMID: 19188753; PMCID: PMC2709994.
    14. Strachan LR, Ghadially R. Tiers of clonal organization in the epidermis: the epidermal proliferation unit revisited. Stem Cell Rev. 2008 Sep; 4(3):149-57. PMID: 18574734.
      View in: PubMed
    15. Strachan LR, Scalapino KJ, Lawrence HJ, Ghadially R. Rapid adhesion to collagen isolates murine keratinocytes with limited long-term repopulating ability in vivo despite high clonogenicity in vitro. Stem Cells. 2008 Jan; 26(1):235-43. PMID: 17932419.
      View in: PubMed
    16. Silvander M, Ringstad L, Ghadially R, Sk├Âld T. A new water-based topical carrier with polar skin-lipids. Lipids Health Dis. 2006; 5:12. PMID: 16672068; PMCID: PMC1464131.
    17. Ghadially R. Epidermal stem cells. Adv Dermatol. 2005; 21:335-55. PMID: 16350449.
      View in: PubMed
    18. Ghadially R. In search of the elusive epidermal stem cell. Ernst Schering Res Found Workshop. 2005; (54):45-62. PMID: 16080286.
      View in: PubMed
    19. Barland CO, Zettersten E, Brown BS, Ye J, Elias PM, Ghadially R. Imiquimod-induced interleukin-1 alpha stimulation improves barrier homeostasis in aged murine epidermis. J Invest Dermatol. 2004 Feb; 122(2):330-6. PMID: 15009713.
      View in: PubMed
    20. Schneider TE, Barland C, Alex AM, Mancianti ML, Lu Y, Cleaver JE, Lawrence HJ, Ghadially R. Measuring stem cell frequency in epidermis: a quantitative in vivo functional assay for long-term repopulating cells. Proc Natl Acad Sci U S A. 2003 Sep 30; 100(20):11412-7. PMID: 13679571; PMCID: PMC208771.
    21. Ye J, Garg A, Calhoun C, Feingold KR, Elias PM, Ghadially R. Alterations in cytokine regulation in aged epidermis: implications for permeability barrier homeostasis and inflammation. I. IL-1 gene family. Exp Dermatol. 2002 Jun; 11(3):209-16. PMID: 12102659.
      View in: PubMed
    22. Elias PM, Ghadially R. The aged epidermal permeability barrier: basis for functional abnormalities. Clin Geriatr Med. 2002 Feb; 18(1):103-20, vii. PMID: 11913735.
      View in: PubMed
    23. Kao JS, Garg A, Mao-Qiang M, Crumrine D, Ghadially R, Feingold KR, Elias PM. Testosterone perturbs epidermal permeability barrier homeostasis. J Invest Dermatol. 2001 Mar; 116(3):443-51. PMID: 11231319.
      View in: PubMed
    24. Zettersten E, Man MQ, Sato J, Denda M, Farrell A, Ghadially R, Williams ML, Feingold KR, Elias PM. Recessive x-linked ichthyosis: role of cholesterol-sulfate accumulation in the barrier abnormality. J Invest Dermatol. 1998 Nov; 111(5):784-90. PMID: 9804339.
      View in: PubMed
    25. Ghadially R. Aging and the epidermal permeability barrier: implications for contact dermatitis. Am J Contact Dermat. 1998 Sep; 9(3):162-9. PMID: 9744909.
      View in: PubMed
    26. Zettersten EM, Ghadially R, Feingold KR, Crumrine D, Elias PM. Optimal ratios of topical stratum corneum lipids improve barrier recovery in chronologically aged skin. J Am Acad Dermatol. 1997 Sep; 37(3 Pt 1):403-8. PMID: 9308554.
      View in: PubMed
    27. Ghadially R, Reed JT, Elias PM. Stratum corneum structure and function correlates with phenotype in psoriasis. J Invest Dermatol. 1996 Oct; 107(4):558-64. PMID: 8823361.
      View in: PubMed
    28. Ghadially R, Brown BE, Hanley K, Reed JT, Feingold KR, Elias PM. Decreased epidermal lipid synthesis accounts for altered barrier function in aged mice. J Invest Dermatol. 1996 May; 106(5):1064-9. PMID: 8618040.
      View in: PubMed
    29. Ghadially FN, Ghadially R. Tumours of the skin. IARC Sci Publ. 1996; (126):1-43. PMID: 8875259.
      View in: PubMed
    30. Reed JT, Ghadially R, Elias PM. Skin type, but neither race nor gender, influence epidermal permeability barrier function. Arch Dermatol. 1995 Oct; 131(10):1134-8. PMID: 7574829.
      View in: PubMed
    31. Ghadially R, Brown BE, Sequeira-Martin SM, Feingold KR, Elias PM. The aged epidermal permeability barrier. Structural, functional, and lipid biochemical abnormalities in humans and a senescent murine model. J Clin Invest. 1995 May; 95(5):2281-90. PMID: 7738193; PMCID: PMC295841.
    32. Ghadially R, Williams ML, Hou SY, Elias PM. Membrane structural abnormalities in the stratum corneum of the autosomal recessive ichthyoses. J Invest Dermatol. 1992 Dec; 99(6):755-63. PMID: 1469289.
      View in: PubMed
    33. Williams ML, Vogel JS, Ghadially R, Brown BE, Elias PM. Exogenous origin of n-alkanes in pathologic scale. Arch Dermatol. 1992 Aug; 128(8):1065-71. PMID: 1497360.
      View in: PubMed
    34. Ghadially R, Chong LP. Ichthyoses and hyperkeratotic disorders. Dermatol Clin. 1992 Jul; 10(3):597-607. PMID: 1617817.
      View in: PubMed
    35. Menon GK, Ghadially R, Williams ML, Elias PM. Lamellar bodies as delivery systems of hydrolytic enzymes: implications for normal and abnormal desquamation. Br J Dermatol. 1992 Apr; 126(4):337-45. PMID: 1571254.
      View in: PubMed
    36. Ghadially R, Halkier-Sorensen L, Elias PM. Effects of petrolatum on stratum corneum structure and function. J Am Acad Dermatol. 1992 Mar; 26(3 Pt 2):387-96. PMID: 1564142.
      View in: PubMed
    37. Hou SY, Mitra AK, White SH, Menon GK, Ghadially R, Elias PM. Membrane structures in normal and essential fatty acid-deficient stratum corneum: characterization by ruthenium tetroxide staining and x-ray diffraction. J Invest Dermatol. 1991 Feb; 96(2):215-23. PMID: 1991982.
      View in: PubMed
    38. Ghadially R, Ghadially FN. Anchoring fibrils in a spindle cell squamous carcinoma. J Submicrosc Cytol Pathol. 1989 Apr; 21(2):249-57. PMID: 2752358.
      View in: PubMed
    39. Braganca BM, Sambray YM, Ghadially RC. Simple method for purification of phospholipase A from cobra venom. Toxicon. 1969 Sep; 7(2):151-7. PMID: 5387831.
      View in: PubMed
    40. JOHNSTON JA, GHADIALLY RC, ROBERTS RN, FUHR BW. Myo-Inositol activity of oxidtion products derived from myo-inositol. Arch Biochem Biophys. 1962 Dec; 99:537-8. PMID: 13957897.
      View in: PubMed
    Ruby's Networks
    Concepts
    Derived automatically from this person's publications.
    _
    Co-Authors
    People in Profiles who have published with this person.
    _
    Related Authors
    People who share related concepts with this person.
    _
    Back to TOP