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    Ryan Coleman, PhD

    TitlePostdoctoral Scholar
    SchoolUCSF School of Pharmacy
    DepartmentPharmaceutical Chemistry
    AddressQB3 Fifth Floor North
    San Francisco CA

       Bibliographic 
       Publications
      Publications by year:
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      1. Cameron RT, Coleman RG, Day JP, Yalla KC, Houslay MD, Adams DR, Shoichet BK, Baillie GS. Chemical informatics uncovers a new role for moexipril as a novel inhibitor of cAMP phosphodiesterase-4 (PDE4). Biochem Pharmacol. 2013 May 1; 85(9):1297-305.
        View in: PubMed
      2. Irwin JJ, Sterling T, Mysinger MM, Bolstad ES, Coleman RG. ZINC: A Free Tool to Discover Chemistry for Biology. J Chem Inf Model. 2012 Jun 15.
        View in: PubMed
      3. Carlsson J, Coleman RG, Setola V, Irwin JJ, Fan H, Schlessinger A, Sali A, Roth BL, Shoichet BK. Ligand discovery from a dopamine D3 receptor homology model and crystal structure. Nat Chem Biol. 2011 Nov; 7(11):769-78.
        View in: PubMed
      4. Coleman RG, Sharp KA. Protein pockets: inventory, shape, and comparison. J Chem Inf Model. 2010 Apr 26; 50(4):589-603.
        View in: PubMed
      5. Coleman RG, Sharp KA. Shape and evolution of thermostable protein structure. Proteins. 2010 Feb 1; 78(2):420-33.
        View in: PubMed
      6. Coleman RG, Sharp KA. Finding and characterizing tunnels in macromolecules with application to ion channels and pores. Biophys J. 2009 Jan; 96(2):632-45.
        View in: PubMed
      7. Cheng AC, Coleman RG, Smyth KT, Cao Q, Soulard P, Caffrey DR, Salzberg AC, Huang ES. Structure-based maximal affinity model predicts small-molecule druggability. Nat Biotechnol. 2007 Jan; 25(1):71-5.
        View in: PubMed
      8. Coleman RG, Salzberg AC, Cheng AC. Structure-based identification of small molecule binding sites using a free energy model. J Chem Inf Model. 2006 Nov-Dec; 46(6):2631-7.
        View in: PubMed
      9. Zelent B, Vanderkooi JM, Coleman RG, Gryczynski I, Gryczynski Z. Protonation of excited state pyrene-1-carboxylate by phosphate and organic acids in aqueous solution studied by fluorescence spectroscopy. Biophys J. 2006 Nov 15; 91(10):3864-71.
        View in: PubMed
      10. Coleman RG, Sharp KA. Travel depth, a new shape descriptor for macromolecules: application to ligand binding. J Mol Biol. 2006 Sep 22; 362(3):441-58.
        View in: PubMed
      11. Coleman RG, Burr MA, Souvaine DL, Cheng AC. An intuitive approach to measuring protein surface curvature. Proteins. 2005 Dec 1; 61(4):1068-74.
        View in: PubMed
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