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    Santhosh Sivaramakrishnan, PhD

    TitlePostdoctoral Scholar
    SchoolUCSF School of Pharmacy
    DepartmentPharmaceutical Chemistry
    Address600 16th Street
    San Francisco CA 94158
    Phone415-476-4420

       Bibliographic 
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      1. Sivaramakrishnan S, Breydo L, Sun D, Gates KS. The macrocycle of leinamycin imparts hydrolytic stability to the thiol-sensing 1,2-dithiolan-3-one 1-oxide unit of the natural product. Bioorg Med Chem Lett. 2012 Jun 1; 22(11):3791-4.
        View in: PubMed
      2. Sivaramakrishnan S, Ouellet H, Matsumura H, Guan S, Moënne-Loccoz P, Burlingame AL, Ortiz de Montellano PR. Proximal ligand electron donation and reactivity of the cytochrome P450 ferric-peroxo anion. J Am Chem Soc. 2012 Apr 18; 134(15):6673-84.
        View in: PubMed
      3. Sivaramakrishnan S, Ouellet H, Du J, McLean KJ, Medzihradszky KF, Dawson JH, Munro AW, Ortiz de Montellano PR. A novel intermediate in the reaction of seleno CYP119 with m-chloroperbenzoic acid. Biochemistry. 2011 Apr 12; 50(14):3014-24.
        View in: PubMed
      4. Yukl ET, Ioanoviciu A, Sivaramakrishnan S, Nakano MM, Ortiz de Montellano PR, Moënne-Loccoz P. Nitric oxide dioxygenation reaction in DevS and the initial response to nitric oxide in Mycobacterium tuberculosis. Biochemistry. 2011 Feb 15; 50(6):1023-8.
        View in: PubMed
      5. Lampe JN, Brandman R, Sivaramakrishnan S, de Montellano PR. Two-dimensional NMR and all-atom molecular dynamics of cytochrome P450 CYP119 reveal hidden conformational substates. J Biol Chem. 2010 Mar 26; 285(13):9594-603.
        View in: PubMed
      6. Sivaramakrishnan S, Cummings AH, Gates KS. Protection of a single-cysteine redox switch from oxidative destruction: On the functional role of sulfenyl amide formation in the redox-regulated enzyme PTP1B. Bioorg Med Chem Lett. 2010 Jan 15; 20(2):444-7.
        View in: PubMed
      7. Jiang Y, Sivaramakrishnan S, Hayashi T, Cohen S, Moënne-Loccoz P, Shaik S, Ortiz de Montellano PR. Calculated and experimental spin state of seleno cytochrome P450. Angew Chem Int Ed Engl. 2009; 48(39):7193-5.
        View in: PubMed
      8. Keerthi K, Sivaramakrishnan S, Gates KS. Evidence for a Morin type intramolecular cyclization of an alkene with a phenylsulfenic acid group in neutral aqueous solution. Chem Res Toxicol. 2008 Jul; 21(7):1368-74.
        View in: PubMed
      9. Sivaramakrishnan S, Gates KS. Possible chemical mechanisms underlying the antitumor activity of S-deoxyleinamycin. Bioorg Med Chem Lett. 2008 May 15; 18(10):3076-80.
        View in: PubMed
      10. Sivaramakrishnan S, Keerthi K, Gates KS. A chemical model for redox regulation of protein tyrosine phosphatase 1B (PTP1B) activity. J Am Chem Soc. 2005 Aug 10; 127(31):10830-1.
        View in: PubMed
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