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Scott Soifer, MD

TitleProfessor
SchoolUCSF School of Medicine
DepartmentPediatrics
Address550 16th. Street
San Francisco CA 94158
Phone415-476-6083
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidency School of Medicine

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    ABNORMAL FETAL LUNG CIRCULATION--VASOACTIVE MEDIATORS
    NIH/NHLBI R01HL035518Jul 1, 1986 - May 31, 2000
    Role: Principal Investigator
    PULMONARY HYPERTENSION AND LUNG DISEASE IN THE NEWBORN
    NIH/NHLBI R23HL029941Jan 1, 1983 - Dec 31, 1985
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Rouine-Rapp K, Mello DM, Hanley FL, Mohan Reddy V, Soifer S. Effect of enalaprilat on postoperative hypertension after surgical repair of coarctation of the aorta. Pediatr Crit Care Med. 2003 Jul; 4(3):327-32. PMID: 12831415.
      View in: PubMed
    2. Mata-Greenwood E, Meyrick B, Soifer SJ, Fineman JR, Black SM. Expression of VEGF and its receptors Flt-1 and Flk-1/KDR is altered in lambs with increased pulmonary blood flow and pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2003 Jul; 285(1):L222-31. PMID: 12665467.
      View in: PubMed
    3. Quinn TP, Schlueter M, Soifer SJ, Gutierrez JA. Cyclic mechanical stretch induces VEGF and FGF-2 expression in pulmonary vascular smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2002 May; 282(5):L897-903. PMID: 11943652.
      View in: PubMed
    4. Quinn TP, Soifer SJ, Ramer K, Williams LT, Nakamura MC. A receptor for vascular endothelial growth factor that stimulates endothelial apoptosis. Cancer Res. 2001 Dec 15; 61(24):8629-37. PMID: 11751375.
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    5. Black SM, Bekker JM, Johengen MJ, Parry AJ, Soifer SJ, Fineman JR. Altered regulation of the ET-1 cascade in lambs with increased pulmonary blood flow and pulmonary hypertension. Pediatr Res. 2000 Jan; 47(1):97-106. PMID: 10625089.
      View in: PubMed
    6. Fineman JR, Wong J, Mikhailov T, Vanderford PA, Jerome HE, Soifer SJ. Altered endothelial function in lambs with pulmonary hypertension and acute lung injury. Pediatr Pulmonol. 1999 Mar; 27(3):147-56. PMID: 10213252.
      View in: PubMed
    7. Black SM, Johengen MJ, Soifer SJ. Coordinated regulation of genes of the nitric oxide and endothelin pathways during the development of pulmonary hypertension in fetal lambs. Pediatr Res. 1998 Dec; 44(6):821-30. PMID: 9853913.
      View in: PubMed
    8. Black SM, Fineman JR, Steinhorn RH, Bristow J, Soifer SJ. Increased endothelial NOS in lambs with increased pulmonary blood flow and pulmonary hypertension. Am J Physiol. 1998 Nov; 275(5 Pt 2):H1643-51. PMID: 9815072.
      View in: PubMed
    9. Black S, Fineman J, Johengen M, Bristow J, Soifer S. Increased pulmonary blood flow alters the molecular regulation of vascular reactivity in the lamb. Chest. 1998 Jul; 114(1 Suppl):39S. PMID: 9676621.
      View in: PubMed
    10. Black SM, Johengen MJ, Ma ZD, Bristow J, Soifer SJ. Ventilation and oxygenation induce endothelial nitric oxide synthase gene expression in the lungs of fetal lambs. J Clin Invest. 1997 Sep 15; 100(6):1448-58. PMID: 9294110; PMCID: PMC508323.
    11. Black SM, Bedolli MA, Martinez S, Bristow JD, Ferriero DM, Soifer SJ. Expression of neuronal nitric oxide synthase corresponds to regions of selective vulnerability to hypoxia-ischaemia in the developing rat brain. Neurobiol Dis. 1995 Jun; 2(3):145-55. PMID: 9173998.
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    12. Wong J, Vanderford PA, Winters J, Soifer SJ, Fineman JR. Endothelinb receptor agonists produce pulmonary vasodilation in intact newborn lambs with pulmonary hypertension. J Cardiovasc Pharmacol. 1995 Feb; 25(2):207-15. PMID: 7752646.
      View in: PubMed
    13. Fineman JR, Soifer SJ, Heymann MA. Regulation of pulmonary vascular tone in the perinatal period. Annu Rev Physiol. 1995; 57:115-34. PMID: 7778860.
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    14. Brook MM, Fineman JR, Bolinger AM, Wong AF, Heymann MA, Soifer SJ. Use of ATP-MgCl2 in the evaluation and treatment of children with pulmonary hypertension secondary to congenital heart defects. Circulation. 1994 Sep; 90(3):1287-93. PMID: 8087937.
      View in: PubMed
    15. Wong J, Vanderford PA, Fineman JR, Soifer SJ. Developmental effects of endothelin-1 on the pulmonary circulation in sheep. Pediatr Res. 1994 Sep; 36(3):394-401. PMID: 7808838.
      View in: PubMed
    16. Fineman JR, Wong J, Morin FC, Wild LM, Soifer SJ. Chronic nitric oxide inhibition in utero produces persistent pulmonary hypertension in newborn lambs. J Clin Invest. 1994 Jun; 93(6):2675-83. PMID: 8201005; PMCID: PMC294514.
    17. Crowley MR, Fineman JR, Soifer SJ. HA1004, an intracellular calcium antagonist, selectively attenuates pulmonary hypertension in newborn lambs. J Cardiovasc Pharmacol. 1994 May; 23(5):806-13. PMID: 7521465.
      View in: PubMed
    18. Vanderford PA, Wong J, Chang R, Keefer LK, Soifer SJ, Fineman JR. Diethylamine/nitric oxide (NO) adduct, an NO donor, produces potent pulmonary and systemic vasodilation in intact newborn lambs. J Cardiovasc Pharmacol. 1994 Jan; 23(1):113-9. PMID: 7511722.
      View in: PubMed
    19. Soifer SJ, Peters KG, O'Keefe J, Coughlin SR. Disparate temporal expression of the prothrombin and thrombin receptor genes during mouse development. Am J Pathol. 1994 Jan; 144(1):60-9. PMID: 8291612; PMCID: PMC1887128.
    20. Wong J, Vanderford PA, Fineman JR, Chang R, Soifer SJ. Endothelin-1 produces pulmonary vasodilation in the intact newborn lamb. Am J Physiol. 1993 Oct; 265(4 Pt 2):H1318-25. PMID: 8238420.
      View in: PubMed
    21. Soifer SJ. Pulmonary hypertension: physiologic or pathologic disease? Crit Care Med. 1993 Sep; 21(9 Suppl):S370-4. PMID: 8365235.
      View in: PubMed
    22. Fineman JR, Wong J, Soifer SJ. Hyperoxia and alkalosis produce pulmonary vasodilation independent of endothelium-derived nitric oxide in newborn lambs. Pediatr Res. 1993 Apr; 33(4 Pt 1):341-6. PMID: 8479813.
      View in: PubMed
    23. Braner DA, Fineman JR, Chang R, Soifer SJ. M&B 22948, a cGMP phosphodiesterase inhibitor, is a pulmonary vasodilator in lambs. Am J Physiol. 1993 Jan; 264(1 Pt 2):H252-8. PMID: 8381611.
      View in: PubMed
    24. Wong J, Vanderford PA, Winters JW, Chang R, Soifer SJ, Fineman JR. Endothelin-1 does not mediate acute hypoxic pulmonary vasoconstriction in the intact newborn lamb. J Cardiovasc Pharmacol. 1993; 22 Suppl 8:S262-6. PMID: 7509961.
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    25. Moore P, Velvis H, Fineman JR, Soifer SJ, Heymann MA. EDRF inhibition attenuates the increase in pulmonary blood flow due to oxygen ventilation in fetal lambs. J Appl Physiol (1985). 1992 Nov; 73(5):2151-7. PMID: 1474097.
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    26. Nelken NA, Soifer S, O'Keefe J, Vu TK, Charo IF, Coughlin SR. Thrombin receptor expression in normal and atherosclerotic human arteries. J Clin Invest. 1992 Oct; 90(4):1614-21. PMID: 1328304; PMCID: PMC443210.
    27. Chang JK, Moore P, Fineman JR, Soifer S, Heymann MA. K+ channel pulmonary vasodilation in fetal lambs: role of endothelium-derived nitric oxide. J Appl Physiol (1985). 1992 Jul; 73(1):188-94. PMID: 1506367.
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    28. Fineman JR, Chang R, Soifer S. EDRF inhibition augments pulmonary hypertension in intact newborn lambs. Am J Physiol. 1992 May; 262(5 Pt 2):H1365-71. PMID: 1590440.
      View in: PubMed
    29. Fineman JR, Chang R, Soifer S. L-Arginine, a precursor of EDRF in vitro, produces pulmonary vasodilation in lambs. Am J Physiol. 1991 Nov; 261(5 Pt 2):H1563-9. PMID: 1659228.
      View in: PubMed
    30. Schreiber MD, Soifer S. Hemodynamic effects of oleic acid in newborn lambs: role of arachidonic acid metabolites. J Dev Physiol. 1991 Sep; 16(3):167-72. PMID: 1797924.
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    31. Fineman JR, Crowley MR, Heymann MA, Soifer S. In vivo attenuation of endothelium-dependent pulmonary vasodilation by methylene blue. J Appl Physiol (1985). 1991 Aug; 71(2):735-41. PMID: 1657862.
      View in: PubMed
    32. Fineman JR, Heymann MA, Soifer S. N omega-nitro-L-arginine attenuates endothelium-dependent pulmonary vasodilation in lambs. Am J Physiol. 1991 Apr; 260(4 Pt 2):H1299-306. PMID: 1849373.
      View in: PubMed
    33. Fineman JR, Soifer S, Heymann MA. The role of pulmonary vascular endothelium in perinatal pulmonary circulatory regulation. Semin Perinatol. 1991 Feb; 15(1):58-62. PMID: 2063230.
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    34. Crowley MR, Fineman JR, Soifer S. Effects of vasoactive drugs on thromboxane A2 mimetic-induced pulmonary hypertension in newborn lambs. Pediatr Res. 1991 Feb; 29(2):167-72. PMID: 2014153.
      View in: PubMed
    35. Fineman JR, Crowley MR, Soifer SJ. Selective pulmonary vasodilation with ATP-MgCl2 during pulmonary hypertension in lambs. J Appl Physiol (1985). 1990 Nov; 69(5):1836-42. PMID: 2272976.
      View in: PubMed
    36. Velvis H, Krusell J, Roman C, Soifer S, Riemer RK, Heymann MA. Leukotrienes C4, D4, and E4 in fetal lamb tracheal fluid. J Dev Physiol. 1990 Jul; 14(1):37-41. PMID: 1965438.
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    37. Andropoulos DB, Soifer S, Schreiber MD. Plasma epinephrine concentrations after intraosseous and central venous injection during cardiopulmonary resuscitation in the lamb. J Pediatr. 1990 Feb; 116(2):312-5. PMID: 2299508.
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    38. Frantz E, Soifer SJ, Clyman RI, Heymann MA. Bradykinin produces pulmonary vasodilation in fetal lambs: role of prostaglandin production. J Appl Physiol (1985). 1989 Oct; 67(4):1512-7. PMID: 2507510.
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    39. Soifer S, Schreiber MD, Heymann MA. Leukotriene antagonists attenuate thromboxane-inducible pulmonary hypertension. Pediatr Res. 1989 Aug; 26(2):83-7. PMID: 2505220.
      View in: PubMed
    40. Frantz EG, Schreiber MD, Soifer S. Cromolyn sodium does not prevent hypoxia-induced pulmonary hypertension in newborn and young lambs. J Dev Physiol. 1988 Dec; 10(6):555-65. PMID: 3149968.
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    41. Schreiber MD, Soifer SJ. Respiratory alkalosis attenuates thromboxane-induced pulmonary hypertension. Crit Care Med. 1988 Dec; 16(12):1225-8. PMID: 3191739.
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    42. Martin GR, Silverman NH, Soifer SJ, Lutin WA, Scagnelli SA. Tricuspid regurgitation in children: a pulsed Doppler, contrast echocardiographic and angiographic comparison. J Am Soc Echocardiogr. 1988 Jul-Aug; 1(4):257-63. PMID: 3272773.
      View in: PubMed
    43. Soifer SJ, Clyman RI, Heymann MA. Effects of prostaglandin D2 on pulmonary arterial pressure and oxygenation in newborn infants with persistent pulmonary hypertension. J Pediatr. 1988 May; 112(5):774-7. PMID: 3162978.
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    44. Heymann MA, LeBidois J, Soifer S, Clyman RI. Leukotriene synthesis inhibition increases pulmonary blood flow in fetal lambs. Chest. 1988 Mar; 93(3 Suppl):117S. PMID: 3125017.
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    45. Lebidois J, Soifer SJ, Clyman RI, Heymann MA. Piriprost: a putative leukotriene synthesis inhibitor increases pulmonary blood flow in fetal lambs. Pediatr Res. 1987 Sep; 22(3):350-4. PMID: 3309861.
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    46. Soifer S, Kaslow D, Roman C, Heymann MA. Umbilical cord compression produces pulmonary hypertension in newborn lambs: a model to study the pathophysiology of persistent pulmonary hypertension in the newborn. J Dev Physiol. 1987 Jun; 9(3):239-52. PMID: 3112213.
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    47. Martin GR, Soifer SJ, Silverman NH, Dae MW, Stanger P. Effects of activity on ascending aortic velocity in children with valvar aortic stenosis. Am J Cardiol. 1987 Jun 01; 59(15):1386-90. PMID: 3591696.
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    48. Schreiber MD, Heymann MA, Soifer SJ. The differential effects of leukotriene C4 and D4 on the pulmonary and systemic circulations in newborn lambs. Pediatr Res. 1987 Feb; 21(2):176-82. PMID: 3822598.
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    49. Yee ES, Soifer SJ, Turley K, Verrier ED, Fishman NH, Ebert PA. Infant coarctation: a spectrum in clinical presentation and treatment. Ann Thorac Surg. 1986 Nov; 42(5):488-93. PMID: 3777999.
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    50. Schreiber MD, Heymann MA, Soifer S. Increased arterial pH, not decreased PaCO2, attenuates hypoxia-induced pulmonary vasoconstriction in newborn lambs. Pediatr Res. 1986 Feb; 20(2):113-7. PMID: 3080725.
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    51. Martin GR, Cooper MJ, Silverman NH, Soifer SJ. Contrast echocardiography in the diagnosis of anomalous left coronary artery arising from the pulmonary artery. Pediatr Cardiol. 1986; 6(4):203-5. PMID: 3703691.
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    52. Clozel M, Clyman RI, Soifer SJ, Heymann MA. Thromboxane is not responsible for the high pulmonary vascular resistance in fetal lambs. Pediatr Res. 1985 Dec; 19(12):1254-7. PMID: 4080442.
      View in: PubMed
    53. Soifer SJ, Loitz RD, Roman C, Heymann MA. Leukotriene end organ antagonists increase pulmonary blood flow in fetal lambs. Am J Physiol. 1985 Sep; 249(3 Pt 2):H570-6. PMID: 4037105.
      View in: PubMed
    54. Schreiber MD, Heymann MA, Soifer SJ. Leukotriene inhibition prevents and reverses hypoxic pulmonary vasoconstriction in newborn lambs. Pediatr Res. 1985 May; 19(5):437-41. PMID: 4000769.
      View in: PubMed
    55. Soifer SJ, Heymann MA. Future research directions in persistent pulmonary hypertension of the newborn. Clin Perinatol. 1984 Oct; 11(3):745-55. PMID: 6386274.
      View in: PubMed
    56. Yee ES, Turley K, Soifer S, Ebert PA. Synthetic patch aortoplasty. A simplified approach for coarctation in repairs during early infancy and thereafter. Am J Surg. 1984 Aug; 148(2):240-3. PMID: 6380324.
      View in: PubMed
    57. Soifer SJ, Morin FC, Kaslow DC, Heymann MA. The developmental effects of prostaglandin D2 on the pulmonary and systemic circulations in the newborn lamb. J Dev Physiol. 1983 Aug; 5(4):237-50. PMID: 6579103.
      View in: PubMed
    58. Soifer SJ, Morin FC, Heymann MA. Prostaglandin D2 reverses induced pulmonary hypertension in the newborn lamb. J Pediatr. 1982 Mar; 100(3):458-63. PMID: 7199569.
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    59. Snider AR, Soifer SJ, Silverman NH. Detection of intracranial arteriovenous fistula by two-dimensional ultrasonography. Circulation. 1981 May; 63(5):1179-85. PMID: 6451332.
      View in: PubMed
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