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Sergio Peisajovich

TitlePostdoctoral Scholar Employee
SchoolUCSF School of Medicine
DepartmentGladstone Institutes
Address600 16th Street
San Francisco CA 94158
Phone415-502-8133
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Di Roberto RB, Scott BM, Peisajovich SG. Directed Evolution Methods to Rewire Signaling Networks. Methods Mol Biol. 2017; 1596:321-337. PMID: 28293896.
      View in: PubMed
    2. Kompella PS, Moses AM, Peisajovich SG. Introduction of Premature Stop Codons as an Evolutionary Strategy To Rescue Signaling Network Function. ACS Synth Biol. 2017 Mar 17; 6(3):446-454. PMID: 27935292.
      View in: PubMed
    3. Di Roberto RB, Chang B, Trusina A, Peisajovich SG. Evolution of a G protein-coupled receptor response by mutations in regulatory network interactions. Nat Commun. 2016 Aug 04; 7:12344. PMID: 27487915; PMCID: PMC4976203.
    4. Lai A, Sato PM, Peisajovich SG. Evolution of synthetic signaling scaffolds by recombination of modular protein domains. ACS Synth Biol. 2015 Jun 19; 4(6):714-22. PMID: 25587847.
      View in: PubMed
    5. Sato PM, Yoganathan K, Jung JH, Peisajovich SG. The robustness of a signaling complex to domain rearrangements facilitates network evolution. PLoS Biol. 2014 Dec; 12(12):e1002012. PMID: 25490747; PMCID: PMC4260825.
    6. Thattai M, Peisajovich SG. Current approaches in evolution: from molecules to cells and organisms. J Exp Zool B Mol Dev Evol. 2014 Nov; 322(7):465-7. PMID: 25045153.
      View in: PubMed
    7. Di Roberto RB, Peisajovich SG. The role of domain shuffling in the evolution of signaling networks. J Exp Zool B Mol Dev Evol. 2014 Feb; 322(2):65-72. PMID: 24255009.
      View in: PubMed
    8. Wei P, Wong WW, Park JS, Corcoran EE, Peisajovich SG, Onuffer JJ, Weiss A, Lim WA. Bacterial virulence proteins as tools to rewire kinase pathways in yeast and immune cells. Nature. 2012 Aug 16; 488(7411):384-8. PMID: 22820255; PMCID: PMC3422413.
    9. Peisajovich SG. Evolutionary synthetic biology. ACS Synth Biol. 2012 Jun 15; 1(6):199-210. PMID: 23651203.
      View in: PubMed
    10. Peisajovich SG, Garbarino JE, Wei P, Lim WA. Rapid diversification of cell signaling phenotypes by modular domain recombination. Science. 2010 Apr 16; 328(5976):368-72. PMID: 20395511; PMCID: PMC2975375.
    11. Bashor CJ, Horwitz AA, Peisajovich SG, Lim WA. Rewiring cells: synthetic biology as a tool to interrogate the organizational principles of living systems. Annu Rev Biophys. 2010; 39:515-37. PMID: 20192780; PMCID: PMC2965450.
    12. Peisajovich SG, Tawfik DS. Protein engineers turned evolutionists. Nat Methods. 2007 Dec; 4(12):991-4. PMID: 18049465.
      View in: PubMed
    13. Williams R, Peisajovich SG, Miller OJ, Magdassi S, Tawfik DS, Griffiths AD. Amplification of complex gene libraries by emulsion PCR. Nat Methods. 2006 Jul; 3(7):545-50. PMID: 16791213.
      View in: PubMed
    14. Peisajovich SG, Rockah L, Tawfik DS. Evolution of new protein topologies through multistep gene rearrangements. Nat Genet. 2006 Feb; 38(2):168-74. PMID: 16415885.
      View in: PubMed
    15. Peisajovich SG, Shai Y. Viral fusion proteins: multiple regions contribute to membrane fusion. Biochim Biophys Acta. 2003 Jul 11; 1614(1):122-9. PMID: 12873773.
      View in: PubMed
    16. Peisajovich SG, Gallo SA, Blumenthal R, Shai Y. C-terminal octylation rescues an inactive T20 mutant: implications for the mechanism of HIV/SIMIAN immunodeficiency virus-induced membrane fusion. J Biol Chem. 2003 Jun 06; 278(23):21012-7. PMID: 12646555.
      View in: PubMed
    17. Peisajovich SG, Blank L, Epand RF, Epand RM, Shai Y. On the interaction between gp41 and membranes: the immunodominant loop stabilizes gp41 helical hairpin conformation. J Mol Biol. 2003 Mar 07; 326(5):1489-501. PMID: 12595260.
      View in: PubMed
    18. Peisajovich SG, Shai Y. Liposomes in identification and characterization of viral fusogenic peptides. Methods Enzymol. 2003; 372:361-73. PMID: 14610824.
      View in: PubMed
    19. Peisajovich SG, Epand RF, Epand RM, Shai Y. Sendai virus N-terminal fusion peptide consists of two similar repeats, both of which contribute to membrane fusion. Eur J Biochem. 2002 Sep; 269(17):4342-50. PMID: 12199713.
      View in: PubMed
    20. Peisajovich SG, Shai Y. New insights into the mechanism of virus-induced membrane fusion. Trends Biochem Sci. 2002 Apr; 27(4):183-90. PMID: 11943545.
      View in: PubMed
    21. Peisajovich SG, Shai Y. High similarity between reverse-oriented sequences from HIV and foamy virus envelope glycoproteins. AIDS Res Hum Retroviruses. 2002 Mar 01; 18(4):309-12. PMID: 11860678.
      View in: PubMed
    22. Peisajovich SG, Shai Y. SIV gp41 binds to membranes both in the monomeric and trimeric states: consequences for the neuropathology and inhibition of HIV infection. J Mol Biol. 2001 Aug 10; 311(2):249-54. PMID: 11478858.
      View in: PubMed
    23. Kliger Y, Gallo SA, Peisajovich SG, Munoz-Barroso I, Avkin S, Blumenthal R, Shai Y. Mode of action of an antiviral peptide from HIV-1. Inhibition at a post-lipid mixing stage. J Biol Chem. 2001 Jan 12; 276(2):1391-7. PMID: 11027678.
      View in: PubMed
    24. Ghosh JK, Peisajovich SG, Shai Y. Sendai virus internal fusion peptide: structural and functional characterization and a plausible mode of viral entry inhibition. Biochemistry. 2000 Sep 26; 39(38):11581-92. PMID: 10995225.
      View in: PubMed
    25. Kliger Y, Peisajovich SG, Blumenthal R, Shai Y. Membrane-induced conformational change during the activation of HIV-1 gp41. J Mol Biol. 2000 Aug 25; 301(4):905-14. PMID: 10966795.
      View in: PubMed
    26. Peisajovich SG, Samuel O, Shai Y. Paramyxovirus F1 protein has two fusion peptides: implications for the mechanism of membrane fusion. J Mol Biol. 2000 Mar 10; 296(5):1353-65. PMID: 10698638.
      View in: PubMed
    27. Peisajovich SG, Epand RF, Pritsker M, Shai Y, Epand RM. The polar region consecutive to the HIV fusion peptide participates in membrane fusion. Biochemistry. 2000 Feb 22; 39(7):1826-33. PMID: 10677233.
      View in: PubMed
    28. Clérico EM, Peisajovich SG, Ceolín M, Ghiringhelli PD, Ermácora MR. Engineering a compact non-native state of intestinal fatty acid-binding protein. Biochim Biophys Acta. 2000 Feb 09; 1476(2):203-18. PMID: 10669786.
      View in: PubMed
    29. Ghosh JK, Peisajovich SG, Ovadia M, Shai Y. Structure-function study of a heptad repeat positioned near the transmembrane domain of Sendai virus fusion protein which blocks virus-cell fusion. J Biol Chem. 1998 Oct 16; 273(42):27182-90. PMID: 9765238.
      View in: PubMed
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