Simon Cleary, PhD

Title(s)Specialist, Medicine
SchoolSchool of Medicine
Address513 Parnassus Ave, HSE, #1355A
San Francisco CA 94143
Phone415-514-4180
ORCID ORCID Icon0000-0001-5573-6363 Additional info
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. IgG hexamers initiate complement-dependent acute lung injury. J Clin Invest. 2024 Mar 26. Cleary SJ, Seo Y, Tian JJ, Kwaan N, Bulkley DP, Bentlage AEH, Vidarsson G, Boilard É, Spirig R, Zimring JC, Looney MR. PMID: 38530369.
      View in: PubMed   Mentions:    Fields:    
    2. Decoding functional hematopoietic progenitor cells in the adult human lung. Res Sq. 2024 Feb 16. Conrad C, Magnen M, Tsui J, Wismer H, Naser M, Venkataramani U, Samad B, Cleary SJ, Qiu L, Tian JJ, De Giovanni M, Mende N, Passegue E, Laurenti E, Combes AJ, Looney MR. PMID: 38077002; PMCID: PMC10705601.
      View in: PubMed   Mentions:
    3. IgG hexamers initiate acute lung injury. bioRxiv. 2024 Jan 27. Cleary SJ, Seo Y, Tian JJ, Kwaan N, Bulkley DP, Bentlage AEH, Vidarsson G, Boilard É, Spirig R, Zimring JC, Looney MR. PMID: 38328049; PMCID: PMC10849723.
      View in: PubMed   Mentions:
    4. CCR5 drives NK cell-associated airway damage in pulmonary ischemia-reperfusion injury. JCI Insight. 2023 Nov 08; 8(21). Santos J, Wang P, Shemesh A, Liu F, Tsao T, Aguilar OA, Cleary SJ, Singer JP, Gao Y, Hays SR, Golden JA, Leard L, Kleinhenz ME, Kolaitis NA, Shah R, Venado A, Kukreja J, Weigt SS, Belperio JA, Lanier LL, Looney MR, Greenland JR, Calabrese DR. PMID: 37788115; PMCID: PMC10721259.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    5. Optimizing anesthesia and delivery approaches for dosing into lungs of mice. Am J Physiol Lung Cell Mol Physiol. 2023 08 01; 325(2):L262-L269. Seo Y, Qiu L, Magnen M, Conrad C, Moussavi-Harami SF, Looney MR, Cleary SJ. PMID: 37401383; PMCID: PMC10625824.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    6. Optimizing anesthesia and delivery approaches for dosing into lungs of mice. bioRxiv. 2023 Jun 29. Seo Y, Qiu L, Magnen M, Conrad C, Moussavi-Harami SF, Looney MR, Cleary SJ. PMID: 36778478; PMCID: PMC9915691.
      View in: PubMed   Mentions:
    7. Investigating and imaging platelets in inflammation. Int J Biochem Cell Biol. 2023 04; 157:106373. Cleary SJ, Conrad C. PMID: 36716816.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    8. Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression. J Clin Invest. 2022 04 01; 132(7). Valet C, Magnen M, Qiu L, Cleary SJ, Wang KM, Ranucci S, Grockowiak E, Boudra R, Conrad C, Seo Y, Calabrese DR, Greenland JR, Leavitt AD, Passegué E, Méndez-Ferrer S, Swirski FK, Looney MR. PMID: 35192546; PMCID: PMC8970674.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    9. ADAM8 signaling drives neutrophil migration and ARDS severity. JCI Insight. 2022 02 08; 7(3). Conrad C, Yildiz D, Cleary SJ, Margraf A, Cook L, Schlomann U, Panaretou B, Bowser JL, Karmouty-Quintana H, Li J, Berg NK, Martin SC, Aljohmani A, Moussavi-Harami SF, Wang KM, Tian JJ, Magnen M, Valet C, Qiu L, Singer JP, Eltzschig HK, CAPSys Study Group, Bertrams W, Herold S, Suttorp N, Schmeck B, Ball ZT, Zarbock A, Looney MR, Bartsch JW. PMID: 35132956; PMCID: PMC8855804.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    10. In Vivo Measurement of Granzyme Proteolysis from Activated Immune Cells with PET. ACS Cent Sci. 2021 Oct 27; 7(10):1638-1649. Zhao N, Bardine C, Lourenço AL, Wang YH, Huang Y, Cleary SJ, Wilson DM, Oh DY, Fong L, Looney MR, Evans MJ, Craik CS. PMID: 34729407; PMCID: PMC8554823.
      View in: PubMed   Mentions: 18  
    11. The GPCR adaptor protein norbin suppresses the neutrophil-mediated immunity of mice to pneumococcal infection. Blood Adv. 2021 08 24; 5(16):3076-3091. Pantarelli C, Pan D, Chetwynd S, Stark AK, Hornigold K, Machin P, Crossland L, Cleary SJ, Baker MJ, Hampson E, Mandel A, Segonds-Pichon A, Walker R, van 't Veer C, Riffo-Vasquez Y, Okkenhaug K, Pitchford S, Welch HCE. PMID: 34402884; PMCID: PMC8405187.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    12. Red Blood Cells Elicit Platelet-Dependent Neutrophil Recruitment Into Lung Airspaces. Shock. 2021 08 01; 56(2):278-286. Arnold S, Shah SA, Cleary SJ, O'Shaughnessy BG, Amison RT, Arkless K, Page CP, Pitchford SC. PMID: 33306620.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    13. Platelets Independently Recruit into Asthmatic Lungs and Models of Allergic Inflammation via CCR3. Am J Respir Cell Mol Biol. 2021 05; 64(5):557-568. Shah SA, Kanabar V, Riffo-Vasquez Y, Mohamed Z, Cleary SJ, Corrigan C, James AL, Elliot JG, Shute JK, Page CP, Pitchford SC. PMID: 33556295; PMCID: PMC8086046.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    14. Chewing the fat on TRALI. Blood. 2021 02 04; 137(5):586-587. Cleary SJ, Looney MR. PMID: 33538806; PMCID: PMC8667048.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    15. Natural killer cells activated through NKG2D mediate lung ischemia-reperfusion injury. J Clin Invest. 2021 02 01; 131(3). Calabrese DR, Aminian E, Mallavia B, Liu F, Cleary SJ, Aguilar OA, Wang P, Singer JP, Hays SR, Golden JA, Kukreja J, Dugger D, Nakamura M, Lanier LL, Looney MR, Greenland JR. PMID: 33290276; PMCID: PMC7852842.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    16. β2M Signals Monocytes Through Non-Canonical TGFβ Receptor Signal Transduction. Circ Res. 2021 03 05; 128(5):655-669. Hilt ZT, Maurya P, Tesoro L, Pariser DN, Ture SK, Cleary SJ, Looney MR, McGrath KE, Morrell CN. PMID: 33508948; PMCID: PMC8319031.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    17. Global absence and targeting of protective immune states in severe COVID-19. Nature. 2021 03; 591(7848):124-130. Combes AJ, Courau T, Kuhn NF, Hu KH, Ray A, Chen WS, Chew NW, Cleary SJ, Kushnoor D, Reeder GC, Shen A, Tsui J, Hiam-Galvez KJ, Muñoz-Sandoval P, Zhu WS, Lee DS, Sun Y, You R, Magnen M, Rodriguez L, Im KW, Serwas NK, Leligdowicz A, Zamecnik CR, Loudermilk RP, Wilson MR, Ye CJ, Fragiadakis GK, Looney MR, Chan V, Ward A, Carrillo S, UCSF COMET Consortium, Matthay M, Erle DJ, Woodruff PG, Langelier C, Kangelaris K, Hendrickson CM, Calfee C, Rao AA, Krummel MF. PMID: 33494096; PMCID: PMC8567458.
      View in: PubMed   Mentions: 127     Fields:    Translation:HumansCells
    18. Lung megakaryocytes are immune modulatory cells. J Clin Invest. 2021 01 04; 131(1). Pariser DN, Hilt ZT, Ture SK, Blick-Nitko SK, Looney MR, Cleary SJ, Roman-Pagan E, Saunders J, Georas SN, Veazey J, Madere F, Santos LT, Arne A, Huynh NP, Livada AC, Guerrero-Martin SM, Lyons C, Metcalf-Pate KA, McGrath KE, Palis J, Morrell CN. PMID: 33079726; PMCID: PMC7773372.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    19. Complement activation on endothelium initiates antibody-mediated acute lung injury. J Clin Invest. 2020 11 02; 130(11):5909-5923. Cleary SJ, Kwaan N, Tian JJ, Calabrese DR, Mallavia B, Magnen M, Greenland JR, Urisman A, Singer JP, Hays SR, Kukreja J, Hay AM, Howie HL, Toy P, Lowell CA, Morrell CN, Zimring JC, Looney MR. PMID: 32730229; PMCID: PMC7598054.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    20. Update on animal models for COVID-19 research. Br J Pharmacol. 2020 12; 177(24):5679-5681. Cleary SJ, Magnen M, Looney MR, Page CP. PMID: 33140409; PMCID: PMC7707085.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    21. Global Absence and Targeting of Protective Immune States in Severe COVID-19. bioRxiv. 2020 Oct 29. Combes AJ, Courau T, Kuhn NF, Hu KH, Ray A, Chen WS, Cleary SJ, Chew NW, Kushnoor D, Reeder GC, Shen A, Tsui J, Hiam-Galvez KJ, Muñoz-Sandoval P, Zhu WS, Lee DS, Sun Y, You R, Magnen M, Rodriguez L, Leligdowicz A, Zamecnik CR, Loudermilk RP, Wilson MR, Ye CJ, Fragiadakis GK, Looney MR, Chan V, Ward A, Carrillo S, Matthay M, Erle DJ, Woodruff PG, Langelier C, Kangelaris K, Hendrickson CM, Calfee C, Rao AA, Krummel MF. PMID: 33140050; PMCID: PMC7605559.
      View in: PubMed   Mentions:
    22. Animal models of mechanisms of SARS-CoV-2 infection and COVID-19 pathology. Br J Pharmacol. 2020 11; 177(21):4851-4865. Cleary SJ, Pitchford SC, Amison RT, Carrington R, Robaina Cabrera CL, Magnen M, Looney MR, Gray E, Page CP. PMID: 32462701; PMCID: PMC7283621.
      View in: PubMed   Mentions: 107     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    23. Mitochondrial DNA Stimulates TLR9-Dependent Neutrophil Extracellular Trap Formation in Primary Graft Dysfunction. Am J Respir Cell Mol Biol. 2020 03; 62(3):364-372. Mallavia B, Liu F, Lefrançais E, Cleary SJ, Kwaan N, Tian JJ, Magnen M, Sayah DM, Soong A, Chen J, Saggar R, Shino MY, Ross DJ, Derhovanessian A, Lynch JP, Ardehali A, Weigt SS, Belperio JA, Hays SR, Golden JA, Leard LE, Shah RJ, Kleinhenz ME, Venado A, Kukreja J, Singer JP, Looney MR. PMID: 31647878; PMCID: PMC7055700.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    24. Radiolabelling and immunohistochemistry reveal platelet recruitment into lungs and platelet migration into airspaces following LPS inhalation in mice. J Pharmacol Toxicol Methods. 2020 Mar - Apr; 102:106660. Cleary SJ, Rauzi F, Smyth E, Correia A, Hobbs C, Emerson M, Page CP, Pitchford SC. PMID: 31838234.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    25. LPS-induced Lung Platelet Recruitment Occurs Independently from Neutrophils, PSGL-1, and P-Selectin. Am J Respir Cell Mol Biol. 2019 08; 61(2):232-243. Cleary SJ, Hobbs C, Amison RT, Arnold S, O'Shaughnessy BG, Lefrançais E, Mallavia B, Looney MR, Page CP, Pitchford SC. PMID: 30768917; PMCID: PMC6670039.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    26. Pharmacological strategies for targeting platelet activation in asthma. Curr Opin Pharmacol. 2019 06; 46:55-64. Pitchford S, Cleary S, Arkless K, Amison R. PMID: 31026626.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    27. Gustav Born: pioneer in imaging platelet and leukocyte biology. Platelets. 2018 Dec; 29(8):766-770. Cleary SJ, Page CP. PMID: 30411649.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    28. Sensory nerves mediate spontaneous behaviors in addition to inflammation in a murine model of psoriasis. FASEB J. 2019 02; 33(2):1578-1594. Kodji X, Arkless KL, Kee Z, Cleary SJ, Aubdool AA, Evans E, Caton P, Pitchford SC, Brain SD. PMID: 30204499; PMCID: PMC6338626.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    29. Platelets Play a Central Role in Sensitization to Allergen. Am J Respir Cell Mol Biol. 2018 07; 59(1):96-103. Amison RT, Cleary SJ, Riffo-Vasquez Y, Bajwa M, Page CP, Pitchford SC. PMID: 29365287.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCellsPHPublic Health
    30. Platelet Depletion Impairs Host Defense to Pulmonary Infection with Pseudomonas aeruginosa in Mice. Am J Respir Cell Mol Biol. 2018 03; 58(3):331-340. Amison RT, O'Shaughnessy BG, Arnold S, Cleary SJ, Nandi M, Pitchford SC, Bragonzi A, Page CP. PMID: 28957635.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    31. Lipopolysaccharide (LPS) induced pulmonary neutrophil recruitment and platelet activation is mediated via the P2Y1 and P2Y14 receptors in mice. Pulm Pharmacol Ther. 2017 08; 45:62-68. Amison RT, Arnold S, O'Shaughnessy BG, Cleary SJ, Ofoedu J, Idzko M, Page CP, Pitchford SC. PMID: 28487256.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    32. The application of local hypobaric pressure - A novel means to enhance macromolecule entry into the skin. J Control Release. 2016 Mar 28; 226:66-76. Inacio R, Poland S, Cai XJ, Cleary SJ, Ameer-Beg S, Keeble J, Jones SA. PMID: 26829103; PMCID: PMC4819566.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    33. P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation. Blood. 2015 Feb 12; 125(7):1146-58. Pan D, Amison RT, Riffo-Vasquez Y, Spina D, Cleary SJ, Wakelam MJ, Page CP, Pitchford SC, Welch HC. PMID: 25538043; PMCID: PMC4326774.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
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