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Sonia Bonifacio, MD

TitleAssistant Professor
SchoolUCSF School of Medicine
DepartmentPediatrics
Address533 Parnassus Ave, UC Hall
San Francisco CA 94143
Phone415-476-1888
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoM.D.2003 Medicine

    Collapse Research 
    Collapse Research Activities and Funding
    Early Biomarkers in Neonatal Brain Injury
    NIH/NINDS K23NS082500Sep 1, 2013 - Aug 31, 2018
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Glass HC, Shellhaas RA, Tsuchida TN, Chang T, Wusthoff CJ, Chu CJ, Cilio MR, Bonifacio SL, Massey SL, Abend NS, Soul JS. Seizures in Preterm Neonates: A Multicenter Observational Cohort Study. Pediatr Neurol. 2017 Jul; 72:19-24. PMID: 28558955.
      View in: PubMed
    2. Van Meurs KP, Bonifacio S. Brain-focused care in the neonatal intensive care unit: the time has come. J Pediatr (Rio J). 2017 Mar 28. PMID: 28359015.
      View in: PubMed
    3. Lemmon ME, Boss RD, Bonifacio SL, Foster-Barber A, Barkovich AJ, Glass HC. Characterization of Death in Neonatal Encephalopathy in the Hypothermia Era. J Child Neurol. 2017 Mar; 32(4):360-365. PMID: 28193115.
      View in: PubMed
    4. Shellhaas R, Chang T, Wusthoff C, Soul J, Massey S, Chu C, Cilio MR, Bonifacio S, Abend N, Tsuchida T, Glass H. Treatment Duration After Acute Symptomatic Seizures in Neonates: A Multicenter Cohort Study. J Pediatr. 2017 02; 181:298-301.e1. PMID: 27829512.
      View in: PubMed
    5. Frymoyer A, Bonifacio SL, Drover DR, Su F, Wustoff CJ, Van Meurs KP. Decreased Morphine Clearance in Neonates With Hypoxic Ischemic Encephalopathy Receiving Hypothermia. J Clin Pharmacol. 2017 Jan; 57(1):64-76. PMID: 27225747.
      View in: PubMed
    6. Wu YW, Mathur AM, Chang T, McKinstry RC, Mulkey SB, Mayock DE, Van Meurs KP, Rogers EE, Gonzalez FF, Comstock BA, Juul SE, Msall ME, Bonifacio SL, Glass HC, Massaro AN, Dong L, Tan KW, Heagerty PJ, Ballard RA. High-Dose Erythropoietin and Hypothermia for Hypoxic-Ischemic Encephalopathy: A Phase II Trial. Pediatrics. 2016 Jun; 137(6). PMID: 27244862.
      View in: PubMed
    7. Glass HC, Shellhaas RA, Wusthoff CJ, Chang T, Abend NS, Chu CJ, Cilio MR, Glidden DV, Bonifacio SL, Massey S, Tsuchida TN, Silverstein FS, Soul JS. Contemporary Profile of Seizures in Neonates: A Prospective Cohort Study. J Pediatr. 2016 Jul; 174:98-103.e1. PMID: 27106855; PMCID: PMC4925241 [Available on 07/01/17].
    8. Peloquin S, Carley A, Bonifacio SL, Glass HC. The Neurointensive Care Nursery and Evolving Roles for Nursing. Neonatal Netw. 2016; 35(2):87-94. PMID: 27052983.
      View in: PubMed
    9. Wietstock SO, Bonifacio SL, Sullivan JE, Nash KB, Glass HC. Continuous Video Electroencephalographic (EEG) Monitoring for Electrographic Seizure Diagnosis in Neonates: A Single-Center Study. J Child Neurol. 2016 Mar; 31(3):328-32. PMID: 26129976; PMCID: PMC4696927 [Available on 03/01/17].
    10. Mrelashvili A, Bonifacio SL, Rogers EE, Shimotake TK, Glass HC. Outcome After Therapeutic Hypothermia in Term Neonates With Encephalopathy and a Syndromic Diagnosis. J Child Neurol. 2015 Oct; 30(11):1453-8. PMID: 25762585; PMCID: PMC4567555 [Available on 10/01/16].
    11. Bonifacio SL, deVries LS, Groenendaal F. Impact of hypothermia on predictors of poor outcome: how do we decide to redirect care? Semin Fetal Neonatal Med. 2015 Apr; 20(2):122-7. PMID: 25577654; PMCID: PMC4375009.
    12. Wietstock SO, Bonifacio SL, McCulloch CE, Kuzniewicz MW, Glass HC. Neonatal Neurocritical Care Service Is Associated With Decreased Administration of Seizure Medication. J Child Neurol. 2015 Aug; 30(9):1135-41. PMID: 25380602; PMCID: PMC4424192.
    13. Rothman SM, Glass HC, Chang T, Sullivan JE, Bonifacio SL, Shellhaas RA. Risk factors for EEG seizures in neonates treated with hypothermia: a multicenter cohort study. Neurology. 2014 Nov 04; 83(19):1773-4. PMID: 25367061.
      View in: PubMed
    14. Glass HC, Rogers EE, Peloquin S, Bonifacio SL. Interdisciplinary approach to neurocritical care in the intensive care nursery. Semin Pediatr Neurol. 2014 Dec; 21(4):241-7. PMID: 25727505.
      View in: PubMed
    15. Gano D, Andersen SK, Partridge JC, Bonifacio SL, Xu D, Glidden DV, Ferriero DM, Barkovich AJ, Glass HC. Diminished white matter injury over time in a cohort of premature newborns. J Pediatr. 2015 Jan; 166(1):39-43. PMID: 25311709; PMCID: PMC4274204.
    16. Sampson MR, Frymoyer A, Rattray B, Cotten CM, Smith PB, Capparelli E, Bonifacio SL, Cohen-Wolkowiez M. Predictive performance of a gentamicin population pharmacokinetic model in neonates receiving full-body hypothermia. Ther Drug Monit. 2014 Oct; 36(5):584-9. PMID: 25225917; PMCID: PMC4166612.
    17. Rogers EE, Bonifacio SL, Glass HC, Juul SE, Chang T, Mayock DE, Durand DJ, Song D, Barkovich AJ, Ballard RA, Wu YW. Erythropoietin and hypothermia for hypoxic-ischemic encephalopathy. Pediatr Neurol. 2014 Nov; 51(5):657-62. PMID: 25439577; PMCID: PMC4402201.
    18. Jenster M, Bonifacio SL, Ruel T, Rogers EE, Tam EW, Partridge JC, Barkovich AJ, Ferriero DM, Glass HC. Maternal or neonatal infection: association with neonatal encephalopathy outcomes. Pediatr Res. 2014 Jul; 76(1):93-9. PMID: 24713817; PMCID: PMC4062582.
    19. Glass HC, Wusthoff CJ, Shellhaas RA, Tsuchida TN, Bonifacio SL, Cordeiro M, Sullivan J, Abend NS, Chang T. Risk factors for EEG seizures in neonates treated with hypothermia: a multicenter cohort study. Neurology. 2014 Apr 08; 82(14):1239-44. PMID: 24610326; PMCID: PMC4001204.
    20. Gano D, Orbach SA, Bonifacio S, Glass HC. Neonatal seizures and therapeutic hypothermia for hypoxic-ischemic encephalopathy. Mol Cell Epilepsy. 2014; 1(3). PMID: 26052538.
      View in: PubMed
    21. Ferriero DM, Bonifacio SL. The search continues for the elusive biomarkers of neonatal brain injury. J Pediatr. 2014 Mar; 164(3):438-40. PMID: 24388328.
      View in: PubMed
    22. Orbach SA, Bonifacio SL, Kuzniewicz MW, Glass HC. Lower incidence of seizure among neonates treated with therapeutic hypothermia. J Child Neurol. 2014 Nov; 29(11):1502-7. PMID: 24334344; PMCID: PMC4053513.
    23. Frymoyer A, Lee S, Bonifacio SL, Meng L, Lucas SS, Guglielmo BJ, Sun Y, Verotta D. Every 36-h gentamicin dosing in neonates with hypoxic-ischemic encephalopathy receiving hypothermia. J Perinatol. 2013 Oct; 33(10):778-82. PMID: 23702622; PMCID: PMC3762884.
    24. Frymoyer A, Meng L, Bonifacio SL, Verotta D, Guglielmo BJ. Gentamicin pharmacokinetics and dosing in neonates with hypoxic ischemic encephalopathy receiving hypothermia. Pharmacotherapy. 2013 Jul; 33(7):718-26. PMID: 23553582; PMCID: PMC3700641.
    25. Wu YW, Bauer LA, Ballard RA, Ferriero DM, Glidden DV, Mayock DE, Chang T, Durand DJ, Song D, Bonifacio SL, Gonzalez FF, Glass HC, Juul SE. Erythropoietin for neuroprotection in neonatal encephalopathy: safety and pharmacokinetics. Pediatrics. 2012 Oct; 130(4):683-91. PMID: 23008465; PMCID: PMC3457622.
    26. Bonifacio SL, Saporta A, Glass HC, Lee P, Glidden DV, Ferriero DM, Barkovich AJ, Xu D. Therapeutic hypothermia for neonatal encephalopathy results in improved microstructure and metabolism in the deep gray nuclei. AJNR Am J Neuroradiol. 2012 Dec; 33(11):2050-5. PMID: 22595900; PMCID: PMC3473161.
    27. Tymofiyeva O, Hess CP, Ziv E, Tian N, Bonifacio SL, McQuillen PS, Ferriero DM, Barkovich AJ, Xu D. Towards the "baby connectome": mapping the structural connectivity of the newborn brain. PLoS One. 2012; 7(2):e31029. PMID: 22347423; PMCID: PMC3274551.
    28. Tam EW, Haeusslein LA, Bonifacio SL, Glass HC, Rogers EE, Jeremy RJ, Barkovich AJ, Ferriero DM. Hypoglycemia is associated with increased risk for brain injury and adverse neurodevelopmental outcome in neonates at risk for encephalopathy. J Pediatr. 2012 Jul; 161(1):88-93. PMID: 22306045; PMCID: PMC3346850.
    29. Glass HC, Kan J, Bonifacio SL, Ferriero DM. Neonatal seizures: treatment practices among term and preterm infants. Pediatr Neurol. 2012 Feb; 46(2):111-5. PMID: 22264706; PMCID: PMC3266555.
    30. Glass HC, Bonifacio SL, Shimotake T, Ferriero DM. Neurocritical care for neonates. Curr Treat Options Neurol. 2011 Dec; 13(6):574-89. PMID: 21874296.
      View in: PubMed
    31. Glass HC, Hong KJ, Rogers EE, Jeremy RJ, Bonifacio SL, Sullivan JE, Barkovich AJ, Ferriero DM. Risk factors for epilepsy in children with neonatal encephalopathy. Pediatr Res. 2011 Nov; 70(5):535-40. PMID: 21796017; PMCID: PMC3189270.
    32. Glass HC, Nash KB, Bonifacio SL, Barkovich AJ, Ferriero DM, Sullivan JE, Cilio MR. Seizures and magnetic resonance imaging-detected brain injury in newborns cooled for hypoxic-ischemic encephalopathy. J Pediatr. 2011 Nov; 159(5):731-735.e1. PMID: 21839470; PMCID: PMC3193544.
    33. Bonifacio SL, Glass HC, Peloquin S, Ferriero DM. A new neurological focus in neonatal intensive care. Nat Rev Neurol. 2011 Aug 02; 7(9):485-94. PMID: 21808297.
      View in: PubMed
    34. Harbert MJ, Tam EW, Glass HC, Bonifacio SL, Haeusslein LA, Barkovich AJ, Jeremy RJ, Rogers EE, Glidden DV, Ferriero DM. Hypothermia is correlated with seizure absence in perinatal stroke. J Child Neurol. 2011 Sep; 26(9):1126-30. PMID: 21700899; PMCID: PMC3594994.
    35. Nash KB, Bonifacio SL, Glass HC, Sullivan JE, Barkovich AJ, Ferriero DM, Cilio MR. Video-EEG monitoring in newborns with hypoxic-ischemic encephalopathy treated with hypothermia. Neurology. 2011 Feb 08; 76(6):556-62. PMID: 21300971; PMCID: PMC3053178.
    36. Xu D, Bonifacio SL, Charlton NN, P Vaughan C, Lu Y, Ferriero DM, Vigneron DB, Barkovich AJ. MR spectroscopy of normative premature newborns. J Magn Reson Imaging. 2011 Feb; 33(2):306-11. PMID: 21274971; PMCID: PMC3391540.
    37. Bonifacio SL, Glass HC, Chau V, Berman JI, Xu D, Brant R, Barkovich AJ, Poskitt KJ, Miller SP, Ferriero DM. Extreme premature birth is not associated with impaired development of brain microstructure. J Pediatr. 2010 Nov; 157(5):726-32.e1. PMID: 20598316; PMCID: PMC2957506.
    38. Bonifacio SL, Glass HC, Vanderpluym J, Agrawal AT, Xu D, Barkovich AJ, Ferriero DM. Perinatal events and early magnetic resonance imaging in therapeutic hypothermia. J Pediatr. 2011 Mar; 158(3):360-5. PMID: 20965514; PMCID: PMC3035732.
    39. Glass HC, Bonifacio SL, Peloquin S, Shimotake T, Sehring S, Sun Y, Sullivan J, Rogers E, Barkovich AJ, Rowitch D, Ferriero DM. Neurocritical care for neonates. Neurocrit Care. 2010 Jun; 12(3):421-9. PMID: 20066514; PMCID: PMC2881702.
    40. Glass HC, Bonifacio SL, Sullivan J, Rogers E, Ferriero DM, Goldstein R, Barkovich AJ. Magnetic resonance imaging and ultrasound injury in preterm infants with seizures. J Child Neurol. 2009 Sep; 24(9):1105-11. PMID: 19745086; PMCID: PMC3014150.
    41. Glass HC, Bonifacio SL, Chau V, Glidden D, Poskitt K, Barkovich AJ, Ferriero DM, Miller SP. Recurrent postnatal infections are associated with progressive white matter injury in premature infants. Pediatrics. 2008 Aug; 122(2):299-305. PMID: 18676547.
      View in: PubMed
    42. Miller SP, Wu YW, Lee J, Lammer EJ, Iovannisci DM, Glidden DV, Bonifacio SL, Collins A, Shaw GM, Barkovich AJ, Ferriero DM. Candidate gene polymorphisms do not differ between newborns with stroke and normal controls. Stroke. 2006 Nov; 37(11):2678-83. PMID: 17008620.
      View in: PubMed
    43. Bonifacio SL, Kitterman JA, Ursell PC. Pseudomonas pneumonia in infants: an autopsy study. Hum Pathol. 2003 Sep; 34(9):929-38. PMID: 14562290.
      View in: PubMed
    44. Bortolini U, Zmarich C, Fior R, Bonifacio S. Word-initial voicing in the productions of stops in normal and preterm Italian infants. Int J Pediatr Otorhinolaryngol. 1995 Mar; 31(2-3):191-206. PMID: 7782177.
      View in: PubMed
    45. Bortolini U, Bonifacio S, Fior R, Zmarich C. [Developmental aspects of language articulation in preterm and small fullterm infants]. Minerva Pediatr. 1992 Jan-Feb; 44(1-2):27-32. PMID: 1552873.
      View in: PubMed
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