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Sophie Dumont, PhD

TitleAssistant Professor
SchoolUCSF School of Dentistry
DepartmentCell and Tissue Biology
Address513 Parnassus Ave
San Francisco CA 94143
Phone415-502-1229
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    Collapse Biography 
    Collapse Awards and Honors
    2016 - 2021NSF CAREER Award
    2016Margaret Oakley Dayhoff Award of the Biophysical Society
    2015 - 2020NIH New Innovator Award
    2013 - 2018Rita Allen Foundation and Milton E. Cassel Scholar
    2013 - 2016Searle Scholar
    2013 - 2015Sloan Research Fellow
    2013 - 2015Kimmel Cancer Foundation Scholar
    2006 - 2009Junior Fellow, Harvard Society of Fellows
    2006Weintraub Graduate Student Award
    2006Alan Bearden Outstanding Graduate Research Award, UC Berkeley
    1999Rhodes Scholarship
    1999Allen G. Shenstone Prize in Physics, Princeton University

    Collapse Research 
    Collapse Research Activities and Funding
    Rewiring cellular architecture to probe mechanical signal processing at kinetochores
    NIH/NIGMS DP2GM119177Sep 30, 2015 - May 31, 2020
    Role: Principal Investigator
    Spindle forces for chromosome movement
    NIH/NIGMS R00GM094335Sep 1, 2010 - Jul 31, 2015
    Role: Principal Investigator
    Force generation and detection in the spindle: the case of the kinetochore
    NIH/NIGMS K99GM094335Sep 1, 2010 - May 31, 2012
    Role: Principal Investigator

    Collapse ORNG Applications 
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    Collapse In The News
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Hueschen CL, Long AF, Dumont S. Kinesin-5: A Team Is Just the Sum of Its Parts. Dev Cell. 2015 Sep 28; 34(6):609-10. PMID: 26418291.
      View in: PubMed
    2. Udy DB, Voorhies M, Chan PP, Lowe TM, Dumont S. Draft De Novo Transcriptome of the Rat Kangaroo Potorous tridactylus as a Tool for Cell Biology. PLoS One. 2015; 10(8):e0134738. PMID: 26252667; PMCID: PMC4529305.
    3. Dumont S, Prakash M. Emergent mechanics of biological structures. Mol Biol Cell. 2014 Nov 5; 25(22):3461-5. PMID: 25368421; PMCID: PMC4230603.
    4. Elting MW, Hueschen CL, Udy DB, Dumont S. Force on spindle microtubule minus ends moves chromosomes. J Cell Biol. 2014 Jul 21; 206(2):245-56. PMID: 25023517; PMCID: PMC4107791.
    5. Dumont S. Spindle size: small droplets and a big step forward. Curr Biol. 2014 Feb 3; 24(3):R116-8. PMID: 24502785.
      View in: PubMed
    6. Kuhn J, Dumont S. Imaging and physically probing kinetochores in live dividing cells. Methods Cell Biol. 2014; 123:467-87. PMID: 24974043; PMCID: PMC4441532.
    7. Dumont S, Salmon ED, Mitchison TJ. Deformations within moving kinetochores reveal different sites of active and passive force generation. Science. 2012 Jul 20; 337(6092):355-8. PMID: 22722252; PMCID: PMC3672420.
    8. Dumont S, Mitchison TJ. Comprehensive Biophysics. Mechanical Forces in Mitosis. 2012; 298-320.
    9. Dumont S. Chromosome segregation: spindle mechanics come to life. Curr Biol. 2011 Sep 27; 21(18):R688-90. PMID: 21959154.
      View in: PubMed
    10. Dumont S, Mitchison TJ. Force and length in the mitotic spindle. Curr Biol. 2009 Sep 15; 19(17):R749-61. PMID: 19906577; PMCID: PMC2791830.
    11. Dumont S, Mitchison TJ. Compression regulates mitotic spindle length by a mechanochemical switch at the poles. Curr Biol. 2009 Jul 14; 19(13):1086-95. PMID: 19540117; PMCID: PMC2722833.
    12. Wühr M, Dumont S, Groen AC, Needleman DJ, Mitchison TJ. How does a millimeter-sized cell find its center? Cell Cycle. 2009 Apr 15; 8(8):1115-21. PMID: 19282671; PMCID: PMC2880816.
    13. Wühr M, Chen Y, Dumont S, Groen AC, Needleman DJ, Salic A, Mitchison TJ. Evidence for an upper limit to mitotic spindle length. Curr Biol. 2008 Aug 26; 18(16):1256-61. PMID: 18718761; PMCID: PMC2561182.
    14. Cheng W, Dumont S, Tinoco I, Bustamante C. NS3 helicase actively separates RNA strands and senses sequence barriers ahead of the opening fork. Proc Natl Acad Sci U S A. 2007 Aug 28; 104(35):13954-9. PMID: 17709749; PMCID: PMC1955789.
    15. Dumont S, Cheng W, Serebrov V, Beran RK, Tinoco I, Pyle AM, Bustamante C. RNA translocation and unwinding mechanism of HCV NS3 helicase and its coordination by ATP. Nature. 2006 Jan 5; 439(7072):105-8. PMID: 16397502; PMCID: PMC1560093.
    16. Onoa B, Dumont S, Liphardt J, Smith SB, Tinoco I, Bustamante C. Identifying kinetic barriers to mechanical unfolding of the T. thermophila ribozyme. Science. 2003 Mar 21; 299(5614):1892-5. PMID: 12649482; PMCID: PMC1503549.
    17. Liphardt J, Dumont S, Smith SB, Tinoco I, Bustamante C. Equilibrium information from nonequilibrium measurements in an experimental test of Jarzynski's equality. Science. 2002 Jun 7; 296(5574):1832-5. PMID: 12052949.
      View in: PubMed
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