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    Synthia Mellon, PhD

    TitleProfessor
    SchoolUCSF School of Medicine
    DepartmentOb/Gyn, Reproductive Sciences
    Address513 Parnassus Ave
    San Francisco CA 94143
    Phone415-476-5329
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Jin RO, Mason S, Mellon SH, Epel ES, Reus VI, Mahan L, Rosser RL, Hough CM, Burke HM, Mueller SG, Wolkowitz OM. Cortisol/DHEA ratio and hippocampal volume: A pilot study in major depression and healthy controls. Psychoneuroendocrinology. 2016 Oct; 72:139-46. PMID: 27428086.
        View in: PubMed
      2. Mellon SH, Wolkowitz OM, Schonemann MD, Epel ES, Rosser R, Burke HB, Mahan L, Reus VI, Stamatiou D, Liew CC, Cole SW. Alterations in leukocyte transcriptional control pathway activity associated with major depressive disorder and antidepressant treatment. Transl Psychiatry. 2016; 6:e821. PMID: 27219347.
        View in: PubMed
      3. Bersani FS, Wolkowitz OM, Milush JM, Sinclair E, Eppling L, Aschbacher K, Lindqvist D, Yehuda R, Flory J, Bierer LM, Matokine I, Abu-Amara D, Reus VI, Coy M, Hough CM, Marmar CR, Mellon SH. A population of atypical CD56(-)CD16(+) natural killer cells is expanded in PTSD and is associated with symptom severity. Brain Behav Immun. 2016 Aug; 56:264-70. PMID: 27025668.
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      4. Bersani FS, Lindqvist D, Mellon SH, Epel ES, Yehuda R, Flory J, Henn-Hasse C, Bierer LM, Makotkine I, Abu-Amara D, Coy M, Reus VI, Lin J, Blackburn EH, Marmar C, Wolkowitz OM. Association of dimensional psychological health measures with telomere length in male war veterans. J Affect Disord. 2016 Jan 15; 190:537-42. PMID: 26571103.
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      5. Bersani FS, Wolkowitz OM, Lindqvist D, Yehuda R, Flory J, Bierer LM, Makotine I, Abu-Amara D, Coy M, Reus VI, Epel ES, Marmar C, Mellon SH. Global arginine bioavailability, a marker of nitric oxide synthetic capacity, is decreased in PTSD and correlated with symptom severity and markers of inflammation. Brain Behav Immun. 2016 Feb; 52:153-60. PMID: 26515034.
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      6. Mueller SG, Ng P, Neylan T, Mackin S, Wolkowitz O, Mellon S, Yan X, Flory J, Yehuda R, Marmar CR, Weiner MW. Evidence for disrupted gray matter structural connectivity in posttraumatic stress disorder. Psychiatry Res. 2015 Nov 30; 234(2):194-201. PMID: 26419357.
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      7. Fair B, Mellon SH, Epel ES, Révész D, Verhoeven JE, Penninx BW, Reus VI, Mahan L, Hough C, Rosser R, Burke HM, Lin J, Blackburn EH, Wolkowitz OM. Telomere length is inversely correlated with urinary stress hormone levels in healthy controls but not in un-medicated depressed individuals - Preliminary findings. Psychoneuroendocrinology. 2015 Nov; 61:61. PMID: 26383442.
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      8. Bersani FS, Lindqvist D, Mellon SH, Penninx BW, Verhoeven JE, Révész D, Reus VI, Wolkowitz OM. Telomerase activation as a possible mechanism of action for psychopharmacological interventions. Drug Discov Today. 2015 Nov; 20(11):1305-9. PMID: 26166813.
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      9. Bersani FS, Morley C, Lindqvist D, Epel ES, Picard M, Yehuda R, Flory J, Bierer LM, Makotkine I, Abu-Amara D, Coy M, Reus VI, Lin J, Blackburn EH, Marmar C, Wolkowitz OM, Mellon SH. Mitochondrial DNA copy number is reduced in male combat veterans with PTSD. Prog Neuropsychopharmacol Biol Psychiatry. 2016 Jan 4; 64:10-7. PMID: 26120081.
        View in: PubMed
      10. Lindqvist D, Epel ES, Mellon SH, Penninx BW, Révész D, Verhoeven JE, Reus VI, Lin J, Mahan L, Hough CM, Rosser R, Bersani FS, Blackburn EH, Wolkowitz OM. Psychiatric disorders and leukocyte telomere length: Underlying mechanisms linking mental illness with cellular aging. Neurosci Biobehav Rev. 2015 Aug; 55:333-64. PMID: 25999120; PMCID: PMC4501875 [Available on 08/01/16].
      11. Wolkowitz OM, Mellon SH, Lindqvist D, Epel ES, Blackburn EH, Lin J, Reus VI, Burke H, Rosser R, Mahan L, Mackin S, Yang T, Weiner M, Mueller S. PBMC telomerase activity, but not leukocyte telomere length, correlates with hippocampal volume in major depression. Psychiatry Res. 2015 Apr 30; 232(1):58-64. PMID: 25773002; PMCID: PMC4404215 [Available on 04/30/16].
      12. Lindqvist D, Mueller S, Mellon SH, Su Y, Epel ES, Reus VI, Rosser R, Mahan L, Mackin RS, Yang TT, Wolkowitz OM. Peripheral antioxidant markers are associated with total hippocampal and CA3/dentate gyrus volume in MDD and healthy controls-preliminary findings. Psychiatry Res. 2014 Dec 30; 224(3):168-74. PMID: 25266915; PMCID: PMC4254356 [Available on 12/30/15].
      13. Chen SH, Epel ES, Mellon SH, Lin J, Reus VI, Rosser R, Kupferman E, Burke H, Mahan L, Blackburn EH, Wolkowitz OM. Adverse childhood experiences and leukocyte telomere maintenance in depressed and healthy adults. J Affect Disord. 2014 Dec; 169:86-90. PMID: 25173430; PMCID: PMC4172492 [Available on 12/01/15].
      14. Lindqvist D, Wolkowitz OM, Mellon S, Yehuda R, Flory JD, Henn-Haase C, Bierer LM, Abu-Amara D, Coy M, Neylan TC, Makotkine I, Reus VI, Yan X, Taylor NM, Marmar CR, Dhabhar FS. Proinflammatory milieu in combat-related PTSD is independent of depression and early life stress. Brain Behav Immun. 2014 Nov; 42:81-8. PMID: 24929195.
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      15. Rawdin BJ, Mellon SH, Dhabhar FS, Epel ES, Puterman E, Su Y, Burke HM, Reus VI, Rosser R, Hamilton SP, Nelson JC, Wolkowitz OM. Dysregulated relationship of inflammation and oxidative stress in major depression. Brain Behav Immun. 2013 Jul; 31:143-52. PMID: 23201587; PMCID: PMC3669232.
      16. Lee S, Leach MK, Redmond SA, Chong SY, Mellon SH, Tuck SJ, Feng ZQ, Corey JM, Chan JR. A culture system to study oligodendrocyte myelination processes using engineered nanofibers. Nat Methods. 2012 Sep; 9(9):917-22. PMID: 22796663; PMCID: PMC3433633.
      17. Schonemann MD, Muench MO, Tee MK, Miller WL, Mellon SH. Expression of P450c17 in the human fetal nervous system. Endocrinology. 2012 May; 153(5):2494-505. PMID: 22434081; PMCID: PMC3339640.
      18. Jiang L, Shen F, Degos V, Schonemann M, Pleasure SJ, Mellon SH, Young WL, Su H. Oligogenesis and oligodendrocyte progenitor maturation vary in different brain regions and partially correlate with local angiogenesis after ischemic stroke. Transl Stroke Res. 2011 Sep; 2(3):366-75. PMID: 22022343; PMCID: PMC3196661.
      19. Wolkowitz OM, Wolf J, Shelly W, Rosser R, Burke HM, Lerner GK, Reus VI, Nelson JC, Epel ES, Mellon SH. Serum BDNF levels before treatment predict SSRI response in depression. Prog Neuropsychopharmacol Biol Psychiatry. 2011 Aug 15; 35(7):1623-30. PMID: 21749907; PMCID: PMC3159044.
      20. Wolkowitz OM, Mellon SH, Epel ES, Lin J, Dhabhar FS, Su Y, Reus VI, Rosser R, Burke HM, Kupferman E, Compagnone M, Nelson JC, Blackburn EH. Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress--preliminary findings. PLoS One. 2011; 6(3):e17837. PMID: 21448457; PMCID: PMC3063175.
      21. Wolkowitz OM, Mellon SH, Epel ES, Lin J, Reus VI, Rosser R, Burke H, Compagnone M, Nelson JC, Dhabhar FS, Blackburn EH. Resting leukocyte telomerase activity is elevated in major depression and predicts treatment response. Mol Psychiatry. 2012 Feb; 17(2):164-72. PMID: 21242992; PMCID: PMC3130817.
      22. Wolkowitz OM, Reus VI, Mellon SH. Of sound mind and body: depression, disease, and accelerated aging. Dialogues Clin Neurosci. 2011; 13(1):25-39. PMID: 21485744; PMCID: PMC3181963.
      23. Zhang L, Blackman BE, Schonemann MD, Zogovic-Kapsalis T, Pan X, Tagliaferri M, Harris HA, Cohen I, Pera RA, Mellon SH, Weiner RI, Leitman DC. Estrogen receptor beta-selective agonists stimulate calcium oscillations in human and mouse embryonic stem cell-derived neurons. PLoS One. 2010; 5(7):e11791. PMID: 20668547; PMCID: PMC2910705.
      24. Berger W, Mehra A, Lenoci M, Metzler TJ, Otte C, Tarasovsky G, Mellon SH, Wolkowitz OM, Marmar CR, Neylan TC. Serum brain-derived neurotrophic factor predicts responses to escitalopram in chronic posttraumatic stress disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2010 Oct 1; 34(7):1279-84. PMID: 20643177; PMCID: PMC2939182.
      25. Wolkowitz OM, Epel ES, Reus VI, Mellon SH. Depression gets old fast: do stress and depression accelerate cell aging? Depress Anxiety. 2010 Apr; 27(4):327-38. PMID: 20376837.
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      26. Lin J, Epel E, Cheon J, Kroenke C, Sinclair E, Bigos M, Wolkowitz O, Mellon S, Blackburn E. Analyses and comparisons of telomerase activity and telomere length in human T and B cells: insights for epidemiology of telomere maintenance. J Immunol Methods. 2010 Jan 31; 352(1-2):71-80. PMID: 19837074; PMCID: PMC3280689.
      27. Dhabhar FS, Burke HM, Epel ES, Mellon SH, Rosser R, Reus VI, Wolkowitz OM. Low serum IL-10 concentrations and loss of regulatory association between IL-6 and IL-10 in adults with major depression. J Psychiatr Res. 2009 Jul; 43(11):962-9. PMID: 19552919.
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      28. Vinogradov S, Fisher M, Holland C, Shelly W, Wolkowitz O, Mellon SH. Is serum brain-derived neurotrophic factor a biomarker for cognitive enhancement in schizophrenia? Biol Psychiatry. 2009 Sep 15; 66(6):549-53. PMID: 19368899.
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      29. Maninger N, Wolkowitz OM, Reus VI, Epel ES, Mellon SH. Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS). Front Neuroendocrinol. 2009 Jan; 30(1):65-91. PMID: 19063914; PMCID: PMC2725024.
      30. Shi Y, Schonemann MD, Mellon SH. Regulation of P450c17 expression in the early embryo depends on GATA factors. Endocrinology. 2009 Feb; 150(2):946-56. PMID: 18832096; PMCID: PMC2646537.
      31. Zampieri S, Mellon SH, Butters TD, Nevyjel M, Covey DF, Bembi B, Dardis A. Oxidative stress in NPC1 deficient cells: protective effect of allopregnanolone. J Cell Mol Med. 2009 Sep; 13(9B):3786-96. PMID: 18774957; PMCID: PMC2832077.
      32. Wolkowitz OM, Epel ES, Mellon S. When blue turns to grey: do stress and depression accelerate cell aging? World J Biol Psychiatry. 2008; 9(1):2-5. PMID: 18273736.
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      33. Mellon SH. Neurosteroid regulation of central nervous system development. Pharmacol Ther. 2007 Oct; 116(1):107-24. PMID: 17651807; PMCID: PMC2386997.
      34. Mellon SH, Gong W, Schonemann MD. Endogenous and synthetic neurosteroids in treatment of Niemann-Pick Type C disease. Brain Res Rev. 2008 Mar; 57(2):410-20. PMID: 17629950; PMCID: PMC2323675.
      35. Mellon SH, Bair SR, Depoix C, Vigne JL, Hecht NB, Brake PB. Translin coactivates steroidogenic factor-1-stimulated transcription. Mol Endocrinol. 2007 Jan; 21(1):89-105. PMID: 17053042.
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      36. Langmade SJ, Gale SE, Frolov A, Mohri I, Suzuki K, Mellon SH, Walkley SU, Covey DF, Schaffer JE, Ory DS. Pregnane X receptor (PXR) activation: a mechanism for neuroprotection in a mouse model of Niemann-Pick C disease. Proc Natl Acad Sci U S A. 2006 Sep 12; 103(37):13807-12. PMID: 16940355; PMCID: PMC1564205.
      37. Brake PB, Bair SR, Mellon SH. DNA sequence-dependent regulation of SF-1-mediated transcription. DNA Cell Biol. 2005 Mar; 24(3):148-60. PMID: 15767781.
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      38. Mellon S, Gong W, Griffin LD. Niemann pick type C disease as a model for defects in neurosteroidogenesis. Endocr Res. 2004 Nov; 30(4):727-35. PMID: 15666818.
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      39. Griffin LD, Gong W, Verot L, Mellon SH. Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone. Nat Med. 2004 Jul; 10(7):704-11. PMID: 15208706.
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      40. Komesaroff PA, Bach MA, Danoff A, Grumbach MM, Kaplan S, Lakoski JM, Leitman D, Mellon S, Underwood LE, Leupen S. The Endocrine Society Ethics Advisory Committee: ethical aspects of conflicts of interests, October 2003. Endocrinology. 2004 Jun; 145(6):3032-41. PMID: 15140839.
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      41. Bair SR, Mellon SH. Deletion of the mouse P450c17 gene causes early embryonic lethality. Mol Cell Biol. 2004 Jun; 24(12):5383-90. PMID: 15169901; PMCID: PMC419874.
      42. Hong CY, Park JH, Ahn RS, Im SY, Choi HS, Soh J, Mellon SH, Lee K. Molecular mechanism of suppression of testicular steroidogenesis by proinflammatory cytokine tumor necrosis factor alpha. Mol Cell Biol. 2004 Apr; 24(7):2593-604. PMID: 15024051; PMCID: PMC371106.
      43. Hammer F, Compagnone NA, Vigne JL, Bair SR, Mellon SH. Transcriptional regulation of P450scc gene expression in the embryonic rodent nervous system. Endocrinology. 2004 Feb; 145(2):901-12. PMID: 14576192.
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      44. Pandey AV, Mellon SH, Miller WL. Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17. J Biol Chem. 2003 Jan 31; 278(5):2837-44. PMID: 12444089.
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      45. Mellon SH, Griffin LD. Synthesis, regulation, and function of neurosteroids. Endocr Res. 2002 Nov; 28(4):463. PMID: 12530649.
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      46. Zhang MY, Wang X, Wang JT, Compagnone NA, Mellon SH, Olson JL, Tenenhouse HS, Miller WL, Portale AA. Dietary phosphorus transcriptionally regulates 25-hydroxyvitamin D-1alpha-hydroxylase gene expression in the proximal renal tubule. Endocrinology. 2002 Feb; 143(2):587-95. PMID: 11796514.
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      47. Mellon SH, Griffin LD. Neurosteroids: biochemistry and clinical significance. Trends Endocrinol Metab. 2002 Jan-Feb; 13(1):35-43. PMID: 11750861.
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      48. Griffin LD, Mellon SH. Biosynthesis of the neurosteroid 3 alpha-hydroxy-4-pregnen-20-one (3 alpha hp), a specific inhibitor of FSH release. Endocrinology. 2001 Nov; 142(11):4617-22. PMID: 11606426.
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      49. Mellon SH, Griffin LD, Compagnone NA. Biosynthesis and action of neurosteroids. Brain Res Brain Res Rev. 2001 Nov; 37(1-3):3-12. PMID: 11744070.
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      50. Zhang P, Compagnone NA, Fiore C, Vigne JL, Culp P, Musci TJ, Mellon SH. Developmental gonadal expression of the transcription factor SET and its target gene, P450c17 (17alpha-hydroxylase/c17,20 lyase). DNA Cell Biol. 2001 Oct; 20(10):613-24. PMID: 11749720.
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      51. Fujii E, Mellon SH. Regulation of uterine gamma-aminobutyric acid(A) receptor subunit expression throughout pregnancy. Endocrinology. 2001 May; 142(5):1770-7. PMID: 11316740.
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      52. Chanoine JP, Compagnone NA, Wong AC, Mellon SH. Modulation of steroidogenesis by selenium in a novel adrenal cell line developed using targeted tumorigenesis. Biofactors. 2001; 14(1-4):229-38. PMID: 11568460.
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      53. Mellon SH, Vaudry H. Biosynthesis of neurosteroids and regulation of their synthesis. Int Rev Neurobiol. 2001; 46:33-78. PMID: 11599305.
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      54. Griffin LD, Conrad SC, Mellon SH. Current perspectives on the role of neurosteroids in PMS and depression. Int Rev Neurobiol. 2001; 46:479-92. PMID: 11599311.
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      55. Adi S, Cheng ZQ, Zhang PL, Wu NY, Mellon SH, Rosenthal SM. Opposing early inhibitory and late stimulatory effects of insulin-like growth factor-I on myogenin gene transcription. J Cell Biochem. 2000 Jun 12; 78(4):617-26. PMID: 10861859.
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      56. Compagnone NA, Zhang P, Vigne JL, Mellon SH. Novel role for the nuclear phosphoprotein SET in transcriptional activation of P450c17 and initiation of neurosteroidogenesis. Mol Endocrinol. 2000 Jun; 14(6):875-88. PMID: 10847589.
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      57. Compagnone NA, Mellon SH. Neurosteroids: biosynthesis and function of these novel neuromodulators. Front Neuroendocrinol. 2000 Jan; 21(1):1-56. PMID: 10662535.
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      58. Ingraham HA, Hirokawa Y, Roberts LM, Mellon SH, McGee E, Nachtigal MW, Visser JA. Autocrine and paracrine Müllerian inhibiting substance hormone signaling in reproduction. Recent Prog Horm Res. 2000; 55:53-67; discussion 67-8. PMID: 11036933.
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      59. Griffin LD, Mellon SH. Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes. Proc Natl Acad Sci U S A. 1999 Nov 9; 96(23):13512-7. PMID: 10557352; PMCID: PMC23979.
      60. Zhang P, Hammer F, Bair S, Wang J, Reeves WH, Mellon SH. Ku autoimmune antigen is involved in placental regulation of rat P450c17 gene transcription. DNA Cell Biol. 1999 Mar; 18(3):197-208. PMID: 10098601.
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      61. Mellon SH, Compagnone NA, Zhang P. Orphan receptors, proto-oncogenes and other nuclear factors regulate P450C17 gene transcription. Endocr Res. 1998 Aug-Nov; 24(3-4):505-13. PMID: 9888531.
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      62. Mellon SH, Bair SR. 25-Hydroxycholesterol is not a ligand for the orphan nuclear receptor steroidogenic factor-1 (SF-1). Endocrinology. 1998 Jun; 139(6):3026-9. PMID: 9607816.
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      63. Compagnone NA, Mellon SH. Dehydroepiandrosterone: a potential signalling molecule for neocortical organization during development. Proc Natl Acad Sci U S A. 1998 Apr 14; 95(8):4678-83. PMID: 9539798; PMCID: PMC22550.
      64. Zhang P, Vigne JL, Mellon SH. Polyribonucleotide phosphorylase is a double-stranded DNA-binding protein. DNA Cell Biol. 1998 Feb; 17(2):169-75. PMID: 9502433.
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      65. Compagnone NA, Salido E, Shapiro LJ, Mellon SH. Expression of steroid sulfatase during embryogenesis. Endocrinology. 1997 Nov; 138(11):4768-73. PMID: 9348204.
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      66. Zhang P, Mellon SH. Multiple orphan nuclear receptors converge to regulate rat P450c17 gene transcription: novel mechanisms for orphan nuclear receptor action. Mol Endocrinol. 1997 Jun; 11(7):891-904. PMID: 9178749.
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      67. Compagnone NA, Bair SR, Mellon SH. Characterization of adrenocortical cell lines produced by genetically targeted tumorigenesis in transgenic mice. Steroids. 1997 Feb; 62(2):238-43. PMID: 9055383.
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      68. Mellon SH, Zhang P. The testis and the adrenal are (transcriptionally) the same. Steroids. 1997 Jan; 62(1):46-52. PMID: 9029714.
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      69. Scheumann GF, Heitmann P, Teebken OE, Mössinger E, Mellon SH, Pichlmayr R. Enzymatic properties of transplanted glomerulosa cells. World J Surg. 1996 Sep; 20(7):933-8; discussion 938-9. PMID: 8678974.
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      70. Yamamoto T, Chapman BM, Johnson DC, Givens CR, Mellon SH, Soares MJ. Cytochrome P450 17 alpha-hydroxylase gene expression in differentiating rat trophoblast cells. J Endocrinol. 1996 Jul; 150(1):161-8. PMID: 8708557.
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      71. Zhang P, Han XG, Mellon SH, Hall PF. Expression of the gene for cytochrome P-450 17 alpha-hydroxylase/C17-20 lyase (CYP17) in porcine Leydig cells: identification of a DNA sequence that mediates cAMP response. Biochim Biophys Acta. 1996 Jun 3; 1307(1):73-82. PMID: 8652670.
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      72. Zhang P, Mellon SH. The orphan nuclear receptor steroidogenic factor-1 regulates the cyclic adenosine 3',5'-monophosphate-mediated transcriptional activation of rat cytochrome P450c17 (17 alpha-hydroxylase/c17-20 lyase). Mol Endocrinol. 1996 Feb; 10(2):147-58. PMID: 8825555.
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      73. Compagnone NA, Bulfone A, Rubenstein JL, Mellon SH. Steroidogenic enzyme P450c17 is expressed in the embryonic central nervous system. Endocrinology. 1995 Nov; 136(11):5212-23. PMID: 7588260.
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      74. Zhang P, Rodriguez H, Mellon SH. Transcriptional regulation of P450scc gene expression in neural and steroidogenic cells: implications for regulation of neurosteroidogenesis. Mol Endocrinol. 1995 Nov; 9(11):1571-82. PMID: 8584034.
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      75. Allen RG, Carey C, Parker JD, Mortrud MT, Mellon SH, Low MJ. Targeted ablation of pituitary pre-proopiomelanocortin cells by herpes simplex virus-1 thymidine kinase differentially regulates mRNAs encoding the adrenocorticotropin receptor and aldosterone synthase in the mouse adrenal gland. Mol Endocrinol. 1995 Aug; 9(8):1005-16. PMID: 7476975.
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      76. Cover CM, Wang JM, St Lezin E, Kurtz TW, Mellon SH. Molecular variants in the P450c11AS gene as determinants of aldosterone synthase activity in the Dahl rat model of hypertension. J Biol Chem. 1995 Jul 14; 270(28):16555-60. PMID: 7622461.
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      77. Compagnone NA, Bulfone A, Rubenstein JL, Mellon SH. Expression of the steroidogenic enzyme P450scc in the central and peripheral nervous systems during rodent embryogenesis. Endocrinology. 1995 Jun; 136(6):2689-96. PMID: 7750493.
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      78. Djavidani B, Sander M, Kreutz R, Zeh K, Bader M, Mellon SH, Vecsei P, Peters J, Ganten D. Chronic dexamethasone treatment suppresses hypertension development in the transgenic rat TGR(mREN2)27. J Hypertens. 1995 Jun; 13(6):637-45. PMID: 7594421.
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      79. Fardella CE, Rodriguez H, Hum DW, Mellon SH, Miller WL. Artificial mutations in P450c11AS (aldosterone synthase) can increase enzymatic activity: a model for low-renin hypertension? J Clin Endocrinol Metab. 1995 Mar; 80(3):1040-3. PMID: 7883820.
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      80. Mellon SH, Bair SR, Monis H. P450c11B3 mRNA, transcribed from a third P450c11 gene, is expressed in a tissue-specific, developmentally, and hormonally regulated fashion in the rodent adrenal and encodes a protein with both 11-hydroxylase and 18-hydroxylase activities. J Biol Chem. 1995 Jan 27; 270(4):1643-9. PMID: 7829497.
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      81. Saenger P, Klonari Z, Black SM, Compagnone N, Mellon SH, Fleischer A, Abrams CA, Shackelton CH, Miller WL. Prenatal diagnosis of congenital lipoid adrenal hyperplasia. J Clin Endocrinol Metab. 1995 Jan; 80(1):200-5. PMID: 7829612.
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      82. Mellon SH, Compagnone N, Sander M, Cover C, Ganten D, Djavidani B. Rodent models for studying steroids and hypertension: from fetal development to cells in culture. Steroids. 1995 Jan; 60(1):59-64. PMID: 7792817.
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      83. Givens CR, Zhang P, Bair SR, Mellon SH. Transcriptional regulation of rat cytochrome P450c17 expression in mouse Leydig MA-10 and adrenal Y-1 cells: identification of a single protein that mediates both basal and cAMP-induced activities. DNA Cell Biol. 1994 Nov; 13(11):1087-98. PMID: 7702752.
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      84. Mellon SH. Neurosteroids: biochemistry, modes of action, and clinical relevance. J Clin Endocrinol Metab. 1994 May; 78(5):1003-8. PMID: 8175951.
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      85. Sander M, Ganten D, Mellon SH. Role of adrenal renin in the regulation of adrenal steroidogenesis by corticotropin. Proc Natl Acad Sci U S A. 1994 Jan 4; 91(1):148-52. PMID: 8278356; PMCID: PMC42903.
      86. Mellon SH, Miller WL, Bair SR, Moore CC, Vigne JL, Weiner RI. Steroidogenic adrenocortical cell lines produced by genetically targeted tumorigenesis in transgenic mice. Mol Endocrinol. 1994 Jan; 8(1):97-108. PMID: 8152434.
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      87. Mellon SH, Deschepper CF. Neurosteroid biosynthesis: genes for adrenal steroidogenic enzymes are expressed in the brain. Brain Res. 1993 Dec 3; 629(2):283-92. PMID: 8111631.
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      88. Bristow J, Tee MK, Gitelman SE, Mellon SH, Miller WL. Tenascin-X: a novel extracellular matrix protein encoded by the human XB gene overlapping P450c21B. J Cell Biol. 1993 Jul; 122(1):265-78. PMID: 7686164; PMCID: PMC2119596.
      89. Moore CC, Mellon SH, Murai J, Siiteri PK, Miller WL. Structure and function of the hepatic form of 11 beta-hydroxysteroid dehydrogenase in the squirrel monkey, an animal model of glucocorticoid resistance. Endocrinology. 1993 Jul; 133(1):368-75. PMID: 8319583.
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      90. Mesiano S, Mellon SH, Jaffe RB. Mitogenic action, regulation, and localization of insulin-like growth factors in the human fetal adrenal gland. J Clin Endocrinol Metab. 1993 Apr; 76(4):968-76. PMID: 8473412.
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      91. Mesiano S, Mellon SH, Gospodarowicz D, Di Blasio AM, Jaffe RB. Basic fibroblast growth factor expression is regulated by corticotropin in the human fetal adrenal: a model for adrenal growth regulation. Proc Natl Acad Sci U S A. 1991 Jun 15; 88(12):5428-32. PMID: 1711231; PMCID: PMC51886.
      92. Malee MP, Mellon SH. Zone-specific regulation of two messenger RNAs for P450c11 in the adrenals of pregnant and nonpregnant rats. Proc Natl Acad Sci U S A. 1991 Jun 1; 88(11):4731-5. PMID: 2052554; PMCID: PMC51740.
      93. Mellon SH, Kushner JA, Vaisse C. Expression and regulation of adrenodoxin and P450scc mRNA in rodent tissues. DNA Cell Biol. 1991 Jun; 10(5):339-47. PMID: 1863358.
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      94. Mellon SH, Shively JE, Miller WL. Human proopiomelanocortin-(79-96), a proposed androgen stimulatory hormone, does not affect steroidogenesis in cultured human fetal adrenal cells. J Clin Endocrinol Metab. 1991 Jan; 72(1):19-22. PMID: 1846003.
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      95. Brentano ST, Picado-Leonard J, Mellon SH, Moore CC, Miller WL. Tissue-specific, cyclic adenosine 3',5'-monophosphate-induced, and phorbol ester-repressed transcription from the human P450c17 promoter in mouse cells. Mol Endocrinol. 1990 Dec; 4(12):1972-9. PMID: 1964490.
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      96. Elias KA, Weiner RI, Mellon SH. Effect of extracellular matrix on prolactin secretion and mRNA accumulation in GH3 cells. DNA Cell Biol. 1990 Jun; 9(5):369-75. PMID: 2115339.
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      97. Mellon SH, Miller WL. Extraadrenal steroid 21-hydroxylation is not mediated by P450c21. J Clin Invest. 1989 Nov; 84(5):1497-502. PMID: 2808702; PMCID: PMC304014.
      98. Mellon SH, Vaisse C. cAMP regulates P450scc gene expression by a cycloheximide-insensitive mechanism in cultured mouse Leydig MA-10 cells. Proc Natl Acad Sci U S A. 1989 Oct; 86(20):7775-9. PMID: 2554289; PMCID: PMC298153.
      99. Mellon SH, Baxter JD, Gutierrez-Hartmann A. Cell-specific expression of transfected brain identifier repetitive DNAs. Nucleic Acids Res. 1988 May 11; 16(9):3963-76. PMID: 2453842; PMCID: PMC336568.
      100. Lightman A, Deschepper CF, Mellon SH, Ganong WF, Naftolin F. In situ hybridization identifies renin mRNA in the rat corpus luteum. Gynecol Endocrinol. 1987 Sep; 1(3):227-33. PMID: 3332536.
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      101. West BL, Catanzaro DF, Mellon SH, Cattini PA, Baxter JD, Reudelhuber TL. Interaction of a tissue-specific factor with an essential rat growth hormone gene promoter element. Mol Cell Biol. 1987 Mar; 7(3):1193-7. PMID: 3561414; PMCID: PMC365192.
      102. Deschepper CF, Mellon SH, Cumin F, Baxter JD, Ganong WF. Analysis by immunocytochemistry and in situ hybridization of renin and its mRNA in kidney, testis, adrenal, and pituitary of the rat. Proc Natl Acad Sci U S A. 1986 Oct; 83(19):7552-6. PMID: 3532116; PMCID: PMC386757.
      103. Chung BC, Matteson KJ, Morin JE, Mellon SH, Miller WL. An approach to the molecular biology of congenital adrenal hyperplasia. Ann N Y Acad Sci. 1985; 458:238-51. PMID: 3879125.
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      104. Karin M, Eberhardt NL, Mellon SH, Malich N, Richards RI, Slater EP, Barta A, Martial JA, Baxter JD, Cathala G. Expression and hormonal regulation of the rat growth hormone gene in transfected mouse L cells. DNA. 1984; 3(2):147-55. PMID: 6723496.
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      105. Spindler SR, Mellon SH, Baxter JD. Growth hormone gene transcription is regulated by thyroid and glucocorticoid hormones in cultured rat pituitary tumor cells. J Biol Chem. 1982 Oct 10; 257(19):11627-32. PMID: 7118899.
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