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    Theodore Kurtz, MD

    TitleProfessor
    SchoolUCSF School of Medicine
    DepartmentLaboratory Medicine
    Address185 Berry Street, Suite 290
    San Francisco CA 94107
    Phone415-353-1979

       Biography 
       Education and Training
      Institution Degree School or Department Year
      University of California, San FranciscoResidency School of Medicine

       Bibliographic 
       Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Kurtz TW. John laragh: scientific pioneer. Am J Hypertens. 2014 Aug; 27(8):1010.
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      2. Houštek J, Vrbacký M, Hejzlarová K, Zídek V, Landa V, Silhavý J, Simáková M, Mlejnek P, Kazdová L, Mikšík I, Neckár J, Papoušek F, Kolár F, Kurtz TW, Pravenec M. Effects of mtDNA in SHR-mtF344 versus SHR conplastic strains on reduced OXPHOS enzyme levels, insulin resistance, cardiac hypertrophy, and systolic dysfunction. Physiol Genomics. 2014 Sep 15; 46(18):671-8.
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      3. Silhavý J, Zídek V, Mlejnek P, Landa V, Simáková M, Strnad H, Oliyarnyk O, Skop V, Kazdová L, Kurtz T, Pravenec M. Fumaric Acid Esters Can Block Pro-Inflammatory Actions of Human CRP and Ameliorate Metabolic Disturbances in Transgenic Spontaneously Hypertensive Rats. PLoS One. 2014; 9(7):e101906.
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      4. Silhavý J, Zídek V, Landa V, Simáková M, Mlejnek P, Skop V, Oliyarnyk O, Kazdová L, Mancini M, Saar K, Schulz H, Hübner N, Kurtz TW, Pravenec M. Rosuvastatin can block pro-inflammatory actions of transgenic human C-reactive protein without reducing its circulating levels. Cardiovasc Ther. 2014 Apr; 32(2):59-65.
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      5. Woeber KA, White A, Kurtz TW. Recurrent Pituitary Macroadenoma with Increased Plasma ACTH Precursors that Cross-React in a Commonly Used ACTH Immunoassay. Endocr Pract. 2014 Jan-Feb; 20(1):94-6.
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      6. Kurtz TW. When blockade of the renin-angiotensin system becomes a two-edged sword. Am J Hypertens. 2013 Jun; 26(6):721-2.
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      7. Zídek V, Mlejnek P, Simáková M, Silhavy J, Landa V, Kazdová L, Pravenec M, Kurtz TW. Tissue-specific peroxisome proliferator activated receptor gamma expression and metabolic effects of telmisartan. Am J Hypertens. 2013 Jun; 26(6):829-35.
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      8. Pravenec M, Kozich V, Krijt J, Sokolová J, Zídek V, Landa V, Simáková M, Mlejnek P, Silhavy J, Oliyarnyk O, Kazdová L, Kurtz TW. Folate deficiency is associated with oxidative stress, increased blood pressure, and insulin resistance in spontaneously hypertensive rats. Am J Hypertens. 2013 Jan; 26(1):135-40.
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      9. Takeuchi K, Yamamoto K, Ohishi M, Takeshita H, Hongyo K, Kawai T, Takeda M, Kamide K, Kurtz TW, Rakugi H. Telmisartan modulates mitochondrial function in vascular smooth muscle cells. Hypertens Res. 2013 May; 36(5):433-9.
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      10. Tomino Y, Cooper ME, Kurtz TW, Shimizu Y. Experimental models of type-2 diabetic nephropathy. Exp Diabetes Res. 2012; 2012:218917.
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      11. Houštek J, Hejzlarová K, Vrbacký M, Drahota Z, Landa V, Zídek V, Mlejnek P, Šimáková M, Šilhavy J, Mikšík I, Kazdová L, Oliyarnyk O, Kurtz T, Pravenec M. Nonsynonymous variants in mt-Nd2, mt-Nd4, and mt-Nd5 are linked to effects on oxidative phosphorylation and insulin sensitivity in rat conplastic strains. Physiol Genomics. 2012 May 1; 44(9):487-94.
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      12. Kurtz TW, Kajiya T. Differential pharmacology and benefit/risk of azilsartan compared to other sartans. Vasc Health Risk Manag. 2012; 8:133-43.
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      13. Kajiya T, Ho C, Wang J, Vilardi R, Kurtz TW. Molecular and cellular effects of azilsartan: a new generation angiotensin II receptor blocker. J Hypertens. 2011 Dec; 29(12):2476-83.
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      14. Neckár J, Šilhavy J, Zídek V, Landa V, Mlejnek P, Šimáková M, Seidman JG, Seidman C, Kazdová L, Klevstig M, Novák F, Vecka M, Papoušek F, Houštek J, Drahota Z, Kurtz TW, Kolár F, Pravenec M. CD36 overexpression predisposes to arrhythmias but reduces infarct size in spontaneously hypertensive rats: gene expression profile analysis. Physiol Genomics. 2012 Feb 1; 44(2):173-82.
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      15. Pravenec M, Kajiya T, Zídek V, Landa V, Mlejnek P, Simáková M, Silhavý J, Malínská H, Oliyarnyk O, Kazdová L, Fan J, Wang J, Kurtz TW. Effects of human C-reactive protein on pathogenesis of features of the metabolic syndrome. Hypertension. 2011 Apr; 57(4):731-7.
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      16. Tocci G, Paneni F, Palano F, Sciarretta S, Ferrucci A, Kurtz T, Mancia G, Volpe M. Angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers and diabetes: a meta-analysis of placebo-controlled clinical trials. Am J Hypertens. 2011 May; 24(5):582-90.
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      17. Pravenec M, Zídek V, Landa V, Simáková M, Mlejnek P, Silhavy J, Maxová M, Kazdová L, Seidman JG, Seidman CE, Eminaga S, Gorham J, Wang J, Kurtz TW. Age-related autocrine diabetogenic effects of transgenic resistin in spontaneously hypertensive rats: gene expression profile analysis. Physiol Genomics. 2011 Apr 12; 43(7):372-9.
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      18. Kurtz TW. Genome-wide association studies will unlock the genetic basis of hypertension.: con side of the argument. Hypertension. 2010 Dec; 56(6):1021-5.
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      19. Kurtz TW. Chlorthalidone: don't call it "thiazide-like" anymore. Hypertension. 2010 Sep; 56(3):335-7.
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      20. Mizuno CS, Chittiboyina AG, Shah FH, Patny A, Kurtz TW, Pershadsingh HA, Speth RC, Karamyan VT, Carvalho PB, Avery MA. Design, synthesis, and docking studies of novel benzimidazoles for the treatment of metabolic syndrome. J Med Chem. 2010 Feb 11; 53(3):1076-85.
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      21. Pravenec M, Kurtz TW. Recent advances in genetics of the spontaneously hypertensive rat. Curr Hypertens Rep. 2010 Feb; 12(1):5-9.
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      22. Pi J, Leung L, Xue P, Wang W, Hou Y, Liu D, Yehuda-Shnaidman E, Lee C, Lau J, Kurtz TW, Chan JY. Deficiency in the nuclear factor E2-related factor-2 transcription factor results in impaired adipogenesis and protects against diet-induced obesity. J Biol Chem. 2010 Mar 19; 285(12):9292-300.
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      23. Yamamoto K, Ohishi M, Ho C, Kurtz TW, Rakugi H. Telmisartan-induced inhibition of vascular cell proliferation beyond angiotensin receptor blockade and peroxisome proliferator-activated receptor-gamma activation. Hypertension. 2009 Dec; 54(6):1353-9.
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      24. Malínská H, Oliyarnyk O, Hubová M, Zídek V, Landa V, Simáková M, Mlejnek P, Kazdová L, Kurtz TW, Pravenec M. Increased liver oxidative stress and altered PUFA metabolism precede development of non-alcoholic steatohepatitis in SREBP-1a transgenic spontaneously hypertensive rats with genetic predisposition to hepatic steatosis. Mol Cell Biochem. 2010 Feb; 335(1-2):119-25.
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      25. Kurtz TW, Klein U. Next generation multifunctional angiotensin receptor blockers. Hypertens Res. 2009 Oct; 32(10):826-34.
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      26. Johnson MD, He L, Herman D, Wakimoto H, Wallace CA, Zidek V, Mlejnek P, Musilova A, Simakova M, Vorlicek J, Kren V, Viklicky O, Qi NR, Wang J, Seidman CE, Seidman J, Kurtz TW, Aitman TJ, Pravenec M. Dissection of chromosome 18 blood pressure and salt-sensitivity quantitative trait loci in the spontaneously hypertensive rat. Hypertension. 2009 Sep; 54(3):639-45.
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      27. Pravenec M, Kazdová L, Maxová M, Zídek V, Mlejnek P, Simáková M, Kurtz TW. Long-term pioglitazone treatment enhances lipolysis in rat adipose tissue. Int J Obes (Lond). 2008 Dec; 32(12):1848-53.
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      28. Kurtz TW. Beyond the classic angiotensin-receptor-blocker profile. Nat Clin Pract Cardiovasc Med. 2008 Jul; 5 Suppl 1:S19-26.
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      29. Pravenec M, Churchill PC, Churchill MC, Viklicky O, Kazdova L, Aitman TJ, Petretto E, Hubner N, Wallace CA, Zimdahl H, Zidek V, Landa V, Dunbar J, Bidani A, Griffin K, Qi N, Maxova M, Kren V, Mlejnek P, Wang J, Kurtz TW. Identification of renal Cd36 as a determinant of blood pressure and risk for hypertension. Nat Genet. 2008 Aug; 40(8):952-4.
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      30. Kurtz TW, Pravenec M. Molecule-specific effects of angiotensin II-receptor blockers independent of the renin-angiotensin system. Am J Hypertens. 2008 Aug; 21(8):852-9.
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      31. Sugimoto K, Kazdová L, Qi NR, Hyakukoku M, Kren V, Simáková M, Zídek V, Kurtz TW, Pravenec M. Telmisartan increases fatty acid oxidation in skeletal muscle through a peroxisome proliferator-activated receptor-gamma dependent pathway. J Hypertens. 2008 Jun; 26(6):1209-15.
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      32. Benson SC, Iguchi R, Ho CI, Yamamoto K, Kurtz TW. Inhibition of cardiovascular cell proliferation by angiotensin receptor blockers: are all molecules the same? J Hypertens. 2008 May; 26(5):973-80.
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      33. Petretto E, Sarwar R, Grieve I, Lu H, Kumaran MK, Muckett PJ, Mangion J, Schroen B, Benson M, Punjabi PP, Prasad SK, Pennell DJ, Kiesewetter C, Tasheva ES, Corpuz LM, Webb MD, Conrad GW, Kurtz TW, Kren V, Fischer J, Hubner N, Pinto YM, Pravenec M, Aitman TJ, Cook SA. Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass. Nat Genet. 2008 May; 40(5):546-52.
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      34. Mizuno CS, Chittiboyina AG, Kurtz TW, Pershadsingh HA, Avery MA. Type 2 diabetes and oral antihyperglycemic drugs. Curr Med Chem. 2008; 15(1):61-74.
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      35. Pravenec M, Kazdova L, Landa V, Zidek V, Mlejnek P, Simakova M, Jansa P, Forejt J, Kren V, Krenova D, Qi N, Wang JM, Chan D, Aitman TJ, Kurtz TW. Identification of mutated Srebf1 as a QTL influencing risk for hepatic steatosis in the spontaneously hypertensive rat. Hypertension. 2008 Jan; 51(1):148-53.
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      36. Pravenec M, Hyakukoku M, Houstek J, Zidek V, Landa V, Mlejnek P, Miksik I, Dudová-Mothejzikova K, Pecina P, Vrbacky M, Drahota Z, Vojtiskova A, Mracek T, Kazdova L, Oliyarnyk O, Wang J, Ho C, Qi N, Sugimoto K, Kurtz T. Direct linkage of mitochondrial genome variation to risk factors for type 2 diabetes in conplastic strains. Genome Res. 2007 Sep; 17(9):1319-26.
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      37. Pravenec M, Kurtz TW. Molecular genetics of experimental hypertension and the metabolic syndrome: from gene pathways to new therapies. Hypertension. 2007 May; 49(5):941-52.
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      38. Chittiboyina AG, Venkatraman MS, Mizuno CS, Desai PV, Patny A, Benson SC, Ho CI, Kurtz TW, Pershadsingh HA, Avery MA. Design and synthesis of the first generation of dithiolane thiazolidinedione- and phenylacetic acid-based PPARgamma agonists. J Med Chem. 2006 Jul 13; 49(14):4072-84.
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      39. Kurtz TW. New treatment strategies for patients with hypertension and insulin resistance. Am J Med. 2006 May; 119(5 Suppl 1):S24-30.
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      40. Sugimoto K, Qi NR, Kazdová L, Pravenec M, Ogihara T, Kurtz TW. Telmisartan but not valsartan increases caloric expenditure and protects against weight gain and hepatic steatosis. Hypertension. 2006 May; 47(5):1003-9.
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      41. Pravenec M, Kazdová L, Cahová M, Landa V, Zídek V, Mlejnek P, Simáková M, Wang J, Qi N, Kurtz TW. Fat-specific transgenic expression of resistin in the spontaneously hypertensive rat impairs fatty acid re-esterification. Int J Obes (Lond). 2006 Jul; 30(7):1157-9.
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      42. Bhagavathula N, Nerusu KC, Reddy M, Ellis CN, Chittiboyina A, Avery M, Pershadsingh HA, Kurtz TW, Varani J. BP-1107 [{2-[4-(2,4-dioxo-thiazolidin-5-ylmethyl)-phenoxy]-ethyl}-methyl-amide]: a novel synthetic thiazolidinedione that inhibits epidermal hyperplasia in psoriatic skin-severe-combined immunodeficient mouse transplants after topical application. J Pharmacol Exp Ther. 2005 Dec; 315(3):996-1004.
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      43. Qi NR, Wang J, Zidek V, Landa V, Mlejnek P, Kazdová L, Pravenec M, Kurtz TW. A new transgenic rat model of hepatic steatosis and the metabolic syndrome. Hypertension. 2005 May; 45(5):1004-11.
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      44. Kurtz TW. Treating the metabolic syndrome: telmisartan as a peroxisome proliferator-activated receptor-gamma activator. Acta Diabetol. 2005 Apr; 42 Suppl 1:S9-16.
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      45. Kurtz TW, Griffin KA, Bidani AK, Davisson RL, Hall JE. Recommendations for blood pressure measurement in humans and experimental animals: part 2: blood pressure measurement in experimental animals: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Arterioscler Thromb Vasc Biol. 2005 Mar; 25(3):e22-33.
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      46. Kurtz TW, Griffin KA, Bidani AK, Davisson RL, Hall JE. Recommendations for blood pressure measurement in animals: summary of an AHA scientific statement from the Council on High Blood Pressure Research, Professional and Public Education Subcommittee. Arterioscler Thromb Vasc Biol. 2005 Mar; 25(3):478-9.
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      47. Hubner N, Wallace CA, Zimdahl H, Petretto E, Schulz H, Maciver F, Mueller M, Hummel O, Monti J, Zidek V, Musilova A, Kren V, Causton H, Game L, Born G, Schmidt S, Müller A, Cook SA, Kurtz TW, Whittaker J, Pravenec M, Aitman TJ. Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease. Nat Genet. 2005 Mar; 37(3):243-53.
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      48. Pickering TG, Hall JE, Appel LJ, Falkner BE, Graves J, Hill MN, Jones DW, Kurtz T, Sheps SG, Roccella EJ. Recommendations for blood pressure measurement in humans and experimental animals: part 1: blood pressure measurement in humans: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Circulation. 2005 Feb 8; 111(5):697-716.
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      49. Pickering TG, Hall JE, Appel LJ, Falkner BE, Graves JW, Hill MN, Jones DH, Kurtz T, Sheps SG, Roccella EJ. Recommendations for blood pressure measurement in humans: an AHA scientific statement from the Council on High Blood Pressure Research Professional and Public Education Subcommittee. J Clin Hypertens (Greenwich). 2005 Feb; 7(2):102-9.
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      50. Pickering TG, Hall JE, Appel LJ, Falkner BE, Graves J, Hill MN, Jones DW, Kurtz T, Sheps SG, Roccella EJ. Recommendations for blood pressure measurement in humans and experimental animals: Part 1: blood pressure measurement in humans: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Hypertension. 2005 Jan; 45(1):142-61.
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      51. Kurtz TW, Griffin KA, Bidani AK, Davisson RL, Hall JE. Recommendations for blood pressure measurement in humans and experimental animals. Part 2: Blood pressure measurement in experimental animals: a statement for professionals from the subcommittee of professional and public education of the American Heart Association council on high blood pressure research. Hypertension. 2005 Feb; 45(2):299-310.
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      52. Kurtz TW, Pravenec M. Antidiabetic mechanisms of angiotensin-converting enzyme inhibitors and angiotensin II receptor antagonists: beyond the renin-angiotensin system. J Hypertens. 2004 Dec; 22(12):2253-61.
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      53. Meyer B, Bazzi H, Zidek V, Musilova A, Pravenec M, Kurtz TW, Nurnberg P, Christiano AM. A spontaneous mutation in the desmoglein 4 gene underlies hypotrichosis in a new lanceolate hair rat model. Differentiation. 2004 Dec; 72(9-10):541-7.
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      54. Venkatraman MS, Chittiboyina A, Meingassner J, Ho CI, Varani J, Ellis CN, Avery MA, Pershadsingh HA, Kurtz TW, Benson SC. Alpha-Lipoic acid-based PPARgamma agonists for treating inflammatory skin diseases. Arch Dermatol Res. 2004 Aug; 296(3):97-104.
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      55. Pershadsingh HA, Kurtz TW. Insulin-sensitizing effects of telmisartan: implications for treating insulin-resistant hypertension and cardiovascular disease. Diabetes Care. 2004 Apr; 27(4):1015.
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      56. Benson SC, Pershadsingh HA, Ho CI, Chittiboyina A, Desai P, Pravenec M, Qi N, Wang J, Avery MA, Kurtz TW. Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity. Hypertension. 2004 May; 43(5):993-1002.
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      57. Patel SN, Serghides L, Smith TG, Febbraio M, Silverstein RL, Kurtz TW, Pravenec M, Kain KC. CD36 mediates the phagocytosis of Plasmodium falciparum-infected erythrocytes by rodent macrophages. J Infect Dis. 2004 Jan 15; 189(2):204-13.
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      58. Bhagavathula N, Nerusu KC, Lal A, Ellis CN, Chittiboyina A, Avery MA, Ho CI, Benson SC, Pershadsingh HA, Kurtz TW, Varani J. Rosiglitazone inhibits proliferation, motility, and matrix metalloproteinase production in keratinocytes. J Invest Dermatol. 2004 Jan; 122(1):130-9.
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      59. Mlejnek P, Kren V, Liska F, Zídek V, Landa V, Kurtz TW, Pravenec M. The CD36 protein functions as an immunogenic domain of the RT8 alloantigen. Eur J Immunogenet. 2003 Oct; 30(5):325-7.
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      60. Pravenec M, Kazdová L, Landa V, Zidek V, Mlejnek P, Jansa P, Wang J, Qi N, Kurtz TW. Transgenic and recombinant resistin impair skeletal muscle glucose metabolism in the spontaneously hypertensive rat. J Biol Chem. 2003 Nov 14; 278(46):45209-15.
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      61. Rao SP, McRae C, Lapanowski K, Churchill M, Kurtz TW, Dunbar JC. Insulin mediated hemodynamic responses in spontaneous hypertensive rats (SHRs): effect of chromosome 4 gene transfer. Clin Exp Hypertens. 2003 Feb; 25(2):131-42.
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      62. Kurtz TW. False claims of blood pressure-independent protection by blockade of the renin angiotensin aldosterone system? Hypertension. 2003 Feb; 41(2):193-6.
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      63. Pravenec M, Kren V, Krenová D, Zídek V, Simáková M, Musilová A, Vorlícek J, Lezin ES, Kurtz TW. Genetic isolation of quantitative trait loci for blood pressure development and renal mass on chromosome 5 in the spontaneously hypertensive rat. Physiol Res. 2003; 52(3):285-9.
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      64. Pravenec M, Landa V, Zídek V, Musilová A, Kazdová L, Qi N, Wang J, St Lezin E, Kurtz TW. Transgenic expression of CD36 in the spontaneously hypertensive rat is associated with amelioration of metabolic disturbances but has no effect on hypertension. Physiol Res. 2003; 52(6):681-8.
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      65. Pravenec M, Wallace C, Aitman TJ, Kurtz TW. Gene expression profiling in hypertension research: a critical perspective. Hypertension. 2003 Jan; 41(1):3-8.
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      66. Catanzaro DF, Kurtz TW. Target organ damage in hypertension: mechanisms, prevention, and management. Am J Hypertens. 2002 Dec; 15(12):1117-8.
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      67. Qi N, Kazdova L, Zidek V, Landa V, Kren V, Pershadsingh HA, Lezin ES, Abumrad NA, Pravenec M, Kurtz TW. Pharmacogenetic evidence that cd36 is a key determinant of the metabolic effects of pioglitazone. J Biol Chem. 2002 Dec 13; 277(50):48501-7.
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      68. Churchill PC, Churchill MC, Griffin KA, Picken M, Webb RC, Kurtz TW, Bidani AK. Increased genetic susceptibility to renal damage in the stroke-prone spontaneously hypertensive rat. Kidney Int. 2002 May; 61(5):1794-800.
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      69. Pravenec M, Zídek V, Musilová A, Simáková M, Kostka V, Mlejnek P, Kren V, Krenova D, Bílá V, Míková B, Jáchymová M, Horký K, Kazdová L, St Lezin E, Kurtz TW. Genetic analysis of metabolic defects in the spontaneously hypertensive rat. Mamm Genome. 2002 May; 13(5):253-8.
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      70. Pravenec M, Kurtz TW. Genetics of Cd36 and the hypertension metabolic syndrome. Semin Nephrol. 2002 Mar; 22(2):148-53.
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      71. Kurtz TW, Catanzaro DF. New frontiers in aldosterone/mineralocorticoid biology: a reemerging force in target organ damage and hypertension. Am J Hypertens. 2001 Dec; 14(12):1276-7.
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      72. Churchill PC, Churchill MC, Bidani AK, Kurtz TW. Kidney-specific chromosome transfer in genetic hypertension: the Dahl hypothesis revisited. Kidney Int. 2001 Aug; 60(2):705-14.
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      73. Pravenec M, Zídek V, Musilová A, Vorlícek J, Kren V, St Lezin E, Kurtz TW. Genetic isolation of a blood pressure quantitative trait locus on chromosome 2 in the spontaneously hypertensive rat. J Hypertens. 2001 Jun; 19(6):1061-4.
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      74. Hajri T, Ibrahimi A, Coburn CT, Knapp FF, Kurtz T, Pravenec M, Abumrad NA. Defective fatty acid uptake in the spontaneously hypertensive rat is a primary determinant of altered glucose metabolism, hyperinsulinemia, and myocardial hypertrophy. J Biol Chem. 2001 Jun 29; 276(26):23661-6.
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      75. Griffin KA, Churchill PC, Picken M, Webb RC, Kurtz TW, Bidani AK. Differential salt-sensitivity in the pathogenesis of renal damage in SHR and stroke prone SHR. Am J Hypertens. 2001 Apr; 14(4 Pt 1):311-20.
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      76. Pravenec M, Jansa P, Kostka V, Zídek V, Kren V, Forejt J, Kurtz TW. Identification of a mutation in ADD1/SREBP-1 in the spontaneously hypertensive rat. Mamm Genome. 2001 Apr; 12(4):295-8.
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      77. Pravenec M, Landa V, Zidek V, Musilova A, Kren V, Kazdova L, Aitman TJ, Glazier AM, Ibrahimi A, Abumrad NA, Qi N, Wang JM, St Lezin EM, Kurtz TW. Transgenic rescue of defective Cd36 ameliorates insulin resistance in spontaneously hypertensive rats. Nat Genet. 2001 Feb; 27(2):156-8.
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      78. Bidani AK, Griffin KA, Churchill PC, Churchill MC, St Lezin E, Kurtz TW. Genetic susceptibility to renal injury in hypertension. Exp Nephrol. 2001; 9(6):360-5.
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      79. Ellis CN, Varani J, Fisher GJ, Zeigler ME, Pershadsingh HA, Benson SC, Chi Y, Kurtz TW. Troglitazone improves psoriasis and normalizes models of proliferative skin disease: ligands for peroxisome proliferator-activated receptor-gamma inhibit keratinocyte proliferation. Arch Dermatol. 2000 May; 136(5):609-16.
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      80. Benson S, Padmanabhan S, Kurtz TW, Pershadsingh HA. Ligands for the peroxisome proliferator-activated receptor-gamma and the retinoid X receptor-alpha exert synergistic antiproliferative effects on human coronary artery smooth muscle cells. Mol Cell Biol Res Commun. 2000 Mar; 3(3):159-64.
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      81. Benson S, Wu J, Padmanabhan S, Kurtz TW, Pershadsingh HA. Peroxisome proliferator-activated receptor (PPAR)-gamma expression in human vascular smooth muscle cells: inhibition of growth, migration, and c-fos expression by the peroxisome proliferator-activated receptor (PPAR)-gamma activator troglitazone. Am J Hypertens. 2000 Jan; 13(1 Pt 1):74-82.
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      82. St Lezin E, Liu W, Wang JM, Yang Y, Qi N, Kren V, Zidek V, Kurtz TW, Pravenec M. Genetic analysis of rat chromosome 1 and the Sa gene in spontaneous hypertension. Hypertension. 2000 Jan; 35(1 Pt 2):225-30.
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      83. St Lezin E, Griffin KA, Picken M, Churchill MC, Churchill PC, Kurtz TW, Liu W, Wang N, Kren V, Zidek V, Pravenec M, Bidani AK. Genetic isolation of a chromosome 1 region affecting susceptibility to hypertension-induced renal damage in the spontaneously hypertensive rat. Hypertension. 1999 Aug; 34(2):187-91.
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      84. Pravenec M, Zidek V, Simakova M, Kren V, Krenova D, Horky K, Jachymova M, Mikova B, Kazdova L, Aitman TJ, Churchill PC, Webb RC, Hingarh NH, Yang Y, Wang JM, Lezin EM, Kurtz TW. Genetics of Cd36 and the clustering of multiple cardiovascular risk factors in spontaneous hypertension. J Clin Invest. 1999 Jun; 103(12):1651-7.
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      85. Pravenec M, Krenová D, Kren V, Zídek V, Simáková M, Musilová A, Bottger A, van Zutphen BF, St Lezin E, Kurtz TW. Congenic strains for genetic analysis of hypertension and dyslipidemia in the spontaneously hypertensive rat. Transplant Proc. 1999 May; 31(3):1555-6.
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      86. Aitman TJ, Glazier AM, Wallace CA, Cooper LD, Norsworthy PJ, Wahid FN, Al-Majali KM, Trembling PM, Mann CJ, Shoulders CC, Graf D, St Lezin E, Kurtz TW, Kren V, Pravenec M, Ibrahimi A, Abumrad NA, Stanton LW, Scott J. Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats. Nat Genet. 1999 Jan; 21(1):76-83.
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      87. Aitman TJ, Pravenec M, Kurtz TW, Scott J. The spontaneously hypertensive rat: a model to dissect cellular defects in glucose and fatty acid metabolism. Pathol Biol (Paris). 1998 Nov; 46(9):693-4.
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      88. Kurtz TW, Gardner DG. Transcription-modulating drugs: a new frontier in the treatment of essential hypertension. Hypertension. 1998 Sep; 32(3):380-6.
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      89. Cicila GT, Dukhanina OI, Kurtz TW, Walder R, Garrett MR, Dene H, Rapp JP. Blood pressure and survival of a chromosome 7 congenic strain bred from Dahl rats. Mamm Genome. 1997 Dec; 8(12):896-902.
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      90. Churchill PC, Churchill MC, Bidani AK, Griffin KA, Picken M, Pravenec M, Kren V, St Lezin E, Wang JM, Wang N, Kurtz TW. Genetic susceptibility to hypertension-induced renal damage in the rat. Evidence based on kidney-specific genome transfer. J Clin Invest. 1997 Sep 15; 100(6):1373-82.
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      91. Szpirer C, Szpirer J, Tissir F, Stephanova E, Vanvooren P, Kurtz TW, Iwai N, Inagami T, Pravenec M, Kren V, Klinga-Levan K, Levan G. Rat chromosome 1: regional localization of seven genes (Slc9a3, Srd5a1, Esr, Tcp1, Grik5, Tnnt3, Jak2) and anchoring of the genetic linkage map to the cytogenetic map. Mamm Genome. 1997 Sep; 8(9):657-60.
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      92. Aitman TJ, Gotoda T, Evans AL, Imrie H, Heath KE, Trembling PM, Truman H, Wallace CA, Rahman A, Doré C, Flint J, Kren V, Zidek V, Kurtz TW, Pravenec M, Scott J. Quantitative trait loci for cellular defects in glucose and fatty acid metabolism in hypertensive rats. Nat Genet. 1997 Jun; 16(2):197-201.
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      93. Pravenec M, Kren V, Wang J, Kurtz TW. Linkage mapping of the cellular retinoic acid-binding protein 1 (Crabp1) gene to rat chromosome 8. Mamm Genome. 1997 Jun; 8(6):455-6.
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      94. Wang J, Pravenec M, Kren V, Kurtz TW. Linkage mapping of the Na-K-2Cl cotransporter gene (Slc12a1) to rat chromosome 3. Mamm Genome. 1997 May; 8(5):379.
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      95. Kren V, Kurtz TW, Krenova D, Bila V, Printz M, Pravenec M. Rat genome mapping using recombinant inbred strains. Transplant Proc. 1997 May; 29(3):1768.
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      96. Krenová D, Kurtz TW, Wang JM, Pravenec M, Kren V. Map of the differential segment of rat chromosome 8 in the SHR-Lx congenic strain. Transplant Proc. 1997 May; 29(3):1769.
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      97. Morikang E, Benson SC, Kurtz TW, Pershadsingh HA. Effects of thiazolidinediones on growth and differentiation of human aorta and coronary myocytes. Am J Hypertens. 1997 Apr; 10(4 Pt 1):440-6.
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      98. Kren V, Pravenec M, Lu S, Krenova D, Wang JM, Wang N, Merriouns T, Wong A, St Lezin E, Lau D, Szpirer C, Szpirer J, Kurtz TW. Genetic isolation of a region of chromosome 8 that exerts major effects on blood pressure and cardiac mass in the spontaneously hypertensive rat. J Clin Invest. 1997 Feb 15; 99(4):577-81.
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      99. Otsen M, den Bieman M, Kuiper MT, Pravenec M, Kren V, Kurtz TW, Jacob HJ, Lankhorst A, van Zutphen BF. Use of AFLP markers for gene mapping and QTL detection in the rat. Genomics. 1996 Nov 1; 37(3):289-94.
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      100. Bottger A, van Lith HA, Kren V, Krenová D, Bílá V, Vorlícek J, Zídek V, Musilová A, Zdobinská M, Wang JM, van Zutphen BF, Kurtz TW, Pravenec M. Quantitative trait loci influencing cholesterol and phospholipid phenotypes map to chromosomes that contain genes regulating blood pressure in the spontaneously hypertensive rat. J Clin Invest. 1996 Aug 1; 98(3):856-62.
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      101. Pravenec M, Kren V, Wang J, Bottger A, van Zutphen LF, Kurtz TW. Linkage mapping of the carboxyl ester lipase gene (Cel) to rat chromosome 3. Mamm Genome. 1996 Jul; 7(7):559-60.
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      102. Pravenec M, Gauguier D, Schott JJ, Buard J, Kren V, Bílá V, Szpirer C, Szpirer J, Wang JM, Huang H, St Lezin E, Spence MA, Flodman P, Printz M, Lathrop GM, Vergnaud G, Kurtz TW. A genetic linkage map of the rat derived from recombinant inbred strains. Mamm Genome. 1996 Feb; 7(2):117-27.
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      103. St Lezin EM, Pravenec M, Wong AL, Liu W, Wang N, Lu S, Jacob HJ, Roman RJ, Stec DE, Wang JM, Reid IA, Kurtz TW. Effects of renin gene transfer on blood pressure and renin gene expression in a congenic strain of Dahl salt-resistant rats. J Clin Invest. 1996 Jan 15; 97(2):522-7.
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      104. Pravenec M, Kren V, Bílá V, Krenová D, Zdobinská M, Kurtz TW. Genetic linkage maps of the rat derived from an intercross and recombinant inbred strains originating from the BN.Lx and SHR progenitors. Folia Biol (Praha). 1996; 42(4):147-53.
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      105. Huang H, Pravenec M, Wang JM, Kren V, St Lezin E, Szpirer C, Szpirer J, Kurtz TW. Mapping and sequence analysis of the gene encoding the beta subunit of the epithelial sodium channel in experimental models of hypertension. J Hypertens. 1995 Nov; 13(11):1247-51.
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      106. Cover CM, Wang JM, St Lezin E, Kurtz TW, Mellon SH. Molecular variants in the P450c11AS gene as determinants of aldosterone synthase activity in the Dahl rat model of hypertension. J Biol Chem. 1995 Jul 14; 270(28):16555-60.
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      107. Jacob HJ, Brown DM, Bunker RK, Daly MJ, Dzau VJ, Goodman A, Koike G, Kren V, Kurtz T, Lernmark A, et al. A genetic linkage map of the laboratory rat, Rattus norvegicus. Nat Genet. 1995 Jan; 9(1):63-9.
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      108. Duru K, Farrow S, Wang JM, Lockette W, Kurtz T. Frequency of a deletion polymorphism in the gene for angiotensin converting enzyme is increased in African-Americans with hypertension. Am J Hypertens. 1994 Aug; 7(8):759-62.
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      109. Kurtz TW. Genetic models of hypertension. Lancet. 1994 Jul 16; 344(8916):167-8.
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      110. Cicila GT, Rapp JP, Bloch KD, Kurtz TW, Pravenec M, Kren V, Hong CC, Quertermous T, Ng SC. Cosegregation of the endothelin-3 locus with blood pressure and relative heart weight in inbred Dahl rats. J Hypertens. 1994 Jun; 12(6):643-51.
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      111. Ginn DI, Baptista CA, Alam KY, Deng AY, Dene H, Le H, Kurtz TW, Rapp JP. Genetic analysis of alpha 2-adrenergic receptors and blood pressure using Dahl salt-sensitive rats. J Hypertens. 1994 Apr; 12(4):357-65.
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      112. Pravenec M, St Lezin EM, Kren V, Wang JM, Kurtz TW. Linkage mapping of alkaline phosphatase 1, inhibin alpha subunit, and gamma-crystallin 1 on rat chromosome 9 and Na+, K(+)-ATPase alpha 2 subunit, renin, and leukocyte common antigen on rat chromosome 13. Genomics. 1994 Jan 1; 19(1):190-1.
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      113. St Lezin EM, Kurtz TW. The renin gene and hypertension. Semin Nephrol. 1993 Nov; 13(6):581-5.
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      114. Kren V, Pravenec M, Bila V, Svobodova D, St Lezin E, Kurtz TW. Linkage between the RT8 alloantigen and interleukin 6 loci on the rat chromosome 4. Transplant Proc. 1993 Oct; 25(5):2777.
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      115. Sudhir K, Kurtz TW, Yock PG, Connolly AJ, Morris RC. Potassium preserves endothelial function and enhances aortic compliance in Dahl rats. Hypertension. 1993 Sep; 22(3):315-22.
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      116. Simon-Chazottes D, Wu H, Parmer RJ, Rozansky DJ, Szpirer J, Levan G, Kurtz TW, Szpirer C, Guenet JL, O'Connor DT. Assignment of the chromogranin A (Chga) locus to homologous regions on mouse chromosome 12 and rat chromosome 6. Genomics. 1993 Jul; 17(1):252-5.
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      117. Lezin EM, Pravenec M, Kurtz TW. New genetic models for hypertension research. Trends Cardiovasc Med. 1993 Jul-Aug; 3(4):119-23.
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      118. Pershadsingh HA, Szollosi J, Benson S, Hyun WC, Feuerstein BG, Kurtz TW. Effects of ciglitazone on blood pressure and intracellular calcium metabolism. Hypertension. 1993 Jun; 21(6 Pt 2):1020-3.
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      119. Cicila GT, Rapp JP, Wang JM, St Lezin E, Ng SC, Kurtz TW. Linkage of 11 beta-hydroxylase mutations with altered steroid biosynthesis and blood pressure in the Dahl rat. Nat Genet. 1993 Apr; 3(4):346-53.
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      120. Kurtz TW. Transgenic models of hypertension: useful tools or unusual toys? J Clin Invest. 1993 Mar; 91(3):741.
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      121. Kurtz TW, Spence MA. Genetics of essential hypertension. Am J Med. 1993 Jan; 94(1):77-84.
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      122. Iwai N, Kurtz TW, Inagami T. Further evidence of the SA gene as a candidate gene contributing to the hypertension in spontaneously hypertensive rat. Biochem Biophys Res Commun. 1992 Oct 15; 188(1):64-9.
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      123. Fenoy FJ, St Lezin E, Kurtz TW, Roman RJ. Genetic heterogeneity and differences in glomerular hemodynamics between inbred colonies of Munich-Wistar rats. J Am Soc Nephrol. 1992 Jul; 3(1):66-72.
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      124. Kurtz TW, St Lezin EM. Gene mapping in experimental hypertension. J Am Soc Nephrol. 1992 Jul; 3(1):28-34.
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      125. St Lezin E, Simonet L, Pravenec M, Kurtz TW. Hypertensive strains and normotensive 'control' strains. How closely are they related? Hypertension. 1992 May; 19(5):419-24.
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      126. Kurtz TW. Genetic approaches to hypertension. Ann Med. 1992 Apr; 24(2):81-3.
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      127. Pravenec M, Simonet L, Kren V, St Lezin E, Levan G, Szpirer J, Szpirer C, Kurtz T. Assignment of rat linkage group V to chromosome 19 by single-strand conformation polymorphism analysis of somatic cell hybrids. Genomics. 1992 Feb; 12(2):350-6.
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      128. Simonet L, St Lezin E, Kurtz TW. Sequence analysis of the alpha 1 Na+,K(+)-ATPase gene in the Dahl salt-sensitive rat. Hypertension. 1991 Nov; 18(5):689-93.
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      129. Pravenec M, Kren V, Klír P, Simonet L, Kurtz T. Identification of genes determining spontaneous hypertension. Review article. Sb Lek. 1991 Jun; 93(5-6):136-41.
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      130. Moulinier L, Venet T, Schiller NB, Kurtz TW, Morris RC, Sebastian A. Measurement of aortic blood flow by Doppler echocardiography: day to day variability in normal subjects and applicability in clinical research. J Am Coll Cardiol. 1991 May; 17(6):1326-33.
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      131. Pravenec M, Simonet L, Kren V, Kunes J, Levan G, Szpirer J, Szpirer C, Kurtz T. The rat renin gene: assignment to chromosome 13 and linkage to the regulation of blood pressure. Genomics. 1991 Mar; 9(3):466-72.
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      132. Pravenec M, Kren V, Kunes J, Scicli AG, Carretero OA, Simonet L, Kurtz TW. Cosegregation of blood pressure with a kallikrein gene family polymorphism. Hypertension. 1991 Feb; 17(2):242-6.
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      133. Kurtz TW, Casto R, Simonet L, Printz MP. Biometric genetic analysis of blood pressure in the spontaneously hypertensive rat. Hypertension. 1990 Dec; 16(6):718-24.
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      134. Mockli G, Kabra PM, Kurtz TW. Laboratory monitoring of cyclosporine levels: guidelines for the dermatologist. J Am Acad Dermatol. 1990 Dec; 23(6 Pt 2):1275-8; discussion 1278-9.
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      135. Kren V, Pravenec M, Bílá V, Daniel R, Stursa P, Hevkovský P, Kurtz TW. Genetic analysis of polydactyly-luxate syndrome in the rat. Transplant Proc. 1990 Dec; 22(6):2588-9.
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      136. Pravenec M, Kabra P, Kren V, Simonet L, Kurtz TW. Linkage between renin and fumarate hydratase genes in the rat. Transplant Proc. 1990 Dec; 22(6):2555.
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      137. Pravenec M, Kren V, Bílá V, Kabra P, Krsiaková M, Simonet L, Kurtz TW. HXB and BXH sets of recombinant inbred strains: strain distribution patterns of some genetic markers. Transplant Proc. 1990 Dec; 22(6):2557-8.
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      138. Kurtz TW, Morris RC. Sodium-calcium interactions and salt-sensitive hypertension. Am J Hypertens. 1990 Aug; 3(8 Pt 2):152S-155S.
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      139. Kurtz TW, Simonet L, Kabra PM, Wolfe S, Chan L, Hjelle BL. Cosegregation of the renin allele of the spontaneously hypertensive rat with an increase in blood pressure. J Clin Invest. 1990 Apr; 85(4):1328-32.
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      140. Karczmar GS, Kurtz T, Tavares NJ, Weiner MW. Regulation of hepatic inorganic phosphate and ATP in response to fructose loading: an in vivo 31P-NMR study. Biochim Biophys Acta. 1989 Jul 11; 1012(2):121-7.
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      141. Kurtz TW, Morris RC, Pershadsingh HA. The Zucker fatty rat as a genetic model of obesity and hypertension. Hypertension. 1989 Jun; 13(6 Pt 2):896-901.
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      142. Kurtz TW, Montano M, Chan L, Kabra P. Molecular evidence of genetic heterogeneity in Wistar-Kyoto rats: implications for research with the spontaneously hypertensive rat. Hypertension. 1989 Feb; 13(2):188-92.
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      143. Mertz GJ, Eron L, Kaufman R, Goldberg L, Raab B, Conant M, Mills J, Kurtz T, Davis LG. Prolonged continuous versus intermittent oral acyclovir treatment in normal adults with frequently recurring genital herpes simplex virus infection. Am J Med. 1988 Aug 29; 85(2A):14-9.
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      144. Kurtz TW, Morris RC. Biological variability in Wistar-Kyoto and spontaneously hypertensive rats. Hypertension. 1988 Jan; 11(1):106.
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      145. Kurtz TW, Al-Bander HA, Morris RC. "Salt-sensitive" essential hypertension in men. Is the sodium ion alone important? N Engl J Med. 1987 Oct 22; 317(17):1043-8.
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      146. Kurtz TW, Morris RC. Biological variability in Wistar-Kyoto rats. Implications for research with the spontaneously hypertensive rat. Hypertension. 1987 Jul; 10(1):127-31.
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      147. Kurtz TW, Morris RC. Attenuation of deoxycorticosterone-induced hypertension by supplemental dietary calcium. J Hypertens Suppl. 1986 Dec; 4(5):S129-31.
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      148. Kurtz TW, Portale AA, Morris RC. Evidence for a difference in vitamin D metabolism between spontaneously hypertensive and Wistar-Kyoto rats. Hypertension. 1986 Nov; 8(11):1015-20.
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      149. Kurtz TW, Kabra PM, Booth BE, Al-Bander HA, Portale AA, Serena BG, Tsai HC, Morris RC. Liquid-chromatographic measurements of inosine, hypoxanthine, and xanthine in studies of fructose-induced degradation of adenine nucleotides in humans and rats. Clin Chem. 1986 May; 32(5):782-6.
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      150. Kurtz TW, Morris RC. Sodium chloride-dependent hypertension. Hypertension. 1986 Apr; 8(4):359-60.
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      151. Kurtz TW, Morris RC. Hypertension in the recently weaned Dahl salt-sensitive rat despite a diet deficient in sodium chloride. Science. 1985 Nov 15; 230(4727):808-10.
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      152. Kurtz TW, Morris RC. Liebman and langford. Science. 1985 Apr 19; 228(4697):352-3.
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      153. Liebman BF, Langford HG, Whitescarver SA, Ott CE, Jackson B, Kurtz TW, Morris RC. Hypertension and sodium salts. Science. 1985 Apr 19; 228(4697):351-3.
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      154. Kurtz TW, Morris RC. Dietary chloride as a determinant of disordered calcium metabolism in salt-dependent hypertension. Life Sci. 1985 Mar 11; 36(10):921-9.
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      155. Kurtz TW, Morris RC. Dietary chloride and bicarbonate as determinants of desoxycorticosterone hypertension. J Hypertens Suppl. 1984 Dec; 2(3):S371-3.
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      156. Kurtz TW, Morris RC. Dietary chloride as a determinant of "sodium-dependent" hypertension. Science. 1983 Dec 9; 222(4628):1139-41.
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      157. Hsu CH, Slavicek JH, Kurtz TW. Segmental renal vascular resistance in the spontaneously hypertensive rat. Am J Physiol. 1982 Jun; 242(6):H961-6.
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      158. Hsu CH, Kurtz TW, Slavicek JM. Effect of exogenous angiotensin II on renal hemodynamics in the awake rat. Measurement of afferent arteriolar diameter by the microsphere method. Circ Res. 1980 May; 46(5):646-50.
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      159. Hsu CH, Kurtz TW, Sands CE. Intrarenal vascular resistance in glycerol-induced acute renal failure in the rat. Circ Res. 1979 Nov; 45(5):583-7.
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      160. Hsu CH, Kurtz TW, Massari PU, Ponze SA, Chang BS. Familial azotemia. Impaired urea excretion despite normal renal function. N Engl J Med. 1978 Jan 19; 298(3):117-21.
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      161. Kurtz TW, Hsu CH. Systemic hemodynamics in nephrotoxic acute renal failure. Nephron. 1978; 21(2):100-6.
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      162. Hsu CH, Kurtz TW, Waldinger TP. Cardiac output and renal blood flow in glycerol-induced acute renal failure in the rat. Circ Res. 1977 Feb; 40(2):178-82.
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      163. Jahn H, Reville P, Kurtz T, Kuntzmann F, Stahl J. [Some aspects of the action of angiotensin on the kidney]. Pathol Biol. 1967 Jun-Jul; 15(11):641-8.
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