Sign in to see private stats on your profile page — or add photo, interests, videos, mentoring, etc.

    Thomas Botton

    TitlePostdoctoral Scholar
    SchoolUCSF School of Medicine
    DepartmentDermatology
    Address555 Mission Bay Blvd South
    San Francisco CA 94158
    vCardDownload vCard

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Cerezo M, Lehraiki A, Millet A, Rouaud F, Plaisant M, Jaune E, Botton T, Ronco C, Abbe P, Amdouni H, Passeron T, Hofman V, Mograbi B, Dabert-Gay AS, Debayle D, Alcor D, Rabhi N, Annicotte JS, Héliot L, Gonzalez-Pisfil M, Robert C, Moréra S, Virougoux A, Gual P, Ali MM, Bertolotto C, Hofman P, Ballotti R, Benhida R, Rocchi S. Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance. Cancer Cell. 2016 Jun 13; 29(6):805-19. PMID: 27238082.
        View in: PubMed
      2. Talevich E, Shain AH, Botton T, Bastian BC. CNVkit: Genome-Wide Copy Number Detection and Visualization from Targeted DNA Sequencing. PLoS Comput Biol. 2016 Apr; 12(4):e1004873. PMID: 27100738.
        View in: PubMed
      3. Shain AH, Garrido M, Botton T, Talevich E, Yeh I, Sanborn JZ, Chung J, Wang NJ, Kakavand H, Mann GJ, Thompson JF, Wiesner T, Roy R, Olshen AB, Gagnon A, Gray JW, Huh N, Hur JS, Busam KJ, Scolyer RA, Cho RJ, Murali R, Bastian BC. Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway. Nat Genet. 2015 Oct; 47(10):1194-9. PMID: 26343386; PMCID: PMC4589486 [Available on 04/01/16].
      4. Menzies AM, Yeh I, Botton T, Bastian BC, Scolyer RA, Long GV. Clinical activity of the MEK inhibitor trametinib in metastatic melanoma containing BRAF kinase fusion. Pigment Cell Melanoma Res. 2015 Sep; 28(5):607-10. PMID: 26072686; PMCID: PMC4539279 [Available on 09/01/16].
      5. Yeh I, Botton T, Talevich E, Shain AH, Sparatta AJ, de la Fouchardiere A, Mully TW, North JP, Garrido MC, Gagnon A, Vemula SS, McCalmont TH, LeBoit PE, Bastian BC. Activating MET kinase rearrangements in melanoma and Spitz tumours. Nat Commun. 2015; 6:7174. PMID: 26013381; PMCID: PMC4446791.
      6. Botton T, Yeh I, Bastian BC. Melanoma BRAF fusions--letter. Clin Cancer Res. 2014 Dec 15; 20(24):6631. PMID: 25512635; PMCID: PMC4270079 [Available on 12/15/15].
      7. Wiesner T, He J, Yelensky R, Esteve-Puig R, Botton T, Yeh I, Lipson D, Otto G, Brennan K, Murali R, Garrido M, Miller VA, Ross JS, Berger MF, Sparatta A, Palmedo G, Cerroni L, Busam KJ, Kutzner H, Cronin MT, Stephens PJ, Bastian BC. Kinase fusions are frequent in Spitz tumours and spitzoid melanomas. Nat Commun. 2014; 5:3116. PMID: 24445538; PMCID: PMC4084638.
      8. Botton T, Yeh I, Nelson T, Vemula SS, Sparatta A, Garrido MC, Allegra M, Rocchi S, Bahadoran P, McCalmont TH, LeBoit PE, Burton EA, Bollag G, Ballotti R, Bastian BC. Recurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapy. Pigment Cell Melanoma Res. 2013 Nov; 26(6):845-51. PMID: 23890088; PMCID: PMC3808507.
      9. Tomic T, Botton T, Cerezo M, Robert G, Luciano F, Puissant A, Gounon P, Allegra M, Bertolotto C, Bereder JM, Tartare-Deckert S, Bahadoran P, Auberger P, Ballotti R, Rocchi S. Metformin inhibits melanoma development through autophagy and apoptosis mechanisms. Cell Death Dis. 2011; 2:e199. PMID: 21881601; PMCID: PMC3186904.
      10. Cheli Y, Giuliano S, Guiliano S, Botton T, Rocchi S, Hofman V, Hofman P, Bahadoran P, Bertolotto C, Ballotti R. Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny. Oncogene. 2011 May 19; 30(20):2307-18. PMID: 21278797.
        View in: PubMed
      11. Vauchelles R, Stalder D, Botton T, Arkowitz RA, Bassilana M. Rac1 dynamics in the human opportunistic fungal pathogen Candida albicans. PLoS One. 2010; 5(10):e15400. PMID: 21060846; PMCID: PMC2965673.
      12. Botton T, Puissant A, Cheli Y, Tomic T, Giuliano S, Fajas L, Deckert M, Ortonne JP, Bertolotto C, Tartare-Deckert S, Ballotti R, Rocchi S. Ciglitazone negatively regulates CXCL1 signaling through MITF to suppress melanoma growth. Cell Death Differ. 2011 Jan; 18(1):109-21. PMID: 20596077; PMCID: PMC3131866.
      13. Botton T, Puissant A, Bahadoran P, Annicotte JS, Fajas L, Ortonne JP, Gozzerino G, Zamoum T, Tartare-Deckert S, Bertolotto C, Ballotti R, Rocchi S. In vitro and in vivo anti-melanoma effects of ciglitazone. J Invest Dermatol. 2009 May; 129(5):1208-18. PMID: 19177142.
        View in: PubMed
      Thomas's Networks
      Related Concepts
      Derived automatically from this person's publications.
      _
      Co-Authors
      People in Profiles who have published with this person.
      _
      Related Authors
      People who share related concepts with this person.
      _
      Back to TOP