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    Timothy Durazzo, PhD

    TitleAssistant Professor
    SchoolUCSF School of Medicine
    DepartmentRadiology and Biomedical Imaging
    AddressVAMC 114
    Phone415-221-4810x4157

       Biography 
       Awards and Honors
      National Institute on Drug Abuse2009Early Career Investigators Travel Award
      SAMSA2004APEX Award for Publication Excellence in Education and Training

       Overview 
       Overview
      Timothy C. Durazzo, PhD, is an Assistant Adjunct Professor in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco and a Research Scientist at the San Francisco Veterans Affairs Medical Center. Dr. Durazzo obtained his BA in Psychology from San Diego State University in 1988, and he received his PhD in Clinical Psychology and Clinical Neuropsychology from Oklahoma State University in Stillwater, Oklahoma in 1996. Dr. Durazzo completed a one-year internship in Clinical Psychology and Clinical Neuropsychology from the Palo Alto VA Medical Center, California in 1996, followed by a postdoctoral fellowship in Clinical Neuropsychology and Neuroscience from the University of Washington School of Medicine in Seattle, Washington in 1998.

      Dr. Durazzo’s research revolves around three primary areas of interest. First, alcohol and substance use disorders. He and his colleagues are the first group to publish research specifically addressing the neurobiologic and neurocognitive effects of concurrent chronic cigarette smoking in alcohol disorders and recovery. Second, investigating chronic cigarette smoking by exploring the effects of chronic cigarette smoking of magnetic resonance-derived measures of brain morphology, metabolites, perfusion and diffusion as well as neurocognitive functioning in healthy non-substance abusing participants. Lastly, traumatic brain injury, which is focused on identifying and quantitating factors contributing to post-concussive syndrome in mild traumatic brain injuries.

      Dr. Durazzo presently serves as a reviewer for 25 scientific journals. He has 39 published articles and he has written 49 peer-reviewed articles, 56 abstracts, and 5 significant publications.

      Expertise:
      Neuroscience and Neuropsychology

      Specialty:
      Neurobiological and neurocognitive, alcohol and substance disorders, chronic cigarette smoking, traumatic brain injury

      Professional Interests:
      Magnetic resonance spectroscopy, magnetic resonance imaging, perfusion, neuropsychology, angiography, alcohol use disorders, cigarette smoking, cerebral blood flow, brain physiology

      Education and Training:
      • Associate Degree: Skyline College, San Bruno, California
      • Bachelor of Art: San Diego State University, California - Psychology
      • Doctor of Philosophy: Oklahoma State University, Stillwater - Clinical Psychology and Clinical Neuropsychology
      • Internship: Palo Alto VA Medical Center, California - Clinical Psychology and Clinical Neuropsychology
      • Postdoctoral Fellowship: University of Washington School of Medicine, Seattle - Clinical Neuropsychology and Neuroscience

       Interests
      Magnetic resonance spectroscopy, magnetic resonance imaging, perfusion, neuropsychology, angiography, alcohol use disorders, cigarette smoking, cerebral blood flow, brain physiology.


       Bibliographic 
       Publications
      Publications by year:
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      1. Meyerhoff DJ, Durazzo TC, Ende G. Chronic alcohol consumption, abstinence and relapse: brain proton magnetic resonance spectroscopy studies in animals and humans. Curr Top Behav Neurosci. 2013; 13:511-40.
        View in: PubMed
      2. Yeo RA, Thoma RJ, Gasparovic C, Monnig M, Harlaar N, Calhoun VD, Kalyanam R, Mayer AR, Durazzo TC, Hutchison KE. Neurometabolite concentration and clinical features of chronic alcohol use: A proton magnetic resonance spectroscopy study. Psychiatry Res. 2013 Feb 28; 211(2):141-7.
        View in: PubMed
      3. Durazzo TC, Insel PS, Weiner MW. Greater regional brain atrophy rate in healthy elderly subjects with a history of cigarette smoking. Alzheimers Dement. 2012 Nov; 8(6):513-9.
        View in: PubMed
      4. Abé C, Mon A, Durazzo TC, Pennington DL, Schmidt TP, Meyerhoff DJ. Polysubstance and alcohol dependence: Unique abnormalities of magnetic resonance-derived brain metabolite levels. Drug Alcohol Depend. 2012 Oct 30.
        View in: PubMed
      5. Durazzo TC, Hutchison KE, Fryer SL, Mon A, Meyerhoff DJ. Associations of Cigarette Smoking and Polymorphisms in Brain-Derived Neurotrophic Factor and Catechol-O-Methyltransferase with Neurocognition in Alcohol Dependent Individuals during Early Abstinence. Front Pharmacol. 2012; 3:178.
        View in: PubMed
      6. Mon A, Durazzo TC, Gazdzinski S, Hutchison KE, Pennington D, Meyerhoff DJ. Brain-derived neurotrophic factor genotype is associated with brain gray and white matter tissue volumes recovery in abstinent alcohol-dependent individuals. Genes Brain Behav. 2013 Feb; 12(1):98-107.
        View in: PubMed
      7. Mon A, Durazzo TC, Meyerhoff DJ. Glutamate, GABA, and other cortical metabolite concentrations during early abstinence from alcohol and their associations with neurocognitive changes. Drug Alcohol Depend. 2012 Sep 1; 125(1-2):27-36.
        View in: PubMed
      8. Durazzo TC, Mon A, Gazdzinski S, Meyerhoff DJ. Chronic cigarette smoking in alcohol dependence: associations with cortical thickness and N-acetylaspartate levels in the extended brain reward system. Addict Biol. 2013 Mar; 18(2):379-91.
        View in: PubMed
      9. Durazzo TC, Meyerhoff DJ, Nixon SJ. A comprehensive assessment of neurocognition in middle-aged chronic cigarette smokers. Drug Alcohol Depend. 2012 Apr 1; 122(1-2):105-11.
        View in: PubMed
      10. Mon A, Delucchi K, Durazzo TC, Gazdzinski S, Meyerhoff DJ. A mathematical formula for prediction of gray and white matter volume recovery in abstinent alcohol dependent individuals. Psychiatry Res. 2011 Nov 30; 194(2):198-204.
        View in: PubMed
      11. Cardenas VA, Durazzo TC, Gazdzinski S, Mon A, Studholme C, Meyerhoff DJ. Brain morphology at entry into treatment for alcohol dependence is related to relapse propensity. Biol Psychiatry. 2011 Sep 15; 70(6):561-7.
        View in: PubMed
      12. Durazzo TC, Tosun D, Buckley S, Gazdzinski S, Mon A, Fryer SL, Meyerhoff DJ. Cortical thickness, surface area, and volume of the brain reward system in alcohol dependence: relationships to relapse and extended abstinence. Alcohol Clin Exp Res. 2011 Jun; 35(6):1187-200.
        View in: PubMed
      13. Durazzo TC, Meyerhoff DJ, Nixon SJ. Chronic cigarette smoking: implications for neurocognition and brain neurobiology. Int J Environ Res Public Health. 2010 Oct; 7(10):3760-91.
        View in: PubMed
      14. Durazzo TC, Fryer SL, Rothlind JC, Vertinski M, Gazdzinski S, Mon A, Meyerhoff DJ. Measures of learning, memory and processing speed accurately predict smoking status in short-term abstinent treatment-seeking alcohol-dependent individuals. Alcohol Alcohol. 2010 Nov-Dec; 45(6):507-13.
        View in: PubMed
      15. Gazdzinski S, Durazzo TC, Mon A, Meyerhoff DJ. Body mass index is associated with brain metabolite levels in alcohol dependence--a multimodal magnetic resonance study. Alcohol Clin Exp Res. 2010 Dec; 34(12):2089-96.
        View in: PubMed
      16. Durazzo TC, Gazdzinski S, Mon A, Meyerhoff DJ. Cortical perfusion in alcohol-dependent individuals during short-term abstinence: relationships to resumption of hazardous drinking after treatment. Alcohol. 2010 May; 44(3):201-10.
        View in: PubMed
      17. Durazzo TC, Pathak V, Gazdzinski S, Mon A, Meyerhoff DJ. Metabolite levels in the brain reward pathway discriminate those who remain abstinent from those who resume hazardous alcohol consumption after treatment for alcohol dependence. J Stud Alcohol Drugs. 2010 Mar; 71(2):278-89.
        View in: PubMed
      18. Gazdzinski S, Durazzo TC, Mon A, Yeh PH, Meyerhoff DJ. Cerebral white matter recovery in abstinent alcoholics--a multimodality magnetic resonance study. Brain. 2010 Apr; 133(Pt 4):1043-53.
        View in: PubMed
      19. Gazdzinski S, Millin R, Kaiser LG, Durazzo TC, Mueller SG, Weiner MW, Meyerhoff DJ. BMI and neuronal integrity in healthy, cognitively normal elderly: a proton magnetic resonance spectroscopy study. Obesity (Silver Spring). 2010 Apr; 18(4):743-8.
        View in: PubMed
      20. Wang JJ, Durazzo TC, Gazdzinski S, Yeh PH, Mon A, Meyerhoff DJ. MRSI and DTI: a multimodal approach for improved detection of white matter abnormalities in alcohol and nicotine dependence. NMR Biomed. 2009 Jun; 22(5):516-22.
        View in: PubMed
      21. Yeh PH, Simpson K, Durazzo TC, Gazdzinski S, Meyerhoff DJ. Tract-Based Spatial Statistics (TBSS) of diffusion tensor imaging data in alcohol dependence: abnormalities of the motivational neurocircuitry. Psychiatry Res. 2009 Jul 15; 173(1):22-30.
        View in: PubMed
      22. Mon A, Durazzo TC, Gazdzinski S, Meyerhoff DJ. The impact of chronic cigarette smoking on recovery from cortical gray matter perfusion deficits in alcohol dependence: longitudinal arterial spin labeling MRI. Alcohol Clin Exp Res. 2009 Aug; 33(8):1314-21.
        View in: PubMed
      23. Durazzo TC, Gazdzinski S, Yeh PH, Meyerhoff DJ. Combined neuroimaging, neurocognitive and psychiatric factors to predict alcohol consumption following treatment for alcohol dependence. Alcohol Alcohol. 2008 Nov-Dec; 43(6):683-91.
        View in: PubMed
      24. Durazzo TC, Rothlind JC, Gazdzinski S, Meyerhoff DJ. The relationships of sociodemographic factors, medical, psychiatric, and substance-misuse co-morbidities to neurocognition in short-term abstinent alcohol-dependent individuals. Alcohol. 2008 Sep; 42(6):439-49.
        View in: PubMed
      25. Meyerhoff DJ, Durazzo TC. Proton magnetic resonance spectroscopy in alcohol use disorders: a potential new endophenotype? Alcohol Clin Exp Res. 2008 Jul; 32(7):1146-58.
        View in: PubMed
      26. Gazdzinski S, Durazzo TC, Weiner MW, Meyerhoff DJ. Are treated alcoholics representative of the entire population with alcohol use disorders? A magnetic resonance study of brain injury. Alcohol. 2008 Mar; 42(2):67-76.
        View in: PubMed
      27. Gazdzinski S, Durazzo TC, Yeh PH, Hardin D, Banys P, Meyerhoff DJ. Chronic cigarette smoking modulates injury and short-term recovery of the medial temporal lobe in alcoholics. Psychiatry Res. 2008 Feb 28; 162(2):133-45.
        View in: PubMed
      28. Durazzo TC, Rothlind JC, Cardenas VA, Studholme C, Weiner MW, Meyerhoff DJ. Chronic cigarette smoking and heavy drinking in human immunodeficiency virus: consequences for neurocognition and brain morphology. Alcohol. 2007 Nov; 41(7):489-501.
        View in: PubMed
      29. Yeh PH, Gazdzinski S, Durazzo TC, Sjöstrand K, Meyerhoff DJ. Hierarchical linear modeling (HLM) of longitudinal brain structural and cognitive changes in alcohol-dependent individuals during sobriety. Drug Alcohol Depend. 2007 Dec 1; 91(2-3):195-204.
        View in: PubMed
      30. Durazzo TC, Gazdzinski S, Meyerhoff DJ. The neurobiological and neurocognitive consequences of chronic cigarette smoking in alcohol use disorders. Alcohol Alcohol. 2007 May-Jun; 42(3):174-85.
        View in: PubMed
      31. Durazzo TC, Meyerhoff DJ. Neurobiological and neurocognitive effects of chronic cigarette smoking and alcoholism. Front Biosci. 2007; 12:4079-100.
        View in: PubMed
      32. Durazzo TC, Rothlind JC, Gazdzinski S, Banys P, Meyerhoff DJ. Chronic smoking is associated with differential neurocognitive recovery in abstinent alcoholic patients: a preliminary investigation. Alcohol Clin Exp Res. 2007 Jul; 31(7):1114-27.
        View in: PubMed
      33. Cardenas VA, Studholme C, Gazdzinski S, Durazzo TC, Meyerhoff DJ. Deformation-based morphometry of brain changes in alcohol dependence and abstinence. Neuroimage. 2007 Feb 1; 34(3):879-87.
        View in: PubMed
      34. Durazzo TC, Cardenas VA, Studholme C, Weiner MW, Meyerhoff DJ. Non-treatment-seeking heavy drinkers: effects of chronic cigarette smoking on brain structure. Drug Alcohol Depend. 2007 Feb 23; 87(1):76-82.
        View in: PubMed
      35. Durazzo TC, Rothlind JC, Gazdzinski S, Banys P, Meyerhoff DJ. A comparison of neurocognitive function in nonsmoking and chronically smoking short-term abstinent alcoholics. Alcohol. 2006 May; 39(1):1-11.
        View in: PubMed
      36. Gazdzinski S, Durazzo T, Jahng GH, Ezekiel F, Banys P, Meyerhoff D. Effects of chronic alcohol dependence and chronic cigarette smoking on cerebral perfusion: a preliminary magnetic resonance study. Alcohol Clin Exp Res. 2006 Jun; 30(6):947-58.
        View in: PubMed
      37. Durazzo TC, Gazdzinski S, Rothlind JC, Banys P, Meyerhoff DJ. Brain metabolite concentrations and neurocognition during short-term recovery from alcohol dependence: Preliminary evidence of the effects of concurrent chronic cigarette smoking. Alcohol Clin Exp Res. 2006 Mar; 30(3):539-51.
        View in: PubMed
      38. Meyerhoff DJ, Tizabi Y, Staley JK, Durazzo TC, Glass JM, Nixon SJ. Smoking comorbidity in alcoholism: neurobiological and neurocognitive consequences. Alcohol Clin Exp Res. 2006 Feb; 30(2):253-64.
        View in: PubMed
      39. Gazdzinski S, Durazzo TC, Studholme C, Song E, Banys P, Meyerhoff DJ. Quantitative brain MRI in alcohol dependence: preliminary evidence for effects of concurrent chronic cigarette smoking on regional brain volumes. Alcohol Clin Exp Res. 2005 Aug; 29(8):1484-95.
        View in: PubMed
      40. Gazdzinski S, Durazzo TC, Meyerhoff DJ. Temporal dynamics and determinants of whole brain tissue volume changes during recovery from alcohol dependence. Drug Alcohol Depend. 2005 Jun 1; 78(3):263-73.
        View in: PubMed
      41. Durazzo TC, Gazdzinski S, Banys P, Meyerhoff DJ. Cigarette smoking exacerbates chronic alcohol-induced brain damage: a preliminary metabolite imaging study. Alcohol Clin Exp Res. 2004 Dec; 28(12):1849-60.
        View in: PubMed
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