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Xiao Hu, PhD

TitleAssociate Professor
SchoolUCSF School of Nursing
DepartmentPhysiological Nursing
Address2 Koret Way
San Francisco CA 94143
Phone415-476-4412
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    Collapse Biography 
    Collapse Awards and Honors
    UCLA2008 - 2010Clinical and Translational Science Institute Scholar
    Innocentive 2013 - 2013Winner of NASA-Innocentive Challenge on Noninvasive Intracranial Pressure

    Collapse Overview 
    Collapse Overview
    My research program’s goal is to innovate intelligent informatics systems to enhance healthcare professionals’ ability in utilizing Big Clinical Data to achieve more precise assessment and anticipation of patient state changes. Our team’s core expertise lies in various physiological signal modeling and processing and developing machine learning models. Our projects are interdisciplinary in nature. We are keen in learning new clinical/physiological problems that can be approached using our core engineering expertise. We are capable of developing and validating prototypes of intelligent systems equipped with our algorithms. Our current projects cover problems derived from neurocritical care and neurosurgical care of patients as well as from general in-hospital patient monitoring.


    Collapse Research 
    Collapse Research Activities and Funding
    Develop&validate SuperAlarm to detect patient deterioration with few false alarms
    NIH/NHLBI R01HL128679Jul 20, 2015 - Apr 30, 2019
    Role: Principal Investigator
    ICP Elevation Alerting Based on a Predictive Model Hosting Platform
    NIH/NINDS R01NS076738May 15, 2012 - Jan 31, 2016
    Role: Principal Investigator
    Continuous-Signal Driven Predictive Models in Neurological Intensive Care Units
    NIH/NINDS R01NS066008May 15, 2009 - Apr 30, 2013
    Role: Principal Investigator
    Intracranial Pressure Latency as a Biomarker of Cerebral Vasculature Status
    NIH/NINDS R21NS059797Feb 15, 2008 - Jan 31, 2011
    Role: Principal Investigator
    Data Mining Based Noninvasive Intracranial Pressure Assessment
    NIH/NINDS R21NS055998Mar 1, 2007 - Feb 28, 2010
    Role: Principal Investigator
    A Data Fusion Method for Bedside Monitoring of Lumped Cerebral Arterial Radii
    NIH/NINDS R21NS055045Jan 15, 2007 - Dec 31, 2009
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Global Health
    Collapse Student Projects

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Ryu J, Ko N, Hu X, Shadden SC. Numerical Investigation of Vasospasm Detection by Extracranial Blood Velocity Ratios. Cerebrovasc Dis. 2017 Feb 28; 43(5-6):214-222. PMID: 28241122.
      View in: PubMed
    2. Pelter MM, Stotts J, Spolini K, Nguyen J, Sin E, Hu X. Developing a Clinical Alarms Management Committee at an Academic Medical Center. Biomed Instrum Technol. 2017 Feb; 51(s2):21-29. PMID: 28296458.
      View in: PubMed
    3. Ding Q, Bai Y, Erol YB, Salas-Boni R, Zhang X, Hu X. Robust QRS peak detection by multimodal information fusion of ECG and blood pressure signals. Physiol Meas. 2016 Nov; 37(11):N84-N95. PMID: 27734807.
      View in: PubMed
    4. Pelter MM, Fidler R, Hu X. Research: Association of Low-Amplitude QRSs with False-Positive Asystole Alarms. Biomed Instrum Technol. 2016 Sep-Oct; 50(5):329-35. PMID: 27632038.
      View in: PubMed
    5. Pelter MM, Loranger D, Kozik TM, Fidler R, Hu X, Carey MG, et al. Unplanned transfer from the telemetry unit to the intensive care unit in hospitalized patients with suspected acute coronary syndrome. J Electrocardiol. 2016 Aug 26. PMID: 27623400.
      View in: PubMed
    6. Bai Y, Do D, Ding Q, Arroyo Palacios J, Shahriari Y, Pelter M, Boyle N, Fidler R, Hu X, et al. Is the Sequence of SuperAlarm Triggers more Predictive than Sequence of the Currently Utilized Patient Monitor Alarms? IEEE Trans Biomed Eng. 2016 Jun 30. PMID: 27390164.
      View in: PubMed
    7. Arroyo-Palacios J, Rudz M, Fidler R, Smith W, Ko N, Park S, Bai Y, Hu X. Characterization of Shape Differences Among ICP Pulses Predicts Outcome of External Ventricular Drainage Weaning Trial. Neurocrit Care. 2016 Apr 22. PMID: 27106888.
      View in: PubMed
    8. Miaskowski C, Cooper BA, Aouizerat B, Melisko M, Chen LM, Dunn L, Hu X, Kober KM, Mastick J, Levine JD, Hammer M, Wright F, Harris J, Armes J, Furlong E, Fox P, Ream E, Maguire R, Kearney N. The symptom phenotype of oncology outpatients remains relatively stable from prior to through 1 week following chemotherapy. Eur J Cancer Care (Engl). 2016 Jan 18. PMID: 26777053.
      View in: PubMed
    9. Hamilton R, Fuller J, Baldwin K, Vespa P, Hu X, Bergsneider M. Relative Position of the Third Characteristic Peak of the Intracranial Pressure Pulse Waveform Morphology Differentiates Normal-Pressure Hydrocephalus Shunt Responders and Nonresponders. Acta Neurochir Suppl. 2016; 122:339-45. PMID: 27165933.
      View in: PubMed
    10. Connolly M, Vespa P, Hu X. Characterization of Cerebral Vascular Response to EEG Bursts Using ICP Pulse Waveform Template Matching. Acta Neurochir Suppl. 2016; 122:291-4. PMID: 27165924.
      View in: PubMed
    11. Connolly M, Liou R, Vespa P, Hu X. Identification of an Intracranial Pressure (ICP) Response Function from Continuously Acquired Electroencephalographic and ICP Signals in Burst-Suppressed Patients. Acta Neurochir Suppl. 2016; 122:225-8. PMID: 27165911.
      View in: PubMed
    12. Bai Y, Sow D, Vespa P, Hu X. Real-Time Processing of Continuous Physiological Signals in a Neurocritical Care Unit on a Stream Data Analytics Platform. Acta Neurochir Suppl. 2016; 122:75-80. PMID: 27165881.
      View in: PubMed
    13. Ding Q, Bai Y, Tinoco A, Mortara D, Do D, Boyle NG, Pelter MM, Hu X. Developing new predictive alarms based on ECG metrics for bradyasystolic cardiac arrest. Physiol Meas. 2015 Dec; 36(12):2405-22. PMID: 26502065.
      View in: PubMed
    14. Ryu J, Hu X, Shadden SC. A Coupled Lumped-Parameter and Distributed Network Model for Cerebral Pulse-Wave Hemodynamics. J Biomech Eng. 2015 Oct; 137(10):101009. PMID: 26287937.
      View in: PubMed
    15. Fidler R, Bond R, Finlay D, Guldenring D, Gallagher A, Pelter M, Drew B, Hu X. Human factors approach to evaluate the user interface of physiologic monitoring. J Electrocardiol. 2015 Nov-Dec; 48(6):982-7. PMID: 26375330.
      View in: PubMed
    16. Do DH, Hayase J, Tiecher RD, Bai Y, Hu X, Boyle NG. ECG changes on continuous telemetry preceding in-hospital cardiac arrests. J Electrocardiol. 2015 Nov-Dec; 48(6):1062-8. PMID: 26362882.
      View in: PubMed
    17. Connolly M, Vespa P, Pouratian N, Gonzalez NR, Hu X. Characterization of the relationship between intracranial pressure and electroencephalographic monitoring in burst-suppressed patients. Neurocrit Care. 2015 Apr; 22(2):212-20. PMID: 25142827; PMCID: PMC4336620.
    18. Salas-Boni R, Bai Y, Hu X. Cumulative Time Series Representation for Code Blue prediction in the Intensive Care Unit. AMIA Jt Summits Transl Sci Proc. 2015; 2015:162-7. PMID: 26306261; PMCID: PMC4525278.
    19. Kim S, Scalzo F, Telesca D, Hu X. Ensemble of sparse classifiers for high-dimensional biological data. Int J Data Min Bioinform. 2015; 12(2):167-83. PMID: 26510301.
      View in: PubMed
    20. Drew BJ, Harris P, Zègre-Hemsey JK, Mammone T, Schindler D, Salas-Boni R, Bai Y, Tinoco A, Ding Q, Hu X. Insights into the problem of alarm fatigue with physiologic monitor devices: a comprehensive observational study of consecutive intensive care unit patients. PLoS One. 2014; 9(10):e110274. PMID: 25338067; PMCID: PMC4206416.
    21. Bai Y, Do DH, Harris PR, Schindler D, Boyle NG, Drew BJ, Hu X. Integrating monitor alarms with laboratory test results to enhance patient deterioration prediction. J Biomed Inform. 2015 Feb; 53:81-92. PMID: 25240252.
      View in: PubMed
    22. Salas-Boni R, Bai Y, Harris PR, Drew BJ, Hu X. False ventricular tachycardia alarm suppression in the ICU based on the discrete wavelet transform in the ECG signal. J Electrocardiol. 2014 Nov-Dec; 47(6):775-80. PMID: 25172188.
      View in: PubMed
    23. Connolly M, He X, Gonzalez N, Vespa P, DiStefano J, Hu X. Reproduction of consistent pulse-waveform changes using a computational model of the cerebral circulatory system. Med Eng Phys. 2014 Mar; 36(3):354-63. PMID: 24389244; PMCID: PMC4270797.
    24. Hu X, Do D, Bai Y, Boyle NG. A case-control study of non-monitored ECG metrics preceding in-hospital bradyasystolic cardiac arrest: implication for predictive monitor alarms. J Electrocardiol. 2013 Nov-Dec; 46(6):608-15. PMID: 24034301.
      View in: PubMed
    25. Asgari S, Vespa P, Hu X. Is there any association between cerebral vasoconstriction/vasodilatation and microdialysis Lactate to Pyruvate ratio increase? Neurocrit Care. 2013 Aug; 19(1):56-64. PMID: 23733172.
      View in: PubMed
    26. Scalzo F, Alger JR, Hu X, Saver JL, Dani KA, Muir KW, Demchuk AM, Coutts SB, Luby M, Warach S, Liebeskind DS. Multi-center prediction of hemorrhagic transformation in acute ischemic stroke using permeability imaging features. Magn Reson Imaging. 2013 Jul; 31(6):961-9. PMID: 23587928; PMCID: PMC3676704.
    27. Scalzo F, Hu X. Semi-supervised detection of intracranial pressure alarms using waveform dynamics. Physiol Meas. 2013 Apr; 34(4):465-78. PMID: 23524637.
      View in: PubMed
    28. Xu P, Hu X, Yao D. Improved wavelet entropy calculation with window functions and its preliminary application to study intracranial pressure. Comput Biol Med. 2013 Jun; 43(5):425-33. PMID: 23566389.
      View in: PubMed
    29. Tsiokos C, Hu X, Pouratian N. 200-300Hz movement modulated oscillations in the internal globus pallidus of patients with Parkinson's Disease. Neurobiol Dis. 2013 Jun; 54:464-74. PMID: 23388190; PMCID: PMC3629001.
    30. Gonzalez NR, Hamilton R, Bilgin-Freiert A, Dusick J, Vespa P, Hu X, Asgari S. Cerebral hemodynamic and metabolic effects of remote ischemic preconditioning in patients with subarachnoid hemorrhage. Acta Neurochir Suppl. 2013; 115:193-8. PMID: 22890668.
      View in: PubMed
    31. Asgari S, Gonzalez N, Subudhi AW, Hamilton R, Vespa P, Bergsneider M, Roach RC, Hu X. Continuous detection of cerebral vasodilatation and vasoconstriction using intracranial pulse morphological template matching. PLoS One. 2012; 7(11):e50795. PMID: 23226385; PMCID: PMC3511284.
    32. Kim S, Hamilton R, Pineles S, Bergsneider M, Hu X. Noninvasive intracranial hypertension detection utilizing semisupervised learning. IEEE Trans Biomed Eng. 2013 Apr; 60(4):1126-33. PMID: 23193303; PMCID: PMC3609870.
    33. Hu X, Gonzalez N, Bergsneider M. Steady-state indicators of the intracranial pressure dynamic system using geodesic distance of the ICP pulse waveform. Physiol Meas. 2012 Dec; 33(12):2017-31. PMID: 23151442; PMCID: PMC3547535.
    34. Hamilton R, Baldwin K, Fuller J, Vespa P, Hu X, Bergsneider M. Intracranial pressure pulse waveform correlates with aqueductal cerebrospinal fluid stroke volume. J Appl Physiol (1985). 2012 Nov; 113(10):1560-6. PMID: 22995390; PMCID: PMC3524656.
    35. Lu J, Speier W, Hu X, Pouratian N. The effects of stimulus timing features on P300 speller performance. Clin Neurophysiol. 2013 Feb; 124(2):306-14. PMID: 22939456; PMCID: PMC3595069.
    36. Scalzo F, Liebeskind D, Hu X. Reducing false intracranial pressure alarms using morphological waveform features. IEEE Trans Biomed Eng. 2013 Jan; 60(1):235-9. PMID: 22851230; PMCID: PMC3547536.
    37. Scalzo F, Hao Q, Alger JR, Hu X, Liebeskind DS. Regional prediction of tissue fate in acute ischemic stroke. Ann Biomed Eng. 2012 Oct; 40(10):2177-87. PMID: 22592291; PMCID: PMC3647682.
    38. Hu X, Sapo M, Nenov V, Barry T, Kim S, Do DH, Boyle N, Martin N. Predictive combinations of monitor alarms preceding in-hospital code blue events. J Biomed Inform. 2012 Oct; 45(5):913-21. PMID: 22465785.
      View in: PubMed
    39. Scalzo F, Hamilton R, Asgari S, Kim S, Hu X. Intracranial hypertension prediction using extremely randomized decision trees. Med Eng Phys. 2012 Oct; 34(8):1058-65. PMID: 22401795; PMCID: PMC3399093.
    40. Scalzo F, Bergsneider M, Vespa PM, Martin NA, Hu X. Intracranial pressure signal morphology: real-time tracking. IEEE Pulse. 2012 Mar; 3(2):49-52. PMID: 22481746.
      View in: PubMed
    41. Hu X, Hamilton R, Baldwin K, Vespa PM, Bergsneider M. Automated extraction of decision rules for predicting lumbar drain outcome by analyzing overnight intracranial pressure. Acta Neurochir Suppl. 2012; 114:207-12. PMID: 22327694.
      View in: PubMed
    42. Hamilton R, Dye J, Frew A, Baldwin K, Hu X, Bergsneider M. Quantification of pulsatile cerebrospinal fluid flow within the prepontine cistern. Acta Neurochir Suppl. 2012; 114:191-5. PMID: 22327691.
      View in: PubMed
    43. Kasprowicz M, Bergsneider M, Czosnyka M, Hu X. Association between ICP pulse waveform morphology and ICP B waves. Acta Neurochir Suppl. 2012; 114:29-34. PMID: 22327660.
      View in: PubMed
    44. Asgari S, Vespa PM, Bergsneider M, Hu X. Latency relationships between cerebral blood flow velocity and intracranial pressure. Acta Neurochir Suppl. 2012; 114:5-9. PMID: 22327656.
      View in: PubMed
    45. Glenn TC, Sherma AK, McArthur DL, Hu X, Hanuscin CR, Furreedan MS, Hovda DA, Vespa PM, Martin NA. The linear relationship between transcranial Doppler pulsatility indices and intracranial pressure is influenced by traumatic brain injury and vasospasm. Acta Neurochir Suppl. 2012; 114:11-5. PMID: 22327657.
      View in: PubMed
    46. Hamilton RB, Baldwin K, Vespa P, Bergsneider M, Hu X. Subpeak regional analysis of intracranial pressure waveform morphology based on cerebrospinal fluid hydrodynamics in the cerebral aqueduct and prepontine cistern. Conf Proc IEEE Eng Med Biol Soc. 2012; 2012:3935-8. PMID: 23366788.
      View in: PubMed
    47. Scalzo F, Asgari S, Kim S, Bergsneider M, Hu X. Bayesian tracking of intracranial pressure signal morphology. Artif Intell Med. 2012 Feb; 54(2):115-23. PMID: 21968205; PMCID: PMC3288115.
    48. Asgari S, Vespa P, Bergsneider M, Hu X. Lack of consistent intracranial pressure pulse morphological changes during episodes of microdialysis lactate/pyruvate ratio increase. Physiol Meas. 2011 Oct; 32(10):1639-51. PMID: 21904021; PMCID: PMC3334323.
    49. Asgari S, Bergsneider M, Hamilton R, Vespa P, Hu X. Consistent changes in intracranial pressure waveform morphology induced by acute hypercapnic cerebral vasodilatation. Neurocrit Care. 2011 Aug; 15(1):55-62. PMID: 21052864; PMCID: PMC3130848.
    50. Yang L, Zhao M, Peng C, Hu X, Feng H, Ji Z. Waveform descriptor for pulse onset detection of intracranial pressure signal. Med Eng Phys. 2012 Mar; 34(2):179-86. PMID: 21807549.
      View in: PubMed
    51. Asgari S, Subudhi AW, Roach RC, Liebeskind DS, Bergsneider M, Hu X. An extended model of intracranial latency facilitates non-invasive detection of cerebrovascular changes. J Neurosci Methods. 2011 Apr 15; 197(1):171-9. PMID: 21310179; PMCID: PMC3072962.
    52. Kim S, Bergsneider M, Hu X. A systematic study of linear dynamic modeling of intracranial pressure dynamics. Physiol Meas. 2011 Mar; 32(3):319-36. PMID: 21285483; PMCID: PMC3096467.
    53. Kim S, Hu X, McArthur D, Hamilton R, Bergsneider M, Glenn T, Martin N, Vespa P. Inter-subject correlation exists between morphological metrics of cerebral blood flow velocity and intracranial pressure pulses. Neurocrit Care. 2011 Apr; 14(2):229-37. PMID: 21136207; PMCID: PMC3071636.
    54. Kim S, Scalzo F, Bergsneider M, Vespa P, Martin N, Hu X. Noninvasive intracranial pressure assessment based on a data-mining approach using a nonlinear mapping function. IEEE Trans Biomed Eng. 2012 Mar; 59(3):619-26. PMID: 21097375; PMCID: PMC3130850.
    55. Scalzo F, Asgari S, Kim S, Bergsneider M, Hu X. Robust peak recognition in intracranial pressure signals. Biomed Eng Online. 2010; 9:61. PMID: 20959014; PMCID: PMC2984490.
    56. Kasprowicz M, Asgari S, Bergsneider M, Czosnyka M, Hamilton R, Hu X. Pattern recognition of overnight intracranial pressure slow waves using morphological features of intracranial pressure pulse. J Neurosci Methods. 2010 Jul 15; 190(2):310-8. PMID: 20566403; PMCID: PMC3096461.
    57. Hu X, Xu P, Asgari S, Vespa P, Bergsneider M. Forecasting ICP elevation based on prescient changes of intracranial pressure waveform morphology. IEEE Trans Biomed Eng. 2010 May; 57(5):1070-8. PMID: 20659820; PMCID: PMC2911990.
    58. Hu X, Glenn T, Scalzo F, Bergsneider M, Sarkiss C, Martin N, Vespa P. Intracranial pressure pulse morphological features improved detection of decreased cerebral blood flow. Physiol Meas. 2010 May; 31(5):679-95. PMID: 20348611; PMCID: PMC2855777.
    59. Hu X, Xu P, Wu S, Asgari S, Bergsneider M. A data mining framework for time series estimation. J Biomed Inform. 2010 Apr; 43(2):190-9. PMID: 19900575; PMCID: PMC2839011.
    60. Asgari S, Bergsneider M, Hu X. A robust approach toward recognizing valid arterial-blood-pressure pulses. IEEE Trans Inf Technol Biomed. 2010 Jan; 14(1):166-72. PMID: 19884099; PMCID: PMC2887660.
    61. Asgari S, Xu P, Bergsneider M, Hu X. A subspace decomposition approach toward recognizing valid pulsatile signals. Physiol Meas. 2009 Nov; 30(11):1211-25. PMID: 19794232; PMCID: PMC2851740.
    62. Xu P, Kasprowicz M, Bergsneider M, Hu X. Improved noninvasive intracranial pressure assessment with nonlinear kernel regression. IEEE Trans Inf Technol Biomed. 2010 Jul; 14(4):971-8. PMID: 19643711; PMCID: PMC2900395.
    63. Sapo M, Wu S, Asgari S, McNair N, Buxey F, Martin N, Hu X. A comparison of vital signs charted by nurses with automated acquired values using waveform quality indices. J Clin Monit Comput. 2009 Oct; 23(5):263-71. PMID: 19629728.
      View in: PubMed
    64. Scalzo F, Xu P, Asgari S, Bergsneider M, Hu X. Regression analysis for peak designation in pulsatile pressure signals. Med Biol Eng Comput. 2009 Sep; 47(9):967-77. PMID: 19578916; PMCID: PMC2734262.
    65. Hu X, Subudhi AW, Xu P, Asgari S, Roach RC, Bergsneider M. Inferring cerebrovascular changes from latencies of systemic and intracranial pulses: a model-based latency subtraction algorithm. J Cereb Blood Flow Metab. 2009 Apr; 29(4):688-97. PMID: 19142194; PMCID: PMC2664398.
    66. Hamilton R, Xu P, Asgari S, Kasprowicz M, Vespa P, Bergsneider M, Hu X. Forecasting intracranial pressure elevation using pulse waveform morphology. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:4331-4. PMID: 19963821.
      View in: PubMed
    67. Hu X, Xu P, Scalzo F, Vespa P, Bergsneider M. Morphological clustering and analysis of continuous intracranial pressure. IEEE Trans Biomed Eng. 2009 Mar; 56(3):696-705. PMID: 19272879; PMCID: PMC2673331.
    68. Xu P, Tian Y, Lei X, Hu X, Yao D. Equivalent charge source model based iterative maximum neighbor weight for sparse EEG source localization. Ann Biomed Eng. 2008 Dec; 36(12):2051-67. PMID: 18830695.
      View in: PubMed
    69. Xu P, Bergsneider M, Hu X. Pulse onset detection using neighbor pulse-based signal enhancement. Med Eng Phys. 2009 Apr; 31(3):337-45. PMID: 18632299; PMCID: PMC2649996.
    70. Hu X, Xu P, Lee DJ, Vespa P, Baldwin K, Bergsneider M. An algorithm for extracting intracranial pressure latency relative to electrocardiogram R wave. Physiol Meas. 2008 Apr; 29(4):459-71. PMID: 18354246; PMCID: PMC2629794.
    71. Bergsneider M, Miller C, Vespa PM, Hu X. Surgical management of adult hydrocephalus. Neurosurgery. 2008 Feb; 62 Suppl 2:643-59; discussion 659-60. PMID: 18596440.
      View in: PubMed
    72. Hu X, Xu P, Lee DJ, Paul V, Bergsneider M. Morphological changes of intracranial pressure pulses are correlated with acute dilatation of ventricles. Acta Neurochir Suppl. 2008; 102:131-6. PMID: 19388304.
      View in: PubMed
    73. Scalzo F, Xu P, Bergsneider M, Hu X. Nonlinear regression for sub-peak detection of intracranial pressure signals. Conf Proc IEEE Eng Med Biol Soc. 2008; 2008:5411-4. PMID: 19163941.
      View in: PubMed
    74. Xu P, Scalzo F, Bergsneider M, Vespa P, Chad M, Hu X. Wavelet entropy characterization of elevated intracranial pressure. Conf Proc IEEE Eng Med Biol Soc. 2008; 2008:2924-7. PMID: 19163318.
      View in: PubMed
    75. Cattivelli FS, Sayed AH, Hu X, Lee D, Vespa P. Mathematical models of cerebral hemodynamics for detection of vasospasm in major cerebral arteries. Acta Neurochir Suppl. 2008; 102:63-9. PMID: 19388290; PMCID: PMC2673531.
    76. Hu X, Miller C, Vespa P, Bergsneider M. Adaptive computation of approximate entropy and its application in integrative analysis of irregularity of heart rate variability and intracranial pressure signals. Med Eng Phys. 2008 Jun; 30(5):631-9. PMID: 17714974; PMCID: PMC2413186.
    77. Hu X, Nenov V, Vespa P, Bergsneider M. Characterization of interdependency between intracranial pressure and heart variability signals: a causal spectral measure and a generalized synchronization measure. IEEE Trans Biomed Eng. 2007 Aug; 54(8):1407-17. PMID: 17694861; PMCID: PMC2140277.
    78. Hu X, Nenov V, Bergsneider M, Glenn TC, Vespa P, Martin N. Estimation of hidden state variables of the Intracranial system using constrained nonlinear Kalman filters. IEEE Trans Biomed Eng. 2007 Apr; 54(4):597-610. PMID: 17405367.
      View in: PubMed
    79. Vespa PM, Miller C, Hu X, Nenov V, Buxey F, Martin NA. Intensive care unit robotic telepresence facilitates rapid physician response to unstable patients and decreased cost in neurointensive care. Surg Neurol. 2007 Apr; 67(4):331-7. PMID: 17350395.
      View in: PubMed
    80. Hu X, Nenov V. A single-lead ECG enhancement algorithm using a regularized data-driven filter. IEEE Trans Biomed Eng. 2006 Feb; 53(2):347-51. PMID: 16485766.
      View in: PubMed
    81. Hu X, Nenov V, Glenn TC, Steiner LA, Czosnyka M, Bergsneider M, Martin N. Nonlinear analysis of cerebral hemodynamic and intracranial pressure signals for characterization of autoregulation. IEEE Trans Biomed Eng. 2006 Feb; 53(2):195-209. PMID: 16485748.
      View in: PubMed
    82. Hu X, Nenov V, Bergsneider M. Integrative analysis of intracranial pressure and R-R interval signals: a study of ICP B-wave using causal coherence. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:464-7. PMID: 17945587.
      View in: PubMed
    83. Hu X, Alwan AA, Rubinstein EH, Bergsneider M. Reduction of compartment compliance increases venous flow pulsatility and lowers apparent vascular compliance: implications for cerebral blood flow hemodynamics. Med Eng Phys. 2006 May; 28(4):304-14. PMID: 16112597.
      View in: PubMed
    84. Hu X, Nenov V, Bergsneider M. Phase Coordination between Intracranial Pressure and Electrocardiogram Signals. Conf Proc IEEE Eng Med Biol Soc. 2005; 1:45-8. PMID: 17282107.
      View in: PubMed
    85. Hu X, Nenov V, Vespa P, Bergsneider M. Estimation of hidden state variables of the intracranial system using constrained nonlinear Kalman filters. Conf Proc IEEE Eng Med Biol Soc. 2005; 6:5631-4. PMID: 17281533; PMCID: PMC2148030.
    86. Bergsneider M, Yang I, Hu X, McArthur DL, Cook SW, Boscardin WJ. Relationship between valve opening pressure, body position, and intracranial pressure in normal pressure hydrocephalus: paradigm for selection of programmable valve pressure setting. Neurosurgery. 2004 Oct; 55(4):851-8; discussion 858-9. PMID: 15458593.
      View in: PubMed
    87. Hu X, Nenov V. Multivariate AR modeling of electromyography for the classification of upper arm movements. Clin Neurophysiol. 2004 Jun; 115(6):1276-87. PMID: 15134694.
      View in: PubMed
    88. Hu X, Nenov V. Robust measure for characterizing generalized synchronization. Phys Rev E Stat Nonlin Soft Matter Phys. 2004 Feb; 69(2 Pt 2):026206. PMID: 14995547.
      View in: PubMed
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