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    Xu Ran, PhD

    TitlePostdoctoral Scholar
    SchoolUCSF School of Medicine
    DepartmentInstitute for Neurodegenerative Diseases
    Address675 Nelson Rising Lane
    San Francisco CA 94158
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      Collapse Biography 
      Collapse Education and Training
      University of MichiganPhDMedicinal Chemistry2015
      Shanghai Jiao Tong UniversityMSMedicinal Chemistry2009
      Shanghai Jiao Tong UniversityBSPharmacy2006

      Collapse Overview 
      Collapse Interests
      Protein chaperones, protein-protein interactions, cancer targeted therapy, medicinal chemistry, small-molecule synthesis, stapled peptides.

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Ran X, Liu L, Yang CY, Lu J, Chen Y, Lei M, Wang S. Design of High-Affinity Stapled Peptides To Target the Repressor Activator Protein 1 (RAP1)/Telomeric Repeat-Binding Factor 2 (TRF2) Protein-Protein Interaction in the Shelterin Complex. J Med Chem. 2016 Jan 14; 59(1):328-34. PMID: 26673461.
        View in: PubMed
      2. Ran X, Zhao Y, Liu L, Bai L, Yang CY, Zhou B, Meagher JL, Chinnaswamy K, Stuckey JA, Wang S. Structure-Based Design of ?-Carboline Analogues as Potent and Specific BET Bromodomain Inhibitors. J Med Chem. 2015 Jun 25; 58(12):4927-39. PMID: 26080064.
        View in: PubMed
      3. Wang, Shaomeng; Ran, Xu; Zhao, Yujun; Yang, Chao-Yie; Liu, Liu; Bai, Longchuan; Mceachern, Donna; Stuckey, Jeanne; Meagher, Jennifer Lynn; Sun, Duxin; Li, Xiaoqin; Zhou, Bing; Karatas, Hacer; Luo, Ruijuan; Chinnaiyan, Arul; Asangani, Irfan A. . Preparation of pyridoindole, pyridazinoindole and pyrimidinoindole compounds as BET bromodomain inhibitors. 2014.
      4. Kurokawa M, Kim J, Geradts J, Matsuura K, Liu L, Ran X, Xia W, Ribar TJ, Henao R, Dewhirst MW, Kim WJ, Lucas JE, Wang S, Spector NL, Kornbluth S. A network of substrates of the E3 ubiquitin ligases MDM2 and HUWE1 control apoptosis independently of p53. Sci Signal. 2013 May 7; 6(274):ra32. PMID: 23652204; PMCID: PMC3770270.
      5. Kawamoto SA, Coleska A, Ran X, Yi H, Yang CY, Wang S. Design of triazole-stapled BCL9 a-helical peptides to target the ß-catenin/B-cell CLL/lymphoma 9 (BCL9) protein-protein interaction. J Med Chem. 2012 Feb 9; 55(3):1137-46. PMID: 22196480; PMCID: PMC3286869.
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