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    Zhengshan Chen, PhD

    TitleAssistant Researcher
    SchoolUCSF School of Medicine
    DepartmentLaboratory Medicine
    Address513 Parnassus Ave, Med Sci
    San Francisco CA 94143
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      Collapse Biography 
      Collapse Education and Training
      Peking University Health Science CenterPhDDepartment of Pathology2009
      Peking University Health Science CenterMD Department of Medicine2004

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Titz B, Graeber TG, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Willman CL, Melnick A, Loh ML, Jung JU, Coligan JE, Bolland S, Mak TW, Limnander A, Jumaa H, Reth M, Weiss A, Lowell CA, Müschen M. Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature. 2015 May 21; 521(7552):357-61. PMID: 25799995; PMCID: PMC4441554 [Available on 11/21/15].
      2. Geng H, Hurtz C, Lenz KB, Chen Z, Baumjohann D, Thompson S, Goloviznina NA, Chen WY, Huan J, LaTocha D, Ballabio E, Xiao G, Lee JW, Deucher A, Qi Z, Park E, Huang C, Nahar R, Kweon SM, Shojaee S, Chan LN, Yu J, Kornblau SM, Bijl JJ, Ye BH, Mark Ansel K, Paietta E, Melnick A, Hunger SP, Kurre P, Tyner JW, Loh ML, Roeder RG, Druker BJ, Burger JA, Milne TA, Chang BH, Müschen M. Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia. Cancer Cell. 2015 Mar 9; 27(3):409-25. PMID: 25759025; PMCID: PMC4618684 [Available on 03/09/16].
      3. Buchner M, Swaminathan S, Chen Z, Müschen M. Mechanisms of pre-B-cell receptor checkpoint control and its oncogenic subversion in acute lymphoblastic leukemia. Immunol Rev. 2015 Jan; 263(1):192-209. PMID: 25510278.
        View in: PubMed
      4. Gu J, Lei Y, Huang Y, Zhao Y, Li J, Huang T, Zhang J, Wang J, Deng X, Chen Z, Korteweg C, Deng R, Yan M, Xu Q, Dong S, Cai M, Luo L, Huang G, Wang Y, Li Q, Lin C, Su M, Yang C, Zhuang Z. Fab fragment glycosylated IgG may play a central role in placental immune evasion. Hum Reprod. 2015 Feb; 30(2):380-91. PMID: 25505012; PMCID: PMC4303772 [Available on 02/01/16].
      5. Li J, Korteweg C, Qiu Y, Luo J, Chen Z, Huang G, Li W, Gu J. Two ultrastructural distribution patterns of immunoglobulin G in human placenta and functional implications. Biol Reprod. 2014 Nov; 91(5):128. PMID: 25273527.
        View in: PubMed
      6. Lei Y, Huang T, Su M, Luo J, Korteweg C, Li J, Chen Z, Qiu Y, Liu X, Yan M, Wang Y, Gu J. Expression and distribution of immunoglobulin G in the normal liver, hepatocarcinoma and postpartial hepatectomy liver. Lab Invest. 2014 Nov; 94(11):1283-95. PMID: 25264708.
        View in: PubMed
      7. Swaminathan S, Huang C, Geng H, Chen Z, Harvey R, Kang H, Ng C, Titz B, Hurtz C, Sadiyah MF, Nowak D, Thoennissen GB, Rand V, Graeber TG, Koeffler HP, Carroll WL, Willman CL, Hall AG, Igarashi K, Melnick A, Müschen M. BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint. Nat Med. 2013 Aug; 19(8):1014-22. PMID: 23852341; PMCID: PMC3954721.
      8. Yang B, Ma C, Chen Z, Yi W, McNutt MA, Wang Y, Korteweg C, Gu J. Correlation of immunoglobulin G expression and histological subtype and stage in breast cancer. PLoS One. 2013; 8(3):e58706. PMID: 23554916; PMCID: PMC3595271.
      9. Ma C, Wang Y, Zhang G, Chen Z, Qiu Y, Li J, Luo J, Huang B, Jiang C, Huang G, Wan X, Korteweg C, Gu J. Immunoglobulin G expression and its potential role in primary and metastatic breast cancers. Curr Mol Med. 2013 Mar; 13(3):429-37. PMID: 23331015.
        View in: PubMed
      10. Ramezani-Rad P, Geng H, Hurtz C, Chan LN, Chen Z, Jumaa H, Melnick A, Paietta E, Carroll WL, Willman CL, Lefebvre V, Müschen M. SOX4 enables oncogenic survival signals in acute lymphoblastic leukemia. Blood. 2013 Jan 3; 121(1):148-55. PMID: 23152540; PMCID: PMC3538327.
      11. Niu N, Zhang J, Huang T, Sun Y, Chen Z, Yi W, Korteweg C, Wang J, Gu J. IgG expression in human colorectal cancer and its relationship to cancer cell behaviors. PLoS One. 2012; 7(11):e47362. PMID: 23133595; PMCID: PMC3486799.
      12. Qiu Y, Korteweg C, Chen Z, Li J, Luo J, Huang G, Gu J. Immunoglobulin G expression and its colocalization with complement proteins in papillary thyroid cancer. Mod Pathol. 2012 Jan; 25(1):36-45. PMID: 21909078.
        View in: PubMed
      13. Liu Y, Chen Z, Niu N, Chang Q, Deng R, Korteweg C, Gu J. IgG gene expression and its possible significance in prostate cancers. Prostate. 2012 May 1; 72(6):690-701. PMID: 22430367.
        View in: PubMed
      14. Zhang L, Hu S, Korteweg C, Chen Z, Qiu Y, Su M, Gu J. Expression of immunoglobulin G in esophageal squamous cell carcinomas and its association with tumor grade and Ki67. Hum Pathol. 2012 Mar; 43(3):423-34. PMID: 21855109.
        View in: PubMed
      15. Chen Z, Li J, Xiao Y, Zhang J, Zhao Y, Liu Y, Ma C, Qiu Y, Luo J, Huang G, Korteweg C, Gu J. Immunoglobulin G locus events in soft tissue sarcoma cell lines. PLoS One. 2011; 6(6):e21276. PMID: 21731691; PMCID: PMC3121753.
      16. Chen Z, Xiao Y, Zhang J, Li J, Liu Y, Zhao Y, Ma C, Luo J, Qiu Y, Huang G, Korteweg C, Gu J. Transcription factors E2A, FOXO1 and FOXP1 regulate recombination activating gene expression in cancer cells. PLoS One. 2011; 6(5):e20475. PMID: 21655267; PMCID: PMC3105062.
      17. Zhao Y, Liu Y, Chen Z, Korteweg C, Gu J. Immunoglobulin g (IgG) expression in human umbilical cord endothelial cells. J Histochem Cytochem. 2011 May; 59(5):474-88. PMID: 21430258; PMCID: PMC3201178.
      18. Chen Z, Huang X, Ye J, Pan P, Cao Q, Yang B, Li Z, Su M, Huang C, Gu J. Immunoglobulin G is present in a wide variety of soft tissue tumors and correlates well with proliferation markers and tumor grades. Cancer. 2010 Apr 15; 116(8):1953-63. PMID: 20186824.
        View in: PubMed
      19. Chen Z, Qiu X, Gu J. Immunoglobulin expression in non-lymphoid lineage and neoplastic cells. Am J Pathol. 2009 Apr; 174(4):1139-48. PMID: 19246641; PMCID: PMC2671347.
      20. Reynaud D, Demarco IA, Reddy KL, Schjerven H, Bertolino E, Chen Z, Smale ST, Winandy S, Singh H. Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros. Nat Immunol. 2008 Aug; 9(8):927-36. PMID: 18568028; PMCID: PMC2699484.
      21. Cao Q, Yu C, Xue R, Hsueh W, Pan P, Chen Z, Wang S, McNutt M, Gu J. Autophagy induced by suberoylanilide hydroxamic acid in Hela S3 cells involves inhibition of protein kinase B and up-regulation of Beclin 1. Int J Biochem Cell Biol. 2008; 40(2):272-83. PMID: 17881280.
        View in: PubMed
      22. Chen Z, Gu J. Immunoglobulin G expression in carcinomas and cancer cell lines. FASEB J. 2007 Sep; 21(11):2931-8. PMID: 17475920.
        View in: PubMed
      23. Chang Q, Chen Z, You J, McNutt MA, Zhang T, Han Z, Zhang X, Gong E, Gu J. All-trans-retinoic acid induces cell growth arrest in a human medulloblastoma cell line. J Neurooncol. 2007 Sep; 84(3):263-7. PMID: 17453147.
        View in: PubMed
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