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Rapid biphasic decay of intact and defective HIV DNA reservoir during acute treated HIV disease. Nat Commun. 2024 Nov 18; 15(1):9966.
Barbehenn A, Shi L, Shao J, Hoh R, Hartig HM, Pae V, Sarvadhavabhatla S, Donaire S, Sheikhzadeh C, Milush J, Laird GM, Mathias M, Ritter K, Peluso MJ, Martin J, Hecht F, Pilcher C, Cohen SE, Buchbinder S, Havlir D, Gandhi M, Henrich TJ, Hatano H, Wang J, Deeks SG, Lee SA. PMID: 39557853; PMCID: PMC11574060.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Infection-associated chronic conditions: Why Long Covid is our best chance to untangle Osler's web. Sci Transl Med. 2024 Nov 13; 16(773):eado2101.
Peluso MJ, Hanson MR, Deeks SG. PMID: 39536121.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Early Viral Dynamics Predict HIV Post-Treatment Control After Analytic Treatment Interruption. J Infect Dis. 2024 Nov 08.
Magombedze G, Vendrame E, SenGupta D, Geleziunas R, Little S, Smith D, Walker B, Routy JP, Hecht FM, Chun TW, Sneller M, Li JZ, Deeks SG, Peluso MJ. PMID: 39513745.
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PubMed Mentions: Fields:
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Measurement of circulating viral antigens post-SARS-CoV-2 infection in a multicohort study. Clin Microbiol Infect. 2024 Sep 27.
Swank Z, Borberg E, Chen Y, Senussi Y, Chalise S, Manickas-Hill Z, Yu XG, Li JZ, Alter G, Henrich TJ, Kelly JD, Hoh R, Goldberg SA, Deeks SG, Martin JN, Peluso MJ, Talla A, Li X, Skene P, Bumol TF, Torgerson TR, Czartoski JL, McElrath MJ, Karlson EW, Walt DR, RECOVER consortium authors. PMID: 39389851.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Mechanisms of long COVID and the path toward therapeutics. Cell. 2024 Oct 03; 187(20):5500-5529.
Peluso MJ, Deeks SG. PMID: 39326415.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Sirolimus reduces T cell cycling, immune checkpoint marker expression, and HIV-1 DNA in people with HIV. Cell Rep Med. 2024 Oct 15; 5(10):101745.
Henrich TJ, Bosch RJ, Godfrey C, Mar H, Nair A, Keefer M, Fichtenbaum C, Moisi D, Clagett B, Buck AM, Deitchman AN, Aweeka F, Li JZ, Kuritzkes DR, Lederman MM, Hsue PY, Deeks SG, ACTG A5337 Team. PMID: 39321793.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Recall and Appraisal of the Risks, Benefits, and Objectives of Interrupting HIV Treatment in an HIV Cure-Related Study. AIDS Behav. 2024 Sep 17.
Korolkova A, Ndukwe SO, Dee L, Deeks SG, Peluso MJ, Hoh R, Rodriguez A, Sugarman J, Rodriguez Garcia L, Dubé K, Sauceda JA. PMID: 39287733.
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PubMed Mentions: Fields:
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A Pooled Analysis of Eight Clinical Studies Suggests a Link Between Influenza-Like Symptoms and Pharmacodynamics of the Toll-Like Receptor-7 Agonist Vesatolimod. Infect Dis Ther. 2024 Nov; 13(11):2285-2299.
Riddler SA, Benson CA, Brinson C, Deeks SG, DeJesus E, Mills A, Para MF, Ramgopal MN, Cai Y, Zheng Y, Zhang L, Jiang W, Liu X, Verrill D, Lim D, de Vries CR, Wallin JJ, Vendrame E, SenGupta D. PMID: 39278975; PMCID: PMC11499514.
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PubMed Mentions:
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Integrated epigenomic exposure signature discovery. Epigenomics. 2024; 16(14):1013-1029.
Schuetter J, Minard-Smith A, Hill B, Beare JL, Vornholt A, Burke TW, Murugan V, Smith AK, Chandrasekaran T, Shamma HJ, Kahaian SC, Fillinger KL, Amper MAS, Cheng WS, Ge Y, George MC, Guevara K, Lovette-Okwara N, Mahajan A, Marjanovic N, Mendelev N, Fowler VG, McClain MT, Miller CM, Mofsowitz S, Nair VD, Nudelman G, Evans TG, Castellino F, Ramos I, Rirak S, Ruf-Zamojski F, Seenarine N, Soares-Shanoski A, Vangeti S, Vasoya M, Yu X, Zaslavsky E, Ndhlovu LC, Corley MJ, Bowler S, Deeks SG, Letizia AG, Sealfon SC, Woods CW, Spurbeck RR. PMID: 39225561; PMCID: PMC11404615.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Early biological markers of post-acute sequelae of SARS-CoV-2 infection. Nat Commun. 2024 Aug 29; 15(1):7466.
Lu S, Peluso MJ, Glidden DV, Davidson MC, Lugtu K, Pineda-Ramirez J, Tassetto M, Garcia-Knight M, Zhang A, Goldberg SA, Chen JY, Fortes-Cobby M, Park S, Martinez A, So M, Donovan A, Viswanathan B, Hoh R, Donohue K, McIlwain DR, Gaudiliere B, Anglin K, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Deeks SG, Briggs-Hagen M, Andino R, Midgley CM, Martin JN, Saydah S, Kelly JD. PMID: 39198441; PMCID: PMC11358427.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Galectin-9 Levels as a Potential Predictor of Intact HIV Reservoir Decay. J Infect Dis. 2024 Aug 28.
Serrano-Villar S, Gala A, Bacchetti P, Hoh R, di Germanio C, Cohn LB, Henrich TJ, Hunt PW, Laird GM, Pillai SK, Deeks SG, Peluso MJ. PMID: 39207259.
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PubMed Mentions: Fields:
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HIV-1 control in vivo is related to the number but not the fraction of infected cells with viral unspliced RNA. Proc Natl Acad Sci U S A. 2024 Sep 03; 121(36):e2405210121.
Capoferri AA, Wiegand A, Hong F, Jacobs JL, Spindler J, Musick A, Bale MJ, Shao W, Sobolewski MD, Cillo AR, Luke BT, Fennessey CM, Gorelick RJ, Hoh R, Halvas EK, Deeks SG, Coffin JM, Mellors JW, Kearney MF. PMID: 39190360; PMCID: PMC11388345.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Rapid Biphasic Decay of Intact and Defective HIV DNA Reservoir During Acute Treated HIV Disease. medRxiv. 2024 Aug 22.
Barbehenn A, Shi L, Shao J, Hoh R, Hartig HM, Pae V, Sarvadhavabhatla S, Donaire S, Sheikhzadeh C, Milush J, Laird GM, Mathias M, Ritter K, Peluso MJ, Martin J, Hecht F, Pilcher C, Cohen SE, Buchbinder S, Havlir D, Gandhi M, Henrich TJ, Hatano H, Wang J, Deeks SG, Lee SA. PMID: 38585951; PMCID: PMC10996734.
View in:
PubMed Mentions:
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Mechanisms and efficacy of small molecule latency-promoting agents to inhibit HIV reactivation ex vivo. JCI Insight. 2024 Aug 20; 9(19).
Janssens J, Kim P, Kim SJ, Wedrychowski A, Kadiyala GN, Hunt PW, Deeks SG, Wong JK, Yukl SA. PMID: 39163135; PMCID: PMC11466185.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Brief Report: Low-Dose Methotrexate Does Not Affect Measures of HIV-1 Persistence in Individuals With Chronically Treated HIV-1 Infection. J Acquir Immune Defic Syndr. 2024 Aug 15; 96(5):481-485.
Cyktor JC, Yeh E, Ribaudo H, Hoeth D, Naqvi A, Bell T, Ridker PM, Fichtenbaum C, Daar ES, Havlir D, Tawakol A, Lederman MM, Stein JH, Deeks SG, Currier JS, Hsue PY, Mellors JW, A5314 Team. PMID: 39287554; PMCID: PMC11408752.
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PubMed Mentions: Fields:
Translation:
HumansCellsCTClinical Trials
-
Prediction of differential Gag versus Env responses to a mosaic HIV-1 vaccine regimen by HLA class I alleles. J Virol. 2024 Aug 20; 98(8):e0028124.
Nelson GW, van Duijn J, Yuki Y, Pau MG, Tomaka F, Lavreys L, DeRosa SC, McElrath MJ, Kirk GD, Michael NL, Haas DW, Deeks SG, Wolinsky S, Walker B, Barouch DH, Stieh D, Carrington M. PMID: 39046263; PMCID: PMC11338073.
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PubMed Mentions: Fields:
Translation:
HumansCellsCTClinical Trials
-
Tissue-based T cell activation and viral RNA persist for up to 2 years after SARS-CoV-2 infection. Sci Transl Med. 2024 Jul 03; 16(754):eadk3295.
Peluso MJ, Ryder D, Flavell RR, Wang Y, Levi J, LaFranchi BH, Deveau TM, Buck AM, Munter SE, Asare KA, Aslam M, Koch W, Szabo G, Hoh R, Deswal M, Rodriguez AE, Buitrago M, Tai V, Shrestha U, Lu S, Goldberg SA, Dalhuisen T, Vasquez JJ, Durstenfeld MS, Hsue PY, Kelly JD, Kumar N, Martin JN, Gambhir A, Somsouk M, Seo Y, Deeks SG, Laszik ZG, VanBrocklin HF, Henrich TJ. PMID: 38959327; PMCID: PMC11337933.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Circulating immune and plasma biomarkers of time to HIV rebound in HIV controllers treated with vesatolimod. Front Immunol. 2024; 15:1405348.
Abdel-Mohsen M, Deeks S, Giron L, Hong KY, Goldman A, Zhang L, Huang SSY, Verrill D, Guo S, Selzer L, de Vries CR, Vendrame E, SenGupta D, Wallin JJ, Cai Y. PMID: 38979421; PMCID: PMC11229794.
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PubMed Mentions: Fields:
Translation:
HumansCellsCTClinical Trials
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HIV rebound in HIV controllers is associated with a specific fecal microbiome profile. Eur J Immunol. 2024 Aug; 54(8):e2350809.
Cai Y, Podlaha O, Deeks SG, Brinson C, Ramgopal MN, DeJesus E, Mills A, Shalit P, Abdel-Mohsen M, Zhang L, de Vries CR, Vendrame E, SenGupta D, Wallin JJ. PMID: 38727191.
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Translation:
HumansCells
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AMPLON: Amplifying DNA with Multiarm Priming and Looping Optimization of Nucleic Acid. Adv Mater. 2024 Jul; 36(28):e2311634.
Doganay MT, Roman E, Hujer AM, Bonomo RA, Deeks SG, Kuritzkes DR, Draz MS. PMID: 38657970; PMCID: PMC11239297.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Autologous neutralizing antibody responses after antiretroviral therapy in acute and early HIV-1. J Clin Invest. 2024 Apr 23; 134(11).
Whitehill GD, Joy J, Marino FE, Krause R, Mallick S, Courtney H, Park K, Carey J, Hoh R, Hartig H, Pae V, Sarvadhavabhatla S, Donaire S, Deeks SG, Lynch RM, Lee SA, Bar KJ. PMID: 38652564; PMCID: PMC11142743.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCellsCTClinical Trials
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Differential susceptibility of cells infected with defective and intact HIV proviruses to killing by obatoclax and other small molecules. AIDS. 2024 07 15; 38(9):1281-1291.
Kadiyala GN, Telwatte S, Wedrychowski A, Janssens J, Kim SJ, Kim P, Deeks S, Wong JK, Yukl SA. PMID: 38626436; PMCID: PMC11216394.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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High-parameter phenotypic characterization reveals a subset of human Th17 cells that preferentially produce IL-17 against M. tuberculosis antigen. Front Immunol. 2024; 15:1378040.
Ogongo P, Tran A, Marzan F, Gingrich D, Krone M, Aweeka F, Lindestam Arlehamn CS, Martin JN, Deeks SG, Hunt PW, Ernst JD. PMID: 38698866; PMCID: PMC11064812.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
-
Long COVID and post-acute sequelae of SARS-CoV-2 pathogenesis and treatment: A Keystone Symposia report. Ann N Y Acad Sci. 2024 May; 1535(1):31-41.
Durstenfeld MS, Weiman S, Holtzman M, Blish C, Pretorius R, Deeks SG. PMID: 38593220.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Plasma-based antigen persistence in the post-acute phase of COVID-19. Lancet Infect Dis. 2024 Jun; 24(6):e345-e347.
Peluso MJ, Swank ZN, Goldberg SA, Lu S, Dalhuisen T, Borberg E, Senussi Y, Luna MA, Chang Song C, Clark A, Zamora A, Lew M, Viswanathan B, Huang B, Anglin K, Hoh R, Hsue PY, Durstenfeld MS, Spinelli MA, Glidden DV, Henrich TJ, Kelly JD, Deeks SG, Walt DR, Martin JN. PMID: 38604216.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
-
Author Correction: Exploring synergies between B- and T-cell vaccine approaches to optimize immune responses against HIV-workshop report. NPJ Vaccines. 2024 Mar 14; 9(1):61.
Maciel M, Amara RR, Bar KJ, Crotty S, Deeks SG, Duplessis C, Gaiha G, McElrath MJ, McMichael A, Palin A, Rutishauser R, Shapiro S, Smiley ST, D'Souza MP. PMID: 38485736; PMCID: PMC10940590.
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PubMed Mentions:
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Advancing HIV cure research in low- and middle-income countries requires empowerment of the next generation of scientists. J Virus Erad. 2024 Mar; 10(1):100364.
Tatoud R, Jones RB, Dong K, Ndung'u T, Deeks S, Tiemessen CT. PMID: 38559321; PMCID: PMC10979089.
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PubMed Mentions:
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High-parameter phenotypic characterization reveals a subset of human Th17 cells that preferentially produce IL17 against M. tuberculosis antigen. bioRxiv. 2024 Mar 06.
Ogongo P, Tran A, Marzan F, Gingrich D, Krone M, Aweeka F, Lindestam Arlehamn CS, Martin JN, Deeks SG, Hunt PW, Ernst JD. PMID: 36711855; PMCID: PMC9881994.
View in:
PubMed Mentions:
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Exploring synergies between B- and T-cell vaccine approaches to optimize immune responses against HIV-workshop report. NPJ Vaccines. 2024 Feb 21; 9(1):39.
Maciel M, Amara RR, Bar KJ, Crotty S, Deeks SG, Duplessis C, Gaiha G, McElrath MJ, McMichael A, Palin A, Rutishauser R, Shapiro S, Smiley ST, D'Souza MP. PMID: 38383616; PMCID: PMC10881492.
View in:
PubMed Mentions:
2
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Mild HIV-specific selective forces overlaying natural CD4+ T cell dynamics explain the clonality and decay dynamics of HIV reservoir cells. medRxiv. 2024 Feb 15.
Reeves DB, Rigau DN, Romero A, Zhang H, Simonetti FR, Varriale J, Hoh R, Zhang L, Smith KN, Montaner LJ, Rubin LH, Gange SJ, Roan NR, Tien PC, Margolick JB, Peluso MJ, Deeks SG, Schiffer JT, Siliciano JD, Siliciano RF, Antar AAR. PMID: 38405967; PMCID: PMC10888981.
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PubMed Mentions:
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Predictors of HIV rebound differ by timing of antiretroviral therapy initiation. JCI Insight. 2024 Feb 08; 9(3).
Li JZ, Melberg M, Kittilson A, Abdel-Mohsen M, Li Y, Aga E, Bosch RJ, Wonderlich ER, Kinslow J, Giron LB, Di Germanio C, Pilkinton M, MacLaren L, Keefer M, Fox L, Barr L, Acosta E, Ananworanich J, Coombs R, Mellors J, Deeks S, Gandhi RT, Busch M, Landay A, Macatangay B, Smith DM, AIDS Clinical Trials Group A5345 Study Team. PMID: 38329130; PMCID: PMC10967395.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Bispecific antibodies promote natural killer cell-mediated elimination of HIV-1 reservoir cells. Nat Immunol. 2024 Mar; 25(3):462-470.
Board NL, Yuan Z, Wu F, Moskovljevic M, Ravi M, Sengupta S, Mun SS, Simonetti FR, Lai J, Tebas P, Lynn K, Hoh R, Deeks SG, Siliciano JD, Montaner LJ, Siliciano RF. PMID: 38278966; PMCID: PMC10907297.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Impact of HLA class I functional divergence on HIV control. Science. 2024 01 19; 383(6680):319-325.
Viard M, O'hUigin C, Yuki Y, Bashirova AA, Collins DR, Urbach JM, Wolinsky S, Buchbinder S, Kirk GD, Goedert JJ, Michael NL, Haas DW, Deeks SG, Walker BD, Yu X, Carrington M. PMID: 38236978; PMCID: PMC11395297.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2. Nat Immunol. 2024 Feb; 25(2):218-225.
Yin K, Peluso MJ, Luo X, Thomas R, Shin MG, Neidleman J, Andrew A, Young KC, Ma T, Hoh R, Anglin K, Huang B, Argueta U, Lopez M, Valdivieso D, Asare K, Deveau TM, Munter SE, Ibrahim R, Ständker L, Lu S, Goldberg SA, Lee SA, Lynch KL, Kelly JD, Martin JN, Münch J, Deeks SG, Henrich TJ, Roan NR. PMID: 38212464; PMCID: PMC10834368.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansCells
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Association of nirmatrelvir for acute SARS-CoV-2 infection with subsequent Long COVID symptoms in an observational cohort study. J Med Virol. 2024 01; 96(1):e29333.
Durstenfeld MS, Peluso MJ, Lin F, Peyser ND, Isasi C, Carton TW, Henrich TJ, Deeks SG, Olgin JE, Pletcher MJ, Beatty AL, Marcus GM, Hsue PY. PMID: 38175151; PMCID: PMC10786003.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Plasma-based antigen persistence in the post-acute phase of SARS-CoV-2 infection. medRxiv. 2023 Dec 29.
Peluso MJ, Swank ZN, Goldberg SA, Lu S, Dalhuisen T, Borberg E, Senussi Y, Luna MA, Song CC, Clark A, Zamora A, Lew M, Viswanathan B, Huang B, Anglin K, Hoh R, Hsue PY, Durstenfeld MS, Spinelli MA, Glidden DV, Henrich TJ, Daniel Kelly J, Deeks SG, Walt DR, Martin JN. PMID: 37961239; PMCID: PMC10635183.
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PubMed Mentions:
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A cohort-based study of host gene expression: tumor suppressor and innate immune/inflammatory pathways associated with the HIV reservoir size. PLoS Pathog. 2023 Nov; 19(11):e1011114.
Dwivedi AK, Gornalusse GG, Siegel DA, Barbehenn A, Thanh C, Hoh R, Hobbs KS, Pan T, Gibson EA, Martin J, Hecht F, Pilcher C, Milush J, Busch MP, Stone M, Huang ML, Reppetti J, Vo PM, Levy CN, Roychoudhury P, Jerome KR, Hladik F, Henrich TJ, Deeks SG, Lee SA. PMID: 38019897; PMCID: PMC10712869.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Viral and host mediators of non-suppressible HIV-1 viremia. Nat Med. 2023 Dec; 29(12):3212-3223.
Mohammadi A, Etemad B, Zhang X, Li Y, Bedwell GJ, Sharaf R, Kittilson A, Melberg M, Crain CR, Traunbauer AK, Wong C, Fajnzylber J, Worrall DP, Rosenthal A, Jordan H, Jilg N, Kaseke C, Giguel F, Lian X, Deo R, Gillespie E, Chishti R, Abrha S, Adams T, Siagian A, Dorazio D, Anderson PL, Deeks SG, Lederman MM, Yawetz S, Kuritzkes DR, Lichterfeld MD, Sieg S, Tsibris A, Carrington M, Brumme ZL, Castillo-Mancilla JR, Engelman AN, Gaiha GD, Li JZ. PMID: 37957382; PMCID: PMC10719098.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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The breadth of the neutralizing antibody response to original SARS-CoV-2 infection is linked to the presence of Long COVID symptoms. J Med Virol. 2023 11; 95(11):e29216.
Buck AM, Deitchman AN, Takahashi S, Lu S, Goldberg SA, Bodansky A, Kung A, Hoh R, Williams MC, Kerbleski M, Maison DP, Deveau TM, Munter SE, Lombardo J, Wrin T, Petropoulos CJ, Durstenfeld MS, Hsue PY, Kelly JD, Greenhouse B, Martin JN, Deeks SG, Peluso MJ, Henrich TJ. PMID: 37988251; PMCID: PMC10754238.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCellsPHPublic Health
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The hypoxia-regulated ectonucleotidase CD73 is a host determinant of HIV latency. Cell Rep. 2023 11 28; 42(11):113285.
Sperber HS, Raymond KA, Bouzidi MS, Ma T, Valdebenito S, Eugenin EA, Roan NR, Deeks SG, Winning S, Fandrey J, Schwarzer R, Pillai SK. PMID: 37910505; PMCID: PMC10838153.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Serotonin reduction in post-acute sequelae of viral infection. Cell. 2023 10 26; 186(22):4851-4867.e20.
Wong AC, Devason AS, Umana IC, Cox TO, Dohnalová L, Litichevskiy L, Perla J, Lundgren P, Etwebi Z, Izzo LT, Kim J, Tetlak M, Descamps HC, Park SL, Wisser S, McKnight AD, Pardy RD, Kim J, Blank N, Patel S, Thum K, Mason S, Beltra JC, Michieletto MF, Ngiow SF, Miller BM, Liou MJ, Madhu B, Dmitrieva-Posocco O, Huber AS, Hewins P, Petucci C, Chu CP, Baraniecki-Zwil G, Giron LB, Baxter AE, Greenplate AR, Kearns C, Montone K, Litzky LA, Feldman M, Henao-Mejia J, Striepen B, Ramage H, Jurado KA, Wellen KE, O'Doherty U, Abdel-Mohsen M, Landay AL, Keshavarzian A, Henrich TJ, Deeks SG, Peluso MJ, Meyer NJ, Wherry EJ, Abramoff BA, Cherry S, Thaiss CA, Levy M. PMID: 37848036; PMCID: PMC11227373.
View in:
PubMed Mentions:
71 Fields:
Translation:
Humans
-
Association of SARS-CoV-2 Infection and Cardiopulmonary Long COVID With Exercise Capacity and Chronotropic Incompetence Among People With HIV. J Am Heart Assoc. 2023 10 17; 12(20):e030896.
Durstenfeld MS, Peluso MJ, Spinelli MA, Li D, Hoh R, Chenna A, Yee B, Winslow J, Petropoulos C, Gandhi M, Henrich TJ, Aras MA, Long CS, Deeks SG, Hsue PY. PMID: 37830367; PMCID: PMC10757521.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
-
Estimating the contribution of CD4 T cell subset proliferation and differentiation to HIV persistence. Nat Commun. 2023 10 02; 14(1):6145.
Reeves DB, Bacchus-Souffan C, Fitch M, Abdel-Mohsen M, Hoh R, Ahn H, Stone M, Hecht F, Martin J, Deeks SG, Hellerstein MK, McCune JM, Schiffer JT, Hunt PW. PMID: 37783718; PMCID: PMC10545742.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Author Correction: SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC). Nat Immunol. 2023 Oct; 24(10):1778.
Proal AD, VanElzakker MB, Aleman S, Bach K, Boribong BP, Buggert M, Cherry S, Chertow DS, Davies HE, Dupont CL, Deeks SG, Eimer W, Ely EW, Fasano A, Freire M, Geng LN, Griffin DE, Henrich TJ, Iwasaki A, Izquierdo-Garcia D, Locci M, Mehandru S, Painter MM, Peluso MJ, Pretorius E, Price DA, Putrino D, Scheuermann RH, Tan GS, Tanzi RE, VanBrocklin HF, Yonker LM, Wherry EJ. PMID: 37723351.
View in:
PubMed Mentions:
1 Fields:
-
Comprehensive synergy mapping links a BAF- and NSL-containing "supercomplex" to the transcriptional silencing of HIV-1. Cell Rep. 2023 Sep 26; 42(9):113055.
Li Z, Deeks SG, Ott M, Greene WC. PMID: 37682714; PMCID: PMC10591912.
View in:
PubMed Mentions: Fields:
-
SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC). Nat Immunol. 2023 10; 24(10):1616-1627.
Proal AD, VanElzakker MB, Aleman S, Bach K, Boribong BP, Buggert M, Cherry S, Chertow DS, Davies HE, Dupont CL, Deeks SG, Eimer W, Ely EW, Fasano A, Freire M, Geng LN, Griffin DE, Henrich TJ, Iwasaki A, Izquierdo-Garcia D, Locci M, Mehandru S, Painter MM, Peluso MJ, Pretorius E, Price DA, Putrino D, Scheuermann RH, Tan GS, Tanzi RE, VanBrocklin HF, Yonker LM, Wherry EJ. PMID: 37667052.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansCells
-
SARS-CoV-2 Serology Across Scales: A Framework for Unbiased Estimation of Cumulative Incidence Incorporating Antibody Kinetics and Epidemic Recency. Am J Epidemiol. 2023 09 01; 192(9):1562-1575.
Takahashi S, Peluso MJ, Hakim J, Turcios K, Janson O, Routledge I, Busch MP, Hoh R, Tai V, Kelly JD, Martin JN, Deeks SG, Henrich TJ, Greenhouse B, Rodríguez-Barraquer I. PMID: 37119030; PMCID: PMC10472487.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
The latent reservoir of inducible, infectious HIV-1 does not decrease despite decades of antiretroviral therapy. J Clin Invest. 2023 09 01; 133(17).
McMyn NF, Varriale J, Fray EJ, Zitzmann C, MacLeod H, Lai J, Singhal A, Moskovljevic M, Garcia MA, Lopez BM, Hariharan V, Rhodehouse K, Lynn K, Tebas P, Mounzer K, Montaner LJ, Benko E, Kovacs C, Hoh R, Simonetti FR, Laird GM, Deeks SG, Ribeiro RM, Perelson AS, Siliciano RF, Siliciano JM. PMID: 37463049; PMCID: PMC10471168.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Reduced Exercise Capacity, Chronotropic Incompetence, and Early Systemic Inflammation in Cardiopulmonary Phenotype Long Coronavirus Disease 2019. J Infect Dis. 2023 08 31; 228(5):542-554.
Durstenfeld MS, Peluso MJ, Kaveti P, Hill C, Li D, Sander E, Swaminathan S, Arechiga VM, Lu S, Goldberg SA, Hoh R, Chenna A, Yee BC, Winslow JW, Petropoulos CJ, Kelly JD, Glidden DV, Henrich TJ, Martin JN, Lee YJ, Aras MA, Long CS, Grandis DJ, Deeks SG, Hsue PY. PMID: 37166076; PMCID: PMC10686699.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Long COVID manifests with T cell dysregulation, inflammation, and an uncoordinated adaptive immune response to SARS-CoV-2. bioRxiv. 2023 Aug 04.
Yin K, Peluso MJ, Luo X, Thomas R, Shin MG, Neidleman J, Andrew A, Young K, Ma T, Hoh R, Anglin K, Huang B, Argueta U, Lopez M, Valdivieso D, Asare K, Deveau TM, Munter SE, Ibrahim R, Ständker L, Lu S, Goldberg SA, Lee SA, Lynch KL, Kelly JD, Martin JN, Münch J, Deeks SG, Henrich TJ, Roan NR. PMID: 36798286; PMCID: PMC9934605.
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PubMed Mentions:
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Multimodal Molecular Imaging Reveals Tissue-Based T Cell Activation and Viral RNA Persistence for Up to 2 Years Following COVID-19. medRxiv. 2023 Jul 31.
Peluso MJ, Ryder D, Flavell R, Wang Y, Levi J, LaFranchi BH, Deveau TM, Buck AM, Munter SE, Asare KA, Aslam M, Koch W, Szabo G, Hoh R, Deswal M, Rodriguez A, Buitrago M, Tai V, Shrestha U, Lu S, Goldberg SA, Dalhuisen T, Durstenfeld MS, Hsue PY, Kelly JD, Kumar N, Martin JN, Gambir A, Somsouk M, Seo Y, Deeks SG, Laszik ZG, VanBrocklin HF, Henrich TJ. PMID: 37577714; PMCID: PMC10418298.
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PubMed Mentions:
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Adaptation of Droplet Digital PCR-Based HIV Transcription Profiling to Digital PCR and Association of HIV Transcription and Total or Intact HIV DNA. Viruses. 2023 07 22; 15(7).
Tumpach C, Rhodes A, Kim Y, Ong J, Liu H, Chibo D, Druce J, Williamson D, Hoh R, Deeks SG, Yukl SA, Roche M, Lewin SR, Telwatte S. PMID: 37515292; PMCID: PMC10384802.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection. Nature. 2023 Aug; 620(7972):128-136.
Augusto DG, Murdolo LD, Chatzileontiadou DSM, Sabatino JJ, Yusufali T, Peyser ND, Butcher X, Kizer K, Guthrie K, Murray VW, Pae V, Sarvadhavabhatla S, Beltran F, Gill GS, Lynch KL, Yun C, Maguire CT, Peluso MJ, Hoh R, Henrich TJ, Deeks SG, Davidson M, Lu S, Goldberg SA, Kelly JD, Martin JN, Vierra-Green CA, Spellman SR, Langton DJ, Dewar-Oldis MJ, Smith C, Barnard PJ, Lee S, Marcus GM, Olgin JE, Pletcher MJ, Maiers M, Gras S, Hollenbach JA. PMID: 37468623; PMCID: PMC10396966.
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PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Impact of misclassified defective proviruses on HIV reservoir measurements. Nat Commun. 2023 07 13; 14(1):4186.
Reeves DB, Gaebler C, Oliveira TY, Peluso MJ, Schiffer JT, Cohn LB, Deeks SG, Nussenzweig MC. PMID: 37443365; PMCID: PMC10345136.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Transcriptional and chromatin profiling of human blood innate lymphoid cell subsets sheds light on HIV-1 pathogenesis. EMBO J. 2023 08 15; 42(16):e114153.
Wang Y, Lifshitz L, Silverstein NJ, Mintzer E, Luk K, StLouis P, Brehm MA, Wolfe SA, Deeks SG, Luban J. PMID: 37382276; PMCID: PMC10425848.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Effect of Immune-Modulatory Interventions on Asymptomatic Cytomegalovirus Shedding During Suppressive Antiretroviral Therapy. J Infect Dis. 2023 06 28; 228(1):64-69.
Hastie E, Moser C, Sun X, Lennox J, Hsue PY, Bosch RJ, Deeks S, Meneses MV, Lederman MM, Hunt P, Henrich TJ, Marconi VC, Gianella S. PMID: 36881933; PMCID: PMC10490531.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Researching COVID to Enhance Recovery (RECOVER) adult study protocol: Rationale, objectives, and design. PLoS One. 2023; 18(6):e0286297.
Horwitz LI, Thaweethai T, Brosnahan SB, Cicek MS, Fitzgerald ML, Goldman JD, Hess R, Hodder SL, Jacoby VL, Jordan MR, Krishnan JA, Laiyemo AO, Metz TD, Nichols L, Patzer RE, Sekar A, Singer NG, Stiles LE, Taylor BS, Ahmed S, Algren HA, Anglin K, Aponte-Soto L, Ashktorab H, Bassett IV, Bedi B, Bhadelia N, Bime C, Bind MC, Black LJ, Blomkalns AL, Brim H, Castro M, Chan J, Charney AW, Chen BK, Chen LQ, Chen P, Chestek D, Chibnik LB, Chow DC, Chu HY, Clifton RG, Collins S, Costantine MM, Cribbs SK, Deeks SG, Dickinson JD, Donohue SE, Durstenfeld MS, Emery IF, Erlandson KM, Facelli JC, Farah-Abraham R, Finn AV, Fischer MS, Flaherman VJ, Fleurimont J, Fonseca V, Gallagher EJ, Gander JC, Gennaro ML, Gibson KS, Go M, Goodman SN, Granger JP, Greenway FL, Hafner JW, Han JE, Harkins MS, Hauser KSP, Heath JR, Hernandez CR, Ho O, Hoffman MK, Hoover SE, Horowitz CR, Hsu H, Hsue PY, Hughes BL, Jagannathan P, James JA, John J, Jolley S, Judd SE, Juskowich JJ, Kanjilal DG, Karlson EW, Katz SD, Kelly JD, Kelly SW, Kim AY, Kirwan JP, Knox KS, Kumar A, Lamendola-Essel MF, Lanca M, Lee-Lannotti JK, Lefebvre RC, Levy BD, Lin JY, Logarbo BP, Logue JK, Longo MT, Luciano CA, Lutrick K, Malakooti SK, Mallett G, Maranga G, Marathe JG, Marconi VC, Marshall GD, Martin CF, Martin JN, May HT, McComsey GA, McDonald D, Mendez-Figueroa H, Miele L, Mittleman MA, Mohandas S, Mouchati C, Mullington JM, Nadkarni GN, Nahin ER, Neuman RB, Newman LT, Nguyen A, Nikolich JZ, Ofotokun I, Ogbogu PU, Palatnik A, Palomares KTS, Parimon T, Parry S, Parthasarathy S, Patterson TF, Pearman A, Peluso MJ, Pemu P, Pettker CM, Plunkett BA, Pogreba-Brown K, Poppas A, Porterfield JZ, Quigley JG, Quinn DK, Raissy H, Rebello CJ, Reddy UM, Reece R, Reeder HT, Rischard FP, Rosas JM, Rosen CJ, Rouphael NG, Rouse DJ, Ruff AM, Saint Jean C, Sandoval GJ, Santana JL, Schlater SM, Sciurba FC, Selvaggi C, Seshadri S, Sesso HD, Shah DP, Shemesh E, Sherif ZA, Shinnick DJ, Simhan HN, Singh U, Sowles A, Subbian V, Sun J, Suthar MS, Teunis LJ, Thorp JM, Ticotsky A, Tita ATN, Tragus R, Tuttle KR, Urdaneta AE, Utz PJ, VanWagoner TM, Vasey A, Vernon SD, Vidal C, Walker T, Ward HD, Warren DE, Weeks RM, Weiner SJ, Weyer JC, Wheeler JL, Whiteheart SW, Wiley Z, Williams NJ, Wisnivesky JP, Wood JC, Yee LM, Young NM, Zisis SN, Foulkes AS. PMID: 37352211; PMCID: PMC10289397.
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PubMed Mentions:
9 Fields:
Translation:
HumansCellsCTClinical Trials
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Prevention, treatment and cure of HIV infection. Nat Rev Microbiol. 2023 10; 21(10):657-670.
Landovitz RJ, Scott H, Deeks SG. PMID: 37344551.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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Association of Culturable-Virus Detection and Household Transmission of SARS-CoV-2, California and Tennessee, 2020-2022. J Infect Dis. 2023 06 15; 227(12):1343-1347.
Deyoe JE, Kelly JD, Grijalva CG, Bonenfant G, Lu S, Anglin K, Garcia-Knight M, Pineda-Ramirez J, Hagen MB, Saydah S, Abedi GR, Goldberg SA, Tassetto M, Zhang A, Donohue KC, Davidson MC, Sanchez RD, Djomaleu M, Mathur S, Shak JR, Deeks SG, Peluso MJ, Chiu CY, Zhu Y, Halasa NB, Chappell JD, Mellis A, Reed C, Andino R, Martin JN, Zhou B, Talbot HK, Midgley CM, Rolfes MA. PMID: 36705269; PMCID: PMC10266938.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection. JAMA. 2023 06 13; 329(22):1934-1946.
Thaweethai T, Jolley SE, Karlson EW, Levitan EB, Levy B, McComsey GA, McCorkell L, Nadkarni GN, Parthasarathy S, Singh U, Walker TA, Selvaggi CA, Shinnick DJ, Schulte CCM, Atchley-Challenner R, Alba GA, Alicic R, Altman N, Anglin K, Argueta U, Ashktorab H, Baslet G, Bassett IV, Bateman L, Bedi B, Bhattacharyya S, Bind MA, Blomkalns AL, Bonilla H, Brim H, Bush PA, Castro M, Chan J, Charney AW, Chen P, Chibnik LB, Chu HY, Clifton RG, Costantine MM, Cribbs SK, Davila Nieves SI, Deeks SG, Duven A, Emery IF, Erdmann N, Erlandson KM, Ernst KC, Farah-Abraham R, Farner CE, Feuerriegel EM, Fleurimont J, Fonseca V, Franko N, Gainer V, Gander JC, Gardner EM, Geng LN, Gibson KS, Go M, Goldman JD, Grebe H, Greenway FL, Habli M, Hafner J, Han JE, Hanson KA, Heath J, Hernandez C, Hess R, Hodder SL, Hoffman MK, Hoover SE, Huang B, Hughes BL, Jagannathan P, John J, Jordan MR, Katz SD, Kaufman ES, Kelly JD, Kelly SW, Kemp MM, Kirwan JP, Klein JD, Knox KS, Krishnan JA, Kumar A, Laiyemo AO, Lambert AA, Lanca M, Lee-Iannotti JK, Logarbo BP, Longo MT, Luciano CA, Lutrick K, Maley JH, Mallett G, Marathe JG, Marconi V, Marshall GD, Martin CF, Matusov Y, Mehari A, Mendez-Figueroa H, Mermelstein R, Metz TD, Morse R, Mosier J, Mouchati C, Mullington J, Murphy SN, Neuman RB, Nikolich JZ, Ofotokun I, Ojemakinde E, Palatnik A, Palomares K, Parimon T, Parry S, Patterson JE, Patterson TF, Patzer RE, Peluso MJ, Pemu P, Pettker CM, Plunkett BA, Pogreba-Brown K, Poppas A, Quigley JG, Reddy U, Reece R, Reeder H, Reeves WB, Reiman EM, Rischard F, Rosand J, Rouse DJ, Ruff A, Saade G, Sandoval GJ, Santana JL, Schlater SM, Sciurba FC, Shepherd F, Sherif ZA, Simhan H, Singer NG, Skupski DW, Sowles A, Sparks JA, Sukhera FI, Taylor BS, Teunis L, Thomas RJ, Thorp JM, Thuluvath P, Ticotsky A, Tita AT, Tuttle KR, Urdaneta AE, Valdivieso D, VanWagoner TM, Vasey A, Verduzco-Gutierrez M, Wallace ZS, Ward HD, Warren DE, Weiner SJ, Welch S, Whiteheart SW, Wiley Z, Wisnivesky JP, Yee LM, Zisis S, Horwitz LI, Foulkes AS, RECOVER Consortium. PMID: 37278994; PMCID: PMC10214179.
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PubMed Mentions:
202 Fields:
Translation:
HumansCells
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Autoantigen profiling reveals a shared post-COVID signature in fully recovered and long COVID patients. JCI Insight. 2023 06 08; 8(11).
Bodansky A, Wang CY, Saxena A, Mitchell A, Kung AF, Takahashi S, Anglin K, Huang B, Hoh R, Lu S, Goldberg SA, Romero J, Tran B, Kirtikar R, Grebe H, So M, Greenhouse B, Durstenfeld MS, Hsue PY, Hellmuth J, Kelly JD, Martin JN, Anderson MS, Deeks SG, Henrich TJ, DeRisi JL, Peluso MJ. PMID: 37288661; PMCID: PMC10393220.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Association of SARS-CoV-2 Infection and Cardiopulmonary Long COVID with Exercise Capacity and Chronotropic Incompetence among People with HIV. medRxiv. 2023 May 02.
Durstenfeld MS, Peluso MJ, Spinelli MA, Li D, Hoh R, Gandhi M, Henrich TJ, Aras MA, Long CS, Deeks SG, Hsue PY. PMID: 37205522; PMCID: PMC10187359.
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PubMed Mentions:
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MultiSero: An Open-Source Multiplex-ELISA Platform for Measuring Antibody Responses to Infection. Pathogens. 2023 May 02; 12(5).
Byrum JR, Waltari E, Janson O, Guo SM, Folkesson J, Chhun BB, Vinden J, Ivanov IE, Forst ML, Li H, Larson AG, Blackmon L, Liu Z, Wu W, Ahyong V, Tato CM, McCutcheon KM, Hoh R, Kelly JD, Martin JN, Peluso MJ, Henrich TJ, Deeks SG, Prakash M, Greenhouse B, Mehta SB, Pak JE. PMID: 37242341; PMCID: PMC10221076.
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PubMed Mentions:
6
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SIV clearance from neonatal macaques following transient CCR5 depletion. bioRxiv. 2023 May 01.
Deere JD, Merriam D, Leggat KM, Chang WW, Méndez-Lagares G, Kieu H, Dutra J, Fontaine J, Lu W, Chin N, Chen C, Tran BC, Salinas J, Miller CN, Deeks SG, Lifson JD, Engelman K, Magnani D, Reimann K, Stevenson M, Hartigan-O'Connor DJ. PMID: 37205470; PMCID: PMC10187202.
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PubMed Mentions:
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A cell-free antigen processing system informs HIV-1 epitope selection and vaccine design. J Exp Med. 2023 07 03; 220(7).
Sengupta S, Zhang J, Reed MC, Yu J, Kim A, Boronina TN, Board NL, Wrabl JO, Shenderov K, Welsh RA, Yang W, Timmons AE, Hoh R, Cole RN, Deeks SG, Siliciano JD, Siliciano RF, Sadegh-Nasseri S. PMID: 37058141; PMCID: PMC10114365.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Correction: Towards access for all: 1st Working Group Report for the Global Gene Therapy Initiative (GGTI). Gene Ther. 2023 Apr; 30(3-4):405.
Adair JE, Androski L, Bayigga L, Bazira D, Brandon E, Dee L, Deeks S, Draz M, Dubé K, Dybul M, Gurkan U, Harlow E, Kityo C, Louella M, Malik P, Mathews V, McKemey A, Mugerwa H, Muyanja D, Olayiwola O, Orentas RJ, Popovski A, Sheehy J, Ssali F, Nsubuga MS, Tisdale JF, Verhoeyen E, Dropulic B. PMID: 34584245; PMCID: PMC10300648.
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PubMed Mentions: Fields:
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Viral and Host Mediators of Non-Suppressible HIV-1 Viremia. medRxiv. 2023 Mar 31.
Mohammadi A, Etemad B, Zhang X, Li Y, Bedwell GJ, Sharaf R, Kittilson A, Melberg M, Wong C, Fajnzylber J, Worrall DP, Rosenthal A, Jordan H, Jilg N, Kaseke C, Giguel F, Lian X, Deo R, Gillespie E, Chishti R, Abrha S, Adams T, Siagian A, Anderson PL, Deeks SG, Lederman MM, Yawetz S, Kuritzkes DR, Lichterfeld MD, Tsibris A, Carrington M, Brumme ZL, Castillo-Mancilla JR, Engelman AN, Gaiha GD, Li JZ. PMID: 37034605; PMCID: PMC10081408.
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PubMed Mentions:
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The Breadth of the Neutralizing Antibody Response to Original SARS-CoV-2 Infection is Linked to the Presence of Long COVID Symptoms. medRxiv. 2023 Mar 31.
Buck AM, Deitchman AN, Takahashi S, Lu S, Goldberg SA, Hoh R, Williams MC, Kerbleski M, Deveau TM, Munter SE, Lombardo J, Wrin T, Petropoulos CJ, Durstenfeld MS, Hsue PY, Kelly JD, Greenhouse B, Martin JN, Deeks SG, Peluso MJ, Henrich TJ. PMID: 37034660; PMCID: PMC10081395.
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PubMed Mentions:
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Soluble immune checkpoints as correlates for HIV persistence and T cell function in people with HIV on antiretroviral therapy. Front Immunol. 2023; 14:1123342.
Chiu CY, Schou MD, McMahon JH, Deeks SG, Fromentin R, Chomont N, Wykes MN, Rasmussen TA, Lewin SR. PMID: 37056754; PMCID: PMC10086427.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Reduced exercise capacity, chronotropic incompetence, and early systemic inflammation in cardiopulmonary phenotype Long COVID. medRxiv. 2023 Mar 21.
Durstenfeld MS, Peluso MJ, Kaveti P, Hill C, Li D, Sander E, Swaminathan S, Arechiga VM, Lu S, Goldberg SA, Hoh R, Chenna A, Yee BC, Winslow JW, Petropoulos CJ, Kelly JD, Glidden DV, Henrich TJ, Martin JN, Lee YJ, Aras MA, Long CS, Grandis DJ, Deeks SG, Hsue PY. PMID: 35677073; PMCID: PMC9176659.
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PubMed Mentions:
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Autoantigen profiling reveals a shared post-COVID signature in fully recovered and Long COVID patients. medRxiv. 2023 Feb 09.
Bodansky A, Wang CY, Saxena A, Mitchell A, Takahashi S, Anglin K, Huang B, Hoh R, Lu S, Goldberg SA, Romero J, Tran B, Kirtikar R, Grebe H, So M, Greenhouse B, Durstenfeld MS, Hsue PY, Hellmuth J, Kelly JD, Martin JN, Anderson MS, Deeks SG, Henrich TJ, DeRisi JL, Peluso MJ. PMID: 36798288; PMCID: PMC9934805.
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PubMed Mentions:
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Chronic viral coinfections differentially affect the likelihood of developing long COVID. J Clin Invest. 2023 02 01; 133(3).
Peluso MJ, Deveau TM, Munter SE, Ryder D, Buck A, Beck-Engeser G, Chan F, Lu S, Goldberg SA, Hoh R, Tai V, Torres L, Iyer NS, Deswal M, Ngo LH, Buitrago M, Rodriguez A, Chen JY, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Deitchman AN, Hellmuth J, Spinelli MA, Durstenfeld MS, Hsue PY, Kelly JD, Martin JN, Deeks SG, Hunt PW, Henrich TJ. PMID: 36454631; PMCID: PMC9888380.
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PubMed Mentions:
63 Fields:
Translation:
HumansCells
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Rebound HIV-1 in cerebrospinal fluid after antiviral therapy interruption is mainly clonally amplified R5 T cell-tropic virus. Nat Microbiol. 2023 02; 8(2):260-271.
Kincer LP, Joseph SB, Gilleece MM, Hauser BM, Sizemore S, Zhou S, Di Germanio C, Zetterberg H, Fuchs D, Deeks SG, Spudich S, Gisslen M, Price RW, Swanstrom R. PMID: 36717718; PMCID: PMC10201410.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Unequal distribution of genetically-intact HIV-1 proviruses in cells expressing the immune checkpoint markers PD-1 and/or CTLA-4. Front Immunol. 2023; 14:1064346.
Fisher K, Schlub TE, Boyer Z, Rasmussen TA, Rhodes A, Hoh R, Hecht FM, Deeks SG, Lewin SR, Palmer S. PMID: 36776833; PMCID: PMC9909745.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Differences in expression of tumor suppressor, innate immune, inflammasome, and potassium/gap junction channel host genes significantly predict viral reservoir size during treated HIV infection. bioRxiv. 2023 Jan 12.
Dwivedi AK, Siegel DA, Thanh C, Hoh R, Hobbs KS, Pan T, Gibson EA, Martin J, Hecht F, Pilcher C, Milush J, Busch MP, Stone M, Huang ML, Levy CN, Roychoudhury P, Hladik F, Jerome KR, Henrich TJ, Deeks SG, Lee SA. PMID: 36712077; PMCID: PMC9882059.
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PubMed Mentions:
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Low Prevalence of Interferon α Autoantibodies in People Experiencing Symptoms of Post-Coronavirus Disease 2019 (COVID-19) Conditions, or Long COVID. J Infect Dis. 2023 01 11; 227(2):246-250.
Peluso MJ, Mitchell A, Wang CY, Takahashi S, Hoh R, Tai V, Durstenfeld MS, Hsue PY, Kelly JD, Martin JN, Wilson MR, Greenhouse B, Deeks SG, DeRisi JL, Henrich TJ. PMID: 36089700; PMCID: PMC9494362.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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HIV silencing and cell survival signatures in infected T cell reservoirs. Nature. 2023 02; 614(7947):318-325.
Clark IC, Mudvari P, Thaploo S, Smith S, Abu-Laban M, Hamouda M, Theberge M, Shah S, Ko SH, Pérez L, Bunis DG, Lee JS, Kilam D, Zakaria S, Choi S, Darko S, Henry AR, Wheeler MA, Hoh R, Butrus S, Deeks SG, Quintana FJ, Douek DC, Abate AR, Boritz EA. PMID: 36599978; PMCID: PMC9908556.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Progressive transformation of the HIV-1 reservoir cell profile over two decades of antiviral therapy. Cell Host Microbe. 2023 01 11; 31(1):83-96.e5.
Lian X, Seiger KW, Parsons EM, Gao C, Sun W, Gladkov GT, Roseto IC, Einkauf KB, Osborn MR, Chevalier JM, Jiang C, Blackmer J, Carrington M, Rosenberg ES, Lederman MM, McMahon DK, Bosch RJ, Jacobson JM, Gandhi RT, Peluso MJ, Chun TW, Deeks SG, Yu XG, Lichterfeld M. PMID: 36596305; PMCID: PMC9839361.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Transcriptomic Signatures of Human Immunodeficiency Virus Post-Treatment Control. J Virol. 2023 01 31; 97(1):e0125422.
Wedrychowski A, Martin HA, Li Y, Telwatte S, Kadiyala GN, Melberg M, Etemad B, Connick E, Jacobson JM, Margolis DM, Skiest D, Volberding P, Hecht F, Deeks S, Wong JK, Li JZ, Yukl SA. PMID: 36541802; PMCID: PMC9888280.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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New Assay Reveals Vast Excess of Defective over Intact HIV-1 Transcripts in Antiretroviral Therapy-Suppressed Individuals. J Virol. 2022 12 21; 96(24):e0160522.
Martin HA, Kadiyala GN, Telwatte S, Wedrychowski A, Chen TH, Moron-Lopez S, Arneson D, Hoh R, Deeks S, Wong J, Yukl SA. PMID: 36448806; PMCID: PMC9769383.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Host variation in type I interferon signaling genes (MX1), C-C chemokine receptor type 5 gene, and major histocompatibility complex class I alleles in treated HIV+ noncontrollers predict viral reservoir size. AIDS. 2023 03 01; 37(3):477-488.
Siegel DA, Thanh C, Wan E, Hoh R, Hobbs K, Pan T, Gibson EA, Kroetz DL, Martin J, Hecht F, Pilcher C, Martin M, Carrington M, Pillai S, Busch MP, Stone M, Levy CN, Huang ML, Roychoudhury P, Hladik F, Jerome KR, Kiem HP, Henrich TJ, Deeks SG, Lee SA. PMID: 36695358; PMCID: PMC9894159.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Persistence of envelopes in different CD4+ T-cell subsets in antiretroviral therapy-suppressed people with HIV. AIDS. 2023 02 01; 37(2):247-257.
Gartner MJ, Tumpach C, Dantanarayana A, Stern J, Zerbato JM, Chang JJ, Angelovich TA, Anderson JL, Symons J, Deeks SG, Flynn JK, Lewin SR, Churchill MJ, Gorry PR, Roche M. PMID: 36541637; PMCID: PMC9794144.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Willingness of Racially Diverse Young Adults Living with HIV to Participate in HIV Cure Research: A Cross-Sectional Survey in the United States. AIDS Res Hum Retroviruses. 2023 08; 39(8):381-399.
Dubé K, Campbell CK, Eskaf S, Sauceda JA, Ndukwe S, Henley L, Persaud D, Deeks SG, Auerbach JD, Saberi P. PMID: 36226414; PMCID: PMC10387162.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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In vivo killing of primary HIV-infected cells by peripheral-injected early memory-enriched anti-HIV duoCAR T cells. JCI Insight. 2022 11 08; 7(21).
Anthony-Gonda K, Ray A, Su H, Wang Y, Xiong Y, Lee D, Block A, Chilunda V, Weiselberg J, Zemelko L, Wang YY, Kleinsorge-Block S, Reese JS, de Lima M, Ochsenbauer C, Kappes JC, Dimitrov DS, Orentas R, Deeks SG, Rutishauser RL, Berman JW, Goldstein H, Dropulic B. PMID: 36345941; PMCID: PMC9675454.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Evaluation of Severe Acute Respiratory Syndrome Coronavirus 2 Nucleocapsid Antigen in the Blood as a Diagnostic Test for Infection and Infectious Viral Shedding. Open Forum Infect Dis. 2022 Nov; 9(11):ofac563.
Mathur S, Davidson MC, Anglin K, Lu S, Goldberg SA, Garcia-Knight M, Tassetto M, Zhang A, Romero M, Pineda-Ramirez J, Diaz-Sanchez R, Rugart P, Chen JY, Donohue K, Shak JR, Chenna A, Winslow JW, Petropoulos CJ, Yee BC, Lambert J, Glidden DV, Rutherford GW, Deeks SG, Peluso MJ, Andino R, Martin JN, Kelly JD. PMID: 36381627; PMCID: PMC9620332.
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PubMed Mentions:
5
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Impact of Tamoxifen on Vorinostat-Induced Human Immunodeficiency Virus Expression in Women on Antiretroviral Therapy: AIDS Clinical Trials Group A5366, The MOXIE Trial. Clin Infect Dis. 2022 10 12; 75(8):1389-1396.
Scully EP, Aga E, Tsibris A, Archin N, Starr K, Ma Q, Morse GD, Squires KE, Howell BJ, Wu G, Hosey L, Sieg SF, Ehui L, Giguel F, Coxen K, Dobrowolski C, Gandhi M, Deeks S, Chomont N, Connick E, Godfrey C, Karn J, Kuritzkes DR, Bosch RJ, Gandhi RT. PMID: 35176755; PMCID: PMC9555843.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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A common allele of HLA mediates asymptomatic SARS-CoV-2 infection. medRxiv. 2022 Oct 12.
Augusto DG, Yusufali T, Sabatino JJ, Peyser ND, Murdolo LD, Butcher X, Murray V, Pae V, Sarvadhavabhatla S, Beltran F, Gill G, Lynch K, Yun C, Maguire C, Peluso MJ, Hoh R, Henrich TJ, Deeks SG, Davidson M, Lu S, Goldberg SA, Kelly JD, Martin JN, Viera-Green CA, Spellman SR, Langton DJ, Lee S, Marcus GM, Olgin JE, Pletcher MJ, Gras S, Maiers M, Hollenbach JA. PMID: 34031661; PMCID: PMC8142661.
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PubMed Mentions:
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Memory CD4+ T cells that co-express PD1 and CTLA4 have reduced response to activating stimuli facilitating HIV latency. Cell Rep Med. 2022 10 18; 3(10):100766.
Rasmussen TA, Zerbato JM, Rhodes A, Tumpach C, Dantanarayana A, McMahon JH, Lau JSY, Chang JJ, Gubser C, Brown W, Hoh R, Krone M, Pascoe R, Chiu CY, Bramhall M, Lee HJ, Haque A, Fromentin R, Chomont N, Milush J, Van der Sluis RM, Palmer S, Deeks SG, Cameron PU, Evans V, Lewin SR. PMID: 36198308; PMCID: PMC9589005.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
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View in:
PubMed Mentions:
53 Fields:
Translation:
HumansCells
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Magnitude and Determinants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Household Transmission: A Longitudinal Cohort Study. Clin Infect Dis. 2022 10 03; 75(Suppl 2):S193-S204.
Kelly JD, Lu S, Anglin K, Garcia-Knight M, Pineda-Ramirez J, Goldberg SA, Tassetto M, Zhang A, Donohue K, Davidson MC, Romero M, Diaz Sanchez R, Djomaleu M, Mathur S, Chen JY, Forman CA, Servellita V, Montejano RD, Shak JR, Rutherford GW, Deeks SG, Abedi GR, Rolfes MA, Saydah S, Briggs-Hagen M, Peluso MJ, Chiu C, Midgley CM, Andino R, Martin JN. PMID: 35788827; PMCID: PMC9278251.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Markers of fungal translocation are elevated during post-acute sequelae of SARS-CoV-2 and induce NF-κB signaling. JCI Insight. 2022 Sep 22; 7(18).
Giron LB, Peluso MJ, Ding J, Kenny G, Zilberstein NF, Koshy J, Hong KY, Rasmussen H, Miller GE, Bishehsari F, Balk RA, Moy JN, Hoh R, Lu S, Goldman AR, Tang HY, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Kelly JD, Wasse H, Martin JN, Liu Q, Keshavarzian A, Landay A, Deeks SG, Henrich TJ, Abdel-Mohsen M. PMID: 36134654; PMCID: PMC9675436.
View in:
PubMed Mentions:
8 Fields:
-
Infectious viral shedding of SARS-CoV-2 Delta following vaccination: A longitudinal cohort study. PLoS Pathog. 2022 09; 18(9):e1010802.
Garcia-Knight M, Anglin K, Tassetto M, Lu S, Zhang A, Goldberg SA, Catching A, Davidson MC, Shak JR, Romero M, Pineda-Ramirez J, Diaz-Sanchez R, Rugart P, Donohue K, Massachi J, Sans HM, Djomaleu M, Mathur S, Servellita V, McIlwain D, Gaudiliere B, Chen J, Martinez EO, Tavs JM, Bronstone G, Weiss J, Watson JT, Briggs-Hagen M, Abedi GR, Rutherford GW, Deeks SG, Chiu C, Saydah S, Peluso MJ, Midgley CM, Martin JN, Andino R, Kelly JD. PMID: 36095030; PMCID: PMC9499220.
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PubMed Mentions:
24 Fields:
Translation:
HumansCellsPHPublic Health
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CCL2: a Chemokine Potentially Promoting Early Seeding of the Latent HIV Reservoir. mBio. 2022 10 26; 13(5):e0189122.
Packard TA, Schwarzer R, Herzig E, Rao D, Luo X, Egedal JH, Hsiao F, Widera M, Hultquist JF, Grimmett ZW, Messer RJ, Krogan NJ, Deeks SG, Roan NR, Dittmer U, Hasenkrug KJ, Greene WC. PMID: 36073812; PMCID: PMC9600577.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Differences in Post-mRNA Vaccination Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Immunoglobulin G (IgG) Concentrations and Surrogate Virus Neutralization Test Response by Human Immunodeficiency Virus (HIV) Status and Type of Vaccine: A Matched Case-Control Observational Study. Clin Infect Dis. 2022 08 24; 75(1):e916-e919.
Spinelli MA, Peluso MJ, Lynch KL, Yun C, Glidden DV, Henrich TJ, Deeks SG, Gandhi M. PMID: 34864962; PMCID: PMC8689738.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCellsPHPublic Health
-
Markers of fungal translocation are elevated during post-acute sequelae of SARS-CoV-2 and induce NF-κB signaling. JCI Insight. 2022 08 08; 7(15).
Giron LB, Peluso MJ, Ding J, Kenny G, Zilberstein NF, Koshy J, Hong KY, Rasmussen H, Miller GE, Bishehsari F, Balk RA, Moy JN, Hoh R, Lu S, Goldman AR, Tang HY, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Kelly JD, Wasse H, Martin JN, Liu Q, Keshavarzian A, Landay A, Deeks SG, Henrich TJ, Abdel-Mohsen M. PMID: 35727635; PMCID: PMC9462470.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Methotrexate Inhibits T Cell Proliferation but Not Inflammatory Cytokine Expression to Modulate Immunity in People Living With HIV. Front Immunol. 2022; 13:924718.
Freeman ML, Clagett BM, Moisi D, Yeh E, Morris CD, Ryu A, Rodriguez B, Stein JH, Deeks SG, Currier JS, Hsue PY, Anthony DD, Calabrese LH, Ribaudo HJ, Lederman MM. PMID: 35967371; PMCID: PMC9374564.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
Impact of Pre-Existing Chronic Viral Infection and Reactivation on the Development of Long COVID. medRxiv. 2022 Jul 22.
Peluso MJ, Deveau TM, Munter SE, Ryder D, Buck A, Beck-Engeser G, Chan F, Lu S, Goldberg SA, Hoh R, Tai V, Torres L, Iyer NS, Deswal M, Ngo LH, Buitrago M, Rodriguez A, Chen JY, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Deitchman AN, Hellmuth J, Spinelli MA, Durstenfeld MS, Hsue PY, Kelly JD, Martin JN, Deeks SG, Hunt PW, Henrich TJ. PMID: 35898346; PMCID: PMC9327632.
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PubMed Mentions:
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Comparative immunogenicity of an mRNA/LNP and a DNA vaccine targeting HIV gag conserved elements in macaques. Front Immunol. 2022; 13:945706.
Valentin A, Bergamaschi C, Rosati M, Angel M, Burns R, Agarwal M, Gergen J, Petsch B, Oostvogels L, Loeliger E, Chew KW, Deeks SG, Mullins JI, Pavlakis GN, Felber BK. PMID: 35935984; PMCID: PMC9355630.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
-
Postacute sequelae and adaptive immune responses in people with HIV recovering from SARS-COV-2 infection. AIDS. 2022 10 01; 36(12):F7-F16.
Peluso MJ, Spinelli MA, Deveau TM, Forman CA, Munter SE, Mathur S, Tang AF, Lu S, Goldberg SA, Arreguin MI, Hoh R, Tai V, Chen JY, Martinez EO, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Sette A, Weiskopf D, Kumar N, Lynch KL, Hunt PW, Durstenfeld MS, Hsue PY, Kelly JD, Martin JN, Glidden DV, Gandhi M, Deeks SG, Rutishauser RL, Henrich TJ. PMID: 35866847; PMCID: PMC9444925.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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LOXL-2 and TNC-C are markers of liver fibrogenesis in HCV/HIV-, HIV- and HCV-infected patients. Biomark Med. 2022 08; 16(11):839-846.
Altinbas A, Holmes JA, Salloum S, Lidofsky A, Alatrakchi N, Somsouk M, Hunt P, Deeks S, Chew KW, Lauer G, Kruger A, Lin W, Chung RT. PMID: 35786977; PMCID: PMC9437769.
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PubMed Mentions:
1 Fields:
Translation:
Humans
-
View in:
PubMed Mentions:
24
-
View in:
PubMed Mentions:
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Plasma Markers of Neurologic Injury and Inflammation in People With Self-Reported Neurologic Postacute Sequelae of SARS-CoV-2 Infection. Neurol Neuroimmunol Neuroinflamm. 2022 09; 9(5).
Peluso MJ, Sans HM, Forman CA, Nylander AN, Ho HE, Lu S, Goldberg SA, Hoh R, Tai V, Munter SE, Chenna A, Yee BC, Winslow JW, Petropoulos CJ, Martin JN, Kelly JD, Durstenfeld MS, Hsue PY, Hunt PW, Greene M, Chow FC, Hellmuth J, Henrich TJ, Glidden DV, Deeks SG. PMID: 35701186; PMCID: PMC9210548.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansCells
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Lack of Antinuclear Antibodies in Convalescent Coronavirus Disease 2019 Patients With Persistent Symptoms. Clin Infect Dis. 2022 06 10; 74(11):2083-2084.
Peluso MJ, Thomas IJ, Munter SE, Deeks SG, Henrich TJ. PMID: 34617982; PMCID: PMC9187313.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Predictive value of CD8+ T cell and CD4/CD8 ratio at two years of successful ART in the risk of AIDS and non-AIDS events. EBioMedicine. 2022 Jun; 80:104072.
Serrano-Villar S, Wu K, Hunt PW, Lok JJ, Ron R, Sainz T, Moreno S, Deeks SG, Bosch RJ. PMID: 35644125; PMCID: PMC9156990.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Role of antibodies, inflammatory markers, and echocardiographic findings in postacute cardiopulmonary symptoms after SARS-CoV-2 infection. JCI Insight. 2022 05 23; 7(10).
Durstenfeld MS, Peluso MJ, Kelly JD, Win S, Swaminathan S, Li D, Arechiga VM, Zepeda V, Sun K, Shao S, Hill C, Arreguin MI, Lu S, Hoh R, Tai V, Chenna A, Yee BC, Winslow JW, Petropoulos CJ, Kornak J, Henrich TJ, Martin JN, Deeks SG, Hsue PY. PMID: 35389890; PMCID: PMC9220849.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Cell-Associated Human Immunodeficiency Virus (HIV) Ribonucleic Acid Has a Circadian Cycle in Males With HIV on Antiretroviral Therapy. J Infect Dis. 2022 05 16; 225(10):1721-1730.
Stern J, Solomon A, Dantanarayana A, Pascoe R, Reynaldi A, Davenport MP, Milush J, Deeks SG, Hartogensis W, Hecht FM, Cockerham L, Roche M, Lewin SR. PMID: 34655216; PMCID: PMC9633724.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Gut-derived bacterial toxins impair memory CD4+ T cell mitochondrial function in HIV-1 infection. J Clin Invest. 2022 05 02; 132(9).
Ferrari B, Da Silva AC, Liu KH, Saidakova EV, Korolevskaya LB, Shmagel KV, Shive C, Pacheco Sanchez G, Retuerto M, Sharma AA, Ghneim K, Noel-Romas L, Rodriguez B, Ghannoum MA, Hunt PP, Deeks SG, Burgener AD, Jones DP, Dobre MA, Marconi VC, Sekaly RP, Younes SA. PMID: 35316209; PMCID: PMC9057623.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Variation in blood microbial lipopolysaccharide (LPS) contributes to immune reconstitution in response to suppressive antiretroviral therapy in HIV. EBioMedicine. 2022 06; 80:104037.
Luo Z, Health SL, Li M, Yang H, Wu Y, Collins M, Deeks SG, Martin JN, Scott A, Jiang W. PMID: 35500539; PMCID: PMC9065923.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Participant Perspectives and Experiences Following an Intensively Monitored Antiretroviral Pause in the United States: Results from the AIDS Clinical Trials Group A5345 Biomarker Study. AIDS Res Hum Retroviruses. 2022 06; 38(6):510-517.
Dubé K, Eskaf S, Barr L, Palm D, Hogg E, Simoni JM, Sugarman J, Brown B, Sauceda JA, Henley L, Deeks S, Fox L, Gandhi RT, Smith D, Li JZ. PMID: 35323030; PMCID: PMC9225827.
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PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
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Ethical and practical considerations for cell and gene therapy toward an HIV cure: findings from a qualitative in-depth interview study in the United States. BMC Med Ethics. 2022 04 09; 23(1):39.
Dubé K, Kanazawa J, Patel H, Louella M, Sylla L, Sheehy J, Dee L, Taylor J, Adair J, Anthony-Gonda K, Dropulic B, Sauceda JA, Peluso MJ, Deeks SG, Simoni J. PMID: 35397551; PMCID: PMC8994300.
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PubMed Mentions:
1 Fields:
Translation:
Humans
-
The RIO trial: rationale, design, and the role of community involvement in a randomised placebo-controlled trial of antiretroviral therapy plus dual long-acting HIV-specific broadly neutralising antibodies (bNAbs) in participants diagnosed with recent HIV infection-study protocol for a two-stage randomised phase II trial. Trials. 2022 Apr 05; 23(1):263.
Lee MJ, Collins S, Babalis D, Johnson N, Falaschetti E, Prevost AT, Ashraf A, Jacob M, Cole T, Hurley L, Pace M, Ogbe A, Khan M, Zacharopoulou P, Brown H, Sutherland E, Box H, Fox J, Deeks S, Horowitz J, Nussenzweig MC, Caskey M, Frater J, Fidler S. PMID: 35382844; PMCID: PMC8981886.
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PubMed Mentions:
2 Fields:
Translation:
HumansCellsCTClinical Trials
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Cellular Activation, Differentiation, and Proliferation Influence the Dynamics of Genetically Intact Proviruses Over Time. J Infect Dis. 2022 04 01; 225(7):1168-1178.
Horsburgh BA, Hiener B, Fisher K, Lee E, Morgan H, Eden JS, von Stockenstrom S, Odevall L, Milush JM, Hoh R, Fromentin R, Chomont N, Hecht FM, Schlub TE, Deeks SG, Palmer S. PMID: 34037766; PMCID: PMC8974828.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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The HIV-1 proviral landscape reveals that Nef contributes to HIV-1 persistence in effector memory CD4+ T cells. J Clin Invest. 2022 04 01; 132(7).
Duette G, Hiener B, Morgan H, Mazur FG, Mathivanan V, Horsburgh BA, Fisher K, Tong O, Lee E, Ahn H, Shaik A, Fromentin R, Hoh R, Bacchus-Souffan C, Nasr N, Cunningham AL, Hunt PW, Chomont N, Turville SG, Deeks SG, Kelleher AD, Schlub TE, Palmer S. PMID: 35133986; PMCID: PMC8970682.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansCells
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SARS-CoV-2 and Mitochondrial Proteins in Neural-Derived Exosomes of COVID-19. Ann Neurol. 2022 06; 91(6):772-781.
Peluso MJ, Deeks SG, Mustapic M, Kapogiannis D, Henrich TJ, Lu S, Goldberg SA, Hoh R, Chen JY, Martinez EO, Kelly JD, Martin JN, Goetzl EJ. PMID: 35285072; PMCID: PMC9082480.
View in:
PubMed Mentions:
53 Fields:
Translation:
HumansCells
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Plasma-Derived HIV-1 Virions Contain Considerable Levels of Defective Genomes. J Virol. 2022 03 23; 96(6):e0201121.
Fisher K, Wang XQ, Lee A, Morcilla V, de Vries A, Lee E, Eden JS, Deeks SG, Kelleher AD, Palmer S. PMID: 35201897; PMCID: PMC8941922.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCells
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First-in-human immunoPET imaging of HIV-1 infection using 89Zr-labeled VRC01 broadly neutralizing antibody. Nat Commun. 2022 03 09; 13(1):1219.
Beckford-Vera DR, Flavell RR, Seo Y, Martinez-Ortiz E, Aslam M, Thanh C, Fehrman E, Pardons M, Kumar S, Deitchman AN, Ravanfar V, Schulte B, Wu IK, Pan T, Reeves JD, Nixon CC, Iyer NS, Torres L, Munter SE, Hyunh T, Petropoulos CJ, Hoh R, Franc BL, Gama L, Koup RA, Mascola JR, Chomont N, Deeks SG, VanBrocklin HF, Henrich TJ. PMID: 35264559; PMCID: PMC8907355.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCellsCTClinical Trials
-
Time to Viral Rebound After Interruption of Modern Antiretroviral Therapies. Clin Infect Dis. 2022 03 09; 74(5):865-870.
Li JZ, Aga E, Bosch RJ, Pilkinton M, Kroon E, MacLaren L, Keefer M, Fox L, Barr L, Acosta E, Ananworanich J, Coombs R, Mellors JW, Landay AL, Macatangay B, Deeks S, Gandhi RT, Smith DM. PMID: 34117753; PMCID: PMC8906742.
View in:
PubMed Mentions:
29 Fields:
Translation:
Humans
-
IFN-α blockade during ART-treated SIV infection lowers tissue vDNA, rescues immune function, and improves overall health. JCI Insight. 2022 03 08; 7(5).
Swainson LA, Sharma AA, Ghneim K, Ribeiro SP, Wilkinson P, Dunham RM, Albright RG, Wong S, Estes JD, Piatak M, Deeks SG, Hunt PW, Sekaly RP, McCune JM. PMID: 35104248; PMCID: PMC8983135.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Early clues regarding the pathogenesis of long-COVID. Trends Immunol. 2022 04; 43(4):268-270.
Peluso MJ, Deeks SG. PMID: 35272932; PMCID: PMC8901423.
View in:
PubMed Mentions:
60 Fields:
Translation:
HumansCells
-
Findings From Mayo Clinic's Post-COVID Clinic: PASC Phenotypes Vary by Sex and Degree of IL-6 Elevation. Mayo Clin Proc. 2022 03; 97(3):430-432.
Durstenfeld MS, Hsue PY, Peluso MJ, Deeks SG. PMID: 35246280; PMCID: PMC8886352.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
SARS-CoV-2 Booster Vaccination for Participants in "HIV Cure"-Related Clinical Trials. J Acquir Immune Defic Syndr. 2022 03 01; 89(3):e30.
Peluso MJ, Williams MC, Campbell DM, Dee L, Taylor J, Ngo LH, Hoh R, Dubé K, Sauceda JA, Deeks SG. PMID: 35147584; PMCID: PMC8851852.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCellsPHPublic Health
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Fighting the SARS-CoV-2 pandemic requires a global approach to understanding the heterogeneity of vaccine responses. Nat Immunol. 2022 03; 23(3):360-370.
Tomalka JA, Suthar MS, Deeks SG, Sekaly RP. PMID: 35210622.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCellsPHPublic Health
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Mitigation strategies to safely conduct HIV treatment research in the context of COVID-19. J Int AIDS Soc. 2022 02; 25(2):e25882.
Henderson M, Fidler S, Mothe B, Grinsztejn B, Haire B, Collins S, Lau JSY, Luba M, Sanne I, Tatoud R, Deeks S, Lewin SR. PMID: 35138683; PMCID: PMC8826545.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCellsPHPublic Health
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Deep Phenotypic Analysis of Blood and Lymphoid T and NK Cells From HIV+ Controllers and ART-Suppressed Individuals. Front Immunol. 2022; 13:803417.
George AF, Luo X, Neidleman J, Hoh R, Vohra P, Thomas R, Shin MG, Lee MJ, Blish CA, Deeks SG, Greene WC, Lee SA, Roan NR. PMID: 35154118; PMCID: PMC8829545.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy. Sci Transl Med. 2022 01 26; 14(629):eabl3836.
Uldrick TS, Adams SV, Fromentin R, Roche M, Fling SP, Gonçalves PH, Lurain K, Ramaswami R, Wang CJ, Gorelick RJ, Welker JL, O'Donoghue L, Choudhary H, Lifson JD, Rasmussen TA, Rhodes A, Tumpach C, Yarchoan R, Maldarelli F, Cheever MA, Sékaly R, Chomont N, Deeks SG, Lewin SR. PMID: 35080914; PMCID: PMC9014398.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansCells
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Risk factors and abnormal cerebrospinal fluid associate with cognitive symptoms after mild COVID-19. Ann Clin Transl Neurol. 2022 02; 9(2):221-226.
Apple AC, Oddi A, Peluso MJ, Asken BM, Henrich TJ, Kelly JD, Pleasure SJ, Deeks SG, Allen IE, Martin JN, Ndhlovu LC, Miller BL, Stephens ML, Hellmuth J. PMID: 35043593; PMCID: PMC8862406.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansCells
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Randomized Trial of Ruxolitinib in Antiretroviral-Treated Adults With Human Immunodeficiency Virus. Clin Infect Dis. 2022 01 07; 74(1):95-104.
Marconi VC, Moser C, Gavegnano C, Deeks SG, Lederman MM, Overton ET, Tsibris A, Hunt PW, Kantor A, Sekaly RP, Tressler R, Flexner C, Hurwitz SJ, Moisi D, Clagett B, Hardin WR, Del Rio C, Schinazi RF, Lennox JJ. PMID: 33693561; PMCID: PMC8752257.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansCells
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Persistence, Magnitude, and Patterns of Postacute Symptoms and Quality of Life Following Onset of SARS-CoV-2 Infection: Cohort Description and Approaches for Measurement. Open Forum Infect Dis. 2022 Feb; 9(2):ofab640.
Peluso MJ, Kelly JD, Lu S, Goldberg SA, Davidson MC, Mathur S, Durstenfeld MS, Spinelli MA, Hoh R, Tai V, Fehrman EA, Torres L, Hernandez Y, Williams MC, Arreguin MI, Ngo LH, Deswal M, Munter SE, Martinez EO, Anglin KA, Romero MD, Tavs J, Rugart PR, Chen JY, Sans HM, Murray VW, Ellis PK, Donohue KC, Massachi JA, Weiss JO, Mehdi I, Pineda-Ramirez J, Tang AF, Wenger MA, Assenzio MT, Yuan Y, Krone MR, Rutishauser RL, Rodriguez-Barraquer I, Greenhouse B, Sauceda JA, Gandhi M, Scheffler AW, Hsue PY, Henrich TJ, Deeks SG, Martin JN. PMID: 35106317; PMCID: PMC8755302.
View in:
PubMed Mentions:
49
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Characterizing the COVID-19 Illness Experience to Inform the Study of Post-acute Sequelae and Recovery. Int J Behav Med. 2022 Oct; 29(5):610-623.
Santiago-Rodriguez EI, Maiorana A, Peluso MJ, Hoh R, Tai V, Fehrman EA, Hernandez Y, Torres L, Spinelli MA, Gandhi M, Kelly JD, Martin JN, Henrich TJ, Deeks SG, Sauceda JA. PMID: 34918211; PMCID: PMC8675303.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Signatures of immune selection in intact and defective proviruses distinguish HIV-1 elite controllers. Sci Transl Med. 2021 12 15; 13(624):eabl4097.
Lian X, Gao C, Sun X, Jiang C, Einkauf KB, Seiger KW, Chevalier JM, Yuki Y, Martin M, Hoh R, Peluso MJ, Carrington M, Ruiz-Mateos E, Deeks SG, Rosenberg ES, Walker BD, Lichterfeld M, Yu XG. PMID: 34910552; PMCID: PMC9202005.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansCells
-
Research priorities for an HIV cure: International AIDS Society Global Scientific Strategy 2021. Nat Med. 2021 12; 27(12):2085-2098.
Deeks SG, Archin N, Cannon P, Collins S, Jones RB, de Jong MAWP, Lambotte O, Lamplough R, Ndung'u T, Sugarman J, Tiemessen CT, Vandekerckhove L, Lewin SR, International AIDS Society (IAS) Global Scientific Strategy working group. PMID: 34848888.
View in:
PubMed Mentions:
110 Fields:
Translation:
Humans
-
Markers of Immune Activation and Inflammation in Individuals With Postacute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 Infection. J Infect Dis. 2021 12 01; 224(11):1839-1848.
Peluso MJ, Lu S, Tang AF, Durstenfeld MS, Ho HE, Goldberg SA, Forman CA, Munter SE, Hoh R, Tai V, Chenna A, Yee BC, Winslow JW, Petropoulos CJ, Greenhouse B, Hunt PW, Hsue PY, Martin JN, Daniel Kelly J, Glidden DV, Deeks SG, Henrich TJ. PMID: 34677601; PMCID: PMC8643408.
View in:
PubMed Mentions:
116 Fields:
Translation:
Humans
-
Identification and Characterization of Antigen-Specific CD8+ T Cells Using Surface-Trapped TNF-α and Single-Cell Sequencing. J Immunol. 2021 12 15; 207(12):2913-2921.
Abdulhaqq S, Ventura AB, Reed JS, Bashirova AA, Bateman KB, McDonald E, Wu HL, Greene JM, Schell JB, Morrow D, Wisskirchen K, Martin JN, Deeks SG, Carrington M, Protzer U, Früh K, Hansen SG, Picker LJ, Sacha JB, Bimber BN. PMID: 34810222; PMCID: PMC9124229.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
Gag p24 Is a Marker of Human Immunodeficiency Virus Expression in Tissues and Correlates With Immune Response. J Infect Dis. 2021 11 16; 224(9):1593-1598.
Wu G, Zuck P, Goh SL, Milush JM, Vohra P, Wong JK, Somsouk M, Yukl SA, Shacklett BL, Chomont N, Haase AT, Hatano H, Schacker TW, Deeks SG, Hazuda DJ, Hunt PW, Howell BJ. PMID: 33693750; PMCID: PMC8599810.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
-
A High Percentage of People With Human Immunodeficiency Virus (HIV) on Antiretroviral Therapy Experience Detectable Low-Level Plasma HIV-1 RNA Following Coronavirus Disease 2019 (COVID-19). Clin Infect Dis. 2021 11 02; 73(9):e2845-e2846.
Peluso MJ, Bakkour S, Busch MP, Deeks SG, Henrich TJ. PMID: 33211091; PMCID: PMC7717237.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Effect of HIV-1 Infection on Angiopoietin 1 and 2 Levels and Measures of Microvascular and Macrovascular Endothelial Dysfunction. J Am Heart Assoc. 2021 11 16; 10(22):e021397.
Thakkar AB, Ma Y, Dela Cruz M, Wu Y, Arechiga V, Swaminathan S, Ganz P, Wu AHB, Scherzer R, Deeks S, Hsue PY. PMID: 34726064; PMCID: PMC8751943.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Frequency of post treatment control varies by antiretroviral therapy restart and viral load criteria. AIDS. 2021 11 01; 35(13):2225-2227.
Fajnzylber J, Sharaf R, Hutchinson JN, Aga E, Bosch RJ, Hartogensis W, Jacobson JM, Connick E, Volberding P, Skiest DJ, Margolis D, Sneller MC, Little SJ, Gulick RM, Mellors JW, Gandhi RT, Schooley RT, Henry K, Tebas P, Deeks S, Chun TW, Collier AC, Hecht FM, Li JZ, CHAMP study team. PMID: 34127579; PMCID: PMC8490281.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Considerations for designing and implementing combination HIV cure trials: findings from a qualitative in-depth interview study in the United States. AIDS Res Ther. 2021 10 18; 18(1):75.
Dubé K, Kanazawa J, Dee L, Taylor J, Sauceda JA, Gianella S, Smith D, Deeks SG, Peluso MJ. PMID: 34663375; PMCID: PMC8522863.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
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Assessing the Suitability of Next-Generation Viral Outgrowth Assays to Measure Human Immunodeficiency Virus 1 Latent Reservoir Size. J Infect Dis. 2021 10 13; 224(7):1209-1218.
Stone M, Rosenbloom DIS, Bacchetti P, Deng X, Dimapasoc M, Keating S, Bakkour S, Richman DD, Mellors JW, Deeks SG, Lai J, Beg S, Siliciano JD, Pagliuzza A, Chomont N, Lackman-Smith C, Ptak RG, Busch MP. PMID: 32147687; PMCID: PMC8514180.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Impact of Anti-PD-1 and Anti-CTLA-4 on the Human Immunodeficiency Virus (HIV) Reservoir in People Living With HIV With Cancer on Antiretroviral Therapy: The AIDS Malignancy Consortium 095 Study. Clin Infect Dis. 2021 10 05; 73(7):e1973-e1981.
Rasmussen TA, Rajdev L, Rhodes A, Dantanarayana A, Tennakoon S, Chea S, Spelman T, Lensing S, Rutishauser R, Bakkour S, Busch M, Siliciano JD, Siliciano RF, Einstein MH, Dittmer DP, Chiao E, Deeks SG, Durand C, Lewin SR. PMID: 33677480; PMCID: PMC8492152.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansCellsCTClinical Trials
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HIV-1 Genomes Are Enriched in Memory CD4+ T-Cells with Short Half-Lives. mBio. 2021 10 26; 12(5):e0244721.
Morcilla V, Bacchus-Souffan C, Fisher K, Horsburgh BA, Hiener B, Wang XQ, Schlub TE, Fitch M, Hoh R, Hecht FM, Martin JN, Deeks SG, Hellerstein MK, McCune JM, Hunt PW, Palmer S. PMID: 34544282; PMCID: PMC8546577.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
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SARS-CoV-2 serology across scales: a framework for unbiased seroprevalence estimation incorporating antibody kinetics and epidemic recency. medRxiv. 2021 Sep 14.
Takahashi S, Peluso MJ, Hakim J, Turcios K, Janson O, Routledge I, Busch MP, Hoh R, Tai V, Kelly JD, Martin JN, Deeks SG, Henrich TJ, Greenhouse B, Rodríguez-Barraquer I. PMID: 34545373; PMCID: PMC8452112.
View in:
PubMed Mentions:
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Towards access for all: 1st Working Group Report for the Global Gene Therapy Initiative (GGTI). Gene Ther. 2023 04; 30(3-4):216-221.
Adair JE, Androski L, Bayigga L, Bazira D, Brandon E, Dee L, Deeks S, Draz M, Dubé K, Dybul M, Gurkan U, Harlow E, Kityo C, Louella M, Malik P, Mathews V, McKemey A, Mugerwa H, Muyanja D, Olayiwola O, Orentas RJ, Popovski A, Sheehy J, Ssali F, Nsubuga MS, Tisdale JF, Verhoeyen E, Dropulic B. PMID: 34493840; PMCID: PMC10113145.
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PubMed Mentions:
8 Fields:
Translation:
Humans
-
Functional impairment of HIV-specific CD8+ T cells precedes aborted spontaneous control of viremia. Immunity. 2021 10 12; 54(10):2372-2384.e7.
Collins DR, Urbach JM, Racenet ZJ, Arshad U, Power KA, Newman RM, Mylvaganam GH, Ly NL, Lian X, Rull A, Rassadkina Y, Yanez AG, Peluso MJ, Deeks SG, Vidal F, Lichterfeld M, Yu XG, Gaiha GD, Allen TM, Walker BD. PMID: 34496223; PMCID: PMC8516715.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
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HIV Antibody Profiles in HIV Controllers and Persons With Treatment-Induced Viral Suppression. Front Immunol. 2021; 12:740395.
Kammers K, Chen A, Monaco DR, Hudelson SE, Grant-McAuley W, Moore RD, Alter G, Deeks SG, Morrison CS, Eller LA, Blankson JN, Laeyendecker O, Ruczinski I, Eshleman SH, Larman HB. PMID: 34512672; PMCID: PMC8428532.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms. Cell Rep. 2021 08 10; 36(6):109518.
Peluso MJ, Deitchman AN, Torres L, Iyer NS, Munter SE, Nixon CC, Donatelli J, Thanh C, Takahashi S, Hakim J, Turcios K, Janson O, Hoh R, Tai V, Hernandez Y, Fehrman EA, Spinelli MA, Gandhi M, Trinh L, Wrin T, Petropoulos CJ, Aweeka FT, Rodriguez-Barraquer I, Kelly JD, Martin JN, Deeks SG, Greenhouse B, Rutishauser RL, Henrich TJ. PMID: 34358460; PMCID: PMC8342976.
View in:
PubMed Mentions:
109 Fields:
Translation:
HumansCells
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SARS-CoV-2 Vaccination in the Context of Ongoing HIV Cure-Related Research Studies. J Acquir Immune Defic Syndr. 2021 08 01; 87(4):e232-e233.
Peluso MJ, Dee L, Taylor J, Campbell DM, Ehm A, Agosto-Rosario M, Shao S, Williams MC, Hoh R, Rutishauser RL, Deeks SG, Sauceda JA, Dubé K. PMID: 33852502; PMCID: PMC8217209.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansPHPublic Health
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SARS-CoV-2 antibody magnitude and detectability are driven by disease severity, timing, and assay. Sci Adv. 2021 Jul; 7(31).
Peluso MJ, Takahashi S, Hakim J, Kelly JD, Torres L, Iyer NS, Turcios K, Janson O, Munter SE, Thanh C, Donatelli J, Nixon CC, Hoh R, Tai V, Fehrman EA, Hernandez Y, Spinelli MA, Gandhi M, Palafox MA, Vallari A, Rodgers MA, Prostko J, Hackett J, Trinh L, Wrin T, Petropoulos CJ, Chiu CY, Norris PJ, DiGermanio C, Stone M, Busch MP, Elledge SK, Zhou XX, Wells JA, Shu A, Kurtz TW, Pak JE, Wu W, Burbelo PD, Cohen JI, Rutishauser RL, Martin JN, Deeks SG, Henrich TJ, Rodriguez-Barraquer I, Greenhouse B. PMID: 34330709; PMCID: PMC8324059.
View in:
PubMed Mentions:
93 Fields:
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Discordant Virus-Specific Antibody Levels, Antibody Neutralization Capacity, and T-cell Responses Following 3 Doses of SARS-CoV-2 Vaccination in a Patient With Connective Tissue Disease. Open Forum Infect Dis. 2021 Aug; 8(8):ofab393.
Peluso MJ, Munter SE, Lynch KL, Yun C, Torres L, Iyer NS, Donatelli J, Ryan L, Deitchman AN, Deeks SG, Rutishauser RL, Henrich TJ. PMID: 34395717; PMCID: PMC8344490.
View in:
PubMed Mentions:
2
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The TLR7 agonist vesatolimod induced a modest delay in viral rebound in HIV controllers after cessation of antiretroviral therapy. Sci Transl Med. 2021 06 23; 13(599).
SenGupta D, Brinson C, DeJesus E, Mills A, Shalit P, Guo S, Cai Y, Wallin JJ, Zhang L, Humeniuk R, Begley R, Geleziunas R, Mellors J, Wrin T, Jones N, Milush J, Ferre AL, Shacklett BL, Laird GM, Moldt B, Vendrame E, Brainard DM, Ramgopal M, Deeks SG. PMID: 34162752.
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Abnormal Levels of Some Biomarkers of Immune Activation Despite Very Early Treatment of Human Immunodeficiency Virus. J Infect Dis. 2021 05 20; 223(9):1621-1630.
Schnittman SR, Deitchman AN, Beck-Engeser G, Ahn H, York VA, Hartig H, Hecht FM, Martin JN, Deeks SG, Aweeka FT, Hunt PW. PMID: 32915986; PMCID: PMC8136975.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Operationalizing Human Immunodeficiency Virus Cure-related Trials with Analytic Treatment Interruptions During the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Pandemic: A Collaborative Approach. Clin Infect Dis. 2021 05 18; 72(10):1843-1849.
Peluso MJ, Dee L, Shao S, Taylor J, Campbell D, Collins S, Gandhi M, Johnston R, Deeks SG, Sauceda JA, Dubé K. PMID: 32841311; PMCID: PMC7499539.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCellsPHPublic Health
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multiSero: open multiplex-ELISA platform for analyzing antibody responses to SARS-CoV-2 infection. medRxiv. 2021 May 11.
Byrum JR, Waltari E, Janson O, Guo SM, Folkesson J, Chhun BB, Vinden J, Ivanov IE, Forst ML, Li H, Larson AG, Wu W, Tato CM, McCutcheon KM, Peluso MJ, Henrich TJ, Deeks SG, Prakash M, Greenhouse B, Pak JE, Mehta SB. PMID: 34013298; PMCID: PMC8132273.
View in:
PubMed Mentions:
1
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Brief Report: Lower Socioeconomic Status Associates With Greater Systemic and Arterial Inflammation in HIV. J Acquir Immune Defic Syndr. 2021 05 01; 87(1):706-710.
Zhang L, Abohashem S, Osborne MT, Naddaf N, Park R, Moore K, Patrich T, Deeks SG, Hsue PY, Tawakol AA. PMID: 33492022; PMCID: PMC8026700.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Short Communication: A Pilot Study of the Effects of Losartan Versus Placebo on Pneumoproteins in HIV: A Secondary Analysis of a Randomized Double Blind Study. AIDS Res Hum Retroviruses. 2022 02; 38(2):127-130.
MacDonald DM, Collins G, Wendt CH, Wolfson J, Tracy RP, Rhame F, Deeks S, Rizza SA, Temesgen Z, Morse C, Liappis AP, Sereti I, Baker JV, Kunisaki KM. PMID: 33749317; PMCID: PMC8861910.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
CpG Methylation Profiles of HIV-1 Pro-Viral DNA in Individuals on ART. Viruses. 2021 04 29; 13(5).
Boltz VF, Ceriani C, Rausch JW, Shao W, Bale MJ, Keele BF, Hoh R, Milush JM, Deeks SG, Maldarelli F, Kearney MF, Coffin JM. PMID: 33946976; PMCID: PMC8146454.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Characterization of HIV-induced remodeling reveals differences in infection susceptibility of memory CD4+ T cell subsets in vivo. Cell Rep. 2021 04 27; 35(4):109038.
Xie G, Luo X, Ma T, Frouard J, Neidleman J, Hoh R, Deeks SG, Greene WC, Roan NR. PMID: 33910003; PMCID: PMC8202093.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
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A highly multiplexed droplet digital PCR assay to measure the intact HIV-1 proviral reservoir. Cell Rep Med. 2021 04 20; 2(4):100243.
Levy CN, Hughes SM, Roychoudhury P, Reeves DB, Amstuz C, Zhu H, Huang ML, Wei Y, Bull ME, Cassidy NAJ, McClure J, Frenkel LM, Stone M, Bakkour S, Wonderlich ER, Busch MP, Deeks SG, Schiffer JT, Coombs RW, Lehman DA, Jerome KR, Hladik F. PMID: 33948574; PMCID: PMC8080125.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCells
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Characterizing the COVID-19 illness experience to inform the study of post-acute sequelae and recovery: a qualitative study. medRxiv. 2021 Mar 24.
Santiago-Rodriguez EI, Maiorana A, Peluso MJ, Hoh R, Tai V, Fehrman EA, Hernandez Y, Torres L, Spinelli MA, Gandhi M, Kelly JD, Martin JN, Henrich TJ, Deeks SG, Sauceda JA. PMID: 33758881; PMCID: PMC7987040.
View in:
PubMed Mentions:
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Losartan to reduce inflammation and fibrosis endpoints in HIV disease. AIDS. 2021 03 15; 35(4):575-583.
Baker JV, Wolfson J, Collins G, Morse C, Rhame F, Liappis AP, Rizza S, Temesgen Z, Mystakelis H, Deeks S, Neaton J, Schacker T, Sereti I, Tracy RP. PMID: 33252490; PMCID: PMC8062089.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Rapid implementation of a cohort for the study of post-acute sequelae of SARS-CoV-2 infection/COVID-19. medRxiv. 2021 Mar 12.
Peluso MJ, Kelly JD, Lu S, Goldberg SA, Davidson MC, Mathur S, Durstenfeld MS, Spinelli MA, Hoh R, Tai V, Fehrman EA, Torres L, Hernandez Y, Williams MC, Arreguin MI, Bautista JA, Ngo LH, Deswal M, Munter SE, Martinez EO, Anglin KA, Romero MD, Tavs J, Rugart PR, Chen JY, Sans HM, Murray VW, Ellis PK, Donohue KC, Massachi JA, Weiss JO, Mehdi I, Pineda-Ramirez J, Tang AF, Wenger M, Assenzio M, Yuan Y, Krone M, Rutishauser RL, Rodriguez-Barraquer I, Greenhouse B, Sauceda JA, Gandhi M, Hsue PY, Henrich TJ, Deeks SG, Martin JN. PMID: 33758895; PMCID: PMC7987054.
View in:
PubMed Mentions:
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SARS-CoV-2 antibody magnitude and detectability are driven by disease severity, timing, and assay. medRxiv. 2021 Mar 05.
Peluso MJ, Takahashi S, Hakim J, Kelly JD, Torres L, Iyer NS, Turcios K, Janson O, Munter SE, Thanh C, Nixon CC, Hoh R, Tai V, Fehrman EA, Hernandez Y, Spinelli MA, Gandhi M, Palafox MA, Vallari A, Rodgers MA, Prostko J, Hackett J, Trinh L, Wrin T, Petroplolous CJ, Chiu CY, Norris PJ, DiGermanio C, Stone M, Busch MP, Elledge SK, Zhou XX, Wells JA, Shu A, Kurtz TW, Pak JE, Wu W, Burbelo PD, Cohen JI, Rutishauser RL, Martin JN, Deeks SG, Henrich TJ, Rodriguez-Barraquer I, Greenhouse B. PMID: 33688675; PMCID: PMC7941652.
View in:
PubMed Mentions:
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Long-Term SARS-CoV-2-Specific Immune and Inflammatory Responses Across a Clinically Diverse Cohort of Individuals Recovering from COVID-19. medRxiv. 2021 Mar 01.
Peluso MJ, Deitchman AN, Torres L, Iyer NS, Nixon CC, Munter SE, Donatelli J, Thanh C, Takahashi S, Hakim J, Turcios K, Janson O, Hoh R, Tai V, Hernandez Y, Fehrman E, Spinelli MA, Gandhi M, Trinh L, Wrin T, Petropoulos CJ, Aweeka FT, Rodriguez-Barraquer I, Kelly JD, Martin JN, Deeks SG, Greenhouse B, Rutishauser RL, Henrich TJ. PMID: 33688685; PMCID: PMC7941662.
View in:
PubMed Mentions:
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Multiply spliced HIV RNA is a predictive measure of virus production ex vivo and in vivo following reversal of HIV latency. EBioMedicine. 2021 Mar; 65:103241.
Zerbato JM, Khoury G, Zhao W, Gartner MJ, Pascoe RD, Rhodes A, Dantanarayana A, Gooey M, Anderson J, Bacchetti P, Deeks SG, McMahon J, Roche M, Rasmussen TA, Purcell DF, Lewin SR. PMID: 33647768; PMCID: PMC7920823.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Participant Perspectives and Experiences Entering an Intensively Monitored Antiretroviral Pause: Results from the AIDS Clinical Trials Group A5345 Biomarker Study. AIDS Res Hum Retroviruses. 2021 06; 37(6):489-501.
Diepstra KL, Barr L, Palm D, Hogg E, Mollan KR, Henley L, Stover AM, Simoni JM, Sugarman J, Brown B, Sauceda JA, Deeks S, Fox L, Gandhi RT, Smith D, Li JZ, Dubé K. PMID: 33472545; PMCID: PMC8213012.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
-
Characterization and Biomarker Analyses of Post-COVID-19 Complications and Neurological Manifestations. Cells. 2021 02 13; 10(2).
Sun B, Tang N, Peluso MJ, Iyer NS, Torres L, Donatelli JL, Munter SE, Nixon CC, Rutishauser RL, Rodriguez-Barraquer I, Greenhouse B, Kelly JD, Martin JN, Deeks SG, Henrich TJ, Pulliam L. PMID: 33668514; PMCID: PMC7918597.
View in:
PubMed Mentions:
93 Fields:
Translation:
HumansCells
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TCF-1 regulates HIV-specific CD8+ T cell expansion capacity. JCI Insight. 2021 02 08; 6(3).
Rutishauser RL, Deguit CDT, Hiatt J, Blaeschke F, Roth TL, Wang L, Raymond KA, Starke CE, Mudd JC, Chen W, Smullin C, Matus-Nicodemos R, Hoh R, Krone M, Hecht FM, Pilcher CD, Martin JN, Koup RA, Douek DC, Brenchley JM, Sékaly RP, Pillai SK, Marson A, Deeks SG, McCune JM, Hunt PW. PMID: 33351785; PMCID: PMC7934879.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansAnimalsCells
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Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity Ex Vivo and In Vivo. J Virol. 2021 03 25; 95(8).
Gramatica A, Schwarzer R, Brantley W, Varco-Merth B, Sperber HS, Hull PA, Montano M, Migueles SA, Rosenthal D, Hogan LE, Johnson JR, Packard TA, Grimmett ZW, Herzig E, Besnard E, Nekorchuk M, Hsiao F, Deeks SG, Snape M, Kiernan B, Roan NR, Lifson JD, Estes JD, Picker LJ, Verdin E, Krogan NJ, Henrich TJ, Connors M, Ott M, Pillai SK, Okoye AA, Greene WC. PMID: 33536176; PMCID: PMC8103695.
View in:
PubMed Mentions:
10 Fields:
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Persistent COVID-19-associated neurocognitive symptoms in non-hospitalized patients. J Neurovirol. 2021 02; 27(1):191-195.
Hellmuth J, Barnett TA, Asken BM, Kelly JD, Torres L, Stephens ML, Greenhouse B, Martin JN, Chow FC, Deeks SG, Greene M, Miller BL, Annan W, Henrich TJ, Peluso MJ. PMID: 33528824; PMCID: PMC7852463.
View in:
PubMed Mentions:
66 Fields:
Translation:
HumansCells
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Antigen-driven clonal selection shapes the persistence of HIV-1-infected CD4+ T cells in vivo. J Clin Invest. 2021 02 01; 131(3).
Simonetti FR, Zhang H, Soroosh GP, Duan J, Rhodehouse K, Hill AL, Beg SA, McCormick K, Raymond HE, Nobles CL, Everett JK, Kwon KJ, White JA, Lai J, Margolick JB, Hoh R, Deeks SG, Bushman FD, Siliciano JD, Siliciano RF. PMID: 33301425; PMCID: PMC7843227.
View in:
PubMed Mentions:
86 Fields:
Translation:
HumansCells
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Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART. PLoS Pathog. 2021 01; 17(1):e1009214.
Bacchus-Souffan C, Fitch M, Symons J, Abdel-Mohsen M, Reeves DB, Hoh R, Stone M, Hiatt J, Kim P, Chopra A, Ahn H, York VA, Cameron DL, Hecht FM, Martin JN, Yukl SA, Mallal S, Cameron PU, Deeks SG, Schiffer JT, Lewin SR, Hellerstein MK, McCune JM, Hunt PW. PMID: 33465157; PMCID: PMC7846027.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCells
-
Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19. J Leukoc Biol. 2021 07; 110(1):21-26.
Corley MJ, Pang APS, Dody K, Mudd PA, Patterson BK, Seethamraju H, Bram Y, Peluso MJ, Torres L, Iyer NS, Premeaux TA, Yeung ST, Chandar V, Borczuk A, Schwartz RE, Henrich TJ, Deeks SG, Sacha JB, Ndhlovu LC. PMID: 33464637; PMCID: PMC8013321.
View in:
PubMed Mentions:
61 Fields:
Translation:
HumansCells
-
NIH Workshop on HIV-Associated Comorbidities, Coinfections, and Complications: Summary and Recommendation for Future Research. J Acquir Immune Defic Syndr. 2021 01 01; 86(1):11-18.
Pahwa S, Deeks S, Zou S, Tomitch N, Miller-Novak L, Caler E, Justice A, Sacktor N, Gabuzda D, Hunt PW, Brown T, Kurth A, Baral S, Mugavero M, Mayer KH, Mendenhall E, Detels R, Mutabazi V. PMID: 33306561; PMCID: PMC7982002.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
Accumulation of HIV-1 Drug Resistance Mutations and Methamphetamine Use. Curr HIV Res. 2021; 19(6):497-503.
Truong HM, Fatch R, Deeks SG, Krone M, Martin JN, Hunt PW, Lum PJ. PMID: 34176462; PMCID: PMC10659984.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
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Shared Mechanisms Govern HIV Transcriptional Suppression in Circulating CD103+ and Gut CD4+ T Cells. J Virol. 2020 12 22; 95(2).
Yukl SA, Khan S, Chen TH, Trapecar M, Wu F, Xie G, Telwatte S, Fulop D, Pico AR, Laird GM, Ritter KD, Jones NG, Lu CM, Siliciano RF, Roan NR, Milush JM, Somsouk M, Deeks SG, Hunt PW, Sanjabi S. PMID: 33115867; PMCID: PMC7944458.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
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HIV cure research in the time of COVID-19 - Antiretroviral therapy treatment interruption trials: A discussion paper. J Virus Erad. 2021 Mar; 7(1):100025.
Fidler S, Lewin S, Deeks S, Sogaard OS, Vanderkerckhove L, Collins S, Kelly D, Singh J, Caskey M, Frater J. PMID: 33312681; PMCID: PMC7719279.
View in:
PubMed Mentions:
5
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The case for an HIV cure and how to get there. Lancet HIV. 2021 01; 8(1):e51-e58.
Dybul M, Attoye T, Baptiste S, Cherutich P, Dabis F, Deeks SG, Dieffenbach C, Doehle B, Goodenow MM, Jiang A, Kemps D, Lewin SR, Lumpkin MM, Mathae L, McCune JM, Ndung'u T, Nsubuga M, Peay HL, Pottage J, Warren M, Sikazwe I, Sunnylands 2019 Working Group. PMID: 33271124; PMCID: PMC7773626.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCells
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Multi-stakeholder consensus on a target product profile for an HIV cure. Lancet HIV. 2021 01; 8(1):e42-e50.
Lewin SR, Attoye T, Bansbach C, Doehle B, Dubé K, Dybul M, SenGupta D, Jiang A, Johnston R, Lamplough R, McCune JM, Nabel GJ, Ndung'u T, Pottage J, Ripin D, Rooney JF, Sikazwe I, Nsubuga M, Warren M, Deeks SG, Sunnylands 2019 Working Group. PMID: 33271125; PMCID: PMC7773628.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansCellsPHPublic Health
-
Replicate Aptima Assay for Quantifying Residual Plasma Viremia in Individuals on Antiretroviral Therapy. J Clin Microbiol. 2020 11 18; 58(12).
Bakkour S, Deng X, Bacchetti P, Grebe E, Montalvo L, Worlock A, Stone M, Deeks SG, Richman DD, Busch MP. PMID: 32967900; PMCID: PMC7685884.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Mechanistic differences underlying HIV latency in the gut and blood contribute to differential responses to latency-reversing agents. AIDS. 2020 11 15; 34(14):2013-2024.
Telwatte S, Kim P, Chen TH, Milush JM, Somsouk M, Deeks SG, Hunt PW, Wong JK, Yukl SA. PMID: 32910065; PMCID: PMC7990078.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Maintenance of Viral Suppression in Human Immunodeficiency Virus Controllers Despite Waning T-Cell Responses During Antiretroviral Therapy. J Infect Dis. 2020 11 09; 222(11):1837-1842.
Jilg N, Garcia-Broncano P, Peluso M, Segal FP, Bosch RJ, Roberts-Toler C, Chen SMY, Van Dam CN, Keefer MC, Kuritzkes DR, Landay AL, Deeks S, Yu XG, Sax PE, Li JZ, AIDS Clinical Trials Group A5308 Study Team. PMID: 32496516; PMCID: PMC7896274.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Universal Polymerase Chain Reaction and Antibody Testing Demonstrate Little to No Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 in a Rural Community. Open Forum Infect Dis. 2021 Jan; 8(1):ofaa531.
Appa A, Takahashi S, Rodriguez-Barraquer I, Chamie G, Sawyer A, Duarte E, Hakim J, Turcios K, Vinden J, Janson O, Manglik A, Peluso MJ, Deeks SG, Henrich TJ, Torres L, Rodgers M, Hackett J, Chiu C, Havlir D, Greenhouse B. PMID: 34109255; PMCID: PMC7665736.
View in:
PubMed Mentions:
8
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HLA tapasin independence: broader peptide repertoire and HIV control. Proc Natl Acad Sci U S A. 2020 11 10; 117(45):28232-28238.
Bashirova AA, Viard M, Naranbhai V, Grifoni A, Garcia-Beltran W, Akdag M, Yuki Y, Gao X, O'hUigin C, Raghavan M, Wolinsky S, Bream JH, Duggal P, Martinson J, Michael NL, Kirk GD, Buchbinder SP, Haas D, Goedert JJ, Deeks SG, Fellay J, Walker B, Goulder P, Cresswell P, Elliott T, Sette A, Carlson J, Carrington M. PMID: 33097667; PMCID: PMC7668082.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansCells
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Mining for humoral correlates of HIV control and latent reservoir size. PLoS Pathog. 2020 10; 16(10):e1008868.
Das J, Devadhasan A, Linde C, Broge T, Sassic J, Mangano M, O'Keefe S, Suscovich T, Streeck H, Irrinki A, Pohlmeyer C, Min-Oo G, Lin S, Weiner JA, Cihlar T, Ackerman ME, Julg B, Deeks S, Lauffenburger DA, Alter G. PMID: 33048992; PMCID: PMC7553335.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Association of Viral Persistence and Atherosclerosis in Adults With Treated HIV Infection. JAMA Netw Open. 2020 10 01; 3(10):e2018099.
McLaughlin MM, Ma Y, Scherzer R, Rahalkar S, Martin JN, Mills C, Milush J, Deeks SG, Hsue PY. PMID: 33119103; PMCID: PMC7596582.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
-
Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir. Elife. 2020 09 29; 9.
Neidleman J, Luo X, Frouard J, Xie G, Hsiao F, Ma T, Morcilla V, Lee A, Telwatte S, Thomas R, Tamaki W, Wheeler B, Hoh R, Somsouk M, Vohra P, Milush J, James KS, Archin NM, Hunt PW, Deeks SG, Yukl SA, Palmer S, Greene WC, Roan NR. PMID: 32990219; PMCID: PMC7524554.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansCells
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The Current State of HIV and Aging: Findings Presented at the 10th International Workshop on HIV and Aging. AIDS Res Hum Retroviruses. 2020 12; 36(12):973-981.
Shiau S, Bender AA, O'Halloran JA, Sundermann E, Aggarwal J, Althoff KN, Baker JV, Deeks S, Fried LP, Karpiak S, Karris MY, Marcotte TD, Nachega JB, Margolick JB, Erlandson KM, Moore DJ. PMID: 32847368; PMCID: PMC7703090.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCellsPHPublic Health
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Everolimus, an mTORC1/2 inhibitor, in ART-suppressed individuals who received solid organ transplantation: A prospective study. Am J Transplant. 2021 05; 21(5):1765-1779.
Henrich TJ, Schreiner C, Cameron C, Hogan LE, Richardson B, Rutishauser RL, Deitchman AN, Chu S, Rogers R, Thanh C, Gibson EA, Zarinsefat A, Bakkour S, Aweeka F, Busch MP, Liegler T, Baker C, Milush J, Deeks SG, Stock PG. PMID: 32780519; PMCID: PMC9177122.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Filgotinib suppresses HIV-1-driven gene transcription by inhibiting HIV-1 splicing and T cell activation. J Clin Invest. 2020 09 01; 130(9):4969-4984.
Yeh YJ, Jenike KM, Calvi RM, Chiarella J, Hoh R, Deeks SG, Ho YC. PMID: 32573496; PMCID: PMC7456222.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Distinct viral reservoirs in individuals with spontaneous control of HIV-1. Nature. 2020 09; 585(7824):261-267.
Jiang C, Lian X, Gao C, Sun X, Einkauf KB, Chevalier JM, Chen SMY, Hua S, Rhee B, Chang K, Blackmer JE, Osborn M, Peluso MJ, Hoh R, Somsouk M, Milush J, Bertagnolli LN, Sweet SE, Varriale JA, Burbelo PD, Chun TW, Laird GM, Serrao E, Engelman AN, Carrington M, Siliciano RF, Siliciano JM, Deeks SG, Walker BD, Lichterfeld M, Yu XG. PMID: 32848246; PMCID: PMC7837306.
View in:
PubMed Mentions:
173 Fields:
Translation:
HumansCells
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Universal PCR and antibody testing demonstrate little to no transmission of SARS-CoV-2 in a rural community. medRxiv. 2020 Aug 17.
Appa A, Takahashi S, Rodriguez-Barraquer I, Chamie G, Sawyer A, Consortium C, Duarte E, Hakim J, Turcios K, Vinden J, Janson O, Manglik A, Peluso MJ, Deeks SG, Henrich TJ, Torres L, Rodgers M, Hackett J, Chiu C, Havlir D, Greenhouse B. PMID: 32839781; PMCID: PMC7444294.
View in:
PubMed Mentions:
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Intact proviral DNA assay analysis of large cohorts of people with HIV provides a benchmark for the frequency and composition of persistent proviral DNA. Proc Natl Acad Sci U S A. 2020 08 04; 117(31):18692-18700.
Simonetti FR, White JA, Tumiotto C, Ritter KD, Cai M, Gandhi RT, Deeks SG, Howell BJ, Montaner LJ, Blankson JN, Martin A, Laird GM, Siliciano RF, Mellors JW, Siliciano JD. PMID: 32690683; PMCID: PMC7414172.
View in:
PubMed Mentions:
50 Fields:
Translation:
HumansCells
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Delayed Expression of PD-1 and TIGIT on HIV-Specific CD8 T Cells in Untreated HLA-B*57:01 Individuals Followed from Early Infection. J Virol. 2020 07 01; 94(14).
Scharf L, Tauriainen J, Buggert M, Hartogensis W, Nolan DJ, Deeks SG, Salemi M, Hecht FM, Karlsson AC. PMID: 32350076; PMCID: PMC7343205.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCellsCTClinical Trials
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Longitudinal study reveals HIV-1-infected CD4+ T cell dynamics during long-term antiretroviral therapy. J Clin Invest. 2020 07 01; 130(7):3543-3559.
Antar AA, Jenike KM, Jang S, Rigau DN, Reeves DB, Hoh R, Krone MR, Keruly JC, Moore RD, Schiffer JT, Nonyane BA, Hecht FM, Deeks SG, Siliciano JD, Ho YC, Siliciano RF. PMID: 32191639; PMCID: PMC7324206.
View in:
PubMed Mentions:
58 Fields:
Translation:
HumansCellsCTClinical Trials
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Pathogenesis of Aging and Age-related Comorbidities in People with HIV: Highlights from the HIV ACTION Workshop. Pathog Immun. 2020; 5(1):143-174.
Gabuzda D, Jamieson BD, Collman RG, Lederman MM, Burdo TH, Deeks SG, Dittmer DP, Fox HS, Funderburg NT, Pahwa SG, Pandrea I, Wilson CC, Hunt PW. PMID: 32856008; PMCID: PMC7449259.
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PubMed Mentions:
26
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FOXO1 promotes HIV latency by suppressing ER stress in T cells. Nat Microbiol. 2020 09; 5(9):1144-1157.
Vallejo-Gracia A, Chen IP, Perrone R, Besnard E, Boehm D, Battivelli E, Tezil T, Krey K, Raymond KA, Hull PA, Walter M, Habrylo I, Cruz A, Deeks S, Pillai S, Verdin E, Ott M. PMID: 32541947; PMCID: PMC7483895.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
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The immune response fails to control HIV early in initial virus spread. J Clin Invest. 2020 06 01; 130(6):2803-2805.
Cohn LB, Deeks SG. PMID: 32338639; PMCID: PMC7259984.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Impact of first-line antiretroviral therapy regimens on the restoration of the CD4/CD8 ratio in the CNICS cohort. J Antimicrob Chemother. 2020 06 01; 75(6):1604-1610.
Herrera S, Fernandez-Felix BM, Hunt PW, Deeks SG, Sainz T, Heath SL, Achenbach CJ, Rodríguez B, Mathews C, Christopoulos K, Mayer K, Napravnik S, Moreno S, Serrano-Villar S. PMID: 32211777; PMCID: PMC7225872.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Single-cell transcriptional landscapes reveal HIV-1-driven aberrant host gene transcription as a potential therapeutic target. Sci Transl Med. 2020 05 13; 12(543).
Liu R, Yeh YJ, Varabyou A, Collora JA, Sherrill-Mix S, Talbot CC, Mehta S, Albrecht K, Hao H, Zhang H, Pollack RA, Beg SA, Calvi RM, Hu J, Durand CM, Ambinder RF, Hoh R, Deeks SG, Chiarella J, Spudich S, Douek DC, Bushman FD, Pertea M, Ho YC. PMID: 32404504; PMCID: PMC7453882.
View in:
PubMed Mentions:
58 Fields:
Translation:
HumansCells
-
'Rinse and Replace': Boosting T Cell Turnover To Reduce HIV-1 Reservoirs. Trends Immunol. 2020 06; 41(6):466-480.
Grossman Z, Singh NJ, Simonetti FR, Lederman MM, Douek DC, Deeks SG, Contributing authors. PMID: 32414695.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
-
Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection. PLoS Pathog. 2020 04; 16(4):e1008450.
Hsiao F, Frouard J, Gramatica A, Xie G, Telwatte S, Lee GQ, Roychoudhury P, Schwarzer R, Luo X, Yukl SA, Lee S, Hoh R, Deeks SG, Jones RB, Cavrois M, Greene WC, Roan NR. PMID: 32353080; PMCID: PMC7192375.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Association between statin use, atherosclerosis, and mortality in HIV-infected adults. PLoS One. 2020; 15(4):e0232636.
Phan BAP, Ma Y, Scherzer R, Deeks SG, Hsue PY. PMID: 32353062; PMCID: PMC7192415.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Antiretroviral Therapy Concentrations Differ in Gut vs. Lymph Node Tissues and Are Associated With HIV Viral Transcription by a Novel RT-ddPCR Assay. J Acquir Immune Defic Syndr. 2020 04 15; 83(5):530-537.
Lee SA, Telwatte S, Hatano H, Kashuba ADM, Cottrell ML, Hoh R, Liegler TJ, Stephenson S, Somsouk M, Hunt PW, Deeks SG, Yukl S, Savic RM. PMID: 32168200; PMCID: PMC7286563.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
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The Biology of the HIV-1 Latent Reservoir and Implications for Cure Strategies. Cell Host Microbe. 2020 04 08; 27(4):519-530.
Cohn LB, Chomont N, Deeks SG. PMID: 32272077; PMCID: PMC7219958.
View in:
PubMed Mentions:
117 Fields:
Translation:
HumansAnimalsCells
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High levels of genetically intact HIV in HLA-DR+ memory T cells indicates their value for reservoir studies. AIDS. 2020 04 01; 34(5):659-668.
Horsburgh BA, Lee E, Hiener B, Eden JS, Schlub TE, von Stockenstrom S, Odevall L, Milush JM, Liegler T, Sinclair E, Hoh R, Boritz EA, Douek DC, Fromentin R, Chomont N, Deeks SG, Hecht FM, Palmer S. PMID: 31913161; PMCID: PMC7071960.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCells
-
Editorial: HIV and Cancer Immunotherapy: Similar Challenges and Converging Approaches. Front Immunol. 2020; 11:519.
Paiardini M, Dhodapkar K, Harper J, Deeks SG, Ahmed R. PMID: 32296432; PMCID: PMC7138010.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes. Nat Immunol. 2020 05; 21(5):578-587.
Abdelsamed HA, Zebley CC, Nguyen H, Rutishauser RL, Fan Y, Ghoneim HE, Crawford JC, Alfei F, Alli S, Ribeiro SP, Castellaw AH, McGargill MA, Jin H, Boi SK, Speake C, Serti E, Turka LA, Busch ME, Stone M, Deeks SG, Sekaly RP, Zehn D, James EA, Nepom GT, Youngblood B. PMID: 32231298; PMCID: PMC7183435.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansAnimalsCells
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Circulating CD30+CD4+ T Cells Increase Before Human Immunodeficiency Virus Rebound After Analytical Antiretroviral Treatment Interruption. J Infect Dis. 2020 03 16; 221(7):1146-1155.
Prator CA, Thanh C, Kumar S, Pan T, Peluso MJ, Bosch R, Jones N, Milush JM, Bakkour S, Stone M, Busch MP, Deeks SG, Hunt PW, Henrich TJ. PMID: 31677350; PMCID: PMC7325710.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
-
Plasma tissue factor and immune activation are associated with carotid intima-media thickness progression in treated HIV infection. AIDS. 2020 03 15; 34(4):519-528.
Hsu DC, Ma YF, Narwan A, Rahalkar S, Rupert A, Scherzer R, Mills C, Deeks S, Sereti I, Hsue PY. PMID: 31634197.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
CXCR4-Using HIV Strains Predominate in Naive and Central Memory CD4+ T Cells in People Living with HIV on Antiretroviral Therapy: Implications for How Latency Is Established and Maintained. J Virol. 2020 02 28; 94(6).
Roche M, Tumpach C, Symons J, Gartner M, Anderson JL, Khoury G, Cashin K, Cameron PU, Churchill MJ, Deeks SG, Gorry PR, Lewin SR. PMID: 31852784; PMCID: PMC7158712.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Differential decay of intact and defective proviral DNA in HIV-1-infected individuals on suppressive antiretroviral therapy. JCI Insight. 2020 02 27; 5(4).
Peluso MJ, Bacchetti P, Ritter KD, Beg S, Lai J, Martin JN, Hunt PW, Henrich TJ, Siliciano JD, Siliciano RF, Laird GM, Deeks SG. PMID: 32045386; PMCID: PMC7101154.
View in:
PubMed Mentions:
102 Fields:
Translation:
HumansCells
-
Cerebrospinal fluid soluble CD30 elevation despite suppressive antiretroviral therapy in individuals living with HIV-1. J Virus Erad. 2020 Feb 20; 6(1):19-26.
Peluso MJ, Thanh C, Prator CA, Hogan LE, Arechiga VM, Stephenson S, Norris PJ, Di Germanio C, Fuchs D, Zetterberg H, Deeks SG, Gisslén M, Price RW, Henrich TJ. PMID: 32175087; PMCID: PMC7043898.
View in:
PubMed Mentions:
6
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A collaborative, multidisciplinary approach to HIV transmission risk mitigation during analytic treatment interruption. J Virus Erad. 2020 Feb 20; 6(1):34-37.
Peluso MJ, Dee L, Campbell D, Taylor J, Hoh R, Rutishauser RL, Sauceda J, Deeks SG, Dubé K. PMID: 32175090; PMCID: PMC7043899.
View in:
PubMed Mentions:
29
-
Human Immunodeficiency Virus (HIV)-Infected CCR6+ Rectal CD4+ T Cells and HIV Persistence On Antiretroviral Therapy. J Infect Dis. 2020 02 18; 221(5):744-755.
Anderson JL, Khoury G, Fromentin R, Solomon A, Chomont N, Sinclair E, Milush JM, Hartogensis W, Bacchetti P, Roche M, Tumpach C, Gartner M, Pitman MC, Epling CL, Hoh R, Hecht FM, Somsouk M, Cameron PU, Deeks SG, Lewin SR. PMID: 31796951; PMCID: PMC7026892.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCells
-
HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells. Nat Immunol. 2020 03; 21(3):274-286.
Wang Y, Lifshitz L, Gellatly K, Vinton CL, Busman-Sahay K, McCauley S, Vangala P, Kim K, Derr A, Jaiswal S, Kucukural A, McDonel P, Hunt PW, Greenough T, Houghton J, Somsouk M, Estes JD, Brenchley JM, Garber M, Deeks SG, Luban J. PMID: 32066947; PMCID: PMC7044076.
View in:
PubMed Mentions:
50 Fields:
Translation:
HumansCells
-
Different human resting memory CD4+ T cell subsets show similar low inducibility of latent HIV-1 proviruses. Sci Transl Med. 2020 01 29; 12(528).
Kwon KJ, Timmons AE, Sengupta S, Simonetti FR, Zhang H, Hoh R, Deeks SG, Siliciano JD, Siliciano RF. PMID: 31996465; PMCID: PMC7875249.
View in:
PubMed Mentions:
53 Fields:
Translation:
HumansCells
-
Impact of Antiretroviral Therapy Duration on HIV-1 Infection of T Cells within Anatomic Sites. J Virol. 2020 01 17; 94(3).
Lee E, von Stockenstrom S, Morcilla V, Odevall L, Hiener B, Shao W, Hartogensis W, Bacchetti P, Milush J, Liegler T, Sinclair E, Hatano H, Hoh R, Somsouk M, Hunt P, Boritz E, Douek D, Fromentin R, Chomont N, Deeks SG, Hecht FM, Palmer S. PMID: 31723024; PMCID: PMC7000983.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
-
Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8+ T cells. Sci Transl Med. 2019 12 18; 11(523).
Nguyen S, Deleage C, Darko S, Ransier A, Truong DP, Agarwal D, Japp AS, Wu VH, Kuri-Cervantes L, Abdel-Mohsen M, Del Rio Estrada PM, Ablanedo-Terrazas Y, Gostick E, Hoxie JA, Zhang NR, Naji A, Reyes-Terán G, Estes JD, Price DA, Douek DC, Deeks SG, Buggert M, Betts MR. PMID: 31852798; PMCID: PMC7265335.
View in:
PubMed Mentions:
57 Fields:
Translation:
HumansCells
-
Why and where an HIV cure is needed and how it might be achieved. Nature. 2019 12; 576(7787):397-405.
Ndung'u T, McCune JM, Deeks SG. PMID: 31853080; PMCID: PMC8052635.
View in:
PubMed Mentions:
69 Fields:
Translation:
HumansCells
-
Combined HIV-1 sequence and integration site analysis informs viral dynamics and allows reconstruction of replicating viral ancestors. Proc Natl Acad Sci U S A. 2019 12 17; 116(51):25891-25899.
Patro SC, Brandt LD, Bale MJ, Halvas EK, Joseph KW, Shao W, Wu X, Guo S, Murrell B, Wiegand A, Spindler J, Raley C, Hautman C, Sobolewski M, Fennessey CM, Hu WS, Luke B, Hasson JM, Niyongabo A, Capoferri AA, Keele BF, Milush J, Hoh R, Deeks SG, Maldarelli F, Hughes SH, Coffin JM, Rausch JW, Mellors JW, Kearney MF. PMID: 31776247; PMCID: PMC6925994.
View in:
PubMed Mentions:
58 Fields:
Translation:
HumansCells
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Differentiation into an Effector Memory Phenotype Potentiates HIV-1 Latency Reversal in CD4+ T Cells. J Virol. 2019 12 15; 93(24).
Kulpa DA, Talla A, Brehm JH, Ribeiro SP, Yuan S, Bebin-Blackwell AG, Miller M, Barnard R, Deeks SG, Hazuda D, Chomont N, Sékaly RP. PMID: 31578289; PMCID: PMC6880164.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansCells
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Author Correction: CCR5AS lncRNA variation differentially regulates CCR5, influencing HIV disease outcome. Nat Immunol. 2019 Nov; 20(11):1555.
Kulkarni S, Lied A, Kulkarni V, Rucevic M, Martin MP, Walker-Sperling V, Anderson SK, Ewy R, Singh S, Nguyen H, McLaren PJ, Viard M, Naranbhai V, Zou C, Lin Z, Gatanaga H, Oka S, Takiguchi M, Thio CL, Margolick J, Kirk GD, Goedert JJ, Hoots WK, Deeks SG, Haas DW, Michael N, Walker B, Le Gall S, Chowdhury FZ, Yu XG, Carrington M. PMID: 31548709.
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PubMed Mentions: Fields:
-
Attacking Latent HIV with convertibleCAR-T Cells, a Highly Adaptable Killing Platform. Cell. 2019 10 31; 179(4):880-894.e10.
Herzig E, Kim KC, Packard TA, Vardi N, Schwarzer R, Gramatica A, Deeks SG, Williams SR, Landgraf K, Killeen N, Martin DW, Weinberger LS, Greene WC. PMID: 31668804; PMCID: PMC6922308.
View in:
PubMed Mentions:
57 Fields:
Translation:
HumansAnimalsCells
-
Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals. PLoS Pathog. 2019 10; 15(10):e1008074.
Wonderlich ER, Subramanian K, Cox B, Wiegand A, Lackman-Smith C, Bale MJ, Stone M, Hoh R, Kearney MF, Maldarelli F, Deeks SG, Busch MP, Ptak RG, Kulpa DA. PMID: 31609991; PMCID: PMC6812841.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCells
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Some Aspects of CD8+ T-Cell Exhaustion Are Associated With Altered T-Cell Mitochondrial Features and ROS Content in HIV Infection. J Acquir Immune Defic Syndr. 2019 10 01; 82(2):211-219.
Deguit CDT, Hough M, Hoh R, Krone M, Pilcher CD, Martin JN, Deeks SG, McCune JM, Hunt PW, Rutishauser RL. PMID: 31513075; PMCID: PMC6746248.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
-
Memory CD4 + T-Cells Expressing HLA-DR Contribute to HIV Persistence During Prolonged Antiretroviral Therapy. Front Microbiol. 2019; 10:2214.
Lee E, Bacchetti P, Milush J, Shao W, Boritz E, Douek D, Fromentin R, Liegler T, Hoh R, Deeks SG, Hecht FM, Chomont N, Palmer S. PMID: 31611857; PMCID: PMC6775493.
View in:
PubMed Mentions:
29
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Statistical analysis of single-copy assays when some observations are zero. J Virus Erad. 2019 Sep 18; 5(3):167-173.
Bacchetti P, Bosch RJ, Scully EP, Deng X, Busch MP, Deeks SG, Lewin SR. PMID: 31700665; PMCID: PMC6816121.
View in:
PubMed Mentions:
4
-
HIV elite control is associated with reduced TRAILshort expression. AIDS. 2019 09 01; 33(11):1757-1763.
Paim AC, Cummins NW, Natesampillai S, Garcia-Rivera E, Kogan N, Neogi U, Sönnerborg A, Sperk M, Bren GD, Deeks S, Polley E, Badley AD. PMID: 31149947; PMCID: PMC6873462.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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HIV-Specific T Cell Responses Are Highly Stable on Antiretroviral Therapy. Mol Ther Methods Clin Dev. 2019 Dec 13; 15:9-17.
Xu Y, Trumble IM, Warren JA, Clutton G, Abad-Fernandez M, Kirchnerr J, Adimora AA, Deeks SG, Margolis DM, Kuruc JD, Gay CL, Archin NM, Mollan KR, Hudgens M, Goonetilleke N. PMID: 31534983; PMCID: PMC6745511.
View in:
PubMed Mentions:
16
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HIV-1 in lymph nodes is maintained by cellular proliferation during antiretroviral therapy. J Clin Invest. 2019 07 30; 129(11):4629-4642.
McManus WR, Bale MJ, Spindler J, Wiegand A, Musick A, Patro SC, Sobolewski MD, Musick VK, Anderson EM, Cyktor JC, Halvas EK, Shao W, Wells D, Wu X, Keele BF, Milush JM, Hoh R, Mellors JW, Hughes SH, Deeks SG, Coffin JM, Kearney MF. PMID: 31361603; PMCID: PMC6819093.
View in:
PubMed Mentions:
59 Fields:
Translation:
HumansCellsCTClinical Trials
-
Risk to Nonparticipants in HIV Remission Studies With Treatment Interruption: A Symposium. J Infect Dis. 2019 07 02; 220(220 Suppl 1):S1-S4.
Eyal N, Deeks SG. PMID: 31264687; PMCID: PMC6603969.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
-
How Unavoidable Are Analytical Treatment Interruptions in HIV Cure-Related Studies? J Infect Dis. 2019 07 02; 220(220 Suppl 1):S24-S26.
Margolis DM, Deeks SG. PMID: 31264691; PMCID: PMC6636248.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
CCR5AS lncRNA variation differentially regulates CCR5, influencing HIV disease outcome. Nat Immunol. 2019 07; 20(7):824-834.
Kulkarni S, Lied A, Kulkarni V, Rucevic M, Martin MP, Walker-Sperling V, Anderson SK, Ewy R, Singh S, Nguyen H, McLaren PJ, Viard M, Naranbhai V, Zou C, Lin Z, Gatanaga H, Oka S, Takiguchi M, Thio CL, Margolick J, Kirk GD, Goedert JJ, Hoots WK, Deeks SG, Haas DW, Michael N, Walker B, Le Gall S, Chowdhury FZ, Yu XG, Carrington M. PMID: 31209403; PMCID: PMC6584055.
View in:
PubMed Mentions:
46 Fields:
Translation:
HumansCells
-
Safety and Impact of Low-dose Methotrexate on Endothelial Function and Inflammation in Individuals With Treated Human Immunodeficiency Virus: AIDS Clinical Trials Group Study A5314. Clin Infect Dis. 2019 05 17; 68(11):1877-1886.
Hsue PY, Ribaudo HJ, Deeks SG, Bell T, Ridker PM, Fichtenbaum C, Daar ES, Havlir D, Yeh E, Tawakol A, Lederman M, Currier JS, Stein JH. PMID: 30219823; PMCID: PMC6522677.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCellsCTClinical Trials
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Unusual Cysteine Content in V1 Region of gp120 From an Elite Suppressor That Produces Broadly Neutralizing Antibodies. Front Immunol. 2019; 10:1021.
Hutchinson JM, Mesa KA, Alexander DL, Yu B, O'Rourke SM, Limoli KL, Wrin T, Deeks SG, Berman PW. PMID: 31156622; PMCID: PMC6530427.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Carnitine Is Associated With Atherosclerotic Risk and Myocardial Infarction in HIV -Infected Adults. J Am Heart Assoc. 2019 05 07; 8(9):e011037.
Sinha A, Ma Y, Scherzer R, Rahalkar S, Neilan BD, Crane H, Drozd D, Martin J, Deeks SG, Hunt P, Hsue PY. PMID: 31030595; PMCID: PMC6512101.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
CD32-RNA Co-localizes with HIV-RNA in CD3+ Cells Found within Gut Tissues from Viremic and ART-Suppressed Individuals. Pathog Immun. 2019; 4(1):147-160.
Vásquez JJ, Aguilar-Rodriguez BL, Rodriguez L, Hogan LE, Somsouk M, McCune JM, Deeks SG, Laszik ZG, Hunt PW, Henrich TJ. PMID: 31139759; PMCID: PMC6508427.
View in:
PubMed Mentions:
9
-
Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size. PLoS Comput Biol. 2019 04; 15(4):e1006849.
Rosenbloom DIS, Bacchetti P, Stone M, Deng X, Bosch RJ, Richman DD, Siliciano JD, Mellors JW, Deeks SG, Ptak RG, Hoh R, Keating SM, Dimapasoc M, Massanella M, Lai J, Sobolewski MD, Kulpa DA, Busch MP, Reservoir Assay Validation and Evaluation Network (RAVEN) Study Group. PMID: 30978183; PMCID: PMC6481870.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCells
-
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
-
Transcriptional down-regulation of ccr5 in a subset of HIV+ controllers and their family members. Elife. 2019 04 09; 8.
Gonzalo-Gil E, Rapuano PB, Ikediobi U, Leibowitz R, Mehta S, Coskun AK, Porterfield JZ, Lampkin TD, Marconi VC, Rimland D, Walker BD, Deeks S, Sutton RE. PMID: 30964004; PMCID: PMC6456299.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
-
Identification of NK Cell Subpopulations That Differentiate HIV-Infected Subject Cohorts with Diverse Levels of Virus Control. J Virol. 2019 04 01; 93(7).
Pohlmeyer CW, Gonzalez VD, Irrinki A, Ramirez RN, Li L, Mulato A, Murry JP, Arvey A, Hoh R, Deeks SG, Kukolj G, Cihlar T, Pflanz S, Nolan GP, Min-Oo G. PMID: 30700608; PMCID: PMC6430550.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCells
-
Emulating a trial of joint dynamic strategies: An application to monitoring and treatment of HIV-positive individuals. Stat Med. 2019 06 15; 38(13):2428-2446.
Caniglia EC, Robins JM, Cain LE, Sabin C, Logan R, Abgrall S, Mugavero MJ, Hernández-Díaz S, Meyer L, Seng R, Drozd DR, Seage Iii GR, Bonnet F, Le Marec F, Moore RD, Reiss P, van Sighem A, Mathews WC, Jarrín I, Alejos B, Deeks SG, Muga R, Boswell SL, Ferrer E, Eron JJ, Gill J, Pacheco A, Grinsztejn B, Napravnik S, Jose S, Phillips A, Justice A, Tate J, Bucher HC, Egger M, Furrer H, Miro JM, Casabona J, Porter K, Touloumi G, Crane H, Costagliola D, Saag M, Hernán MA. PMID: 30883859; PMCID: PMC6499640.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Recommendations for analytical antiretroviral treatment interruptions in HIV research trials-report of a consensus meeting. Lancet HIV. 2019 04; 6(4):e259-e268.
Julg B, Dee L, Ananworanich J, Barouch DH, Bar K, Caskey M, Colby DJ, Dawson L, Dong KL, Dubé K, Eron J, Frater J, Gandhi RT, Geleziunas R, Goulder P, Hanna GJ, Jefferys R, Johnston R, Kuritzkes D, Li JZ, Likhitwonnawut U, van Lunzen J, Martinez-Picado J, Miller V, Montaner LJ, Nixon DF, Palm D, Pantaleo G, Peay H, Persaud D, Salzwedel J, Salzwedel K, Schacker T, Sheikh V, Søgaard OS, Spudich S, Stephenson K, Sugarman J, Taylor J, Tebas P, Tiemessen CT, Tressler R, Weiss CD, Zheng L, Robb ML, Michael NL, Mellors JW, Deeks SG, Walker BD. PMID: 30885693; PMCID: PMC6688772.
View in:
PubMed Mentions:
110 Fields:
Translation:
Humans
-
Sex-Based Differences in Human Immunodeficiency Virus Type 1 Reservoir Activity and Residual Immune Activation. J Infect Dis. 2019 03 15; 219(7):1084-1094.
Scully EP, Gandhi M, Johnston R, Hoh R, Lockhart A, Dobrowolski C, Pagliuzza A, Milush JM, Baker CA, Girling V, Ellefson A, Gorelick R, Lifson J, Altfeld M, Alter G, Cedars M, Solomon A, Lewin SR, Karn J, Chomont N, Bacchetti P, Deeks SG. PMID: 30371873; PMCID: PMC6784502.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansCells
-
PD-1 blockade potentiates HIV latency reversal ex vivo in CD4+ T cells from ART-suppressed individuals. Nat Commun. 2019 02 18; 10(1):814.
Fromentin R, DaFonseca S, Costiniuk CT, El-Far M, Procopio FA, Hecht FM, Hoh R, Deeks SG, Hazuda DJ, Lewin SR, Routy JP, Sékaly RP, Chomont N. PMID: 30778080; PMCID: PMC6379401.
View in:
PubMed Mentions:
118 Fields:
Translation:
HumansCells
-
A quantitative approach for measuring the reservoir of latent HIV-1 proviruses. Nature. 2019 02; 566(7742):120-125.
Bruner KM, Wang Z, Simonetti FR, Bender AM, Kwon KJ, Sengupta S, Fray EJ, Beg SA, Antar AAR, Jenike KM, Bertagnolli LN, Capoferri AA, Kufera JT, Timmons A, Nobles C, Gregg J, Wada N, Ho YC, Zhang H, Margolick JB, Blankson JN, Deeks SG, Bushman FD, Siliciano JD, Laird GM, Siliciano RF. PMID: 30700913; PMCID: PMC6447073.
View in:
PubMed Mentions:
361 Fields:
Translation:
HumansCells
-
Reiterative Enrichment and Authentication of CRISPRi Targets (REACT) identifies the proteasome as a key contributor to HIV-1 latency. PLoS Pathog. 2019 01; 15(1):e1007498.
Li Z, Wu J, Chavez L, Hoh R, Deeks SG, Pillai SK, Zhou Q. PMID: 30645648; PMCID: PMC6333332.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansCells
-
Stimulant Use and Viral Suppression in the Era of Universal Antiretroviral Therapy. J Acquir Immune Defic Syndr. 2019 01 01; 80(1):89-93.
Carrico AW, Hunt PW, Neilands TB, Dilworth SE, Martin JN, Deeks SG, Riley ED. PMID: 30272634; PMCID: PMC6289664.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansCells
-
Unique Circulating MicroRNA Profiles in HIV Infection. J Acquir Immune Defic Syndr. 2018 12 15; 79(5):644-650.
Narla V, Bhakta N, Freedman JE, Tanriverdi K, Maka K, Deeks SG, Ganz P, Hsue P. PMID: 30204717.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
Transient loss of detectable HIV-1 RNA following brentuximab vedotin anti-CD30 therapy for Hodgkin lymphoma. Blood Adv. 2018 12 11; 2(23):3479-3482.
Wang CC, Thanh C, Gibson EA, Ball-Burack M, Hogan LE, Descours B, Jones N, Carvidi AB, Munter S, Bakkour S, Busch MP, Milush JM, Deeks SG, Henrich TJ. PMID: 30530753; PMCID: PMC6290106.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
IL-1β Inhibition Reduces Atherosclerotic Inflammation in HIV Infection. J Am Coll Cardiol. 2018 12 04; 72(22):2809-2811.
Hsue PY, Li D, Ma Y, Ishai A, Manion M, Nahrendorf M, Ganz P, Ridker PM, Deeks SG, Tawakol A. PMID: 30497570; PMCID: PMC8723182.
View in:
PubMed Mentions:
26 Fields:
Translation:
Humans
-
Gut and blood differ in constitutive blocks to HIV transcription, suggesting tissue-specific differences in the mechanisms that govern HIV latency. PLoS Pathog. 2018 11; 14(11):e1007357.
Telwatte S, Lee S, Somsouk M, Hatano H, Baker C, Kaiser P, Kim P, Chen TH, Milush J, Hunt PW, Deeks SG, Wong JK, Yukl SA. PMID: 30440043; PMCID: PMC6237391.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansCells
-
The Control of HIV After Antiretroviral Medication Pause (CHAMP) Study: Posttreatment Controllers Identified From 14 Clinical Studies. J Infect Dis. 2018 11 05; 218(12):1954-1963.
Namazi G, Fajnzylber JM, Aga E, Bosch RJ, Acosta EP, Sharaf R, Hartogensis W, Jacobson JM, Connick E, Volberding P, Skiest D, Margolis D, Sneller MC, Little SJ, Gianella S, Smith DM, Kuritzkes DR, Gulick RM, Mellors JW, Mehraj V, Gandhi RT, Mitsuyasu R, Schooley RT, Henry K, Tebas P, Deeks SG, Chun TW, Collier AC, Routy JP, Hecht FM, Walker BD, Li JZ. PMID: 30085241; PMCID: PMC6217727.
View in:
PubMed Mentions:
96 Fields:
Translation:
HumansCells
-
HIV control: Is getting there the same as staying there? PLoS Pathog. 2018 11; 14(11):e1007222.
Goulder P, Deeks SG. PMID: 30383857; PMCID: PMC6211749.
View in:
PubMed Mentions:
40 Fields:
Translation:
HumansAnimalsCells
-
Population Pharmacokinetics and Pharmacodynamics of Disulfiram on Inducing Latent HIV-1 Transcription in a Phase IIb Trial. Clin Pharmacol Ther. 2019 03; 105(3):692-702.
Lee SA, Elliott JH, McMahon J, Hartogenesis W, Bumpus NN, Lifson JD, Gorelick RJ, Bacchetti P, Deeks SG, Lewin SR, Savic RM. PMID: 30137649; PMCID: PMC6379104.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansCellsCTClinical Trials
-
Inconsistent HIV reservoir dynamics and immune responses following anti-PD-1 therapy in cancer patients with HIV infection. Ann Oncol. 2018 10 01; 29(10):2141-2142.
Scully EP, Rutishauser RL, Simoneau CR, Delagrèverie H, Euler Z, Thanh C, Li JZ, Hartig H, Bakkour S, Busch M, Alter G, Marty FM, Wang CC, Deeks SG, Lorch J, Henrich TJ. PMID: 30032204; PMCID: PMC6225895.
View in:
PubMed Mentions:
36 Fields:
Translation:
HumansCells
-
Variation in cell-associated unspliced HIV RNA on antiretroviral therapy is associated with the circadian regulator brain-and-muscle-ARNT-like-1. AIDS. 2018 09 24; 32(15):2119-2128.
Chang CC, Naranbhai V, Stern J, Roche M, Dantanarayana A, Ke R, Tennakoon S, Solomon A, Hoh R, Hartogensis W, Hecht FM, Sikaris K, Price DJ, Elliott JH, Deeks SG, Churchill M, Cameron PU, Hengartner N, Perelson AS, Lewin SR. PMID: 30005017; PMCID: PMC6173794.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCellsCTClinical Trials
-
Macrophage Activation Marker Soluble CD163 Is a Dynamic Marker of Liver Fibrogenesis in Human Immunodeficiency Virus/Hepatitis C Virus Coinfection. J Infect Dis. 2018 09 22; 218(9):1394-1403.
Lidofsky A, Holmes JA, Feeney ER, Kruger AJ, Salloum S, Zheng H, Seguin IS, Altinbas A, Masia R, Corey KE, Gustafson JL, Schaefer EA, Hunt PW, Deeks S, Somsouk M, Chew KW, Chung RT, Alatrakchi N. PMID: 29868909; PMCID: PMC6151081.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells
-
Ethical issues in HIV remission trials. Curr Opin HIV AIDS. 2018 09; 13(5):422-427.
Eyal N, Holtzman LG, Deeks SG. PMID: 30015634; PMCID: PMC6112842.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
-
Estrogen receptor-1 is a key regulator of HIV-1 latency that imparts gender-specific restrictions on the latent reservoir. Proc Natl Acad Sci U S A. 2018 08 14; 115(33):E7795-E7804.
Das B, Dobrowolski C, Luttge B, Valadkhan S, Chomont N, Johnston R, Bacchetti P, Hoh R, Gandhi M, Deeks SG, Scully E, Karn J. PMID: 30061382; PMCID: PMC6099847.
View in:
PubMed Mentions:
95 Fields:
Translation:
HumansCells
-
Maximising the global health impact of future HIV cure-related interventions through advance planning. J Virus Erad. 2018 Jul 01; 4(3):182-185.
Brown R, Deeks SG, Eyal N. PMID: 30050682; PMCID: PMC6038126.
View in:
PubMed Mentions:
2
-
Changes in Inflammation but Not in T-Cell Activation Precede Non-AIDS-Defining Events in a Case-Control Study of Patients on Long-term Antiretroviral Therapy. J Infect Dis. 2018 06 20; 218(2):239-248.
Angelidou K, Hunt PW, Landay AL, Wilson CC, Rodriguez B, Deeks SG, Bosch RJ, Lederman MM. PMID: 29309629; PMCID: PMC6009591.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
-
Identification and characterization of HIV-specific resident memory CD8+ T cells in human lymphoid tissue. Sci Immunol. 2018 06 01; 3(24).
Buggert M, Nguyen S, Salgado-Montes de Oca G, Bengsch B, Darko S, Ransier A, Roberts ER, Del Alcazar D, Brody IB, Vella LA, Beura L, Wijeyesinghe S, Herati RS, Del Rio Estrada PM, Ablanedo-Terrazas Y, Kuri-Cervantes L, Sada Japp A, Manne S, Vartanian S, Huffman A, Sandberg JK, Gostick E, Nadolski G, Silvestri G, Canaday DH, Price DA, Petrovas C, Su LF, Vahedi G, Dori Y, Frank I, Itkin MG, Wherry EJ, Deeks SG, Naji A, Reyes-Terán G, Masopust D, Douek DC, Betts MR. PMID: 29858286; PMCID: PMC6357781.
View in:
PubMed Mentions:
89 Fields:
Translation:
HumansAnimalsCells
-
A randomized, controlled trial of mindfulness-based stress reduction in HIV infection. Brain Behav Immun. 2018 10; 73:331-339.
Hecht FM, Moskowitz JT, Moran P, Epel ES, Bacchetti P, Acree M, Kemeny ME, Mendes WB, Duncan LG, Weng H, Levy JA, Deeks SG, Folkman S. PMID: 29842903; PMCID: PMC7656978.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
-
Distinct chromatin functional states correlate with HIV latency reactivation in infected primary CD4+ T cells. Elife. 2018 05 01; 7.
Battivelli E, Dahabieh MS, Abdel-Mohsen M, Svensson JP, Tojal Da Silva I, Cohn LB, Gramatica A, Deeks S, Greene WC, Pillai SK, Verdin E. PMID: 29714165; PMCID: PMC5973828.
View in:
PubMed Mentions:
94 Fields:
Translation:
HumansCells
-
Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease. PLoS Pathog. 2018 04; 14(4):e1006973.
Buggert M, Nguyen S, McLane LM, Steblyanko M, Anikeeva N, Paquin-Proulx D, Del Rio Estrada PM, Ablanedo-Terrazas Y, Noyan K, Reuter MA, Demers K, Sandberg JK, Eller MA, Streeck H, Jansson M, Nowak P, Sönnerborg A, Canaday DH, Naji A, Wherry EJ, Robb ML, Deeks SG, Reyes-Teran G, Sykulev Y, Karlsson AC, Betts MR. PMID: 29652923; PMCID: PMC5919077.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
-
Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1. J Clin Invest. 2018 05 01; 128(5):1903-1912.
Martin MP, Naranbhai V, Shea PR, Qi Y, Ramsuran V, Vince N, Gao X, Thomas R, Brumme ZL, Carlson JM, Wolinsky SM, Goedert JJ, Walker BD, Segal FP, Deeks SG, Haas DW, Migueles SA, Connors M, Michael N, Fellay J, Gostick E, Llewellyn-Lacey S, Price DA, Lafont BA, Pymm P, Saunders PM, Widjaja J, Wong SC, Vivian JP, Rossjohn J, Brooks AG, Carrington M. PMID: 29461980; PMCID: PMC5919796.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansCellsCTClinical Trials
-
Anti-Human Immunodeficiency Virus Antibodies in the Cerebrospinal Fluid: Evidence of Early Treatment Impact on Central Nervous System Reservoir? J Infect Dis. 2018 03 13; 217(7):1024-1032.
Burbelo PD, Price RW, Hagberg L, Hatano H, Spudich S, Deeks SG, Gisslén M. PMID: 29401308; PMCID: PMC5939835.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansCells
-
A20 upregulation during treated HIV disease is associated with intestinal epithelial cell recovery and function. PLoS Pathog. 2018 03; 14(3):e1006806.
Chitre AS, Kattah MG, Rosli YY, Pao M, Deswal M, Deeks SG, Hunt PW, Abdel-Mohsen M, Montaner LJ, Kim CC, Ma A, Somsouk M, McCune JM. PMID: 29505600; PMCID: PMC5854440.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
-
Increased HIV-1 transcriptional activity and infectious burden in peripheral blood and gut-associated CD4+ T cells expressing CD30. PLoS Pathog. 2018 02; 14(2):e1006856.
Hogan LE, Vasquez J, Hobbs KS, Hanhauser E, Aguilar-Rodriguez B, Hussien R, Thanh C, Gibson EA, Carvidi AB, Smith LCB, Khan S, Trapecar M, Sanjabi S, Somsouk M, Stoddart CA, Kuritzkes DR, Deeks SG, Henrich TJ. PMID: 29470552; PMCID: PMC5823470.
View in:
PubMed Mentions:
49 Fields:
Translation:
HumansCells
-
Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection. J Virol. 2018 02 15; 92(4).
Adland E, Hill M, Lavandier N, Csala A, Edwards A, Chen F, Radkowski M, Kowalska JD, Paraskevis D, Hatzakis A, Valenzuela-Ponce H, Pfafferott K, Williams I, Pellegrino P, Borrow P, Mori M, Rockstroh J, Prado JG, Mothe B, Dalmau J, Martinez-Picado J, Tudor-Williams G, Frater J, Stryhn A, Buus S, Teran GR, Mallal S, John M, Buchbinder S, Kirk G, Martin J, Michael N, Fellay J, Deeks S, Walker B, Avila-Rios S, Cole D, Brander C, Carrington M, Goulder P. PMID: 29167337; PMCID: PMC5790925.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
-
Viral protein Nef is detected in plasma of half of HIV-infected adults with undetectable plasma HIV RNA. PLoS One. 2018; 13(1):e0191613.
Ferdin J, Goricar K, Dolžan V, Plemenitaš A, Martin JN, Peterlin BM, Deeks SG, Lenassi M. PMID: 29364927; PMCID: PMC5783402.
View in:
PubMed Mentions:
50 Fields:
Translation:
Humans
-
Differential Expression of CD8+ T Cell Cytotoxic Effector Molecules in Blood and Gastrointestinal Mucosa in HIV-1 Infection. J Immunol. 2018 03 01; 200(5):1876-1888.
Kiniry BE, Hunt PW, Hecht FM, Somsouk M, Deeks SG, Shacklett BL. PMID: 29352005; PMCID: PMC5821568.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells
-
Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells. Science. 2018 01 05; 359(6371):86-90.
Ramsuran V, Naranbhai V, Horowitz A, Qi Y, Martin MP, Yuki Y, Gao X, Walker-Sperling V, Del Prete GQ, Schneider DK, Lifson JD, Fellay J, Deeks SG, Martin JN, Goedert JJ, Wolinsky SM, Michael NL, Kirk GD, Buchbinder S, Haas D, Ndung'u T, Goulder P, Parham P, Walker BD, Carlson JM, Carrington M. PMID: 29302013; PMCID: PMC5933048.
View in:
PubMed Mentions:
90 Fields:
Translation:
HumansCells
-
The end of HIV: Still a very long way to go, but progress continues. PLoS Med. 2017 Nov; 14(11):e1002466.
Deeks SG, Lewin SR, Bekker LG. PMID: 29190733; PMCID: PMC5708775.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
-
Detection of HIV-1-specific gastrointestinal tissue resident CD8+ T-cells in chronic infection. Mucosal Immunol. 2018 05; 11(3):909-920.
Kiniry BE, Li S, Ganesh A, Hunt PW, Somsouk M, Skinner PJ, Deeks SG, Shacklett BL. PMID: 29139476; PMCID: PMC5953759.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansCells
-
Differential Inhibitory Receptor Expression on T Cells Delineates Functional Capacities in Chronic Viral Infection. J Virol. 2017 12 01; 91(23).
Teigler JE, Zelinskyy G, Eller MA, Bolton DL, Marovich M, Gordon AD, Alrubayyi A, Alter G, Robb ML, Martin JN, Deeks SG, Michael NL, Dittmer U, Streeck H. PMID: 28904197; PMCID: PMC5686724.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
-
HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study. PLoS Med. 2017 Nov; 14(11):e1002417.
Henrich TJ, Hatano H, Bacon O, Hogan LE, Rutishauser R, Hill A, Kearney MF, Anderson EM, Buchbinder SP, Cohen SE, Abdel-Mohsen M, Pohlmeyer CW, Fromentin R, Hoh R, Liu AY, McCune JM, Spindler J, Metcalf-Pate K, Hobbs KS, Thanh C, Gibson EA, Kuritzkes DR, Siliciano RF, Price RW, Richman DD, Chomont N, Siliciano JD, Mellors JW, Yukl SA, Blankson JN, Liegler T, Deeks SG. PMID: 29112956; PMCID: PMC5675377.
View in:
PubMed Mentions:
128 Fields:
Translation:
HumansCellsPHPublic Health
-
Association of HIV-1 Gag-Specific IgG Antibodies With Natural Control of HIV-1 Infection in Individuals Not Carrying HLA-B*57: 01 Is Only Observed in Viremic Controllers. J Acquir Immune Defic Syndr. 2017 11 01; 76(3):e90-e92.
Tjiam MC, Morshidi MA, Sariputra L, Martin JN, Deeks SG, Tan DBA, Lee S, Fernandez S, French MA. PMID: 28604502; PMCID: PMC5634911.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
-
An Optimized and Validated Method for Isolation and Characterization of Lymphocytes from HIV+ Human Gut Biopsies. AIDS Res Hum Retroviruses. 2017 Nov; 33(S1):S31-S39.
Trapecar M, Khan S, Roan NR, Chen TH, Telwatte S, Deswal M, Pao M, Somsouk M, Deeks SG, Hunt PW, Yukl S, Sanjabi S. PMID: 28882052; PMCID: PMC5684666.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
-
HLA-B*14:02-Restricted Env-Specific CD8+ T-Cell Activity Has Highly Potent Antiviral Efficacy Associated with Immune Control of HIV Infection. J Virol. 2017 11 15; 91(22).
Leitman EM, Willberg CB, Tsai MH, Chen H, Buus S, Chen F, Riddell L, Haas D, Fellay J, Goedert JJ, Piechocka-Trocha A, Walker BD, Martin J, Deeks S, Wolinsky SM, Martinson J, Martin M, Qi Y, Sáez-Cirión A, Yang OO, Matthews PC, Carrington M, Goulder PJR. PMID: 28878089; PMCID: PMC5660483.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCellsCTClinical Trials
-
Identification of Genetically Intact HIV-1 Proviruses in Specific CD4+ T Cells from Effectively Treated Participants. Cell Rep. 2017 Oct 17; 21(3):813-822.
Hiener B, Horsburgh BA, Eden JS, Barton K, Schlub TE, Lee E, von Stockenstrom S, Odevall L, Milush JM, Liegler T, Sinclair E, Hoh R, Boritz EA, Douek D, Fromentin R, Chomont N, Deeks SG, Hecht FM, Palmer S. PMID: 29045846; PMCID: PMC5960642.
View in:
PubMed Mentions:
230 Fields:
Translation:
HumansCells
-
Defining total-body AIDS-virus burden with implications for curative strategies. Nat Med. 2017 Nov; 23(11):1271-1276.
Estes JD, Kityo C, Ssali F, Swainson L, Makamdop KN, Del Prete GQ, Deeks SG, Luciw PA, Chipman JG, Beilman GJ, Hoskuldsson T, Khoruts A, Anderson J, Deleage C, Jasurda J, Schmidt TE, Hafertepe M, Callisto SP, Pearson H, Reimann T, Schuster J, Schoephoerster J, Southern P, Perkey K, Shang L, Wietgrefe SW, Fletcher CV, Lifson JD, Douek DC, McCune JM, Haase AT, Schacker TW. PMID: 28967921; PMCID: PMC5831193.
View in:
PubMed Mentions:
233 Fields:
Translation:
HumansCells
-
Anti-HERV-K (HML-2) capsid antibody responses in HIV elite controllers. Retrovirology. 2017 Aug 22; 14(1):41.
de Mulder M, SenGupta D, Deeks SG, Martin JN, Pilcher CD, Hecht FM, Sacha JB, Nixon DF, Michaud HA. PMID: 28830571; PMCID: PMC5568399.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
-
Terminal differentiation of T cells is strongly associated with CMV infection and increased in HIV-positive individuals on ART and lifestyle matched controls. PLoS One. 2017; 12(8):e0183357.
Booiman T, Wit FW, Girigorie AF, Maurer I, De Francesco D, Sabin CA, Harskamp AM, Prins M, Franceschi C, Deeks SG, Winston A, Reiss P, Kootstra NA, Co-morBidity in Relation to Aids (COBRA) Collaboration. PMID: 28806406; PMCID: PMC5555623.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCells
-
A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals. Pathog Immun. 2017; 2(3):310-334.
Cockerham LR, Yukl SA, Harvill K, Somsouk M, Joshi SK, Sinclair E, Liegler T, Hoh R, Lyons S, Hunt PW, Rupert A, Sereti I, Morcock DR, Rhodes A, Emson C, Hellerstein MK, Estes JD, Lewin S, Deeks SG, Hatano H. PMID: 28936485; PMCID: PMC5604865.
View in:
PubMed Mentions:
4
-
HIV Antibody Level as a Marker of HIV Persistence and Low-Level Viral Replication. J Infect Dis. 2017 07 01; 216(1):72-81.
Keating SM, Pilcher CD, Jain V, Lebedeva M, Hampton D, Abdel-Mohsen M, Deng X, Murphy G, Welte A, Facente SN, Hecht F, Deeks SG, Pillai SK, Busch MP. PMID: 28498985; PMCID: PMC5853429.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Utility of 2013 American College of Cardiology/American Heart Association Cholesterol Guidelines in HIV-Infected Adults With Carotid Atherosclerosis. Circ Cardiovasc Imaging. 2017 Jul; 10(7).
Phan BAP, Weigel B, Ma Y, Scherzer R, Li D, Hur S, Kalapus SC, Deeks S, Hsue P. PMID: 28674084; PMCID: PMC5516666.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansPHPublic Health
-
Preservation of Peripheral T Follicular Helper Cell Function in HIV Controllers. J Virol. 2017 07 15; 91(14).
Buranapraditkun S, Pissani F, Teigler JE, Schultz BT, Alter G, Marovich M, Robb ML, Eller MA, Martin J, Deeks S, Michael NL, Streeck H. PMID: 28468877; PMCID: PMC5487582.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
-
Ultrarapid Measurement of Diagnostic Antibodies by Magnetic Capture of Immune Complexes. Sci Rep. 2017 06 19; 7(1):3818.
Burbelo PD, Gunti S, Keller JM, Morse CG, Deeks SG, Lionakis MS, Kapoor A, Li Q, Cohen JI, Notkins AL, Alevizos I. PMID: 28630417; PMCID: PMC5476601.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
-
Signature of the Sleeper Cell: A Biomarker of HIV Latency Revealed. Trends Immunol. 2017 07; 38(7):457-458.
Pillai SK, Deeks SG. PMID: 28511815; PMCID: PMC6091624.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency. Cell Host Microbe. 2017 May 10; 21(5):569-579.e6.
Boehm D, Jeng M, Camus G, Gramatica A, Schwarzer R, Johnson JR, Hull PA, Montano M, Sakane N, Pagans S, Godin R, Deeks SG, Krogan NJ, Greene WC, Ott M. PMID: 28494238; PMCID: PMC5490666.
View in:
PubMed Mentions:
54 Fields:
Translation:
HumansCells
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High-throughput Characterization of HIV-1 Reservoir Reactivation Using a Single-Cell-in-Droplet PCR Assay. EBioMedicine. 2017 Jun; 20:217-229.
Yucha RW, Hobbs KS, Hanhauser E, Hogan LE, Nieves W, Ozen MO, Inci F, York V, Gibson EA, Thanh C, Shafiee H, El Assal R, Kiselinova M, Robles YP, Bae H, Leadabrand KS, Wang S, Deeks SG, Kuritzkes DR, Demirci U, Henrich TJ. PMID: 28529033; PMCID: PMC5478213.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansCells
-
Correction: Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial. PLoS Pathog. 2017 May; 13(5):e1006368.
Serrano-Villar S, Sainz T, Ma ZM, Utay NS, Wook-Chun T, Mann S, Kashuba AD, Siewe B, Albanese A, Troia-Cancio P, Sinclair E, Somasunderam A, Yotter T, Deeks SG, Landay A, Pollard RB, Miller CJ, Moreno S, Asmuth DM. PMID: 28467485; PMCID: PMC5415081.
View in:
PubMed Mentions: Fields:
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Early and Delayed Antiretroviral Therapy Results in Comparable Reductions in CD8+ T Cell Exhaustion Marker Expression. AIDS Res Hum Retroviruses. 2017 07; 33(7):658-667.
Rutishauser RL, Hartogensis W, Deguit CD, Krone M, Hoh R, Hecht FM, Pilcher CD, Bacchetti P, Deeks SG, Hunt PW, McCune JM. PMID: 28335609; PMCID: PMC5512309.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCellsPHPublic Health
-
T-bet+ B cells are induced by human viral infections and dominate the HIV gp140 response. JCI Insight. 2017 Apr 20; 2(8).
Knox JJ, Buggert M, Kardava L, Seaton KE, Eller MA, Canaday DH, Robb ML, Ostrowski MA, Deeks SG, Slifka MK, Tomaras GD, Moir S, Moody MA, Betts MR. PMID: 28422752; PMCID: PMC5396521.
View in:
PubMed Mentions:
99 Fields:
-
Correction: p16INK4a Expression and Immunologic Aging in Chronic HIV Infection. PLoS One. 2017; 12(4):e0176509.
Ribeiro SP, Milush JM, Cunha-Neto E, Kallas EG, Kalil J, Passero LFD, Hunt PW, Deeks SG, Nixon DF, SenGupta D. PMID: 28426830; PMCID: PMC5398691.
View in:
PubMed Mentions:
1 Fields:
-
A humanized mouse-based HIV-1 viral outgrowth assay with higher sensitivity than in vitro qVOA in detecting latently infected cells from individuals on ART with undetectable viral loads. Virology. 2017 07; 507:135-139.
Charlins P, Schmitt K, Remling-Mulder L, Hogan LE, Hanhauser E, Hobbs KS, Hecht F, Deeks SG, Henrich TJ, Akkina R. PMID: 28432928; PMCID: PMC5901664.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
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Comparison of dynamic monitoring strategies based on CD4 cell counts in virally suppressed, HIV-positive individuals on combination antiretroviral therapy in high-income countries: a prospective, observational study. Lancet HIV. 2017 06; 4(6):e251-e259.
Caniglia EC, Cain LE, Sabin CA, Robins JM, Logan R, Abgrall S, Mugavero MJ, Hernández-Díaz S, Meyer L, Seng R, Drozd DR, Seage GR, Bonnet F, Dabis F, Moore RD, Reiss P, van Sighem A, Mathews WC, Del Amo J, Moreno S, Deeks SG, Muga R, Boswell SL, Ferrer E, Eron JJ, Napravnik S, Jose S, Phillips A, Justice AC, Tate JP, Gill J, Pacheco A, Veloso VG, Bucher HC, Egger M, Furrer H, Porter K, Touloumi G, Crane H, Miro JM, Sterne JA, Costagliola D, Saag M, Hernán MA, HIV-CAUSAL Collaboration, Centers for AIDS Research Network of Integrated Clinical Systems. PMID: 28411091; PMCID: PMC5492888.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Human Immunodeficiency Virus Persistence and T-Cell Activation in Blood, Rectal, and Lymph Node Tissue in Human Immunodeficiency Virus-Infected Individuals Receiving Suppressive Antiretroviral Therapy. J Infect Dis. 2017 03 15; 215(6):911-919.
Khoury G, Fromentin R, Solomon A, Hartogensis W, Killian M, Hoh R, Somsouk M, Hunt PW, Girling V, Sinclair E, Bacchetti P, Anderson JL, Hecht FM, Deeks SG, Cameron PU, Chomont N, Lewin SR. PMID: 28453847; PMCID: PMC5407052.
View in:
PubMed Mentions:
56 Fields:
Translation:
HumansCells
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Measuring the Size of the Latent Human Immunodeficiency Virus Reservoir: The Present and Future of Evaluating Eradication Strategies. J Infect Dis. 2017 03 15; 215(suppl_3):S134-S141.
Henrich TJ, Deeks SG, Pillai SK. PMID: 28520968; PMCID: PMC5410981.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Cytokines Elevated in HIV Elite Controllers Reduce HIV Replication In Vitro and Modulate HIV Restriction Factor Expression. J Virol. 2017 03 15; 91(6).
Jacobs ES, Keating SM, Abdel-Mohsen M, Gibb SL, Heitman JW, Inglis HC, Martin JN, Zhang J, Kaidarova Z, Deng X, Wu S, Anastos K, Crystal H, Villacres MC, Young M, Greenblatt RM, Landay AL, Gange SJ, Deeks SG, Golub ET, Pillai SK, Norris PJ. PMID: 28053103; PMCID: PMC5331794.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells
-
Comparison of cross-sectional HIV incidence assay results from dried blood spots and plasma. PLoS One. 2017; 12(2):e0172283.
Schlusser KE, Pilcher C, Kallas EG, Santos BR, Deeks SG, Facente S, Keating SM, Busch MP, Murphy G, Welte A, Quinn T, Eshleman SH, Laeyendecker O. PMID: 28231277; PMCID: PMC5322916.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
-
Association of Arterial and Lymph Node Inflammation With Distinct Inflammatory Pathways in Human Immunodeficiency Virus Infection. JAMA Cardiol. 2017 02 01; 2(2):163-171.
Tawakol A, Ishai A, Li D, Takx RA, Hur S, Kaiser Y, Pampaloni M, Rupert A, Hsu D, Sereti I, Fromentin R, Chomont N, Ganz P, Deeks SG, Hsue PY. PMID: 27926762; PMCID: PMC5310978.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansCells
-
Mucosal Microbes Mitigate Maladies. Immunity. 2017 01 17; 46(1):1-3.
Vujkovic-Cvijin I, Deeks SG. PMID: 28099858.
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PubMed Mentions: Fields:
Translation:
Humans
-
Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals. Sci Rep. 2017 01 13; 7:40354.
Tauriainen J, Scharf L, Frederiksen J, Naji A, Ljunggren HG, Sönnerborg A, Lund O, Reyes-Terán G, Hecht FM, Deeks SG, Betts MR, Buggert M, Karlsson AC. PMID: 28084312; PMCID: PMC5233961.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansCells
-
Role of T-Cell Dysfunction, Inflammation, and Coagulation in Microvascular Disease in HIV. J Am Heart Assoc. 2016 12 20; 5(12).
Sinha A, Ma Y, Scherzer R, Hur S, Li D, Ganz P, Deeks SG, Hsue PY. PMID: 27998918; PMCID: PMC5210441.
View in:
PubMed Mentions:
36 Fields:
Translation:
HumansCells
-
The interferon paradox: can inhibiting an antiviral mechanism advance an HIV cure? J Clin Invest. 2017 01 03; 127(1):103-105.
Deeks SG, Odorizzi PM, Sekaly RP. PMID: 27941242; PMCID: PMC5199692.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Using observational data to emulate a randomized trial of dynamic treatment-switching strategies: an application to antiretroviral therapy. Int J Epidemiol. 2016 12 01; 45(6):2038-2049.
Cain LE, Saag MS, Petersen M, May MT, Ingle SM, Logan R, Robins JM, Abgrall S, Shepherd BE, Deeks SG, John Gill M, Touloumi G, Vourli G, Dabis F, Vandenhende MA, Reiss P, van Sighem A, Samji H, Hogg RS, Rybniker J, Sabin CA, Jose S, Del Amo J, Moreno S, Rodríguez B, Cozzi-Lepri A, Boswell SL, Stephan C, Pérez-Hoyos S, Jarrin I, Guest JL, D'Arminio Monforte A, Antinori A, Moore R, Campbell CN, Casabona J, Meyer L, Seng R, Phillips AN, Bucher HC, Egger M, Mugavero MJ, Haubrich R, Geng EH, Olson A, Eron JJ, Napravnik S, Kitahata MM, Van Rompaey SE, Teira R, Justice AC, Tate JP, Costagliola D, Sterne JA, Hernán MA, Antiretroviral Therapy Cohort Collaboration, the Centers for AIDS Research Network of Integrated Cli. PMID: 26721599; PMCID: PMC5841611.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansCells
-
Reverse geroscience: how does exposure to early diseases accelerate the age-related decline in health? Ann N Y Acad Sci. 2016 12; 1386(1):30-44.
Kohanski RA, Deeks SG, Gravekamp C, Halter JB, High K, Hurria A, Fuldner R, Green P, Huebner R, Macchiarini F, Sierra F. PMID: 27907230.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
p16INK4a Expression and Immunologic Aging in Chronic HIV Infection. PLoS One. 2016; 11(11):e0166759.
Ribeiro SP, Milush JM, Cunha-Neto E, Kallas EG, Kalil J, Passero LFD, Hunt PW, Deeks SG, Nixon DF, SenGupta D. PMID: 27861555; PMCID: PMC5115792.
View in:
PubMed Mentions:
10 Fields:
-
Predominance of weakly cytotoxic, T-betLowEomesNeg CD8+ T-cells in human gastrointestinal mucosa: implications for HIV infection. Mucosal Immunol. 2017 07; 10(4):1008-1020.
Kiniry BE, Ganesh A, Critchfield JW, Hunt PW, Hecht FM, Somsouk M, Deeks SG, Shacklett BL. PMID: 27827375; PMCID: PMC5423867.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCells
-
Psoriasis risk SNPs and their association with HIV-1 control. Hum Immunol. 2017 Feb; 78(2):179-184.
Nititham J, Gupta R, Zeng X, Hartogensis W, Nixon DF, Deeks SG, Hecht FM, Liao W. PMID: 27810495; PMCID: PMC5253078.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
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High-Sequence Diversity and Rapid Virus Turnover Contribute to Higher Rates of Coreceptor Switching in Treatment-Experienced Subjects with HIV-1 Viremia. AIDS Res Hum Retroviruses. 2017 03; 33(3):234-245.
Nedellec R, Herbeck JT, Hunt PW, Deeks SG, Mullins JI, Anton ED, Reeves JD, Mosier DE. PMID: 27604829; PMCID: PMC5333564.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Ongoing Clinical Trials of Human Immunodeficiency Virus Latency-Reversing and Immunomodulatory Agents. Open Forum Infect Dis. 2016 Oct; 3(4):ofw189.
Delagrèverie HM, Delaugerre C, Lewin SR, Deeks SG, Li JZ. PMID: 27757411; PMCID: PMC5066458.
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PubMed Mentions:
49
-
New insights into the heterogeneity of Th17 subsets contributing to HIV-1 persistence during antiretroviral therapy. Retrovirology. 2016 08 24; 13(1):59.
Wacleche VS, Goulet JP, Gosselin A, Monteiro P, Soudeyns H, Fromentin R, Jenabian MA, Vartanian S, Deeks SG, Chomont N, Routy JP, Ancuta P. PMID: 27553844; PMCID: PMC4995622.
View in:
PubMed Mentions:
58 Fields:
Translation:
HumansCells
-
Plasma IL-6 levels are independently associated with atherosclerosis and mortality in HIV-infected individuals on suppressive antiretroviral therapy. AIDS. 2016 08 24; 30(13):2065-74.
Hsu DC, Ma YF, Hur S, Li D, Rupert A, Scherzer R, Kalapus SC, Deeks S, Sereti I, Hsue PY. PMID: 27177313; PMCID: PMC5586221.
View in:
PubMed Mentions:
52 Fields:
Translation:
Humans
-
Defective proviruses rapidly accumulate during acute HIV-1 infection. Nat Med. 2016 09; 22(9):1043-9.
Bruner KM, Murray AJ, Pollack RA, Soliman MG, Laskey SB, Capoferri AA, Lai J, Strain MC, Lada SM, Hoh R, Ho YC, Richman DD, Deeks SG, Siliciano JD, Siliciano RF. PMID: 27500724; PMCID: PMC5014606.
View in:
PubMed Mentions:
443 Fields:
Translation:
HumansCells
-
HIV-1-Specific Antibody Response and Function after DNA Prime and Recombinant Adenovirus 5 Boost HIV Vaccine in HIV-Infected Subjects. PLoS One. 2016; 11(8):e0160341.
Gach JS, Gorlani A, Dotsey EY, Becerra JC, Anderson CT, Berzins B, Felgner PL, Forthal DN, Deeks SG, Wilkin TJ, Casazza JP, Koup RA, Katlama C, Autran B, Murphy RL, Achenbach CJ. PMID: 27500639; PMCID: PMC4976892.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCellsCTClinical Trials
-
The Benefits of Early Antiretroviral Therapy for HIV Infection: How Early is Early Enough? EBioMedicine. 2016 Sep; 11:7-8.
Lee SA, Deeks SG. PMID: 27515690; PMCID: PMC5049928.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
-
Anti-HIV Antibody Responses and the HIV Reservoir Size during Antiretroviral Therapy. PLoS One. 2016; 11(8):e0160192.
Lee SA, Bacchetti P, Chomont N, Fromentin R, Lewin SR, O'Doherty U, Palmer S, Richman DD, Siliciano JD, Yukl SA, Deeks SG, Burbelo PD. PMID: 27483366; PMCID: PMC4970722.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCells
-
Multiple Origins of Virus Persistence during Natural Control of HIV Infection. Cell. 2016 Aug 11; 166(4):1004-1015.
Boritz EA, Darko S, Swaszek L, Wolf G, Wells D, Wu X, Henry AR, Laboune F, Hu J, Ambrozak D, Hughes MS, Hoh R, Casazza JP, Vostal A, Bunis D, Nganou-Makamdop K, Lee JS, Migueles SA, Koup RA, Connors M, Moir S, Schacker T, Maldarelli F, Hughes SH, Deeks SG, Douek DC. PMID: 27453467; PMCID: PMC4983216.
View in:
PubMed Mentions:
116 Fields:
Translation:
HumansCells
-
CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART. PLoS Pathog. 2016 07; 12(7):e1005761.
Fromentin R, Bakeman W, Lawani MB, Khoury G, Hartogensis W, DaFonseca S, Killian M, Epling L, Hoh R, Sinclair E, Hecht FM, Bacchetti P, Deeks SG, Lewin SR, Sékaly RP, Chomont N. PMID: 27415008; PMCID: PMC4944956.
View in:
PubMed Mentions:
255 Fields:
Translation:
HumansCells
-
International AIDS Society global scientific strategy: towards an HIV cure 2016. Nat Med. 2016 08; 22(8):839-50.
Deeks SG, Lewin SR, Ross AL, Ananworanich J, Benkirane M, Cannon P, Chomont N, Douek D, Lifson JD, Lo YR, Kuritzkes D, Margolis D, Mellors J, Persaud D, Tucker JD, Barre-Sinoussi F, International AIDS Society Towards a Cure Working Group, Alter G, Auerbach J, Autran B, Barouch DH, Behrens G, Cavazzana M, Chen Z, Cohen ÉA, Corbelli GM, Eholié S, Eyal N, Fidler S, Garcia L, Grossman C, Henderson G, Henrich TJ, Jefferys R, Kiem HP, McCune J, Moodley K, Newman PA, Nijhuis M, Nsubuga MS, Ott M, Palmer S, Richman D, Saez-Cirion A, Sharp M, Siliciano J, Silvestri G, Singh J, Spire B, Taylor J, Tolstrup M, Valente S, van Lunzen J, Walensky R, Wilson I, Zack J. PMID: 27400264; PMCID: PMC5322797.
View in:
PubMed Mentions:
261 Fields:
Translation:
Humans
-
Persistent HIV-1 replication during antiretroviral therapy. Curr Opin HIV AIDS. 2016 07; 11(4):417-23.
Martinez-Picado J, Deeks SG. PMID: 27078619; PMCID: PMC4900428.
View in:
PubMed Mentions:
95 Fields:
Translation:
HumansCells
-
Persistence of integrated HIV DNA in CXCR3 + CCR6 + memory CD4+ T cells in HIV-infected individuals on antiretroviral therapy. AIDS. 2016 06 19; 30(10):1511-20.
Khoury G, Anderson JL, Fromentin R, Hartogenesis W, Smith MZ, Bacchetti P, Hecht FM, Chomont N, Cameron PU, Deeks SG, Lewin SR. PMID: 26807971; PMCID: PMC4889535.
View in:
PubMed Mentions:
50 Fields:
Translation:
HumansCells
-
Immunologic profiles distinguish aviremic HIV-infected adults. AIDS. 2016 06 19; 30(10):1553-62.
Ramirez CM, Sinclair E, Epling L, Lee SA, Jain V, Hsue PY, Hatano H, Conn D, Hecht FM, Martin JN, McCune JM, Deeks SG, Hunt PW. PMID: 26854811; PMCID: PMC5679214.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
-
Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation. PLoS Pathog. 2016 06; 12(6):e1005677.
Abdel-Mohsen M, Chavez L, Tandon R, Chew GM, Deng X, Danesh A, Keating S, Lanteri M, Samuels ML, Hoh R, Sacha JB, Norris PJ, Niki T, Shikuma CM, Hirashima M, Deeks SG, Ndhlovu LC, Pillai SK. PMID: 27253379; PMCID: PMC4890776.
View in:
PubMed Mentions:
43 Fields:
Translation:
HumansCells
-
Do Biomarkers of Inflammation, Monocyte Activation, and Altered Coagulation Explain Excess Mortality Between HIV Infected and Uninfected People? J Acquir Immune Defic Syndr. 2016 06 01; 72(2):206-213.
So-Armah KA, Tate JP, Chang CH, Butt AA, Gerschenson M, Gibert CL, Leaf D, Rimland D, Rodriguez-Barradas MC, Budoff MJ, Samet JH, Kuller LH, Deeks SG, Crothers K, Tracy RP, Crane HM, Sajadi MM, Tindle HA, Justice AC, Freiberg MS, VACS Project Team. PMID: 27824677; PMCID: PMC4867134.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansCells
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When to Monitor CD4 Cell Count and HIV RNA to Reduce Mortality and AIDS-Defining Illness in Virologically Suppressed HIV-Positive Persons on Antiretroviral Therapy in High-Income Countries: A Prospective Observational Study. J Acquir Immune Defic Syndr. 2016 Jun 01; 72(2):214-21.
Caniglia EC, Sabin C, Robins JM, Logan R, Cain LE, Abgrall S, Mugavero MJ, Hernandez-Diaz S, Meyer L, Seng R, Drozd DR, Seage GR, Bonnet F, Dabis F, Moore RR, Reiss P, van Sighem A, Mathews WC, Del Amo J, Moreno S, Deeks SG, Muga R, Boswell SL, Ferrer E, Eron JJ, Napravnik S, Jose S, Phillips A, Olson A, Justice AC, Tate JP, Bucher HC, Egger M, Touloumi G, Sterne JA, Costagliola D, Saag M, Hernán MA, Center for AIDS Research Network of Integrated Clinical Systems and the HIV-CAUSAL Collaboration. PMID: 26895294; PMCID: PMC4866894.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Relevance of Interleukin-6 and D-Dimer for Serious Non-AIDS Morbidity and Death among HIV-Positive Adults on Suppressive Antiretroviral Therapy. PLoS One. 2016; 11(5):e0155100.
Grund B, Baker JV, Deeks SG, Wolfson J, Wentworth D, Cozzi-Lepri A, Cohen CJ, Phillips A, Lundgren JD, Neaton JD, INSIGHT SMART/ESPRIT/SILCAAT Study Group. PMID: 27171281; PMCID: PMC4865234.
View in:
PubMed Mentions:
95 Fields:
Translation:
Humans
-
Immune Activation and HIV-Specific CD8(+) T Cells in Cerebrospinal Fluid of HIV Controllers and Noncontrollers. AIDS Res Hum Retroviruses. 2016 08; 32(8):791-800.
Ganesh A, Lemongello D, Lee E, Peterson J, McLaughlin BE, Ferre AL, Gillespie GM, Fuchs D, Deeks SG, Hunt PW, Price RW, Spudich SS, Shacklett BL. PMID: 27019338; PMCID: PMC4971411.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
-
HIV and Hepatitis C-Coinfected Patients Have Lower Low-Density Lipoprotein Cholesterol Despite Higher Proprotein Convertase Subtilisin Kexin 9 (PCSK9): An Apparent "PCSK9-Lipid Paradox". J Am Heart Assoc. 2016 04 29; 5(5).
Kohli P, Ganz P, Ma Y, Scherzer R, Hur S, Weigel B, Grunfeld C, Deeks S, Wasserman S, Scott R, Hsue PY. PMID: 27130349; PMCID: PMC4889164.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
T-Cell Activation Independently Associates With Immune Senescence in HIV-Infected Recipients of Long-term Antiretroviral Treatment. J Infect Dis. 2016 07 15; 214(2):216-25.
Cobos Jiménez V, Wit FW, Joerink M, Maurer I, Harskamp AM, Schouten J, Prins M, van Leeuwen EM, Booiman T, Deeks SG, Reiss P, Kootstra NA, AGEhIV Study Group. PMID: 27073222; PMCID: PMC8445638.
View in:
PubMed Mentions:
62 Fields:
Translation:
HumansCells
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Identifying Key Drivers of the Impact of an HIV Cure Intervention in Sub-Saharan Africa. J Infect Dis. 2016 07 01; 214(1):73-9.
Phillips AN, Cambiano V, Revill P, Nakagawa F, Lundgren JD, Bansi-Matharu L, Mabugu T, Sculpher M, Garnett G, Staprans S, Becker S, Murungu J, Lewin SR, Deeks SG, Hallett TB. PMID: 27034345; PMCID: PMC4907418.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Correction: Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial. PLoS Pathog. 2016 Mar; 12(3):e1005540.
Serrano-Villar S, Sainz T, Ma ZM, Utay NS, Chun TW, Mann S, Kashuba AD, Siewe B, Albanese A, Troia-Cancio P, Sinclair E, Somasunderam A, Yotter T, Deeks SG, Landay A, Pollard RB, Miller CJ, Moreno S, Asmuth DM. PMID: 27015639; PMCID: PMC4807777.
View in:
PubMed Mentions:
6 Fields:
-
Post-Treatment Controllers: Role in HIV "Cure" Research. Curr HIV/AIDS Rep. 2016 Feb; 13(1):1-9.
Cockerham LR, Hatano H, Deeks SG. PMID: 26781112.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
-
Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial. PLoS Pathog. 2016 Jan; 12(1):e1005381.
Serrano-Villar S, Sainz T, Ma ZM, Utay NS, Chun TW, Wook-Chun T, Mann S, Kashuba AD, Siewe B, Albanese A, Troia-Cancio P, Sinclair E, Somasunderam A, Yotter T, Deeks SG, Landay A, Pollard RB, Miller CJ, Moreno S, Asmuth DM. PMID: 26795282; PMCID: PMC4721954.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
-
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection. PLoS Pathog. 2016 Jan; 12(1):e1005349.
Chew GM, Fujita T, Webb GM, Burwitz BJ, Wu HL, Reed JS, Hammond KB, Clayton KL, Ishii N, Abdel-Mohsen M, Liegler T, Mitchell BI, Hecht FM, Ostrowski M, Shikuma CM, Hansen SG, Maurer M, Korman AJ, Deeks SG, Sacha JB, Ndhlovu LC. PMID: 26741490; PMCID: PMC4704737.
View in:
PubMed Mentions:
177 Fields:
Translation:
HumansAnimalsCells
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Cerebral vasoreactivity is impaired in treated, virally suppressed HIV-infected individuals. AIDS. 2016 Jan 02; 30(1):45-55.
Chow FC, Boscardin WJ, Mills C, Ko N, Carroll C, Price RW, Deeks S, Sorond FA, Hsue PY. PMID: 26372478; PMCID: PMC4703496.
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PubMed Mentions:
16 Fields:
Translation:
Humans
-
HIV reservoirs: what, where and how to target them. Nat Rev Microbiol. 2016 01; 14(1):55-60.
Churchill MJ, Deeks SG, Margolis DM, Siliciano RF, Swanstrom R. PMID: 26616417.
View in:
PubMed Mentions:
168 Fields:
Translation:
HumansCells
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Lack of Evidence for Molecular Mimicry in HIV-Infected Subjects. PLoS One. 2015; 10(11):e0127662.
Burbelo PD, Klimavicz JS, Deeks SG, Kovacs JA, Ragheb JA. PMID: 26599070; PMCID: PMC4657959.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Short-term administration of disulfiram for reversal of latent HIV infection: a phase 2 dose-escalation study. Lancet HIV. 2015 Dec; 2(12):e520-9.
Elliott JH, McMahon JH, Chang CC, Lee SA, Hartogensis W, Bumpus N, Savic R, Roney J, Hoh R, Solomon A, Piatak M, Gorelick RJ, Lifson J, Bacchetti P, Deeks SG, Lewin SR. PMID: 26614966; PMCID: PMC5108570.
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PubMed Mentions:
148 Fields:
Translation:
HumansCellsCTClinical Trials
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Virome analysis of antiretroviral-treated HIV patients shows no correlation between T-cell activation and anelloviruses levels. J Clin Virol. 2015 Nov; 72:106-13.
Li L, Deng X, Da Costa AC, Bruhn R, Deeks SG, Delwart E. PMID: 26479202; PMCID: PMC4697764.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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HIV infection. Nat Rev Dis Primers. 2015 10 01; 1:15035.
Deeks SG, Overbaugh J, Phillips A, Buchbinder S. PMID: 27188527.
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PubMed Mentions:
227 Fields:
Translation:
HumansCells
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The HIV Cure Research Agenda: The Role of Mathematical Modelling and Cost-Effectiveness Analysis. J Virus Erad. 2015; 1(4):245-249.
Freedberg KA, Possas C, Deeks S, Ross AL, Rosettie KL, Di Mascio M, Collins C, Walensky RP, Yazdanpanah Y. PMID: 26878073; PMCID: PMC4748959.
View in:
PubMed Mentions:
6
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Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor. Proc Natl Acad Sci U S A. 2015 Aug 25; 112(34):E4762-71.
Gornalusse GG, Mummidi S, Gaitan AA, Jimenez F, Ramsuran V, Picton A, Rogers K, Manoharan MS, Avadhanam N, Murthy KK, Martinez H, Molano Murillo A, Chykarenko ZA, Hutt R, Daskalakis D, Shostakovich-Koretskaya L, Abdool Karim S, Martin JN, Deeks SG, Hecht F, Sinclair E, Clark RA, Okulicz J, Valentine FT, Martinson N, Tiemessen CT, Ndung'u T, Hunt PW, He W, Ahuja SK. PMID: 26307764; PMCID: PMC4553789.
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PubMed Mentions:
32 Fields:
Translation:
HumansCells
-
Novel Biomarkers of Cardiac Stress, Cardiovascular Dysfunction, and Outcomes in HIV-Infected Individuals. JACC Heart Fail. 2015 Aug; 3(8):591-9.
Secemsky EA, Scherzer R, Nitta E, Wu AH, Lange DC, Deeks SG, Martin JN, Snider J, Ganz P, Hsue PY. PMID: 26164679; PMCID: PMC4529774.
View in:
PubMed Mentions:
46 Fields:
Translation:
Humans
-
Mitral Annular and Coronary Artery Calcification Are Associated with Mortality in HIV-Infected Individuals. PLoS One. 2015; 10(7):e0130592.
Lange DC, Glidden D, Secemsky EA, Ordovas K, Deeks SG, Martin JN, Bolger AF, Hsue PY. PMID: 26132465; PMCID: PMC4488486.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals. EBioMedicine. 2015 Aug; 2(8):874-83.
Procopio FA, Fromentin R, Kulpa DA, Brehm JH, Bebin AG, Strain MC, Richman DD, O'Doherty U, Palmer S, Hecht FM, Hoh R, Barnard RJ, Miller MD, Hazuda DJ, Deeks SG, Sékaly RP, Chomont N. PMID: 26425694; PMCID: PMC4563128.
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PubMed Mentions:
175 Fields:
Translation:
HumansCells
-
View in:
PubMed Mentions:
101 Fields:
Translation:
Humans
-
Viremic control and viral coreceptor usage in two HIV-1-infected persons homozygous for CCR5 Δ32. AIDS. 2015 May 15; 29(8):867-76.
Henrich TJ, Hanhauser E, Hu Z, Stellbrink HJ, Noah C, Martin JN, Deeks SG, Kuritzkes DR, Pereyra F. PMID: 25730507; PMCID: PMC4473772.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
-
Viremic HIV Controllers Exhibit High Plasmacytoid Dendritic Cell-Reactive Opsonophagocytic IgG Antibody Responses against HIV-1 p24 Associated with Greater Antibody Isotype Diversification. J Immunol. 2015 Jun 01; 194(11):5320-8.
Tjiam MC, Taylor JP, Morshidi MA, Sariputra L, Burrows S, Martin JN, Deeks SG, Tan DB, Lee S, Fernandez S, French MA. PMID: 25911748; PMCID: PMC4492937.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
-
Summary of the National Advisory Committee on Immunization's Update on the recommended human papillomavirus (HPV) vaccine immunization schedule. Can Commun Dis Rep. 2015 Apr 20; 41(Suppl 3):11-13.
Ismail S, Deeks S, National Advisory Committee on Immunization. PMID: 29769961; PMCID: PMC5868570.
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PubMed Mentions:
14 Fields:
-
Clinical and demographic factors associated with low viral load in early untreated HIV infection in the INSIGHT Strategic Timing of AntiRetroviral Treatment (START) trial. HIV Med. 2015 Apr; 16 Suppl 1:37-45.
Law MG, Achhra A, Deeks SG, Gazzard B, Migueles SA, Novak RM, Ristola M, International Network for Strategic Initiatives in Global HIV Trials (INSIGHT) START Study Group. PMID: 25711322; PMCID: PMC4341944.
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PubMed Mentions:
4 Fields:
Translation:
Humans
-
HIV eradication symposium: will the brain be left behind? J Neurovirol. 2015 Jun; 21(3):322-34.
Brew BJ, Robertson K, Wright EJ, Churchill M, Crowe SM, Cysique LA, Deeks S, Garcia JV, Gelman B, Gray LR, Johnson T, Joseph J, Margolis DM, Mankowski JL, Spencer B. PMID: 25750070; PMCID: PMC4432099.
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PubMed Mentions:
11 Fields:
Translation:
Humans
-
Longitudinal Genetic Characterization Reveals That Cell Proliferation Maintains a Persistent HIV Type 1 DNA Pool During Effective HIV Therapy. J Infect Dis. 2015 Aug 15; 212(4):596-607.
von Stockenstrom S, Odevall L, Lee E, Sinclair E, Bacchetti P, Killian M, Epling L, Shao W, Hoh R, Ho T, Faria NR, Lemey P, Albert J, Hunt P, Loeb L, Pilcher C, Poole L, Hatano H, Somsouk M, Douek D, Boritz E, Deeks SG, Hecht FM, Palmer S. PMID: 25712966; PMCID: PMC4539896.
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PubMed Mentions:
99 Fields:
Translation:
HumansCells
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Select host restriction factors are associated with HIV persistence during antiretroviral therapy. AIDS. 2015 Feb 20; 29(4):411-20.
Abdel-Mohsen M, Wang C, Strain MC, Lada SM, Deng X, Cockerham LR, Pilcher CD, Hecht FM, Liegler T, Richman DD, Deeks SG, Pillai SK. PMID: 25602681; PMCID: PMC4385712.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Effect of therapeutic intensification followed by HIV DNA prime and rAd5 boost vaccination on HIV-specific immunity and HIV reservoir (EraMune 02): a multicentre randomised clinical trial. Lancet HIV. 2015 Mar; 2(3):e82-91.
Achenbach CJ, Assoumou L, Deeks SG, Wilkin TJ, Berzins B, Casazza JP, Lambert-Niclot S, Koup RA, Costagliola D, Calvez V, Katlama C, Autran B, Murphy RL, EraMune 02 study team. PMID: 26424549; PMCID: PMC6322849.
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CD4/CD8 ratio: an emerging biomarker for HIV. Lancet HIV. 2015 Mar; 2(3):e76-7.
Serrano-Villar S, Deeks SG. PMID: 26424546.
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PubMed Mentions:
24 Fields:
Translation:
Humans
-
CD41 T cell recovery during suppression of HIV replication: an international comparison of the immunological efficacy of antiretroviral therapy in North America, Asia and Africa. Int J Epidemiol. 2015 Feb; 44(1):251-63.
Geng EH, Neilands TB, Thièbaut R, Bwana MB, Nash D, Moore RD, Wood R, Zannou DM, Althoff KN, Lim PL, Nachega JB, Easterbrook PJ, Kambugu A, Little F, Nakigozi G, Nakanjako D, Kiggundu V, Ki Li PC, Bangsberg DR, Fox MP, Prozesky H, Hunt PW, Davies MA, Reynolds SJ, Egger M, Yiannoutsos CT, Vittinghoff EV, Deeks SG, Martin JN. PMID: 25859596; PMCID: PMC4339766.
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PubMed Mentions:
10 Fields:
Translation:
Humans
-
Soluble T cell immunoglobulin mucin domain 3 is shed from CD8+ T cells by the sheddase ADAM10, is increased in plasma during untreated HIV infection, and correlates with HIV disease progression. J Virol. 2015 Apr; 89(7):3723-36.
Clayton KL, Douglas-Vail MB, Nur-ur Rahman AK, Medcalf KE, Xie IY, Chew GM, Tandon R, Lanteri MC, Norris PJ, Deeks SG, Ndhlovu LC, Ostrowski MA. PMID: 25609823; PMCID: PMC4403393.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansCells
-
CD8+ T-cells count in acute myocardial infarction in HIV disease in a predominantly male cohort. Biomed Res Int. 2015; 2015:246870.
Badejo OA, Chang CC, So-Armah KA, Tracy RP, Baker JV, Rimland D, Butt AA, Gordon AJ, Rinaldo CR, Kraemer K, Samet JH, Tindle HA, Goetz MB, Rodriguez-Barradas MC, Bedimo R, Gibert CL, Leaf DA, Kuller LH, Deeks SG, Justice AC, Freiberg MS. PMID: 25688354; PMCID: PMC4320893.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
-
Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations. Nature. 2015 Jan 15; 517(7534):381-5.
Deng K, Pertea M, Rongvaux A, Wang L, Durand CM, Ghiaur G, Lai J, McHugh HL, Hao H, Zhang H, Margolick JB, Gurer C, Murphy AJ, Valenzuela DM, Yancopoulos GD, Deeks SG, Strowig T, Kumar P, Siliciano JD, Salzberg SL, Flavell RA, Shan L, Siliciano RF. PMID: 25561180; PMCID: PMC4406054.
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PubMed Mentions:
323 Fields:
Translation:
HumansAnimalsCells
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Gut epithelial barrier and systemic inflammation during chronic HIV infection. AIDS. 2015 Jan 02; 29(1):43-51.
Somsouk M, Estes JD, Deleage C, Dunham RM, Albright R, Inadomi JM, Martin JN, Deeks SG, McCune JM, Hunt PW. PMID: 25387317; PMCID: PMC4444362.
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PubMed Mentions:
111 Fields:
Translation:
HumansCells
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The immunologic effects of mesalamine in treated HIV-infected individuals with incomplete CD4+ T cell recovery: a randomized crossover trial. PLoS One. 2014; 9(12):e116306.
Somsouk M, Dunham RM, Cohen M, Albright R, Abdel-Mohsen M, Liegler T, Lifson J, Piatak M, Gorelick R, Huang Y, Wu Y, Hsue PY, Martin JN, Deeks SG, McCune JM, Hunt PW. PMID: 25545673; PMCID: PMC4283685.
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PubMed Mentions:
38 Fields:
Translation:
HumansCells
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High Transmissibility During Early HIV Infection Among Men Who Have Sex With Men-San Francisco, California. J Infect Dis. 2015 Jun 01; 211(11):1757-60.
Hollingsworth TD, Pilcher CD, Hecht FM, Deeks SG, Fraser C. PMID: 25542958; PMCID: PMC4425938.
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PubMed Mentions:
17 Fields:
Translation:
Humans
-
Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy. PLoS Pathog. 2014 Oct; 10(10):e1004473.
Elliott JH, Wightman F, Solomon A, Ghneim K, Ahlers J, Cameron MJ, Smith MZ, Spelman T, McMahon J, Velayudham P, Brown G, Roney J, Watson J, Prince MH, Hoy JF, Chomont N, Fromentin R, Procopio FA, Zeidan J, Palmer S, Odevall L, Johnstone RW, Martin BP, Sinclair E, Deeks SG, Hazuda DJ, Cameron PU, Sékaly RP, Lewin SR. PMID: 25393648; PMCID: PMC4231123.
View in:
PubMed Mentions:
332 Fields:
Translation:
HumansCellsCTClinical Trials
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Towards an HIV cure. J Int AIDS Soc. 2014; 17(4 Suppl 3):19479.
Deeks S. PMID: 25393988; PMCID: PMC4224933.
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PubMed Mentions:
6 Fields:
-
Lymphoid fibrosis occurs in long-term nonprogressors and persists with antiretroviral therapy but may be reversible with curative interventions. J Infect Dis. 2015 Apr 01; 211(7):1068-75.
Sanchez JL, Hunt PW, Reilly CS, Hatano H, Beilman GJ, Khoruts A, Jasurda JS, Somsouk M, Thorkelson A, Russ S, Anderson J, Deeks SG, Schacker TW. PMID: 25344521; PMCID: PMC4416122.
View in:
PubMed Mentions:
39 Fields:
Translation:
HumansCells
-
HIV Prevention and Treatment Fields Join Forces. EBioMedicine. 2014 Nov; 1(1):4-5.
Deeks SG, Siliciano R. PMID: 26137503; PMCID: PMC4457402.
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PubMed Mentions:
1 Fields:
-
CD4+ and CD8+ T cell activation are associated with HIV DNA in resting CD4+ T cells. PLoS One. 2014; 9(10):e110731.
Cockerham LR, Siliciano JD, Sinclair E, O'Doherty U, Palmer S, Yukl SA, Strain MC, Chomont N, Hecht FM, Siliciano RF, Richman DD, Deeks SG. PMID: 25340755; PMCID: PMC4207702.
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PubMed Mentions:
69 Fields:
Translation:
HumansCells
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Biomarker reveals HIV's hidden reservoir. Elife. 2014 Oct 16; 3:e04742.
Cockerham LR, Deeks SG. PMID: 25321627; PMCID: PMC4199414.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
The CD8⁺ memory stem T cell (T(SCM)) subset is associated with improved prognosis in chronic HIV-1 infection. J Virol. 2014 Dec; 88(23):13836-44.
Ribeiro SP, Milush JM, Cunha-Neto E, Kallas EG, Kalil J, Somsouk M, Hunt PW, Deeks SG, Nixon DF, SenGupta D. PMID: 25253339; PMCID: PMC4248986.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansCells
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Delayed switch of antiretroviral therapy after virologic failure associated with elevated mortality among HIV-infected adults in Africa. AIDS. 2014 Sep 10; 28(14):2097-107.
Petersen ML, Tran L, Geng EH, Reynolds SJ, Kambugu A, Wood R, Bangsberg DR, Yiannoutsos CT, Deeks SG, Martin JN. PMID: 24977440; PMCID: PMC4317283.
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PubMed Mentions:
70 Fields:
Translation:
HumansCells
-
Limited HIV infection of central memory and stem cell memory CD4+ T cells is associated with lack of progression in viremic individuals. PLoS Pathog. 2014 Aug; 10(8):e1004345.
Klatt NR, Bosinger SE, Peck M, Richert-Spuhler LE, Heigele A, Gile JP, Patel N, Taaffe J, Julg B, Camerini D, Torti C, Martin JN, Deeks SG, Sinclair E, Hecht FM, Lederman MM, Paiardini M, Kirchhoff F, Brenchley JM, Hunt PW, Silvestri G. PMID: 25167059; PMCID: PMC4148445.
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PubMed Mentions:
55 Fields:
Translation:
HumansCells
-
Levels of circulating myeloid subpopulations and of heme oxygenase-1 do not predict CD4(+) T cell recovery after the initiation of antiretroviral therapy for HIV disease. AIDS Res Ther. 2014; 11:27.
Seu L, Ortiz GM, Burt TD, Deeks SG, Martin JN, McCune JM. PMID: 25180041; PMCID: PMC4150425.
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PubMed Mentions:
2 Fields:
-
Markers of inflammation and activation of coagulation are associated with anaemia in antiretroviral-treated HIV disease. AIDS. 2014 Jul 31; 28(12):1791-6.
Borges ÁH, Weitz JI, Collins G, Baker JV, Lévy Y, Davey RT, Phillips AN, Neaton JD, Lundgren JD, Deeks SG, INSIGHT SILCAAT Scientific Committee. PMID: 25003720; PMCID: PMC4499102.
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PubMed Mentions:
17 Fields:
Translation:
Humans
-
Programmed death-1 expression on CD4⁺ and CD8⁺ T cells in treated and untreated HIV disease. AIDS. 2014 Jul 31; 28(12):1749-58.
Cockerham LR, Jain V, Sinclair E, Glidden DV, Hartogenesis W, Hatano H, Hunt PW, Martin JN, Pilcher CD, Sekaly R, McCune JM, Hecht FM, Deeks SG. PMID: 24871455; PMCID: PMC4206412.
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PubMed Mentions:
69 Fields:
Translation:
HumansCells
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Towards a cure for HIV--are we making progress? Lancet. 2014 Jul 19; 384(9939):209-11.
Lewin SR, Deeks SG, Barré-Sinoussi F. PMID: 25042220.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Antiretroviral therapy: stubborn limitations persist. Lancet. 2014 Jul 19; 384(9939):214-6.
Deeks SG, Hunt PW. PMID: 25042221.
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PubMed Mentions: Fields:
Translation:
Humans
-
Cutting edge: An antibody recognizing ancestral endogenous virus glycoproteins mediates antibody-dependent cellular cytotoxicity on HIV-1-infected cells. J Immunol. 2014 Aug 15; 193(4):1544-8.
Michaud HA, SenGupta D, de Mulder M, Deeks SG, Martin JN, Kobie JJ, Sacha JB, Nixon DF. PMID: 25024383; PMCID: PMC4120895.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Immunologic strategies for HIV-1 remission and eradication. Science. 2014 Jul 11; 345(6193):169-74.
Barouch DH, Deeks SG. PMID: 25013067; PMCID: PMC4096716.
View in:
PubMed Mentions:
124 Fields:
Translation:
HumansCellsPHPublic Health
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Exogenous and endogenous hyaluronic acid reduces HIV infection of CD4(+) T cells. Immunol Cell Biol. 2014 Oct; 92(9):770-80.
Li P, Fujimoto K, Bourguingnon L, Yukl S, Deeks S, Wong JK. PMID: 24957217; PMCID: PMC4205896.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
Decreased HIV type 1 transcription in CCR5-Δ32 heterozygotes during suppressive antiretroviral therapy. J Infect Dis. 2014 Dec 01; 210(11):1838-43.
Wang C, Abdel-Mohsen M, Strain MC, Lada SM, Yukl S, Cockerham LR, Pilcher CD, Hecht FM, Sinclair E, Liegler T, Richman DD, Deeks SG, Pillai SK. PMID: 24935955; PMCID: PMC4271057.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
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PubMed Mentions:
21 Fields:
Translation:
Humans
-
Galectin-9 is rapidly released during acute HIV-1 infection and remains sustained at high levels despite viral suppression even in elite controllers. AIDS Res Hum Retroviruses. 2014 Jul; 30(7):654-64.
Tandon R, Chew GM, Byron MM, Borrow P, Niki T, Hirashima M, Barbour JD, Norris PJ, Lanteri MC, Martin JN, Deeks SG, Ndhlovu LC. PMID: 24786365; PMCID: PMC4077009.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansCells
-
Sevelamer does not decrease lipopolysaccharide or soluble CD14 levels but decreases soluble tissue factor, low-density lipoprotein (LDL) cholesterol, and oxidized LDL cholesterol levels in individuals with untreated HIV infection. J Infect Dis. 2014 Nov 15; 210(10):1549-54.
Sandler NG, Zhang X, Bosch RJ, Funderburg NT, Choi AI, Robinson JK, Fine DM, Coombs RW, Jacobson JM, Landay AL, Douek DC, Tressler R, Read SW, Wilson CC, Deeks SG, Lederman MM, Gandhi RT, AIDS Clinical Trials Group A5296 Team. PMID: 24864123; PMCID: PMC4215074.
View in:
PubMed Mentions:
46 Fields:
Translation:
HumansCTClinical Trials
-
HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality. PLoS Pathog. 2014 May; 10(5):e1004078.
Serrano-Villar S, Sainz T, Lee SA, Hunt PW, Sinclair E, Shacklett BL, Ferre AL, Hayes TL, Somsouk M, Hsue PY, Van Natta ML, Meinert CL, Lederman MM, Hatano H, Jain V, Huang Y, Hecht FM, Martin JN, McCune JM, Moreno S, Deeks SG. PMID: 24831517; PMCID: PMC4022662.
View in:
PubMed Mentions:
311 Fields:
Translation:
HumansCells
-
A closer look at hepatitis C clearance in HIV controllers: a response. AIDS. 2014 May 15; 28(8):1241-2.
Asher AK, Santos GM, Evans J, Dokubo EK, Lee TH, Martin JN, Deeks SG, Tobler LH, Busch M, Hunt PW, Page K. PMID: 25028914; PMCID: PMC4214212.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Soluble markers of inflammation and coagulation but not T-cell activation predict non-AIDS-defining morbid events during suppressive antiretroviral treatment. J Infect Dis. 2014 Oct 15; 210(8):1248-59.
Tenorio AR, Zheng Y, Bosch RJ, Krishnan S, Rodriguez B, Hunt PW, Plants J, Seth A, Wilson CC, Deeks SG, Lederman MM, Landay AL. PMID: 24795473; PMCID: PMC4192039.
View in:
PubMed Mentions:
307 Fields:
Translation:
HumansCells
-
Dependence on the CCR5 coreceptor for viral replication explains the lack of rebound of CXCR4-predicted HIV variants in the Berlin patient. Clin Infect Dis. 2014 Aug 15; 59(4):596-600.
Symons J, Vandekerckhove L, Hütter G, Wensing AM, van Ham PM, Deeks SG, Nijhuis M. PMID: 24759824; PMCID: PMC4990826.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Lymphoma immune reconstitution inflammatory syndrome in the center for AIDS research network of integrated clinical systems cohort. Clin Infect Dis. 2014 Jul 15; 59(2):279-86.
Gopal S, Patel MR, Achenbach CJ, Yanik EL, Cole SR, Napravnik S, Burkholder GA, Mathews WC, Rodriguez B, Deeks SG, Mayer KH, Moore RD, Kitahata MM, Richards KL, Eron JJ. PMID: 24755860; PMCID: PMC4102912.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
-
Gut epithelial barrier dysfunction and innate immune activation predict mortality in treated HIV infection. J Infect Dis. 2014 Oct 15; 210(8):1228-38.
Hunt PW, Sinclair E, Rodriguez B, Shive C, Clagett B, Funderburg N, Robinson J, Huang Y, Epling L, Martin JN, Deeks SG, Meinert CL, Van Natta ML, Jabs DA, Lederman MM. PMID: 24755434; PMCID: PMC4192038.
View in:
PubMed Mentions:
294 Fields:
Translation:
HumansCells
-
Regulatory B cells inhibit cytotoxic T lymphocyte (CTL) activity and elimination of infected CD4 T cells after in vitro reactivation of HIV latent reservoirs. PLoS One. 2014; 9(4):e92934.
Siewe B, Wallace J, Rygielski S, Stapleton JT, Martin J, Deeks SG, Landay A. PMID: 24739950; PMCID: PMC3989168.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
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Reduction of HIV persistence following transplantation in HIV-infected kidney transplant recipients. Am J Transplant. 2014 May; 14(5):1136-41.
Stock PG, Barin B, Hatano H, Rogers RL, Roland ME, Lee TH, Busch M, Deeks SG, for Solid Organ Transplantation in HIV Study Investigators. PMID: 24698537; PMCID: PMC4012326.
View in:
PubMed Mentions:
36 Fields:
Translation:
HumansCells
-
LILRB2 interaction with HLA class I correlates with control of HIV-1 infection. PLoS Genet. 2014 Mar; 10(3):e1004196.
Bashirova AA, Martin-Gayo E, Jones DC, Qi Y, Apps R, Gao X, Burke PS, Taylor CJ, Rogich J, Wolinsky S, Bream JH, Duggal P, Hussain S, Martinson J, Weintrob A, Kirk GD, Fellay J, Buchbinder SP, Goedert JJ, Deeks SG, Pereyra F, Trowsdale J, Lichterfeld M, Telenti A, Walker BD, Allen RL, Carrington M, Yu XG. PMID: 24603468; PMCID: PMC3945438.
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54 Fields:
Translation:
HumansCells
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The kynurenine pathway of tryptophan catabolism, CD4+ T-cell recovery, and mortality among HIV-infected Ugandans initiating antiretroviral therapy. J Infect Dis. 2014 Aug 01; 210(3):383-91.
Byakwaga H, Boum Y, Huang Y, Muzoora C, Kembabazi A, Weiser SD, Bennett J, Cao H, Haberer JE, Deeks SG, Bangsberg DR, McCune JM, Martin JN, Hunt PW. PMID: 24585899; PMCID: PMC4148610.
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77 Fields:
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HumansCells
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Low proportions of CD28- CD8+ T cells expressing CD57 can be reversed by early ART initiation and predict mortality in treated HIV infection. J Infect Dis. 2014 Aug 01; 210(3):374-82.
Lee SA, Sinclair E, Jain V, Huang Y, Epling L, Van Natta M, Meinert CL, Martin JN, McCune JM, Deeks SG, Lederman MM, Hecht FM, Hunt PW. PMID: 24585893; PMCID: PMC4110459.
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PubMed Mentions:
38 Fields:
Translation:
HumansCells
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Impact of HIV on CD8+ T cell CD57 expression is distinct from that of CMV and aging. PLoS One. 2014; 9(2):e89444.
Lee SA, Sinclair E, Hatano H, Hsue PY, Epling L, Hecht FM, Bangsberg DR, Martin JN, McCune JM, Deeks SG, Hunt PW. PMID: 24586783; PMCID: PMC3937334.
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PubMed Mentions:
55 Fields:
Translation:
HumansCells
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Increased levels of asymmetric dimethylarginine are associated with pulmonary arterial hypertension in HIV infection. AIDS. 2014 Feb 20; 28(4):511-9.
Parikh RV, Scherzer R, Nitta EM, Leone A, Hur S, Mistry V, Macgregor JS, Martin JN, Deeks SG, Ganz P, Hsue PY. PMID: 24469026; PMCID: PMC4149286.
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25 Fields:
Translation:
Humans
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Differential escape patterns within the dominant HLA-B*57:03-restricted HIV Gag epitope reflect distinct clade-specific functional constraints. J Virol. 2014 May; 88(9):4668-78.
Payne RP, Branch S, Kløverpris H, Matthews PC, Koofhethile CK, Strong T, Adland E, Leitman E, Frater J, Ndung'u T, Hunter E, Haubrich R, Mothe B, Edwards A, Riddell L, Chen F, Harrigan PR, Brumme ZL, Mallal S, John M, Jooste JP, Shapiro R, Deeks SG, Walker BD, Brander C, Landis C, Carlson JM, Prado JG, Goulder PJ. PMID: 24501417; PMCID: PMC3993828.
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14 Fields:
Translation:
HumansCells
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Discordance between peripheral and colonic markers of inflammation during suppressive ART. J Acquir Immune Defic Syndr. 2014 Feb 01; 65(2):133-41.
Dunham RM, Vujkovic-Cvijin I, Yukl SA, Broadhurst MJ, Loke P, Albright RG, Wong JK, Lederman MM, Somsouk M, Hunt PW, Martin JN, Deeks SG, McCune JM. PMID: 24121758; PMCID: PMC3997573.
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20 Fields:
Translation:
Humans
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Trans-activation, post-transcriptional maturation, and induction of antibodies to HERV-K (HML-2) envelope transmembrane protein in HIV-1 infection. Retrovirology. 2014 Jan 28; 11:10.
Michaud HA, de Mulder M, SenGupta D, Deeks SG, Martin JN, Pilcher CD, Hecht FM, Sacha JB, Nixon DF. PMID: 24472118; PMCID: PMC3907665.
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28 Fields:
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HumansCells
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A comparison of methods for measuring rectal HIV levels suggests that HIV DNA resides in cells other than CD4+ T cells, including myeloid cells. AIDS. 2014 Jan 28; 28(3):439-42.
Yukl SA, Sinclair E, Somsouk M, Hunt PW, Epling L, Killian M, Girling V, Li P, Havlir DV, Deeks SG, Wong JK, Hatano H. PMID: 24322272; PMCID: PMC4130176.
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PubMed Mentions:
42 Fields:
Translation:
HumansCells
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Targeting host nucleotide biosynthesis with resveratrol inhibits emtricitabine-resistant HIV-1. AIDS. 2014 Jan 28; 28(3):317-23.
Heredia A, Davis C, Amin MN, Le NM, Wainberg MA, Oliveira M, Deeks SG, Wang LX, Redfield RR. PMID: 24326355; PMCID: PMC4469130.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Composition and function of T cell subpopulations are slow to change despite effective antiretroviral treatment of HIV disease. PLoS One. 2014; 9(1):e85613.
Emu B, Moretto WJ, Hoh R, Krone M, Martin JN, Nixon DF, Deeks SG, McCune JM. PMID: 24465619; PMCID: PMC3897457.
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24