Zena Werb, PhD

Title(s)Professor, Anatomy
SchoolSchool of Medicine
AddressLocation Required
Varies CA 00000
Phone415-476-4564
ORCID ORCID Icon0000-0002-6525-3872 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of Toronto (University College), , Toronto, CanadaHonors B.Sc.06/1966Biochemistry
    Rockefeller University, New York, NYPh.D.1971Cell Biology
    Strangeways Research Laboratory, Cambridge, UKPost-doc.08/1973Protein Chemistry
    Collapse Awards and Honors
    American Association for Cancer research2018Distinguished Lectureship in Breast Cancer Research Award
    Academy of the American Association for Cancer Research2019Fellow

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Integrative approach to heterogeneity in breast cancer metastasis
    NIH U01CA199315Jun 1, 2016 - May 31, 2021
    Role: Principal Investigator
    Role of GATA3 in transcriptional pathways suppressing breast cancer metastasis
    NIH R01CA190851Jul 1, 2015 - Jun 30, 2020
    Role: Principal Investigator
    (PQC4) Fate of cells disseminating from human breast cancer xenografts
    NIH R01CA180039Aug 1, 2013 - Jun 30, 2017
    Role: Principal Investigator
    Environmental Effect on the Mammary Gland across the Lifespan
    NIH U01ES019458Sep 1, 2010 - Jul 31, 2015
    Role: Principal Investigator
    Caliper Life Sciences Xenogen IVIS Imager
    NIH S10RR026435Feb 18, 2010 - Feb 17, 2011
    Role: Principal Investigator
    TRANSCRIPTIONAL REGULATION OF BREAST CANCER METASTASIS
    NIH R01CA129523Jul 1, 2008 - Apr 30, 2014
    Role: Principal Investigator
    Matrix Metalloproteinases Gordon Conference
    NIH R13CA115182Jun 1, 2005 - May 31, 2010
    Role: Co-Principal Investigator
    Molecular and Cellular Mechanisms in Cancer
    NIH T32CA108462Sep 1, 2004 - Aug 31, 2025
    Role: Principal Investigator
    Resource for X-ray Tomography of Whole Cells
    NIH P41RR019664May 6, 2004 - Apr 30, 2013
    Role: Co-Investigator
    Perkin Elmer Ultraview Spinning Disc Confocal Microscope
    NIH S10RR019401Apr 1, 2004 - Mar 31, 2006
    Role: Principal Investigator
    Smoke-induced AP-1 controls mucous vs squamous phenotype
    NIH R01HL075602Jan 20, 2004 - Dec 31, 2008
    Role: Principal Investigator
    Matrix Metalloproteases Regulate Mesenchymal Stem Cells
    NIH R01AG023218Jul 1, 2003 - Jun 30, 2007
    Role: Principal Investigator
    Gordon Research Conference on Matrix Metalloproteinases
    NIH R13DE015313Jun 1, 2003 - May 31, 2004
    Role: Principal Investigator
    Role of Chloride Channels in Mucin Production
    NIH R01HL073309Apr 1, 2003 - Mar 31, 2007
    Role: Principal Investigator
    Mucosal Immune Barrier in Infection and Immunity
    NIH P01AI053194Sep 30, 2002 - Aug 31, 2014
    Role: Co-Investigator
    Extracellular remodeling in bone development and repair
    NIH R01AR046238Sep 1, 1999 - Jan 31, 2011
    Role: Principal Investigator
    CELLULAR AND MOLECULAR RESPONSES TO LOW DOSE RADIATION
    NIH R01CA075072Aug 15, 1997 - Nov 30, 2002
    Role: Principal Investigator
    Proteases in Cancer Biology and Drug Development
    NIH P01CA072006Jun 10, 1997 - Jun 30, 2010
    Role: Principal Investigator
    Role of Metalloproteinases in Mammary Gland Remodeling
    NIH R01CA057621Apr 15, 1993 - Aug 31, 2019
    Role: Principal Investigator
    ADHESION AND REMODELING MECHANISMS IN GINGIVA AND BONE
    NIH P50DE010306Dec 1, 1992 - Oct 31, 1999
    Role: Co-Investigator
    DEVELOPMENTAL BIOLOGY OF THE IMPLANTING MAMMALIAN EMBRYO
    NIH P01HD026732Feb 1, 1991 - Jan 31, 2002
    Role: Co-Investigator
    METALLOPROTEINASES IN PERI-IMPLANTATION DEVELOPMENT
    NIH R01HD023539Feb 1, 1988 - Jan 31, 1994
    Role: Principal Investigator
    ENVIRONMENTAL MUTAGENESIS AND CARCINOGENESIS
    NIH T32ES007106Jul 1, 1982 - Jun 30, 2003
    Role: Principal Investigator
    MULTIPURPOSE ARTHRITIS AND MUSCULOSKELETAL DISEASES CTR
    NIH P60AR020684Sep 15, 1977 - Dec 31, 2003
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Global Health
    Collapse Academic Senate

    Collapse Featured Content 
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Leveraging microenvironmental synthetic lethalities to treat cancer. J Clin Invest. 2021 03 15; 131(6). Metcalf KJ, Alazzeh A, Werb Z, Weaver VM. PMID: 33720045.
      View in: PubMed   Mentions: 3     Fields:    
    2. Synthetic Tuning of Domain Stoichiometry in Nanobody-Enzyme Megamolecules. Bioconjug Chem. 2021 01 20; 32(1):143-152. Metcalf KJ, Kimmel BR, Sykora DJ, Modica JA, Parker KA, Berens E, Dai R, Dravid VP, Werb Z, Mrksich M. PMID: 33301672.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression. Nat Mater. 2021 04; 20(4):548-559. Maller O, Drain AP, Barrett AS, Borgquist S, Ruffell B, Zakharevich I, Pham TT, Gruosso T, Kuasne H, Lakins JN, Acerbi I, Barnes JM, Nemkov T, Chauhan A, Gruenberg J, Nasir A, Bjarnadottir O, Werb Z, Kabos P, Chen YY, Hwang ES, Park M, Coussens LM, Nelson AC, Hansen KC, Weaver VM. PMID: 33257795.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    4. Concepts of extracellular matrix remodelling in tumour progression and metastasis. Nat Commun. 2020 10 09; 11(1):5120. Winkler J, Abisoye-Ogunniyan A, Metcalf KJ, Werb Z. PMID: 33037194.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    5. LGR5 in breast cancer and ductal carcinoma in situ: a diagnostic and prognostic biomarker and a therapeutic target. BMC Cancer. 2020 Jun 10; 20(1):542. Hagerling C, Owyong M, Sitarama V, Wang CY, Lin C, van den Bijgaart RJE, Koopman CD, Brenot A, Nanjaraj A, Wärnberg F, Jirström K, Klein OD, Werb Z, Plaks V. PMID: 32522170.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    6. Transcriptional diversity and bioenergetic shift in human breast cancer metastasis revealed by single-cell RNA sequencing. Nat Cell Biol. 2020 03; 22(3):310-320. Davis RT, Blake K, Ma D, Gabra MBI, Hernandez GA, Phung AT, Yang Y, Maurer D, Lefebvre AEYT, Alshetaiwi H, Xiao Z, Liu J, Locasale JW, Digman MA, Mjolsness E, Kong M, Werb Z, Lawson DA. PMID: 32144411.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    7. Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression. Dev Cell. 2020 03 09; 52(5):591-604.e6. Marsh T, Kenific CM, Suresh D, Gonzalez H, Shamir ER, Mei W, Tankka A, Leidal AM, Kalavacherla S, Woo K, Werb Z, Debnath J. PMID: 32084360.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    8. A framework for advancing our understanding of cancer-associated fibroblasts. Nat Rev Cancer. 2020 03; 20(3):174-186. Sahai E, Astsaturov I, Cukierman E, DeNardo DG, Egeblad M, Evans RM, Fearon D, Greten FR, Hingorani SR, Hunter T, Hynes RO, Jain RK, Janowitz T, Jorgensen C, Kimmelman AC, Kolonin MG, Maki RG, Powers RS, Puré E, Ramirez DC, Scherz-Shouval R, Sherman MH, Stewart S, Tlsty TD, Tuveson DA, Watt FM, Weaver V, Weeraratna AT, Werb Z. PMID: 31980749.
      View in: PubMed   Mentions: 301     Fields:    Translation:HumansAnimalsCells
    9. MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy. Life Sci Alliance. 2019 12; 2(6). Owyong M, Chou J, van den Bijgaart RJ, Kong N, Efe G, Maynard C, Talmi-Frank D, Solomonov I, Koopman C, Hadler-Olsen E, Headley M, Lin C, Wang CY, Sagi I, Werb Z, Plaks V. PMID: 31727800.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    10. Immune effector monocyte-neutrophil cooperation induced by the primary tumor prevents metastatic progression of breast cancer. Proc Natl Acad Sci U S A. 2019 10 22; 116(43):21704-21714. Hagerling C, Gonzalez H, Salari K, Wang CY, Lin C, Robles I, van Gogh M, Dejmek A, Jirström K, Werb Z. PMID: 31591235.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    11. MULTI-seq: sample multiplexing for single-cell RNA sequencing using lipid-tagged indices. Nat Methods. 2019 07; 16(7):619-626. McGinnis CS, Patterson DM, Winkler J, Conrad DN, Hein MY, Srivastava V, Hu JL, Murrow LM, Weissman JS, Werb Z, Chow ED, Gartner ZJ. PMID: 31209384.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    12. Tumour heterogeneity and metastasis at single-cell resolution. Nat Cell Biol. 2018 12; 20(12):1349-1360. Lawson DA, Kessenbrock K, Davis RT, Pervolarakis N, Werb Z. PMID: 30482943.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansCells
    13. Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy. Cancer Cell. 2018 10 08; 34(4):561-578.e6. Medler TR, Murugan D, Horton W, Kumar S, Cotechini T, Forsyth AM, Leyshock P, Leitenberger JJ, Kulesz-Martin M, Margolin AA, Werb Z, Coussens LM. PMID: 30300579.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    14. Roles of the immune system in cancer: from tumor initiation to metastatic progression. Genes Dev. 2018 10 01; 32(19-20):1267-1284. Gonzalez H, Hagerling C, Werb Z. PMID: 30275043.
      View in: PubMed   Mentions: 280     Fields:    Translation:HumansCells
    15. Profiling human breast epithelial cells using single cell RNA sequencing identifies cell diversity. Nat Commun. 2018 05 23; 9(1):2028. Nguyen QH, Pervolarakis N, Blake K, Ma D, Davis RT, James N, Phung AT, Willey E, Kumar R, Jabart E, Driver I, Rock J, Goga A, Khan SA, Lawson DA, Werb Z, Kessenbrock K. PMID: 29795293.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansCells
    16. Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers. Genes Dev. 2018 02 01; 32(3-4):244-257. Takai K, Drain AP, Lawson DA, Littlepage LE, Karpuj M, Kessenbrock K, Le A, Inoue K, Weaver VM, Werb Z. PMID: 29483153.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    17. HIF signaling in osteoblast-lineage cells promotes systemic breast cancer growth and metastasis in mice. Proc Natl Acad Sci U S A. 2018 01 30; 115(5):E992-E1001. Devignes CS, Aslan Y, Brenot A, Devillers A, Schepers K, Fabre S, Chou J, Casbon AJ, Werb Z, Provot S. PMID: 29339479.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    18. Single-cell RNA sequencing reveals gene expression signatures of breast cancer-associated endothelial cells. Oncotarget. 2018 Feb 16; 9(13):10945-10961. Sun Z, Wang CY, Lawson DA, Kwek S, Velozo HG, Owyong M, Lai MD, Fong L, Wilson M, Su H, Werb Z, Cooke DL. PMID: 29541388.
      View in: PubMed   Mentions: 16     Fields:    
    19. Innate and acquired immune surveillance in the postdissemination phase of metastasis. FEBS J. 2018 02; 285(4):654-664. Gonzalez H, Robles I, Werb Z. PMID: 29131550.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    20. Endovascular Biopsy: In Vivo Cerebral Aneurysm Endothelial Cell Sampling and Gene Expression Analysis. Transl Stroke Res. 2018 02; 9(1):20-33. Cooke DL, McCoy DB, Halbach VV, Hetts SW, Amans MR, Dowd CF, Higashida RT, Lawson D, Nelson J, Wang CY, Kim H, Werb Z, McCulloch C, Hashimoto T, Su H, Sun Z. PMID: 28900857.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    21. Diverse regulation of mammary epithelial growth and branching morphogenesis through noncanonical Wnt signaling. Proc Natl Acad Sci U S A. 2017 03 21; 114(12):3121-3126. Kessenbrock K, Smith P, Steenbeek SC, Pervolarakis N, Kumar R, Minami Y, Goga A, Hinck L, Werb Z. PMID: 28270600.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    22. ZNF503/Zpo2 drives aggressive breast cancer progression by down-regulation of GATA3 expression. Proc Natl Acad Sci U S A. 2017 03 21; 114(12):3169-3174. Shahi P, Wang CY, Lawson DA, Slorach EM, Lu A, Yu Y, Lai MD, Gonzalez Velozo H, Werb Z. PMID: 28258171.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    23. Targeting the cancer-associated fibroblasts as a treatment in triple-negative breast cancer. Oncotarget. 2016 Dec 13; 7(50):82889-82901. Takai K, Le A, Weaver VM, Werb Z. PMID: 27756881.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    24. Systematic analysis of the achaete-scute complex-like gene signature in clinical cancer patients. Mol Clin Oncol. 2017 Jan; 6(1):7-18. Wang CY, Shahi P, Huang JT, Phan NN, Sun Z, Lin YC, Lai MD, Werb Z. PMID: 28123722.
      View in: PubMed   Mentions:
    25. PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression. Nat Med. 2016 11; 22(11):1321-1329. Horiuchi D, Camarda R, Zhou AY, Yau C, Momcilovic O, Balakrishnan S, Corella AN, Eyob H, Kessenbrock K, Lawson DA, Marsh LA, Anderton BN, Rohrberg J, Kunder R, Bazarov AV, Yaswen P, McManus MT, Rugo HS, Werb Z, Goga A. PMID: 27775705.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    26. Cancer-associated fibroblast-secreted CXCL16 attracts monocytes to promote stroma activation in triple-negative breast cancers. Nat Commun. 2016 10 11; 7:13050. Allaoui R, Bergenfelz C, Mohlin S, Hagerling C, Salari K, Werb Z, Anderson RL, Ethier SP, Jirström K, Påhlman S, Bexell D, Tahin B, Johansson ME, Larsson C, Leandersson K. PMID: 27725631.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    27. SPRY1 regulates mammary epithelial morphogenesis by modulating EGFR-dependent stromal paracrine signaling and ECM remodeling. Proc Natl Acad Sci U S A. 2016 09 27; 113(39):E5731-40. Koledova Z, Zhang X, Streuli C, Clarke RB, Klein OD, Werb Z, Lu P. PMID: 27621461.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    28. Deficiency in matrix metalloproteinase-2 results in long-term vascular instability and regression in the injured mouse spinal cord. Exp Neurol. 2016 Oct; 284(Pt A):50-62. Trivedi A, Zhang H, Ekeledo A, Lee S, Werb Z, Plant GW, Noble-Haeusslein LJ. PMID: 27468657.
      View in: PubMed   Mentions: 7     Fields:    
    29. Metalloproteinases: a Functional Pathway for Myeloid Cells. Microbiol Spectr. 2016 04; 4(2). Chou J, Chan MF, Werb Z. PMID: 27227311.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    30. Neutrophils: Critical components in experimental animal models of cancer. Semin Immunol. 2016 04; 28(2):197-204. Hagerling C, Werb Z. PMID: 26976824.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    31. Quantitative proteomic analyses of mammary organoids reveals distinct signatures after exposure to environmental chemicals. Proc Natl Acad Sci U S A. 2016 Mar 08; 113(10):E1343-51. Williams KE, Lemieux GA, Hassis ME, Olshen AB, Fisher SJ, Werb Z. PMID: 26903627.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    32. The Cleared Mammary Fat Pad Transplantation Assay for Mammary Epithelial Organogenesis. Cold Spring Harb Protoc. 2015 Dec 02; 2015(12):pdb.prot078071. Lawson DA, Werb Z, Zong Y, Goldstein AS. PMID: 26631119.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    33. p114RhoGEF governs cell motility and lumen formation during tubulogenesis through a ROCK-myosin-II pathway. J Cell Sci. 2015 Dec 01; 128(23):4317-27. Kim M, M Shewan A, Ewald AJ, Werb Z, Mostov KE. PMID: 26483385.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    34. Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells. Nature. 2015 Oct 01; 526(7571):131-5. Lawson DA, Bhakta NR, Kessenbrock K, Prummel KD, Yu Y, Takai K, Zhou A, Eyob H, Balakrishnan S, Wang CY, Yaswen P, Goga A, Werb Z. PMID: 26416748.
      View in: PubMed   Mentions: 292     Fields:    Translation:HumansAnimalsCells
    35. Adaptive Immune Regulation of Mammary Postnatal Organogenesis. Dev Cell. 2015 Sep 14; 34(5):493-504. Plaks V, Boldajipour B, Linnemann JR, Nguyen NH, Kersten K, Wolf Y, Casbon AJ, Kong N, van den Bijgaart RJ, Sheppard D, Melton AC, Krummel MF, Werb Z. PMID: 26321127.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    36. Endovascular biopsy: Strategy for analyzing gene expression profiles of individual endothelial cells obtained from human vessels✩. Biotechnol Rep (Amst). 2015 Sep; 7:157-165. Sun Z, Lawson DA, Sinclair E, Wang CY, Lai MD, Hetts SW, Higashida RT, Dowd CF, Halbach VV, Werb Z, Su H, Cooke DL. PMID: 26989654.
      View in: PubMed   Mentions:
    37. Animal Models of Corneal Injury. Bio Protoc. 2015 Jul 05; 5(13):e1516. Chan MF, Werb Z. PMID: 26191536.
      View in: PubMed   Mentions:
    38. Confocal Imaging of Myeloid Cells in the Corneal Stroma of Live Mice. Bio Protoc. 2015 Jul 05; 5(13):e1517. Chan MF, Werb Z. PMID: 26191537.
      View in: PubMed   Mentions:
    39. The Role of Stroma in Tumor Development. Cancer J. 2015 Jul-Aug; 21(4):250-3. Werb Z, Lu P. PMID: 26222075.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    40. RasGRP1 opposes proliferative EGFR-SOS1-Ras signals and restricts intestinal epithelial cell growth. Nat Cell Biol. 2015 Jun; 17(6):804-15. Depeille P, Henricks LM, van de Ven RA, Lemmens E, Wang CY, Matli M, Werb Z, Haigis KM, Donner D, Warren R, Roose JP. PMID: 26005835.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    41. Invasion and metastasis--recent advances and future challenges. J Mol Med (Berl). 2015 Apr; 93(4):361-8. Chambers AF, Werb Z. PMID: 25772709.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    42. The cancer stem cell niche: how essential is the niche in regulating stemness of tumor cells? Cell Stem Cell. 2015 Mar 05; 16(3):225-38. Plaks V, Kong N, Werb Z. PMID: 25748930.
      View in: PubMed   Mentions: 426     Fields:    Translation:HumansAnimalsCells
    43. Delineating CSF-1-dependent regulation of myeloid cell diversity in tumors. Oncoimmunology. 2015 Jun; 4(6):e1008871. Casbon AJ, Lohela M, Werb Z. PMID: 26155427.
      View in: PubMed   Mentions:
    44. Matrix metalloproteinases in stem cell regulation and cancer. Matrix Biol. 2015 May-Jul; 44-46:184-90. Kessenbrock K, Wang CY, Werb Z. PMID: 25661772.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    45. Invasive breast cancer reprograms early myeloid differentiation in the bone marrow to generate immunosuppressive neutrophils. Proc Natl Acad Sci U S A. 2015 Feb 10; 112(6):E566-75. Casbon AJ, Reynaud D, Park C, Khuc E, Gan DD, Schepers K, Passegué E, Werb Z. PMID: 25624500.
      View in: PubMed   Mentions: 123     Fields:    Translation:AnimalsCells
    46. Kynurenic acid is a nutritional cue that enables behavioral plasticity. Cell. 2015 Jan 15; 160(1-2):119-31. Lemieux GA, Cunningham KA, Lin L, Mayer F, Werb Z, Ashrafi K. PMID: 25594177.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    47. The Transcriptional Repressor ZNF503/Zeppo2 Promotes Mammary Epithelial Cell Proliferation and Enhances Cell Invasion. J Biol Chem. 2015 Feb 06; 290(6):3803-13. Shahi P, Slorach EM, Wang CY, Chou J, Lu A, Ruderisch A, Werb Z. PMID: 25538248.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    48. Remodelling the extracellular matrix in development and disease. Nat Rev Mol Cell Biol. 2014 Dec; 15(12):786-801. Bonnans C, Chou J, Werb Z. PMID: 25415508.
      View in: PubMed   Mentions: 883     Fields:    Translation:HumansAnimalsCells
    49. Balancing the innate immune system in tumor development. Trends Cell Biol. 2015 Apr; 25(4):214-20. Hagerling C, Casbon AJ, Werb Z. PMID: 25444276.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    50. Intravital imaging reveals distinct responses of depleting dynamic tumor-associated macrophage and dendritic cell subpopulations. Proc Natl Acad Sci U S A. 2014 Nov 25; 111(47):E5086-95. Lohela M, Casbon AJ, Olow A, Bonham L, Branstetter D, Weng N, Smith J, Werb Z. PMID: 25385645.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    51. A molecular switch for the orientation of epithelial cell polarization. Dev Cell. 2014 Oct 27; 31(2):171-87. Bryant DM, Roignot J, Datta A, Overeem AW, Kim M, Yu W, Peng X, Eastburn DJ, Ewald AJ, Werb Z, Mostov KE. PMID: 25307480.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    52. Real-time imaging of myeloid cells dynamics in ApcMin/+ intestinal tumors by spinning disk confocal microscopy. J Vis Exp. 2014 Oct 06; (92):51916. Bonnans C, Lohela M, Werb Z. PMID: 25350573.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    53. A multilevel model of postmenopausal breast cancer incidence. Cancer Epidemiol Biomarkers Prev. 2014 Oct; 23(10):2078-92. Hiatt RA, Porco TC, Liu F, Balke K, Balmain A, Barlow J, Braithwaite D, Diez-Roux AV, Kushi LH, Moasser MM, Werb Z, Windham GC, Rehkopf DH. PMID: 25017248.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    54. Efficacy of a metalloproteinase inhibitor in spinal cord injured dogs. PLoS One. 2014; 9(5):e96408. Levine JM, Cohen ND, Heller M, Fajt VR, Levine GJ, Kerwin SC, Trivedi AA, Fandel TM, Werb Z, Modestino A, Noble-Haeusslein LJ. PMID: 24788791.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    55. Collective invasion in breast cancer requires a conserved basal epithelial program. Cell. 2013 Dec 19; 155(7):1639-51. Cheung KJ, Gabrielson E, Werb Z, Ewald AJ. PMID: 24332913.
      View in: PubMed   Mentions: 281     Fields:    Translation:HumansAnimalsCells
    56. In silico molecular comparisons of C. elegans and mammalian pharmacology identify distinct targets that regulate feeding. PLoS Biol. 2013 Nov; 11(11):e1001712. Lemieux GA, Keiser MJ, Sassano MF, Laggner C, Mayer F, Bainton RJ, Werb Z, Roth BL, Shoichet BK, Ashrafi K. PMID: 24260022.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    57. Cancer. Circulating tumor cells. Science. 2013 Sep 13; 341(6151):1186-8. Plaks V, Koopman CD, Werb Z. PMID: 24031008.
      View in: PubMed   Mentions: 164     Fields:    Translation:HumansAnimalsCells
    58. Roadblocks to translational advances on metastasis research. Nat Med. 2013 Sep; 19(9):1104-9. Brabletz T, Lyden D, Steeg PS, Werb Z. PMID: 24013756.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    59. microRNA-mediated regulation of the tumor microenvironment. . 2013 Oct 15; 12(20):3262-71. Chou J, Shahi P, Werb Z. PMID: 24036551.
      View in: PubMed   Mentions:
    60. A role for matrix metalloproteinases in regulating mammary stem cell function via the Wnt signaling pathway. Cell Stem Cell. 2013 Sep 05; 13(3):300-13. Kessenbrock K, Dijkgraaf GJ, Lawson DA, Littlepage LE, Shahi P, Pieper U, Werb Z. PMID: 23871604.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    61. Protective effects of matrix metalloproteinase-12 following corneal injury. J Cell Sci. 2013 Sep 01; 126(Pt 17):3948-60. Chan MF, Li J, Bertrand A, Casbon AJ, Lin JH, Maltseva I, Werb Z. PMID: 23813962.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
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