Aaron Fields, PhD

TitleAssistant Professor
SchoolUCSF School of Medicine
DepartmentOrthopaedic Surgery
Address513 Parnassus Ave
San Francisco CA 94143
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    Collapse Biography 
    Collapse Education and Training
    University of DenverBS2005Mechanical Engineering
    University of California, BerkeleyPhD2010Mechanical Engineering
    University of California, San FranciscoPostdoctoral Fellowship2013Orthopaedic Surgery

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Role of the cartilage endplate in spinal disc degeneration
    NIH/NIAMS R01AR070198Apr 1, 2017 - Jan 31, 2022
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Dudli S, Enns-Bray W, Pauchard Y, Römmeler A, Fields A, Ferguson SJ, Helgason B. Larger vertebral endplate concavities cause higher failure load and work at failure under high-rate impact loading of rabbit spinal explants. J Mech Behav Biomed Mater. 2018 Apr; 80:104-110. PMID: 29414464.
      View in: PubMed
    2. Acevedo C, Sylvia M, Schaible E, Graham JL, Stanhope KL, Metz LN, Gludovatz B, Schwartz AV, Ritchie RO, Alliston TN, Havel PJ, Fields A. Contributions of Material Properties and Structure to Increased Bone Fragility for a Given Bone Mass in the UCD-T2DM Rat Model of Type 2 Diabetes. J Bone Miner Res. 2018 Jan 17. PMID: 29342321.
      View in: PubMed
    3. Berg-Johansen B, Jain D, Liebenberg EC, Fields A, Link TM, O'Neill CW, Lotz JC. Tidemark Avulsions are a Predominant Form of Endplate Irregularity. Spine (Phila Pa 1976). 2018 Jan 08. PMID: 29315127.
      View in: PubMed
    4. Berg-Johansen B, Han M, Fields A, Liebenberg EC, Lim BJ, Larson PE, Gunduz-Demir C, Kazakia GJ, Krug R, Lotz JC. Cartilage Endplate Thickness Variation Measured by Ultrashort Echo-Time MRI Is Associated with Adjacent Disc Degeneration. Spine (Phila Pa 1976). 2017 Oct 03. PMID: 28984733.
      View in: PubMed
    5. Berg-Johansen B, Fields A, Liebenberg EC, Li A, Lotz JC. Structure-function relationships at the human spinal disc-vertebra interface. J Orthop Res. 2018 Jan; 36(1):192-201. PMID: 28590060.
      View in: PubMed
    6. Millard SM, Wang L, Wattanachanya L, O'Carroll D, Fields A, Pang J, Kazakia G, Lotz JC, Nissenson RA. Role of Osteoblast Gi Signaling in Age-Related Bone Loss in Female Mice. Endocrinology. 2017 06 01; 158(6):1715-1726. PMID: 28407060.
      View in: PubMed
    7. Fowler TW, Acevedo C, Mazur CM, Hall-Glenn F, Fields A, Bale HA, Ritchie RO, Lotz JC, Vail TP, Alliston T. Glucocorticoid suppression of osteocyte perilacunar remodeling is associated with subchondral bone degeneration in osteonecrosis. Sci Rep. 2017 Mar 22; 7:44618. PMID: 28327602.
      View in: PubMed
    8. Dudli S, Fields A, Samartzis D, Karppinen J, Lotz JC. Pathobiology of Modic changes. Eur Spine J. 2016 11; 25(11):3723-3734. PMID: 26914098.
      View in: PubMed
    9. Nawathe S, Yang H, Fields A, Bouxsein ML, Keaveny TM. Theoretical effects of fully ductile versus fully brittle behaviors of bone tissue on the strength of the human proximal femur and vertebral body. J Biomech. 2015 May 01; 48(7):1264-9. PMID: 25828400.
      View in: PubMed
    10. Fields A, Berg-Johansen B, Metz LN, Miller S, La B, Liebenberg EC, Coughlin DG, Graham JL, Stanhope KL, Havel PJ, Lotz JC. Alterations in intervertebral disc composition, matrix homeostasis and biomechanical behavior in the UCD-T2DM rat model of type 2 diabetes. J Orthop Res. 2015 May; 33(5):738-46. PMID: 25641259; PMCID: PMC4408867.
    11. Wang J, Zhou B, Liu XS, Fields A, Sanyal A, Shi X, Adams M, Keaveny TM, Guo XE. Trabecular plates and rods determine elastic modulus and yield strength of human trabecular bone. Bone. 2015 Mar; 72:71-80. PMID: 25460571; PMCID: PMC4282941.
    12. Fields A, Han M, Krug R, Lotz JC. Cartilaginous end plates: Quantitative MR imaging with very short echo times-orientation dependence and correlation with biochemical composition. Radiology. 2015 Feb; 274(2):482-9. PMID: 25302832; PMCID: PMC4314292.
    13. Bailey JF, Fields A, Liebenberg E, Mattison JA, Lotz JC, Kramer PA. Comparison of vertebral and intervertebral disc lesions in aging humans and rhesus monkeys. Osteoarthritis Cartilage. 2014 Jul; 22(7):980-5. PMID: 24821664; PMCID: PMC4105267.
    14. Sahli F, Cuellar J, Pérez A, Fields A, Campos M, Ramos-Grez J. Structural parameters determining the strength of the porcine vertebral body affected by tumours. Comput Methods Biomech Biomed Engin. 2015; 18(8):890-9. PMID: 24460089.
      View in: PubMed
    15. Zhou B, Sherry Liu X, Wang J, Lucas Lu X, Fields A, Edward Guo X. Dependence of mechanical properties of trabecular bone on plate-rod microstructure determined by individual trabecula segmentation (ITS). J Biomech. 2014 Feb 07; 47(3):702-8. PMID: 24360196; PMCID: PMC3925244.
    16. Fields A, Rodriguez D, Gary KN, Liebenberg EC, Lotz JC. Influence of biochemical composition on endplate cartilage tensile properties in the human lumbar spine. J Orthop Res. 2014 Feb; 32(2):245-52. PMID: 24273192; PMCID: PMC4039641.
    17. Fields A, Liebenberg EC, Lotz JC. Innervation of pathologies in the lumbar vertebral end plate and intervertebral disc. Spine J. 2014 Mar 01; 14(3):513-21. PMID: 24139753; PMCID: PMC3945018.
    18. Lotz JC, Fields A, Liebenberg EC. The role of the vertebral end plate in low back pain. Global Spine J. 2013 Jun; 3(3):153-64. PMID: 24436866; PMCID: PMC3854605.
    19. Fields A, Sahli F, Rodriguez AG, Lotz JC. Seeing double: a comparison of microstructure, biomechanical function, and adjacent disc health between double- and single-layer vertebral endplates. Spine (Phila Pa 1976). 2012 Oct 01; 37(21):E1310-7. PMID: 22781006; PMCID: PMC3461110.
    20. Fields A, Nawathe S, Eswaran SK, Jekir MG, Adams MF, Papadopoulos P, Keaveny TM. Vertebral fragility and structural redundancy. J Bone Miner Res. 2012 Oct; 27(10):2152-8. PMID: 22623120; PMCID: PMC3440513.
    21. Yang H, Nawathe S, Fields A, Keaveny TM. Micromechanics of the human vertebral body for forward flexion. J Biomech. 2012 Aug 09; 45(12):2142-8. PMID: 22704826; PMCID: PMC3415303.
    22. Fields A, Keaveny TM. Trabecular architecture and vertebral fragility in osteoporosis. Curr Osteoporos Rep. 2012 Jun; 10(2):132-40. PMID: 22492119.
      View in: PubMed
    23. Fields A, Lee GL, Liu XS, Jekir MG, Guo XE, Keaveny TM. Influence of vertical trabeculae on the compressive strength of the human vertebra. J Bone Miner Res. 2011 Feb; 26(2):263-9. PMID: 20715186; PMCID: PMC3179351.
    24. Fields A, Lee GL, Keaveny TM. Mechanisms of initial endplate failure in the human vertebral body. J Biomech. 2010 Dec 01; 43(16):3126-31. PMID: 20817162; PMCID: PMC2991488.
    25. Fields A, Eswaran SK, Jekir MG, Keaveny TM. Role of trabecular microarchitecture in whole-vertebral body biomechanical behavior. J Bone Miner Res. 2009 Sep; 24(9):1523-30. PMID: 19338454; PMCID: PMC2730926.
    26. Eswaran SK, Fields A, Nagarathnam P, Keaveny TM. Multi-scale modeling of the human vertebral body: comparison of micro-CT based high-resolution and continuum-level models. Pac Symp Biocomput. 2009; 293-303. PMID: 19209709.
      View in: PubMed
    27. Laz PJ, Pal S, Fields A, Petrella AJ, Rullkoetter PJ. Effects of knee simulator loading and alignment variability on predicted implant mechanics: a probabilistic study. J Orthop Res. 2006 Dec; 24(12):2212-21. PMID: 17004268.
      View in: PubMed
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