Aaron Tward, MD, PhD
Biography UCLA | B.S. | 1999 | Microbiology and Molecular Genetics | UCLA | M.A. | 1999 | Microbiology and Molecular Genetics | UCSF | Ph.D. | 2005 | Biomedical Sciences | UCSF | M.D. | 2007 | Medicine | Harvard Medical School/Massachusetts Eye and Ear Infirmary | Residency | 2012 | Otolaryngology - Head and Neck Surgery | Harvard Medical School/Massachusetts Eye and Ear Infirmary | Fellowship | 2014 | Neurotology | University of California, San Francisco, CA | | 2021 | Diversity, Equity, and Inclusion Champion Training |
Overview Aaron D. Tward M.D., Ph.D., is a board-certified, fellowship-trained surgeon who specializes in the diagnosis and treatment of disorders of the ear and skull base.
Dr. Tward has particular clinical interests in cochlear implantation, management of benign and malignant tumors of the skull base including acoustic neuroma (vestibular schwannoma), surgery for chronic otitis media, stapedectomy, superior semi-circular canal dehiscence repair, and endoscopic surgery of the ear and skull base.
Dr. Tward’s research interests include tumor biology, the genetics and genomics of disorders of the head and neck, the development and physiology of the organs of hearing, and clinical outcomes of surgery of the ear and skull base.
Education and Training: • Undergraduate: University of California, Los Angeles, B.S. - Microbiology and Molecular Genetics • Graduate School: University of California, Los Angeles, M.A. - Microbiology and Molecular Genetics, Lab of A. Jake Lusis • Graduate School: University of California, San Francisco, Ph.D. - Biomedical Sciences, Lab of J. Michael Bishop • Medical School: University of California, San Francisco, M.D. • Internship: Brigham and Women’s Hospital, Harvard Medical School - General Surgery
• Residency: Otolaryngology – Head and Neck Surgery Harvard Medical School Residency Program in Otolaryngology Massachusetts Eye and Ear Infirmary Massachusetts General Hospital Brigham and Women’s Hospital Beth Israel-Deaconess Medical Center Boston Children’s Hospital
• Clinical Fellowship: Otology, Neurotology, and Skull Base Surgery Harvard Medical School Massachusetts Eye and Ear Infirmary Massachusetts General Hospital (Michael J. McKenna and Daniel J. Lee Fellowship directors)
• Post Doctoral: The Broad Institute of MIT and Harvard Lab of Todd R. Golub
• Diplomate, American Board of Otolaryngology • License, Medical Board of California
Bibliographic
Altmetrics Details
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication.
Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.)
Click a Field or Translation tag to filter the publications.
-
A Hierarchy of Proliferative and Migratory Keratinocytes Maintains the Tympanic Membrane. Cell Stem Cell. 2021 Feb 04; 28(2):315-330.e5.
Frumm SM, Yu SK, Chang J, Artichoker JA, Scaria SM, Lee KP, Byrnes LE, Sneddon JB, Tward AD. PMID: 33181078.
View in: PubMed Mentions: Fields:
-
A single-cell atlas and lineage analysis of the adult Drosophila ovary. Nat Commun. 2020 11 06; 11(1):5628.
Rust K, Byrnes LE, Yu KS, Park JS, Sneddon JB, Tward AD, Nystul TG. PMID: 33159074.
View in: PubMed Mentions: Fields: Translation: Animals
-
Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer. Elife. 2019 05 28; 8.
Adams CR, Htwe HH, Marsh T, Wang AL, Montoya ML, Subbaraj L, Tward AD, Bardeesy N, Perera RM. PMID: 31134896.
View in: PubMed Mentions: 7 Fields: Translation: HumansAnimalsCells
-
Adventitial Stromal Cells Define Group 2 Innate Lymphoid Cell Tissue Niches. Immunity. 2019 03 19; 50(3):707-722.e6.
Dahlgren MW, Jones SW, Cautivo KM, Dubinin A, Ortiz-Carpena JF, Farhat S, Yu KS, Lee K, Wang C, Molofsky AV, Tward AD, Krummel MF, Peng T, Molofsky AB. PMID: 30824323.
View in: PubMed Mentions: 30 Fields: Translation: AnimalsCells
-
Cellular Dynamics in Early Healing of Mouse Tympanic Membranes. Otol Neurotol. 2019 02; 40(2):e160-e166.
Chari DA, Frumm SM, Akil O, Tward AD. PMID: 30570602.
View in: PubMed Mentions: 1 Fields: Translation: Animals
-
Temporal Dynamics of Pseudoprogression After Gamma Knife Radiosurgery for Vestibular Schwannomas-A Retrospective Volumetric Study. Neurosurgery. 2019 01 01; 84(1):123-131.
Breshears JD, Chang J, Molinaro AM, Sneed PK, McDermott MW, Tward A, Theodosopoulos PV. PMID: 29518221.
View in: PubMed Mentions: 2 Fields: Translation: Humans
-
Impact of pretreatment growth on Tumor control for vestibular schwannomas following gamma knife. Laryngoscope. 2019 03; 129(3):743-747.
Chang J, Breshears JD, Molinaro AM, Sneed PK, McDermott MW, Theodosopoulos PV, Tward AD. PMID: 30408172.
View in: PubMed Mentions: Fields: Translation: Humans
-
Lineage dynamics of murine pancreatic development at single-cell resolution. Nat Commun. 2018 09 25; 9(1):3922.
Byrnes LE, Wong DM, Subramaniam M, Meyer NP, Gilchrist CL, Knox SM, Tward AD, Ye CJ, Sneddon JB. PMID: 30254276.
View in: PubMed Mentions: 17 Fields: Translation: HumansAnimalsCells
-
Oncogenic Signaling Pathways in The Cancer Genome Atlas. Cell. 2018 04 05; 173(2):321-337.e10.
Sanchez-Vega F, Mina M, Armenia J, Chatila WK, Luna A, La KC, Dimitriadoy S, Liu DL, Kantheti HS, Saghafinia S, Chakravarty D, Daian F, Gao Q, Bailey MH, Liang WW, Foltz SM, Shmulevich I, Ding L, Heins Z, Ochoa A, Gross B, Gao J, Zhang H, Kundra R, Kandoth C, Bahceci I, Dervishi L, Dogrusoz U, Zhou W, Shen H, Laird PW, Way GP, Greene CS, Liang H, Xiao Y, Wang C, Iavarone A, Berger AH, Bivona TG, Lazar AJ, Hammer GD, Giordano T, Kwong LN, McArthur G, Huang C, Tward AD, Frederick MJ, McCormick F, Meyerson M, Van Allen EM, Cherniack AD, Ciriello G, Sander C, Schultz N. PMID: 29625050.
View in: PubMed Mentions: 250 Fields: Translation: HumansCells
-
Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement. EMBO Mol Med. 2018 03; 10(3).
PMID: 29335337.
View in: PubMed Mentions: 18 Fields: Translation: HumansAnimalsCellsPHPublic Health
-
Duration and Timing of Transient Tumor Enlargement after Gamma Knife Radiosurgery for Vestibular Schwannomas. Journal of Neurological Surgery Part B Skull Base. 2018 Feb 1; 79(S 01):s1-s188.
Jonathan Breshears, Joseph Chang, Annette Molinaro, Penny Sneed, Michael Mcdermott, Aaron Tward, Philip Theodosopoulos. .
View in: Publisher Site Mentions:
-
Meningiomas of the Cerebellopontine Angle. Skull Base Surgery of the Posterior Fossa. 2018 Jan 1; 103-113.
Stephen T. Magill, Philip V. Theodosopoulos, Aaron D. Tward, Steven W. Cheung, Michael W. McDermott. .
View in: Publisher Site Mentions:
-
Defining epithelial cell dynamics and lineage relationships in the developing lacrimal gland. Development. 2017 07 01; 144(13):2517-2528.
PMID: 28576768.
View in: PubMed Mentions: 9 Fields: Translation: HumansAnimalsCells
-
Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer. Nat Med. 2016 04; 22(4):427-32.
PMID: 26950360.
View in: PubMed Mentions: 91 Fields: Translation: HumansCells
-
Auditory brainstem implantation in a 16-month-old boy with cochlear hypoplasia. Otol Neurotol. 2015 Apr; 36(4):618-24.
PMID: 25473959.
View in: PubMed Mentions: 3 Fields: Translation: HumansCTClinical Trials
-
Reciprocal interaction of Wnt and RXR-a pathways in hepatocyte development and hepatocellular carcinoma. PLoS One. 2015; 10(3):e0118480.
PMID: 25738607.
View in: PubMed Mentions: 5 Fields: Translation: HumansAnimalsCells
-
Intra-tumor genetic heterogeneity and mortality in head and neck cancer: analysis of data from the Cancer Genome Atlas. PLoS Med. 2015 Feb; 12(2):e1001786.
PMID: 25668320.
View in: PubMed Mentions: 81 Fields: Translation: HumansCells
-
Comprehensive genomic characterization of head and neck squamous cell carcinomas. Nature. 2015 Jan 29; 517(7536):576-82.
PMID: 25631445.
View in: PubMed Mentions: 908 Fields: Translation: HumansCells
-
Characterization of HPV and host genome interactions in primary head and neck cancers. Proc Natl Acad Sci U S A. 2014 Oct 28; 111(43):15544-9.
PMID: 25313082.
View in: PubMed Mentions: 103 Fields: Translation: HumansCells
-
Mutant-Allele Tumor Heterogeneity (MATH) Adds to Human Papillomavirus (HPV) Status in Predicting Outcome in Head-and-Neck Squamous Cell Carcinoma (HNSCC) Molecular Biology and Therapeutics. International Journal of Radiation Oncology • Biology • Physics. 2014 Feb 1; 88(2):467-468.
J.W. Rocco, A.D. Tward, Y. Ren, R.J. Hammon, E.A. Mroz. .
View in: Publisher Site Mentions:
-
High intratumor genetic heterogeneity is related to worse outcome in patients with head and neck squamous cell carcinoma. Cancer. 2013 Aug 15; 119(16):3034-42.
PMID: 23696076.
View in: PubMed Mentions: 72 Fields: Translation: Humans
-
The mutational landscape of head and neck squamous cell carcinoma. Science. 2011 Aug 26; 333(6046):1157-60.
Stransky N, Egloff AM, Tward AD, Kostic AD, Cibulskis K, Sivachenko A, Kryukov GV, Lawrence MS, Sougnez C, McKenna A, Shefler E, Ramos AH, Stojanov P, Carter SL, Voet D, Cortés ML, Auclair D, Berger MF, Saksena G, Guiducci C, Onofrio RC, Parkin M, Romkes M, Weissfeld JL, Seethala RR, Wang L, Rangel-Escareño C, Fernandez-Lopez JC, Hidalgo-Miranda A, Melendez-Zajgla J, Winckler W, Ardlie K, Gabriel SB, Meyerson M, Lander ES, Getz G, Golub TR, Garraway LA, Grandis JR. PMID: 21798893.
View in: PubMed Mentions: 926 Fields: Translation: HumansAnimalsCells
-
Integration of genomic analysis and in vivo transfection to identify sprouty 2 as a candidate tumor suppressor in liver cancer. Hepatology. 2008 Apr; 47(4):1200-10.
Lee SA, Ho C, Roy R, Kosinski C, Patil MA, Tward AD, Fridlyand J, Chen X. PMID: 18214995.
View in: PubMed Mentions: 45 Fields: Translation: HumansAnimals
-
The Functional Consequences of Polymorphisms in the Human PON1 Gene. The Paraoxonases: Their Role in Disease Development and Xenobiotic Metabolism. 2008 Jan 1; 267-281.
C.E. Furlong, R.J Richter, W.-F. Li, V.H. Brophy, C. Carlson, M. Rieder, D. Nickerson, L.G. Costa, J. Ranchalis, A.J. Lusis, D.M. Shih, A. Tward, G.P. Jarvik. .
View in: Publisher Site Mentions:
-
Distinct pathways of genomic progression to benign and malignant tumors of the liver. Proc Natl Acad Sci U S A. 2007 Sep 11; 104(37):14771-6.
Tward AD, Jones KD, Yant S, Cheung ST, Fan ST, Chen X, Kay MA, Wang R, Bishop JM. PMID: 17785413.
View in: PubMed Mentions: 90 Fields: Translation: HumansAnimals
-
Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC. Nat Med. 2007 Jul; 13(7):820-7.
Goga A, Yang D, Tward AD, Morgan DO, Bishop JM. PMID: 17589519.
View in: PubMed Mentions: 123 Fields: Translation: HumansAnimalsCells
-
Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation. Proc Natl Acad Sci U S A. 2006 Oct 03; 103(40):14842-7.
Sneddon JB, Zhen HH, Montgomery K, van de Rijn M, Tward AD, West R, Gladstone H, Chang HY, Morganroth GS, Oro AE, Brown PO. PMID: 17003113.
View in: PubMed Mentions: 104 Fields: Translation: HumansCells
-
Trypanosoma congolense: paraoxonase 1 prolongs survival of infected mice. Exp Parasitol. 2006 Nov; 114(3):240-5.
Bhasin KK, Yu JM, Tward A, Shih D, Campbell DA, Lusis AJ. PMID: 16682028.
View in: PubMed Mentions: 2 Fields: Translation: HumansAnimals
-
Hepatocellular carcinoma in Txnip-deficient mice. Oncogene. 2006 Jun 15; 25(25):3528-36.
Sheth SS, Bodnar JS, Ghazalpour A, Thipphavong CK, Tsutsumi S, Tward AD, Demant P, Kodama T, Aburatani H, Lusis AJ. PMID: 16607285.
View in: PubMed Mentions: 54 Fields: Translation: Animals
-
Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism. Pharmacogenet Genomics. 2005 Aug; 15(8):589-98.
Cole TB, Walter BJ, Shih DM, Tward AD, Lusis AJ, Timchalk C, Richter RJ, Costa LG, Furlong CE. PMID: 16007003.
View in: PubMed Mentions: 31 Fields: Translation: HumansAnimals
-
Role of paraoxonase (PON1) status in pesticide sensitivity: genetic and temporal determinants. Neurotoxicology. 2005 Aug; 26(4):651-9.
Furlong CE, Cole TB, Jarvik GP, Pettan-Brewer C, Geiss GK, Richter RJ, Shih DM, Tward AD, Lusis AJ, Costa LG. PMID: 16112327.
View in: PubMed Mentions: 21 Fields: Translation: HumansAnimals
-
Paraoxonase 1 (PON1) status and risk of insecticide exposure. J Biochem Mol Toxicol. 2005; 19(3):182-3.
Furlong CE, Cole TB, Walter BJ, Shih DM, Tward A, Lusis AJ, Timchalk C, Richter RJ, Costa LG. PMID: 15977192.
View in: PubMed Mentions: 2 Fields: Translation: HumansAnimals
-
Genomic progression in mouse models for liver tumors. Cold Spring Harb Symp Quant Biol. 2005; 70:217-24.
Tward AD, Jones KD, Yant S, Kay MA, Wang R, Bishop JM. PMID: 16869757.
View in: PubMed Mentions: 8 Fields: Translation: HumansAnimalsCells
-
Systemic rather than local heme oxygenase-1 overexpression improves cardiac allograft outcomes in a new transgenic mouse. J Immunol. 2003 Aug 01; 171(3):1572-80.
Araujo JA, Meng L, Tward AD, Hancock WW, Zhai Y, Lee A, Ishikawa K, Iyer S, Buelow R, Busuttil RW, Shih DM, Lusis AJ, Kupiec-Weglinski JW. PMID: 12874251.
View in: PubMed Mentions: 25 Fields: Translation: Animals
-
Expression of human paraoxonase (PON1) during development. Pharmacogenetics. 2003 Jun; 13(6):357-64.
Cole TB, Jampsa RL, Walter BJ, Arndt TL, Richter RJ, Shih DM, Tward A, Lusis AJ, Jack RM, Costa LG, Furlong CE. PMID: 12777966.
View in: PubMed Mentions: 47 Fields: Translation: HumansAnimals
-
Decreased atherosclerotic lesion formation in human serum paraoxonase transgenic mice. Circulation. 2002 Jul 23; 106(4):484-90.
Tward A, Xia YR, Wang XP, Shi YS, Park C, Castellani LW, Lusis AJ, Shih DM. PMID: 12135950.
View in: PubMed Mentions: 92 Fields: Translation: HumansAnimals
-
MSJAMA. From grave robbing to gifting: cadaver supply in the United States. JAMA. 2002 Mar 06; 287(9):1183.
Tward AD, Patterson HA. PMID: 11879122.
View in: PubMed Mentions: 3 Fields: Translation: Humans
-
Catalytic efficiency determines the in-vivo efficacy of PON1 for detoxifying organophosphorus compounds. Pharmacogenetics. 2000 Dec; 10(9):767-79.
Li WF, Costa LG, Richter RJ, Hagen T, Shih DM, Tward A, Lusis AJ, Furlong CE. PMID: 11191881.
View in: PubMed Mentions: 62 Fields: Translation: HumansAnimalsCells
-
Cancer risk in ATM heterozygotes: a model of phenotypic and mechanistic differences between missense and truncating mutations. Mol Genet Metab. 1999 Dec; 68(4):419-23.
Gatti RA, Tward A, Concannon P. PMID: 10607471.
View in: PubMed Mentions: 47 Fields: Translation: Humans
This graph shows the total number of publications by year. To see the data as text, click here.
This graph shows the total number of publications by year. To return to the graph, click here.
Year | Publications |
---|
1999 | 1 | 2000 | 1 | 2002 | 2 | 2003 | 2 | 2005 | 4 | 2006 | 3 | 2007 | 2 | 2008 | 2 | 2011 | 1 | 2013 | 1 | 2014 | 2 | 2015 | 4 | 2016 | 1 | 2017 | 1 | 2018 | 6 | 2019 | 4 | 2020 | 2 |
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
newest
oldest
line numbers
double spacing
all authors
publication IDs
|
Derived automatically from this person's publications.
_
People in Profiles who have published with this person.
_
People who share similar concepts with this person.
_
Search Department
_
|