Adil Daud, MD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address550 16th. Street
San Francisco CA 94158
Phone415-353-7392
ORCID ORCID Icon0000-0002-6617-8421 Additional info
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    Collapse Biography 
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    Government Medical College, NagpurMBBS12/1985Medicine
    Cleveland Clinic, Cleveland, OHPost Doc Fellowship12/1989Biochemistry
    Indiana University, Indianapolis INPost Doc Fellowship6/1994Molecular Biology
    Indiana University, Indianapolis INResidency06/1997Internal Medicine

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    Immune therapy and Clinical Trials

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Intratumoral Electroporation of Plasmid Encoded IL12 and Membrane-Anchored Anti-CD3 Increases Systemic Tumor Immunity. Mol Cancer Res. 2022 06 03; 20(6):983-995. Han M, Nguyen B, Lee JY, Browning E, Zhang J, Mukhopadhyay A, Gujar R, Salazar J, Hermiz R, Svenson L, Rolig AS, Redmond WL, Algazi AP, Daud AI, Canton DA, Twitty CG. PMID: 35302641.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Intratumoral therapies and in-situ vaccination for melanoma. Hum Vaccin Immunother. 2022 05 31; 18(3):1890512. Huppert LA, Daud AI. PMID: 35559766; PMCID: PMC9116417.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    3. Amplification of the CXCR3/CXCL9 axis via intratumoral electroporation of plasmid CXCL9 synergizes with plasmid IL-12 therapy to elicit robust anti-tumor immunity. Mol Ther Oncolytics. 2022 Jun 16; 25:174-188. Lee JY, Nguyen B, Mukhopadhyay A, Han M, Zhang J, Gujar R, Salazar J, Hermiz R, Svenson L, Browning E, Lyerly HK, Canton DA, Fisher D, Daud A, Algazi A, Skitzki J, Twitty CG. PMID: 35592387; PMCID: PMC9092072.
      View in: PubMed   Mentions:
    4. TCR-sequencing in cancer and autoimmunity: barcodes and beyond. Trends Immunol. 2022 03; 43(3):180-194. Pauken KE, Lagattuta KA, Lu BY, Lucca LE, Daud AI, Hafler DA, Kluger HM, Raychaudhuri S, Sharpe AH. PMID: 35090787; PMCID: PMC8882139.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Discovering dominant tumor immune archetypes in a pan-cancer census. Cell. 2022 01 06; 185(1):184-203.e19. Combes AJ, Samad B, Tsui J, Chew NW, Yan P, Reeder GC, Kushnoor D, Shen A, Davidson B, Barczak AJ, Adkisson M, Edwards A, Naser M, Barry KC, Courau T, Hammoudi T, Argüello RJ, Rao AA, Olshen AB, Immunoprofiler Consortium, Cai C, Zhan J, Davis KC, Kelley RK, Chapman JS, Atreya CE, Patel A, Daud AI, Ha P, Diaz AA, Kratz JR, Collisson EA, Fragiadakis GK, Erle DJ, Boissonnas A, Asthana S, Chan V, Krummel MF. PMID: 34963056; PMCID: PMC8862608.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    6. Response to PD-1 Immunotherapy in Metastatic Spiradenocarcinoma. JCO Precis Oncol. 2021 11; 5:340-343. Wu C, Chow M, Temby M, McCalmont TH, Daud A. PMID: 34994598.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Long-term outcomes in patients with advanced melanoma who had initial stable disease with pembrolizumab in KEYNOTE-001 and KEYNOTE-006. Eur J Cancer. 2021 11; 157:391-402. Hamid O, Robert C, Daud A, Carlino MS, Mitchell TC, Hersey P, Schachter J, Long GV, Hodi FS, Wolchok JD, Arance A, Grob JJ, Joshua AM, Weber JS, Mortier L, Jensen E, Diede SJ, Moreno BH, Ribas A. PMID: 34571336; PMCID: PMC9350885.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    8. Layilin Anchors Regulatory T Cells in Skin. J Immunol. 2021 10 01; 207(7):1763-1775. Mehta P, Gouirand V, Boda DP, Zhang J, Gearty SV, Zirak B, Lowe MM, Clancy S, Boothby I, Mahuron KM, Fries A, Krummel MF, Mankoo P, Chang HW, Liu J, Moreau JM, Scharschmidt TC, Daud A, Kim E, Neuhaus IM, Harris HW, Liao W, Rosenblum MD. PMID: 34470859; PMCID: PMC8489406.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    9. Tissue-specific Tregs in cancer metastasis: opportunities for precision immunotherapy. Cell Mol Immunol. 2022 01; 19(1):33-45. Huppert LA, Green MD, Kim L, Chow C, Leyfman Y, Daud AI, Lee JC. PMID: 34417572; PMCID: PMC8752797.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    10. Should Sentinel Lymph Node Biopsy Status Guide Adjuvant Radiation Therapy in Patients With Merkel Cell Carcinoma? Adv Radiat Oncol. 2021 Nov-Dec; 6(6):100764. Ahmad TR, Vasudevan HN, Lazar AA, Chan JW, George JR, Alvarado MD, Yu SS, Daud A, Yom SS. PMID: 34485762; PMCID: PMC8408430.
      View in: PubMed   Mentions:
    11. The Liver-Immunity Nexus and Cancer Immunotherapy. Clin Cancer Res. 2022 01 01; 28(1):5-12. Lee JC, Green MD, Huppert LA, Chow C, Pierce RH, Daud AI. PMID: 34285059; PMCID: PMC8897983.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    12. Pembrolizumab and Ipilimumab as Second-Line Therapy for Advanced Melanoma. J Clin Oncol. 2021 08 20; 39(24):2637-2639. Huppert LA, Daud AI. PMID: 34138634.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Single-cell analyses identify circulating anti-tumor CD8 T cells and markers for their enrichment. J Exp Med. 2021 04 05; 218(4). Pauken KE, Shahid O, Lagattuta KA, Mahuron KM, Luber JM, Lowe MM, Huang L, Delaney C, Long JM, Fung ME, Newcomer K, Tsai KK, Chow M, Guinn S, Kuchroo JR, Burke KP, Schenkel JM, Rosenblum MD, Daud AI, Sharpe AH, Singer M. PMID: 33651880; PMCID: PMC7933992.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    14. Three-year survival, correlates and salvage therapies in patients receiving first-line pembrolizumab for advanced Merkel cell carcinoma. J Immunother Cancer. 2021 04; 9(4). Nghiem P, Bhatia S, Lipson EJ, Sharfman WH, Kudchadkar RR, Brohl AS, Friedlander PA, Daud A, Kluger HM, Reddy SA, Boulmay BC, Riker A, Burgess MA, Hanks BA, Olencki T, Kendra K, Church C, Akaike T, Ramchurren N, Shinohara MM, Salim B, Taube JM, Jensen E, Kalabis M, Fling SP, Homet Moreno B, Sharon E, Cheever MA, Topalian SL. PMID: 33879601; PMCID: PMC8061836.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    15. The State of Melanoma: Emergent Challenges and Opportunities. Clin Cancer Res. 2021 05 15; 27(10):2678-2697. Atkins MB, Curiel-Lewandrowski C, Fisher DE, Swetter SM, Tsao H, Aguirre-Ghiso JA, Soengas MS, Weeraratna AT, Flaherty KT, Herlyn M, Sosman JA, Tawbi HA, Pavlick AC, Cassidy PB, Chandra S, Chapman PB, Daud A, Eroglu Z, Ferris LK, Fox BA, Gershenwald JE, Gibney GT, Grossman D, Hanks BA, Hanniford D, Hernando E, Jeter JM, Johnson DB, Khleif SN, Kirkwood JM, Leachman SA, Mays D, Nelson KC, Sondak VK, Sullivan RJ, Merlino G, Melanoma Research Foundation. PMID: 33414132; PMCID: PMC8127340.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    16. Long-term safety of pembrolizumab monotherapy and relationship with clinical outcome: A landmark analysis in patients with advanced melanoma. Eur J Cancer. 2021 02; 144:182-191. Robert C, Hwu WJ, Hamid O, Ribas A, Weber JS, Daud AI, Hodi FS, Wolchok JD, Mitchell TC, Hersey P, Dronca R, Joseph RW, Boutros C, Min L, Long GV, Schachter J, Puzanov I, Dummer R, Lin J, Ibrahim N, Diede SJ, Carlino MS, Joshua AM. PMID: 33360855; PMCID: PMC8388128.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    17. Continuous versus intermittent BRAF and MEK inhibition in patients with BRAF-mutated melanoma: a randomized phase 2 trial. Nat Med. 2020 10; 26(10):1564-1568. Algazi AP, Othus M, Daud AI, Lo RS, Mehnert JM, Truong TG, Conry R, Kendra K, Doolittle GC, Clark JI, Messino MJ, Moore DF, Lao C, Faller BA, Govindarajan R, Harker-Murray A, Dreisbach L, Moon J, Grossmann KF, Ribas A. PMID: 33020646; PMCID: PMC8063889.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCTClinical Trials
    18. Regulatory T cell control of systemic immunity and immunotherapy response in liver metastasis. Sci Immunol. 2020 10 02; 5(52). Lee JC, Mehdizadeh S, Smith J, Young A, Mufazalov IA, Mowery CT, Daud A, Bluestone JA. PMID: 33008914; PMCID: PMC7755924.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    19. Layilin augments integrin activation to promote antitumor immunity. J Exp Med. 2020 09 07; 217(9). Mahuron KM, Moreau JM, Glasgow JE, Boda DP, Pauli ML, Gouirand V, Panjabi L, Grewal R, Luber JM, Mathur AN, Feldman RM, Shifrut E, Mehta P, Lowe MM, Alvarado MD, Marson A, Singer M, Wells J, Jupp R, Daud AI, Rosenblum MD. PMID: 32539073; PMCID: PMC7478725.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    20. Prognostic Gene Expression Profiling in Cutaneous Melanoma: Identifying the Knowledge Gaps and Assessing the Clinical Benefit. JAMA Dermatol. 2020 09 01; 156(9):1004-1011. Grossman D, Okwundu N, Bartlett EK, Marchetti MA, Othus M, Coit DG, Hartman RI, Leachman SA, Berry EG, Korde L, Lee SJ, Bar-Eli M, Berwick M, Bowles T, Buchbinder EI, Burton EM, Chu EY, Curiel-Lewandrowski C, Curtis JA, Daud A, Deacon DC, Ferris LK, Gershenwald JE, Grossmann KF, Hu-Lieskovan S, Hyngstrom J, Jeter JM, Judson-Torres RL, Kendra KL, Kim CC, Kirkwood JM, Lawson DH, Leming PD, Long GV, Marghoob AA, Mehnert JM, Ming ME, Nelson KC, Polsky D, Scolyer RA, Smith EA, Sondak VK, Stark MS, Stein JA, Thompson JA, Thompson JF, Venna SS, Wei ML, Swetter SM. PMID: 32725204; PMCID: PMC8275355.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    21. Association of BRAF V600E/K Mutation Status and Prior BRAF/MEK Inhibition With Pembrolizumab Outcomes in Advanced Melanoma: Pooled Analysis of 3 Clinical Trials. JAMA Oncol. 2020 08 01; 6(8):1256-1264. Puzanov I, Ribas A, Robert C, Schachter J, Nyakas M, Daud A, Arance A, Carlino MS, O'Day SJ, Long GV, Margolin KA, Dummer R, Schadendorf D, Lutzky J, Ascierto PA, Tarhini A, Lin J, Mogg R, Homet Moreno B, Ibrahim N, Hamid O. PMID: 32672795; PMCID: PMC7366279.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCTClinical Trials
    22. Exhausted T cell signature predicts immunotherapy response in ER-positive breast cancer. Nat Commun. 2020 07 17; 11(1):3584. Terranova-Barberio M, Pawlowska N, Dhawan M, Moasser M, Chien AJ, Melisko ME, Rugo H, Rahimi R, Deal T, Daud A, Rosenblum MD, Thomas S, Munster PN. PMID: 32681091; PMCID: PMC7367885.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCellsCTClinical Trials
    23. Treatment of Metastatic Melanoma With Leptomeningeal Disease Using Intrathecal Immunotherapy. JCO Oncol Pract. 2020 11; 16(11):757-759. Huppert LA, Melisko ME, Glastonbury CM, Khanafshar E, Daud AI. PMID: 32603255.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    24. ASO Author Reflections: Tumor Immune Profiling-Based Neoadjuvant Immunotherapy for Locally Advanced Melanoma. Ann Surg Oncol. 2020 Oct; 27(11):4131-4132. Mahuron KM, Levine LS, Daud AI. PMID: 32488511.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Tumor Immune Profiling-Based Neoadjuvant Immunotherapy for Locally Advanced Melanoma. Ann Surg Oncol. 2020 Oct; 27(11):4122-4130. Levine LS, Mahuron KM, Tsai KK, Wu C, Mattis DM, Pauli ML, Oglesby A, Lee JC, Spitzer MH, Krummel MF, Algazi AP, Rosenblum MD, Alvarado M, Daud AI. PMID: 32488521; PMCID: PMC8317618.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    26. Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma. Clin Cancer Res. 2020 06 15; 26(12):2827-2837. Algazi AP, Twitty CG, Tsai KK, Le M, Pierce R, Browning E, Hermiz R, Canton DA, Bannavong D, Oglesby A, Francisco M, Fong L, Pittet MJ, Arlauckas SP, Garris C, Levine LP, Bifulco C, Ballesteros-Merino C, Bhatia S, Gargosky S, Andtbacka RHI, Fox BA, Rosenblum MD, Daud AI. PMID: 32376655.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCTClinical Trials
    27. Prognostic Biomarkers for Melanoma Immunotherapy. Curr Oncol Rep. 2020 02 11; 22(3):25. Twitty CG, Huppert LA, Daud AI. PMID: 32048065.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    28. Intratumoral delivery of tavokinogene telseplasmid yields systemic immune responses in metastatic melanoma patients. Ann Oncol. 2020 04; 31(4):532-540. Algazi A, Bhatia S, Agarwala S, Molina M, Lewis K, Faries M, Fong L, Levine LP, Franco M, Oglesby A, Ballesteros-Merino C, Bifulco CB, Fox BA, Bannavong D, Talia R, Browning E, Le MH, Pierce RH, Gargosky S, Tsai KK, Twitty C, Daud AI. PMID: 32147213.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCTClinical Trials
    29. Regulatory T cells use arginase 2 to enhance their metabolic fitness in tissues. JCI Insight. 2019 12 19; 4(24). Lowe MM, Boothby I, Clancy S, Ahn RS, Liao W, Nguyen DN, Schumann K, Marson A, Mahuron KM, Kingsbury GA, Liu Z, Munoz Sandoval P, Rodriguez RS, Pauli ML, Taravati K, Arron ST, Neuhaus IM, Harris HW, Kim EA, Shin US, Krummel MF, Daud A, Scharschmidt TC, Rosenblum MD. PMID: 31852848; PMCID: PMC6975275.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    30. Intratumoral Plasmid IL12 Electroporation Therapy in Patients with Advanced Melanoma Induces Systemic and Intratumoral T-cell Responses. Cancer Immunol Res. 2020 02; 8(2):246-254. Greaney SK, Algazi AP, Tsai KK, Takamura KT, Chen L, Twitty CG, Zhang L, Paciorek A, Pierce RH, Le MH, Daud AI, Fong L. PMID: 31852717; PMCID: PMC7002232.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCellsCTClinical Trials
    31. Intratumoral and Combination Therapy in Melanoma and Other Skin Cancers. Am J Clin Dermatol. 2019 Dec; 20(6):781-796. Oglesby A, Algazi AP, Daud AI. PMID: 31228012.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    32. Extended 5-Year Follow-up Results of a Phase Ib Study (BRIM7) of Vemurafenib and Cobimetinib in BRAF-Mutant Melanoma. Clin Cancer Res. 2020 01 01; 26(1):46-53. Ribas A, Daud A, Pavlick AC, Gonzalez R, Lewis KD, Hamid O, Gajewski TF, Puzanov I, Wongchenko M, Rooney I, Hsu JJ, Yan Y, Park E, McArthur GA. PMID: 31732523; PMCID: PMC6942621.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCTClinical Trials
    33. Intratumoral Delivery of Plasmid IL12 Via Electroporation Leads to Regression of Injected and Noninjected Tumors in Merkel Cell Carcinoma. Clin Cancer Res. 2020 02 01; 26(3):598-607. Bhatia S, Longino NV, Miller NJ, Kulikauskas R, Iyer JG, Ibrani D, Blom A, Byrd DR, Parvathaneni U, Twitty CG, Campbell JS, Le MH, Gargosky S, Pierce RH, Heller R, Daud AI, Nghiem P. PMID: 31582519.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    34. An analysis of genetic heterogeneity in untreated cancers. Nat Rev Cancer. 2019 11; 19(11):639-650. Reiter JG, Baretti M, Gerold JM, Makohon-Moore AP, Daud A, Iacobuzio-Donahue CA, Azad NS, Kinzler KW, Nowak MA, Vogelstein B. PMID: 31455892; PMCID: PMC6816333.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimals
    35. Pembrolizumab versus ipilimumab in advanced melanoma (KEYNOTE-006): post-hoc 5-year results from an open-label, multicentre, randomised, controlled, phase 3 study. Lancet Oncol. 2019 09; 20(9):1239-1251. Robert C, Ribas A, Schachter J, Arance A, Grob JJ, Mortier L, Daud A, Carlino MS, McNeil CM, Lotem M, Larkin JMG, Lorigan P, Neyns B, Blank CU, Petrella TM, Hamid O, Su SC, Krepler C, Ibrahim N, Long GV. PMID: 31345627.
      View in: PubMed   Mentions: 257     Fields:    Translation:HumansCTClinical Trials
    36. Neoadjuvant systemic therapy in melanoma: recommendations of the International Neoadjuvant Melanoma Consortium. Lancet Oncol. 2019 07; 20(7):e378-e389. Amaria RN, Menzies AM, Burton EM, Scolyer RA, Tetzlaff MT, Antdbacka R, Ariyan C, Bassett R, Carter B, Daud A, Faries M, Fecher LA, Flaherty KT, Gershenwald JE, Hamid O, Hong A, Kirkwood JM, Lo S, Margolin K, Messina J, Postow MA, Rizos H, Ross MI, Rozeman EA, Saw RPM, Sondak V, Sullivan RJ, Taube JM, Thompson JF, van de Wiel BA, Eggermont AM, Davies MA, International Neoadjuvant Melanoma Consortium members, Ascierto PA, Spillane AJ, van Akkooi ACJ, Wargo JA, Blank CU, Tawbi HA, Long GV. PMID: 31267972.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    37. PTCH1 Mutation in a Patient With Metastatic Undifferentiated Carcinoma With Clear Cell Change. J Natl Compr Canc Netw. 2019 07 01; 17(7):778-783. Tsai KK, Khurana N, McCalmont T, Daud A, Bastian B, Yeh I. PMID: 31319387.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    38. A dual pathway inhibition strategy using BKM120 combined with vemurafenib is poorly tolerated in BRAF V600E/K mutant advanced melanoma. Pigment Cell Melanoma Res. 2019 07; 32(4):603-606. Algazi AP, Rotow J, Posch C, Ortiz-Urda S, Pelayo A, Munster PN, Daud A. PMID: 30801911.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    39. Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4+ T Cell Immunity. Cell. 2019 04 18; 177(3):556-571.e16. Binnewies M, Mujal AM, Pollack JL, Combes AJ, Hardison EA, Barry KC, Tsui J, Ruhland MK, Kersten K, Abushawish MA, Spasic M, Giurintano JP, Chan V, Daud AI, Ha P, Ye CJ, Roberts EW, Krummel MF. PMID: 30955881; PMCID: PMC6954108.
      View in: PubMed   Mentions: 154     Fields:    Translation:HumansAnimalsCells
    40. Five-year survival outcomes for patients with advanced melanoma treated with pembrolizumab in KEYNOTE-001. Ann Oncol. 2019 04 01; 30(4):582-588. Hamid O, Robert C, Daud A, Hodi FS, Hwu WJ, Kefford R, Wolchok JD, Hersey P, Joseph R, Weber JS, Dronca R, Mitchell TC, Patnaik A, Zarour HM, Joshua AM, Zhao Q, Jensen E, Ahsan S, Ibrahim N, Ribas A. PMID: 30715153; PMCID: PMC6503622.
      View in: PubMed   Mentions: 223     Fields:    Translation:HumansCTClinical Trials
    41. Durable Tumor Regression and Overall Survival in Patients With Advanced Merkel Cell Carcinoma Receiving Pembrolizumab as First-Line Therapy. J Clin Oncol. 2019 03 20; 37(9):693-702. Nghiem P, Bhatia S, Lipson EJ, Sharfman WH, Kudchadkar RR, Brohl AS, Friedlander PA, Daud A, Kluger HM, Reddy SA, Boulmay BC, Riker AI, Burgess MA, Hanks BA, Olencki T, Margolin K, Lundgren LM, Soni A, Ramchurren N, Church C, Park SY, Shinohara MM, Salim B, Taube JM, Bird SR, Ibrahim N, Fling SP, Homet Moreno B, Sharon E, Cheever MA, Topalian SL. PMID: 30726175; PMCID: PMC6424137.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansCTClinical Trials
    42. Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade. Immunity. 2019 02 19; 50(2):477-492.e8. Pai CS, Huang JT, Lu X, Simons DM, Park C, Chang A, Tamaki W, Liu E, Roybal KT, Seagal J, Chen M, Hagihara K, Wei XX, DuPage M, Kwek SS, Oh DY, Daud A, Tsai KK, Wu C, Zhang L, Fasso M, Sachidanandam R, Jayaprakash A, Lin I, Casbon AJ, Kinsbury GA, Fong L. PMID: 30737146; PMCID: PMC6886475.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    43. Cytokines, Chemokines, and Other Biomarkers of Response for Checkpoint Inhibitor Therapy in Skin Cancer. Front Med (Lausanne). 2018; 5:351. Bridge JA, Lee JC, Daud A, Wells JW, Bluestone JA. PMID: 30631766; PMCID: PMC6315146.
      View in: PubMed   Mentions: 24  
    44. Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12. Immunity. 2018 12 18; 49(6):1148-1161.e7. Garris CS, Arlauckas SP, Kohler RH, Trefny MP, Garren S, Piot C, Engblom C, Pfirschke C, Siwicki M, Gungabeesoon J, Freeman GJ, Warren SE, Ong S, Browning E, Twitty CG, Pierce RH, Le MH, Algazi AP, Daud AI, Pai SI, Zippelius A, Weissleder R, Pittet MJ. PMID: 30552023; PMCID: PMC6301092.
      View in: PubMed   Mentions: 264     Fields:    Translation:HumansAnimalsCells
    45. Correction: Baseline Tumor Size Is an Independent Prognostic Factor for Overall Survival in Patients with Melanoma Treated with Pembrolizumab. Clin Cancer Res. 2018 Dec 01; 24(23):6098. Joseph RW, Elassaiss-Schaap J, Kefford R, Hwu WJ, Wolchok JD, Joshua AM, Ribas A, Hodi FS, Hamid O, Robert C, Daud A, Dronca R, Hersey P, Weber JS, Patnaik A, de Alwis DP, Perrone A, Zhang J, Kang SP, Ebbinghaus S, Anderson KM, Gangadhar TC. PMID: 30510087.
      View in: PubMed   Mentions: 9     Fields:    
    46. Antitumour activity of pembrolizumab in advanced mucosal melanoma: a post-hoc analysis of KEYNOTE-001, 002, 006. Br J Cancer. 2018 09; 119(6):670-674. Hamid O, Robert C, Ribas A, Hodi FS, Walpole E, Daud A, Arance AS, Brown E, Hoeller C, Mortier L, Schachter J, Long J, Ebbinghaus S, Ibrahim N, Butler M. PMID: 30202085; PMCID: PMC6173747.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCTClinical Trials
    47. Outcomes by line of therapy and programmed death ligand 1 expression in patients with advanced melanoma treated with pembrolizumab or ipilimumab in KEYNOTE-006: A randomised clinical trial. Eur J Cancer. 2018 09; 101:236-243. Carlino MS, Long GV, Schadendorf D, Robert C, Ribas A, Richtig E, Nyakas M, Caglevic C, Tarhini A, Blank C, Hoeller C, Bar-Sela G, Barrow C, Wolter P, Zhou H, Emancipator K, Jensen EH, Ebbinghaus S, Ibrahim N, Daud A. PMID: 30096704.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCTClinical Trials
    48. The lincRNA MIRAT binds to IQGAP1 and modulates the MAPK pathway in NRAS mutant melanoma. Sci Rep. 2018 Jul 19; 8(1):10902. Sanlorenzo M, Vujic I, Esteve-Puig R, Lai K, Vujic M, Lin K, Posch C, Dimon M, Moy A, Zekhtser M, Johnston K, Gho D, Ho W, Gajjala A, Oses Prieto J, Burlingame A, Daud A, Rappersberger K, Ortiz-Urda S. PMID: 30026510; PMCID: PMC6053443.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    49. Quantitative Spatial Profiling of PD-1/PD-L1 Interaction and HLA-DR/IDO-1 Predicts Improved Outcomes of Anti-PD-1 Therapies in Metastatic Melanoma. Clin Cancer Res. 2018 11 01; 24(21):5250-5260. Johnson DB, Bordeaux J, Kim JY, Vaupel C, Rimm DL, Ho TH, Joseph RW, Daud AI, Conry RM, Gaughan EM, Hernandez-Aya LF, Dimou A, Funchain P, Smithy J, Witte JS, McKee SB, Ko J, Wrangle JM, Dabbas B, Tangri S, Lameh J, Hall J, Markowitz J, Balko JM, Dakappagari N. PMID: 30021908; PMCID: PMC6214750.
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    50. A natural killer-dendritic cell axis defines checkpoint therapy-responsive tumor microenvironments. Nat Med. 2018 08; 24(8):1178-1191. Barry KC, Hsu J, Broz ML, Cueto FJ, Binnewies M, Combes AJ, Nelson AE, Loo K, Kumar R, Rosenblum MD, Alvarado MD, Wolf DM, Bogunovic D, Bhardwaj N, Daud AI, Ha PK, Ryan WR, Pollack JL, Samad B, Asthana S, Chan V, Krummel MF. PMID: 29942093; PMCID: PMC6475503.
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    51. Negative but not futile: MAGE-A3 immunotherapeutic for melanoma. Lancet Oncol. 2018 07; 19(7):852-853. Daud AI. PMID: 29908989.
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    52. Melanocytic Neoplasms, Introduction. Semin Cutan Med Surg. 2018 Jun; 37(2):87. Daud AI. PMID: 30040084.
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    53. Immunotherapy for melanoma. Semin Cutan Med Surg. 2018 Jun; 37(2):127-131. Cuevas LM, Daud AI. PMID: 30040090.
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    54. In-field and abscopal response after short-course radiation therapy in patients with metastatic Merkel cell carcinoma progressing on PD-1 checkpoint blockade: a case series. J Immunother Cancer. 2018 05 30; 6(1):43. Xu MJ, Wu S, Daud AI, Yu SS, Yom SS. PMID: 29848371; PMCID: PMC5977737.
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    55. Baseline Tumor Size Is an Independent Prognostic Factor for Overall Survival in Patients with Melanoma Treated with Pembrolizumab. Clin Cancer Res. 2018 10 15; 24(20):4960-4967. Joseph RW, Elassaiss-Schaap J, Kefford R, Hwu WJ, Wolchok JD, Joshua AM, Ribas A, Hodi FS, Hamid O, Robert C, Daud A, Dronca R, Hersey P, Weber JS, Patnaik A, de Alwis DP, Perrone A, Zhang J, Kang SP, Ebbinghaus S, Anderson KM, Gangadhar TC. PMID: 29685882; PMCID: PMC6916264.
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    56. The gut microbiota and immune checkpoint inhibitors. Hum Vaccin Immunother. 2018; 14(9):2178-2182. Humphries A, Daud A. PMID: 29494275; PMCID: PMC6183319.
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    57. Revisiting RECIST: the case of treatment beyond progression. Lancet Oncol. 2018 02; 19(2):157-159. Daud AI. PMID: 29361472.
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    58. Durable Complete Response After Discontinuation of Pembrolizumab in Patients With Metastatic Melanoma. J Clin Oncol. 2018 06 10; 36(17):1668-1674. Robert C, Ribas A, Hamid O, Daud A, Wolchok JD, Joshua AM, Hwu WJ, Weber JS, Gangadhar TC, Joseph RW, Dronca R, Patnaik A, Zarour H, Kefford R, Hersey P, Zhang J, Anderson J, Diede SJ, Ebbinghaus S, Hodi FS. PMID: 29283791.
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    59. Eighth American Joint Committee on Cancer (AJCC) melanoma classification: Let us reconsider stage III. Eur J Cancer. 2018 03; 91:168-170. Grob JJ, Schadendorf D, Lorigan P, Ascierto P, Larkin J, Nathan P, Robert C, Hauschild A, Weber J, Daud A, Hamid O, Dummer R, Hansson J, Hoeller C, Schachter J, Van Akkooi ACJ, Garbe C. PMID: 29224903.
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    60. Dual MEK/AKT inhibition with trametinib and GSK2141795 does not yield clinical benefit in metastatic NRAS-mutant and wild-type melanoma. Pigment Cell Melanoma Res. 2018 01; 31(1):110-114. Algazi AP, Esteve-Puig R, Nosrati A, Hinds B, Hobbs-Muthukumar A, Nandoskar P, Ortiz-Urda S, Chapman PB, Daud A. PMID: 28921907; PMCID: PMC8049535.
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    61. Final analysis of a randomised trial comparing pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory advanced melanoma. Eur J Cancer. 2017 11; 86:37-45. Hamid O, Puzanov I, Dummer R, Schachter J, Daud A, Schadendorf D, Blank C, Cranmer LD, Robert C, Pavlick AC, Gonzalez R, Hodi FS, Ascierto PA, Salama AKS, Margolin KA, Gangadhar TC, Wei Z, Ebbinghaus S, Ibrahim N, Ribas A. PMID: 28961465.
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    62. Efficacy and Safety of Pembrolizumab in Patients Enrolled in KEYNOTE-030 in the United States: An Expanded Access Program. J Immunother. 2017 Nov/Dec; 40(9):334-340. Gangadhar TC, Hwu WJ, Postow MA, Hamid O, Daud A, Dronca R, Joseph R, O'Day SJ, Hodi FS, Pavlick AC, Kluger H, Oxborough RP, Yang A, Gazdoiu M, Kush DA, Ebbinghaus S, Salama AKS. PMID: 29028788; PMCID: PMC5647109.
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    63. Melanoma treatment with intratumoral electroporation of tavokinogene telseplasmid (pIL-12, tavokinogene telseplasmid). Immunotherapy. 2017 12; 9(16):1309-1321. Canton DA, Shirley S, Wright J, Connolly R, Burkart C, Mukhopadhyay A, Twitty C, Qattan KE, Campbell JS, Le MH, Pierce RH, Gargosky S, Daud A, Algazi A. PMID: 29064334.
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    64. Phase II randomised discontinuation trial of cabozantinib in patients with advanced solid tumours. Eur J Cancer. 2017 11; 86:296-304. Schöffski P, Gordon M, Smith DC, Kurzrock R, Daud A, Vogelzang NJ, Lee Y, Scheffold C, Shapiro GI. PMID: 29059635.
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    65. Long-Term Outcomes in Patients With BRAF V600-Mutant Metastatic Melanoma Who Received Dabrafenib Combined With Trametinib. J Clin Oncol. 2018 03 01; 36(7):667-673. Long GV, Eroglu Z, Infante J, Patel S, Daud A, Johnson DB, Gonzalez R, Kefford R, Hamid O, Schuchter L, Cebon J, Sharfman W, McWilliams R, Sznol M, Redhu S, Gasal E, Mookerjee B, Weber J, Flaherty KT. PMID: 28991513.
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    66. Pembrolizumab versus ipilimumab for advanced melanoma: final overall survival results of a multicentre, randomised, open-label phase 3 study (KEYNOTE-006). Lancet. 2017 Oct 21; 390(10105):1853-1862. Schachter J, Ribas A, Long GV, Arance A, Grob JJ, Mortier L, Daud A, Carlino MS, McNeil C, Lotem M, Larkin J, Lorigan P, Neyns B, Blank C, Petrella TM, Hamid O, Zhou H, Ebbinghaus S, Ibrahim N, Robert C. PMID: 28822576.
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    67. Partially exhausted tumor-infiltrating lymphocytes predict response to combination immunotherapy. JCI Insight. 2017 Jul 20; 2(14). Loo K, Tsai KK, Mahuron K, Liu J, Pauli ML, Sandoval PM, Nosrati A, Lee J, Chen L, Hwang J, Levine LS, Krummel MF, Algazi AP, Pampaloni M, Alvarado MD, Rosenblum MD, Daud AI. PMID: 28724802; PMCID: PMC5518562.
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    68. Overall Survival in Patients With Advanced Melanoma Who Received Nivolumab Versus Investigator's Choice Chemotherapy in CheckMate 037: A Randomized, Controlled, Open-Label Phase III Trial. J Clin Oncol. 2018 02 01; 36(4):383-390. Larkin J, Minor D, D'Angelo S, Neyns B, Smylie M, Miller WH, Gutzmer R, Linette G, Chmielowski B, Lao CD, Lorigan P, Grossmann K, Hassel JC, Sznol M, Daud A, Sosman J, Khushalani N, Schadendorf D, Hoeller C, Walker D, Kong G, Horak C, Weber J. PMID: 28671856; PMCID: PMC6804912.
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    69. Efficacy and safety of nilotinib in patients with KIT-mutated metastatic or inoperable melanoma: final results from the global, single-arm, phase II TEAM trial. Ann Oncol. 2017 Jun 01; 28(6):1380-1387. Guo J, Carvajal RD, Dummer R, Hauschild A, Daud A, Bastian BC, Markovic SN, Queirolo P, Arance A, Berking C, Camargo V, Herchenhorn D, Petrella TM, Schadendorf D, Sharfman W, Testori A, Novick S, Hertle S, Nourry C, Chen Q, Hodi FS. PMID: 28327988; PMCID: PMC5452069.
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    70. Management of Treatment-Related Adverse Events with Agents Targeting the MAPK Pathway in Patients with Metastatic Melanoma. Oncologist. 2017 07; 22(7):823-833. Daud A, Tsai K. PMID: 28526719; PMCID: PMC5507648.
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    71. Liver Metastasis and Treatment Outcome with Anti-PD-1 Monoclonal Antibody in Patients with Melanoma and NSCLC. Cancer Immunol Res. 2017 05; 5(5):417-424. Tumeh PC, Hellmann MD, Hamid O, Tsai KK, Loo KL, Gubens MA, Rosenblum M, Harview CL, Taube JM, Handley N, Khurana N, Nosrati A, Krummel MF, Tucker A, Sosa EV, Sanchez PJ, Banayan N, Osorio JC, Nguyen-Kim DL, Chang J, Shintaku IP, Boasberg PD, Taylor EJ, Munster PN, Algazi AP, Chmielowski B, Dummer R, Grogan TR, Elashoff D, Hwang J, Goldinger SM, Garon EB, Pierce RH, Daud A. PMID: 28411193; PMCID: PMC5749922.
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    72. Evaluation of clinicopathological factors in PD-1 response: derivation and validation of a prediction scale for response to PD-1 monotherapy. Br J Cancer. 2017 Apr 25; 116(9):1141-1147. Nosrati A, Tsai KK, Goldinger SM, Tumeh P, Grimes B, Loo K, Algazi AP, Nguyen-Kim TDL, Levesque M, Dummer R, Hamid O, Daud A. PMID: 28324889; PMCID: PMC5418446.
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    73. Phase II randomised discontinuation trial of the MET/VEGF receptor inhibitor cabozantinib in metastatic melanoma. Br J Cancer. 2017 Feb 14; 116(4):432-440. Daud A, Kluger HM, Kurzrock R, Schimmoller F, Weitzman AL, Samuel TA, Moussa AH, Gordon MS, Shapiro GI. PMID: 28103611; PMCID: PMC5318966.
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    74. Indirect treatment comparison of dabrafenib plus trametinib versus vemurafenib plus cobimetinib in previously untreated metastatic melanoma patients. J Hematol Oncol. 2017 01 04; 10(1):3. Daud A, Gill J, Kamra S, Chen L, Ahuja A. PMID: 28052762; PMCID: PMC5209913.
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    75. Inhibitors of Cytotoxic T Lymphocyte Antigen 4 and Programmed Death 1/Programmed Death 1 Ligand for Metastatic Melanoma, Dual Versus Monotherapy-Summary of Advances and Future Directions for Studying These Drugs. Cancer J. 2017 Jan/Feb; 23(1):3-9. Loo K, Daud AI. PMID: 28114249.
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    76. Programmed Death-Ligand 1 Expression and Response to the Anti-Programmed Death 1 Antibody Pembrolizumab in Melanoma. J Clin Oncol. 2016 12; 34(34):4102-4109. Daud AI, Wolchok JD, Robert C, Hwu WJ, Weber JS, Ribas A, Hodi FS, Joshua AM, Kefford R, Hersey P, Joseph R, Gangadhar TC, Dronca R, Patnaik A, Zarour H, Roach C, Toland G, Lunceford JK, Li XN, Emancipator K, Dolled-Filhart M, Kang SP, Ebbinghaus S, Hamid O. PMID: 27863197; PMCID: PMC5562434.
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    77. Increased FDG avidity in lymphoid tissue associated with response to combined immune checkpoint blockade. J Immunother Cancer. 2016; 4:58. Tsai KK, Pampaloni MH, Hope C, Algazi AP, Ljung BM, Pincus L, Daud AI. PMID: 27660712; PMCID: PMC5028983.
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    78. Health-related quality of life in the randomised KEYNOTE-002 study of pembrolizumab versus chemotherapy in patients with ipilimumab-refractory melanoma. Eur J Cancer. 2016 11; 67:46-54. Schadendorf D, Dummer R, Hauschild A, Robert C, Hamid O, Daud A, van den Eertwegh A, Cranmer L, O'Day S, Puzanov I, Schachter J, Blank C, Salama A, Loquai C, Mehnert JM, Hille D, Ebbinghaus S, Kang SP, Zhou W, Ribas A. PMID: 27596353.
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    79. Clinical outcomes in metastatic uveal melanoma treated with PD-1 and PD-L1 antibodies. Cancer. 2016 Nov 15; 122(21):3344-3353. Algazi AP, Tsai KK, Shoushtari AN, Munhoz RR, Eroglu Z, Piulats JM, Ott PA, Johnson DB, Hwang J, Daud AI, Sosman JA, Carvajal RD, Chmielowski B, Postow MA, Weber JS, Sullivan RJ. PMID: 27533448; PMCID: PMC5767160.
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    80. Tumor immune profiling predicts response to anti-PD-1 therapy in human melanoma. J Clin Invest. 2016 09 01; 126(9):3447-52. Daud AI, Loo K, Pauli ML, Sanchez-Rodriguez R, Sandoval PM, Taravati K, Tsai K, Nosrati A, Nardo L, Alvarado MD, Algazi AP, Pampaloni MH, Lobach IV, Hwang J, Pierce RH, Gratz IK, Krummel MF, Rosenblum MD. PMID: 27525433; PMCID: PMC5004965.
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    81. A comparison of long-term outcomes between narrow and broad QRS complex patients treated with cardiac resynchronization therapy. Acta Cardiol. 2016 Jun; 71(3):323-30. Yap LB, Nguyen ST, Qadir F, Ma SK, Muhammad Z, Koh KW, Ali Z, Tay GS, Daud A, Said A, Sahat N, Rebo R, Tamin SS, Hussin A, Kaur S, Omar R. PMID: 27594128.
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    82. Part II: Checkpoint inhibitors in cancer therapy. Immunotherapy. 2016 06; 8(7):761-2. Daud AI. PMID: 27349974.
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    83. Emerging biomarkers as predictors to anti-PD1/PD-L1 therapies in advanced melanoma. Immunotherapy. 2016 06; 8(7):775-84. Loo K, Daud A. PMID: 27349977.
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    84. Part I: Checkpoint inhibitors in cancer therapy. Immunotherapy. 2016 Jun; 8(6):675-6. Daud AI. PMID: 27197535.
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    85. A Review of Novel Intralesional Therapies for Melanoma, With an Emphasis on a Potential Combination Approach. Oncology (Williston Park). 2016 May; 30(5):442-3. Chen L, Daud A. PMID: 27188675.
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    86. Pembrolizumab for melanoma- safety profile and future trends. Expert Opin Drug Saf. 2016 Jun; 15(6):727-9. Daud A, Nandoskar P. PMID: 27056241.
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    87. Association of Pembrolizumab With Tumor Response and Survival Among Patients With Advanced Melanoma. JAMA. 2016 Apr 19; 315(15):1600-9. Ribas A, Hamid O, Daud A, Hodi FS, Wolchok JD, Kefford R, Joshua AM, Patnaik A, Hwu WJ, Weber JS, Gangadhar TC, Hersey P, Dronca R, Joseph RW, Zarour H, Chmielowski B, Lawrence DP, Algazi A, Rizvi NA, Hoffner B, Mateus C, Gergich K, Lindia JA, Giannotti M, Li XN, Ebbinghaus S, Kang SP, Robert C. PMID: 27092830.
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    88. PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma. N Engl J Med. 2016 Jun 30; 374(26):2542-52. Nghiem PT, Bhatia S, Lipson EJ, Kudchadkar RR, Miller NJ, Annamalai L, Berry S, Chartash EK, Daud A, Fling SP, Friedlander PA, Kluger HM, Kohrt HE, Lundgren L, Margolin K, Mitchell A, Olencki T, Pardoll DM, Reddy SA, Shantha EM, Sharfman WH, Sharon E, Shemanski LR, Shinohara MM, Sunshine JC, Taube JM, Thompson JA, Townson SM, Yearley JH, Topalian SL, Cheever MA. PMID: 27093365; PMCID: PMC4927341.
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    89. Evaluation of Immune-Related Response Criteria and RECIST v1.1 in Patients With Advanced Melanoma Treated With Pembrolizumab. J Clin Oncol. 2016 05 01; 34(13):1510-7. Hodi FS, Hwu WJ, Kefford R, Weber JS, Daud A, Hamid O, Patnaik A, Ribas A, Robert C, Gangadhar TC, Joshua AM, Hersey P, Dronca R, Joseph R, Hille D, Xue D, Li XN, Kang SP, Ebbinghaus S, Perrone A, Wolchok JD. PMID: 26951310; PMCID: PMC5070547.
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    90. A phase I trial of panobinostat and epirubicin in solid tumors with a dose expansion in patients with sarcoma. Ann Oncol. 2016 05; 27(5):947-52. Thomas S, Aggarwal R, Jahan T, Ryan C, Troung T, Cripps AM, Raha P, Thurn KT, Chen S, Grabowsky JA, Park J, Hwang J, Daud A, Munster PN. PMID: 26903311; PMCID: PMC4843187.
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    91. Overall Survival and Durable Responses in Patients With BRAF V600-Mutant Metastatic Melanoma Receiving Dabrafenib Combined With Trametinib. J Clin Oncol. 2016 Mar 10; 34(8):871-8. Long GV, Weber JS, Infante JR, Kim KB, Daud A, Gonzalez R, Sosman JA, Hamid O, Schuchter L, Cebon J, Kefford RF, Lawrence D, Kudchadkar R, Burris HA, Falchook GS, Algazi A, Lewis K, Puzanov I, Ibrahim N, Sun P, Cunningham E, Kline AS, Del Buono H, McDowell DO, Patel K, Flaherty KT. PMID: 26811525.
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    92. Applying the WHO conceptual framework for the International Classification for Patient Safety to a surgical population. Int J Qual Health Care. 2016 Apr; 28(2):166-74. McElroy LM, Woods DM, Yanes AF, Skaro AI, Daud A, Curtis T, Wymore E, Holl JL, Abecassis MM, Ladner DP. PMID: 26803539; PMCID: PMC4833202.
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    93. Combined dabrafenib and trametinib therapy in metastatic melanoma and organ transplantation: Case report and review of the literature. JAAD Case Rep. 2015 Nov; 1(6):S23-5. Garrett GL, He SY, Sabouni N, Daud A, Arron ST. PMID: 27051803; PMCID: PMC4809575.
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    94. Pembrolizumab Cutaneous Adverse Events and Their Association With Disease Progression. JAMA Dermatol. 2015 Nov; 151(11):1206-1212. Sanlorenzo M, Vujic I, Daud A, Algazi A, Gubens M, Luna SA, Lin K, Quaglino P, Rappersberger K, Ortiz-Urda S. PMID: 26222619; PMCID: PMC5061067.
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    95. Nivolumab plus ipilimumab in the treatment of advanced melanoma. J Hematol Oncol. 2015 Oct 31; 8:123. Tsai KK, Daud AI. PMID: 26518223; PMCID: PMC4628394.
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    96. Current and Emerging Perspectives on Immunotherapy for Melanoma. Semin Oncol. 2015 Dec; 42 Suppl 3:S3-S11. Daud A. PMID: 26598057.
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    97. Combined BRAF and MEK Inhibition With Dabrafenib and Trametinib in BRAF V600-Mutant Colorectal Cancer. J Clin Oncol. 2015 Dec 01; 33(34):4023-31. Corcoran RB, Atreya CE, Falchook GS, Kwak EL, Ryan DP, Bendell JC, Hamid O, Messersmith WA, Daud A, Kurzrock R, Pierobon M, Sun P, Cunningham E, Little S, Orford K, Motwani M, Bai Y, Patel K, Venook AP, Kopetz S. PMID: 26392102; PMCID: PMC4669588.
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    98. Future of combination therapy with dabrafenib and trametinib in metastatic melanoma. Expert Opin Pharmacother. 2015; 16(14):2257-63. Zia Y, Chen L, Daud A. PMID: 26331795.
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    99. Randomized phase II study evaluating veliparib (ABT-888) with temozolomide in patients with metastatic melanoma. Ann Oncol. 2015 Oct; 26(10):2173-9. Middleton MR, Friedlander P, Hamid O, Daud A, Plummer R, Falotico N, Chyla B, Jiang F, McKeegan E, Mostafa NM, Zhu M, Qian J, McKee M, Luo Y, Giranda VL, McArthur GA. PMID: 26202595.
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    100. Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial. Lancet Oncol. 2015 Aug; 16(8):908-18. Ribas A, Puzanov I, Dummer R, Schadendorf D, Hamid O, Robert C, Hodi FS, Schachter J, Pavlick AC, Lewis KD, Cranmer LD, Blank CU, O'Day SJ, Ascierto PA, Salama AK, Margolin KA, Loquai C, Eigentler TK, Gangadhar TC, Carlino MS, Agarwala SS, Moschos SJ, Sosman JA, Goldinger SM, Shapira-Frommer R, Gonzalez R, Kirkwood JM, Wolchok JD, Eggermont A, Li XN, Zhou W, Zernhelt AM, Lis J, Ebbinghaus S, Kang SP, Daud A. PMID: 26115796; PMCID: PMC9004487.
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    101. Phase I Study of Pembrolizumab (MK-3475; Anti-PD-1 Monoclonal Antibody) in Patients with Advanced Solid Tumors. Clin Cancer Res. 2015 Oct 01; 21(19):4286-93. Patnaik A, Kang SP, Rasco D, Papadopoulos KP, Elassaiss-Schaap J, Beeram M, Drengler R, Chen C, Smith L, Espino G, Gergich K, Delgado L, Daud A, Lindia JA, Li XN, Pierce RH, Yearley JH, Wu D, Laterza O, Lehnert M, Iannone R, Tolcher AW. PMID: 25977344.
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    102. Pembrolizumab versus Ipilimumab in Advanced Melanoma. N Engl J Med. 2015 Jun 25; 372(26):2521-32. Robert C, Schachter J, Long GV, Arance A, Grob JJ, Mortier L, Daud A, Carlino MS, McNeil C, Lotem M, Larkin J, Lorigan P, Neyns B, Blank CU, Hamid O, Mateus C, Shapira-Frommer R, Kosh M, Zhou H, Ibrahim N, Ebbinghaus S, Ribas A, KEYNOTE-006 investigators. PMID: 25891173.
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    103. The Role of Anti-PD-1/PD-L1 Agents in Melanoma: Progress to Date. Drugs. 2015 Apr; 75(6):563-75. Tsai KK, Daud AI. PMID: 25802230.
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    104. The combination of axitinib followed by paclitaxel/carboplatin yields extended survival in advanced BRAF wild-type melanoma: results of a clinical/correlative prospective phase II clinical trial. Br J Cancer. 2015 Apr 14; 112(8):1326-31. Algazi AP, Cha E, Ortiz-Urda SM, McCalmont T, Bastian BC, Hwang J, Pampaloni MH, Behr S, Chong K, Cortez B, Quiroz A, Coakley F, Liu S, Daud AI. PMID: 25867272; PMCID: PMC4402449.
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    105. Phase I dose-escalation trial of checkpoint kinase 1 inhibitor MK-8776 as monotherapy and in combination with gemcitabine in patients with advanced solid tumors. J Clin Oncol. 2015 Mar 20; 33(9):1060-6. Daud AI, Ashworth MT, Strosberg J, Goldman JW, Mendelson D, Springett G, Venook AP, Loechner S, Rosen LS, Shanahan F, Parry D, Shumway S, Grabowsky JA, Freshwater T, Sorge C, Kang SP, Isaacs R, Munster PN. PMID: 25605849.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansCellsCTClinical Trials
    106. Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity. Cancer Cell. 2014 Dec 08; 26(6):938. Broz ML, Binnewies M, Boldajipour B, Nelson AE, Pollack JL, Erle DJ, Barczak A, Rosenblum MD, Daud A, Barber DL, Amigorena S, Van't Veer LJ, Sperling AI, Wolf DM, Krummel MF. PMID: 28898680.
      View in: PubMed   Mentions: 56     Fields:    
    107. Characteristics of pyrexia in BRAFV600E/K metastatic melanoma patients treated with combined dabrafenib and trametinib in a phase I/II clinical trial. Ann Oncol. 2015 Feb; 26(2):415-21. Menzies AM, Ashworth MT, Swann S, Kefford RF, Flaherty K, Weber J, Infante JR, Kim KB, Gonzalez R, Hamid O, Schuchter L, Cebon J, Sosman JA, Little S, Sun P, Aktan G, Ouellet D, Jin F, Long GV, Daud A. PMID: 25411413.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCTClinical Trials
    108. Involution of eruptive melanocytic nevi on combination BRAF and MEK inhibitor therapy. JAMA Dermatol. 2014 Nov; 150(11):1209-12. Chen FW, Tseng D, Reddy S, Daud AI, Swetter SM. PMID: 25142409.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    109. Comparative profile of cutaneous adverse events: BRAF/MEK inhibitor combination therapy versus BRAF monotherapy in melanoma. J Am Acad Dermatol. 2014 Dec; 71(6):1102-1109.e1. Sanlorenzo M, Choudhry A, Vujic I, Posch C, Chong K, Johnston K, Meier M, Osella-Abate S, Quaglino P, Daud A, Algazi A, Rappersberger K, Ortiz-Urda S. PMID: 25440439; PMCID: PMC4254519.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    110. Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity. Cancer Cell. 2014 Nov 10; 26(5):638-52. Broz ML, Binnewies M, Boldajipour B, Nelson AE, Pollack JL, Erle DJ, Barczak A, Rosenblum MD, Daud A, Barber DL, Amigorena S, Van't Veer LJ, Sperling AI, Wolf DM, Krummel MF. PMID: 25446897; PMCID: PMC4254577.
      View in: PubMed   Mentions: 403     Fields:    Translation:HumansAnimalsCells
    111. Combined BRAF (Dabrafenib) and MEK inhibition (Trametinib) in patients with BRAFV600-mutant melanoma experiencing progression with single-agent BRAF inhibitor. J Clin Oncol. 2014 Nov 20; 32(33):3697-704. Johnson DB, Flaherty KT, Weber JS, Infante JR, Kim KB, Kefford RF, Hamid O, Schuchter L, Cebon J, Sharfman WH, McWilliams RR, Sznol M, Lawrence DP, Gibney GT, Burris HA, Falchook GS, Algazi A, Lewis K, Long GV, Patel K, Ibrahim N, Sun P, Little S, Cunningham E, Sosman JA, Daud A, Gonzalez R. PMID: 25287827; PMCID: PMC4226803.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansCTClinical Trials
    112. Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial. Lancet. 2014 Sep 20; 384(9948):1109-17. Robert C, Ribas A, Wolchok JD, Hodi FS, Hamid O, Kefford R, Weber JS, Joshua AM, Hwu WJ, Gangadhar TC, Patnaik A, Dronca R, Zarour H, Joseph RW, Boasberg P, Chmielowski B, Mateus C, Postow MA, Gergich K, Elassaiss-Schaap J, Li XN, Iannone R, Ebbinghaus SW, Kang SP, Daud A. PMID: 25034862.
      View in: PubMed   Mentions: 699     Fields:    Translation:HumansCTClinical Trials
    113. Combination of vemurafenib and cobimetinib in patients with advanced BRAF(V600)-mutated melanoma: a phase 1b study. Lancet Oncol. 2014 Aug; 15(9):954-65. Ribas A, Gonzalez R, Pavlick A, Hamid O, Gajewski TF, Daud A, Flaherty L, Logan T, Chmielowski B, Lewis K, Kee D, Boasberg P, Yin M, Chan I, Musib L, Choong N, Puzanov I, McArthur GA. PMID: 25037139.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansCTClinical Trials
    114. Combinatorial approach to treatment of melanoma. Hematol Oncol Clin North Am. 2014 Jun; 28(3):601-12. Ashworth MT, Daud AI. PMID: 24880950.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    115. Melanoma, version 4.2014. J Natl Compr Canc Netw. 2014 May; 12(5):621-9. Coit DG, Thompson JA, Andtbacka R, Anker CJ, Bichakjian CK, Carson WE, Daniels GA, Daud A, Dimaio D, Fleming MD, Gonzalez R, Guild V, Halpern AC, Hodi FS, Kelley MC, Khushalani NI, Kudchadkar RR, Lange JR, Martini MC, Olszanski AJ, Ross MI, Salama A, Swetter SM, Tanabe KK, Trisal V, Urist MM, McMillian NR, Ho M, National Comprehensive Cancer Network. PMID: 24812131.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    116. Melanoma immunotherapy. Cancer Biol Ther. 2014 Jun 01; 15(6):665-74. Sanlorenzo M, Vujic I, Posch C, Dajee A, Yen A, Kim S, Ashworth M, Rosenblum MD, Algazi A, Osella-Abate S, Quaglino P, Daud A, Ortiz-Urda S. PMID: 24651672; PMCID: PMC4049781.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    117. Management of a patient with advanced BRAF-mutant melanoma. J Natl Compr Canc Netw. 2014 Mar 01; 12(3):315-9; quiz 319. Ashworth MT, Daud A. PMID: 24616537.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    118. The effects of a high-fat meal on single-dose vemurafenib pharmacokinetics. J Clin Pharmacol. 2014 Apr; 54(4):368-74. Ribas A, Zhang W, Chang I, Shirai K, Ernstoff MS, Daud A, Cowey CL, Daniels G, Seja E, O'Laco E, Glaspy JA, Chmielowski B, Hill T, Joe AK, Grippo JF. PMID: 24374975.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    119. PD-1 and PD-L1 antibodies for melanoma. Hum Vaccin Immunother. 2014; 10(11):3111-6. Tsai KK, Zarzoso I, Daud AI. PMID: 25625924; PMCID: PMC4514131.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    120. A phase I, randomized, open-label study of the multiple-dose pharmacokinetics of vemurafenib in patients with BRAF V600E mutation-positive metastatic melanoma. Cancer Chemother Pharmacol. 2014 Jan; 73(1):103-11. Grippo JF, Zhang W, Heinzmann D, Yang KH, Wong J, Joe AK, Munster P, Sarapa N, Daud A. PMID: 24178368.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCTClinical Trials
    121. Reply to M.-E. Percival et al and L.B. Saltz. J Clin Oncol. 2013 Jul 01; 31(19):2515-6. Daud AI. PMID: 23967490.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    122. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med. 2013 Jul 11; 369(2):134-44. Hamid O, Robert C, Daud A, Hodi FS, Hwu WJ, Kefford R, Wolchok JD, Hersey P, Joseph RW, Weber JS, Dronca R, Gangadhar TC, Patnaik A, Zarour H, Joshua AM, Gergich K, Elassaiss-Schaap J, Algazi A, Mateus C, Boasberg P, Tumeh PC, Chmielowski B, Ebbinghaus SW, Li XN, Kang SP, Ribas A. PMID: 23724846; PMCID: PMC4126516.
      View in: PubMed   Mentions: 1509     Fields:    Translation:HumansCTClinical Trials
    123. Melanoma, version 2.2013: featured updates to the NCCN guidelines. J Natl Compr Canc Netw. 2013 Apr 01; 11(4):395-407. Coit DG, Andtbacka R, Anker CJ, Bichakjian CK, Carson WE, Daud A, Dimaio D, Fleming MD, Guild V, Halpern AC, Hodi FS, Kelley MC, Khushalani NI, Kudchadkar RR, Lange JR, Lind A, Martini MC, Olszanski AJ, Pruitt SK, Ross MI, Swetter SM, Tanabe KK, Thompson JA, Trisal V, Urist MM, McMillian N, Ho M, National Comprehensive Cancer Network (NCCN). PMID: 23584343.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    124. Combined targeting of MEK and PI3K/mTOR effector pathways is necessary to effectively inhibit NRAS mutant melanoma in vitro and in vivo. Proc Natl Acad Sci U S A. 2013 Mar 05; 110(10):4015-20. Posch C, Moslehi H, Feeney L, Green GA, Ebaee A, Feichtenschlager V, Chong K, Peng L, Dimon MT, Phillips T, Daud AI, McCalmont TH, LeBoit PE, Ortiz-Urda S. PMID: 23431193; PMCID: PMC3593920.
      View in: PubMed   Mentions: 115     Fields:    Translation:HumansAnimalsCells
    125. Removing the unknown from the carcinoma of unknown primary. J Clin Oncol. 2013 Jan 10; 31(2):174-5. Daud AI. PMID: 23233703.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    126. Plasmid IL-12 electroporation in melanoma. Hum Vaccin Immunother. 2012 Nov 01; 8(11):1734-8. Cha E, Daud A. PMID: 23151447; PMCID: PMC3601150.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    127. Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations. N Engl J Med. 2012 11 01; 367(18):1694-703. Flaherty KT, Infante JR, Daud A, Gonzalez R, Kefford RF, Sosman J, Hamid O, Schuchter L, Cebon J, Ibrahim N, Kudchadkar R, Burris HA, Falchook G, Algazi A, Lewis K, Long GV, Puzanov I, Lebowitz P, Singh A, Little S, Sun P, Allred A, Ouellet D, Kim KB, Patel K, Weber J. PMID: 23020132; PMCID: PMC3549295.
      View in: PubMed   Mentions: 1065     Fields:    Translation:HumansCellsCTClinical Trials
    128. Management of pegylated interferon alpha toxicity in adjuvant therapy of melanoma. Expert Opin Biol Ther. 2012 Aug; 12(8):1087-99. Daud A, Soon C, Dummer R, Eggermont AM, Hwu WJ, Grob JJ, Garbe C, Hauschild A. PMID: 22694288.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    129. Cutting edge in medical management of cutaneous oncology. Semin Cutan Med Surg. 2012 Jun; 31(2):140-9. Chong K, Daud A, Ortiz-Urda S, Arron ST, UCSF High Risk Skin Cancer Program. PMID: 22640435; PMCID: PMC3367308.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    130. Melanoma. J Natl Compr Canc Netw. 2012 Mar; 10(3):366-400. Coit DG, Andtbacka R, Anker CJ, Bichakjian CK, Carson WE, Daud A, Dilawari RA, Dimaio D, Guild V, Halpern AC, Hodi FS, Kelley MC, Khushalani NI, Kudchadkar RR, Lange JR, Lind A, Martini MC, Olszanski AJ, Pruitt SK, Ross MI, Swetter SM, Tanabe KK, Thompson JA, Trisal V, Urist MM, National Comprehensive Cancer Network. PMID: 22393197.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    131. Beyond BRAF in melanoma. Curr Top Microbiol Immunol. 2012; 355:99-117. Daud A, Bastian BC. PMID: 21826607.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    132. Phase I study of bosutinib, a src/abl tyrosine kinase inhibitor, administered to patients with advanced solid tumors. Clin Cancer Res. 2012 Feb 15; 18(4):1092-100. Daud AI, Krishnamurthi SS, Saleh MN, Gitlitz BJ, Borad MJ, Gold PJ, Chiorean EG, Springett GM, Abbas R, Agarwal S, Bardy-Bouxin N, Hsyu PH, Leip E, Turnbull K, Zacharchuk C, Messersmith WA. PMID: 22179664.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCTClinical Trials
    133. Phase I clinical trial of the Src inhibitor dasatinib with dacarbazine in metastatic melanoma. Br J Cancer. 2012 Jan 03; 106(1):85-91. Algazi AP, Weber JS, Andrews SC, Urbas P, Munster PN, DeConti RC, Hwang J, Sondak VK, Messina JL, McCalmont T, Daud AI. PMID: 22127285; PMCID: PMC3251861.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCTClinical Trials
    134. BEAM trial: lighting the way ahead? J Clin Oncol. 2012 Jan 01; 30(1):6-7. Daud AI. PMID: 22124100.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    135. Preclinical and clinical activity of the topoisomerase I inhibitor, karenitecin, in melanoma. Expert Opin Investig Drugs. 2011 Nov; 20(11):1565-74. Munster PN, Daud AI. PMID: 21985236.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    136. Phase I trial of ALT-801, an interleukin-2/T-cell receptor fusion protein targeting p53 (aa264-272)/HLA-A*0201 complex, in patients with advanced malignancies. Clin Cancer Res. 2011 Dec 15; 17(24):7765-75. Fishman MN, Thompson JA, Pennock GK, Gonzalez R, Diez LM, Daud AI, Weber JS, Huang BY, Tang S, Rhode PR, Wong HC. PMID: 21994418; PMCID: PMC3972922.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCellsCTClinical Trials
    137. An isolated Merkel cell carcinoma metastasis at a distant cutaneous site presenting as a second 'primary' tumor. J Cutan Pathol. 2011 Oct; 38(10):801-7. Ahronowitz IZ, Daud AI, Leong SP, Shue EH, Bastian BC, McCalmont TH, Yu SS. PMID: 21883364.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    138. Cutaneous melanoma: a model to study cancer metastasis. J Surg Oncol. 2011 May 01; 103(6):538-49. Leong SP, Gershenwald JE, Soong SJ, Schadendorf D, Tarhini AA, Agarwala S, Hauschild A, Soon CW, Daud A, Kashani-Sabet M. PMID: 21480247.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    139. NRAS-mutant melanoma: response to chemotherapy. Arch Dermatol. 2011 May; 147(5):626-7. Soon CW, Algazi AP, Cha EN, Webb EM, Daud AI. PMID: 21576590.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    140. Tumor fistulization associated with targeted therapy: computed tomographic findings and clinical consequences. J Comput Assist Tomogr. 2011 Jan-Feb; 35(1):86-90. Chow H, Jung A, Talbott J, Lin AM, Daud AI, Coakley FV. PMID: 21245693; PMCID: PMC3675219.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    141. Phase II trial of sagopilone, a novel epothilone analog in metastatic melanoma. Br J Cancer. 2010 Nov 09; 103(10):1548-53. DeConti RC, Algazi AP, Andrews S, Urbas P, Born O, Stoeckigt D, Floren L, Hwang J, Weber J, Sondak VK, Daud AI. PMID: 20924376; PMCID: PMC2990578.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    142. Changes in dendritic cell phenotype after a new high-dose weekly schedule of interleukin-2 therapy for kidney cancer and melanoma. J Immunother. 2010 Oct; 33(8):817-27. Finkelstein SE, Carey T, Fricke I, Yu D, Goetz D, Gratz M, Dunn M, Urbas P, Daud A, DeConti R, Antonia S, Gabrilovich D, Fishman M. PMID: 20842055.
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    143. Treatment of cutaneous melanoma: current approaches and future prospects. Cancer Manag Res. 2010 Aug 17; 2:197-211. Algazi AP, Soon CW, Daud AI. PMID: 21188111; PMCID: PMC3004577.
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    144. Pharmacokinetic/pharmacodynamic analysis of adjuvant pegylated interferon α-2b in patients with resected high-risk melanoma. Cancer Chemother Pharmacol. 2011 Mar; 67(3):657-66. Daud AI, Xu C, Hwu WJ, Urbas P, Andrews S, Papadopoulos NE, Floren LC, Yver A, Deconti RC, Sondak VK. PMID: 20509027; PMCID: PMC3043235.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    145. New horizons in melanoma treatment: targeting molecular pathways. Ochsner J. 2010; 10(2):93-8. Soon CW, Algazi AP, Cha EN, Daud AI. PMID: 21603363; PMCID: PMC3096197.
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    146. Phase I trial of vorinostat and doxorubicin in solid tumours: histone deacetylase 2 expression as a predictive marker. Br J Cancer. 2009 Oct 06; 101(7):1044-50. Munster PN, Marchion D, Thomas S, Egorin M, Minton S, Springett G, Lee JH, Simon G, Chiappori A, Sullivan D, Daud A. PMID: 19738609; PMCID: PMC2768109.
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    147. Src activation in melanoma and Src inhibitors as therapeutic agents in melanoma. Melanoma Res. 2009 Jun; 19(3):167-75. Homsi J, Cubitt CL, Zhang S, Munster PN, Yu H, Sullivan DM, Jove R, Messina JL, Daud AI. PMID: 19434004.
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    148. Results of a phase III, randomized, placebo-controlled study of sorafenib in combination with carboplatin and paclitaxel as second-line treatment in patients with unresectable stage III or stage IV melanoma. J Clin Oncol. 2009 Jun 10; 27(17):2823-30. Hauschild A, Agarwala SS, Trefzer U, Hogg D, Robert C, Hersey P, Eggermont A, Grabbe S, Gonzalez R, Gille J, Peschel C, Schadendorf D, Garbe C, O'Day S, Daud A, White JM, Xia C, Patel K, Kirkwood JM, Keilholz U. PMID: 19349552.
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    149. Clinical and biological effects of valproic acid as a histone deacetylase inhibitor on tumor and surrogate tissues: phase I/II trial of valproic acid and epirubicin/FEC. Clin Cancer Res. 2009 Apr 01; 15(7):2488-96. Munster P, Marchion D, Bicaku E, Lacevic M, Kim J, Centeno B, Daud A, Neuger A, Minton S, Sullivan D. PMID: 19318486.
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    150. Potentiation of a topoisomerase I inhibitor, karenitecin, by the histone deacetylase inhibitor valproic acid in melanoma: translational and phase I/II clinical trial. Clin Cancer Res. 2009 Apr 01; 15(7):2479-87. Daud AI, Dawson J, DeConti RC, Bicaku E, Marchion D, Bastien S, Hausheer FA, Lush R, Neuger A, Sullivan DM, Munster PN. PMID: 19318485.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    151. Phase II trial of 17-allylamino-17-demethoxygeldanamycin in patients with metastatic melanoma. Clin Cancer Res. 2008 Dec 15; 14(24):8302-7. Solit DB, Osman I, Polsky D, Panageas KS, Daud A, Goydos JS, Teitcher J, Wolchok JD, Germino FJ, Krown SE, Coit D, Rosen N, Chapman PB. PMID: 19088048; PMCID: PMC2629404.
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    152. Phase I trial of interleukin-12 plasmid electroporation in patients with metastatic melanoma. J Clin Oncol. 2008 Dec 20; 26(36):5896-903. Daud AI, DeConti RC, Andrews S, Urbas P, Riker AI, Sondak VK, Munster PN, Sullivan DM, Ugen KE, Messina JL, Heller R. PMID: 19029422; PMCID: PMC2645111.
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    153. State of the science 60th anniversary review: 60 Years of advances in cutaneous melanoma epidemiology, diagnosis, and treatment, as reported in the journal Cancer. Cancer. 2008 Oct 01; 113(7 Suppl):1728-43. Demierre MF, Sabel MS, Margolin KA, Daud AI, Sondak VK. PMID: 18798543.
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    154. Phase I and pharmacokinetic study of YM155, a small-molecule inhibitor of survivin. J Clin Oncol. 2008 Nov 10; 26(32):5198-203. Tolcher AW, Mita A, Lewis LD, Garrett CR, Till E, Daud AI, Patnaik A, Papadopoulos K, Takimoto C, Bartels P, Keating A, Antonia S. PMID: 18824702; PMCID: PMC4879696.
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    155. A phase I and pharmacokinetic study of paclitaxel poliglumex and cisplatin in patients with advanced solid tumors. Cancer Chemother Pharmacol. 2009 Apr; 63(5):903-10. Verschraegen CF, Skubitz K, Daud A, Kudelka AP, Rabinowitz I, Allievi C, Eisenfeld A, Singer JW, Oldham FB. PMID: 18682950.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    156. Melanoma: promising new discoveries and treatment modalities for difficult clinical scenarios. Cancer Control. 2008 Jul; 15(3):192-4. Zager JS, Daud AI. PMID: 18596670.
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    157. Phenotypic and functional analysis of dendritic cells and clinical outcome in patients with high-risk melanoma treated with adjuvant granulocyte macrophage colony-stimulating factor. J Clin Oncol. 2008 Jul 01; 26(19):3235-41. Daud AI, Mirza N, Lenox B, Andrews S, Urbas P, Gao GX, Lee JH, Sondak VK, Riker AI, Deconti RC, Gabrilovich D. PMID: 18591558.
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    158. Activated stat-3 in melanoma. Cancer Control. 2008 Jul; 15(3):196-201. Messina JL, Yu H, Riker AI, Munster PN, Jove RL, Daud AI. PMID: 18596671.
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    159. The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis. BMC Med Genomics. 2008 Apr 28; 1:13. Riker AI, Enkemann SA, Fodstad O, Liu S, Ren S, Morris C, Xi Y, Howell P, Metge B, Samant RS, Shevde LA, Li W, Eschrich S, Daud A, Ju J, Matta J. PMID: 18442402; PMCID: PMC2408576.
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    160. Phase I trial of poly-L-glutamate camptothecin (CT-2106) administered weekly in patients with advanced solid malignancies. Clin Cancer Res. 2007 Oct 01; 13(19):5855-61. Homsi J, Simon GR, Garrett CR, Springett G, De Conti R, Chiappori AA, Munster PN, Burton MK, Stromatt S, Allievi C, Angiuli P, Eisenfeld A, Sullivan DM, Daud AI. PMID: 17908979.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    161. Spectrum of activity and mechanism of action of VEGF/PDGF inhibitors. Cancer Control. 2007 Jul; 14(3):285-94. Homsi J, Daud AI. PMID: 17615535.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    162. Phase I trial of histone deacetylase inhibition by valproic acid followed by the topoisomerase II inhibitor epirubicin in advanced solid tumors: a clinical and translational study. J Clin Oncol. 2007 May 20; 25(15):1979-85. Münster P, Marchion D, Bicaku E, Schmitt M, Lee JH, DeConti R, Simon G, Fishman M, Minton S, Garrett C, Chiappori A, Lush R, Sullivan D, Daud A. PMID: 17513804.
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    163. The Src signaling pathway: a potential target in melanoma and other malignancies. Expert Opin Ther Targets. 2007 Jan; 11(1):91-100. Homsi J, Cubitt C, Daud A. PMID: 17150037.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    164. Down-regulation of pro-apoptotic genes is an early event in the progression of malignant melanoma. Ann Surg Oncol. 2007 Apr; 14(4):1416-23. Jensen EH, Lewis JM, McLoughlin JM, Alvarado MD, Daud A, Messina J, Enkemann S, Yeatman TJ, Sondak VK, Riker AI. PMID: 17195911.
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    165. Increased bioavailability of intravenous versus oral CI-1033, a pan erbB tyrosine kinase inhibitor: results of a phase I pharmacokinetic study. Clin Cancer Res. 2006 Aug 01; 12(15):4645-51. Simon GR, Garrett CR, Olson SC, Langevin M, Eiseman IA, Mahany JJ, Williams CC, Lush R, Daud A, Munster P, Chiappori A, Fishman M, Bepler G, Lenehan PF, Sullivan DM. PMID: 16899614.
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    166. Melanoma. J Natl Compr Canc Netw. 2006 Aug; 4(7):666-84. Houghton AN, Coit DG, Daud A, Dilawari RA, Dimaio D, Gollob JA, Haas NB, Halpern A, Johnson TM, Kashani-Sabet M, Kraybill WG, Lange JR, Martini M, Ross MI, Samlowski WE, Sener SF, Tanabe KK, Thompson JA, Trisal V, Urist MM, Walker MJ, National Comprehensive Cancer Network. PMID: 16884669.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    167. Preoperative esophageal manometry and outcome of laparoscopic adjustable silicone gastric banding. Surg Endosc. 2006 Aug; 20(8):1242-7. Lew JI, Daud A, DiGorgi MF, Olivero-Rivera L, Davis DG, Bessler M. PMID: 16858533.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    168. Unintentional creation of reverse peristaltic alimentary limb during Roux-en-Y gastric bypass surgery. Surg Obes Relat Dis. 2006 Jul-Aug; 2(4):478-82. Schrope BA, Daud A, Bessler M. PMID: 16925386.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    169. Overall and progression-free survival in metastatic melanoma: analysis of a single-institution database. Cancer Control. 2006 Jul; 13(3):211-7. Khan MA, Andrews S, Ismail-Khan R, Munster PN, Brem S, King J, Reintgen DS, Sondak VK, Daud AI. PMID: 16885917.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    170. Anti-inflammatory, anti-nociceptive and antipyretic effects of extracts of Phrygilanthus acutifolius flowers. J Ethnopharmacol. 2006 Nov 24; 108(2):198-203. Daud A, Habib N, Riera AS. PMID: 16797151.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    171. Evaluation of toxicity following electrically mediated interleukin-12 gene delivery in a B16 mouse melanoma model. Clin Cancer Res. 2006 May 15; 12(10):3177-83. Heller L, Merkler K, Westover J, Cruz Y, Coppola D, Benson K, Daud A, Heller R. PMID: 16707618.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    172. Immunotherapy as part of a multidisciplinary approach to melanoma treatment. Front Biosci. 2006 Jan 01; 11:1-14. Riker AI, Jove R, Daud AI. PMID: 16146709.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    173. Early U.S. outcomes of laparoscopic gastric bypass versus laparoscopic adjustable silicone gastric banding for morbid obesity. Surg Endosc. 2006 Feb; 20(2):202-9. Kim TH, Daud A, Ude AO, DiGiorgi M, Olivero-Rivera L, Schrope B, Davis D, Inabnet WB, Bessler M. PMID: 16341569.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    174. Synergistic interaction between histone deacetylase and topoisomerase II inhibitors is mediated through topoisomerase IIbeta. Clin Cancer Res. 2005 Dec 01; 11(23):8467-75. Marchion DC, Bicaku E, Turner JG, Daud AI, Sullivan DM, Munster PN. PMID: 16322310.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    175. In vivo synergy between topoisomerase II and histone deacetylase inhibitors: predictive correlates. Mol Cancer Ther. 2005 Dec; 4(12):1993-2000. Marchion DC, Bicaku E, Daud AI, Sullivan DM, Munster PN. PMID: 16373714.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    176. Cutaneous melanoma: prognostic factors. Cancer Control. 2005 Oct; 12(4):223-9. Homsi J, Kashani-Sabet M, Messina JL, Daud A. PMID: 16258493.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    177. Valproic acid alters chromatin structure by regulation of chromatin modulation proteins. Cancer Res. 2005 May 01; 65(9):3815-22. Marchion DC, Bicaku E, Daud AI, Sullivan DM, Munster PN. PMID: 15867379.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    178. Phase II trial of karenitecin in patients with malignant melanoma: clinical and translational study. Clin Cancer Res. 2005 Apr 15; 11(8):3009-16. Daud A, Valkov N, Centeno B, Derderian J, Sullivan P, Munster P, Urbas P, Deconti RC, Berghorn E, Liu Z, Hausheer F, Sullivan D. PMID: 15837755.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCellsCTClinical Trials
    179. Uncommon manifestations of common malignancies: case 3. Malignant melanoma arising from a spinal nerve root. J Clin Oncol. 2004 Aug 01; 22(15):3194-5. Naing A, Messina JL, Vrionis FR, Daud AI. PMID: 15284274.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    180. Sequence-specific potentiation of topoisomerase II inhibitors by the histone deacetylase inhibitor suberoylanilide hydroxamic acid. J Cell Biochem. 2004 May 15; 92(2):223-37. Marchion DC, Bicaku E, Daud AI, Richon V, Sullivan DM, Munster PN. PMID: 15108350.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    181. Roles of activated Src and Stat3 signaling in melanoma tumor cell growth. Oncogene. 2002 Oct 10; 21(46):7001-10. Niu G, Bowman T, Huang M, Shivers S, Reintgen D, Daud A, Chang A, Kraker A, Jove R, Yu H. PMID: 12370822.
      View in: PubMed   Mentions: 143     Fields:    Translation:HumansCells
    182. A phase I trial of the novel proteasome inhibitor PS341 in advanced solid tumor malignancies. Clin Cancer Res. 2002 Aug; 8(8):2505-11. Aghajanian C, Soignet S, Dizon DS, Pien CS, Adams J, Elliott PJ, Sabbatini P, Miller V, Hensley ML, Pezzulli S, Canales C, Daud A, Spriggs DR. PMID: 12171876.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansCellsCTClinical Trials
    183. New drugs in gynecologic cancer. Curr Treat Options Oncol. 2001 Apr; 2(2):119-28. Daud A, Munster P, Munster P, Spriggs DR. PMID: 12057130.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    184. Intrahepatic stones: the UKM experience. Med J Malaysia. 2000 Dec; 55(4):473-7. Din J, Qureshi A, Daud A, Ahmad H. PMID: 11221160.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    185. Comparison of the Ca2 + currents induced by expression of three cloned alpha1 subunits, alpha1G, alpha1H and alpha1I, of low-voltage-activated T-type Ca2 + channels. Eur J Neurosci. 1999 Dec; 11(12):4171-8. Klöckner U, Lee JH, Cribbs LL, Daud A, Hescheler J, Pereverzev A, Perez-Reyes E, Schneider T. PMID: 10594642.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    186. Differential distribution of three members of a gene family encoding low voltage-activated (T-type) calcium channels. J Neurosci. 1999 Mar 15; 19(6):1895-911. Talley EM, Cribbs LL, Lee JH, Daud A, Perez-Reyes E, Bayliss DA. PMID: 10066243; PMCID: PMC6782581.
      View in: PubMed   Mentions: 325     Fields:    Translation:AnimalsCells
    187. Cloning and characterization of alpha1H from human heart, a member of the T-type Ca2+ channel gene family. Circ Res. 1998 Jul 13; 83(1):103-9. Cribbs LL, Lee JH, Yang J, Satin J, Zhang Y, Daud A, Barclay J, Williamson MP, Fox M, Rees M, Perez-Reyes E. PMID: 9670923.
      View in: PubMed   Mentions: 162     Fields:    Translation:HumansAnimalsCells
    188. Molecular characterization of a neuronal low-voltage-activated T-type calcium channel. Nature. 1998 Feb 26; 391(6670):896-900. Perez-Reyes E, Cribbs LL, Daud A, Lacerda AE, Barclay J, Williamson MP, Fox M, Rees M, Lee JH. PMID: 9495342.
      View in: PubMed   Mentions: 223     Fields:    Translation:HumansAnimalsCells
    189. Tumor suppressor gene expression during normal and pathologic myocardial growth. J Biol Chem. 1994 Sep 09; 269(36):22607-13. Kim KK, Soonpaa MH, Daud AI, Koh GY, Kim JS, Field LJ. PMID: 8077211.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    190. Characterization of angiotensin I-converting enzyme (ACE)-containing follicles in the rat ovary during the estrous cycle and effects of ACE inhibitor on ovulation. Endocrinology. 1990 Jun; 126(6):2927-35. Daud AI, Bumpus FM, Husain A. PMID: 2161740.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
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