Alessandro Didonna, PhD
|
Title(s) | Assistant Professor, Neurology |
---|
School | School of Medicine |
---|
Phone | 415-476-1335 |
---|
vCard | Download vCard |
---|
|
|
Biography University of Bari, Italy | B.Sc. | 2004 | Cell and Molecular Biology | University of Bari, Italy | M.Sc. | 2006 | Cell and Molecular Biology | International School for Advanced Studies, Italy | Ph.D. | 2010 | Functional and Structural Genomics | Northwestern University | Postdoctoral Fellow | 2011 | Neurology | University of California, San Francisco | Postdoctoral Fellow | 2013 | Neurology |
University of Bari | 2001
-
| 2006 | Graduation with honors (summa cum laude) | Italian Multiple Sclerosis Foundation (FISM) | 2015
-
| 2017 | Senior Research Fellowship | American Neurological Association | 2015 | | Travel Grant | American Society for Cell Biology | 2016 | | Travel Grant | Italian Multiple Sclerosis Foundation (FISM) | 2017 | | Young Researcher Best Poster Award | Conrad N. Hilton Foundation | 2017
-
| 2019 | Marilyn Hilton Award for Innovation in MS Research | European Molecular Biology Organization | 2017 | | Travel Grant | University of California San Francisco | 2018 | | Pilot Award for Junior Investigators in Basic and Clinical/Translational Sciences | Italian Multiple Sclerosis Foundation (FISM) | 2018
-
| 2020 | Senior Research Fellowship | Queen's University Belfast | 2018 | | Visiting Research Fellow |
Research ORNG Applications Bibliographic
-
Frederick NM, Shah PV, Didonna A, Langley MR, Kanthasamy AG, Opal P. Loss of the dystonia gene Thap1 leads to transcriptional deficits that converge on common pathogenic pathways in dystonic syndromes. Hum Mol Genet. 2018 Dec 26. PMID: 30590536.
-
Edamakanti CR, Do J, Didonna A, Martina M, Opal P. Mutant ataxin1 disrupts cerebellar development in spinocerebellar ataxia type 1. J Clin Invest. 2018 Jun 01; 128(6):2252-2265. PMID: 29533923.
-
Canto E, Isobe N, Didonna A, Hauser SL, Oksenberg JR. Aberrant STAT phosphorylation signaling in peripheral blood mononuclear cells from multiple sclerosis patients. J Neuroinflammation. 2018 Mar 07; 15(1):72. PMID: 29514694.
-
Didonna A,
Oksenberg JR.Multiple Sclerosis: Perspectives in Treatment and Pathogenesis.
Ian S. Zagon and Patricia J. McLaughlin (Editors). The Genetics of Multiple Sclerosis. 2017; 3-16.
-
Guglielmetti C, Najac C, Didonna A, Van der Linden A, Ronen SM, Chaumeil MM. Hyperpolarized 13C MR metabolic imaging can detect neuroinflammation in vivo in a multiple sclerosis murine model. Proc Natl Acad Sci U S A. 2017 08 15; 114(33):E6982-E6991. PMID: 28760957.
-
Didonna A, Opal P. Advances in Sequencing Technologies for Understanding Hereditary Ataxias: A Review. JAMA Neurol. 2016 Dec 01; 73(12):1485-1490. PMID: 27749953.
-
Didonna A, Cekanaviciute E, Oksenberg JR, Baranzini SE. Immune cell-specific transcriptional profiling highlights distinct molecular pathways controlled by Tob1 upon experimental autoimmune encephalomyelitis. Sci Rep. 2016 08 22; 6:31603. PMID: 27546286.
-
Didonna A,
Benetti F.Post-translational modifications in neurodegeneration. AIMS Biophysics. 2016; 1(3):27-49.
-
Didonna A. Preclinical Models of Multiple Sclerosis: Advantages and Limitations Towards Better Therapies. Curr Med Chem. 2016; 23(14):1442-59. PMID: 27048376.
-
Didonna A, Isobe N, Caillier SJ, Li KH, Burlingame AL, Hauser SL, Baranzini SE, Patsopoulos NA, Oksenberg JR. A non-synonymous single-nucleotide polymorphism associated with multiple sclerosis risk affects the EVI5 interactome. Hum Mol Genet. 2015 Dec 15; 24(24):7151-8. PMID: 26433934; PMCID: PMC5007634 [Available on 12/15/16].
-
Didonna A, Venturini AC, Hartman K, Vranac T, Curin Šerbec V, Legname G. Characterization of four new monoclonal antibodies against the distal N-terminal region of PrP(c). PeerJ. 2015; 3:e811. PMID: 25802800; PMCID: PMC4369333.
-
Didonna A, Oksenberg JR. Genetic determinants of risk and progression in multiple sclerosis. Clin Chim Acta. 2015 Sep 20; 449:16-22. PMID: 25661088; PMCID: PMC4524789 [Available on 09/20/16].
-
Didonna A, Opal P. The promise and perils of HDAC inhibitors in neurodegeneration. Ann Clin Transl Neurol. 2015 Jan; 2(1):79-101. PMID: 25642438; PMCID: PMC4301678.
-
Venkatraman A, Hu YS, Didonna A, Cvetanovic M, Krbanjevic A, Bilesimo P, Opal P. The histone deacetylase HDAC3 is essential for Purkinje cell function, potentially complicating the use of HDAC inhibitors in SCA1. Hum Mol Genet. 2014 Jul 15; 23(14):3733-45. PMID: 24594842; PMCID: PMC4065149.
-
Mahammad S, Murthy SN, Didonna A, Grin B, Israeli E, Perrot R, Bomont P, Julien JP, Kuczmarski E, Opal P, Goldman RD. Giant axonal neuropathy-associated gigaxonin mutations impair intermediate filament protein degradation. J Clin Invest. 2013 May; 123(5):1964-75. PMID: 23585478; PMCID: PMC3635735.
-
Didonna A. Prion protein and its role in signal transduction. Cell Mol Biol Lett. 2013 Jun; 18(2):209-30. PMID: 23479001.
-
Didonna A, Sussman J, Benetti F, Legname G. The role of Bax and caspase-3 in doppel-induced apoptosis of cerebellar granule cells. Prion. 2012 Jul 01; 6(3):309-16. PMID: 22561161; PMCID: PMC3399532.
-
Didonna A, Vaccari L, Bek A, Legname G. Infrared microspectroscopy: a multiple-screening platform for investigating single-cell biochemical perturbations upon prion infection. ACS Chem Neurosci. 2011 Mar 16; 2(3):160-74. PMID: 22778865.
-
Didonna A, Legname G. Aberrant ERK 1/2 complex activation and localization in scrapie-infected GT1-1 cells. Mol Neurodegener. 2010 Aug 09; 5:29. PMID: 20696038; PMCID: PMC2928767.
|
Concepts Derived automatically from this person's publications. _
Co-Authors People in Profiles who have published with this person. _
Similar People People who share similar concepts with this person. _
|