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Alex Pollen, PhD

TitleAssistant Professor
InstitutionUniversity of California San Francisco
DepartmentNeurology
Address35 Medical Center Way
San Francisco CA 94143
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Mostajo-Radji MA, Pollen A. Postmitotic Fate Refinement in the Subplate. Cell Stem Cell. 2018 Jul 05; 23(1):7-9. PMID: 29979992.
      View in: PubMed
    2. Kronenberg ZN, Fiddes IT, Gordon D, Murali S, Cantsilieris S, Meyerson OS, Underwood JG, Nelson BJ, Chaisson MJP, Dougherty ML, Munson KM, Hastie AR, Diekhans M, Hormozdiari F, Lorusso N, Hoekzema K, Qiu R, Clark K, Raja A, Welch AE, Sorensen M, Baker C, Fulton RS, Armstrong J, Graves-Lindsay TA, Denli AM, Hoppe ER, Hsieh P, Hill CM, Pang AWC, Lee J, Lam ET, Dutcher SK, Gage FH, Warren WC, Shendure J, Haussler D, Schneider VA, Cao H, Ventura M, Wilson RK, Paten B, Pollen A, Eichler EE. High-resolution comparative analysis of great ape genomes. Science. 2018 06 08; 360(6393). PMID: 29880660.
      View in: PubMed
    3. Fiddes IT, Lodewijk GA, Mooring M, Bosworth CM, Ewing AD, Mantalas GL, Novak AM, van den Bout A, Bishara A, Rosenkrantz JL, Lorig-Roach R, Field AR, Haeussler M, Russo L, Bhaduri A, Nowakowski TJ, Pollen A, Dougherty ML, Nuttle X, Addor MC, Zwolinski S, Katzman S, Kriegstein A, Eichler EE, Salama SR, Jacobs FMJ, Haussler D. Human-Specific NOTCH2NL Genes Affect Notch Signaling and Cortical Neurogenesis. Cell. 2018 May 31; 173(6):1356-1369.e22. PMID: 29856954.
      View in: PubMed
    4. Nowakowski TJ, Bhaduri A, Pollen A, Alvarado B, Mostajo-Radji MA, Di Lullo E, Haeussler M, Sandoval-Espinosa C, Liu SJ, Velmeshev D, Ounadjela JR, Shuga J, Wang X, Lim DA, West JA, Leyrat AA, Kent WJ, Kriegstein AR. Spatiotemporal gene expression trajectories reveal developmental hierarchies of the human cortex. Science. 2017 12 08; 358(6368):1318-1323. PMID: 29217575.
      View in: PubMed
    5. Bershteyn M, Nowakowski TJ, Pollen A, Di Lullo E, Nene A, Wynshaw-Boris A, Kriegstein AR. Human iPSC-Derived Cerebral Organoids Model Cellular Features of Lissencephaly and Reveal Prolonged Mitosis of Outer Radial Glia. Cell Stem Cell. 2017 04 06; 20(4):435-449.e4. PMID: 28111201.
      View in: PubMed
    6. Retallack H, Di Lullo E, Arias C, Knopp KA, Laurie MT, Sandoval-Espinosa C, Mancia Leon WR, Krencik R, Ullian EM, Spatazza J, Pollen A, Mandel-Brehm C, Nowakowski TJ, Kriegstein AR, DeRisi JL. Zika virus cell tropism in the developing human brain and inhibition by azithromycin. Proc Natl Acad Sci U S A. 2016 12 13; 113(50):14408-14413. PMID: 27911847.
      View in: PubMed
    7. Müller S, Liu SJ, Di Lullo E, Malatesta M, Pollen A, Nowakowski TJ, Kohanbash G, Aghi M, Kriegstein AR, Lim DA, Diaz A. Single-cell sequencing maps gene expression to mutational phylogenies in PDGF- and EGF-driven gliomas. Mol Syst Biol. 2016 Nov 25; 12(11):889. PMID: 27888226.
      View in: PubMed
    8. Pollen A, Kriegstein AR. Primate Neurons Flex Their Musclin. Neuron. 2016 Nov 23; 92(4):681-683. PMID: 27883900.
      View in: PubMed
    9. Nowakowski TJ, Pollen A, Sandoval-Espinosa C, Kriegstein AR. Transformation of the Radial Glia Scaffold Demarcates Two Stages of Human Cerebral Cortex Development. Neuron. 2016 Sep 21; 91(6):1219-1227. PMID: 27657449.
      View in: PubMed
    10. Diaz A, Liu SJ, Sandoval C, Pollen A, Nowakowski TJ, Lim DA, Kriegstein A. SCell: integrated analysis of single-cell RNA-seq data. Bioinformatics. 2016 07 15; 32(14):2219-20. PMID: 27153637; PMCID: PMC4937196 [Available on 07/15/17].
    11. Liu SJ, Nowakowski TJ, Pollen A, Lui JH, Horlbeck MA, Attenello FJ, He D, Weissman JS, Kriegstein AR, Diaz AA, Lim DA. Single-cell analysis of long non-coding RNAs in the developing human neocortex. Genome Biol. 2016 Apr 14; 17:67. PMID: 27081004; PMCID: PMC4831157.
    12. Nowakowski TJ, Pollen A, Di Lullo E, Sandoval-Espinosa C, Bershteyn M, Kriegstein AR. Expression Analysis Highlights AXL as a Candidate Zika Virus Entry Receptor in Neural Stem Cells. Cell Stem Cell. 2016 05 05; 18(5):591-6. PMID: 27038591.
      View in: PubMed
    13. Pollen A, Nowakowski TJ, Chen J, Retallack H, Sandoval-Espinosa C, Nicholas CR, Shuga J, Liu SJ, Oldham MC, Diaz A, Lim DA, Leyrat AA, West JA, Kriegstein AR. Molecular identity of human outer radial glia during cortical development. Cell. 2015 Sep 24; 163(1):55-67. PMID: 26406371; PMCID: PMC4583716.
    14. Lui JH, Nowakowski TJ, Pollen A, Javaherian A, Kriegstein AR, Oldham MC. Radial glia require PDGFD-PDGFRß signalling in human but not mouse neocortex. Nature. 2014 Nov 13; 515(7526):264-8. PMID: 25391964; PMCID: PMC4231536.
    15. Pollen A, Nowakowski TJ, Shuga J, Wang X, Leyrat AA, Lui JH, Li N, Szpankowski L, Fowler B, Chen P, Ramalingam N, Sun G, Thu M, Norris M, Lebofsky R, Toppani D, Kemp DW, Wong M, Clerkson B, Jones BN, Wu S, Knutsson L, Alvarado B, Wang J, Weaver LS, May AP, Jones RC, Unger MA, Kriegstein AR, West JA. Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex. Nat Biotechnol. 2014 Oct; 32(10):1053-8. PMID: 25086649; PMCID: PMC4191988.
    16. Molnár Z, Pollen A. How unique is the human neocortex? Development. 2014 Jan; 141(1):11-6. PMID: 24346696.
      View in: PubMed
    17. Jones FC, Grabherr MG, Chan YF, Russell P, Mauceli E, Johnson J, Swofford R, Pirun M, Zody MC, White S, Birney E, Searle S, Schmutz J, Grimwood J, Dickson MC, Myers RM, Miller CT, Summers BR, Knecht AK, Brady SD, Zhang H, Pollen A, Howes T, Amemiya C. The genomic basis of adaptive evolution in threespine sticklebacks. Nature. 2012 Apr 04; 484(7392):55-61. PMID: 22481358.
      View in: PubMed
    18. McLean CY, Reno PL, Pollen A, Bassan AI, Capellini TD, Guenther C, Indjeian VB, Lim X, Menke DB, Schaar BT, Wenger AM, Bejerano G, Kingsley DM. Human-specific loss of regulatory DNA and the evolution of human-specific traits. Nature. 2011 Mar 10; 471(7337):216-9. PMID: 21390129; PMCID: PMC3071156.
    19. Machado HE, Pollen A, Hofmann HA, Renn SC. Interspecific profiling of gene expression informed by comparative genomic hybridization: A review and a novel approach in African cichlid fishes. Integr Comp Biol. 2009 Dec; 49(6):644-59. PMID: 21665847.
      View in: PubMed
    20. Pollen A, Hofmann HA. Beyond neuroanatomy: novel approaches to studying brain evolution. Brain Behav Evol. 2008; 72(2):145-58. PMID: 18836260.
      View in: PubMed
    21. Miller CT, Beleza S, Pollen A, Schluter D, Kittles RA, Shriver MD, Kingsley DM. cis-Regulatory changes in Kit ligand expression and parallel evolution of pigmentation in sticklebacks and humans. Cell. 2007 Dec 14; 131(6):1179-89. PMID: 18083106; PMCID: PMC2900316.
    22. Cheung AF, Pollen A, Tavare A, DeProto J, Molnár Z. Comparative aspects of cortical neurogenesis in vertebrates. J Anat. 2007 Aug; 211(2):164-76. PMID: 17634059; PMCID: PMC2375772.
    23. Pollen A, Dobberfuhl AP, Scace J, Igulu MM, Renn SC, Shumway CA, Hofmann HA. Environmental complexity and social organization sculpt the brain in Lake Tanganyikan cichlid fish. Brain Behav Evol. 2007; 70(1):21-39. PMID: 17389793.
      View in: PubMed