Alexander Haddad, MD

Title(s)Resident, Neurological Surgery
SchoolSchool of Medicine
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoMD05/2021Medicine
    University of California, San FranciscoResidency06/2028Neurological Surgery
    Collapse Awards and Honors
    Zuckerberg San Francisco General Hospital and Trauma Center  - 2022Krevans Award for Excellence in Patient Care
    University of California, San Francisco  - 2022Catalyst Award
    University of California, San Francisco School of Medicine  - 2021MD with Distinction
    University of California, San Francisco School of Medicine  - 2021Steinhart Award
    University of California, San Francisco School of Medicine  - 2021Long-Term Research Dean's Prize
    UC Berkeley Big Ideas Competition  - 2017First Place, "IT for Society"
    National Institutes of Health  - 2016Postbaccalaureate Intramural Research Training Award (IRTA)
    DePaul University  - 2015summa cum laude
    DePaul University  - 2015Departmental Award for Outstanding Performance in Biochemistry
    DePaul University  - 2015Departmental Award for Outstanding Performance in Organic Chemistry
    DePaul University  - 2015Biological Sciences Department Senior Appreciation Award

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Synthetic Novel Replicating Retroviral Gene Therapy Platform for the Treatment of Glioblastoma
    UCSF CATALYST PROGRAM Mar 1, 2022 - Mar 1, 2023
    Role: Principal Investigator

    Collapse Featured Content 
    Collapse Twitter

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cardiac Complications After 3-Column Osteotomy for Adult Spinal Deformity Patients With Formal Cardiac Clearance: Identifying Key Risk Factors and Threshold Cutoffs Via Recursive Partitioning Analysis. Neurosurgery. 2022 Oct 01; 91(4):562-569. Lau D, Haddad AF, Joshi RS, Deviren V, Ames CP. PMID: 35830241.
      View in: PubMed   Mentions:    Fields:    
    2. Evacuation of a multi-loculated acute-on-chronic subdural hematoma using tandem bedside subdural evacuation port systems. Trauma Case Rep. 2022 Aug; 40:100668. Yue JK, Haddad AF, Wang AS, Caldwell DJ, Umbach G, Digiorgio AM, Tarapore PE, Huang MC, Manley GT. PMID: 35794957; PMCID: PMC9251328.
      View in: PubMed   Mentions:
    3. The Hybrid Operative Suite with Intraoperative Biplane Rotational Angiography in Pediatric Cerebrovascular Neurosurgery: Utility and Lessons Learned. Pediatr Neurosurg. 2022; 57(4):245-259. Yue JK, Chang D, Caton MT, Haddad AF, Dalle Ore CL, Wozny TA, Oh T, Wang AS, Tonetti DA, Auguste KI, Sun PP, Cooke DL, Hetts SW, Abla AA, Gupta N, Roland JL. PMID: 35508115.
      View in: PubMed   Mentions:    Fields:    
    4. In Reply: The Morbidity and Mortality of Surgery for Traumatic Brain Injury in Geriatric Patients: A Study of Over 100 000 Patient Cases. Neurosurgery. 2022 07 01; 91(1):e22-e23. Haddad AF, DiGiorgio AM, Tarapore PE. PMID: 35482333.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Pituitary adenoma in the elderly: surgical outcomes and treatment trends in the United States. J Neurosurg. 2022 Apr 29; 1-12. Chalif EJ, Morshed RA, Young JS, Haddad AF, Jain S, Aghi MK. PMID: 35535847.
      View in: PubMed   Mentions:    Fields:    
    6. FLAIRectomy: Resecting beyond the Contrast Margin for Glioblastoma. Brain Sci. 2022 Apr 25; 12(5). Haddad AF, Young JS, Morshed RA, Berger MS. PMID: 35624931; PMCID: PMC9139350.
      View in: PubMed   Mentions:
    7. Resistance to immune checkpoint blockade: Mechanisms, counter-acting approaches, and future directions. Semin Cancer Biol. 2022 Mar 09. Haddad AF, Young JS, Gill S, Aghi MK. PMID: 35276342; PMCID: PMC9458771.
      View in: PubMed   Mentions: 1     Fields:    
    8. Pearls and Pitfalls of Awake Spine Surgery: A Simplified Patient-Selection Algorithm. World Neurosurg. 2022 May; 161:154-155. Letchuman V, Agarwal N, Mummaneni VP, Wang MY, Shabani S, Patel A, Rivera J, Haddad A, Le V, Chang JM, Chou D, Gandhi S, Mummaneni PV. PMID: 35217225.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. The immunology of low-grade gliomas. Neurosurg Focus. 2022 02; 52(2):E2. Haddad AF, Young JS, Oh JY, Okada H, Aghi MK. PMID: 35104791; PMCID: PMC9283531.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Incidence and Risk Factors of Mechanical Complications After Posterior-Based Osteotomies for Correction of Moderate to Severe Adult Cervical Deformity: 1-Year and 2-Year Follow-up. Neurosurgery. 2022 02 01; 90(2):207-214. Lau D, Joshi RS, Haddad AF, Deviren V, Ames CP. PMID: 34995272.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Identifying risk factors for postoperative diabetes insipidus in more than 2500 patients undergoing transsphenoidal surgery: a single-institution experience. J Neurosurg. 2022 Jan 28; 1-11. Joshi RS, Pereira MP, Osorio RC, Oh T, Haddad AF, Pereira KM, Donohue KC, Peeran Z, Sudhir S, Jain S, Beniwal A, Chandra A, Han SJ, Rolston JD, Theodosopoulos PV, Kunwar S, Blevins LS, Aghi MK. PMID: 35090129.
      View in: PubMed   Mentions:    Fields:    
    12. Do social determinants of health impact access to neurosurgical care in the United States? A workforce perspective. J Neurosurg. 2022 Jan 14; 1-10. Perera S, Hervey-Jumper SL, Mummaneni PV, Barthélemy EJ, Haddad AF, Marotta DA, Burke JF, Chan AK, Manley GT, Tarapore PE, Huang MC, Dhall SS, Chou D, Orrico KO, DiGiorgio AM. PMID: 35472666.
      View in: PubMed   Mentions:    Fields:    
    13. The effect of levetiracetam treatment on survival in patients with glioblastoma: a systematic review and meta-analysis. J Neurooncol. 2022 Jan; 156(2):257-267. Chen JS, Clarke R, Haddad AF, Wang EJ, Lacroix M, Sarkar IN, Zand R, Chen ES, Toms SA. PMID: 34982371.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Reducing complication rates for repeat craniotomies in glioma patients: a single-surgeon experience and comparison with the literature. Acta Neurochir (Wien). 2022 02; 164(2):405-417. Morshed RA, Young JS, Gogos AJ, Haddad AF, McMahon JT, Molinaro AM, Sudhakar V, Al-Adli N, Hervey-Jumper SL, Berger MS. PMID: 34970702; PMCID: PMC8854329.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. Pseudo-insular glioma syndrome: illustrative cases. J Neurosurg Case Lessons. 2021 Dec 27; 2(26):CASE21481. Haddad AF, Young JS, Morshed RA, Josephson SA, Cha S, Berger MS. PMID: 35854917; PMCID: PMC9281470.
      View in: PubMed   Mentions:
    16. Immunotherapy Resistance in Glioblastoma. Front Genet. 2021; 12:750675. Wang EJ, Chen JS, Jain S, Morshed RA, Haddad AF, Gill S, Beniwal AS, Aghi MK. PMID: 34976006; PMCID: PMC8718605.
      View in: PubMed   Mentions:
    17. Management of Malpositioned Cervical Interfacet Spacers: An Institutional Case Series. Cureus. 2021 Dec; 13(12):e20450. Garcia JH, Haddad AF, Patel A, Safaee MM, Pennicooke B, Mummaneni PV, Clark AJ. PMID: 35070522; PMCID: PMC8763025.
      View in: PubMed   Mentions:
    18. Awake spinal surgery: simplifying the learning curve with a patient selection algorithm. Neurosurg Focus. 2021 12; 51(6):E2. Letchuman V, Agarwal N, Mummaneni VP, Wang MY, Shabani S, Patel A, Rivera J, Haddad AF, Le V, Chang JM, Chou D, Gandhi S, Mummaneni PV. PMID: 34852318.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. The Morbidity and Mortality of Surgery for Traumatic Brain Injury in Geriatric Patients: A Study of Over 100 000 Patient Cases. Neurosurgery. 2021 11 18; 89(6):1062-1070. Haddad AF, DiGiorgio AM, Lee YM, Lee AT, Burke JF, Huang MC, Dhall SS, Manley GT, Tarapore PE. PMID: 34624082.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Incidence of Chronic Periscapular Pain After Adult Thoracolumbar Deformity Correction and Impact on Outcomes. Neurospine. 2021 Sep; 18(3):515-523. Haddad AF, Scheer JK, Fury MT, Smith JS, Deviren V, Ames CP. PMID: 34610684; PMCID: PMC8497237.
      View in: PubMed   Mentions:
    21. Multiple-rod constructs and use of bone morphogenetic protein-2 in relation to lower rod fracture rates in 141 patients with adult spinal deformity who underwent lumbar pedicle subtraction osteotomy. J Neurosurg Spine. 2021 Sep 24; 1-11. Lyu Q, Lau D, Haddad AF, Deviren V, Ames CP. PMID: 34560633.
      View in: PubMed   Mentions:    Fields:    
    22. Lymphocele after anterior lumbar interbody fusion: a review of 1322 patients. J Neurosurg Spine. 2021 Aug 20; 35(6):722-728. Scheer JK, Haddad AF, Chan AK, Eichler CM, Tay B, Burch S, Chou D, Ames CP, Mummaneni PV. PMID: 34416719.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. Reduced proximal junctional failure with ligament augmentation in adult spinal deformity: a series of 242 cases with a minimum 1-year follow-up. J Neurosurg Spine. 2021 Aug 20; 35(6):752-760. Safaee MM, Haddad AF, Fury M, Maloney PR, Scheer JK, Lau D, Deviren V, Ames CP. PMID: 34416735.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Mouse models of glioblastoma for the evaluation of novel therapeutic strategies. Neurooncol Adv. 2021 Jan-Dec; 3(1):vdab100. Haddad AF, Young JS, Amara D, Berger MS, Raleigh DR, Aghi MK, Butowski NA. PMID: 34466804; PMCID: PMC8403483.
      View in: PubMed   Mentions: 6  
    25. The Natural History of Spinal Cord Injury. Neurosurg Clin N Am. 2021 Jul; 32(3):315-321. Haddad AF, Burke JF, Dhall SS. PMID: 34053719.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Telemedicine in Neurosurgery: Standardizing the Spinal Physical Examination Using A Modified Delphi Method. Neurospine. 2021 Jun; 18(2):292-302. Haddad AF, Burke JF, Mummaneni PV, Chan AK, Safaee MM, Knightly JJ, Mayer RR, Pennicooke BH, Digiorgio AM, Weinstein PR, Clark AJ, Chou D, Dhall SS. PMID: 34218612; PMCID: PMC8255762.
      View in: PubMed   Mentions:
    27. An analysis of tumor-related potential spinal column instability (Spine Instability Neoplastic Scores 7-12) eventually requiring surgery with a 1-year follow-up. Neurosurg Focus. 2021 05; 50(5):E6. Vargas E, Lockney DT, Mummaneni PV, Haddad AF, Rivera J, Tan X, Jamieson A, Mahmoudieh Y, Berven S, Braunstein SE, Chou D. PMID: 33932936.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    28. Plurihormonal PIT-1-Positive Pituitary Adenomas: A Systematic Review and Single-Center Series. World Neurosurg. 2021 07; 151:e185-e191. Andrews JP, Joshi RS, Pereira MP, Oh T, Haddad AF, Pereira KM, Osorio RC, Donohue KC, Peeran Z, Sudhir S, Jain S, Beniwal A, Chopra AS, Sandhu NS, Tihan T, Blevins L, Aghi MK. PMID: 33862299.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    29. Pathologic Findings Associated With a Case of Acute Flaccid Myelitis. J Neuropathol Exp Neurol. 2021 Apr 16; 80(5):484-487. Haddad AF, Hofmann JW, Oh T, Jacques L, Yu G, Chiu C, Nolan A, Strober J, Gupta N. PMID: 33870421.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    30. Multilevel Pedicle Subtraction Osteotomy for Correction of Severe Rigid Adult Spinal Deformities: A Case Series, Indications, Considerations, and Literature Review. Oper Neurosurg (Hagerstown). 2021 03 15; 20(4):343-354. Lau D, Haddad AF, Fury MT, Deviren V, Ames CP. PMID: 33377144.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    31. Using viral vectors to deliver local immunotherapy to glioblastoma. Neurosurg Focus. 2021 02; 50(2):E4. Haddad AF, Young JS, Aghi MK. PMID: 33524947; PMCID: PMC8011938.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    32. Preoperative Applications of Navigated Transcranial Magnetic Stimulation. Front Neurol. 2020; 11:628903. Haddad AF, Young JS, Berger MS, Tarapore PE. PMID: 33551983; PMCID: PMC7862711.
      View in: PubMed   Mentions: 5  
    33. Anterior Lumbar Interbody Fusion With Cage Retrieval for the Treatment of Pseudarthrosis After Transforaminal Lumbar Interbody Fusion: A Single-Institution Case Series. Oper Neurosurg (Hagerstown). 2021 01 13; 20(2):164-173. Safaee MM, Tenorio A, Haddad AF, Wu B, Hu SS, Tay B, Burch S, Berven SH, Deviren V, Dhall SS, Chou D, Mummaneni PV, Eichler CM, Ames CP, Clark AJ. PMID: 33035339.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    34. Immunologic aspects of viral therapy for glioblastoma and implications for interactions with immunotherapies. J Neurooncol. 2021 Mar; 152(1):1-13. Haddad AF, Young JS, Mummaneni NV, Kasahara N, Aghi MK. PMID: 33389564; PMCID: PMC8011939.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    35. Navigated TMS in the ICU: Introducing Motor Mapping to the Critical Care Setting. Brain Sci. 2020 Dec 18; 10(12). Schramm S, Haddad AF, Chyall L, Krieg SM, Sollmann N, Tarapore PE. PMID: 33352857; PMCID: PMC7765929.
      View in: PubMed   Mentions: 2  
    36. Risk factors for determining length of intensive care unit and hospital stays following correction of cervical deformity: evaluation of early severe adverse events. J Neurosurg Spine. 2020 Oct 23; 1-12. Joshi RS, Lau D, Haddad AF, Deviren V, Ames CP. PMID: 33096532.
      View in: PubMed   Mentions: 1     Fields:    
    37. Higher cytolytic score correlates with an immunosuppressive tumor microenvironment and reduced survival in glioblastoma. Sci Rep. 2020 10 16; 10(1):17580. Haddad AF, Chen JS, Oh T, Pereira MP, Joshi RS, Aghi MK. PMID: 33067480; PMCID: PMC7567862.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    38. Clinical characteristics and outcomes in elderly patients undergoing transsphenoidal surgery for nonfunctioning pituitary adenoma. Neurosurg Focus. 2020 10; 49(4):E19. Pereira MP, Oh T, Joshi RS, Haddad AF, Pereira KM, Osorio RC, Donohue KC, Peeran Z, Sudhir S, Jain S, Beniwal A, Gurrola J, El-Sayed IH, Blevins LS, Theodosopoulos PV, Kunwar S, Aghi MK. PMID: 33002877.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    39. The Effect of Systemic Tranexamic Acid on Hypercoagulable Complications and Perioperative Outcomes Following Three-Column Osteotomy for Adult Spinal Deformity. Global Spine J. 2022 Apr; 12(3):423-431. Haddad AF, Ames CP, Safaee M, Deviren V, Lau D. PMID: 32969252; PMCID: PMC9121167.
      View in: PubMed   Mentions:
    40. WHO Grade I Meningioma Recurrence: Identifying High Risk Patients Using Histopathological Features and the MIB-1 Index. Front Oncol. 2020; 10:1522. Haddad AF, Young JS, Kanungo I, Sudhir S, Chen JS, Raleigh DR, Magill ST, McDermott MW, Aghi MK. PMID: 32983999; PMCID: PMC7483477.
      View in: PubMed   Mentions: 11  
    41. Asymmetrical pedicle subtraction osteotomy for correction of concurrent sagittal-coronal imbalance in adult spinal deformity: a comparative analysis. J Neurosurg Spine. 2020 Aug 07; 1-8. Lau D, Haddad AF, Deviren V, Ames CP. PMID: 32764181.
      View in: PubMed   Mentions: 2     Fields:    
    42. Factors affecting approach selection for minimally invasive versus open surgery in the treatment of adult spinal deformity: analysis of a prospective, nonrandomized multicenter study. J Neurosurg Spine. 2020 Jun 19; 1-6. Park P, Than KD, Mummaneni PV, Nunley PD, Eastlack RK, Uribe JS, Wang MY, Le V, Fessler RG, Okonkwo DO, Kanter AS, Anand N, Chou D, Fu KG, Haddad AF, Shaffrey CI, Mundis GM, International Spine Study Group. PMID: 32559745.
      View in: PubMed   Mentions: 1     Fields:    
    43. Complication profile associated with S1 pedicle subtraction osteotomy compared with 3-column osteotomies at other thoracolumbar levels for adult spinal deformity: series of 405 patients with 9 S1 osteotomies. J Neurosurg Spine. 2020 Jun 19; 1-11. Lau D, Haddad AF, Deviren V, Ames CP. PMID: 32559748.
      View in: PubMed   Mentions:    Fields:    
    44. Clinical characteristics and outcomes of null-cell versus silent gonadotroph adenomas in a series of 1166 pituitary adenomas from a single institution. Neurosurg Focus. 2020 06; 48(6):E13. Haddad AF, Young JS, Oh T, Pereira MP, Joshi RS, Pereira KM, Osorio RC, Donohue KC, Peeran Z, Sudhir S, Jain S, Beniwal A, Chopra AS, Sandhu NS, Theodosopoulos PV, Kunwar S, El-Sayed IH, Gurrola J, Blevins LS, Aghi MK. PMID: 32480370.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    45. Targeting mitochondrial and cytosolic substrates of TRIT1 isopentenyltransferase: Specificity determinants and tRNA-i6A37 profiles. PLoS Genet. 2020 04; 16(4):e1008330. Khalique A, Mattijssen S, Haddad AF, Chaudhry S, Maraia RJ. PMID: 32324744; PMCID: PMC7200024.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    46. Artificial Intelligence for Adult Spinal Deformity. Neurospine. 2019 Dec; 16(4):686-694. Joshi RS, Haddad AF, Lau D, Ames CP. PMID: 31905457; PMCID: PMC6944987.
      View in: PubMed   Mentions: 16  
    47. A Reduced Exogenous Steroid Taper for Postoperative Brain Tumor Patients-A Case-Control Study. World Neurosurg. 2019 05; 125:e44-e47. Breshears JD, Haddad AF, Viner J, Rau J, Sankaran S, McDermott MW. PMID: 30639502.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    48. Using proximity biotinylation to detect herpesvirus entry glycoprotein interactions: Limitations for integral membrane glycoproteins. J Virol Methods. 2015 Sep 01; 221:81-9. Lajko M, Haddad AF, Robinson CA, Connolly SA. PMID: 25958131; PMCID: PMC4469388.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
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