Alexander Kintzer, PhD

TitlePostdoctoral Scholar
SchoolUCSF School of Medicine
DepartmentBiochemistry and Biophysics
Address600 16th St
San Francisco CA 94158
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Kintzer A, Stroud RM. Structure, inhibition and regulation of two-pore channel TPC1 from Arabidopsis thaliana. Nature. 2016 Mar 10; 531(7593):258-62. PMID: 26961658; PMCID: PMC4863712.
    2. Kintzer A, Tang II, Schawel AK, Brown MJ, Krantz BA. Anthrax toxin protective antigen integrates poly-?-D-glutamate and pH signals to sense the optimal environment for channel formation. Proc Natl Acad Sci U S A. 2012 Nov 06; 109(45):18378-83. PMID: 23100533; PMCID: PMC3494962.
    3. von Moltke J, Trinidad NJ, Moayeri M, Kintzer A, Wang SB, van Rooijen N, Brown CR, Krantz BA, Leppla SH, Gronert K, Vance RE. Rapid induction of inflammatory lipid mediators by the inflammasome in vivo. Nature. 2012 Oct 04; 490(7418):107-11. PMID: 22902502; PMCID: PMC3465483.
    4. Sterling HJ, Kintzer A, Feld GK, Cassou CA, Krantz BA, Williams ER. Supercharging protein complexes from aqueous solution disrupts their native conformations. J Am Soc Mass Spectrom. 2012 Feb; 23(2):191-200. PMID: 22161509; PMCID: PMC3265691.
    5. Feld GK, Kintzer A, Tang II, Thoren KL, Krantz BA. Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen. J Mol Biol. 2012 Jan 06; 415(1):159-74. PMID: 22063095; PMCID: PMC3249527.
    6. Kintzer A, Sterling HJ, Tang II, Williams ER, Krantz BA. Anthrax toxin receptor drives protective antigen oligomerization and stabilizes the heptameric and octameric oligomer by a similar mechanism. PLoS One. 2010 Nov 08; 5(11):e13888. PMID: 21079738; PMCID: PMC2975657.
    7. Feld GK, Thoren KL, Kintzer A, Sterling HJ, Tang II, Greenberg SG, Williams ER, Krantz BA. Structural basis for the unfolding of anthrax lethal factor by protective antigen oligomers. Nat Struct Mol Biol. 2010 Nov; 17(11):1383-90. PMID: 21037566; PMCID: PMC3133606.
    8. Sterling HJ, Daly MP, Feld GK, Thoren KL, Kintzer A, Krantz BA, Williams ER. Effects of supercharging reagents on noncovalent complex structure in electrospray ionization from aqueous solutions. J Am Soc Mass Spectrom. 2010 Oct; 21(10):1762-74. PMID: 20673639; PMCID: PMC3141049.
    9. Kintzer A, Sterling HJ, Tang II, Abdul-Gader A, Miles AJ, Wallace BA, Williams ER, Krantz BA. Role of the protective antigen octamer in the molecular mechanism of anthrax lethal toxin stabilization in plasma. J Mol Biol. 2010 Jun 25; 399(5):741-58. PMID: 20433851; PMCID: PMC2892534.
    10. Kintzer A, Thoren KL, Sterling HJ, Dong KC, Feld GK, Tang II, Zhang TT, Williams ER, Berger JM, Krantz BA. The protective antigen component of anthrax toxin forms functional octameric complexes. J Mol Biol. 2009 Sep 25; 392(3):614-29. PMID: 19627991; PMCID: PMC2742380.
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