Alexander Von Appen, PhD

TitlePostdoctoral Scholar
InstitutionUniversity of California San Francisco
DepartmentBiochemistry and Biophysics
Address600 16th St
San Francisco CA 94158
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    1. Teimer R, Kosinski J, von Appen A, Beck M, Hurt E. A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex. Nat Commun. 2017 10 24; 8(1):1107. PMID: 29062044.
      View in: PubMed
    2. Gu M, LaJoie D, Chen OS, von Appen A, Ladinsky MS, Redd MJ, Nikolova L, Bjorkman PJ, Sundquist WI, Ullman KS, Frost A. LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells. Proc Natl Acad Sci U S A. 2017 03 14; 114(11):E2166-E2175. PMID: 28242692.
      View in: PubMed
    3. Hauke S, von Appen A, Quidwai T, Ries J, Wombacher R. Specific protein labeling with caged fluorophores for dual-color imaging and super-resolution microscopy in living cells. Chem Sci. 2017 Jan 01; 8(1):559-566. PMID: 28451202.
      View in: PubMed
    4. Kosinski J, Mosalaganti S, von Appen A, Teimer R, DiGuilio AL, Wan W, Bui KH, Hagen WJ, Briggs JA, Glavy JS, Hurt E, Beck M. Molecular architecture of the inner ring scaffold of the human nuclear pore complex. Science. 2016 Apr 15; 352(6283):363-5. PMID: 27081072.
      View in: PubMed
    5. von Appen A, Beck M. Structure Determination of the Nuclear Pore Complex with Three-Dimensional Cryo electron Microscopy. J Mol Biol. 2016 05 22; 428(10 Pt A):2001-10. PMID: 26791760; PMCID: PMC4898182.
    6. von Appen A, Kosinski J, Sparks L, Ori A, DiGuilio AL, Vollmer B, Mackmull MT, Banterle N, Parca L, Kastritis P, Buczak K, Mosalaganti S, Hagen W, Andres-Pons A, Lemke EA, Bork P, Antonin W, Glavy JS, Bui KH, Beck M. In situ structural analysis of the human nuclear pore complex. Nature. 2015 Oct 01; 526(7571):140-143. PMID: 26416747; PMCID: PMC4886846.
    7. Male G, von Appen A, Glatt S, Taylor NM, Cristovao M, Groetsch H, Beck M, Müller CW. Architecture of TFIIIC and its role in RNA polymerase III pre-initiation complex assembly. Nat Commun. 2015 Jun 10; 6:7387. PMID: 26060179; PMCID: PMC4490372.
    8. Kosinski J, von Appen A, Ori A, Karius K, Müller CW, Beck M. Xlink Analyzer: software for analysis and visualization of cross-linking data in the context of three-dimensional structures. J Struct Biol. 2015 Mar; 189(3):177-83. PMID: 25661704; PMCID: PMC4359615.
    9. Gaik M, Flemming D, von Appen A, Kastritis P, Mücke N, Fischer J, Stelter P, Ori A, Bui KH, Baßler J, Barbar E, Beck M, Hurt E. Structural basis for assembly and function of the Nup82 complex in the nuclear pore scaffold. J Cell Biol. 2015 Feb 02; 208(3):283-97. PMID: 25646085; PMCID: PMC4315244.
    10. Bui KH, von Appen A, DiGuilio AL, Ori A, Sparks L, Mackmull MT, Bock T, Hagen W, Andrés-Pons A, Glavy JS, Beck M. Integrated structural analysis of the human nuclear pore complex scaffold. Cell. 2013 Dec 05; 155(6):1233-43. PMID: 24315095.
      View in: PubMed
    11. Thierbach K, von Appen A, Thoms M, Beck M, Flemming D, Hurt E. Protein interfaces of the conserved Nup84 complex from Chaetomium thermophilum shown by crosslinking mass spectrometry and electron microscopy. Structure. 2013 Sep 03; 21(9):1672-82. PMID: 23954503.
      View in: PubMed
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