Alison Huang, MD

TitleAssociate Professor
InstitutionUniversity of California San Francisco
Address1545 Divisadero Street
San Francisco CA 94115
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoM.A.S. in Clinical Research2008 Graduate Division (Advance Training in Clinical Research)
    San Francisco Veterans Affairs Medical Center2007Ambulatory care research
    University of California, San Francisco Residency 2005Internal Medicine- Primary Care, School of Medicine
    University of California, San FranciscoM.D.2002 Medicine

    Collapse Overview 
    Collapse Overview
    Dr. Alison Huang is an internal medicine physician and a clinical researcher at the University of California San Francisco, where she conducts epidemiologic and interventional research to advance scientific understanding and improve clinical management of menopause- and aging-related health conditions in women. Among other health issues common to older women, her research program focuses on two widely prevalent but relatively understudied manifestations of menopause and aging: 1) genitourinary dysfunction, including conditions such as urinary incontinence, overactive bladder, urogenital atrophy, and sexual dysfunction; and 2) menopausal symptoms, including vasomotor symptoms such as hot flashes and nightsweats. She leads a multidisciplinary team of researchers in aging/geriatrics, urology, gynecology, and general medicine in promoting understanding of the effect of aging on health and functioning in women and developing more effective strategies to prevent and treat health conditions that lie at the interface of geriatrics and women’s health. She also teaches clinical research design in graduate courses offered by the UCSF Department of Epidemiology & Biostatistics and on-line courses offered by the UCSF Clinical & Translational Science Institute's On-Line Education department, and co-directs research training programs for residents, post-doctoral fellows, and junior faculty researchers.

    Collapse Research 
    Collapse Research Activities and Funding
    Enhancing Resident Investigation and Career Advancement in Cardiovascular and Pulmonary Science
    NIH/NHLBI R38HL143581Jul 1, 2018 - Jun 30, 2022
    Role: Principal Investigator
    Nocturnal overactive bladder and sleep disruption in middle-aged and older women
    NIH/NIA R03AG056752Aug 1, 2017 - May 31, 2019
    Role: Principal Investigator
    UCSF-Kaiser Urological Epidemiology Research Career Development Program
    NIH/NIDDK K12DK111028Sep 1, 2016 - Aug 31, 2021
    Role: Principal Investigator
    Transdermal Nitroglycerin Therapy for Menopausal Hot Flashes
    NIH/NIA R01AG050588Apr 15, 2016 - Mar 31, 2020
    Role: Principal Investigator
    Yoga to Enhance Behavioral Self-Management of Urinary Incontinence in Women
    NIH/NCCIH R34AT008028Sep 1, 2014 - Jun 30, 2018
    Role: Principal Investigator
    A Behavioral Slow-Breathing Exercise Program for Female Overactive Bladder
    NIH/NIA R01AG047894Apr 15, 2014 - Mar 31, 2019
    Role: Principal Investigator
    A Multidimensional Approach to Urogenital Aging in Older Women
    NIH/NIA K23AG038335Sep 1, 2011 - Dec 31, 2014
    Role: Principal Investigator
    Slow-Paced Respiration for Treatment of Menopausal Hot Flashes
    NIH/NCCIH R01AT005491Jul 15, 2011 - Mar 31, 2015
    Role: Co-Principal Investigator 2011-2013, Principal Investigator 2014-2015
    The Impact of Vaginal Atrophy Symptoms on Quality of Life in Postmenopausal Women
    NIH/NIA R03AG035207Sep 30, 2010 - Aug 31, 2014
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Featured Publications
    Collapse In The News
    Collapse Faculty Mentoring

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Fu P, Gibson CJ, Mendes WB, Schembri M, Huang A. Anxiety, depressive symptoms, and cardiac autonomic function in perimenopausal and postmenopausal women with hot flashes: a brief report. Menopause. 2018 Jun 18. PMID: 29916944.
      View in: PubMed
    2. Yang E, Lisha NE, Walter L, Obedin-Maliver J, Huang A. Urinary Incontinence in a National Cohort of Older Women: Implications for Caregiving and Care Dependence. J Womens Health (Larchmt). 2018 Jun 14. PMID: 29902123.
      View in: PubMed
    3. Huang A, Grady D. Rethinking the Approach to Managing Postmenopausal Vulvovaginal Symptoms. JAMA Intern Med. 2018 Mar 19. PMID: 29554180.
      View in: PubMed
    4. Winkelman WD, Warsi A, Huang A, Schembri M, Rogers RG, Richter HE, Myers DL, Kraus SR, Johnson KC, Hess R, Gregory T, Bradley CS, Arya LA, Brown JS, Stone KL, Subak LL. Sleep Quality and Daytime Sleepiness Among Women With Urgency Predominant Urinary Incontinence. Female Pelvic Med Reconstr Surg. 2018 Mar/Apr; 24(2):76-81. PMID: 29300259.
      View in: PubMed
    5. Warsi QA, Huang A, Hess R, Arya LA, Richter HE, Bradley CS, Rogers RG, Myers DL, Johnson KC, Winkelman WD, Gregory WT, Kraus SR, Schembri M, Brown JS, Stone KL, Subak LL. Association of Pharmacologic Treatment of Urgency Urinary Incontinence With Sleep Quality and Daytime Sleepiness. Obstet Gynecol. 2018 Feb; 131(2):204-211. PMID: 29324595.
      View in: PubMed
    6. Huang A, Rowen TS, Abercrombie P, Subak LL, Schembri M, Plaut T, Chao MT. Development and Feasibility of a Group-Based Therapeutic Yoga Program for Women with Chronic Pelvic Pain. Pain Med. 2017 Oct 01; 18(10):1864-1872. PMID: 28419385.
      View in: PubMed
    7. Fung CH, Vaughan CP, Markland AD, Huang A, Mitchell MN, Bliwise DL, Ancoli-Israel S, Redline S, Alessi CA, Stone K. Nocturia is Associated with Poor Sleep Quality Among Older Women in the Study of Osteoporotic Fractures. J Am Geriatr Soc. 2017 Nov; 65(11):2502-2509. PMID: 28914959.
      View in: PubMed
    8. Gibson CJ, Mendes WB, Schembri M, Grady D, Huang A. Cardiac autonomic function and hot flashes among perimenopausal and postmenopausal women. Menopause. 2017 Jul; 24(7):756-761. PMID: 28169914.
      View in: PubMed
    9. Munaganuru N, Van Den Eeden SK, Creasman J, Subak LL, Strano-Paul L, Huang A. Urine leakage during sexual activity among ethnically diverse, community-dwelling middle-aged and older women. Am J Obstet Gynecol. 2017 10; 217(4):439.e1-439.e8. PMID: 28602772.
      View in: PubMed
    10. Winkelman WD, Huang A, Schembri M, Rogers RG, Richter H, Myers DL, Kraus SR, Johnson KC, Hess R, Gregory T, Bradley CS, Arya L, Brown JS, Subak LL. Modifiers of Response to Treatment With Fesoterodine for Urgency-Predominant Urinary Incontinence in a Randomized Controlled Trial. Female Pelvic Med Reconstr Surg. 2017 Mar/Apr; 23(2):151-156. PMID: 28118174.
      View in: PubMed
    11. Suskind AM, Cawthon PM, Nakagawa S, Subak LL, Reinders I, Satterfield S, Cummings S, Cauley JA, Harris T, Huang A. Urinary Incontinence in Older Women: The Role of Body Composition and Muscle Strength: From the Health, Aging, and Body Composition Study. J Am Geriatr Soc. 2017 Jan; 65(1):42-50. PMID: 27918084.
      View in: PubMed
    12. Vaughan CP, Fung CH, Huang A, Johnson TM, Markland AD. Differences in the Association of Nocturia and Functional Outcomes of Sleep by Age and Gender: A Cross-sectional, Population-based Study. Clin Ther. 2016 Nov; 38(11):2386-2393.e1. PMID: 27751673.
      View in: PubMed
    13. Steffen KJ, King WC, White GE, Subak LL, Mitchell JE, Courcoulas AP, Flum DR, Strain G, Sarwer DB, Kolotkin RL, Pories W, Huang A. Sexual functioning of men and women with severe obesity before bariatric surgery. Surg Obes Relat Dis. 2017 Feb; 13(2):334-343. PMID: 27986585.
      View in: PubMed
    14. Huang A, Cummings SR, Schembri M, Vittinghoff E, Ganz P, Grady D. Continuous transdermal nitroglycerin therapy for menopausal hot flashes: a single-arm, dose-escalation trial. Menopause. 2016 Mar; 23(3):330-4. PMID: 26263283; PMCID: PMC4746109 [Available on 03/01/17].
    15. Jones HJ, Huang A, Subak LL, Brown JS, Lee KA. Bladder Symptoms in the Early Menopausal Transition. J Womens Health (Larchmt). 2016 05; 25(5):457-63. PMID: 26741199.
      View in: PubMed
    16. Hunter MM, Nakagawa S, Van Den Eeden SK, Kuppermann M, Huang A. Predictors of impact of vaginal symptoms in postmenopausal women. Menopause. 2016 Jan; 23(1):40-6. PMID: 26173074; PMCID: PMC4684983 [Available on 01/01/17].
    17. Duralde ER, Walter LC, Van Den Eeden SK, Nakagawa S, Subak LL, Brown JS, Thom DH, Huang A. Bridging the gap: determinants of undiagnosed or untreated urinary incontinence in women. Am J Obstet Gynecol. 2016 Feb; 214(2):266.e1-266.e9. PMID: 26348382; PMCID: PMC4830485 [Available on 02/01/17].
    18. Subak LL, King WC, Belle SH, Chen JY, Courcoulas AP, Ebel FE, Flum DR, Khandelwal S, Pender JR, Pierson SK, Pories WJ, Steffen KJ, Strain GW, Wolfe BM, Huang A. Urinary Incontinence Before and After Bariatric Surgery. JAMA Intern Med. 2015 Aug; 175(8):1378-87. PMID: 26098620; PMCID: PMC4529061.
    19. Huang A, Phillips S, Schembri M, Vittinghoff E, Grady D. Device-guided slow-paced respiration for menopausal hot flushes: a randomized controlled trial. Obstet Gynecol. 2015 May; 125(5):1130-8. PMID: 25932840; PMCID: PMC4418033.
    20. Huang A, Gregorich SE, Kuppermann M, Nakagawa S, Van Den Eeden SK, Brown JS, Richter HE, Walter LC, Thom D, Stewart AL. Day-to-Day Impact of Vaginal Aging questionnaire: a multidimensional measure of the impact of vaginal symptoms on functioning and well-being in postmenopausal women. Menopause. 2015 Feb; 22(2):144-54. PMID: 24983271; PMCID: PMC4280352.
    21. Hsu A, Nakagawa S, Walter LC, Van Den Eeden SK, Brown JS, Thom DH, Lee SJ, Huang A. The burden of nocturia among middle-aged and older women. Obstet Gynecol. 2015 Jan; 125(1):35-43. PMID: 25560101; PMCID: PMC4286307.
    22. Hsu A, Conell-Price J, Stijacic Cenzer I, Eng C, Huang A, Rice-Trumble K, Lee SJ. Predictors of urinary incontinence in community-dwelling frail older adults with diabetes mellitus in a cross-sectional study. BMC Geriatr. 2014 Dec 16; 14:137. PMID: 25514968; PMCID: PMC4274753.
    23. Appa AA, Creasman J, Brown JS, Van Den Eeden SK, Thom DH, Subak LL, Huang A. The impact of multimorbidity on sexual function in middle-aged and older women: beyond the single disease perspective. J Sex Med. 2014 Nov; 11(11):2744-55. PMID: 25146458.
      View in: PubMed
    24. Huang A, Jenny HE, Chesney MA, Schembri M, Subak LL. A group-based yoga therapy intervention for urinary incontinence in women: a pilot randomized trial. Female Pelvic Med Reconstr Surg. 2014 May-Jun; 20(3):147-54. PMID: 24763156; PMCID: PMC4310548.
    25. Huang A, Subak LL. What constitutes an adequate evaluation of device-guided breathing? JAMA Intern Med. 2014 Apr; 174(4):637. PMID: 24711181.
      View in: PubMed
    26. Fehniger JE, Brown JS, Creasman JM, Van Den Eeden SK, Thom DH, Subak LL, Huang A. Childbirth and female sexual function later in life. Obstet Gynecol. 2013 Nov; 122(5):988-97. PMID: 24104776; PMCID: PMC3813451.
    27. Farhat GN, Parimi N, Chlebowski RT, Manson JE, Anderson G, Huang A, Vittinghoff E, Lee JS, Lacroix AZ, Cauley JA, Jackson R, Grady D, Lane DS, Phillips L, Simon MS, Cummings SR. Sex hormone levels and risk of breast cancer with estrogen plus progestin. J Natl Cancer Inst. 2013 Oct 02; 105(19):1496-503. PMID: 24041978; PMCID: PMC3787910.
    28. Huang A. Nonsurgical treatments for urinary incontinence in women: summary of primary findings and conclusions. JAMA Intern Med. 2013 Aug 12; 173(15):1463-4. PMID: 23817490.
      View in: PubMed
    29. Appa AA, Brown JS, Creasman J, Van Den Eeden SK, Subak LL, Thom DH, Ferrara A, Huang A. Clinical predictors and significance of postvoid residual volume in women with diabetes. Diabetes Res Clin Pract. 2013 Aug; 101(2):164-9. PMID: 23773505; PMCID: PMC3742560.
    30. Hess R, Huang A, Richter HE, Ghetti CC, Sung VW, Barrett-Connor E, Gregory WT, Pinkerton JV, Bradley CS, Kraus SR, Rogers RG, Subak LL, Johnson KC, Arya LA, Schembri M, Brown JS. Long-term efficacy and safety of questionnaire-based initiation of urgency urinary incontinence treatment. Am J Obstet Gynecol. 2013 Sep; 209(3):244.e1-9. PMID: 23659987; PMCID: PMC4019400.
    31. Imhoff LR, Brown JS, Creasman JM, Subak LL, Van den Eeden SK, Thom DH, Varma MG, Huang A. Fecal incontinence decreases sexual quality of life, but does not prevent sexual activity in women. Dis Colon Rectum. 2012 Oct; 55(10):1059-65. PMID: 22965405; PMCID: PMC3720983.
    32. Copeland KL, Brown JS, Creasman JM, Van Den Eeden SK, Subak LL, Thom DH, Ferrara A, Huang A. Diabetes mellitus and sexual function in middle-aged and older women. Obstet Gynecol. 2012 Aug; 120(2 Pt 1):331-40. PMID: 22825093; PMCID: PMC3404429.
    33. Huang A, Hess R, Arya LA, Richter HE, Subak LL, Bradley CS, Rogers RG, Myers DL, Johnson KC, Gregory WT, Kraus SR, Schembri M, Brown JS. Pharmacologic treatment for urgency-predominant urinary incontinence in women diagnosed using a simplified algorithm: a randomized trial. Am J Obstet Gynecol. 2012 May; 206(5):444.e1-11. PMID: 22542122; PMCID: PMC3570031.
    34. Huang A, Brown JS, Boyko EJ, Moore EE, Scholes D, Walter LC, Lin F, Vittinghoff E, Fihn SD. Clinical significance of postvoid residual volume in older ambulatory women. J Am Geriatr Soc. 2011 Aug; 59(8):1452-8. PMID: 21806559; PMCID: PMC3886558.
    35. Farhat GN, Cummings SR, Chlebowski RT, Parimi N, Cauley JA, Rohan TE, Huang A, Vitolins M, Hubbell FA, Manson JE, Cochrane BB, Lane DS, Lee JS. Sex hormone levels and risks of estrogen receptor-negative and estrogen receptor-positive breast cancers. J Natl Cancer Inst. 2011 Apr 06; 103(7):562-70. PMID: 21330633; PMCID: PMC3071353.
    36. Huang A, Subak LL, Wing R, West DS, Hernandez AL, Macer J, Grady D. An intensive behavioral weight loss intervention and hot flushes in women. Arch Intern Med. 2010 Jul 12; 170(13):1161-7. PMID: 20625026; PMCID: PMC3030922.
    37. Huang A, Moore EE, Boyko EJ, Scholes D, Lin F, Vittinghoff E, Fihn SD. Vaginal symptoms in postmenopausal women: self-reported severity, natural history, and risk factors. Menopause. 2010 Jan-Feb; 17(1):121-6. PMID: 19574936; PMCID: PMC2806500.
    38. Huang A, Luft J, Grady D, Kuppermann M. The day-to-day impact of urogenital aging: perspectives from racially/ethnically diverse women. J Gen Intern Med. 2010 Jan; 25(1):45-51. PMID: 19908103; PMCID: PMC2811605.
    39. Huang A, Sawaya GF, Vittinghoff E, Lin F, Grady D. Hot flushes, coronary heart disease, and hormone therapy in postmenopausal women. Menopause. 2009 Jul-Aug; 16(4):639-43. PMID: 19325499; PMCID: PMC2856618.
    40. Huang A, Subak LL, Thom DH, Van Den Eeden SK, Ragins AI, Kuppermann M, Shen H, Brown JS. Sexual function and aging in racially and ethnically diverse women. J Am Geriatr Soc. 2009 Aug; 57(8):1362-8. PMID: 19558473; PMCID: PMC2749599.
    41. Frick AC, Huang A, Van den Eeden SK, Knight SK, Creasman JM, Yang J, Ragins AI, Thom DH, Brown JS. Mixed urinary incontinence: greater impact on quality of life. J Urol. 2009 Aug; 182(2):596-600. PMID: 19535107; PMCID: PMC2746250.
    42. Huang A, Stewart AL, Hernandez AL, Shen H, Subak LL. Sexual function among overweight and obese women with urinary incontinence in a randomized controlled trial of an intensive behavioral weight loss intervention. J Urol. 2009 May; 181(5):2235-42. PMID: 19296980; PMCID: PMC2744348.
    43. Sawaya GF, Iwaoka-Scott AY, Kim S, Wong ST, Huang A, Washington AE, Pérez-Stable EJ. Ending cervical cancer screening: attitudes and beliefs from ethnically diverse older women. Am J Obstet Gynecol. 2009 Jan; 200(1):40.e1-7. PMID: 18976734; PMCID: PMC2643872.
    44. Learman LA, Huang A, Nakagawa S, Gregorich SE, Kuppermann M. Development and validation of a sexual functioning measure for use in diverse women's health outcome studies. Am J Obstet Gynecol. 2008 Jun; 198(6):710.e1-8; discussion 710.e8-9. PMID: 18538161.
      View in: PubMed
    45. Huang A, Pérez-Stable EJ, Kim SE, Wong ST, Kaplan CP, Walsh JM, Iwaoka-Scott AY, Sawaya GF. Preferences for human papillomavirus testing with routine cervical cancer screening in diverse older women. J Gen Intern Med. 2008 Sep; 23(9):1324-9. PMID: 18506546; PMCID: PMC2518007.
    46. Huang A, Grady D, Jacoby VL, Blackwell TL, Bauer DC, Sawaya GF. Persistent hot flushes in older postmenopausal women. Arch Intern Med. 2008 Apr 28; 168(8):840-6. PMID: 18443259.
      View in: PubMed
    47. Huang A, Yaffe K, Vittinghoff E, Kuppermann M, Addis I, Hanes V, Quan J, Grady D. The effect of ultralow-dose transdermal estradiol on sexual function in postmenopausal women. Am J Obstet Gynecol. 2008 Mar; 198(3):265.e1-7. PMID: 18313446.
      View in: PubMed
    48. Huang A, Ettinger B, Vittinghoff E, Ensrud KE, Johnson KC, Cummings SR. Endogenous estrogen levels and the effects of ultra-low-dose transdermal estradiol therapy on bone turnover and BMD in postmenopausal women. J Bone Miner Res. 2007 Nov; 22(11):1791-7. PMID: 17620054.
      View in: PubMed
    49. Huang A, Brown JS, Thom DH, Fink HA, Yaffe K. Urinary incontinence in older community-dwelling women: the role of cognitive and physical function decline. Obstet Gynecol. 2007 Apr; 109(4):909-16. PMID: 17400853.
      View in: PubMed
    50. Huang A, Grady D, Blackwell T, Bauer D. Hot flushes, bone mineral density, and fractures in older postmenopausal women. Obstet Gynecol. 2007 Apr; 109(4):841-7. PMID: 17400844.
      View in: PubMed
    51. Huang A, Brown JS, Kanaya AM, Creasman JM, Ragins AI, Van Den Eeden SK, Thom DH. Quality-of-life impact and treatment of urinary incontinence in ethnically diverse older women. Arch Intern Med. 2006 Oct 09; 166(18):2000-6. PMID: 17030834.
      View in: PubMed
    52. Huang A, Thom DH, Kanaya AM, Wassel-Fyr CL, Van den Eeden SK, Ragins AI, Subak LL, Brown JS. Urinary incontinence and pelvic floor dysfunction in Asian-American women. Am J Obstet Gynecol. 2006 Nov; 195(5):1331-7. PMID: 16643821; PMCID: PMC1630451.
    53. Huang A, Gemperli MP, Bergthold L, Singer SS, Garber A. Health plans' coverage determinations for technology-based interventions: the case of electrical bone growth stimulation. Am J Manag Care. 2004 Dec; 10(12):957-62. PMID: 15617371.
      View in: PubMed
    54. Huang A. msJAMA: Rethinking the approach to beauty in medicine. JAMA. 2001 Nov 07; 286(17):2158. PMID: 11694159.
      View in: PubMed
    55. Huang A. MSJAMA: the rise of direct-to-consumer advertising of prescription drugs in the United States. JAMA. 2000 Nov 01; 284(17):2240. PMID: 11056599.
      View in: PubMed
    56. Huang A. Continuing controversy over the international medical graduate. JAMA. 2000 Apr 05; 283(13):1746. PMID: 10755504.
      View in: PubMed
    57. Huang A. Reinventing the physician-scientist in the new era of health care. JAMA. 1999 Jan 06; 281(1):94. PMID: 9892457.
      View in: PubMed
    58. Qian SW, Burmester JK, Sun PD, Huang A, Ohlsen DJ, Suardet L, Flanders KC, Davies D, Roberts AB, Sporn MB. Characterization of mutated transforming growth factor-beta s which possess unique biological properties. Biochemistry. 1994 Oct 11; 33(40):12298-304. PMID: 7918451.
      View in: PubMed
    59. Burmester JK, Qian SW, Roberts AB, Huang A, Amatayakul-Chantler S, Suardet L, Odartchenko N, Madri JA, Sporn MB. Characterization of distinct functional domains of transforming growth factor beta. Proc Natl Acad Sci U S A. 1993 Sep 15; 90(18):8628-32. PMID: 7690965; PMCID: PMC47411.