Allan Flach, MD, PharmD

Title(s)Professor, Ophthalmology
SchoolSchool of Medicine
Address490 Illinois Street, #54H (b)
San Francisco CA 94158
Phone415-514-3105
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidency
    University of California, San FranciscoM.D.1971 Medicine
    University of California, San FranciscoPharm.D.1967 Pharmacy

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cataractogenic potential of quetiapine versus risperidone in the long-term treatment of patients with schizophrenia or schizoaffective disorder: a randomized, open-label, ophthalmologist-masked, flexible-dose, non-inferiority trial. J Psychopharmacol. 2015 Jan; 29(1):69-79. Laties AM, Flach AJ, Baldycheva I, Rak I, Earley W, Pathak S. PMID: 25315830.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    2. Amsler grids for chloroquine toxicity. Ophthalmology. 2011 Oct; 118(10):2099; author reply 2099-100. Flach AJ. PMID: 21968178.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Nonsteroidal anti-inflammatory drugs in ophthalmology. Surv Ophthalmol. 2010 Mar-Apr; 55(2):108-33. Kim SJ, Flach AJ, Jampol LM. PMID: 20159228.
      View in: PubMed   Mentions: 105     Fields:    Translation:Humans
    4. Intraoperative floppy iris syndrome: pathophysiology, prevention, and treatment. Trans Am Ophthalmol Soc. 2009 Dec; 107:234-9. Flach AJ. PMID: 20126500; PMCID: PMC2814568.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    5. Proposed mandate for instructions and labeling regarding the use of eye drops. Arch Ophthalmol. 2009 Sep; 127(9):1207-9. Flach AJ. PMID: 19752433.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Debunking myths in physician-industry conflicts of interest. Am J Ophthalmol. 2009 Mar; 147(3):562-3; author reply 563-4. Flach AJ. PMID: 19217965.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. The importance of eyelid closure and nasolacrimal occlusion following the ocular instillation of topical glaucoma medications, and the need for the universal inclusion of one of these techniques in all patient treatments and clinical studies. Trans Am Ophthalmol Soc. 2008; 106:138-45; discussion 145-8. Flach AJ. PMID: 19277229; PMCID: PMC2646444.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    8. Improving the risk-benefit relationship and informed consent for patients treated with hydroxychloroquine. Trans Am Ophthalmol Soc. 2007; 105:191-4; discussion 195-7. Flach AJ. PMID: 18427609; PMCID: PMC2258132.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    9. Misuse and abuse of topically applied nonsteroidal anti-inflammatory drugs. Cornea. 2006 Dec; 25(10):1265-6. Flach AJ. PMID: 17172917.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Choroidal detachment following the use of tamsulosin (Flomax). Am J Ophthalmol. 2007 Feb; 143(2):351-3. Shapiro BL, Petrovic V, Lee SE, Flach A, McCaffery S, O'Brien JM. PMID: 17258532.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    11. Comparison of ketorolac tromethamine, diclofenac sodium, and loteprednol etabonate in an animal model of ocular inflammation. J Ocul Pharmacol Ther. 2006 Jun; 22(3):155-9. Waterbury LD, Flach AJ. PMID: 16808675.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    12. Efficacy of low concentrations of ketorolac tromethamine in animal models of ocular inflammation. J Ocul Pharmacol Ther. 2004 Aug; 20(4):345-52. Waterbury LD, Flach AJ. PMID: 15321029.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    13. Does medical treatment influence the success of trabeculectomy? Trans Am Ophthalmol Soc. 2004; 102:219-23; discussion 223-4. Flach AJ. PMID: 15747760; PMCID: PMC1280102.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    14. Delta-9-tetrahydrocannabinol (THC) in the treatment of end-stage open-angle glaucoma. Trans Am Ophthalmol Soc. 2002; 100:215-22; discussion 222-4. Flach AJ. PMID: 12545695; PMCID: PMC1358964.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    15. Additional factors linking corneal melting to topical nonsteroidal anti-inflammatory drugs. Arch Ophthalmol. 2001 Jul; 119(7):1085. Flach A. PMID: 11448339.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. Corneal melts associated with topically applied nonsteroidal anti-inflammatory drugs. Trans Am Ophthalmol Soc. 2001; 99:205-10; discussion 210-2. Flach AJ. PMID: 11797308; PMCID: PMC1359011.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    17. Topically applied nonsteroidal anti-inflammatory drugs and corneal problems: an interim review and comment. Ophthalmology. 2000 Jul; 107(7):1224-6. Flach A. PMID: 10889089.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    18. Incidence of postoperative posterior capsular opacification following treatment with diclofenac 0.1% and ketorolac 0.5% ophthalmic solutions: 3-year randomized, double-masked, prospective clinical investigation. Trans Am Ophthalmol Soc. 2000; 98:101-5; discussion 105-7. Flach AJ, Dolan BJ. PMID: 11190013; PMCID: PMC1298216.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    19. Comparative effects of ketorolac 0.5% or diclofenac 0.1% ophthalmic solutions on inflammation after cataract surgery. Ophthalmology. 1998 Sep; 105(9):1775-9. Flach AJ, Dolan BJ, Donahue ME, Faktorovich EG, Gonzalez GA. PMID: 9754191.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    20. The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery. Trans Am Ophthalmol Soc. 1998; 96:557-634. Flach AJ. PMID: 10360304; PMCID: PMC1298410.
      View in: PubMed   Mentions: 84     Fields:    Translation:Humans
    21. Acetazolamide treatment of CME in patients with uveitis. Ophthalmology. 1996 Nov; 103(11):1715-6; author reply 1716-7. Flach A. PMID: 8942859.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. Ocular pharmacology and toxicology. Ophthalmology. 1996 Aug; 103(8 Suppl):S118-42. Flach AJ. PMID: 8764773.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. Topical nonsteroidal antiinflammatory drugs for ophthalmic use. Int Ophthalmol Clin. 1996; 36(2):77-83. Flach AJ. PMID: 8950635.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    24. Stevens-Johnson syndrome associated with methazolamide treatment reported in two Japanese-American women. Ophthalmology. 1995 Nov; 102(11):1677-80. Flach AJ, Smith RE, Fraunfelder FT. PMID: 9098261.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    25. Efficacy of apraclonidine ophthalmic solution (iopidine) in presumed silicon oil-induced glaucoma and primary open-angle glaucoma. Surv Ophthalmol. 1995 Jul-Aug; 40(1):84-5. Flach AJ. PMID: 8545811.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Pet flea and tick collar-induced anisocoria. Arch Ophthalmol. 1994 May; 112(5):586. Flach AJ, Donahue ME. PMID: 8185512.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    27. Systemic toxicity. Associated with topical ophthalmic medications. J Fla Med Assoc. 1994 Apr; 81(4):256-60. Flach AJ. PMID: 8046365.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    28. Clear evidence that long-term, low-dose tamoxifen treatment can induce ocular toxicity: a prospective study of 63 patients. Surv Ophthalmol. 1994 Jan-Feb; 38(4):392-3. Flach AJ. PMID: 8160114.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    29. Nonsteroidal anti-inflammatory drugs in ophthalmology. Int Ophthalmol Clin. 1993; 33(4):1-7. Flach AJ. PMID: 8258490.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    30. Progression of amiodarone induced cataracts. Doc Ophthalmol. 1993; 83(4):323-9. Flach AJ, Dolan BJ. PMID: 8223102.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    31. Nerve terminal degeneration in the rat iris observed following chronic topical 2% epinephrine and 0.1% dipivalyl epinephrine: a quantitative comparison of electron microscopic observations and tissue norepinephrine levels. Graefes Arch Clin Exp Ophthalmol. 1992; 230(6):575-9. Flach AJ, Donahue ME, Wood IS. PMID: 1427143.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    32. Effects of topically applied 2% epinephrine and 0.1% dipivalyl epinephrine on the adrenergic nerves as revealed by histofluorescence. Ophthalmologica. 1992; 205(2):96-9. Flach AJ, Donahue ME. PMID: 1475087.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    33. Cyclo-oxygenase inhibitors in ophthalmology. Surv Ophthalmol. 1992 Jan-Feb; 36(4):259-84. Flach AJ. PMID: 1549810.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    34. Improvement in visual acuity in chronic aphakic and pseudophakic cystoid macular edema after treatment with topical 0.5% ketorolac tromethamine. Am J Ophthalmol. 1991 Nov 15; 112(5):514-9. Flach AJ, Jampol LM, Weinberg D, Kraff MC, Yannuzzi LA, Campo RV, Neumann AC, Cupples HP, Lefler WH, Pulido JS, et al. PMID: 1951587.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCTClinical Trials
    35. Glaucoma treatment and pregnancy. Arch Ophthalmol. 1991 Apr; 109(4):463. Flach AJ. PMID: 2012532.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    36. Amiodarone-induced lens opacities: an 8-year follow-up study. Arch Ophthalmol. 1990 Dec; 108(12):1668-9. Flach AJ, Dolan BJ. PMID: 2256828.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    37. Prophylaxis of aphakic cystoid macular edema without corticosteroids. A paired-comparison, placebo-controlled double-masked study. Ophthalmology. 1990 Oct; 97(10):1253-8. Flach AJ, Stegman RC, Graham J, Kruger LP. PMID: 2243674.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    38. Episcleritis, conjunctivitis, and keratitis as ocular manifestations of Lyme disease. Ophthalmology. 1990 Aug; 97(8):973-5. Flach AJ, Lavoie PE. PMID: 2205817.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    39. The effect of ketorolac tromethamine in reducing postoperative inflammation: double-mask parallel comparison with dexamethasone. Ann Ophthalmol. 1989 Nov; 21(11):407-11. Flach AJ, Jaffe NS, Akers WA. PMID: 2619149.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    40. Cystoid macular edema following cataract surgery. Arch Ophthalmol. 1989 Feb; 107(2):166-7. Flach AJ. PMID: 2916962.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    41. The effect of ketorolac tromethamine solution 0.5% in reducing postoperative inflammation after cataract extraction and intraocular lens implantation. Ophthalmology. 1988 Sep; 95(9):1279-84. Flach AJ, Lavelle CJ, Olander KW, Retzlaff JA, Sorenson LW. PMID: 3062540.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCTClinical Trials
    42. The quantitative effect of 0.5% ketorolac tromethamine solution and 0.1% dexamethasone sodium phosphate solution on postsurgical blood-aqueous barrier. Arch Ophthalmol. 1988 Apr; 106(4):480-3. Flach AJ, Kraff MC, Sanders DR, Tanenbaum L. PMID: 3355415.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    43. Quantitative assessment of postsurgical breakdown of the blood-aqueous barrier following administration of 0.5% ketorolac tromethamine solution. A double-masked, paired comparison with vehicle-placebo solution study. Arch Ophthalmol. 1988 Mar; 106(3):344-7. Flach AJ, Graham J, Kruger LP, Stegman RC, Tanenbaum L. PMID: 3345153.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    44. Topical prostaglandin E2 effects on normal human intraocular pressure. J Ocul Pharmacol. 1988; 4(1):13-8. Flach AJ, Eliason JA. PMID: 3171331.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    45. Effectiveness of ketorolac tromethamine 0.5% ophthalmic solution for chronic aphakic and pseudophakic cystoid macular edema. Am J Ophthalmol. 1987 Apr 15; 103(4):479-86. Flach AJ, Dolan BJ, Irvine AR. PMID: 3551617.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCTClinical Trials
    46. Ocular hypertensive responses in pigmented rabbits following different methods of waterloading. J Ocul Pharmacol. 1986; 2(4):313-7. Flach AJ, Peterson JS, Donahue ME. PMID: 3503115.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    47. Dangers of ocular instillation of medications. West J Med. 1985 Sep; 143(3):391. Flach AJ. PMID: 4049862; PMCID: PMC1306347.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    48. Amiodarone keratopathy and lens opacities. J Am Optom Assoc. 1985 Jun; 56(6):468-70. Dolan BJ, Flach AJ, Peterson JS. PMID: 4008856.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    49. The therapy of Adie's syndrome with dilute pilocarpine hydrochloride solutions. J Ocul Pharmacol. 1985; 1(4):353-62. Flach AJ, Dolan BJ. PMID: 3880084.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    50. Anterior subcapsular cataracts: a review of potential etiologies. Ann Ophthalmol. 1985 Jan; 17(1):78-80. Flach AJ, Peterson JS, Dolan BJ. PMID: 3977225.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    51. Adie's syndrome: a medical treatment for symptomatic patients. Ann Ophthalmol. 1984 Dec; 16(12):1151-4. Flach AJ, Dolan BJ. PMID: 6532290.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    52. The use of amiodarone in children. Pacing Clin Electrophysiol. 1984 Nov; 7(6 Pt 1):1086-7. Flach AJ, Dolan B, Sudduth B. PMID: 6209628.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    53. Local ocular hypotensive effect of topically applied acetazolamide. Am J Ophthalmol. 1984 Jul 15; 98(1):66-72. Flach AJ, Peterson JS, Seligmann KA. PMID: 6742080.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    54. Ophthalmology-Important Advances in Clinical Medicine: Severe Systemic Effects From Topically Applied beta-Adrenergic Blocking Agents. West J Med. 1984 Feb; 140(2):269. Flach AJ. PMID: 18749497; PMCID: PMC1021611.
      View in: PubMed   Mentions: 1     Fields:    
    55. Post-ganglionic chemical sympathectomy of the cat nictitating membrane following systemic epinephrine: degeneration of nerve terminals followed by regeneration. Exp Eye Res. 1983 Nov; 37(5):447-53. Flach AJ, Roizen MF, Wood IS, Peterson JS. PMID: 6671473.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    56. Amiodarone-induced lens opacities. Arch Ophthalmol. 1983 Oct; 101(10):1554-6. Flach AJ, Dolan BJ, Sudduth B, Weddell J. PMID: 6626008.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    57. A registry of potential product substitutions of particular danger for ophthalmology. Am J Ophthalmol. 1983 Sep; 96(3):404-5. Flach AJ. PMID: 6614121.
      View in: PubMed   Mentions:    Fields:    
    58. Ptosis in the rat following topically administered 2% epinephrine. Invest Ophthalmol Vis Sci. 1983 Jun; 24(6):766-71. Flach AJ, Peterson JS, Roizen MF, Wood IS. PMID: 6406386.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    59. Eyewash mistaken for contact lens soaking solution. Am J Ophthalmol. 1983 Jun; 95(6):850-1. Flach AJ, Sorenson JA. PMID: 6859204.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    60. Chromatopsia related to afterimages. Am J Ophthalmol. 1982 Dec; 94(6):811-2. Flach AJ, Stone DR, Becker CE, Peterson JS. PMID: 6983833.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    61. Cortisporin dispensing error. Am J Ophthalmol. 1982 Oct; 94(4):565-7. Flach A, Murphy A. PMID: 6291395.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    62. Fatal aplastic anemia following topical administration of ophthalmic chloramphenicol. Am J Ophthalmol. 1982 Sep; 94(3):420-2. Flach AJ. PMID: 7124889.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    63. Photosensitivity to topically applied sulfisoxazole ointment: evidence for a phototoxic reaction. Arch Ophthalmol. 1982 Aug; 100(8):1286-7. Flach AJ, Peterson JS, Mathias CG. PMID: 7103813.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    64. Chloramphenicol and aplastic anemia. Am J Ophthalmol. 1982 May; 93(5):664-6. Flach AJ. PMID: 7081370.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    65. Photosensitivity to sulfisoxazole ointment. Arch Ophthalmol. 1981 Apr; 99(4):609-10. Flach A. PMID: 7224931.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    66. Degeneration of nerve terminals in cats following systemic epinephrine: depletion of tissue norepinephrine correlated with ultrastructural changes. Exp Eye Res. 1981 Apr; 32(4):389-94. Flach AJ, Peterson JS, Wood I, Roizen MF. PMID: 7238624.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    67. Supersensitivity to topical epinephrine after long-term epinephrine therapy. Arch Ophthalmol. 1980 Mar; 98(3):482-3. Flach AJ, Kramer SG. PMID: 7362503.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    68. The fluorescein appearance test for lacrimal obstruction. Ann Ophthalmol. 1979 Feb; 11(2):237-42. Flach A. PMID: 434742.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    69. An electron microscopic study of degeneration of nerve terminals after administration of epinephrine. Exp Eye Res. 1978 Oct; 27(4):377-85. Flach A, Wood I. PMID: 729652.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    70. Symblepharon in sarcoidosis. Am J Ophthalmol. 1978 Feb; 85(2):210-4. Flach A. PMID: 623192.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    71. Fluorescein oropharyngoscopy. Am J Ophthalmol. 1976 Dec; 82(6):940-2. Flach A. PMID: 998711.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    72. The pilocarpine Ocusert Delivery System. Trans Pac Coast Otoophthalmol Soc Annu Meet. 1974; 55:179-208. Flach A. PMID: 4480721.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    73. [Intra vitam microscopic observations on capillaries and arterioles of the periphery of the lung following various stimuli]. Bibl Anat. 1965; 7:101-5. Flach A. PMID: 5860716.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
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