Andrea Gramatica, PhD

Title(s)Postdoctoral Scholar, Gladstone Institutes
SchoolSchool of Medicine
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    Collapse Biography 
    Collapse Education and Training
    Humboldt University Berlin, Berlin, GermanyPhD2014Cell Biology
    University of Milano Bicocca, Milan, ItalyMS2010Industrial Biotechnology
    University of Milano Bicocca, Milan, ItalyBS2008Biotechnology
    Collapse Awards and Honors
    UCSF-Gladstone Center for AIDS Research2019Early Career Research Excellence Award in Basic Science
    Gladstone Institutes2017Gilead HIV Cure Mentored Scientist Award
    Humboldt University Berlin2010  - 2013Marie Curie Actions fellowships
    University of Milano Bicocca2009  - 2010ERASMUS Fellowship

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. HIV-specific T cell responses reflect substantive in vivo interactions with antigen despite long-term therapy. JCI Insight. 2021 02 08; 6(3). Stevenson EM, Ward AR, Truong R, Thomas AS, Huang SH, Dilling TR, Terry S, Bui JK, Mota TM, Danesh A, Lee GQ, Gramatica A, Khadka P, Alberto WDC, Gandhi RT, McMahon DK, Lalama CM, Bosch RJ, Macatangay B, Cyktor JC, Eron JJ, Mellors JW, Jones RB, AIDS Clinical Trials Group A5321 Team . PMID: 33400687.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    2. Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity Ex Vivo and In Vivo. J Virol. 2021 Feb 03. Gramatica A, Schwarzer R, Brantley W, Varco-Merth B, Sperber HS, Hull PA, Montano M, Migueles SA, Rosenthal D, Hogan LE, Johnson JR, Packard TA, Grimmett ZW, Herzig E, Besnard E, Nekorchuk M, Hsiao F, Deeks SG, Snape M, Kiernan B, Roan NR, Lifson JD, Estes JD, Picker LJ, Verdin E, Krogan NJ, Henrich TJ, Connors M, Ott M, Pillai SK, Okoye AA, Greene WC. PMID: 33536176.
      View in: PubMed   Mentions:    Fields:    
    3. Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection. PLoS Pathog. 2020 04; 16(4):e1008450. Hsiao F, Frouard J, Gramatica A, Xie G, Telwatte S, Lee GQ, Roychoudhury P, Schwarzer R, Luo X, Yukl SA, Lee S, Hoh R, Deeks SG, Jones RB, Cavrois M, Greene WC, Roan NR. PMID: 32353080.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    4. Reduce and Control: A Combinatorial Strategy for Achieving Sustained HIV Remissions in the Absence of Antiretroviral Therapy. Viruses. 2020 02 08; 12(2). Schwarzer R, Gramatica A, Greene WC. PMID: 32046251.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    5. Attacking Latent HIV with convertibleCAR-T Cells, a Highly Adaptable Killing Platform. Cell. 2019 10 31; 179(4):880-894.e10. Herzig E, Kim KC, Packard TA, Vardi N, Schwarzer R, Gramatica A, Deeks SG, Williams SR, Landgraf K, Killeen N, Martin DW, Weinberger LS, Greene WC. PMID: 31668804.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    6. The HIV gp41 Fusion Protein Inhibits T-Cell Activation through the Lentiviral Lytic Peptide 2 Motif. Biochemistry. 2019 02 12; 58(6):818-832. Klug YA, Schwarzer R, Rotem E, Charni M, Nudelman A, Gramatica A, Zarmi B, Rotter V, Shai Y. PMID: 30602116.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    7. Distinct chromatin functional states correlate with HIV latency reactivation in infected primary CD4+ T cells. Elife. 2018 05 01; 7. Battivelli E, Dahabieh MS, Abdel-Mohsen M, Svensson JP, Tojal Da Silva I, Cohn LB, Gramatica A, Deeks S, Greene WC, Pillai SK, Verdin E. PMID: 29714165.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    8. D-109 Defining a potent new class of latency reversing agents devoid of toxicity and detrimental cell activation that enhance CTL/NK cell killing. JAIDS Journal of Acquired Immune Deficiency Syndromes. 2018 Apr 1; 77(&NA;):41. Andrea Gramatica, Roland Schwarzer, Mauricio Montano, Eytan Herzig, Thomas Packard, Warner C. Greene. .
      View in: Publisher Site   Mentions:
    9. D-106 Chromatin Functional States Correlate with the Reversal of Latently HIV-1 Infected Primary CD4+ T cells. JAIDS Journal of Acquired Immune Deficiency Syndromes. 2018 Apr 1; 77(&NA;):40. Emilie Battivelli, Matthew S. Dahabieh, Mohamed Abdel-Mohsen, J. Peter Svensson, Israel Tojal Da Silva, Lilian B. Cohn, Andrea Gramatica, Steven Deeks, Warner Greene, Satish K. Pillai, Eric Verdin. .
      View in: Publisher Site   Mentions:
    10. OP 1.3 Identification of a promising new class of latency reversing agents. Journal of virus eradication. 2017 Dec 1; 3:1-2. A. Gramatica, W. Greene, R. Schwarzer, M. Montano, T. Packard, E. Herzig, Warner Greene. .
      View in: Publisher Site   Mentions:
    11. SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency. . 2017 May 10; 21(5):569-579.e6. Boehm D, Jeng M, Camus G, Gramatica A, Schwarzer R, Johnson JR, Hull PA, Montano M, Sakane N, Pagans S, Godin R, Deeks SG, Krogan NJ, Greene WC, Ott M. PMID: 28494238.
      View in: PubMed   Mentions:
    12. The mTOR Complex Controls HIV Latency. . 2016 Dec 14; 20(6):785-797. Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, Krogan NJ, Siliciano RF, Weissman JS, Verdin E. PMID: 27978436.
      View in: PubMed   Mentions:
    13. Lymphoid tissue and blood CD4 T cells respond differently to latency-reversing agents: are we testing the right cells?. Journal of virus eradication. 2015 Dec 1; 1:11. A. Gramatica, W.C. Greene, M. Montano. .
      View in: Publisher Site   Mentions:
    14. Binding of alphaherpesvirus glycoprotein H to surface a4ß1-integrins activates calcium-signaling pathways and induces phosphatidylserine exposure on the plasma membrane. mBio. 2015 Oct 20; 6(5):e01552-15. Azab W, Gramatica A, Herrmann A, Osterrieder N. PMID: 26489864.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    15. Time-controlled phagocytosis of asymmetric liposomes: Application to phosphatidylserine immunoliposomes binding HIV-1 virus-like particles. Nanomedicine. 2015 Nov; 11(8):1985-92. Petazzi RA, Gramatica A, Herrmann A, Chiantia S. PMID: 26115636.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    16. The HIV-1 envelope transmembrane domain binds TLR2 through a distinct dimerization motif and inhibits TLR2-mediated responses. PLoS Pathog. 2014 Aug; 10(8):e1004248. Reuven EM, Ali M, Rotem E, Schwarzer R, Schwarzter R, Gramatica A, Futerman AH, Shai Y. PMID: 25121610.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    17. The cholesterol-binding motif of the HIV-1 glycoprotein gp41 regulates lateral sorting and oligomerization. Cell Microbiol. 2014 Oct; 16(10):1565-81. Schwarzer R, Levental I, Gramatica A, Scolari S, Buschmann V, Veit M, Herrmann A. PMID: 24844300.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    18. aEnv-decorated phosphatidylserine liposomes trigger phagocytosis of HIV-virus-like particles in macrophages. Nanomedicine. 2014 Jul; 10(5):981-9. Gramatica A, Petazzi RA, Lehmann MJ, Ziomkowska J, Herrmann A, Chiantia S. PMID: 24589930.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    19. Mimicking Apoptosis using Asymmetric Liposomes: A Therapeutic Approach Against Hiv-1 Infection. Biophysical Journal. 2014 Jan 1; 106(2):622a. Andrea Gramatica, Roberto A. Petazzi, Maik J. Lehmann, Joanna Ziomkowska, Andreas Herrmann, Salvatore Chiantia. .
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    20. New Insights on the Versatile Role of the Cholesterol Binding Motif of the HIV-1 Glycoprotein Gp41. Biophysical Journal. 2014 Jan 1; 106(2):62a. Roland Schwarzer, Andreas Herrmann, Ilya Levental, Andrea Gramatica. .
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    21. Calcium-Mediated Fusion between Endo-Lysosomal Compartments Enhances Virus-Like Particles Release. Biophysical Journal. 2013 Jan 1; 104(2):417a. Andrea Gramatica, Maik J. Lehmann, Roland Schwarzer, Andreas Herrmann. .
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    22. Intracellular Dynamics of HIV-Gag: The Role of Calcium and the Activation of Phospholipase C. Biophysical Journal. 2012 Jan 1; 102(3):640a. Andrea Gramatica, Roland Schwarzer, Andreas Herrmann. .
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    23. Reduction-sensitive liposomes from a multifunctional lipid conjugate and natural phospholipids: reduction and release kinetics and cellular uptake. Langmuir. 2011 Sep 06; 27(17):10820-9. Goldenbogen B, Brodersen N, Gramatica A, Loew M, Liebscher J, Herrmann A, Egger H, Budde B, Arbuzova A. PMID: 21819046.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
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