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Making fluorescence-based integrative structures and associated kinetic information accessible. Nat Methods. 2024 Sep 30.
Hanke CA, Westbrook JD, Webb BM, Peulen TO, Lawson CL, Sali A, Berman HM, Seidel CAM, Vallat B. PMID: 39349602.
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PubMed Mentions: Fields:
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Structure and inhibition mechanisms of Mycobacterium tuberculosis essential transporter efflux protein A. bioRxiv. 2024 Sep 05.
Khandelwal NK, Gupta M, Gomez JE, Barkho S, Guan Z, Eng AY, Kawate T, Balasubramani SG, Sali A, Hung DT, Stroud RM. PMID: 39282303; PMCID: PMC11398473.
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PubMed Mentions:
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The molecular architecture of the nuclear basket. Cell. 2024 Sep 19; 187(19):5267-5281.e13.
Singh D, Soni N, Hutchings J, Echeverria I, Shaikh F, Duquette M, Suslov S, Li Z, van Eeuwen T, Molloy K, Shi Y, Wang J, Guo Q, Chait BT, Fernandez-Martinez J, Rout MP, Sali A, Villa E. PMID: 39127037; PMCID: PMC11416316.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Integrative spatiotemporal modeling of biomolecular processes: application to the assembly of the Nuclear Pore Complex. bioRxiv. 2024 Aug 08.
Latham AP, Tempkin JOB, Otsuka S, Zhang W, Ellenberg J, Sali A. PMID: 39149317; PMCID: PMC11326192.
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PubMed Mentions:
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Multiscale photocatalytic proximity labeling reveals cell surface neighbors on and between cells. Science. 2024 Jul 19; 385(6706):eadl5763.
Lin Z, Schaefer K, Lui I, Yao Z, Fossati A, Swaney DL, Palar A, Sali A, Wells JA. PMID: 39024454.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Cell Maps for Artificial Intelligence: AI-Ready Maps of Human Cell Architecture from Disease-Relevant Cell Lines. bioRxiv. 2024 May 24.
Clark T, Mohan J, Schaffer L, Obernier K, Al Manir S, Churas CP, Dailamy A, Doctor Y, Forget A, Hansen JN, Hu M, Lenkiewicz J, Levinson MA, Marquez C, Nourreddine S, Niestroy J, Pratt D, Qian G, Thaker S, Bélisle-Pipon JC, Brandt C, Chen J, Ding Y, Fodeh S, Krogan N, Lundberg E, Mali P, Payne-Foster P, Ratcliffe S, Ravitsky V, Sali A, Schulz W, Ideker T. PMID: 38826258; PMCID: PMC11142054.
View in:
PubMed Mentions:
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Illuminating the function of the orphan transporter, SLC22A10, in humans and other primates. Nat Commun. 2024 May 23; 15(1):4380.
Yee SW, Ferrández-Peral L, Alentorn-Moron P, Fontsere C, Ceylan M, Koleske ML, Handin N, Artegoitia VM, Lara G, Chien HC, Zhou X, Dainat J, Zalevsky A, Sali A, Brand CM, Wolfreys FD, Yang J, Gestwicki JE, Capra JA, Artursson P, Newman JW, Marquès-Bonet T, Giacomini KM. PMID: 38782905; PMCID: PMC11116522.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus. Elife. 2024 May 07; 12.
Ketaren NE, Mast FD, Fridy PC, Olivier JP, Sanyal T, Sali A, Chait BT, Rout MP, Aitchison JD. PMID: 38712823; PMCID: PMC11076045.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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The Molecular Architecture of the Nuclear Basket. bioRxiv. 2024 Mar 28.
Singh D, Soni N, Hutchings J, Echeverria I, Shaikh F, Duquette M, Suslov S, Li Z, van Eeuwen T, Molloy K, Shi Y, Wang J, Guo Q, Chait BT, Fernandez-Martinez J, Rout MP, Sali A, Villa E. PMID: 38586009; PMCID: PMC10996695.
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PubMed Mentions:
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Identification of thrombosis-related conformational binding epitopes on domain I of β2-glycoprotein I. Thromb Res. 2024 May; 237:145-147.
Kim SJ, Schneidman-Duhovny D, de Groot PG, Urbanus RT, Carter L, de Laat-Kremers R, Weiss TM, Chan MK, Sali A, Rand JH, de Laat B. PMID: 38593525.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
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IHMCIF: An Extension of the PDBx/mmCIF Data Standard for Integrative Structure Determination Methods. J Mol Biol. 2024 Sep 01; 436(17):168546.
Vallat B, Webb BM, Westbrook JD, Goddard TD, Hanke CA, Graziadei A, Peisach E, Zalevsky A, Sagendorf J, Tangmunarunkit H, Voinea S, Sekharan M, Yu J, Bonvin AAMJJ, DiMaio F, Hummer G, Meiler J, Tajkhorshid E, Ferrin TE, Lawson CL, Leitner A, Rappsilber J, Seidel CAM, Jeffries CM, Burley SK, Hoch JC, Kurisu G, Morris K, Patwardhan A, Velankar S, Schwede T, Trewhella J, Kesselman C, Berman HM, Sali A. PMID: 38508301; PMCID: PMC11377171.
View in:
PubMed Mentions:
1 Fields:
Translation:
Cells
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In situ structure of actin remodeling during glucose-stimulated insulin secretion using cryo-electron tomography. Nat Commun. 2024 Feb 12; 15(1):1311.
Li W, Li A, Yu B, Zhang X, Liu X, White KL, Stevens RC, Baumeister W, Sali A, Jasnin M, Sun L. PMID: 38346988; PMCID: PMC10861521.
View in:
PubMed Mentions: Fields:
Translation:
Cells
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Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus. bioRxiv. 2024 Jan 29.
Ketaren NE, Mast FD, Fridy PC, Olivier JP, Sanyal T, Sali A, Chait BT, Rout MP, Aitchison JD. PMID: 37503298; PMCID: PMC10369967.
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PubMed Mentions:
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Structural basis of prostaglandin efflux by MRP4. Nat Struct Mol Biol. 2024 Apr; 31(4):621-632.
Pourmal S, Green E, Bajaj R, Chemmama IE, Knudsen GM, Gupta M, Sali A, Cheng Y, Craik CS, Kroetz DL, Stroud RM. PMID: 38216659; PMCID: PMC11145372.
View in:
PubMed Mentions:
1 Fields:
-
Integrative spatiotemporal map of nucleocytoplasmic transport. bioRxiv. 2024 Jan 02.
Raveh B, Eliasian R, Rashkovits S, Russel D, Hayama R, Sparks SE, Singh D, Lim R, Villa E, Rout MP, Cowburn D, Sali A. PMID: 38260487; PMCID: PMC10802240.
View in:
PubMed Mentions:
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Structures, functions and adaptations of the human LINE-1 ORF2 protein. Nature. 2024 Feb; 626(7997):194-206.
Baldwin ET, van Eeuwen T, Hoyos D, Zalevsky A, Tchesnokov EP, Sánchez R, Miller BD, Di Stefano LH, Ruiz FX, Hancock M, Isik E, Mendez-Dorantes C, Walpole T, Nichols C, Wan P, Riento K, Halls-Kass R, Augustin M, Lammens A, Jestel A, Upla P, Xibinaku K, Congreve S, Hennink M, Rogala KB, Schneider AM, Fairman JE, Christensen SM, Desrosiers B, Bisacchi GS, Saunders OL, Hafeez N, Miao W, Kapeller R, Zaller DM, Sali A, Weichenrieder O, Burns KH, Götte M, Rout MP, Arnold E, Greenbaum BD, Romero DL, LaCava J, Taylor MS. PMID: 38096902; PMCID: PMC10830420.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Multi-scale photocatalytic proximity labeling reveals cell surface neighbors on and between cells. bioRxiv. 2023 Oct 29.
Lin Z, Schaefer K, Lui I, Yao Z, Fossati A, Swaney DL, Palar A, Sali A, Wells JA. PMID: 37961561; PMCID: PMC10634877.
View in:
PubMed Mentions:
1
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Implications of a multiscale structure of the yeast nuclear pore complex. Mol Cell. 2023 09 21; 83(18):3283-3302.e5.
Akey CW, Echeverria I, Ouch C, Nudelman I, Shi Y, Wang J, Chait BT, Sali A, Fernandez-Martinez J, Rout MP. PMID: 37738963; PMCID: PMC10630966.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Illuminating the Function of the Orphan Transporter, SLC22A10 in Humans and Other Primates. Res Sq. 2023 Sep 14.
Yee SW, Ferrández-Peral L, Alentorn P, Fontsere C, Ceylan M, Koleske ML, Handin N, Artegoitia VM, Lara G, Chien HC, Zhou X, Dainat J, Zalevsky A, Sali A, Brand CM, Capra JA, Artursson P, Newman JW, Marques-Bonet T, Giacomini KM. PMID: 37790518; PMCID: PMC10543398.
View in:
PubMed Mentions:
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Illuminating the Function of the Orphan Transporter, SLC22A10 in Humans and Other Primates. bioRxiv. 2023 Aug 12.
Yee SW, Ferrández-Peral L, Alentorn P, Fontsere C, Ceylan M, Koleske ML, Handin N, Artegoitia VM, Lara G, Chien HC, Zhou X, Dainat J, Zalevsky A, Sali A, Brand CM, Capra JA, Artursson P, Newman JW, Marques-Bonet T, Giacomini KM. PMID: 37609337; PMCID: PMC10441401.
View in:
PubMed Mentions:
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Soft X-ray Tomography for Mapping and Quantifying Intracellular Organelle Interactions. Microsc Microanal. 2023 Jul 22; 29(Supplement_1):1181.
Loconte V, Singla J, Li A, Chen JH, Ekman A, McDermott G, Sali A, Gros ML, White KL, Larabell CA. PMID: 37613466.
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PubMed Mentions: Fields:
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Conformational Dynamics of the Activated GLP-1 Receptor-Gs Complex Revealed by Cross-Linking Mass Spectrometry and Integrative Structure Modeling. ACS Cent Sci. 2023 May 24; 9(5):992-1007.
Yuan S, Xia L, Wang C, Wu F, Zhang B, Pan C, Fan Z, Lei X, Stevens RC, Sali A, Sun L, Shui W. PMID: 37252352; PMCID: PMC10214531.
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PubMed Mentions:
2
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Dynamic molecular mechanism of the nuclear pore complex permeability barrier. bioRxiv. 2023 Apr 14.
Kozai T, Fernandez-Martinez J, van Eeuwen T, Gallardo P, Kapinos LE, Mazur A, Zhang W, Tempkin J, Panatala R, Delgado-Izquierdo M, Raveh B, Sali A, Chait BT, Veenhoff LM, Rout MP, Lim RYH. PMID: 37066338; PMCID: PMC10103940.
View in:
PubMed Mentions:
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In situ structure of actin remodeling during glucose-stimulated insulin secretion using cryo-electron tomography. Res Sq. 2023 Apr 04.
Li W, Li A, Yu B, Zhang X, Liu X, White K, Stevens R, Baumeister W, Sali A, Jasnin M, Sun L. PMID: 37066286; PMCID: PMC10104243.
View in:
PubMed Mentions:
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ModelCIF: An Extension of PDBx/mmCIF Data Representation for Computed Structure Models. J Mol Biol. 2023 07 15; 435(14):168021.
Vallat B, Tauriello G, Bienert S, Haas J, Webb BM, Žídek A, Zheng W, Peisach E, Piehl DW, Anischanka I, Sillitoe I, Tolchard J, Varadi M, Baker D, Orengo C, Zhang Y, Hoch JC, Kurisu G, Patwardhan A, Velankar S, Burley SK, Sali A, Schwede T, Berman HM, Westbrook JD. PMID: 36828268; PMCID: PMC10293049.
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PubMed Mentions:
8 Fields:
Translation:
Cells
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Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13. Nat Struct Mol Biol. 2023 03; 30(3):296-308.
Kim SK, Dickinson MS, Finer-Moore J, Guan Z, Kaake RM, Echeverria I, Chen J, Pulido EH, Sali A, Krogan NJ, Rosenberg OS, Stroud RM. PMID: 36782050; PMCID: PMC10312659.
View in:
PubMed Mentions:
10 Fields:
Translation:
Cells
-
Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13. bioRxiv. 2023 Jan 28.
Kim SK, Dickinson MS, Finer-Moore J, Guan Z, Kaake RM, Echeverria I, Chen J, Pulido EH, Sali A, Krogan NJ, Rosenberg OS, Stroud RM. PMID: 36747776; PMCID: PMC9900942.
View in:
PubMed Mentions:
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RCSB Protein Data Bank (RCSB.org): delivery of experimentally-determined PDB structures alongside one million computed structure models of proteins from artificial intelligence/machine learning. Nucleic Acids Res. 2023 01 06; 51(D1):D488-D508.
Burley SK, Bhikadiya C, Bi C, Bittrich S, Chao H, Chen L, Craig PA, Crichlow GV, Dalenberg K, Duarte JM, Dutta S, Fayazi M, Feng Z, Flatt JW, Ganesan S, Ghosh S, Goodsell DS, Green RK, Guranovic V, Henry J, Hudson BP, Khokhriakov I, Lawson CL, Liang Y, Lowe R, Peisach E, Persikova I, Piehl DW, Rose Y, Sali A, Segura J, Sekharan M, Shao C, Vallat B, Voigt M, Webb B, Westbrook JD, Whetstone S, Young JY, Zalevsky A, Zardecki C. PMID: 36420884; PMCID: PMC9825554.
View in:
PubMed Mentions:
151 Fields:
Translation:
Cells
-
A quantitative map of nuclear pore assembly reveals two distinct mechanisms. Nature. 2023 01; 613(7944):575-581.
Otsuka S, Tempkin JOB, Zhang W, Politi AZ, Rybina A, Hossain MJ, Kueblbeck M, Callegari A, Koch B, Morero NR, Sali A, Ellenberg J. PMID: 36599981; PMCID: PMC9849139.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Electron microscopy holdings of the Protein Data Bank: the impact of the resolution revolution, new validation tools, and implications for the future. Biophys Rev. 2022 Dec; 14(6):1281-1301.
Burley SK, Berman HM, Chiu W, Dai W, Flatt JW, Hudson BP, Kaelber JT, Khare SD, Kulczyk AW, Lawson CL, Pintilie GD, Sali A, Vallat B, Westbrook JD, Young JY, Zardecki C. PMID: 36474933; PMCID: PMC9715422.
View in:
PubMed Mentions:
20
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RCSB Protein Data bank: Tools for visualizing and understanding biological macromolecules in 3D. Protein Sci. 2022 12; 31(12):e4482.
Burley SK, Bhikadiya C, Bi C, Bittrich S, Chao H, Chen L, Craig PA, Crichlow GV, Dalenberg K, Duarte JM, Dutta S, Fayazi M, Feng Z, Flatt JW, Ganesan SJ, Ghosh S, Goodsell DS, Green RK, Guranovic V, Henry J, Hudson BP, Khokhriakov I, Lawson CL, Liang Y, Lowe R, Peisach E, Persikova I, Piehl DW, Rose Y, Sali A, Segura J, Sekharan M, Shao C, Vallat B, Voigt M, Webb B, Westbrook JD, Whetstone S, Young JY, Zalevsky A, Zardecki C. PMID: 36281733; PMCID: PMC9667899.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Protein Data Bank: A Comprehensive Review of 3D Structure Holdings and Worldwide Utilization by Researchers, Educators, and Students. Biomolecules. 2022 10 04; 12(10).
Burley SK, Berman HM, Duarte JM, Feng Z, Flatt JW, Hudson BP, Lowe R, Peisach E, Piehl DW, Rose Y, Sali A, Sekharan M, Shao C, Vallat B, Voigt M, Westbrook JD, Young JY, Zardecki C. PMID: 36291635; PMCID: PMC9599165.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCells
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An intensity-based post-processing tool for 3D instance segmentation of organelles in soft X-ray tomograms. PLoS One. 2022; 17(9):e0269887.
Li A, Zhang S, Loconte V, Liu Y, Ekman A, Thompson GJ, Sali A, Stevens RC, White K, Singla J, Sun L. PMID: 36048824; PMCID: PMC9436087.
View in:
PubMed Mentions:
2 Fields:
Translation:
Cells
-
Quantitative, in situ visualization of intracellular insulin vesicles in pancreatic beta cells. Proc Natl Acad Sci U S A. 2022 08 09; 119(32):e2202695119.
Guo A, Zhang J, He B, Li A, Sun T, Li W, Wang J, Tai R, Liu Y, Qian Z, Fan J, Sali A, Stevens RC, Jiang H. PMID: 35921440; PMCID: PMC9371705.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Doublecortin engages the microtubule lattice through a cooperative binding mode involving its C-terminal domain. Elife. 2022 04 29; 11.
Rafiei A, Cruz Tetlalmatzi S, Edrington CH, Lee L, Crowder DA, Saltzberg DJ, Sali A, Brouhard G, Schriemer DC. PMID: 35485925; PMCID: PMC9122500.
View in:
PubMed Mentions:
2 Fields:
Translation:
Cells
-
Integrative structure determination of histones H3 and H4 using genetic interactions. FEBS J. 2023 05; 290(10):2565-2575.
Echeverria I, Braberg H, Krogan NJ, Sali A. PMID: 35298864; PMCID: PMC9481981.
View in:
PubMed Mentions:
1 Fields:
Translation:
Animals
-
The YΦ motif defines the structure-activity relationships of human 20S proteasome activators. Nat Commun. 2022 03 09; 13(1):1226.
Opoku-Nsiah KA, de la Pena AH, Williams SK, Chopra N, Sali A, Lander GC, Gestwicki JE. PMID: 35264557; PMCID: PMC8907193.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Soft X-ray tomography to map and quantify organelle interactions at the mesoscale. Structure. 2022 04 07; 30(4):510-521.e3.
Loconte V, Singla J, Li A, Chen JH, Ekman A, McDermott G, Sali A, Le Gros M, White KL, Larabell CA. PMID: 35148829; PMCID: PMC9013509.
View in:
PubMed Mentions:
11 Fields:
Translation:
Cells
-
Integration of software tools for integrative modeling of biomolecular systems. J Struct Biol. 2022 03; 214(1):107841.
Hancock M, Peulen TO, Webb B, Poon B, Fraser JS, Adams P, Sali A. PMID: 35149213; PMCID: PMC9278553.
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PubMed Mentions:
5 Fields:
-
Soluble TREM2 inhibits secondary nucleation of Aβ fibrillization and enhances cellular uptake of fibrillar Aβ. Proc Natl Acad Sci U S A. 2022 02 01; 119(5).
Belsare KD, Wu H, Mondal D, Bond A, Castillo E, Jin J, Jo H, Roush AE, Pilla KB, Sali A, Condello C, DeGrado WF. PMID: 35082148; PMCID: PMC8812518.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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From systems to structure - using genetic data to model protein structures. Nat Rev Genet. 2022 06; 23(6):342-354.
Braberg H, Echeverria I, Kaake RM, Sali A, Krogan NJ. PMID: 35013567; PMCID: PMC8744059.
View in:
PubMed Mentions:
11 Fields:
-
Comprehensive structure and functional adaptations of the yeast nuclear pore complex. Cell. 2022 01 20; 185(2):361-378.e25.
Akey CW, Singh D, Ouch C, Echeverria I, Nudelman I, Varberg JM, Yu Z, Fang F, Shi Y, Wang J, Salzberg D, Song K, Xu C, Gumbart JC, Suslov S, Unruh J, Jaspersen SL, Chait BT, Sali A, Fernandez-Martinez J, Ludtke SJ, Villa E, Rout MP. PMID: 34982960; PMCID: PMC8928745.
View in:
PubMed Mentions:
65 Fields:
Translation:
AnimalsCells
-
Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape. Elife. 2021 12 07; 10.
Mast FD, Fridy PC, Ketaren NE, Wang J, Jacobs EY, Olivier JP, Sanyal T, Molloy KR, Schmidt F, Rutkowska M, Weisblum Y, Rich LM, Vanderwall ER, Dambrauskas N, Vigdorovich V, Keegan S, Jiler JB, Stein ME, Olinares PDB, Herlands L, Hatziioannou T, Sather DN, Debley JS, Fenyö D, Sali A, Bieniasz PD, Aitchison JD, Chait BT, Rout MP. PMID: 34874007; PMCID: PMC8651292.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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New system for archiving integrative structures. Acta Crystallogr D Struct Biol. 2021 Dec 01; 77(Pt 12):1486-1496.
Vallat B, Webb B, Fayazi M, Voinea S, Tangmunarunkit H, Ganesan SJ, Lawson CL, Westbrook JD, Kesselman C, Sali A, Berman HM. PMID: 34866606; PMCID: PMC8647179.
View in:
PubMed Mentions:
18 Translation:
Cells
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Reversible phosphorylation of cyclin T1 promotes assembly and stability of P-TEFb. Elife. 2021 11 25; 10.
Huang F, Nguyen TT, Echeverria I, Rakesh R, Cary DC, Paculova H, Sali A, Weiss A, Peterlin BM, Fujinaga K. PMID: 34821217; PMCID: PMC8648303.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
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RCSB Protein Data Bank: Celebrating 50 years of the PDB with new tools for understanding and visualizing biological macromolecules in 3D. Protein Sci. 2022 01; 31(1):187-208.
Burley SK, Bhikadiya C, Bi C, Bittrich S, Chen L, Crichlow GV, Duarte JM, Dutta S, Fayazi M, Feng Z, Flatt JW, Ganesan SJ, Goodsell DS, Ghosh S, Kramer Green R, Guranovic V, Henry J, Hudson BP, Lawson CL, Liang Y, Lowe R, Peisach E, Persikova I, Piehl DW, Rose Y, Sali A, Segura J, Sekharan M, Shao C, Vallat B, Voigt M, Westbrook JD, Whetstone S, Young JY, Zardecki C. PMID: 34676613; PMCID: PMC8740825.
View in:
PubMed Mentions:
54 Fields:
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Bayesian metamodeling of complex biological systems across varying representations. Proc Natl Acad Sci U S A. 2021 08 31; 118(35).
Raveh B, Sun L, White KL, Sanyal T, Tempkin J, Zheng D, Bharath K, Singla J, Wang C, Zhao J, Li A, Graham NA, Kesselman C, Stevens RC, Sali A. PMID: 34453000; PMCID: PMC8536362.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
IMProv: A Resource for Cross-link-Driven Structure Modeling that Accommodates Protein Dynamics. Mol Cell Proteomics. 2021; 20:100139.
Ziemianowicz DS, Saltzberg D, Pells T, Crowder DA, Schräder C, Hepburn M, Sali A, Schriemer DC. PMID: 34418567; PMCID: PMC8452774.
View in:
PubMed Mentions:
4 Fields:
Translation:
Cells
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Characterization of an A3G-VifHIV-1-CRL5-CBFβ Structure Using a Cross-linking Mass Spectrometry Pipeline for Integrative Modeling of Host-Pathogen Complexes. Mol Cell Proteomics. 2021; 20:100132.
Kaake RM, Echeverria I, Kim SJ, Von Dollen J, Chesarino NM, Feng Y, Yu C, Ta H, Chelico L, Huang L, Gross J, Sali A, Krogan NJ. PMID: 34389466; PMCID: PMC8459920.
View in:
PubMed Mentions:
6 Fields:
-
The EBF1-PDGFRB T681I mutation is highly resistant to imatinib and dasatinib in vitro and detectable in clinical samples prior to treatment. Haematologica. 2021 08 01; 106(8):2242-2245.
Tran TH, Nguyen JV, Stecula A, Akutagawa J, Moorman AV, Braun BS, Sali A, Mullighan CG, Shah NP, Dai Y, Devidas M, Roberts KG, Smith CC, Loh ML. PMID: 33626861; PMCID: PMC8327742.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Integrative analysis reveals unique structural and functional features of the Smc5/6 complex. Proc Natl Acad Sci U S A. 2021 05 11; 118(19).
Yu Y, Li S, Ser Z, Sanyal T, Choi K, Wan B, Kuang H, Sali A, Kentsis A, Patel DJ, Zhao X. PMID: 33941673; PMCID: PMC8126833.
View in:
PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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CM1-driven assembly and activation of yeast γ-tubulin small complex underlies microtubule nucleation. Elife. 2021 05 05; 10.
Brilot AF, Lyon AS, Zelter A, Viswanath S, Maxwell A, MacCoss MJ, Muller EG, Sali A, Davis TN, Agard DA. PMID: 33949948; PMCID: PMC8099430.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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From integrative structural biology to cell biology. J Biol Chem. 2021 Jan-Jun; 296:100743.
Sali A. PMID: 33957123; PMCID: PMC8203844.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansAnimals
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Nanobody Repertoires for Exposing Vulnerabilities of SARS-CoV-2. bioRxiv. 2021 Apr 10.
Mast FD, Fridy PC, Ketaren NE, Wang J, Jacobs EY, Olivier JP, Sanyal T, Molloy KR, Schmidt F, Rutkowska M, Weisblum Y, Rich LM, Vanderwall ER, Dambrauskas N, Vigdorovich V, Keegan S, Jiler JB, Stein ME, Olinares PDB, Hatziioannou T, Sather DN, Debley JS, Fenyö D, Sali A, Bieniasz PD, Aitchison JD, Chait BT, Rout MP. PMID: 33851164; PMCID: PMC8043454.
View in:
PubMed Mentions:
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Global Protease Activity Profiling Identifies HER2-Driven Proteolysis in Breast Cancer. ACS Chem Biol. 2021 04 16; 16(4):712-723.
Salcedo EC, Winter MB, Khuri N, Knudsen GM, Sali A, Craik CS. PMID: 33765766.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
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RCSB Protein Data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences. Nucleic Acids Res. 2021 01 08; 49(D1):D437-D451.
Burley SK, Bhikadiya C, Bi C, Bittrich S, Chen L, Crichlow GV, Christie CH, Dalenberg K, Di Costanzo L, Duarte JM, Dutta S, Feng Z, Ganesan S, Goodsell DS, Ghosh S, Green RK, Guranovic V, Guzenko D, Hudson BP, Lawson CL, Liang Y, Lowe R, Namkoong H, Peisach E, Persikova I, Randle C, Rose A, Rose Y, Sali A, Segura J, Sekharan M, Shao C, Tao YP, Voigt M, Westbrook JD, Young JY, Zardecki C, Zhuravleva M. PMID: 33211854; PMCID: PMC7779003.
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PubMed Mentions:
536 Fields:
Translation:
HumansCellsPHPublic Health
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The active DNA-PK holoenzyme occupies a tensed state in a staggered synaptic complex. Structure. 2021 05 06; 29(5):467-478.e6.
Hepburn M, Saltzberg DJ, Lee L, Fang S, Atkinson C, Strynadka NCJ, Sali A, Lees-Miller SP, Schriemer DC. PMID: 33412091; PMCID: PMC8675206.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Protein Structure Modeling with MODELLER. Methods Mol Biol. 2021; 2199:239-255.
Webb B, Sali A. PMID: 33125654.
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PubMed Mentions:
60 Fields:
Translation:
Cells
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Genetic interaction mapping informs integrative structure determination of protein complexes. Science. 2020 12 11; 370(6522).
Braberg H, Echeverria I, Bohn S, Cimermancic P, Shiver A, Alexander R, Xu J, Shales M, Dronamraju R, Jiang S, Dwivedi G, Bogdanoff D, Chaung KK, Hüttenhain R, Wang S, Mavor D, Pellarin R, Schneidman D, Bader JS, Fraser JS, Morris J, Haber JE, Strahl BD, Gross CA, Dai J, Boeke JD, Sali A, Krogan NJ. PMID: 33303586; PMCID: PMC7946025.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Visualizing subcellular rearrangements in intact β cells using soft x-ray tomography. Sci Adv. 2020 12; 6(50).
White KL, Singla J, Loconte V, Chen JH, Ekman A, Sun L, Zhang X, Francis JP, Li A, Lin W, Tseng K, McDermott G, Alber F, Sali A, Larabell C, Stevens RC. PMID: 33298443; PMCID: PMC7725475.
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PubMed Mentions:
18 Fields:
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Using Integrative Modeling Platform to compute, validate, and archive a model of a protein complex structure. Protein Sci. 2021 01; 30(1):250-261.
Saltzberg DJ, Viswanath S, Echeverria I, Chemmama IE, Webb B, Sali A. PMID: 33166013; PMCID: PMC7737781.
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PubMed Mentions:
27 Fields:
Translation:
Cells
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Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science. 2020 12 04; 370(6521).
Gordon DE, Hiatt J, Bouhaddou M, Rezelj VV, Ulferts S, Braberg H, Jureka AS, Obernier K, Guo JZ, Batra J, Kaake RM, Weckstein AR, Owens TW, Gupta M, Pourmal S, Titus EW, Cakir M, Soucheray M, McGregor M, Cakir Z, Jang G, O'Meara MJ, Tummino TA, Zhang Z, Foussard H, Rojc A, Zhou Y, Kuchenov D, Hüttenhain R, Xu J, Eckhardt M, Swaney DL, Fabius JM, Ummadi M, Tutuncuoglu B, Rathore U, Modak M, Haas P, Haas KM, Naing ZZC, Pulido EH, Shi Y, Barrio-Hernandez I, Memon D, Petsalaki E, Dunham A, Marrero MC, Burke D, Koh C, Vallet T, Silvas JA, Azumaya CM, Billesbølle C, Brilot AF, Campbell MG, Diallo A, Dickinson MS, Diwanji D, Herrera N, Hoppe N, Kratochvil HT, Liu Y, Merz GE, Moritz M, Nguyen HC, Nowotny C, Puchades C, Rizo AN, Schulze-Gahmen U, Smith AM, Sun M, Young ID, Zhao J, Asarnow D, Biel J, Bowen A, Braxton JR, Chen J, Chio CM, Chio US, Deshpande I, Doan L, Faust B, Flores S, Jin M, Kim K, Lam VL, Li F, Li J, Li YL, Li Y, Liu X, Lo M, Lopez KE, Melo AA, Moss FR, Nguyen P, Paulino J, Pawar KI, Peters JK, Pospiech TH, Safari M, Sangwan S, Schaefer K, Thomas PV, Thwin AC, Trenker R, Tse E, Tsui TKM, Wang F, Whitis N, Yu Z, Zhang K, Zhang Y, Zhou F, Saltzberg D, QCRG Structural Biology Consortium, Hodder AJ, Shun-Shion AS, Williams DM, White KM, Rosales R, Kehrer T, Miorin L, Moreno E, Patel AH, Rihn S, Khalid MM, Vallejo-Gracia A, Fozouni P, Simoneau CR, Roth TL, Wu D, Karim MA, Ghoussaini M, Dunham I, Berardi F, Weigang S, Chazal M, Park J, Logue J, McGrath M, Weston S, Haupt R, Hastie CJ, Elliott M, Brown F, Burness KA, Reid E, Dorward M, Johnson C, Wilkinson SG, Geyer A, Giesel DM, Baillie C, Raggett S, Leech H, Toth R, Goodman N, Keough KC, Lind AL, Zoonomia Consortium, Klesh RJ, Hemphill KR, Carlson-Stevermer J, Oki J, Holden K, Maures T, Pollard KS, Sali A, Agard DA, Cheng Y, Fraser JS, Frost A, Jura N, Kortemme T, Manglik A, Southworth DR, Stroud RM, Alessi DR, Davies P, Frieman MB, Ideker T, Abate C, Jouvenet N, Kochs G, Shoichet B, Ott M, Palmarini M, et al. PMID: 33060197; PMCID: PMC7808408.
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PubMed Mentions:
382 Fields:
Translation:
HumansCells
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Toward Increased Reliability, Transparency, and Accessibility in Cross-linking Mass Spectrometry. Structure. 2020 11 03; 28(11):1259-1268.
Leitner A, Bonvin AMJJ, Borchers CH, Chalkley RJ, Chamot-Rooke J, Combe CW, Cox J, Dong MQ, Fischer L, Götze M, Gozzo FC, Heck AJR, Hoopmann MR, Huang L, Ishihama Y, Jones AR, Kalisman N, Kohlbacher O, Mechtler K, Moritz RL, Netz E, Novak P, Petrotchenko E, Sali A, Scheltema RA, Schmidt C, Schriemer D, Sinz A, Sobott F, Stengel F, Thalassinos K, Urlaub H, Viner R, Vizcaíno JA, Wilkins MR, Rappsilber J. PMID: 33065067.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality. J Cell Biol. 2020 10 05; 219(10).
Mast FD, Navare AT, van der Sloot AM, Coulombe-Huntington J, Rout MP, Baliga NS, Kaushansky A, Chait BT, Aderem A, Rice CM, Sali A, Tyers M, Aitchison JD. PMID: 32785687; PMCID: PMC7659715.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Structural basis of CD4 downregulation by HIV-1 Nef. Nat Struct Mol Biol. 2020 09; 27(9):822-828.
Kwon Y, Kaake RM, Echeverria I, Suarez M, Karimian Shamsabadi M, Stoneham C, Ramirez PW, Kress J, Singh R, Sali A, Krogan N, Guatelli J, Jia X. PMID: 32719457; PMCID: PMC7483821.
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PubMed Mentions:
30 Fields:
Translation:
HumansCells
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Integrative structure and function of the yeast exocyst complex. Protein Sci. 2020 06; 29(6):1486-1501.
Ganesan SJ, Feyder MJ, Chemmama IE, Fang F, Rout MP, Chait BT, Shi Y, Munson M, Sali A. PMID: 32239688; PMCID: PMC7255525.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature. 2020 07; 583(7816):459-468.
Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, White KM, O'Meara MJ, Rezelj VV, Guo JZ, Swaney DL, Tummino TA, Hüttenhain R, Kaake RM, Richards AL, Tutuncuoglu B, Foussard H, Batra J, Haas K, Modak M, Kim M, Haas P, Polacco BJ, Braberg H, Fabius JM, Eckhardt M, Soucheray M, Bennett MJ, Cakir M, McGregor MJ, Li Q, Meyer B, Roesch F, Vallet T, Mac Kain A, Miorin L, Moreno E, Naing ZZC, Zhou Y, Peng S, Shi Y, Zhang Z, Shen W, Kirby IT, Melnyk JE, Chorba JS, Lou K, Dai SA, Barrio-Hernandez I, Memon D, Hernandez-Armenta C, Lyu J, Mathy CJP, Perica T, Pilla KB, Ganesan SJ, Saltzberg DJ, Rakesh R, Liu X, Rosenthal SB, Calviello L, Venkataramanan S, Liboy-Lugo J, Lin Y, Huang XP, Liu Y, Wankowicz SA, Bohn M, Safari M, Ugur FS, Koh C, Savar NS, Tran QD, Shengjuler D, Fletcher SJ, O'Neal MC, Cai Y, Chang JCJ, Broadhurst DJ, Klippsten S, Sharp PP, Wenzell NA, Kuzuoglu-Ozturk D, Wang HY, Trenker R, Young JM, Cavero DA, Hiatt J, Roth TL, Rathore U, Subramanian A, Noack J, Hubert M, Stroud RM, Frankel AD, Rosenberg OS, Verba KA, Agard DA, Ott M, Emerman M, Jura N, von Zastrow M, Verdin E, Ashworth A, Schwartz O, d'Enfert C, Mukherjee S, Jacobson M, Malik HS, Fujimori DG, Ideker T, Craik CS, Floor SN, Fraser JS, Gross JD, Sali A, Roth BL, Ruggero D, Taunton J, Kortemme T, Beltrao P, Vignuzzi M, García-Sastre A, Shokat KM, Shoichet BK, Krogan NJ. PMID: 32353859; PMCID: PMC7431030.
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A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing. bioRxiv. 2020 Mar 27.
Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, O'Meara MJ, Guo JZ, Swaney DL, Tummino TA, Huettenhain R, Kaake RM, Richards AL, Tutuncuoglu B, Foussard H, Batra J, Haas K, Modak M, Kim M, Haas P, Polacco BJ, Braberg H, Fabius JM, Eckhardt M, Soucheray M, Bennett MJ, Cakir M, McGregor MJ, Li Q, Naing ZZC, Zhou Y, Peng S, Kirby IT, Melnyk JE, Chorba JS, Lou K, Dai SA, Shen W, Shi Y, Zhang Z, Barrio-Hernandez I, Memon D, Hernandez-Armenta C, Mathy CJP, Perica T, Pilla KB, Ganesan SJ, Saltzberg DJ, Ramachandran R, Liu X, Rosenthal SB, Calviello L, Venkataramanan S, Liboy-Lugo J, Lin Y, Wankowicz SA, Bohn M, Sharp PP, Trenker R, Young JM, Cavero DA, Hiatt J, Roth TL, Rathore U, Subramanian A, Noack J, Hubert M, Roesch F, Vallet T, Meyer B, White KM, Miorin L, Rosenberg OS, Verba KA, Agard D, Ott M, Emerman M, Ruggero D, García-Sastre A, Jura N, von Zastrow M, Taunton J, Ashworth A, Schwartz O, Vignuzzi M, d'Enfert C, Mukherjee S, Jacobson M, Malik HS, Fujimori DG, Ideker T, Craik CS, Floor S, Fraser JS, Gross J, Sali A, Kortemme T, Beltrao P, Shokat K, Shoichet BK, Krogan NJ. PMID: 32511329; PMCID: PMC7239059.
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PubMed Mentions:
6
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Structural dynamics of the human COP9 signalosome revealed by cross-linking mass spectrometry and integrative modeling. Proc Natl Acad Sci U S A. 2020 02 25; 117(8):4088-4098.
Gutierrez C, Chemmama IE, Mao H, Yu C, Echeverria I, Block SA, Rychnovsky SD, Zheng N, Sali A, Huang L. PMID: 32034103; PMCID: PMC7049115.
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PubMed Mentions:
35 Fields:
Translation:
HumansCells
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Federating Structural Models and Data: Outcomes from A Workshop on Archiving Integrative Structures. Structure. 2019 12 03; 27(12):1745-1759.
Berman HM, Adams PD, Bonvin AA, Burley SK, Carragher B, Chiu W, DiMaio F, Ferrin TE, Gabanyi MJ, Goddard TD, Griffin PR, Haas J, Hanke CA, Hoch JC, Hummer G, Kurisu G, Lawson CL, Leitner A, Markley JL, Meiler J, Montelione GT, Phillips GN, Prisner T, Rappsilber J, Schriemer DC, Schwede T, Seidel CAM, Strutzenberg TS, Svergun DI, Tajkhorshid E, Trewhella J, Vallat B, Velankar S, Vuister GW, Webb B, Westbrook JD, White KL, Sali A. PMID: 31780431; PMCID: PMC7108332.
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PubMed Mentions:
19 Fields:
Translation:
Cells
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SSEThread: Integrative threading of the DNA-PKcs sequence based on data from chemical cross-linking and hydrogen deuterium exchange. Prog Biophys Mol Biol. 2019 10; 147:92-102.
Saltzberg DJ, Hepburn M, Pilla KB, Schriemer DC, Lees-Miller SP, Blundell TL, Sali A. PMID: 31570166; PMCID: PMC6903780.
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PubMed Mentions:
5 Fields:
Translation:
Cells
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Archiving and disseminating integrative structure models. J Biomol NMR. 2019 Jul; 73(6-7):385-398.
Vallat B, Webb B, Westbrook J, Sali A, Berman HM. PMID: 31278630; PMCID: PMC6692293.
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PubMed Mentions:
12 Fields:
Translation:
Cells
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Principles for Integrative Structural Biology Studies. Cell. 2019 05 30; 177(6):1384-1403.
Rout MP, Sali A. PMID: 31150619; PMCID: PMC6810593.
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PubMed Mentions:
121 Fields:
Translation:
HumansAnimalsCells
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Glutamine Side Chain 13C═18O as a Nonperturbative IR Probe of Amyloid Fibril Hydration and Assembly. J Am Chem Soc. 2019 05 08; 141(18):7320-7326.
Wu H, Saltzberg DJ, Kratochvil HT, Jo H, Sali A, DeGrado WF. PMID: 30998340; PMCID: PMC6800148.
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PubMed Mentions:
6 Fields:
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Importin-9 wraps around the H2A-H2B core to act as nuclear importer and histone chaperone. Elife. 2019 03 11; 8.
Padavannil A, Sarkar P, Kim SJ, Cagatay T, Jiou J, Brautigam CA, Tomchick DR, Sali A, D'Arcy S, Chook YM. PMID: 30855230; PMCID: PMC6453568.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Modeling Biological Complexes Using Integrative Modeling Platform. Methods Mol Biol. 2019; 2022:353-377.
Saltzberg D, Greenberg CH, Viswanath S, Chemmama I, Webb B, Pellarin R, Echeverria I, Sali A. PMID: 31396911.
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PubMed Mentions:
20 Fields:
Translation:
Cells
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Optimizing model representation for integrative structure determination of macromolecular assemblies. Proc Natl Acad Sci U S A. 2019 01 08; 116(2):540-545.
Viswanath S, Sali A. PMID: 30587581; PMCID: PMC6329962.
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PubMed Mentions:
12 Fields:
Translation:
Cells
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Predicting CD4 T-cell epitopes based on antigen cleavage, MHCII presentation, and TCR recognition. PLoS One. 2018; 13(11):e0206654.
Schneidman-Duhovny D, Khuri N, Dong GQ, Winter MB, Shifrut E, Friedman N, Craik CS, Pratt KP, Paz P, Aswad F, Sali A. PMID: 30399156; PMCID: PMC6219782.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Bayesian Weighing of Electron Cryo-Microscopy Data for Integrative Structural Modeling. Structure. 2019 01 02; 27(1):175-188.e6.
Bonomi M, Hanot S, Greenberg CH, Sali A, Nilges M, Vendruscolo M, Pellarin R. PMID: 30393052; PMCID: PMC6779587.
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PubMed Mentions:
25 Fields:
Translation:
Cells
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Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1. Nat Struct Mol Biol. 2018 09; 25(9):859-867.
Jishage M, Yu X, Shi Y, Ganesan SJ, Chen WY, Sali A, Chait BT, Asturias FJ, Roeder RG. PMID: 30190596; PMCID: PMC6298426.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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Atlas of the Radical SAM Superfamily: Divergent Evolution of Function Using a "Plug and Play" Domain. Methods Enzymol. 2018; 606:1-71.
Holliday GL, Akiva E, Meng EC, Brown SD, Calhoun S, Pieper U, Sali A, Booker SJ, Babbitt PC. PMID: 30097089; PMCID: PMC6445391.
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PubMed Mentions:
71 Fields:
Translation:
Cells
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Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell. 2018 04 19; 173(3):693-705.e22.
Yoshizawa T, Ali R, Jiou J, Fung HYJ, Burke KA, Kim SJ, Lin Y, Peeples WB, Saltzberg D, Soniat M, Baumhardt JM, Oldenbourg R, Sali A, Fawzi NL, Rosen MK, Chook YM. PMID: 29677513; PMCID: PMC6234985.
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PubMed Mentions:
156 Fields:
Translation:
HumansCells
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Development of a Prototype System for Archiving Integrative/Hybrid Structure Models of Biological Macromolecules. Structure. 2018 06 05; 26(6):894-904.e2.
Vallat B, Webb B, Westbrook JD, Sali A, Berman HM. PMID: 29657133; PMCID: PMC5990459.
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PubMed Mentions:
49 Fields:
Translation:
Cells
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Opportunities and Challenges in Building a Spatiotemporal Multi-scale Model of the Human Pancreatic β Cell. Cell. 2018 03 22; 173(1):11-19.
Singla J, McClary KM, White KL, Alber F, Sali A, Stevens RC. PMID: 29570991; PMCID: PMC6014618.
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PubMed Mentions:
33 Fields:
Translation:
HumansCells
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Integrative structure and functional anatomy of a nuclear pore complex. Nature. 2018 03 22; 555(7697):475-482.
Kim SJ, Fernandez-Martinez J, Nudelman I, Shi Y, Zhang W, Raveh B, Herricks T, Slaughter BD, Hogan JA, Upla P, Chemmama IE, Pellarin R, Echeverria I, Shivaraju M, Chaudhury AS, Wang J, Williams R, Unruh JR, Greenberg CH, Jacobs EY, Yu Z, de la Cruz MJ, Mironska R, Stokes DL, Aitchison JD, Jarrold MF, Gerton JL, Ludtke SJ, Akey CW, Chait BT, Sali A, Rout MP. PMID: 29539637; PMCID: PMC6022767.
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PubMed Mentions:
239 Fields:
Translation:
AnimalsCells
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Proteome-wide mapping of immune features onto Plasmodium protein three-dimensional structures. Sci Rep. 2018 03 12; 8(1):4355.
Guy AJ, Irani V, Beeson JG, Webb B, Sali A, Richards JS, Ramsland PA. PMID: 29531293; PMCID: PMC5847524.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Prediction of enzymatic pathways by integrative pathway mapping. Elife. 2018 01 29; 7.
Calhoun S, Korczynska M, Wichelecki DJ, San Francisco B, Zhao S, Rodionov DA, Vetting MW, Al-Obaidi NF, Lin H, O'Meara MJ, Scott DA, Morris JH, Russel D, Almo SC, Osterman AL, Gerlt JA, Jacobson MP, Shoichet BK, Sali A. PMID: 29377793; PMCID: PMC5788505.
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PubMed Mentions:
15 Fields:
Translation:
Cells
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Assessing Exhaustiveness of Stochastic Sampling for Integrative Modeling of Macromolecular Structures. Biophys J. 2017 Dec 05; 113(11):2344-2353.
Viswanath S, Chemmama IE, Cimermancic P, Sali A. PMID: 29211988; PMCID: PMC5768525.
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PubMed Mentions:
49 Fields:
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Immunoproteasome functions explained by divergence in cleavage specificity and regulation. Elife. 2017 11 28; 6.
Winter MB, La Greca F, Arastu-Kapur S, Caiazza F, Cimermancic P, Buchholz TJ, Anderl JL, Ravalin M, Bohn MF, Sali A, O'Donoghue AJ, Craik CS. PMID: 29182146; PMCID: PMC5705213.
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PubMed Mentions:
37 Fields:
Translation:
HumansCells
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Integrative structure modeling with the Integrative Modeling Platform. Protein Sci. 2018 01; 27(1):245-258.
Webb B, Viswanath S, Bonomi M, Pellarin R, Greenberg CH, Saltzberg D, Sali A. PMID: 28960548; PMCID: PMC5734277.
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PubMed Mentions:
52 Fields:
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Cross-activating c-Met/β1 integrin complex drives metastasis and invasive resistance in cancer. Proc Natl Acad Sci U S A. 2017 10 10; 114(41):E8685-E8694.
Jahangiri A, Nguyen A, Chandra A, Sidorov MK, Yagnik G, Rick J, Han SW, Chen W, Flanigan PM, Schneidman-Duhovny D, Mascharak S, De Lay M, Imber B, Park CC, Matsumoto K, Lu K, Bergers G, Sali A, Weiss WA, Aghi MK. PMID: 28973887; PMCID: PMC5642678.
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PubMed Mentions:
47 Fields:
Translation:
HumansAnimalsCells
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PDB-Dev: a Prototype System for Depositing Integrative/Hybrid Structural Models. Structure. 2017 09 05; 25(9):1317-1318.
Burley SK, Kurisu G, Markley JL, Nakamura H, Velankar S, Berman HM, Sali A, Schwede T, Trewhella J. PMID: 28877501; PMCID: PMC5821105.
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PubMed Mentions:
47 Fields:
Translation:
Cells
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2017 publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution: an update. Acta Crystallogr D Struct Biol. 2017 Sep 01; 73(Pt 9):710-728.
Trewhella J, Duff AP, Durand D, Gabel F, Guss JM, Hendrickson WA, Hura GL, Jacques DA, Kirby NM, Kwan AH, Pérez J, Pollack L, Ryan TM, Sali A, Schneidman-Duhovny D, Schwede T, Svergun DI, Sugiyama M, Tainer JA, Vachette P, Westbrook J, Whitten AE. PMID: 28876235; PMCID: PMC5586245.
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PubMed Mentions:
126 Translation:
HumansAnimalsCells
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The molecular architecture of the yeast spindle pole body core determined by Bayesian integrative modeling. Mol Biol Cell. 2017 Nov 07; 28(23):3298-3314.
Viswanath S, Bonomi M, Kim SJ, Klenchin VA, Taylor KC, Yabut KC, Umbreit NT, Van Epps HA, Meehl J, Jones MH, Russel D, Velazquez-Muriel JA, Winey M, Rayment I, Davis TN, Sali A, Muller EG. PMID: 28814505; PMCID: PMC5687031.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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The proteasome-interacting Ecm29 protein disassembles the 26S proteasome in response to oxidative stress. J Biol Chem. 2017 09 29; 292(39):16310-16320.
Wang X, Chemmama IE, Yu C, Huszagh A, Xu Y, Viner R, Block SA, Cimermancic P, Rychnovsky SD, Ye Y, Sali A, Huang L. PMID: 28821611; PMCID: PMC5625060.
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PubMed Mentions:
49 Fields:
Translation:
HumansCells
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Human Concentrative Nucleoside Transporter 3 (hCNT3, SLC28A3) Forms a Cyclic Homotrimer. Biochemistry. 2017 07 11; 56(27):3475-3483.
Stecula A, Schlessinger A, Giacomini KM, Sali A. PMID: 28661652; PMCID: PMC6917504.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Computational Discovery and Experimental Validation of Inhibitors of the Human Intestinal Transporter OATP2B1. J Chem Inf Model. 2017 06 26; 57(6):1402-1413.
Khuri N, Zur AA, Wittwer MB, Lin L, Yee SW, Sali A, Giacomini KM. PMID: 28562037.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Regulation of Rvb1/Rvb2 by a Domain within the INO80 Chromatin Remodeling Complex Implicates the Yeast Rvbs as Protein Assembly Chaperones. Cell Rep. 2017 06 06; 19(10):2033-2044.
Zhou CY, Stoddard CI, Johnston JB, Trnka MJ, Echeverria I, Palovcak E, Sali A, Burlingame AL, Cheng Y, Narlikar GJ. PMID: 28591576; PMCID: PMC5564220.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Reconstruction of 3D structures of MET antibodies from electron microscopy 2D class averages. PLoS One. 2017; 12(4):e0175758.
Chen Q, Vieth M, Timm DE, Humblet C, Schneidman-Duhovny D, Chemmama IE, Sali A, Zeng W, Lu J, Liu L. PMID: 28406969; PMCID: PMC5391116.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1). J Med Chem. 2017 04 13; 60(7):2685-2696.
Chen EC, Khuri N, Liang X, Stecula A, Chien HC, Yee SW, Huang Y, Sali A, Giacomini KM. PMID: 28230985.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome. Mol Cell Proteomics. 2017 05; 16(5):840-854.
Wang X, Cimermancic P, Yu C, Schweitzer A, Chopra N, Engel JL, Greenberg C, Huszagh AS, Beck F, Sakata E, Yang Y, Novitsky EJ, Leitner A, Nanni P, Kahraman A, Guo X, Dixon JE, Rychnovsky SD, Aebersold R, Baumeister W, Sali A, Huang L. PMID: 28292943; PMCID: PMC5417825.
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PubMed Mentions:
51 Fields:
Translation:
HumansCells
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Lineage-specific proteins essential for endocytosis in trypanosomes. J Cell Sci. 2017 04 15; 130(8):1379-1392.
Manna PT, Obado SO, Boehm C, Gadelha C, Sali A, Chait BT, Rout MP, Field MC. PMID: 28232524; PMCID: PMC5399782.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimals
-
Molecular Architecture of the Major Membrane Ring Component of the Nuclear Pore Complex. Structure. 2017 03 07; 25(3):434-445.
Upla P, Kim SJ, Sampathkumar P, Dutta K, Cahill SM, Chemmama IE, Williams R, Bonanno JB, Rice WJ, Stokes DL, Cowburn D, Almo SC, Sali A, Rout MP, Fernandez-Martinez J. PMID: 28162953; PMCID: PMC5342941.
View in:
PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
-
Protein Structure Modeling with MODELLER. Methods Mol Biol. 2017; 1654:39-54.
Webb B, Sali A. PMID: 28986782.
View in:
PubMed Mentions:
205 Fields:
Translation:
Cells
-
A Residue-Resolved Bayesian Approach to Quantitative Interpretation of Hydrogen-Deuterium Exchange from Mass Spectrometry: Application to Characterizing Protein-Ligand Interactions. J Phys Chem B. 2017 04 20; 121(15):3493-3501.
Saltzberg DJ, Broughton HB, Pellarin R, Chalmers MJ, Espada A, Dodge JA, Pascal BD, Griffin PR, Humblet C, Sali A. PMID: 27807976; PMCID: PMC5693600.
View in:
PubMed Mentions:
26 Fields:
Translation:
Cells
-
Editorial overview: Biophysical and molecular biological methods. Curr Opin Struct Biol. 2016 10; 40:ix-xi.
Fromme P, Sali A. PMID: 27908508.
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PubMed Mentions: Fields:
-
Clustering of disulfide-rich peptides provides scaffolds for hit discovery by phage display: application to interleukin-23. BMC Bioinformatics. 2016 Nov 23; 17(1):481.
Barkan DT, Cheng XL, Celino H, Tran TT, Bhandari A, Craik CS, Sali A, Smythe ML. PMID: 27881076; PMCID: PMC5120537.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
-
Structure and Function of the Nuclear Pore Complex Cytoplasmic mRNA Export Platform. Cell. 2016 11 17; 167(5):1215-1228.e25.
Fernandez-Martinez J, Kim SJ, Shi Y, Upla P, Pellarin R, Gagnon M, Chemmama IE, Wang J, Nudelman I, Zhang W, Williams R, Rice WJ, Stokes DL, Zenklusen D, Chait BT, Sali A, Rout MP. PMID: 27839866; PMCID: PMC5130164.
View in:
PubMed Mentions:
86 Fields:
Translation:
AnimalsCells
-
Comparative Protein Structure Modeling Using MODELLER. Curr Protoc Protein Sci. 2016 Nov 01; 86:2.9.1-2.9.37.
Webb B, Sali A. PMID: 27801516.
View in:
PubMed Mentions:
268 Fields:
Translation:
AnimalsCells
-
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
-
Insights into HIV-1 proviral transcription from integrative structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex. Elife. 2016 10 12; 5.
Schulze-Gahmen U, Echeverria I, Stjepanovic G, Bai Y, Lu H, Schneidman-Duhovny D, Doudna JA, Zhou Q, Sali A, Hurley JH. PMID: 27731797; PMCID: PMC5072841.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCells
-
Simple rules for passive diffusion through the nuclear pore complex. J Cell Biol. 2016 Oct 10; 215(1):57-76.
Timney BL, Raveh B, Mironska R, Trivedi JM, Kim SJ, Russel D, Wente SR, Sali A, Rout MP. PMID: 27697925; PMCID: PMC5057280.
View in:
PubMed Mentions:
216 Fields:
Translation:
AnimalsCells
-
Comparative Protein Structure Modeling Using MODELLER. Curr Protoc Bioinformatics. 2016 06 20; 54:5.6.1-5.6.37.
Webb B, Sali A. PMID: 27322406; PMCID: PMC5031415.
View in:
PubMed Mentions:
1268 Fields:
Translation:
AnimalsCells
-
Prediction of homoprotein and heteroprotein complexes by protein docking and template-based modeling: A CASP-CAPRI experiment. Proteins. 2016 09; 84 Suppl 1:323-48.
Lensink MF, Velankar S, Kryshtafovych A, Huang SY, Schneidman-Duhovny D, Sali A, Segura J, Fernandez-Fuentes N, Viswanath S, Elber R, Grudinin S, Popov P, Neveu E, Lee H, Baek M, Park S, Heo L, Rie Lee G, Seok C, Qin S, Zhou HX, Ritchie DW, Maigret B, Devignes MD, Ghoorah A, Torchala M, Chaleil RA, Bates PA, Ben-Zeev E, Eisenstein M, Negi SS, Weng Z, Vreven T, Pierce BG, Borrman TM, Yu J, Ochsenbein F, Guerois R, Vangone A, Rodrigues JP, van Zundert G, Nellen M, Xue L, Karaca E, Melquiond AS, Visscher K, Kastritis PL, Bonvin AM, Xu X, Qiu L, Yan C, Li J, Ma Z, Cheng J, Zou X, Shen Y, Peterson LX, Kim HR, Roy A, Han X, Esquivel-Rodriguez J, Kihara D, Yu X, Bruce NJ, Fuller JC, Wade RC, Anishchenko I, Kundrotas PJ, Vakser IA, Imai K, Yamada K, Oda T, Nakamura T, Tomii K, Pallara C, Romero-Durana M, Jiménez-García B, Moal IH, Férnandez-Recio J, Joung JY, Kim JY, Joo K, Lee J, Kozakov D, Vajda S, Mottarella S, Hall DR, Beglov D, Mamonov A, Xia B, Bohnuud T, Del Carpio CA, Ichiishi E, Marze N, Kuroda D, Roy Burman SS, Gray JJ, Chermak E, Cavallo L, Oliva R, Tovchigrechko A, Wodak SJ. PMID: 27122118; PMCID: PMC5030136.
View in:
PubMed Mentions:
73 Fields:
Translation:
HumansCells
-
Structure of Complement C3(H2O) Revealed By Quantitative Cross-Linking/Mass Spectrometry And Modeling. Mol Cell Proteomics. 2016 08; 15(8):2730-43.
Chen ZA, Pellarin R, Fischer L, Sali A, Nilges M, Barlow PN, Rappsilber J. PMID: 27250206; PMCID: PMC4974347.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansCells
-
FoXS, FoXSDock and MultiFoXS: Single-state and multi-state structural modeling of proteins and their complexes based on SAXS profiles. Nucleic Acids Res. 2016 Jul 08; 44(W1):W424-9.
Schneidman-Duhovny D, Hammel M, Tainer JA, Sali A. PMID: 27151198; PMCID: PMC4987932.
View in:
PubMed Mentions:
251 Fields:
Translation:
Cells
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Slide-and-exchange mechanism for rapid and selective transport through the nuclear pore complex. Proc Natl Acad Sci U S A. 2016 May 03; 113(18):E2489-97.
Raveh B, Karp JM, Sparks S, Dutta K, Rout MP, Sali A, Cowburn D. PMID: 27091992; PMCID: PMC4983827.
View in:
PubMed Mentions:
53 Fields:
Translation:
Cells
-
A phosphotyrosine switch regulates organic cation transporters. Nat Commun. 2016 Mar 16; 7:10880.
Sprowl JA, Ong SS, Gibson AA, Hu S, Du G, Lin W, Li L, Bharill S, Ness RA, Stecula A, Offer SM, Diasio RB, Nies AT, Schwab M, Cavaletti G, Schlatter E, Ciarimboli G, Schellens JHM, Isacoff EY, Sali A, Chen T, Baker SD, Sparreboom A, Pabla N. PMID: 26979622; PMCID: PMC4799362.
View in:
PubMed Mentions:
56 Fields:
Translation:
HumansAnimalsCells
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Structure of γ-tubulin small complex based on a cryo-EM map, chemical cross-links, and a remotely related structure. J Struct Biol. 2016 06; 194(3):303-10.
Greenberg CH, Kollman J, Zelter A, Johnson R, MacCoss MJ, Davis TN, Agard DA, Sali A. PMID: 26968363; PMCID: PMC4866596.
View in:
PubMed Mentions:
10 Fields:
Translation:
Cells
-
CryptoSite: Expanding the Druggable Proteome by Characterization and Prediction of Cryptic Binding Sites. J Mol Biol. 2016 Feb 22; 428(4):709-719.
Cimermancic P, Weinkam P, Rettenmaier TJ, Bichmann L, Keedy DA, Woldeyes RA, Schneidman-Duhovny D, Demerdash ON, Mitchell JC, Wells JA, Fraser JS, Sali A. PMID: 26854760; PMCID: PMC4794384.
View in:
PubMed Mentions:
84 Fields:
Translation:
HumansCells
-
Novel TKI-resistant BCR-ABL1 gatekeeper residue mutations retain in vitro sensitivity to axitinib. Leukemia. 2016 06; 30(6):1405-9.
Lasater EA, Massi ES, Stecula A, Politi J, Tan SK, Smith CC, Gunthorpe M, Holmes JP, Chehab F, Sali A, Shah NP. PMID: 26511402.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
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Assembly and Molecular Architecture of the Phosphoinositide 3-Kinase p85α Homodimer. J Biol Chem. 2015 Dec 18; 290(51):30390-405.
LoPiccolo J, Kim SJ, Shi Y, Wu B, Wu H, Chait BT, Singer RH, Sali A, Brenowitz M, Bresnick AR, Backer JM. PMID: 26475863; PMCID: PMC4683262.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Small-Molecule Allosteric Modulators of the Protein Kinase PDK1 from Structure-Based Docking. J Med Chem. 2015 Oct 22; 58(20):8285-8291.
Rettenmaier TJ, Fan H, Karpiak J, Doak A, Sali A, Shoichet BK, Wells JA. PMID: 26443011; PMCID: PMC5099076.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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A strategy for dissecting the architectures of native macromolecular assemblies. Nat Methods. 2015 Dec; 12(12):1135-8.
Shi Y, Pellarin R, Fridy PC, Fernandez-Martinez J, Thompson MK, Li Y, Wang QJ, Sali A, Rout MP, Chait BT. PMID: 26436480; PMCID: PMC4803312.
View in:
PubMed Mentions:
81 Fields:
Translation:
AnimalsCells
-
Molecular architecture of the yeast Mediator complex. Elife. 2015 Sep 24; 4.
Robinson PJ, Trnka MJ, Pellarin R, Greenberg CH, Bushnell DA, Davis R, Burlingame AL, Sali A, Kornberg RD. PMID: 26402457; PMCID: PMC4631838.
View in:
PubMed Mentions:
89 Fields:
Translation:
Animals
-
Architecture of the Human and Yeast General Transcription and DNA Repair Factor TFIIH. Mol Cell. 2015 Sep 03; 59(5):794-806.
Luo J, Cimermancic P, Viswanath S, Ebmeier CC, Kim B, Dehecq M, Raman V, Greenberg CH, Pellarin R, Sali A, Taatjes DJ, Hahn S, Ranish J. PMID: 26340423; PMCID: PMC4560838.
View in:
PubMed Mentions:
62 Fields:
Translation:
HumansAnimalsCells
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Prediction of Functionally Important Phospho-Regulatory Events in Xenopus laevis Oocytes. PLoS Comput Biol. 2015 Aug; 11(8):e1004362.
Johnson JR, Santos SD, Johnson T, Pieper U, Strumillo M, Wagih O, Sali A, Krogan NJ, Beltrao P. PMID: 26312481; PMCID: PMC4552029.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
Structural Model of the Bilitranslocase Transmembrane Domain Supported by NMR and FRET Data. PLoS One. 2015; 10(8):e0135455.
Roy Choudhury A, Sikorska E, van den Boom J, Bayer P, Popenda L, Szutkowski K, Jurga S, Bonomi M, Sali A, Zhukov I, Passamonti S, Novic M. PMID: 26291722; PMCID: PMC4546402.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Prion Protein-Antibody Complexes Characterized by Chromatography-Coupled Small-Angle X-Ray Scattering. Biophys J. 2015 Aug 18; 109(4):793-805.
Carter L, Kim SJ, Schneidman-Duhovny D, Stöhr J, Poncet-Montange G, Weiss TM, Tsuruta H, Prusiner SB, Sali A. PMID: 26287631; PMCID: PMC4547163.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
-
FLT3 D835 mutations confer differential resistance to type II FLT3 inhibitors. Leukemia. 2015 Dec; 29(12):2390-2.
Smith CC, Lin K, Stecula A, Sali A, Shah NP. PMID: 26108694; PMCID: PMC4675689.
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PubMed Mentions:
94 Fields:
Translation:
HumansCells
-
Outcome of the First wwPDB Hybrid/Integrative Methods Task Force Workshop. Structure. 2015 Jul 07; 23(7):1156-67.
Sali A, Berman HM, Schwede T, Trewhella J, Kleywegt G, Burley SK, Markley J, Nakamura H, Adams P, Bonvin AM, Chiu W, Peraro MD, Di Maio F, Ferrin TE, Grünewald K, Gutmanas A, Henderson R, Hummer G, Iwasaki K, Johnson G, Lawson CL, Meiler J, Marti-Renom MA, Montelione GT, Nilges M, Nussinov R, Patwardhan A, Rappsilber J, Read RJ, Saibil H, Schröder GF, Schwieters CD, Seidel CA, Svergun D, Topf M, Ulrich EL, Velankar S, Westbrook JD. PMID: 26095030; PMCID: PMC4933300.
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PubMed Mentions:
96 Fields:
Translation:
HumansCells
-
Growing an editorial board for an ever expanding field. Structure. 2015 Apr 07; 23(4):605.
Lima CD, Sali A, Kostic M. PMID: 25862929.
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PubMed Mentions: Fields:
-
Scoring Large-Scale Affinity Purification Mass Spectrometry Datasets with MiST. Curr Protoc Bioinformatics. 2015 Mar 09; 49:8.19.1-8.19.16.
Verschueren E, Von Dollen J, Cimermancic P, Gulbahce N, Sali A, Krogan NJ. PMID: 25754993; PMCID: PMC4378866.
View in:
PubMed Mentions:
37 Fields:
-
Ring closure activates yeast γTuRC for species-specific microtubule nucleation. Nat Struct Mol Biol. 2015 Feb; 22(2):132-7.
Kollman JM, Greenberg CH, Li S, Moritz M, Zelter A, Fong KK, Fernandez JJ, Sali A, Kilmartin J, Davis TN, Agard DA. PMID: 25599398; PMCID: PMC4318760.
View in:
PubMed Mentions:
63 Fields:
Translation:
AnimalsCells
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Topological models of heteromeric protein assemblies from mass spectrometry: application to the yeast eIF3:eIF5 complex. Chem Biol. 2015 Jan 22; 22(1):117-28.
Politis A, Schmidt C, Tjioe E, Sandercock AM, Lasker K, Gordiyenko Y, Russel D, Sali A, Robinson CV. PMID: 25544043; PMCID: PMC4306531.
View in:
PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
-
A systematic computational analysis of biosynthetic gene cluster evolution: lessons for engineering biosynthesis. PLoS Comput Biol. 2014 Dec; 10(12):e1004016.
Medema MH, Cimermancic P, Sali A, Takano E, Fischbach MA. PMID: 25474254; PMCID: PMC4256081.
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PubMed Mentions:
87 Fields:
-
Molecular Architecture of the 40S⋅eIF1⋅eIF3 Translation Initiation Complex. Cell. 2014 Nov 20; 159(5):1227-1228.
Erzberger JP, Stengel F, Pellarin R, Zhang S, Schaefer T, Aylett CHS, Cimermancic P, Boehringer D, Sali A, Aebersold R, Ban N. PMID: 28898626; PMCID: PMC5628955.
View in:
PubMed Mentions:
11 Fields:
-
Comparative Protein Structure Modeling Using MODELLER. Curr Protoc Bioinformatics. 2014 Sep 08; 47:5.6.1-32.
Webb B, Sali A. PMID: 25199792.
View in:
PubMed Mentions:
491 Fields:
Translation:
Cells
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Molecular architecture of the 40S⋅eIF1⋅eIF3 translation initiation complex. Cell. 2014 08 28; 158(5):1123-1135.
Erzberger JP, Stengel F, Pellarin R, Zhang S, Schaefer T, Aylett CHS, Cimermancic P, Boehringer D, Sali A, Aebersold R, Ban N. PMID: 25171412; PMCID: PMC4151992.
View in:
PubMed Mentions:
119 Fields:
Translation:
HumansAnimalsCells
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Uncertainty in integrative structural modeling. Curr Opin Struct Biol. 2014 Oct; 28:96-104.
Schneidman-Duhovny D, Pellarin R, Sali A. PMID: 25173450; PMCID: PMC4252396.
View in:
PubMed Mentions:
48 Fields:
Translation:
Cells
-
Structural characterization by cross-linking reveals the detailed architecture of a coatomer-related heptameric module from the nuclear pore complex. Mol Cell Proteomics. 2014 Nov; 13(11):2927-43.
Shi Y, Fernandez-Martinez J, Tjioe E, Pellarin R, Kim SJ, Williams R, Schneidman-Duhovny D, Sali A, Rout MP, Chait BT. PMID: 25161197; PMCID: PMC4223482.
View in:
PubMed Mentions:
109 Fields:
Translation:
AnimalsCells
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Molecular architecture of photoreceptor phosphodiesterase elucidated by chemical cross-linking and integrative modeling. J Mol Biol. 2014 Nov 11; 426(22):3713-3728.
Zeng-Elmore X, Gao XZ, Pellarin R, Schneidman-Duhovny D, Zhang XJ, Kozacka KA, Tang Y, Sali A, Chalkley RJ, Cote RH, Chu F. PMID: 25149264; PMCID: PMC4253074.
View in:
PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Determining protein complex structures based on a Bayesian model of in vivo Förster resonance energy transfer (FRET) data. Mol Cell Proteomics. 2014 Nov; 13(11):2812-23.
Bonomi M, Pellarin R, Kim SJ, Russel D, Sundin BA, Riffle M, Jaschob D, Ramsden R, Davis TN, Muller EG, Sali A. PMID: 25139910; PMCID: PMC4223474.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
-
Integrative structure-function mapping of the nucleoporin Nup133 suggests a conserved mechanism for membrane anchoring of the nuclear pore complex. Mol Cell Proteomics. 2014 Nov; 13(11):2911-26.
Kim SJ, Fernandez-Martinez J, Sampathkumar P, Martel A, Matsui T, Tsuruta H, Weiss TM, Shi Y, Markina-Inarrairaegui A, Bonanno JB, Sauder JM, Burley SK, Chait BT, Almo SC, Rout MP, Sali A. PMID: 25139911; PMCID: PMC4223481.
View in:
PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
-
Cys-scanning disulfide crosslinking and bayesian modeling probe the transmembrane signaling mechanism of the histidine kinase, PhoQ. Structure. 2014 Sep 02; 22(9):1239-1251.
Molnar KS, Bonomi M, Pellarin R, Clinthorne GD, Gonzalez G, Goldberg SD, Goulian M, Sali A, DeGrado WF. PMID: 25087511; PMCID: PMC4322757.
View in:
PubMed Mentions:
66 Fields:
Translation:
Cells
-
Molecular architecture and function of the SEA complex, a modulator of the TORC1 pathway. Mol Cell Proteomics. 2014 Nov; 13(11):2855-70.
Algret R, Fernandez-Martinez J, Shi Y, Kim SJ, Pellarin R, Cimermancic P, Cochet E, Sali A, Chait BT, Rout MP, Dokudovskaya S. PMID: 25073740; PMCID: PMC4223477.
View in:
PubMed Mentions:
45 Fields:
Translation:
AnimalsCells
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Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters. Cell. 2014 Jul 17; 158(2):412-421.
Cimermancic P, Medema MH, Claesen J, Kurita K, Wieland Brown LC, Mavrommatis K, Pati A, Godfrey PA, Koehrsen M, Clardy J, Birren BW, Takano E, Sali A, Linington RG, Fischbach MA. PMID: 25036635; PMCID: PMC4123684.
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PubMed Mentions:
443 Fields:
Translation:
Cells
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Prediction of substrates for glutathione transferases by covalent docking. J Chem Inf Model. 2014 Jun 23; 54(6):1687-99.
Dong GQ, Calhoun S, Fan H, Kalyanaraman C, Branch MC, Mashiyama ST, London N, Jacobson MP, Babbitt PC, Shoichet BK, Armstrong RN, Sali A. PMID: 24802635; PMCID: PMC4068255.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Elucidating the mechanism of substrate recognition by the bacterial Hsp90 molecular chaperone. J Mol Biol. 2014 Jun 12; 426(12):2393-404.
Street TO, Zeng X, Pellarin R, Bonomi M, Sali A, Kelly MJ, Chu F, Agard DA. PMID: 24726919; PMCID: PMC5322795.
View in:
PubMed Mentions:
21 Fields:
Translation:
Cells
-
Protein structure modeling with MODELLER. Methods Mol Biol. 2014; 1137:1-15.
Webb B, Sali A. PMID: 24573470.
View in:
PubMed Mentions:
276 Fields:
Translation:
Cells
-
Modeling of proteins and their assemblies with the Integrative Modeling Platform. Methods Mol Biol. 2014; 1091:277-95.
Webb B, Lasker K, Velázquez-Muriel J, Schneidman-Duhovny D, Pellarin R, Bonomi M, Greenberg C, Raveh B, Tjioe E, Russel D, Sali A. PMID: 24203340.
View in:
PubMed Mentions:
20 Fields:
Translation:
Cells
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SAXS Merge: an automated statistical method to merge SAXS profiles using Gaussian processes. J Synchrotron Radiat. 2014 Jan; 21(Pt 1):203-8.
Spill YG, Kim SJ, Schneidman-Duhovny D, Russel D, Webb B, Sali A, Nilges M. PMID: 24365937; PMCID: PMC3874021.
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PubMed Mentions:
11 Fields:
-
ModBase, a database of annotated comparative protein structure models and associated resources. Nucleic Acids Res. 2014 Jan; 42(Database issue):D336-46.
Pieper U, Webb BM, Dong GQ, Schneidman-Duhovny D, Fan H, Kim SJ, Khuri N, Spill YG, Weinkam P, Hammel M, Tainer JA, Nilges M, Sali A. PMID: 24271400; PMCID: PMC3965011.
View in:
PubMed Mentions:
137 Fields:
Translation:
HumansCells
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High-resolution network biology: connecting sequence with function. Nat Rev Genet. 2013 Dec; 14(12):865-79.
Ryan CJ, Cimermancic P, Szpiech ZA, Sali A, Hernandez RD, Krogan NJ. PMID: 24197012; PMCID: PMC4023809.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansAnimalsCells
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Recovering a representative conformational ensemble from underdetermined macromolecular structural data. J Am Chem Soc. 2013 Nov 06; 135(44):16595-609.
Berlin K, Castañeda CA, Schneidman-Duhovny D, Sali A, Nava-Tudela A, Fushman D. PMID: 24093873; PMCID: PMC3902174.
View in:
PubMed Mentions:
55 Fields:
Translation:
HumansCells
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Target prediction for an open access set of compounds active against Mycobacterium tuberculosis. PLoS Comput Biol. 2013; 9(10):e1003253.
Martínez-Jiménez F, Papadatos G, Yang L, Wallace IM, Kumar V, Pieper U, Sali A, Brown JR, Overington JP, Marti-Renom MA. PMID: 24098102; PMCID: PMC3789770.
View in:
PubMed Mentions:
27 Fields:
Translation:
Cells
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Optimized atomic statistical potentials: assessment of protein interfaces and loops. Bioinformatics. 2013 Dec 15; 29(24):3158-66.
Dong GQ, Fan H, Schneidman-Duhovny D, Webb B, Sali A. PMID: 24078704; PMCID: PMC3842762.
View in:
PubMed Mentions:
62 Fields:
Translation:
Cells
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Mapping polymerization and allostery of hemoglobin S using point mutations. J Phys Chem B. 2013 Oct 24; 117(42):13058-68.
Weinkam P, Sali A. PMID: 23957820; PMCID: PMC3973026.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Structure-guided discovery of new deaminase enzymes. J Am Chem Soc. 2013 Sep 18; 135(37):13927-33.
Hitchcock DS, Fan H, Kim J, Vetting M, Hillerich B, Seidel RD, Almo SC, Shoichet BK, Sali A, Raushel FM. PMID: 23968233; PMCID: PMC3827683.
View in:
PubMed Mentions:
10 Fields:
Translation:
Cells
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Deamination of 6-aminodeoxyfutalosine in menaquinone biosynthesis by distantly related enzymes. Biochemistry. 2013 Sep 17; 52(37):6525-36.
Goble AM, Toro R, Li X, Ornelas A, Fan H, Eswaramoorthy S, Patskovsky Y, Hillerich B, Seidel R, Sali A, Shoichet BK, Almo SC, Swaminathan S, Tanner ME, Raushel FM. PMID: 23972005; PMCID: PMC3813303.
View in:
PubMed Mentions:
5 Fields:
Translation:
Cells
-
Celebrating 20 years of Structure. Structure. 2013 Sep 03; 21(9):1477-8.
Lima CD, Sali A, Kostic M. PMID: 24010704.
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PubMed Mentions: Fields:
-
Accurate SAXS profile computation and its assessment by contrast variation experiments. Biophys J. 2013 Aug 20; 105(4):962-74.
Schneidman-Duhovny D, Hammel M, Tainer JA, Sali A. PMID: 23972848; PMCID: PMC3752106.
View in:
PubMed Mentions:
288 Fields:
Translation:
Cells
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Consequences of domain insertion on sequence-structure divergence in a superfold. Proc Natl Acad Sci U S A. 2013 Sep 03; 110(36):E3381-7.
Pandya C, Brown S, Pieper U, Sali A, Dunaway-Mariano D, Babbitt PC, Xia Y, Allen KN. PMID: 23959887; PMCID: PMC3767544.
View in:
PubMed Mentions:
16 Fields:
Translation:
Cells
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Report of the wwPDB Small-Angle Scattering Task Force: data requirements for biomolecular modeling and the PDB. Structure. 2013 Jun 04; 21(6):875-81.
Trewhella J, Hendrickson WA, Kleywegt GJ, Sali A, Sato M, Schwede T, Svergun DI, Tainer JA, Westbrook J, Berman HM. PMID: 23747111.
View in:
PubMed Mentions:
42 Fields:
Translation:
Cells
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Structural basis for alternating access of a eukaryotic calcium/proton exchanger. Nature. 2013 Jul 04; 499(7456):107-10.
Waight AB, Pedersen BP, Schlessinger A, Bonomi M, Chau BH, Roe-Zurz Z, Risenmay AJ, Sali A, Stroud RM. PMID: 23685453; PMCID: PMC3702627.
View in:
PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
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Evolution of modular intraflagellar transport from a coatomer-like progenitor. Proc Natl Acad Sci U S A. 2013 Apr 23; 110(17):6943-8.
van Dam TJ, Townsend MJ, Turk M, Schlessinger A, Sali A, Field MC, Huynen MA. PMID: 23569277; PMCID: PMC3637775.
View in:
PubMed Mentions:
87 Fields:
Translation:
HumansAnimalsCells
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Crystal structure of a eukaryotic phosphate transporter. Nature. 2013 Apr 25; 496(7446):533-6.
Pedersen BP, Kumar H, Waight AB, Risenmay AJ, Roe-Zurz Z, Chau BH, Schlessinger A, Bonomi M, Harries W, Sali A, Johri AK, Stroud RM. PMID: 23542591; PMCID: PMC3678552.
View in:
PubMed Mentions:
97 Fields:
Translation:
HumansAnimalsCells
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Structure-based ligand discovery for the Large-neutral Amino Acid Transporter 1, LAT-1. Proc Natl Acad Sci U S A. 2013 Apr 02; 110(14):5480-5.
Geier EG, Schlessinger A, Fan H, Gable JE, Irwin JJ, Sali A, Giacomini KM. PMID: 23509259; PMCID: PMC3619328.
View in:
PubMed Mentions:
90 Fields:
Translation:
HumansCells
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Structure, dynamics, evolution, and function of a major scaffold component in the nuclear pore complex. Structure. 2013 Apr 02; 21(4):560-71.
Sampathkumar P, Kim SJ, Upla P, Rice WJ, Phillips J, Timney BL, Pieper U, Bonanno JB, Fernandez-Martinez J, Hakhverdyan Z, Ketaren NE, Matsui T, Weiss TM, Stokes DL, Sauder JM, Burley SK, Sali A, Rout MP, Almo SC. PMID: 23499021; PMCID: PMC3755625.
View in:
PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
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All-atom ensemble modeling to analyze small-angle x-ray scattering of glycosylated proteins. Structure. 2013 Mar 05; 21(3):321-31.
Guttman M, Weinkam P, Sali A, Lee KK. PMID: 23473666; PMCID: PMC3840220.
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PubMed Mentions:
41 Fields:
Translation:
HumansAnimalsCells
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Biochemistry. Integrative structural biology. Science. 2013 Feb 22; 339(6122):913-5.
Ward AB, Sali A, Wilson IA. PMID: 23430643; PMCID: PMC3633482.
View in:
PubMed Mentions:
119 Fields:
Translation:
Cells
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Coordinating the impact of structural genomics on the human α-helical transmembrane proteome. Nat Struct Mol Biol. 2013 Feb; 20(2):135-8.
Pieper U, Schlessinger A, Kloppmann E, Chang GA, Chou JJ, Dumont ME, Fox BG, Fromme P, Hendrickson WA, Malkowski MG, Rees DC, Stokes DL, Stowell MH, Wiener MC, Rost B, Stroud RM, Stevens RC, Sali A. PMID: 23381628; PMCID: PMC3645303.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansCells
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Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling. J Med Chem. 2013 Feb 14; 56(3):781-795.
Wittwer MB, Zur AA, Khuri N, Kido Y, Kosaka A, Zhang X, Morrissey KM, Sali A, Huang Y, Giacomini KM. PMID: 23241029; PMCID: PMC4068829.
View in:
PubMed Mentions:
59 Fields:
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Assignment of pterin deaminase activity to an enzyme of unknown function guided by homology modeling and docking. J Am Chem Soc. 2013 Jan 16; 135(2):795-803.
Fan H, Hitchcock DS, Seidel RD, Hillerich B, Lin H, Almo SC, Sali A, Shoichet BK, Raushel FM. PMID: 23256477; PMCID: PMC3557803.
View in:
PubMed Mentions:
18 Fields:
Translation:
Cells
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Molecular modeling and ligand docking for solute carrier (SLC) transporters. Curr Top Med Chem. 2013; 13(7):843-56.
Schlessinger A, Khuri N, Giacomini KM, Sali A. PMID: 23578028; PMCID: PMC4056341.
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PubMed Mentions:
36 Fields:
Translation:
Humans
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Impact of mutations on the allosteric conformational equilibrium. J Mol Biol. 2013 Feb 08; 425(3):647-61.
Weinkam P, Chen YC, Pons J, Sali A. PMID: 23228330; PMCID: PMC3557769.
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PubMed Mentions:
26 Fields:
Translation:
Cells
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Limits of ligand selectivity from docking to models: in silico screening for A(1) adenosine receptor antagonists. PLoS One. 2012; 7(11):e49910.
Kolb P, Phan K, Gao ZG, Marko AC, Sali A, Jacobson KA. PMID: 23185482; PMCID: PMC3503826.
View in:
PubMed Mentions:
19 Fields:
Translation:
Cells
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Assembly of macromolecular complexes by satisfaction of spatial restraints from electron microscopy images. Proc Natl Acad Sci U S A. 2012 Nov 13; 109(46):18821-6.
Velázquez-Muriel J, Lasker K, Russel D, Phillips J, Webb BM, Schneidman-Duhovny D, Sali A. PMID: 23112201; PMCID: PMC3503186.
View in:
PubMed Mentions:
26 Fields:
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A method for integrative structure determination of protein-protein complexes. Bioinformatics. 2012 Dec 15; 28(24):3282-9.
Schneidman-Duhovny D, Rossi A, Avila-Sakar A, Kim SJ, Velázquez-Muriel J, Strop P, Liang H, Krukenberg KA, Liao M, Kim HM, Sobhanifar S, Dötsch V, Rajpal A, Pons J, Agard DA, Cheng Y, Sali A. PMID: 23093611; PMCID: PMC3519461.
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PubMed Mentions:
38 Fields:
Translation:
Cells
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Self-assembly of filamentous amelogenin requires calcium and phosphate: from dimers via nanoribbons to fibrils. Biomacromolecules. 2012 Nov 12; 13(11):3494-502.
Martinez-Avila O, Wu S, Kim SJ, Cheng Y, Khan F, Samudrala R, Sali A, Horst JA, Habelitz S. PMID: 22974364; PMCID: PMC3496023.
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PubMed Mentions:
26 Fields:
Translation:
Cells
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In support of the BMRB. Nat Struct Mol Biol. 2012 Sep; 19(9):854-60.
Markley JL, Akutsu H, Asakura T, Baldus M, Boelens R, Bonvin A, Kaptein R, Bax A, Bezsonova I, Gryk MR, Hoch JC, Korzhnev DM, Maciejewski MW, Case D, Chazin WJ, Cross TA, Dames S, Kessler H, Lange O, Madl T, Reif B, Sattler M, Eliezer D, Fersht A, Forman-Kay J, Kay LE, Fraser J, Gross J, Kortemme T, Sali A, Fujiwara T, Gardner K, Luo X, Rizo-Rey J, Rosen M, Gil RR, Ho C, Rule G, Gronenborn AM, Ishima R, Klein-Seetharaman J, Tang P, van der Wel P, Xu Y, Grzesiek S, Hiller S, Seelig J, Laue ED, Mott H, Nietlispach D, Barsukov I, Lian LY, Middleton D, Blumenschein T, Moore G, Campbell I, Schnell J, Vakonakis IJ, Watts A, Conte MR, Mason J, Pfuhl M, Sanderson MR, Craven J, Williamson M, Dominguez C, Roberts G, Günther U, Overduin M, Werner J, Williamson P, Blindauer C, Crump M, Driscoll P, Frenkiel T, Golovanov A, Matthews S, Parkinson J, Uhrin D, Williams M, Neuhaus D, Oschkinat H, Ramos A, Shaw DE, Steinbeck C, Vendruscolo M, Vuister GW, Walters KJ, Weinstein H, Wüthrich K, Yokoyama S. PMID: 22955930.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Strategic protein target analysis for developing drugs to stop dental caries. Adv Dent Res. 2012 Sep; 24(2):86-93.
Horst JA, Pieper U, Sali A, Zhan L, Chopra G, Samudrala R, Featherstone JD. PMID: 22899687; PMCID: PMC3420364.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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High selectivity of the γ-aminobutyric acid transporter 2 (GAT-2, SLC6A13) revealed by structure-based approach. J Biol Chem. 2012 Nov 02; 287(45):37745-56.
Schlessinger A, Wittwer MB, Dahlin A, Khuri N, Bonomi M, Fan H, Giacomini KM, Sali A. PMID: 22932902; PMCID: PMC3488050.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Integrative structural modeling with small angle X-ray scattering profiles. BMC Struct Biol. 2012 Jul 16; 12:17.
Schneidman-Duhovny D, Kim SJ, Sali A. PMID: 22800408; PMCID: PMC3427135.
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PubMed Mentions:
49 Fields:
Translation:
Cells
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Atomic structure of the nuclear pore complex targeting domain of a Nup116 homologue from the yeast, Candida glabrata. Proteins. 2012 Aug; 80(8):2110-6.
Sampathkumar P, Kim SJ, Manglicmot D, Bain KT, Gilmore J, Gheyi T, Phillips J, Pieper U, Fernandez-Martinez J, Franke JD, Matsui T, Tsuruta H, Atwell S, Thompson DA, Emtage JS, Wasserman SR, Rout MP, Sali A, Sauder JM, Almo SC, Burley SK. PMID: 22544723; PMCID: PMC3686472.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse. Mol Cell Proteomics. 2012 Aug; 11(8):215-29.
Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL. PMID: 22645316; PMCID: PMC3412957.
View in:
PubMed Mentions:
212 Fields:
Translation:
AnimalsCells
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SALIGN: a web server for alignment of multiple protein sequences and structures. Bioinformatics. 2012 Aug 01; 28(15):2072-3.
Braberg H, Webb BM, Tjioe E, Pieper U, Sali A, Madhusudhan MS. PMID: 22618536; PMCID: PMC3400954.
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PubMed Mentions:
40 Fields:
Translation:
Cells
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Facile backbone structure determination of human membrane proteins by NMR spectroscopy. Nat Methods. 2012 May 20; 9(8):834-9.
Klammt C, Maslennikov I, Bayrhuber M, Eichmann C, Vajpai N, Chiu EJ, Blain KY, Esquivies L, Kwon JH, Balana B, Pieper U, Sali A, Slesinger PA, Kwiatkowski W, Riek R, Choe S. PMID: 22609626; PMCID: PMC3723349.
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PubMed Mentions:
40 Fields:
Translation:
HumansCells
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Structure-based model of allostery predicts coupling between distant sites. Proc Natl Acad Sci U S A. 2012 Mar 27; 109(13):4875-80.
Weinkam P, Pons J, Sali A. PMID: 22403063; PMCID: PMC3324024.
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PubMed Mentions:
81 Fields:
Translation:
Cells
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Biochemical characterization and structural modeling of human cathepsin E variant 2 in comparison to the wild-type protein. Biol Chem. 2012 Mar; 393(3):177-86.
Puizdar V, Zajc T, Zerovnik E, Renko M, Pieper U, Eswar N, Sali A, Dolenc I, Turk V. PMID: 22718633; PMCID: PMC4111641.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Structure-function mapping of a heptameric module in the nuclear pore complex. J Cell Biol. 2012 Feb 20; 196(4):419-34.
Fernandez-Martinez J, Phillips J, Sekedat MD, Diaz-Avalos R, Velazquez-Muriel J, Franke JD, Williams R, Stokes DL, Chait BT, Sali A, Rout MP. PMID: 22331846; PMCID: PMC3283990.
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PubMed Mentions:
72 Fields:
Translation:
AnimalsCells
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Outcome of the first electron microscopy validation task force meeting. Structure. 2012 Feb 08; 20(2):205-14.
Henderson R, Sali A, Baker ML, Carragher B, Devkota B, Downing KH, Egelman EH, Feng Z, Frank J, Grigorieff N, Jiang W, Ludtke SJ, Medalia O, Penczek PA, Rosenthal PB, Rossmann MG, Schmid MF, Schröder GF, Steven AC, Stokes DL, Westbrook JD, Wriggers W, Yang H, Young J, Berman HM, Chiu W, Kleywegt GJ, Lawson CL. PMID: 22325770; PMCID: PMC3328769.
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PubMed Mentions:
292 Fields:
Translation:
HumansAnimalsCells
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Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach. Proc Natl Acad Sci U S A. 2012 Jan 31; 109(5):1380-7.
Lasker K, Förster F, Bohn S, Walzthoeni T, Villa E, Unverdorben P, Beck F, Aebersold R, Sali A, Baumeister W. PMID: 22307589; PMCID: PMC3277140.
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PubMed Mentions:
246 Fields:
Translation:
AnimalsCells
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Putting the pieces together: integrative modeling platform software for structure determination of macromolecular assemblies. PLoS Biol. 2012 Jan; 10(1):e1001244.
Russel D, Lasker K, Webb B, Velázquez-Muriel J, Tjioe E, Schneidman-Duhovny D, Peterson B, Sali A. PMID: 22272186; PMCID: PMC3260315.
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PubMed Mentions:
274 Fields:
Translation:
Humans
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Macromolecular assembly structures by comparative modeling and electron microscopy. Methods Mol Biol. 2012; 857:331-50.
Lasker K, Velázquez-Muriel JA, Webb BM, Yang Z, Ferrin TE, Sali A. PMID: 22323229.
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PubMed Mentions:
3 Fields:
Translation:
Cells
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Virtual ligand screening against comparative protein structure models. Methods Mol Biol. 2012; 819:105-26.
Fan H, Irwin JJ, Sali A. PMID: 22183533; PMCID: PMC3386294.
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PubMed Mentions:
6 Fields:
Translation:
Cells
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Global landscape of HIV-human protein complexes. Nature. 2011 Dec 21; 481(7381):365-70.
Jäger S, Cimermancic P, Gulbahce N, Johnson JR, McGovern KE, Clarke SC, Shales M, Mercenne G, Pache L, Li K, Hernandez H, Jang GM, Roth SL, Akiva E, Marlett J, Stephens M, D'Orso I, Fernandes J, Fahey M, Mahon C, O'Donoghue AJ, Todorovic A, Morris JH, Maltby DA, Alber T, Cagney G, Bushman FD, Young JA, Chanda SK, Sundquist WI, Kortemme T, Hernandez RD, Craik CS, Burlingame A, Sali A, Frankel AD, Krogan NJ. PMID: 22190034; PMCID: PMC3310911.
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PubMed Mentions:
427 Fields:
Translation:
HumansCells
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Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection. Nature. 2011 Dec 21; 481(7381):371-5.
Jäger S, Kim DY, Hultquist JF, Shindo K, LaRue RS, Kwon E, Li M, Anderson BD, Yen L, Stanley D, Mahon C, Kane J, Franks-Skiba K, Cimermancic P, Burlingame A, Sali A, Craik CS, Harris RS, Gross JD, Krogan NJ. PMID: 22190037; PMCID: PMC3310910.
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PubMed Mentions:
228 Fields:
Translation:
HumansAnimalsCells
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The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes together. Proc Natl Acad Sci U S A. 2012 Jan 03; 109(1):149-54.
Pathare GR, Nagy I, Bohn S, Unverdorben P, Hubert A, Körner R, Nickell S, Lasker K, Sali A, Tamura T, Nishioka T, Förster F, Baumeister W, Bracher A. PMID: 22187461; PMCID: PMC3252951.
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PubMed Mentions:
88 Fields:
Translation:
AnimalsCells
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Statistical potential for modeling and ranking of protein-ligand interactions. J Chem Inf Model. 2011 Dec 27; 51(12):3078-92.
Fan H, Schneidman-Duhovny D, Irwin JJ, Dong G, Shoichet BK, Sali A. PMID: 22014038; PMCID: PMC3246566.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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The Enzyme Function Initiative. Biochemistry. 2011 Nov 22; 50(46):9950-62.
Gerlt JA, Allen KN, Almo SC, Armstrong RN, Babbitt PC, Cronan JE, Dunaway-Mariano D, Imker HJ, Jacobson MP, Minor W, Poulter CD, Raushel FM, Sali A, Shoichet BK, Sweedler JV. PMID: 21999478; PMCID: PMC3238057.
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PubMed Mentions:
95 Fields:
Translation:
HumansAnimalsCells
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Structure meets the membrane. Structure. 2011 Oct 12; 19(10):1347.
Lima C, Sali A, Kostic M. PMID: 22000504.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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UCSF Chimera, MODELLER, and IMP: an integrated modeling system. J Struct Biol. 2012 Sep; 179(3):269-78.
Yang Z, Lasker K, Schneidman-Duhovny D, Webb B, Huang CC, Pettersen EF, Goddard TD, Meng EC, Sali A, Ferrin TE. PMID: 21963794; PMCID: PMC3410985.
View in:
PubMed Mentions:
281 Fields:
Translation:
AnimalsCells
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Ligand discovery from a dopamine D3 receptor homology model and crystal structure. Nat Chem Biol. 2011 Sep 18; 7(11):769-78.
Carlsson J, Coleman RG, Setola V, Irwin JJ, Fan H, Schlessinger A, Sali A, Roth BL, Shoichet BK. PMID: 21926995; PMCID: PMC3197762.
View in:
PubMed Mentions:
129 Fields:
Translation:
Cells
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Structure-based discovery of prescription drugs that interact with the norepinephrine transporter, NET. Proc Natl Acad Sci U S A. 2011 Sep 20; 108(38):15810-5.
Schlessinger A, Geier E, Fan H, Irwin JJ, Shoichet BK, Giacomini KM, Sali A. PMID: 21885739; PMCID: PMC3179104.
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PubMed Mentions:
67 Fields:
Translation:
HumansCells
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Discovery of a cytokinin deaminase. ACS Chem Biol. 2011 Oct 21; 6(10):1036-40.
Goble AM, Fan H, Sali A, Raushel FM. PMID: 21823622; PMCID: PMC3199332.
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PubMed Mentions:
11 Fields:
Translation:
Cells
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MultiFit: a web server for fitting multiple protein structures into their electron microscopy density map. Nucleic Acids Res. 2011 Jul; 39(Web Server issue):W167-70.
Tjioe E, Lasker K, Webb B, Wolfson HJ, Sali A. PMID: 21715383; PMCID: PMC3125811.
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PubMed Mentions:
16 Fields:
-
Evolution: On a bender--BARs, ESCRTs, COPs, and finally getting your coat. J Cell Biol. 2011 Jun 13; 193(6):963-72.
Field MC, Sali A, Rout MP. PMID: 21670211; PMCID: PMC3115789.
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PubMed Mentions:
57 Fields:
Translation:
AnimalsCells
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A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in Saccharomyces cerevisiae. Mol Cell Proteomics. 2011 Jun; 10(6):M110.006478.
Dokudovskaya S, Waharte F, Schlessinger A, Pieper U, Devos DP, Cristea IM, Williams R, Salamero J, Chait BT, Sali A, Field MC, Rout MP, Dargemont C. PMID: 21454883; PMCID: PMC3108837.
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PubMed Mentions:
83 Fields:
Translation:
AnimalsCells
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Structure of the C-terminal domain of Saccharomyces cerevisiae Nup133, a component of the nuclear pore complex. Proteins. 2011 May; 79(5):1672-7.
Sampathkumar P, Gheyi T, Miller SA, Bain KT, Dickey M, Bonanno JB, Kim SJ, Phillips J, Pieper U, Fernandez-Martinez J, Franke JD, Martel A, Tsuruta H, Atwell S, Thompson DA, Emtage JS, Wasserman SR, Rout MP, Sali A, Sauder JM, Burley SK. PMID: 21365675; PMCID: PMC3350809.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Catalytic mechanism and three-dimensional structure of adenine deaminase. Biochemistry. 2011 Mar 22; 50(11):1917-27.
Kamat SS, Bagaria A, Kumaran D, Holmes-Hampton GP, Fan H, Sali A, Sauder JM, Burley SK, Lindahl PA, Swaminathan S, Raushel FM. PMID: 21247091; PMCID: PMC3059353.
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PubMed Mentions:
27 Fields:
Translation:
Cells
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Enzymatic deamination of the epigenetic base N-6-methyladenine. J Am Chem Soc. 2011 Feb 23; 133(7):2080-3.
Kamat SS, Fan H, Sauder JM, Burley SK, Shoichet BK, Sali A, Raushel FM. PMID: 21275375; PMCID: PMC3043370.
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PubMed Mentions:
20 Fields:
Translation:
Cells
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Modeling of proteins and their assemblies with the integrative modeling platform. Methods Mol Biol. 2011; 781:377-97.
Webb B, Lasker K, Schneidman-Duhovny D, Tjioe E, Phillips J, Kim SJ, Velázquez-Muriel J, Russel D, Sali A. PMID: 21877292.
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PubMed Mentions:
15 Fields:
Translation:
Cells
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ModBase, a database of annotated comparative protein structure models, and associated resources. Nucleic Acids Res. 2011 Jan; 39(Database issue):D465-74.
Pieper U, Webb BM, Barkan DT, Schneidman-Duhovny D, Schlessinger A, Braberg H, Yang Z, Meng EC, Pettersen EF, Huang CC, Datta RS, Sampathkumar P, Madhusudhan MS, Sjölander K, Ferrin TE, Burley SK, Sali A. PMID: 21097780; PMCID: PMC3013688.
View in:
PubMed Mentions:
143 Fields:
Translation:
Cells
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Determining macromolecular assembly structures by molecular docking and fitting into an electron density map. Proteins. 2010 Nov 15; 78(15):3205-11.
Lasker K, Sali A, Wolfson HJ. PMID: 20827723; PMCID: PMC2952722.
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PubMed Mentions:
36 Fields:
Translation:
Cells
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Functional hot spots in human ATP-binding cassette transporter nucleotide binding domains. Protein Sci. 2010 Nov; 19(11):2110-21.
Kelly L, Fukushima H, Karchin R, Gow JM, Chinn LW, Pieper U, Segal MR, Kroetz DL, Sali A. PMID: 20799350; PMCID: PMC3005782.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Structure of a putative BenF-like porin from Pseudomonas fluorescens Pf-5 at 2.6 A resolution. Proteins. 2010 Nov 01; 78(14):3056-62.
Sampathkumar P, Lu F, Zhao X, Li Z, Gilmore J, Bain K, Rutter ME, Gheyi T, Schwinn KD, Bonanno JB, Pieper U, Fajardo JE, Fiser A, Almo SC, Swaminathan S, Chance MR, Baker D, Atwell S, Thompson DA, Emtage JS, Wasserman SR, Sali A, Sauder JM, Burley SK. PMID: 20737437; PMCID: PMC2989796.
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PubMed Mentions:
7 Fields:
Translation:
Cells
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Role of organic cation transporter 3 (SLC22A3) and its missense variants in the pharmacologic action of metformin. Pharmacogenet Genomics. 2010 Nov; 20(11):687-99.
Chen L, Pawlikowski B, Schlessinger A, More SS, Stryke D, Johns SJ, Portman MA, Chen E, Ferrin TE, Sali A, Giacomini KM. PMID: 20859243; PMCID: PMC2976715.
View in:
PubMed Mentions:
104 Fields:
Translation:
Cells
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Macromolecular docking restrained by a small angle X-ray scattering profile. J Struct Biol. 2011 Mar; 173(3):461-71.
Schneidman-Duhovny D, Hammel M, Sali A. PMID: 20920583; PMCID: PMC3040266.
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PubMed Mentions:
37 Fields:
Translation:
Cells
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Structures of the autoproteolytic domain from the Saccharomyces cerevisiae nuclear pore complex component, Nup145. Proteins. 2010 Jun; 78(8):1992-8.
Sampathkumar P, Ozyurt SA, Do J, Bain KT, Dickey M, Rodgers LA, Gheyi T, Sali A, Kim SJ, Phillips J, Pieper U, Fernandez-Martinez J, Franke JD, Martel A, Tsuruta H, Atwell S, Thompson DA, Emtage JS, Wasserman SR, Rout MP, Sauder JM, Burley SK. PMID: 20310066; PMCID: PMC3136511.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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FoXS: a web server for rapid computation and fitting of SAXS profiles. Nucleic Acids Res. 2010 Jul; 38(Web Server issue):W540-4.
Schneidman-Duhovny D, Hammel M, Sali A. PMID: 20507903; PMCID: PMC2896111.
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PubMed Mentions:
292 Fields:
Translation:
Cells
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Integrative structure modeling of macromolecular assemblies from proteomics data. Mol Cell Proteomics. 2010 Aug; 9(8):1689-702.
Lasker K, Phillips JL, Russel D, Velázquez-Muriel J, Schneidman-Duhovny D, Tjioe E, Webb B, Schlessinger A, Sali A. PMID: 20507923; PMCID: PMC2938050.
View in:
PubMed Mentions:
36 Fields:
Translation:
Humans
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Prediction of protease substrates using sequence and structure features. Bioinformatics. 2010 Jul 15; 26(14):1714-22.
Barkan DT, Hostetter DR, Mahrus S, Pieper U, Wells JA, Craik CS, Sali A. PMID: 20505003; PMCID: PMC2894511.
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PubMed Mentions:
31 Fields:
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Toward an integrated structural model of the 26S proteasome. Mol Cell Proteomics. 2010 Aug; 9(8):1666-77.
Förster F, Lasker K, Nickell S, Sali A, Baumeister W. PMID: 20467039; PMCID: PMC2938054.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Function of human Rh based on structure of RhCG at 2.1 A. Proc Natl Acad Sci U S A. 2010 May 25; 107(21):9638-43.
Gruswitz F, Chaudhary S, Ho JD, Schlessinger A, Pezeshki B, Ho CM, Sali A, Westhoff CM, Stroud RM. PMID: 20457942; PMCID: PMC2906887.
View in:
PubMed Mentions:
89 Fields:
Translation:
HumansCells
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Comparison of human solute carriers. Protein Sci. 2010 Mar; 19(3):412-28.
Schlessinger A, Matsson P, Shima JE, Pieper U, Yee SW, Kelly L, Apeltsin L, Stroud RM, Ferrin TE, Giacomini KM, Sali A. PMID: 20052679; PMCID: PMC2866268.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansCells
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The overlap of small molecule and protein binding sites within families of protein structures. PLoS Comput Biol. 2010 Feb 05; 6(2):e1000668.
Davis FP, Sali A. PMID: 20140189; PMCID: PMC2816688.
View in:
PubMed Mentions:
24 Fields:
Translation:
Cells
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Comprehensive molecular structure of the eukaryotic ribosome. Structure. 2009 Dec 09; 17(12):1591-1604.
Taylor DJ, Devkota B, Huang AD, Topf M, Narayanan E, Sali A, Harvey SC, Frank J. PMID: 20004163; PMCID: PMC2814252.
View in:
PubMed Mentions:
84 Fields:
Translation:
Cells
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Molecular docking screens using comparative models of proteins. J Chem Inf Model. 2009 Nov; 49(11):2512-27.
Fan H, Irwin JJ, Webb BM, Klebe G, Shoichet BK, Sali A. PMID: 19845314; PMCID: PMC2790034.
View in:
PubMed Mentions:
67 Fields:
Translation:
Cells
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Institutional Profile: The University of California Pharmacogenomics Center: at the interface of genomics, biological mechanisms and drug therapy. Pharmacogenomics. 2009 Oct; 10(10):1569-76.
Kroetz DL, Ahituv N, Burchard EG, Guo S, Sali A, Giacomini KM. PMID: 19842929; PMCID: PMC2923222.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
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A survey of integral alpha-helical membrane proteins. J Struct Funct Genomics. 2009 Dec; 10(4):269-80.
Kelly L, Pieper U, Eswar N, Hays FA, Li M, Roe-Zurz Z, Kroetz DL, Giacomini KM, Stroud RM, Sali A. PMID: 19760129; PMCID: PMC2780624.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Global motions of the nuclear pore complex: insights from elastic network models. PLoS Comput Biol. 2009 Sep; 5(9):e1000496.
Lezon TR, Sali A, Bahar I. PMID: 19730674; PMCID: PMC2725293.
View in:
PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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An atomic model AAA-ATPase/20S core particle sub-complex of the 26S proteasome. Biochem Biophys Res Commun. 2009 Oct 16; 388(2):228-33.
Förster F, Lasker K, Beck F, Nickell S, Sali A, Baumeister W. PMID: 19653995; PMCID: PMC2771176.
View in:
PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
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Alignment of multiple protein structures based on sequence and structure features. Protein Eng Des Sel. 2009 Sep; 22(9):569-74.
Madhusudhan MS, Webb BM, Marti-Renom MA, Eswar N, Sali A. PMID: 19587024; PMCID: PMC2909824.
View in:
PubMed Mentions:
34 Fields:
Translation:
Cells
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Insights into the molecular architecture of the 26S proteasome. Proc Natl Acad Sci U S A. 2009 Jul 21; 106(29):11943-7.
Nickell S, Beck F, Scheres SH, Korinek A, Förster F, Lasker K, Mihalache O, Sun N, Nagy I, Sali A, Plitzko JM, Carazo JM, Mann M, Baumeister W. PMID: 19581588; PMCID: PMC2715492.
View in:
PubMed Mentions:
60 Fields:
Translation:
Animals
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Evidence for a shared nuclear pore complex architecture that is conserved from the last common eukaryotic ancestor. Mol Cell Proteomics. 2009 Sep; 8(9):2119-30.
DeGrasse JA, DuBois KN, Devos D, Siegel TN, Sali A, Field MC, Rout MP, Chait BT. PMID: 19525551; PMCID: PMC2742445.
View in:
PubMed Mentions:
135 Fields:
Translation:
HumansAnimalsCells
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Evolutionary constraints on structural similarity in orthologs and paralogs. Protein Sci. 2009 Jun; 18(6):1306-15.
Peterson ME, Chen F, Saven JG, Roos DS, Babbitt PC, Sali A. PMID: 19472362; PMCID: PMC2774440.
View in:
PubMed Mentions:
32 Fields:
Translation:
Cells
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Regulatory elements within the prodomain of Falcipain-2, a cysteine protease of the malaria parasite Plasmodium falciparum. PLoS One. 2009 May 27; 4(5):e5694.
Pandey KC, Barkan DT, Sali A, Rosenthal PJ. PMID: 19479029; PMCID: PMC2682653.
View in:
PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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A kernel for open source drug discovery in tropical diseases. PLoS Negl Trop Dis. 2009; 3(4):e418.
Ortí L, Carbajo RJ, Pieper U, Eswar N, Maurer SM, Rai AK, Taylor G, Todd MH, Pineda-Lucena A, Sali A, Marti-Renom MA. PMID: 19381286; PMCID: PMC2667270.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
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ModLink+: improving fold recognition by using protein-protein interactions. Bioinformatics. 2009 Jun 15; 25(12):1506-12.
Fornes O, Aragues R, Espadaler J, Marti-Renom MA, Sali A, Oliva B. PMID: 19357100; PMCID: PMC2687990.
View in:
PubMed Mentions:
5 Fields:
Translation:
Cells
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A kernel for the Tropical Disease Initiative. Nat Biotechnol. 2009 Apr; 27(4):320-1.
Ortí L, Carbajo RJ, Pieper U, Eswar N, Maurer SM, Rai AK, Taylor G, Todd MH, Pineda-Lucena A, Sali A, Marti-Renom MA. PMID: 19352362; PMCID: PMC3088649.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
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Inferential optimization for simultaneous fitting of multiple components into a CryoEM map of their assembly. J Mol Biol. 2009 Apr 24; 388(1):180-94.
Lasker K, Topf M, Sali A, Wolfson HJ. PMID: 19233204; PMCID: PMC2680734.
View in:
PubMed Mentions:
63 Fields:
Translation:
Cells
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Target selection and annotation for the structural genomics of the amidohydrolase and enolase superfamilies. J Struct Funct Genomics. 2009 Apr; 10(2):107-25.
Pieper U, Chiang R, Seffernick JJ, Brown SD, Glasner ME, Kelly L, Eswar N, Sauder JM, Bonanno JB, Swaminathan S, Burley SK, Zheng X, Chance MR, Almo SC, Gerlt JA, Raushel FM, Jacobson MP, Babbitt PC, Sali A. PMID: 19219566; PMCID: PMC2693957.
View in:
PubMed Mentions:
19 Fields:
Translation:
Cells
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The structural dynamics of macromolecular processes. Curr Opin Cell Biol. 2009 Feb; 21(1):97-108.
Russel D, Lasker K, Phillips J, Schneidman-Duhovny D, Velázquez-Muriel JA, Sali A. PMID: 19223165; PMCID: PMC2774249.
View in:
PubMed Mentions:
24 Fields:
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Outcome of a workshop on applications of protein models in biomedical research. Structure. 2009 Feb 13; 17(2):151-9.
Schwede T, Sali A, Honig B, Levitt M, Berman HM, Jones D, Brenner SE, Burley SK, Das R, Dokholyan NV, Dunbrack RL, Fidelis K, Fiser A, Godzik A, Huang YJ, Humblet C, Jacobson MP, Joachimiak A, Krystek SR, Kortemme T, Kryshtafovych A, Montelione GT, Moult J, Murray D, Sanchez R, Sosnick TR, Standley DM, Stouch T, Vajda S, Vasquez M, Westbrook JD, Wilson IA. PMID: 19217386; PMCID: PMC2739730.
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PubMed Mentions:
87 Fields:
Translation:
HumansAnimalsCells
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2007 annual progress report synopsis of the Center for Structures of Membrane Proteins. J Struct Funct Genomics. 2009 Apr; 10(2):193-208.
Stroud RM, Choe S, Holton J, Kaback HR, Kwiatkowski W, Minor DL, Riek R, Sali A, Stahlberg H, Harries W. PMID: 19148774; PMCID: PMC2705707.
View in:
PubMed Mentions:
13 Fields:
Translation:
Cells
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Selecting optimum eukaryotic integral membrane proteins for structure determination by rapid expression and solubilization screening. J Mol Biol. 2009 Jan 23; 385(3):820-30.
Li M, Hays FA, Roe-Zurz Z, Vuong L, Kelly L, Ho CM, Robbins RM, Pieper U, O'Connell JD, Miercke LJ, Giacomini KM, Sali A, Stroud RM. PMID: 19061901; PMCID: PMC2659619.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCells
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Ratiocinative screen of eukaryotic integral membrane protein expression and solubilization for structure determination. J Struct Funct Genomics. 2009 Mar; 10(1):9-16.
Hays FA, Roe-Zurz Z, Li M, Kelly L, Gruswitz F, Sali A, Stroud RM. PMID: 19031011; PMCID: PMC2756966.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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MODBASE, a database of annotated comparative protein structure models and associated resources. Nucleic Acids Res. 2009 Jan; 37(Database issue):D347-54.
Pieper U, Eswar N, Webb BM, Eramian D, Kelly L, Barkan DT, Carter H, Mankoo P, Karchin R, Marti-Renom MA, Davis FP, Sali A. PMID: 18948282; PMCID: PMC2686492.
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PubMed Mentions:
75 Fields:
Translation:
HumansCells
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Genomic-scale prioritization of drug targets: the TDR Targets database. Nat Rev Drug Discov. 2008 11; 7(11):900-7.
Agüero F, Al-Lazikani B, Aslett M, Berriman M, Buckner FS, Campbell RK, Carmona S, Carruthers IM, Chan AW, Chen F, Crowther GJ, Doyle MA, Hertz-Fowler C, Hopkins AL, McAllister G, Nwaka S, Overington JP, Pain A, Paolini GV, Pieper U, Ralph SA, Riechers A, Roos DS, Sali A, Shanmugam D, Suzuki T, Van Voorhis WC, Verlinde CL. PMID: 18927591; PMCID: PMC3184002.
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PubMed Mentions:
130 Fields:
Translation:
HumansAnimals
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How well can the accuracy of comparative protein structure models be predicted? Protein Sci. 2008 Nov; 17(11):1881-93.
Eramian D, Eswar N, Shen MY, Sali A. PMID: 18832340; PMCID: PMC2578807.
View in:
PubMed Mentions:
69 Fields:
Translation:
Cells
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Global sequencing of proteolytic cleavage sites in apoptosis by specific labeling of protein N termini. Cell. 2008 Sep 05; 134(5):866-76.
Mahrus S, Trinidad JC, Barkan DT, Sali A, Burlingame AL, Wells JA. PMID: 18722006; PMCID: PMC2566540.
View in:
PubMed Mentions:
203 Fields:
Translation:
HumansCells
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Evolutionarily conserved substrate substructures for automated annotation of enzyme superfamilies. PLoS Comput Biol. 2008 Aug 01; 4(8):e1000142.
Chiang RA, Sali A, Babbitt PC. PMID: 18670595; PMCID: PMC2453236.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Integration of small-angle X-ray scattering data into structural modeling of proteins and their assemblies. J Mol Biol. 2008 Oct 17; 382(4):1089-106.
Förster F, Webb B, Krukenberg KA, Tsuruta H, Agard DA, Sali A. PMID: 18694757; PMCID: PMC2745287.
View in:
PubMed Mentions:
67 Fields:
Translation:
Cells
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Subnanometer-resolution electron cryomicroscopy-based domain models for the cytoplasmic region of skeletal muscle RyR channel. Proc Natl Acad Sci U S A. 2008 Jul 15; 105(28):9610-5.
Serysheva II, Ludtke SJ, Baker ML, Cong Y, Topf M, Eramian D, Sali A, Hamilton SL, Chiu W. PMID: 18621707; PMCID: PMC2474495.
View in:
PubMed Mentions:
60 Fields:
Translation:
Cells
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Mechanism of lid closure in the eukaryotic chaperonin TRiC/CCT. Nat Struct Mol Biol. 2008 Jul; 15(7):746-53.
Booth CR, Meyer AS, Cong Y, Topf M, Sali A, Ludtke SJ, Chiu W, Frydman J. PMID: 18536725; PMCID: PMC2546500.
View in:
PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
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Prediction of enzyme function by combining sequence similarity and protein interactions. BMC Bioinformatics. 2008 May 27; 9:249.
Espadaler J, Eswar N, Querol E, Avilés FX, Sali A, Marti-Renom MA, Oliva B. PMID: 18505562; PMCID: PMC2430716.
View in:
PubMed Mentions:
12 Fields:
Translation:
Cells
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Multiple conformations of E. coli Hsp90 in solution: insights into the conformational dynamics of Hsp90. Structure. 2008 May; 16(5):755-65.
Krukenberg KA, Förster F, Rice LM, Sali A, Agard DA. PMID: 18462680; PMCID: PMC2600884.
View in:
PubMed Mentions:
94 Fields:
Translation:
Cells
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Classifying Variants of Undetermined Significance in BRCA2 with protein likelihood ratios. Cancer Inform. 2008; 6:203-16.
Karchin R, Agarwal M, Sali A, Couch F, Beattie MS. PMID: 19043619; PMCID: PMC2587343.
View in:
PubMed Mentions:
26
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Structure of the mammalian 80S ribosome at 8.7 A resolution. Structure. 2008 Apr; 16(4):535-48.
Chandramouli P, Topf M, Ménétret JF, Eswar N, Cannone JJ, Gutell RR, Sali A, Akey CW. PMID: 18400176; PMCID: PMC2775484.
View in:
PubMed Mentions:
77 Fields:
Translation:
AnimalsCells
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Tel2 mediates activation and localization of ATM/Tel1 kinase to a double-strand break. Genes Dev. 2008 Apr 01; 22(7):854-9.
Anderson CM, Korkin D, Smith DL, Makovets S, Seidel JJ, Sali A, Blackburn EH. PMID: 18334620; PMCID: PMC2279195.
View in:
PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
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Protein structure fitting and refinement guided by cryo-EM density. Structure. 2008 Feb; 16(2):295-307.
Topf M, Lasker K, Webb B, Wolfson H, Chiu W, Sali A. PMID: 18275820; PMCID: PMC2409374.
View in:
PubMed Mentions:
195 Fields:
Translation:
Cells
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Protein production and purification. Nat Methods. 2008 Feb; 5(2):135-46.
Structural Genomics Consortium, China Structural Genomics Consortium, Northeast Structural Genomics Consortium, Gräslund S, Nordlund P, Weigelt J, Hallberg BM, Bray J, Gileadi O, Knapp S, Oppermann U, Arrowsmith C, Hui R, Ming J, dhe-Paganon S, Park HW, Savchenko A, Yee A, Edwards A, Vincentelli R, Cambillau C, Kim R, Kim SH, Rao Z, Shi Y, Terwilliger TC, Kim CY, Hung LW, Waldo GS, Peleg Y, Albeck S, Unger T, Dym O, Prilusky J, Sussman JL, Stevens RC, Lesley SA, Wilson IA, Joachimiak A, Collart F, Dementieva I, Donnelly MI, Eschenfeldt WH, Kim Y, Stols L, Wu R, Zhou M, Burley SK, Emtage JS, Sauder JM, Thompson D, Bain K, Luz J, Gheyi T, Zhang F, Atwell S, Almo SC, Bonanno JB, Fiser A, Swaminathan S, Studier FW, Chance MR, Sali A, Acton TB, Xiao R, Zhao L, Ma LC, Hunt JF, Tong L, Cunningham K, Inouye M, Anderson S, Janjua H, Shastry R, Ho CK, Wang D, Wang H, Jiang M, Montelione GT, Stuart DI, Owens RJ, Daenke S, Schütz A, Heinemann U, Yokoyama S, Büssow K, Gunsalus KC. PMID: 18235434; PMCID: PMC3178102.
View in:
PubMed Mentions:
266 Fields:
-
Integrating diverse data for structure determination of macromolecular assemblies. Annu Rev Biochem. 2008; 77:443-77.
Alber F, Förster F, Korkin D, Topf M, Sali A. PMID: 18318657.
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PubMed Mentions:
102 Fields:
Translation:
HumansAnimalsCells
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Protein structure modeling with MODELLER. Methods Mol Biol. 2008; 426:145-59.
Eswar N, Eramian D, Webb B, Shen MY, Sali A. PMID: 18542861.
View in:
PubMed Mentions:
474 Fields:
Translation:
Cells
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The molecular sociology of the cell. Nature. 2007 Dec 13; 450(7172):973-82.
Robinson CV, Sali A, Baumeister W. PMID: 18075576.
View in:
PubMed Mentions:
195 Fields:
Translation:
HumansCells
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Structural genomics of protein phosphatases. J Struct Funct Genomics. 2007 Sep; 8(2-3):121-40.
Almo SC, Bonanno JB, Sauder JM, Emtage S, Dilorenzo TP, Malashkevich V, Wasserman SR, Swaminathan S, Eswaramoorthy S, Agarwal R, Kumaran D, Madegowda M, Ragumani S, Patskovsky Y, Alvarado J, Ramagopal UA, Faber-Barata J, Chance MR, Sali A, Fiser A, Zhang ZY, Lawrence DS, Burley SK. PMID: 18058037; PMCID: PMC4163028.
View in:
PubMed Mentions:
73 Fields:
Translation:
HumansAnimals
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Stereochemical criteria for prediction of the effects of proline mutations on protein stability. PLoS Comput Biol. 2007 Dec; 3(12):e241.
Bajaj K, Madhusudhan MS, Adkar BV, Chakrabarti P, Ramakrishnan C, Sali A, Varadarajan R. PMID: 18069886; PMCID: PMC2134964.
View in:
PubMed Mentions:
28 Fields:
Translation:
Cells
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Determining the architectures of macromolecular assemblies. Nature. 2007 Nov 29; 450(7170):683-94.
Alber F, Dokudovskaya S, Veenhoff LM, Zhang W, Kipper J, Devos D, Suprapto A, Karni-Schmidt O, Williams R, Chait BT, Rout MP, Sali A. PMID: 18046405.
View in:
PubMed Mentions:
285 Fields:
Translation:
AnimalsCells
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The molecular architecture of the nuclear pore complex. Nature. 2007 Nov 29; 450(7170):695-701.
Alber F, Dokudovskaya S, Veenhoff LM, Zhang W, Kipper J, Devos D, Suprapto A, Karni-Schmidt O, Williams R, Chait BT, Sali A, Rout MP. PMID: 18046406.
View in:
PubMed Mentions:
510 Fields:
Translation:
AnimalsCells
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Comparative protein structure modeling using MODELLER. Curr Protoc Protein Sci. 2007 11; Chapter 2:Unit 2.9.
Eswar N, Webb B, Marti-Renom MA, Madhusudhan MS, Eramian D, Shen MY, Pieper U, Sali A. PMID: 18429317.
View in:
PubMed Mentions:
552 Fields:
Translation:
AnimalsCells
-
Structural genomics. Structure. 2007 Nov; 15(11):1341.
Sali A, Lima CD, Kostic M. PMID: 17997955.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Host pathogen protein interactions predicted by comparative modeling. Protein Sci. 2007 Dec; 16(12):2585-96.
Davis FP, Barkan DT, Eswar N, McKerrow JH, Sali A. PMID: 17965183; PMCID: PMC2222825.
View in:
PubMed Mentions:
60 Fields:
Translation:
HumansCells
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Crystallographic conformers of actin in a biologically active bundle of filaments. J Mol Biol. 2008 Jan 11; 375(2):331-6.
Cong Y, Topf M, Sali A, Matsudaira P, Dougherty M, Chiu W, Schmid MF. PMID: 18022194; PMCID: PMC2680129.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Fold assessment for comparative protein structure modeling. Protein Sci. 2007 Nov; 16(11):2412-26.
Melo F, Sali A. PMID: 17905832; PMCID: PMC2211691.
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PubMed Mentions:
49 Fields:
Translation:
Cells
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Modeling mutations in protein structures. Protein Sci. 2007 Sep; 16(9):2030-41.
Feyfant E, Sali A, Fiser A. PMID: 17766392; PMCID: PMC2206969.
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PubMed Mentions:
28 Fields:
Translation:
Cells
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Characterization of protein hubs by inferring interacting motifs from protein interactions. PLoS Comput Biol. 2007 Sep; 3(9):1761-71.
Aragues R, Sali A, Bonet J, Marti-Renom MA, Oliva B. PMID: 17941705; PMCID: PMC1976338.
View in:
PubMed Mentions:
24 Fields:
Translation:
Cells
-
The AnnoLite and AnnoLyze programs for comparative annotation of protein structures. BMC Bioinformatics. 2007 May 22; 8 Suppl 4:S4.
Marti-Renom MA, Rossi A, Al-Shahrour F, Davis FP, Pieper U, Dopazo J, Sali A. PMID: 17570147; PMCID: PMC1892083.
View in:
PubMed Mentions:
26 Fields:
Translation:
Cells
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DBAli tools: mining the protein structure space. Nucleic Acids Res. 2007 Jul; 35(Web Server issue):W393-7.
Marti-Renom MA, Pieper U, Madhusudhan MS, Rossi A, Eswar N, Davis FP, Al-Shahrour F, Dopazo J, Sali A. PMID: 17478513; PMCID: PMC1933139.
View in:
PubMed Mentions:
15 Fields:
Translation:
Cells
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The structure of chagasin in complex with a cysteine protease clarifies the binding mode and evolution of an inhibitor family. Structure. 2007 May; 15(5):535-43.
Wang SX, Pandey KC, Scharfstein J, Whisstock J, Huang RK, Jacobelli J, Fletterick RJ, Rosenthal PJ, Abrahamson M, Brinen LS, Rossi A, Sali A, McKerrow JH. PMID: 17502099.
View in:
PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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Lack of support for a role for RLIP76 (RALBP1) in response to treatment or predisposition to epilepsy. Epilepsia. 2007 Apr; 48(4):674-83.
Soranzo N, Kelly L, Martinian L, Burley MW, Thom M, Sali A, Kroetz DL, Goldstein DB, Sisodiya SM. PMID: 17437410.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Determination of cancer risk associated with germ line BRCA1 missense variants by functional analysis. Cancer Res. 2007 Feb 15; 67(4):1494-501.
Carvalho MA, Marsillac SM, Karchin R, Manoukian S, Grist S, Swaby RF, Urmenyi TP, Rondinelli E, Silva R, Gayol L, Baumbach L, Sutphen R, Pickard-Brzosowicz JL, Nathanson KL, Sali A, Goldgar D, Couch FJ, Radice P, Monteiro AN. PMID: 17308087; PMCID: PMC2936786.
View in:
PubMed Mentions:
58 Fields:
Translation:
HumansAnimals
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Protein interactions and disease phenotypes in the ABC transporter superfamily. Pac Symp Biocomput. 2007; 51-63.
Kelly L, Karchin R, Sali A. PMID: 17990484.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Functional impact of missense variants in BRCA1 predicted by supervised learning. PLoS Comput Biol. 2007 Feb 16; 3(2):e26.
Karchin R, Monteiro AN, Tavtigian SV, Carvalho MA, Sali A. PMID: 17305420; PMCID: PMC1797820.
View in:
PubMed Mentions:
32 Fields:
Translation:
Cells
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Gene expression profiling of the human maternal-fetal interface reveals dramatic changes between midgestation and term. Endocrinology. 2007 Mar; 148(3):1059-79.
Winn VD, Haimov-Kochman R, Paquet AC, Yang YJ, Madhusudhan MS, Gormley M, Feng KT, Bernlohr DA, McDonagh S, Pereira L, Sali A, Fisher SJ. PMID: 17170095.
View in:
PubMed Mentions:
93 Fields:
Translation:
Humans
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Statistical potential for assessment and prediction of protein structures. Protein Sci. 2006 Nov; 15(11):2507-24.
Shen MY, Sali A. PMID: 17075131; PMCID: PMC2242414.
View in:
PubMed Mentions:
1096 Fields:
Translation:
Cells
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Structural modeling of protein interactions by analogy: application to PSD-95. PLoS Comput Biol. 2006 Nov 10; 2(11):e153.
Korkin D, Davis FP, Alber F, Luong T, Shen MY, Lucic V, Kennedy MB, Sali A. PMID: 17096593; PMCID: PMC1635541.
View in:
PubMed Mentions:
18 Fields:
Translation:
Cells
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Comparative protein structure modeling using Modeller. Curr Protoc Bioinformatics. 2006 Oct; Chapter 5:Unit-5.6.
Eswar N, Webb B, Marti-Renom MA, Madhusudhan MS, Eramian D, Shen MY, Pieper U, Sali A. PMID: 18428767; PMCID: PMC4186674.
View in:
PubMed Mentions:
1231 Fields:
Translation:
Cells
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Localization of binding sites in protein structures by optimization of a composite scoring function. Protein Sci. 2006 Oct; 15(10):2366-80.
Rossi A, Marti-Renom MA, Sali A. PMID: 16963645; PMCID: PMC2242385.
View in:
PubMed Mentions:
10 Fields:
Translation:
Cells
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Minimalist representations and the importance of nearest neighbor effects in protein folding simulations. J Mol Biol. 2006 Nov 03; 363(4):835-57.
Colubri A, Jha AK, Shen MY, Sali A, Berry RS, Sosnick TR, Freed KF. PMID: 16982067.
View in:
PubMed Mentions:
24 Fields:
Translation:
Cells
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Outcome of a workshop on archiving structural models of biological macromolecules. Structure. 2006 Aug; 14(8):1211-7.
Berman HM, Burley SK, Chiu W, Sali A, Adzhubei A, Bourne PE, Bryant SH, Dunbrack RL, Fidelis K, Frank J, Godzik A, Henrick K, Joachimiak A, Heymann B, Jones D, Markley JL, Moult J, Montelione GT, Orengo C, Rossmann MG, Rost B, Saibil H, Schwede T, Standley DM, Westbrook JD. PMID: 16955948.
View in:
PubMed Mentions:
27 Fields:
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A composite score for predicting errors in protein structure models. Protein Sci. 2006 Jul; 15(7):1653-66.
Eramian D, Shen MY, Devos D, Melo F, Sali A, Marti-Renom MA. PMID: 16751606; PMCID: PMC2242555.
View in:
PubMed Mentions:
83 Fields:
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Protein complex compositions predicted by structural similarity. Nucleic Acids Res. 2006; 34(10):2943-52.
Davis FP, Braberg H, Shen MY, Pieper U, Sali A, Madhusudhan MS. PMID: 16738133; PMCID: PMC1474056.
View in:
PubMed Mentions:
26 Fields:
Translation:
Cells
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Protease accessibility laddering: a proteomic tool for probing protein structure. Structure. 2006 Apr; 14(4):653-60.
Dokudovskaya S, Williams R, Devos D, Sali A, Chait BT, Rout MP. PMID: 16615907.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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PharmGKB submission update: IV. PMT submissions of genetic variations in ATP-Binding cassette transporters to the PharmGKB network. Pharmacol Rev. 2006 Mar; 58(1):1-2.
Nguyen TD, Gow JM, Chinn LW, Kelly L, Jeong H, Huang CC, Stryke D, Kawamoto M, Johns SJ, Carlson E, Taylor T, Ferrin TE, Sali A, Giacomini KM, Kroetz DL. PMID: 16507877.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Simple fold composition and modular architecture of the nuclear pore complex. Proc Natl Acad Sci U S A. 2006 Feb 14; 103(7):2172-7.
Devos D, Dokudovskaya S, Williams R, Alber F, Eswar N, Chait BT, Rout MP, Sali A. PMID: 16461911; PMCID: PMC1413685.
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PubMed Mentions:
143 Fields:
Translation:
AnimalsCells
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Refinement of protein structures by iterative comparative modeling and CryoEM density fitting. J Mol Biol. 2006 Apr 14; 357(5):1655-68.
Topf M, Baker ML, Marti-Renom MA, Chiu W, Sali A. PMID: 16490207.
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PubMed Mentions:
56 Fields:
Translation:
Cells
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Variable gap penalty for protein sequence-structure alignment. Protein Eng Des Sel. 2006 Mar; 19(3):129-33.
Madhusudhan MS, Marti-Renom MA, Sanchez R, Sali A. PMID: 16423846.
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PubMed Mentions:
30 Fields:
Translation:
Cells
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MODBASE: a database of annotated comparative protein structure models and associated resources. Nucleic Acids Res. 2006 Jan 01; 34(Database issue):D291-5.
Pieper U, Eswar N, Davis FP, Braberg H, Madhusudhan MS, Rossi A, Marti-Renom M, Karchin R, Webb BM, Eramian D, Shen MY, Kelly L, Melo F, Sali A. PMID: 16381869; PMCID: PMC1347422.
View in:
PubMed Mentions:
108 Fields:
Translation:
HumansCells
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Combining electron microscopy and comparative protein structure modeling. Curr Opin Struct Biol. 2005 Oct; 15(5):578-85.
Topf M, Sali A. PMID: 16118050.
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PubMed Mentions:
29 Fields:
Translation:
Cells
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The C-type lectin fold as an evolutionary solution for massive sequence variation. Nat Struct Mol Biol. 2005 Oct; 12(10):886-92.
McMahon SA, Miller JL, Lawton JA, Kerkow DE, Hodes A, Marti-Renom MA, Doulatov S, Narayanan E, Sali A, Miller JF, Ghosh P. PMID: 16170324.
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PubMed Mentions:
54 Fields:
Translation:
Cells
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Localization of protein-binding sites within families of proteins. Protein Sci. 2005 Sep; 14(9):2350-60.
Korkin D, Davis FP, Sali A. PMID: 16081657; PMCID: PMC2253467.
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PubMed Mentions:
21 Fields:
Translation:
Cells
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Multiple cathepsin B isoforms in schistosomula of Trichobilharzia regenti: identification, characterisation and putative role in migration and nutrition. Int J Parasitol. 2005 Jul; 35(8):895-910.
Dvorák J, Delcroix M, Rossi A, Vopálenský V, Pospísek M, Sedinová M, Mikes L, Sajid M, Sali A, McKerrow JH, Horák P, Caffrey CR. PMID: 15950230.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Detecting remotely related proteins by their interactions and sequence similarity. Proc Natl Acad Sci U S A. 2005 May 17; 102(20):7151-6.
Espadaler J, Aragüés R, Eswar N, Marti-Renom MA, Querol E, Avilés FX, Sali A, Oliva B. PMID: 15883372; PMCID: PMC1129109.
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PubMed Mentions:
9 Fields:
Translation:
Cells
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LS-SNP: large-scale annotation of coding non-synonymous SNPs based on multiple information sources. Bioinformatics. 2005 Jun 15; 21(12):2814-20.
Karchin R, Diekhans M, Kelly L, Thomas DJ, Pieper U, Eswar N, Haussler D, Sali A. PMID: 15827081.
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PubMed Mentions:
103 Fields:
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Structural characterization of assemblies from overall shape and subcomplex compositions. Structure. 2005 Mar; 13(3):435-45.
Alber F, Kim MF, Sali A. PMID: 15766545.
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PubMed Mentions:
10 Fields:
Translation:
Cells
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Urokinase-type plasminogen activator is a preferred substrate of the human epithelium serine protease tryptase epsilon/PRSS22. Blood. 2005 May 15; 105(10):3893-901.
Yasuda S, Morokawa N, Wong GW, Rossi A, Madhusudhan MS, Sali A, Askew YS, Adachi R, Silverman GA, Krilis SA, Stevens RL. PMID: 15701722; PMCID: PMC1895090.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Structural characterization of components of protein assemblies by comparative modeling and electron cryo-microscopy. J Struct Biol. 2005 Feb; 149(2):191-203.
Topf M, Baker ML, John B, Chiu W, Sali A. PMID: 15681235.
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PubMed Mentions:
46 Fields:
Translation:
Cells
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PIBASE: a comprehensive database of structurally defined protein interfaces. Bioinformatics. 2005 May 01; 21(9):1901-7.
Davis FP, Sali A. PMID: 15657096.
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PubMed Mentions:
76 Fields:
Translation:
Cells
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New York-Structural GenomiX Research Consortium (NYSGXRC): a large scale center for the protein structure initiative. J Struct Funct Genomics. 2005; 6(2-3):225-32.
Bonanno JB, Almo SC, Bresnick A, Chance MR, Fiser A, Swaminathan S, Jiang J, Studier FW, Shapiro L, Lima CD, Gaasterland TM, Sali A, Bain K, Feil I, Gao X, Lorimer D, Ramos A, Sauder JM, Wasserman SR, Emtage S, D'Amico KL, Burley SK. PMID: 16211523.
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PubMed Mentions:
19 Fields:
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Improving functional annotation of non-synonomous SNPs with information theory. Pac Symp Biocomput. 2005; 397-408.
Karchin R, Kelly L, Sali A. PMID: 15759645.
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PubMed Mentions:
17 Fields:
Translation:
Cells
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Finding cures for tropical diseases: is open source an answer? PLoS Med. 2004 Dec; 1(3):e56.
Maurer SM, Rai A, Sali A. PMID: 15630466; PMCID: PMC539047.
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PubMed Mentions:
21 Fields:
Translation:
Humans
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Components of coated vesicles and nuclear pore complexes share a common molecular architecture. PLoS Biol. 2004 Dec; 2(12):e380.
Devos D, Dokudovskaya S, Alber F, Williams R, Chait BT, Sali A, Rout MP. PMID: 15523559; PMCID: PMC524472.
View in:
PubMed Mentions:
193 Fields:
Translation:
AnimalsCells
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High-throughput computational and experimental techniques in structural genomics. Genome Res. 2004 Oct; 14(10B):2145-54.
Chance MR, Fiser A, Sali A, Pieper U, Eswar N, Xu G, Fajardo JE, Radhakannan T, Marinkovic N. PMID: 15489337; PMCID: PMC528931.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Structure-based assessment of missense mutations in human BRCA1: implications for breast and ovarian cancer predisposition. Cancer Res. 2004 Jun 01; 64(11):3790-7.
Mirkovic N, Marti-Renom MA, Weber BL, Sali A, Monteiro AN. PMID: 15172985.
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PubMed Mentions:
47 Fields:
Translation:
HumansCells
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A structural perspective on protein-protein interactions. Curr Opin Struct Biol. 2004 Jun; 14(3):313-24.
Russell RB, Alber F, Aloy P, Davis FP, Korkin D, Pichaud M, Topf M, Sali A. PMID: 15193311.
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PubMed Mentions:
80 Fields:
Translation:
HumansAnimalsCells
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Comprehensive search for cysteine cathepsins in the human genome. Biol Chem. 2004 May; 385(5):363-72.
Rossi A, Deveraux Q, Turk B, Sali A. PMID: 15195995.
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PubMed Mentions:
50 Fields:
Translation:
Humans
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Alignment of protein sequences by their profiles. Protein Sci. 2004 Apr; 13(4):1071-87.
Marti-Renom MA, Madhusudhan MS, Sali A. PMID: 15044736; PMCID: PMC2280052.
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PubMed Mentions:
81 Fields:
Translation:
Cells
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Detection of homologous proteins by an intermediate sequence search. Protein Sci. 2004 Jan; 13(1):54-62.
John B, Sali A. PMID: 14691221; PMCID: PMC2286512.
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PubMed Mentions:
11 Fields:
Translation:
Cells
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MODBASE, a database of annotated comparative protein structure models, and associated resources. Nucleic Acids Res. 2004 Jan 01; 32(Database issue):D217-22.
Pieper U, Eswar N, Braberg H, Madhusudhan MS, Davis FP, Stuart AC, Mirkovic N, Rossi A, Marti-Renom MA, Fiser A, Webb B, Greenblatt D, Huang CC, Ferrin TE, Sali A. PMID: 14681398; PMCID: PMC308829.
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PubMed Mentions:
87 Fields:
Translation:
HumansAnimalsCells
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ModLoop: automated modeling of loops in protein structures. Bioinformatics. 2003 Dec 12; 19(18):2500-1.
Fiser A, Sali A. PMID: 14668246.
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PubMed Mentions:
314 Fields:
Translation:
Cells
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NIH workshop on structural proteomics of biological complexes. Structure. 2003 Sep; 11(9):1043-7.
Sali A. PMID: 12962622.
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PubMed Mentions:
4 Fields:
Translation:
Cells
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Comparative protein structure modeling by iterative alignment, model building and model assessment. Nucleic Acids Res. 2003 Jul 15; 31(14):3982-92.
John B, Sali A. PMID: 12853614; PMCID: PMC165975.
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PubMed Mentions:
122 Fields:
Translation:
Cells
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EVA: Evaluation of protein structure prediction servers. Nucleic Acids Res. 2003 Jul 01; 31(13):3311-5.
Koh IY, Eyrich VA, Marti-Renom MA, Przybylski D, Madhusudhan MS, Eswar N, Graña O, Pazos F, Valencia A, Sali A, Rost B. PMID: 12824315; PMCID: PMC169025.
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PubMed Mentions:
43 Fields:
Translation:
Cells
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Tools for comparative protein structure modeling and analysis. Nucleic Acids Res. 2003 Jul 01; 31(13):3375-80.
Eswar N, John B, Mirkovic N, Fiser A, Ilyin VA, Pieper U, Stuart AC, Marti-Renom MA, Madhusudhan MS, Yerkovich B, Sali A. PMID: 12824331; PMCID: PMC168950.
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PubMed Mentions:
202 Fields:
Translation:
Cells
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Study of the structural dynamics of the E coli 70S ribosome using real-space refinement. Cell. 2003 Jun 13; 113(6):789-801.
Gao H, Sengupta J, Valle M, Korostelev A, Eswar N, Stagg SM, Van Roey P, Agrawal RK, Harvey SC, Sali A, Chapman MS, Frank J. PMID: 12809609.
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PubMed Mentions:
110 Fields:
Translation:
Cells
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The zebrafish forkhead transcription factor Foxi1 specifies epibranchial placode-derived sensory neurons. Development. 2003 Jun; 130(12):2669-79.
Lee SA, Shen EL, Fiser A, Sali A, Guo S. PMID: 12736211.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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From words to literature in structural proteomics. Nature. 2003 Mar 13; 422(6928):216-25.
Sali A, Glaeser R, Earnest T, Baumeister W. PMID: 12634795.
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PubMed Mentions:
111 Fields:
Translation:
HumansAnimalsCells
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Modeller: generation and refinement of homology-based protein structure models. Methods Enzymol. 2003; 374:461-91.
Fiser A, Sali A. PMID: 14696385.
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PubMed Mentions:
725 Fields:
Translation:
AnimalsCells
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ModView, visualization of multiple protein sequences and structures. Bioinformatics. 2003 Jan; 19(1):165-6.
Ilyin VA, Pieper U, Stuart AC, Marti-Renom MA, McMahan L, Sali A. PMID: 12499313.
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PubMed Mentions:
5 Fields:
Translation:
Cells
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Use of single point mutations in domain I of beta 2-glycoprotein I to determine fine antigenic specificity of antiphospholipid autoantibodies. J Immunol. 2002 Dec 15; 169(12):7097-103.
Iverson GM, Reddel S, Victoria EJ, Cockerill KA, Wang YX, Marti-Renom MA, Sali A, Marquis DM, Krilis SA, Linnik MD. PMID: 12471146.
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PubMed Mentions:
30 Fields:
Translation:
HumansCells
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Evolution and physics in comparative protein structure modeling. Acc Chem Res. 2002 Jun; 35(6):413-21.
Fiser A, Feig M, Brooks CL, Sali A. PMID: 12069626.
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PubMed Mentions:
29 Fields:
Translation:
Cells
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Probing the specificity of a trypanosomal aromatic alpha-hydroxy acid dehydrogenase by site-directed mutagenesis. Biochem Biophys Res Commun. 2002 Apr 26; 293(1):633-9.
Vernal J, Fiser A, Sali A, Müller M, Cazzulo JJ, Nowicki C. PMID: 12054650.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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RasGRP4, a new mast cell-restricted Ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs. Identification of defective variants of this signaling protein in asthma, mastocytosis, and mast cell leukemia patients and demonstration of the importance of RasGRP4 in mast cell development and function. J Biol Chem. 2002 Jul 12; 277(28):25756-74.
Yang Y, Li L, Wong GW, Krilis SA, Madhusudhan MS, Sali A, Stevens RL. PMID: 11956218.
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PubMed Mentions:
44 Fields:
Translation:
HumansAnimalsCells
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Structural genomics: a pipeline for providing structures for the biologist. Protein Sci. 2002 Apr; 11(4):723-38.
Chance MR, Bresnick AR, Burley SK, Jiang JS, Lima CD, Sali A, Almo SC, Bonanno JB, Buglino JA, Boulton S, Chen H, Eswar N, He G, Huang R, Ilyin V, McMahan L, Pieper U, Ray S, Vidal M, Wang LK. PMID: 11910018; PMCID: PMC2373525.
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PubMed Mentions:
56 Fields:
Translation:
HumansAnimalsCells
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Reliability of assessment of protein structure prediction methods. Structure. 2002 Mar; 10(3):435-40.
Marti-Renom MA, Madhusudhan MS, Fiser A, Rost B, Sali A. PMID: 12005441.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansCells
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Statistical potentials for fold assessment. Protein Sci. 2002 Feb; 11(2):430-48.
Melo F, Sánchez R, Sali A. PMID: 11790853; PMCID: PMC2373452.
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PubMed Mentions:
155 Fields:
Translation:
Cells
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LigBase: a database of families of aligned ligand binding sites in known protein sequences and structures. Bioinformatics. 2002 Jan; 18(1):200-1.
Stuart AC, Ilyin VA, Sali A. PMID: 11836232.
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PubMed Mentions:
29 Fields:
Translation:
Cells
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MODBASE, a database of annotated comparative protein structure models. Nucleic Acids Res. 2002 Jan 01; 30(1):255-9.
Pieper U, Eswar N, Stuart AC, Ilyin VA, Sali A. PMID: 11752309; PMCID: PMC99112.
View in:
PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells