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Andrew Jheon, PhD, DDS

Title(s)Assistant Professor, Orofacial Sciences
SchoolSchool of Dentistry
Address513 Parnassus Ave, HSW
San Francisco CA 94143
Phone415-502-2730
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPostdoctoral StudiesGraduate Division

    Collapse Research 
    Collapse Research Activities and Funding
    Temporal inactivation of epithelial Isl1 in adult mice leads to incisor enamel defects
    NIH/NIDCR R03DE026709Jan 1, 2018 - Dec 31, 2019
    Role: Principal Investigator
    NIDCR Dentist Scientist K99;Function and Regulation of Perp in Amelogenesis
    NIH/NIDCR R00DE022059Aug 20, 2013 - Jul 31, 2018
    Role: Principal Investigator
    NIDCR Dentist Scientist K99;Function and Regulation of Perp in Amelogenesis
    NIH/NIDCR K99DE022059Jul 13, 2011 - Jun 30, 2013
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Effects of Multi-Generational Soft Diet Consumption on Mouse Craniofacial Morphology. Front Physiol. 2020; 11:783. Hassan MG, Kaler H, Zhang B, Cox TC, Young N, Jheon AH. PMID: 32754047.
      View in: PubMed   Mentions:
    2. Comparative analysis of clinical characteristics, imaging and laboratory findings of different age groups with COVID-19. Indian J Med Microbiol. 2020 Jan-Mar; 38(1):87-93. Liu X, Lv J, Gan L, Zhang Y, Sun F, Meng B, Jheon A, Yan F, Li B, Xuan Z, Ma X, Wulasihana M. PMID: 32719214.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    3. Downregulation of FGF Signaling by Spry4 Overexpression Leads to Shape Impairment, Enamel Irregularities, and Delayed Signaling Center Formation in the Mouse Molar. JBMR Plus. 2019 Aug; 3(8):e10205. Marangoni P, Charles C, Ahn Y, Seidel K, Jheon A, Ganss B, Krumlauf R, Viriot L, Klein OD. PMID: 31485553.
      View in: PubMed   Mentions:
    4. Altering calcium and phosphorus levels in utero affects adult mouse mandibular morphology. Orthod Craniofac Res. 2019 May; 22 Suppl 1:113-119. Hassan MG, Vargas R, Zaher AR, Ismail HA, Lee C, Cox TC, Jheon AH. PMID: 31074150.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    5. Microanatomical changes and biomolecular expression at the PDL-entheses during experimental tooth movement. J Periodontal Res. 2019 Jun; 54(3):251-258. Yang L, Kang M, He R, Meng B, Pal A, Chen L, Jheon AH, Ho SP. PMID: 30485431.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    6. The Role of Epithelial Stat3 in Amelogenesis during Mouse Incisor Renewal. Cells Tissues Organs. 2018; 205(2):63-71. Zhang B, Meng B, Viloria E, Naveau A, Ganss B, Jheon AH. PMID: 29550820.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    7. Isl1 Controls Patterning and Mineralization of Enamel in the Continuously Renewing Mouse Incisor. J Bone Miner Res. 2017 Nov; 32(11):2219-2231. Naveau A, Zhang B, Meng B, Sutherland MT, Prochazkova M, Wen T, Marangoni P, Jones KB, Cox TC, Ganss B, Jheon AH, Klein OD. PMID: 28650075.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    8. Ras Signaling Regulates Stem Cells and Amelogenesis in the Mouse Incisor. J Dent Res. 2017 Nov; 96(12):1438-1444. Zheng X, Goodwin AF, Tian H, Jheon AH, Klein OD. PMID: 28644741.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    9. Micro-anatomical responses in periodontal complexes of mice to calibrated orthodontic forces on the crown. Orthod Craniofac Res. 2017 Jun; 20 Suppl 1:100-105. Pal A, Chen L, Yang L, Yang F, Meng B, Jheon AH, Ho SP. PMID: 28643923.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    10. Moving towards precision orthodontics: An evolving paradigm shift in the planning and delivery of customized orthodontic therapy. Orthod Craniofac Res. 2017 Jun; 20 Suppl 1:106-113. Jheon AH, Oberoi S, Solem RC, Kapila S. PMID: 28643930.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    11. FGF signaling refines Wnt gradients to regulate the patterning of taste papillae. Development. 2017 06 15; 144(12):2212-2221. Prochazkova M, Häkkinen TJ, Prochazka J, Spoutil F, Jheon AH, Ahn Y, Krumlauf R, Jernvall J, Klein OD. PMID: 28506989.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    12. Neural crest-mediated bone resorption is a determinant of species-specific jaw length. Dev Biol. 2015 Dec 01; 408(1):151-63. Ealba EL, Jheon AH, Hall J, Curantz C, Butcher KD, Schneider RA. PMID: 26449912.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    13. Inhibition of Notch Signaling During Mouse Incisor Renewal Leads to Enamel Defects. J Bone Miner Res. 2016 Jan; 31(1):152-62. Jheon AH, Prochazkova M, Meng B, Wen T, Lim YJ, Naveau A, Espinoza R, Cox TC, Sone ED, Ganss B, Siebel CW, Klein OD. PMID: 26179131.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    14. Spontaneous emergence of overgrown molar teeth in a colony of Prairie voles (Microtus ochrogaster). Int J Oral Sci. 2015 Mar 23; 7(1):23-6. Jheon AH, Prochazkova M, Sherman M, Manoli DS, Shah NM, Carbone L, Klein O. PMID: 25634121.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    15. Craniofacial morphometric analysis of individuals with X-linked hypohidrotic ectodermal dysplasia. Mol Genet Genomic Med. 2014 Sep; 2(5):422-9. Goodwin AF, Larson JR, Jones KB, Liberton DK, Landan M, Wang Z, Boekelheide A, Langham M, Mushegyan V, Oberoi S, Brao R, Wen T, Johnson R, Huttner K, Grange DK, Spritz RA, Hallgrímsson B, Jheon AH, Klein OD. PMID: 25333067.
      View in: PubMed   Mentions: 5     Fields:    
    16. Isolation and culture of dental epithelial stem cells from the adult mouse incisor. J Vis Exp. 2014 May 01; (87). Chavez MG, Hu J, Seidel K, Li C, Jheon A, Naveau A, Horst O, Klein OD. PMID: 24834972.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    17. The society of craniofacial genetics and developmental biology 35th annual meeting. American Journal of Medical Genetics Part A. 2013 Dec 1; 161(12):2938-2952. Ophir D. Klein, Jeffrey O. Bush, Sarah M. Knox, Andrew H. Jheon, Dwight R. Cordero, Joan T. Richtsmeier. .
      View in: Publisher Site   Mentions:
    18. Evolution of a developmental mechanism: Species-specific regulation of the cell cycle and the timing of events during craniofacial osteogenesis. Dev Biol. 2014 Jan 15; 385(2):380-95. Hall J, Jheon AH, Ealba EL, Eames BF, Butcher KD, Mak SS, Ladher R, Alliston T, Schneider RA. PMID: 24262986.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    19. Abnormal Ras signaling in Costello syndrome (CS) negatively regulates enamel formation. Hum Mol Genet. 2014 Feb 01; 23(3):682-92. Goodwin AF, Tidyman WE, Jheon AH, Sharir A, Zheng X, Charles C, Fagin JA, McMahon M, Diekwisch TG, Ganss B, Rauen KA, Klein OD. PMID: 24057668.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    20. The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation. Development. 2013 Aug; 140(16):3348-59. Cao H, Jheon A, Li X, Sun Z, Wang J, Florez S, Zhang Z, McManus MT, Klein OD, Amendt BA. PMID: 23863486.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    21. Characterization of X-linked hypohidrotic ectodermal dysplasia (XL-HED) hair and sweat gland phenotypes using phototrichogram analysis and live confocal imaging. Am J Med Genet A. 2013 Jul; 161A(7):1585-93. Jones KB, Goodwin AF, Landan M, Seidel K, Tran DK, Hogue J, Chavez M, Fete M, Yu W, Hussein T, Johnson R, Huttner K, Jheon AH, Klein OD. PMID: 23687000.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. The Pitx2:miR-200 Family Axis Regulates WNT and BMP Signaling During Tooth Morphogenesis and Renewal. The FASEB Journal. 2013 Apr 1; 27:193.1-193.1. Xiao Li, Huojun Cao, Andrew Jheon, Zhao Sun, Jianbo Wang, Ophir Klein, Brad A Amendt. .
      View in: Publisher Site   Mentions:
    23. Essential Genes in the Development and Maintenance of the Temporomandibular Joint. The FASEB Journal. 2013 Apr 1; 27:319.5-319.5. Patricia Purcell, Adele Hill, Andrew Jheon, Matthew Vivero, Juanita Duran, Clifford J Tabin, Ophir D Klein, Matthew L Warman. .
      View in: Publisher Site   Mentions:
    24. An Incisive Look at Stem Cells: The Mouse Incisor as an Emerging Model for Tooth Renewal. Stem Cells in Craniofacial Development and Regeneration. 2013 Mar 22; 315-327. Frederic Michon, Andrew H. Jheon, Kerstin Seidel, Ophir D. Klein. .
      View in: Publisher Site   Mentions:
    25. Stem cell and biomaterials research in dental tissue engineering and regeneration. Dent Clin North Am. 2012 Jul; 56(3):495-520. Horst OV, Chavez MG, Jheon AH, Desai T, Klein OD. PMID: 22835534.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    26. From molecules to mastication: the development and evolution of teeth. Wiley Interdiscip Rev Dev Biol. 2013 Mar-Apr; 2(2):165-82. Jheon AH, Seidel K, Biehs B, Klein OD. PMID: 24009032.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    27. Regulation of Jaw Size During Development and Evolution. The FASEB Journal. 2012 Apr 1; 26:457.5-457.5. Erin L Ealba, Jane Yu, Andrew H Jheon, Kristin D Butcher, Richard A Schneider. .
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    28. Spry1 and spry2 are essential for development of the temporomandibular joint. J Dent Res. 2012 Apr; 91(4):387-93. Purcell P, Jheon A, Vivero MP, Rahimi H, Joo A, Klein OD. PMID: 22328578.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    29. Expression of microRNAs in the stem cell niche of the adult mouse incisor. PLoS One. 2011; 6(9):e24536. Jheon AH, Li CY, Wen T, Michon F, Klein OD. PMID: 21931743.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    30. Regulation of tooth number by fine-tuning levels of receptor-tyrosine kinase signaling. Development. 2011 Sep; 138(18):4063-73. Charles C, Hovorakova M, Ahn Y, Lyons DB, Marangoni P, Churava S, Biehs B, Jheon A, Lesot H, Balooch G, Krumlauf R, Viriot L, Peterkova R, Klein OD. PMID: 21862563.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    31. FGF signaling regulates the number of posterior taste papillae by controlling progenitor field size. PLoS Genet. 2011 Jun; 7(6):e1002098. Petersen CI, Jheon AH, Mostowfi P, Charles C, Ching S, Thirumangalathu S, Barlow LA, Klein OD. PMID: 21655085.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    32. Neural crest-mediated Runx2 expression regulates the development and evolution of the avian beak. The FASEB Journal. 2011 Apr 1; 25:302.2-302.2. Jane Yu, Andrew H Jheon, Brian F Eames, Erin Ealba, Kristin Butcher, Richard A Schneider. .
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    33. PERP regulates enamel formation via effects on cell-cell adhesion and gene expression. J Cell Sci. 2011 Mar 01; 124(Pt 5):745-54. Jheon AH, Mostowfi P, Snead ML, Ihrie RA, Sone E, Pramparo T, Attardi LD, Klein OD. PMID: 21285247.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    34. Mesenchymal regulation of vascular invasion and matrix remodeling during intramembranous ossification. Developmental Biology. 2009 Jul 1; 331(2):459. Erin A. Ealba, A.H. Jheon, K.D. Butcher, F.J. Smith, R.A. Schneider. .
      View in: Publisher Site   Mentions:
    35. Mesenchymal regulation of mineralization and bone mineral density in the jaw skeleton. Developmental Biology. 2009 Jul 1; 331(2):459. Jane A. Yu, A.H. Jheon, B.F. Eames, R.A. Schneider. .
      View in: Publisher Site   Mentions:
    36. Characterisation of the constitutive over-expression of AJ18 in a novel rat stromal bone marrow cell line (D8-SBMC). Arch Oral Biol. 2009 Aug; 54(8):705-16. Jheon A, Bansal AK, Zhu B, Ganss B, Cheifetz S, Sodek J. PMID: 19473652.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    37. Mesenchymal regulation of mineralization and bone mineral density in the jaw skeleton. The FASEB Journal. 2009 Apr 1; 23:180.4-180.4. Jane Yu, Andrew H. Jheon, Brian F. Eames, Richard A. Schneider. .
      View in: Publisher Site   Mentions:
    38. Mesenchymal regulation of vascular invasion and matrix remodeling during intramembranous ossification. The FASEB Journal. 2009 Apr 1; 23:646.2-646.2. Kristin D. Butcher, Andrew H. Jheon, Francis J. Smith, Richard A. Schneider. .
      View in: Publisher Site   Mentions:
    39. The cells that fill the bill: neural crest and the evolution of craniofacial development. J Dent Res. 2009 Jan; 88(1):12-21. Jheon AH, Schneider RA. PMID: 19131312.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    40. Bones and Cartilage: Developmental and Evolutionary Skeletal Biology. Acta Zoologica. 2008 Jul 1; 89(3):277-278. Andrew H. Jheon, Christian Mitgutsch. .
      View in: Publisher Site   Mentions:
    41. Local and systemic mechanisms controlling osteogenesis. Developmental Biology. 2006 Jul 1; 295(1):400-401. Andrew H. Jheon, Brian F. Eames, Richard A. Schneider. .
      View in: Publisher Site   Mentions:
    42. Molecular cloning, structure, expression, and chromosomal localization of the human Osterix (SP7) gene. Gene. 2004 Oct 27; 341:101-10. Gao Y, Jheon A, Nourkeyhani H, Kobayashi H, Ganss B. PMID: 15474293.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    43. Zinc finger transcription factors in skeletal development. Crit Rev Oral Biol Med. 2004 Sep 01; 15(5):282-97. Ganss B, Jheon A. PMID: 15470266.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    44. The immune regulatory protein B7-H3 promotes osteoblast differentiation and bone mineralization. Proc Natl Acad Sci U S A. 2004 Aug 31; 101(35):12969-73. Suh WK, Wang SX, Jheon AH, Moreno L, Yoshinaga SK, Ganss B, Sodek J, Grynpas MD, Mak TW. PMID: 15317945.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    45. Characterization of the 5'-flanking region of the rat AJ18 gene. Gene. 2003 May 22; 310:203-13. Jheon AH, Suzuki N, Nishiyama T, Cheifetz S, Sodek J, Ganss B. PMID: 12801648.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    46. An L1 element disrupts human bone sialoprotein promoter: lack of tissue-specific regulation by distalless5 (Dlx5) and runt homeodomain protein2 (Runx2)/core binding factor a1 (Cbfa1) elements. Gene. 2002 Oct 16; 299(1-2):205-17. Kiyoshima T, Yamauchi M, Wong C, Jheon A, Ganss B, Sodek J. PMID: 12459268.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    47. Temporal and spatial expression of a novel zinc finger transcription factor, AJ18, in developing murine skeletal tissues. J Histochem Cytochem. 2002 Jul; 50(7):973-82. Jheon A, Chen J, Teo W, Ganss B, Sodek J, Cheifetz S. PMID: 12070276.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    48. Characterization of a novel KRAB/C2H2 zinc finger transcription factor involved in bone development. J Biol Chem. 2001 May 25; 276(21):18282-9. Jheon AH, Ganss B, Cheifetz S, Sodek J. PMID: 11278774.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
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