Andrew Jheon, PhD, DDS

Title(s)Associate Professor, Orofacial Sciences
SchoolSchool of Dentistry
Address513 Parnassus Ave, HSW, #815
San Francisco CA 94143
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    University of California, San FranciscoPostdoctoral StudiesGraduate Division

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    Context dependent roles of Isl1 during mouse incisor renewal
    NIH R56DE029455Sep 14, 2020 - Aug 31, 2021
    Role: Principal Investigator
    Temporal inactivation of epithelial Isl1 in adult mice leads to incisor enamel defects
    NIH R03DE026709Jan 1, 2018 - Dec 31, 2020
    Role: Principal Investigator
    NIDCR Dentist Scientist K99;Function and Regulation of Perp in Amelogenesis
    NIH R00DE022059Aug 20, 2013 - Jul 31, 2019
    Role: Principal Investigator
    NIDCR Dentist Scientist K99;Function and Regulation of Perp in Amelogenesis
    NIH K99DE022059Jul 13, 2011 - Aug 19, 2013
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Sex differences and risk factors for bleeding in Alagille syndrome. EMBO Mol Med. 2022 Dec 07; 14(12):e15809. Hankeova S, Van Hul N, Laznovsky J, Verboven E, Mangold K, Hensens N, Adori C, Verhoef E, Zikmund T, Dawit F, Kavkova M, Salplachta J, Sjöqvist M, Johansson BR, Hassan MG, Fredriksson L, Baumgärtel K, Bryja V, Lendahl U, Jheon A, Alten F, Fahnehjelm KT, Fischler B, Kaiser J, Andersson ER. PMID: 36345711.
      View in: PubMed   Mentions:    Fields:    
    2. Altering osteoclast numbers using CTSK models in utero affects mice offspring craniofacial morphology. Orthod Craniofac Res. 2022 Oct 17. Hassan MG, Vargas R, Zhang B, Marcel N, Cox TC, Jheon AH. PMID: 36245435.
      View in: PubMed   Mentions:    Fields:    
    3. Unilateral Loss of Maxillary Molars in Young Mice Leads to Bilateral Condylar Adaptation and Degenerative Disease. JBMR Plus. 2022 Jul; 6(7):e10638. Chen CP, Zhang J, Zhang B, Hassan MG, Hane K, Chen CC, Navarro Palacios AA, Kapila S, Jheon AH, Goodwin AF. PMID: 35866152; PMCID: PMC9289985.
      View in: PubMed   Mentions:
    4. Standardization of mineral density maps of physiologic and pathologic biominerals in humans using cone-beam CT and micro-CT scanners. Dent Mater. 2022 06; 38(6):989-1003. Srirangapatanam S, Kang M, Ellenikiotis Y, Jheon A, Kapila S, Swana HS, Stoller ML, Seo Y, Ho SP. PMID: 35428494.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Altering calcium and phosphorus supplementation in pregnancy and lactation affects offspring craniofacial morphology in a sex-specific pattern. Am J Orthod Dentofacial Orthop. 2022 May; 161(5):e446-e455. Hassan MG, Chen C, Ismail HA, Zaher AR, Cox TC, Goodwin AF, Jheon AH. PMID: 35131118; PMCID: PMC9202736.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    6. Alterations in subgingival microbiota during full-fixed appliance orthodontic treatment-A prospective study. Orthod Craniofac Res. 2022 May; 25(2):260-268. Chen I, Chung J, Vella R, Weinstock GM, Zhou Y, Jheon AH. PMID: 34538018.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    7. IGF-1 TMJ injections enhance mandibular growth and bone quality in juvenile rats. Orthod Craniofac Res. 2022 May; 25(2):183-191. Joshi AS, Hatch NE, Hayami T, Jheon A, Kapila S. PMID: 34324793; PMCID: PMC8799756.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    8. Effects of Multi-Generational Soft Diet Consumption on Mouse Craniofacial Morphology. Front Physiol. 2020; 11:783. Hassan MG, Kaler H, Zhang B, Cox TC, Young N, Jheon AH. PMID: 32754047; PMCID: PMC7367031.
      View in: PubMed   Mentions: 6  
    9. Comparative analysis of clinical characteristics, imaging and laboratory findings of different age groups with COVID-19. Indian J Med Microbiol. 2020 Jan-Mar; 38(1):87-93. Liu X, Lv J, Gan L, Zhang Y, Sun F, Meng B, Jheon A, Yan F, Li B, Xuan Z, Ma X, Wulasihana M. PMID: 32719214; PMCID: PMC7706422.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCellsPHPublic Health
    10. Downregulation of FGF Signaling by Spry4 Overexpression Leads to Shape Impairment, Enamel Irregularities, and Delayed Signaling Center Formation in the Mouse Molar. JBMR Plus. 2019 Aug; 3(8):e10205. Marangoni P, Charles C, Ahn Y, Seidel K, Jheon A, Ganss B, Krumlauf R, Viriot L, Klein OD. PMID: 31485553; PMCID: PMC6715786.
      View in: PubMed   Mentions: 1  
    11. Altering calcium and phosphorus levels in utero affects adult mouse mandibular morphology. Orthod Craniofac Res. 2019 May; 22 Suppl 1:113-119. Hassan MG, Vargas R, Zaher AR, Ismail HA, Lee C, Cox TC, Jheon AH. PMID: 31074150.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    12. Microanatomical changes and biomolecular expression at the PDL-entheses during experimental tooth movement. J Periodontal Res. 2019 Jun; 54(3):251-258. Yang L, Kang M, He R, Meng B, Pal A, Chen L, Jheon AH, Ho SP. PMID: 30485431; PMCID: PMC6465084.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    13. The Role of Epithelial Stat3 in Amelogenesis during Mouse Incisor Renewal. Cells Tissues Organs. 2018; 205(2):63-71. Zhang B, Meng B, Viloria E, Naveau A, Ganss B, Jheon AH. PMID: 29550820; PMCID: PMC6023741.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    14. Isl1 Controls Patterning and Mineralization of Enamel in the Continuously Renewing Mouse Incisor. J Bone Miner Res. 2017 Nov; 32(11):2219-2231. Naveau A, Zhang B, Meng B, Sutherland MT, Prochazkova M, Wen T, Marangoni P, Jones KB, Cox TC, Ganss B, Jheon AH, Klein OD. PMID: 28650075; PMCID: PMC5685895.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    15. Ras Signaling Regulates Stem Cells and Amelogenesis in the Mouse Incisor. J Dent Res. 2017 Nov; 96(12):1438-1444. Zheng X, Goodwin AF, Tian H, Jheon AH, Klein OD. PMID: 28644741; PMCID: PMC5652855.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    16. Micro-anatomical responses in periodontal complexes of mice to calibrated orthodontic forces on the crown. Orthod Craniofac Res. 2017 Jun; 20 Suppl 1:100-105. Pal A, Chen L, Yang L, Yang F, Meng B, Jheon AH, Ho SP. PMID: 28643923.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    17. Moving towards precision orthodontics: An evolving paradigm shift in the planning and delivery of customized orthodontic therapy. Orthod Craniofac Res. 2017 Jun; 20 Suppl 1:106-113. Jheon AH, Oberoi S, Solem RC, Kapila S. PMID: 28643930.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    18. FGF signaling refines Wnt gradients to regulate the patterning of taste papillae. Development. 2017 06 15; 144(12):2212-2221. Prochazkova M, Häkkinen TJ, Prochazka J, Spoutil F, Jheon AH, Ahn Y, Krumlauf R, Jernvall J, Klein OD. PMID: 28506989; PMCID: PMC5482992.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    19. Neural crest-mediated bone resorption is a determinant of species-specific jaw length. Dev Biol. 2015 Dec 01; 408(1):151-63. Ealba EL, Jheon AH, Hall J, Curantz C, Butcher KD, Schneider RA. PMID: 26449912; PMCID: PMC4698309.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    20. Inhibition of Notch Signaling During Mouse Incisor Renewal Leads to Enamel Defects. J Bone Miner Res. 2016 Jan; 31(1):152-62. Jheon AH, Prochazkova M, Meng B, Wen T, Lim YJ, Naveau A, Espinoza R, Cox TC, Sone ED, Ganss B, Siebel CW, Klein OD. PMID: 26179131; PMCID: PMC4840178.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    21. Spontaneous emergence of overgrown molar teeth in a colony of Prairie voles (Microtus ochrogaster). Int J Oral Sci. 2015 Mar 23; 7(1):23-6. Jheon AH, Prochazkova M, Sherman M, Manoli DS, Shah NM, Carbone L, Klein O. PMID: 25634121; PMCID: PMC4817538.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    22. Craniofacial morphometric analysis of individuals with X-linked hypohidrotic ectodermal dysplasia. Mol Genet Genomic Med. 2014 Sep; 2(5):422-9. Goodwin AF, Larson JR, Jones KB, Liberton DK, Landan M, Wang Z, Boekelheide A, Langham M, Mushegyan V, Oberoi S, Brao R, Wen T, Johnson R, Huttner K, Grange DK, Spritz RA, Hallgrímsson B, Jheon AH, Klein OD. PMID: 25333067; PMCID: PMC4190877.
      View in: PubMed   Mentions: 8     Fields:    
    23. Isolation and culture of dental epithelial stem cells from the adult mouse incisor. J Vis Exp. 2014 May 01; (87). Chavez MG, Hu J, Seidel K, Li C, Jheon A, Naveau A, Horst O, Klein OD. PMID: 24834972; PMCID: PMC4141628.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    24. The society of craniofacial genetics and developmental biology 35th annual meeting. American Journal of Medical Genetics Part A. 2013 Dec 1; 161(12):2938-2952. Klein KO, Bush BJ, Knox KS, Jheon JA, Cordero CD, Richtsmeier RJ. .
      View in: Publisher Site   Mentions:
    25. Evolution of a developmental mechanism: Species-specific regulation of the cell cycle and the timing of events during craniofacial osteogenesis. Dev Biol. 2014 Jan 15; 385(2):380-95. Hall J, Jheon AH, Ealba EL, Eames BF, Butcher KD, Mak SS, Ladher R, Alliston T, Schneider RA. PMID: 24262986; PMCID: PMC3953612.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    26. Abnormal Ras signaling in Costello syndrome (CS) negatively regulates enamel formation. Hum Mol Genet. 2014 Feb 01; 23(3):682-92. Goodwin AF, Tidyman WE, Jheon AH, Sharir A, Zheng X, Charles C, Fagin JA, McMahon M, Diekwisch TG, Ganss B, Rauen KA, Klein OD. PMID: 24057668; PMCID: PMC3888259.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    27. The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation. Development. 2013 Aug; 140(16):3348-59. Cao H, Jheon A, Li X, Sun Z, Wang J, Florez S, Zhang Z, McManus MT, Klein OD, Amendt BA. PMID: 23863486; PMCID: PMC3737717.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    28. Characterization of X-linked hypohidrotic ectodermal dysplasia (XL-HED) hair and sweat gland phenotypes using phototrichogram analysis and live confocal imaging. Am J Med Genet A. 2013 Jul; 161A(7):1585-93. Jones KB, Goodwin AF, Landan M, Seidel K, Tran DK, Hogue J, Chavez M, Fete M, Yu W, Hussein T, Johnson R, Huttner K, Jheon AH, Klein OD. PMID: 23687000; PMCID: PMC4414120.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    29. The Pitx2:miR-200 Family Axis Regulates WNT and BMP Signaling During Tooth Morphogenesis and Renewal. The FASEB Journal. 2013 Apr 1; 27:193.1-193.1. Li LX, Cao CH, Jheon JA, Sun SZ, Wang WJ, Klein KO, Amendt AB. .
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    30. Essential Genes in the Development and Maintenance of the Temporomandibular Joint. The FASEB Journal. 2013 Apr 1; 27:319.5-319.5. Purcell PP, Hill HA, Jheon JA, Vivero VM, Duran DJ, Tabin TC, Klein KO, Warman WM. .
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    31. An Incisive Look at Stem Cells: The Mouse Incisor as an Emerging Model for Tooth Renewal. Stem Cells in Craniofacial Development and Regeneration. 2013 Mar 22; 315-327. Michon MF, Jheon JA, Seidel SK, Klein KO. .
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    32. Stem cell and biomaterials research in dental tissue engineering and regeneration. Dent Clin North Am. 2012 Jul; 56(3):495-520. Horst OV, Chavez MG, Jheon AH, Desai T, Klein OD. PMID: 22835534; PMCID: PMC3494412.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    33. From molecules to mastication: the development and evolution of teeth. Wiley Interdiscip Rev Dev Biol. 2013 Mar-Apr; 2(2):165-82. Jheon AH, Seidel K, Biehs B, Klein OD. PMID: 24009032; PMCID: PMC3632217.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    34. Regulation of Jaw Size During Development and Evolution. The FASEB Journal. 2012 Apr 1; 26:457.5-457.5. Ealba EE, Yu YJ, Jheon JA, Butcher BK, Schneider SR. .
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    35. Spry1 and spry2 are essential for development of the temporomandibular joint. J Dent Res. 2012 Apr; 91(4):387-93. Purcell P, Jheon A, Vivero MP, Rahimi H, Joo A, Klein OD. PMID: 22328578; PMCID: PMC3310757.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    36. Expression of microRNAs in the stem cell niche of the adult mouse incisor. PLoS One. 2011; 6(9):e24536. Jheon AH, Li CY, Wen T, Michon F, Klein OD. PMID: 21931743; PMCID: PMC3169592.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    37. Regulation of tooth number by fine-tuning levels of receptor-tyrosine kinase signaling. Development. 2011 Sep; 138(18):4063-73. Charles C, Hovorakova M, Ahn Y, Lyons DB, Marangoni P, Churava S, Biehs B, Jheon A, Lesot H, Balooch G, Krumlauf R, Viriot L, Peterkova R, Klein OD. PMID: 21862563; PMCID: PMC3160100.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    38. FGF signaling regulates the number of posterior taste papillae by controlling progenitor field size. PLoS Genet. 2011 Jun; 7(6):e1002098. Petersen CI, Jheon AH, Mostowfi P, Charles C, Ching S, Thirumangalathu S, Barlow LA, Klein OD. PMID: 21655085; PMCID: PMC3107195.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    39. Neural crest-mediated Runx2 expression regulates the development and evolution of the avian beak. The FASEB Journal. 2011 Apr 1; 25:302.2-302.2. Yu YJ, Jheon JA, Eames EB, Ealba EE, Butcher BK, Schneider SR. .
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    40. PERP regulates enamel formation via effects on cell-cell adhesion and gene expression. J Cell Sci. 2011 Mar 01; 124(Pt 5):745-54. Jheon AH, Mostowfi P, Snead ML, Ihrie RA, Sone E, Pramparo T, Attardi LD, Klein OD. PMID: 21285247; PMCID: PMC3039019.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    41. Mesenchymal regulation of vascular invasion and matrix remodeling during intramembranous ossification. Developmental Biology. 2009 Jul 1; 331(2):459. Ealba EE, Jheon JA, Butcher BK, Smith SF, Schneider SR. .
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    42. Mesenchymal regulation of mineralization and bone mineral density in the jaw skeleton. Developmental Biology. 2009 Jul 1; 331(2):459. Yu YJ, Jheon JA, Eames EB, Schneider SR. .
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    43. Characterisation of the constitutive over-expression of AJ18 in a novel rat stromal bone marrow cell line (D8-SBMC). Arch Oral Biol. 2009 Aug; 54(8):705-16. Jheon A, Bansal AK, Zhu B, Ganss B, Cheifetz S, Sodek J. PMID: 19473652.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    44. Mesenchymal regulation of mineralization and bone mineral density in the jaw skeleton. The FASEB Journal. 2009 Apr 1; 23:180.4-180.4. Yu YJ, Jheon JA, Eames EB, Schneider SR. .
      View in: Publisher Site   Mentions:
    45. Mesenchymal regulation of vascular invasion and matrix remodeling during intramembranous ossification. The FASEB Journal. 2009 Apr 1; 23:646.2-646.2. Butcher BK, Jheon JA, Smith SF, Schneider SR. .
      View in: Publisher Site   Mentions:
    46. The cells that fill the bill: neural crest and the evolution of craniofacial development. J Dent Res. 2009 Jan; 88(1):12-21. Jheon AH, Schneider RA. PMID: 19131312; PMCID: PMC3317957.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimals
    47. Bones and Cartilage: Developmental and Evolutionary Skeletal Biology. Acta Zoologica. 2008 Jul 1; 89(3):277-278. Jheon JA, Mitgutsch MC. .
      View in: Publisher Site   Mentions:
    48. Local and systemic mechanisms controlling osteogenesis. Developmental Biology. 2006 Jul 1; 295(1):400-401. Jheon JA, Eames EB, Schneider SR. .
      View in: Publisher Site   Mentions:
    49. Molecular cloning, structure, expression, and chromosomal localization of the human Osterix (SP7) gene. Gene. 2004 Oct 27; 341:101-10. Gao Y, Jheon A, Nourkeyhani H, Kobayashi H, Ganss B. PMID: 15474293.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    50. Zinc finger transcription factors in skeletal development. Crit Rev Oral Biol Med. 2004 Sep 01; 15(5):282-97. Ganss B, Jheon A. PMID: 15470266.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    51. The immune regulatory protein B7-H3 promotes osteoblast differentiation and bone mineralization. Proc Natl Acad Sci U S A. 2004 Aug 31; 101(35):12969-73. Suh WK, Wang SX, Jheon AH, Moreno L, Yoshinaga SK, Ganss B, Sodek J, Grynpas MD, Mak TW. PMID: 15317945; PMCID: PMC516502.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    52. Characterization of the 5'-flanking region of the rat AJ18 gene. Gene. 2003 May 22; 310:203-13. Jheon AH, Suzuki N, Nishiyama T, Cheifetz S, Sodek J, Ganss B. PMID: 12801648.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    53. Characterization of a novel KRAB/C2H2 zinc finger transcription factor involved in bone development. J Biol Chem. 2001 May 25; 276(21):18282-9. Jheon AH, Ganss B, Cheifetz S, Sodek J. PMID: 11278774.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
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