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Andrew Leavitt, MD

Title(s)Professor, Laboratory Medicine
SchoolSchool of Medicine
Phone415-353-2737
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPost-Doc Fellow/Scholar1991 Medicine (Cancer Research Institute)
    Harvard UniversityM.D.1984School of Medicine

    Collapse Research 
    Collapse Research Activities and Funding
    Structure Biology and Targeted Drug Design for AIDS
    NIH/NIGMS P01GM056531Sep 1, 1997 - Aug 31, 2007
    Role: Co-Investigator
    TRANSFUSION BIOLOGY AND MEDICINE
    NIH/NHLBI P50HL054476Feb 1, 1996 - Dec 31, 2006
    Role: Co-Investigator
    RETROVIRAL INTEGRATION
    NIH/NIAID R01AI036899Mar 1, 1994 - Feb 28, 1998
    Role: Principal Investigator
    DEVELOPMENT OF NEW APPROACHES TO INHIBIT GROWTH OF HIV
    NIH/NIAID U01AI027205Sep 1, 1988 - Nov 30, 1994
    Role: Co-Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Leaf RK, Ferreri C, Rangachari D, Mier J, Witteles W, Ansstas G, Anagnostou T, Zubiri L, Piotrowska Z, Oo TH, Iberri D, Yarchoan M, Salama AKS, Johnson DB, Leavitt AD, Rahma OE, Reynolds KL, Leaf DE. Clinical and laboratory features of autoimmune hemolytic anemia associated with immune checkpoint inhibitors. Am J Hematol. 2019 Feb 20. PMID: 30790338.
      View in: PubMed
    2. Bu W, Liu Z, Jiang W, Nagi C, Huang S, Edwards DP, Jo E, Mo Q, Creighton CJ, Hilsenbeck SG, Leavitt AD, Lewis MT, Wong STC, Li Y. Mammary Precancerous Stem and Non-Stem Cells Evolve into Cancers of Distinct Subtypes. Cancer Res. 2019 Jan 01; 79(1):61-71. PMID: 30401712.
      View in: PubMed
    3. Vu K, Leavitt AD. Posttransfusion purpura with antibodies against human platelet antigen-4a following checkpoint inhibitor therapy: a case report and review of the literature. Transfusion. 2018 Oct; 58(10):2265-2269. PMID: 30222869.
      View in: PubMed
    4. Leavitt AD. A Small Step Closer But Not Yet There: Oral Anti-Xa Agents and the Treatment of Cancer-Associated Venous Thromboembolism. J Natl Compr Canc Netw. 2018 May; 16(5):572-574. PMID: 29752330.
      View in: PubMed
    5. Lee EJ, Dykas DJ, Leavitt AD, Camire RM, Ebberink E, García de Frutos P, Gnanasambandan K, Gu SX, Huntington JA, Lentz SR, Mertens K, Parish CR, Rezaie AR, Sayeski PP, Cromwell C, Bar N, Halene S, Neparidze N, Parker TL, Burns AJ, Dumont A, Yao X, Chaar CIO, Connors JM, Bale AE, Lee AI. Whole-exome sequencing in evaluation of patients with venous thromboembolism. Blood Adv. 2017 Jul 11; 1(16):1224-1237. PMID: 29296762.
      View in: PubMed
    6. Lefrançais E, Ortiz-Muñoz G, Caudrillier A, Mallavia B, Liu F, Sayah DM, Thornton EE, Headley MB, David T, Coughlin SR, Krummel MF, Leavitt AD, Passegué E, Looney MR. The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors. Nature. 2017 04 06; 544(7648):105-109. PMID: 28329764.
      View in: PubMed
    7. Sakurai K, Zhao S, Takatoh J, Rodriguez E, Lu J, Leavitt AD, Fu M, Han BX, Wang F. Capturing and Manipulating Activated Neuronal Ensembles with CANE Delineates a Hypothalamic Social-Fear Circuit. Neuron. 2016 Nov 23; 92(4):739-753. PMID: 27974160.
      View in: PubMed
    8. Buckner TW, Leavitt AD, Ragni M, Kempton CL, Eyster ME, Cuker A, Lentz SR, Ducore J, Leissinger C, Wang M, Key NS. Prospective, multicenter study of postoperative deep-vein thrombosis in patients with haemophilia undergoing major orthopaedic surgery. Thromb Haemost. 2016 07 04; 116(1):42-9. PMID: 27009484.
      View in: PubMed
    9. Pietras EM, Reynaud D, Kang YA, Carlin D, Calero-Nieto FJ, Leavitt AD, Stuart JM, Göttgens B, Passegué E. Functionally Distinct Subsets of Lineage-Biased Multipotent Progenitors Control Blood Production in Normal and Regenerative Conditions. Cell Stem Cell. 2015 Jul 02; 17(1):35-46. PMID: 26095048; PMCID: PMC4542150.
    10. Low E, Tessler R, Hauer KE, Leavitt AD, Miller B, Maa J. The Surgical Clerkship and Medical Student Performance in a Standardized Patient Case of Acute Cholecystitis. J Surg Educ. 2015 Sep-Oct; 72(5):1045-51. PMID: 26089162.
      View in: PubMed
    11. Roubinian NH, Leavitt AD. Shedding a little light on posttransfusion purpura. Transfusion. 2015 Feb; 55(2):232-4. PMID: 25683186.
      View in: PubMed
    12. Wilson JG, Liu KD, Zhuo H, Caballero L, McMillan M, Fang X, Cosgrove K, Vojnik R, Calfee CS, Lee JW, Rogers AJ, Levitt J, Wiener-Kronish J, Bajwa EK, Leavitt A, McKenna D, Thompson BT, Matthay MA. Mesenchymal stem (stromal) cells for treatment of ARDS: a phase 1 clinical trial. Lancet Respir Med. 2015 Jan; 3(1):24-32. PMID: 25529339; PMCID: PMC4297579.
    13. Liu KD, Wilson JG, Zhuo H, Caballero L, McMillan ML, Fang X, Cosgrove K, Calfee CS, Lee JW, Kangelaris KN, Gotts JE, Rogers AJ, Levitt JE, Wiener-Kronish JP, Delucchi KL, Leavitt AD, McKenna DH, Thompson BT, Matthay MA. Design and implementation of the START (STem cells for ARDS Treatment) trial, a phase 1/2 trial of human mesenchymal stem/stromal cells for the treatment of moderate-severe acute respiratory distress syndrome. Ann Intensive Care. 2014; 4:22. PMID: 25593740; PMCID: PMC4273700.
    14. Kamata T, Dankort D, Kang J, Giblett S, Pritchard CA, McMahon M, Leavitt AD. Hematopoietic expression of oncogenic BRAF promotes aberrant growth of monocyte-lineage cells resistant to PLX4720. Mol Cancer Res. 2013 Dec; 11(12):1530-41. PMID: 24152792; PMCID: PMC3869667.
    15. Jacquot C, Moayeri M, Kim B, Shugarts S, Lynch KL, Leavitt AD. Prolonged ceftriaxone-induced immune thrombocytopenia due to impaired drug clearance: a case report. Transfusion. 2013 Nov; 53(11):2715-21. PMID: 23451879.
      View in: PubMed
    16. Choi YS, Patena W, Leavitt AD, McManus MT. Widespread RNA 3'-end oligouridylation in mammals. RNA. 2012 Mar; 18(3):394-401. PMID: 22291204; PMCID: PMC3285928.
    17. Leavitt AD, Hamlett I. Homologous recombination in human embryonic stem cells: a tool for advancing cell therapy and understanding and treating human disease. Clin Transl Sci. 2011 Aug; 4(4):298-305. PMID: 21884519.
      View in: PubMed
    18. Leavitt AD. A vote for scientists as politicians. Science. 2011 Feb 25; 331(6020):1010. PMID: 21350149.
      View in: PubMed
    19. Leavitt AD. Are there more tricks in the bag for treating thrombocytopenia? J Clin Invest. 2010 Nov; 120(11):3807-10. PMID: 20972327; PMCID: PMC2965007.
    20. King FW, Ritner C, Liszewski W, Kwan HC, Pedersen A, Leavitt AD, Bernstein HS. Subpopulations of human embryonic stem cells with distinct tissue-specific fates can be selected from pluripotent cultures. Stem Cells Dev. 2009 Dec; 18(10):1441-50. PMID: 19254177; PMCID: PMC2939715.
    21. Alian A, Griner SL, Chiang V, Tsiang M, Jones G, Birkus G, Geleziunas R, Leavitt AD, Stroud RM. Catalytically-active complex of HIV-1 integrase with a viral DNA substrate binds anti-integrase drugs. Proc Natl Acad Sci U S A. 2009 May 19; 106(20):8192-7. PMID: 19416821; PMCID: PMC2688900.
    22. Nicholas CR, Gaur M, Wang S, Pera RA, Leavitt AD. A method for single-cell sorting and expansion of genetically modified human embryonic stem cells. Stem Cells Dev. 2007 Feb; 16(1):109-17. PMID: 17348809.
      View in: PubMed
    23. Kamata T, Kang J, Lee TH, Wojnowski L, Pritchard CA, Leavitt AD. A critical function for B-Raf at multiple stages of myelopoiesis. Blood. 2005 Aug 01; 106(3):833-40. PMID: 15784729; PMCID: PMC1895151.
    24. Kerrigan SW, Gaur M, Murphy RP, Shattil SJ, Leavitt AD. Caspase-12: a developmental link between G-protein-coupled receptors and integrin alphaIIbbeta3 activation. Blood. 2004 Sep 01; 104(5):1327-34. PMID: 15059849.
      View in: PubMed
    25. Gaur M, Murphy GJ, Frampton J, Leavitt AD. Using retroviruses to express genes in primary megakaryocyte lineage cells. Methods Mol Biol. 2004; 273:381-96. PMID: 15308813.
      View in: PubMed
    26. Kamata T, Pritchard CA, Leavitt AD. Raf-1 is not required for megakaryocytopoiesis or TPO-induced ERK phosphorylation. Blood. 2004 Apr 01; 103(7):2568-70. PMID: 14576068.
      View in: PubMed
    27. Murphy GJ, Göttgens B, Vegiopoulos A, Sanchez MJ, Leavitt AD, Watson SP, Green AR, Frampton J. Manipulation of mouse hematopoietic progenitors by specific retroviral infection. J Biol Chem. 2003 Oct 31; 278(44):43556-63. PMID: 12928443.
      View in: PubMed
    28. Eto K, Murphy R, Kerrigan SW, Bertoni A, Stuhlmann H, Nakano T, Leavitt AD, Shattil SJ. Megakaryocytes derived from embryonic stem cells implicate CalDAG-GEFI in integrin signaling. Proc Natl Acad Sci U S A. 2002 Oct 01; 99(20):12819-24. PMID: 12239348; PMCID: PMC130543.