Anoop Sheshadri, MD

Title(s)Assistant Professor, Medicine
SchoolSchool of Medicine
Address4150 Clement Street
San Francisco CA 94121
Phone415-221-2810 ext. 23598
ORCID ORCID Icon0000-0002-1139-0169 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of Texas Southwestern Medical Center, Dallas, TXMD06/2011
    University of Texas Southwestern Medical Center , Dallas, TXMDInternal Medicine
    University of California, San Francisco, San FranciscoMS03/2018Masters in Clinical Research
    University of California, San Francisco01/2021Diversity, Equity, and Inclusion Champion Training
    Collapse Awards and Honors
    University of Texas Southwestern Medical Center2014John S. Miller Award for Outstanding Senior Resident in Internal Medicine
    American Kidney Foundation2016Clinical Scientist in Nephrology Fellow
    University of California, San Francisco20172017 Andy M. Choi Memorial Scholarship
    University of California, San Francisco2020CLIN-STAR 2020 Research "Shark Tank" Presentation Winner
    2021Featured interview on CLIN-STAR Journey Stories

    Collapse Overview 
    Collapse Overview
    I am a nephrologist with a focus on improving outcomes and care for older and elderly patients. My career goal is to be a pioneer in research at the intersection of aging, nephrology, and transplantation. To that end my current focus has been on prehabilitation in older patients awaiting kidney transplantation.

    Collapse Research 
    Collapse Research Activities and Funding
    Structured Program of exercise for Recipients of Kidney Transplant
    UCSF KL2 TR001870-06Jul 1, 2021 - Jun 30, 2024
    Role: PI
    Description: The overall objective of this proposal is to adapt a previously developed 8- week, home- based, structured exercise program among older dialysis patients awaiting living donor kidney transplantation, with a focus on caregiver involvement. We will recruit 10-15 paired patient-caregiver dyads to refine the intervention using a process of iterative feedback, and then conduct focus group interviews to establish a consensus. After iteratively incorporating changes, we will trial the exercise program as compared to usual care. We will then pilot the refined intervention in a total of 72 patient-caregiver dyads, 48 of whom will undergo the proposed intervention (24 with caregiver participation, 24 without). We will assess feasibility and acceptability of the intervention to patients and caregivers during the adaptation phase. Our primary outcomes for the pilot will be change in physical performance and activity from baseline to after the intervention, along with measurements of exploratory quality of life outcomes. In addition, we will measure these same outcomes at 3- months post transplantation to evaluate for a durable effect of the intervention. An additional post-transplantation outcome of interest will be number of days hospitalized within 3 months of transplantation.
    Identifying Goals and Barriers to Exercise for Prehabilitation in Older Adults awaiting Kidney Transplantation and their Caregivers
    NIH R03AG067981Sep 1, 2020 - May 31, 2022
    Role: Principal Investigator
    Identifying Goals for and Barriers to Prehabilitation in Older Adults with End-Stage Renal Disease Awaiting Kidney Transplantation and Community Engagement in ESKD (suppl.)
    UCSF UCSF RAP Award Fall 2019 CycleFeb 1, 2020 - Dec 31, 2021
    Role: PI
    Description: The goal of this project is to understand at a detailed level the preferences and abilities of older patients awaiting KT and their caregivers regarding exercise interventions prior to KT. Such an intervention cannot succeed without first obtaining patient and caregiver input, ideally delivered directly through their own voices. Our project seeks to understand the impact of aging and ESRD in this critical transition period not only through the lens of the patient potentially undergoing KT, but also the family members, close friends, and other members of the community who support them during this time. We plan to not only interview members of the ESRD community awaiting KT directly and also create a collaborative network for participation in future semi-structured focus groups to discuss the design of a future intervention that will be piloted within this same community. Such an intervention, once optimized, would be the cornerstone of a comprehensive prehabilitation program for patients awaiting KT. We envision that this program would include as stakeholders and decision-makers not only physicians or clinical staff providing kidney transplant and associated care, but also the patients and caregivers whose lives would be most affected by prehabilitation prior to KT.
    Pedometers and Exercise in Dialysis
    NIH F32DK111154Mar 8, 2017 - Mar 7, 2019
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Barriers and Facilitators to Exercise in Older Adults Awaiting Kidney Transplantation and Their Care Partners. Kidney Med. 2024 Mar; 6(3):100779. Sheshadri A, Elia JR, Garcia G, Abrams G, Adey DB, Lai JC, Sudore RL. PMID: 38419789; PMCID: PMC10900112.
      View in: PubMed   Mentions:
    2. Structured Moderate Exercise and Biomarkers of Kidney Health in Sedentary Older Adults: The Lifestyle Interventions and Independence for Elders Randomized Clinical Trial. Kidney Med. 2023 Nov; 5(11):100721. Sheshadri A, Lai M, Hsu FC, Bauer SR, Chen SH, Tse W, Jotwani V, Tranah GJ, Lai JC, Hallan S, Fielding RA, Liu C, Ix JH, Coca SG, Shlipak MG. PMID: 37915963; PMCID: PMC10616412.
      View in: PubMed   Mentions: 1  
    3. Physical Resilience in Older Patients Incident to Hemodialysis: Can Following Trajectories Improve Our Ability to Intervene on Functional Decline? Kidney Int Rep. 2022 Sep; 7(9):1927-1929. Sheshadri A, Elia JR. PMID: 36090497; PMCID: PMC9459025.
      View in: PubMed   Mentions:
    4. Effect of Structured, Moderate Exercise on Kidney Function Decline in Sedentary Older Adults: An Ancillary Analysis of the LIFE Study Randomized Clinical Trial. JAMA Intern Med. 2022 06 01; 182(6):650-659. Shlipak MG, Sheshadri A, Hsu FC, Chen SH, Jotwani V, Tranah G, Fielding RA, Liu CK, Ix J, Coca SG, LIFE Investigators. PMID: 35499834; PMCID: PMC9062767.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    5. Longitudinal Assessment of Body Composition and Its Association With Survival Among Participants of the ACTIVE/ADIPOSE Study. J Ren Nutr. 2022 07; 32(4):396-404. Delgado C, Chiang JM, Kittiskulnam P, Sheshadri A, Grimes B, Segal M, Kaysen GA, Johansen KL. PMID: 34930665.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    6. Association of Cognitive Function Screening Results with Adherence and Performance in a Pedometer-Based Intervention. Am J Nephrol. 2021; 52(5):420-428. Sheshadri A, Kittiskulnam P, Delgado C, Sudore RL, Lai JC, Johansen KL. PMID: 33979802; PMCID: PMC8263507.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    7. Association of motivations and barriers with participation and performance in a pedometer-based intervention. Nephrol Dial Transplant. 2020 08 01; 35(8):1405-1411. Sheshadri A, Kittiskulnam P, Delgado C, Sudore R, Lai JC, Johansen KL. PMID: 32437568; PMCID: PMC8524721.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    8. Association of Karnofsky Performance Status with waitlist mortality among older and younger adults awaiting kidney transplantation. Clin Transplant. 2020 06; 34(6):e13848. Sheshadri A, Cullaro G, Johansen KL, Lai JC. PMID: 32112458; PMCID: PMC10123007.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    9. Effect of a pedometer-based walking intervention on body composition in patients with ESRD: a randomized controlled trial. BMC Nephrol. 2020 03 16; 21(1):100. Sheshadri A, Kittiskulnam P, Lai JC, Johansen KL. PMID: 32178648; PMCID: PMC7074998.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    10. A Walking Intervention to Increase Weekly Steps in Dialysis Patients: A Pilot Randomized Controlled Trial. Am J Kidney Dis. 2020 04; 75(4):488-496. Sheshadri A, Kittiskulnam P, Lazar AA, Johansen KL. PMID: 31679747; PMCID: PMC7089809.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    11. Validation of a New Physical Activity Instrument Against Pedometers Among Dialysis Patients. J Ren Nutr. 2019 11; 29(6):498-503. Kittiskulnam P, Sheshadri A, Johansen KL. PMID: 31078404; PMCID: PMC6825523.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. Higher Physical Activity Is Associated With Less Fatigue and Insomnia Among Patients on Hemodialysis. Kidney Int Rep. 2019 Feb; 4(2):285-292. Sheshadri A, Kittiskulnam P, Johansen KL. PMID: 30775625; PMCID: PMC6365400.
      View in: PubMed   Mentions: 16  
    13. Prehabilitation for the Frail Patient Approaching ESRD. Semin Nephrol. 2017 03; 37(2):159-172. Sheshadri A, Johansen KL. PMID: 28410650; PMCID: PMC5393359.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    14. Consequences of CKD on Functioning. Semin Nephrol. 2016 07; 36(4):305-18. Kittiskulnam P, Sheshadri A, Johansen KL. PMID: 27475661; PMCID: PMC4967875.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
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