|Structured Program of exercise for Recipients of Kidney Transplant
UCSF KL2 TR001870-06Jul 1, 2021 - Jun 30, 2024
Description: The overall objective of this proposal is to adapt a previously developed 8- week, home- based, structured exercise program among older dialysis patients awaiting living donor kidney transplantation, with a focus on caregiver involvement. We will recruit 10-15 paired patient-caregiver dyads to refine the intervention using a process of iterative feedback, and then conduct focus group interviews to establish a consensus. After iteratively incorporating changes, we will trial the exercise program as compared to usual care. We will then pilot the refined intervention in a total of 72 patient-caregiver dyads, 48 of whom will undergo the proposed intervention (24 with caregiver participation, 24 without). We will assess feasibility and acceptability of the intervention to patients and caregivers during the adaptation phase. Our primary outcomes for the pilot will be change in physical performance and activity from baseline to after the intervention, along with measurements of exploratory quality of life outcomes. In addition, we will measure these same outcomes at 3- months post transplantation to evaluate for a durable effect of the intervention. An additional post-transplantation outcome of interest will be number of days hospitalized within 3 months of transplantation.
|Identifying Goals and Barriers to Exercise for Prehabilitation in Older Adults awaiting Kidney Transplantation and their Caregivers
NIH R03AG067981Sep 1, 2020 - May 31, 2022
Role: Principal Investigator
|Identifying Goals for and Barriers to Prehabilitation in Older Adults with End-Stage Renal Disease Awaiting Kidney Transplantation and Community Engagement in ESKD (suppl.)
UCSF UCSF RAP Award Fall 2019 CycleFeb 1, 2020 - Dec 31, 2021
Description: The goal of this project is to understand at a detailed level the preferences and abilities of older patients awaiting KT and their caregivers regarding exercise interventions prior to KT. Such an intervention cannot succeed without first obtaining patient and caregiver input, ideally delivered directly through their own voices. Our project seeks to understand the impact of aging and ESRD in this critical transition period not only through the lens of the patient potentially undergoing KT, but also the family members, close friends, and other members of the community who support them during this time. We plan to not only interview members of the ESRD community awaiting KT directly and also create a collaborative network for participation in future semi-structured focus groups to discuss the design of a future intervention that will be piloted within this same community. Such an intervention, once optimized, would be the cornerstone of a comprehensive prehabilitation program for patients awaiting KT. We envision that this program would include as stakeholders and decision-makers not only physicians or clinical staff providing kidney transplant and associated care, but also the patients and caregivers whose lives would be most affected by prehabilitation prior to KT.
|Pedometers and Exercise in Dialysis
NIH F32DK111154Mar 8, 2017 - Mar 7, 2019
Role: Principal Investigator