Anthony Baker, PhD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address4150 Clement St, #111C
San Francisco CA 94121
Phone415-221-4810 ext. 4790
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    Collapse Biography 
    Collapse Education and Training
    University of York, York, UKBA1979Biology
    University of Bristol, Bristol, UKPhD1984Physiology
    University of California, San Francisco, San Francisco, CA1986Biophysics

    Collapse Overview 
    Collapse Overview
    Anthony J. Baker, Ph.D. has a longstanding interest in the cellular and molecular mechanisms that regulate cardiac muscle contraction in health and disease. We study cardiac function in experimental preparations that span a range of spatial scales and complexity, including single cells, isolated cardiac muscle and intact hearts in-vivo. A major goal is to investigate new therapies to treat heart failure. We are studying heart failure involving the right ventricle (RV) of the heart. Currently, there is no effective pharmacologic treatment for RV failure. Our recent studies show that a class of adrenergic drugs can reverse RV failure. We are investigating how these drugs work, and if they might be used to treat RV failure.

    Collapse Research 
    Collapse Research Activities and Funding
    Right Heart Function in Health and Chronic Disease
    Department of Veterans Affairs, BIOMEDICAL LABORATORY RESEARCH & DEVELOPMENT Sep 30, 2023 - Oct 1, 2027
    Multiscale mechanobiology of right ventricular failure
    NIH R01HL154624Jul 1, 2020 - Jun 30, 2025
    Role: Co-Principal Investigator
    LAMb request for a Berchtold LED F 628 Surgical Light System
    NIH IS1BX004003Jan 1, 2017 - Sep 30, 2017
    Role: Principal Investigator
    Request for Purchase of High-Performance MRI System for in-vivo Rodent Imaging
    NIH IS1BX003101Apr 1, 2015 - Sep 30, 2015
    Role: Principal Investigator
    Right Heart Function in Health and Chronic Disease
    NIH I01BX000740Apr 1, 2010 - Sep 30, 2023
    Role: PI
    UCSF Living Heart Resource
    NIH RC1HL099789Sep 30, 2009 - Aug 31, 2011
    Role: Co-Principal Investigator
    Mechanisms of Cardioprotection in Ischemia and Failure
    NIH P01HL068738Aug 1, 2002 - Jul 31, 2008
    Role: Co-Principal Investigator
    MECHANISMS OF SLOWED MYOCARDIAL RELAXATION
    NIH R29HL056257Aug 15, 1997 - Dec 31, 2002
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Academic Senate

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Increased length-dependent activation of human engineered heart tissue after chronic α1A-adrenergic agonist treatment: testing a novel heart failure therapy. Am J Physiol Heart Circ Physiol. 2023 03 01; 324(3):H293-H304. Rupert C, López JE, Cortez-Toledo E, De la Cruz Cabrera O, Chesler NC, Simpson PC, Campbell SG, Baker AJ. PMID: 36637971; PMCID: PMC9886349.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Reduced cardiac muscle power with low ATP simulating heart failure. Biophys J. 2022 09 06; 121(17):3213-3223. Beard DA, Marzban B, Li OY, Campbell KS, Janssen PML, Chesler NC, Baker AJ. PMID: 35918899; PMCID: PMC9463691.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    3. Emergence of Mechano-Sensitive Contraction Autoregulation in Cardiomyocytes. Life (Basel). 2021 May 29; 11(6). Izu L, Shimkunas R, Jian Z, Hegyi B, Kazemi-Lari M, Baker A, Shaw J, Banyasz T, Chen-Izu Y. PMID: 34072584; PMCID: PMC8227646.
      View in: PubMed   Mentions: 3  
    4. Mechanical Load Regulates Excitation-Ca2+ Signaling-Contraction in Cardiomyocyte. Circ Res. 2021 03 19; 128(6):772-774. Shimkunas R, Hegyi B, Jian Z, Shaw JA, Kazemi-Lari MA, Mitra D, Leach JK, Li X, Jaradeh M, Balardi N, Chen YJ, Escobar AL, Baker AJ, Bossuyt J, Banyasz T, Chiamvimonvat N, Lam KS, Bers DM, Izu LT, Chen-Izu Y. PMID: 33601939; PMCID: PMC7979518.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    5. Myocardial injection of a thermoresponsive hydrogel with reactive oxygen species scavenger properties improves border zone contractility. J Biomed Mater Res A. 2020 08 01; 108(8):1736-1746. Spaulding KA, Zhu Y, Takaba K, Ramasubramanian A, Badathala A, Haraldsson H, Collins A, Aguayo E, Shah C, Wallace AW, Ziats NP, Lovett DH, Baker AJ, Healy KE, Ratcliffe MB. PMID: 32270584; PMCID: PMC8174154.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    6. Coupling to Gq Signaling Is Required for Cardioprotection by an Alpha-1A-Adrenergic Receptor Agonist. Circ Res. 2019 09 13; 125(7):699-706. Myagmar BE, Ismaili T, Swigart PM, Raghunathan A, Baker AJ, Sahdeo S, Blevitt JM, Milla ME, Simpson PC. PMID: 31426700; PMCID: PMC6742539.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    7. Monitoring the Health Status of Mice with Bleomycin-induced Lung Injury by Using Body Condition Scoring. Comp Med. 2019 04 01; 69(2):95-102. Cowley PM, Roberts CR, Baker AJ. PMID: 30808435; PMCID: PMC6464078.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    8. Reversal of right ventricular failure by chronic α1A-subtype adrenergic agonist therapy. Am J Physiol Heart Circ Physiol. 2019 01 01; 316(1):H224-H232. Cowley PM, Wang G, Swigart PM, Raghunathan A, Reddy N, Dulam P, Lovett DH, Simpson PC, Baker AJ. PMID: 30412439; PMCID: PMC6859419.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    9. Human Myocardium Has a Robust α1A-Subtype Adrenergic Receptor Inotropic Response. J Cardiovasc Pharmacol. 2018 09; 72(3):136-142. Janssen PML, Canan BD, Kilic A, Whitson BA, Baker AJ. PMID: 29923888; PMCID: PMC6126952.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    10. Multiscale Computational Analysis of Right Ventricular Mechanoenergetics. J Biomech Eng. 2018 08 01; 140(8). Pewowaruk RJ, Philip JL, Tewari SG, Chen CS, Nyaeme MS, Wang Z, Tabima DM, Baker AJ, Beard DA, Chesler NC. PMID: 30003251; PMCID: PMC6056199.
      View in: PubMed   Mentions: 5     Fields:    
    11. Impaired Myofilament Contraction Drives Right Ventricular Failure Secondary to Pressure Overload: Model Simulations, Experimental Validation, and Treatment Predictions. Front Physiol. 2018; 9:731. Philip JL, Pewowaruk RJ, Chen CS, Tabima DM, Beard DA, Baker AJ, Chesler NC. PMID: 29997518; PMCID: PMC6030352.
      View in: PubMed   Mentions: 5  
    12. Short term doxycycline treatment induces sustained improvement in myocardial infarction border zone contractility. PLoS One. 2018; 13(2):e0192720. Spaulding K, Takaba K, Collins A, Faraji F, Wang G, Aguayo E, Ge L, Saloner D, Wallace AW, Baker AJ, Lovett DH, Ratcliffe MB. PMID: 29432443; PMCID: PMC5809072.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    13. α1A-Subtype adrenergic agonist therapy for the failing right ventricle. Am J Physiol Heart Circ Physiol. 2017 Dec 01; 313(6):H1109-H1118. Cowley PM, Wang G, Joshi S, Swigart PM, Lovett DH, Simpson PC, Baker AJ. PMID: 28822963; PMCID: PMC5814653.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    14. Hyperpolarized 13 C magnetic resonance evaluation of renal ischemia reperfusion injury in a murine model. NMR Biomed. 2017 Oct; 30(10). Baligand C, Qin H, True-Yasaki A, Gordon JW, von Morze C, Santos JD, Wilson DM, Raffai R, Cowley PM, Baker AJ, Kurhanewicz J, Lovett DH, Wang ZJ. PMID: 28708304; PMCID: PMC5618802.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    15. Response by Simpson et al to Letter Regarding Article, "Adrenergic Receptors in Individual Ventricular Myocytes: the Beta-1 and Alpha-1B Are in All Cells, the Alpha-1A Is in a Subpopulation, and the Beta-2 and Beta-3 Are Mostly Absent". Circ Res. 2017 06 09; 120(12):e56-e57. Simpson PC, Myagmar BE, Swigart PM, Melov S, Baker AJ. PMID: 28596177; PMCID: PMC5501172.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    16. An intracellular matrix metalloproteinase-2 isoform induces tubular regulated necrosis: implications for acute kidney injury. Am J Physiol Renal Physiol. 2017 06 01; 312(6):F1166-F1183. Ceron CS, Baligand C, Joshi S, Wanga S, Cowley PM, Walker JP, Song SH, Mahimkar R, Baker AJ, Raffai RL, Wang ZJ, Lovett DH. PMID: 28331061; PMCID: PMC5495883.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    17. Adrenergic Receptors in Individual Ventricular Myocytes: The Beta-1 and Alpha-1B Are in All Cells, the Alpha-1A Is in a Subpopulation, and the Beta-2 and Beta-3 Are Mostly Absent. Circ Res. 2017 Mar 31; 120(7):1103-1115. Myagmar BE, Flynn JM, Cowley PM, Swigart PM, Montgomery MD, Thai K, Nair D, Gupta R, Deng DX, Hosoda C, Melov S, Baker AJ, Simpson PC. PMID: 28219977; PMCID: PMC5376223.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    18. The Alpha-1A Adrenergic Receptor in the Rabbit Heart. PLoS One. 2016; 11(6):e0155238. Thomas RC, Cowley PM, Singh A, Myagmar BE, Swigart PM, Baker AJ, Simpson PC. PMID: 27258143; PMCID: PMC4892533.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    19. A Myocardial Slice Culture Model Reveals Alpha-1A-Adrenergic Receptor Signaling in the Human Heart. JACC Basic Transl Sci. 2016 04; 1(3):155-167. Thomas RC, Singh A, Cowley P, Myagmar BE, Montgomery MD, Swigart PM, De Marco T, Baker AJ, Simpson PC. PMID: 27453955; PMCID: PMC4955869.
      View in: PubMed   Mentions: 20  
    20. The α1A-adrenergic receptor subtype mediates increased contraction of failing right ventricular myocardium. Am J Physiol Heart Circ Physiol. 2015 Sep; 309(5):H888-96. Cowley PM, Wang G, Chang AN, Makwana O, Swigart PM, Lovett DH, Stull JT, Simpson PC, Baker AJ. PMID: 26116709; PMCID: PMC4591405.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    21. Constitutive phosphorylation of cardiac myosin regulatory light chain in vivo. J Biol Chem. 2015 Apr 24; 290(17):10703-16. Chang AN, Battiprolu PK, Cowley PM, Chen G, Gerard RD, Pinto JR, Hill JA, Baker AJ, Kamm KE, Stull JT. PMID: 25733667; PMCID: PMC4409237.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    22. A N-terminal truncated intracellular isoform of matrix metalloproteinase-2 impairs contractility of mouse myocardium. Front Physiol. 2014; 5:363. Lovett DH, Chu C, Wang G, Ratcliffe MB, Baker AJ. PMID: 25309453; PMCID: PMC4174733.
      View in: PubMed   Mentions: 11  
    23. Myofilament dysfunction contributes to impaired myocardial contraction in the infarct border zone. Am J Physiol Heart Circ Physiol. 2014 Oct 15; 307(8):H1150-8. Shimkunas R, Makwana O, Spaulding K, Bazargan M, Khazalpour M, Takaba K, Soleimani M, Myagmar BE, Lovett DH, Simpson PC, Ratcliffe MB, Baker AJ. PMID: 25128171; PMCID: PMC4200338.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    24. Adrenergic signaling in heart failure: a balance of toxic and protective effects. Pflugers Arch. 2014 Jun; 466(6):1139-50. Baker AJ. PMID: 24623099.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    25. Cardiac alpha1-adrenergic receptors: novel aspects of expression, signaling mechanisms, physiologic function, and clinical importance. Pharmacol Rev. 2014; 66(1):308-33. O'Connell TD, Jensen BC, Baker AJ, Simpson PC. PMID: 24368739; PMCID: PMC3880467.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    26. N-terminal truncated intracellular matrix metalloproteinase-2 induces cardiomyocyte hypertrophy, inflammation and systolic heart failure. PLoS One. 2013; 8(7):e68154. Lovett DH, Mahimkar R, Raffai RL, Cape L, Zhu BQ, Jin ZQ, Baker AJ, Karliner JS. PMID: 23874529; PMCID: PMC3712965.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    27. Left ventricular myocardial contractility is depressed in the borderzone after posterolateral myocardial infarction. Ann Thorac Surg. 2013 May; 95(5):1619-25. Shimkunas R, Zhang Z, Wenk JF, Soleimani M, Khazalpour M, Acevedo-Bolton G, Wang G, Saloner D, Mishra R, Wallace AW, Ge L, Baker AJ, Guccione JM, Ratcliffe MB. PMID: 23523189; PMCID: PMC3640420.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    28. Intraventricular and interventricular cellular heterogeneity of inotropic responses to α(1)-adrenergic stimulation. Am J Physiol Heart Circ Physiol. 2013 Apr 01; 304(7):H946-53. Chu C, Thai K, Park KW, Wang P, Makwana O, Lovett DH, Simpson PC, Baker AJ. PMID: 23355341; PMCID: PMC3625891.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    29. The benefit of enhanced contractility in the infarct borderzone: a virtual experiment. Front Physiol. 2012; 3:86. Zhang Z, Sun K, Saloner DA, Wallace AW, Ge L, Baker AJ, Guccione JM, Ratcliffe MB. PMID: 22509168; PMCID: PMC3321638.
      View in: PubMed   Mentions: 7  
    30. Refueling the heart: Using 2-deoxy-ATP to enhance cardiac contractility. J Mol Cell Cardiol. 2011 Dec; 51(6):883-4. Baker AJ. PMID: 22001677.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    31. Myo-mechanical analysis of isolated skeletal muscle. J Vis Exp. 2011 Feb 22; (48). Oishi PE, Cholsiripunlert S, Gong W, Baker AJ, Bernstein HS. PMID: 21403622; PMCID: PMC3164512.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    32. Distinctive ERK and p38 signaling in remote and infarcted myocardium during post-MI remodeling in the mouse. J Cell Biochem. 2010 Apr 15; 109(6):1185-91. Yeh CC, Li H, Malhotra D, Turcato S, Nicholas S, Tu R, Zhu BQ, Cha J, Swigart PM, Myagmar BE, Baker AJ, Simpson PC, Mann MJ. PMID: 20186881; PMCID: PMC3397305.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    33. Heart failure switches the RV alpha1-adrenergic inotropic response from negative to positive. Am J Physiol Heart Circ Physiol. 2010 Mar; 298(3):H913-20. Wang GY, Yeh CC, Jensen BC, Mann MJ, Simpson PC, Baker AJ. PMID: 20035030; PMCID: PMC2838546.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    34. A computationally efficient formal optimization of regional myocardial contractility in a sheep with left ventricular aneurysm. J Biomech Eng. 2009 Nov; 131(11):111001. Sun K, Stander N, Jhun CS, Zhang Z, Suzuki T, Wang GY, Saeed M, Wallace AW, Tseng EE, Baker AJ, Saloner D, Einstein DR, Ratcliffe MB, Guccione JM. PMID: 20016753; PMCID: PMC2793686.
      View in: PubMed   Mentions: 48     Fields:    Translation:Animals
    35. Expression of a Gi-coupled receptor in the heart causes impaired Ca2+ handling, myofilament injury, and dilated cardiomyopathy. Am J Physiol Heart Circ Physiol. 2008 Jan; 294(1):H205-12. McCloskey DT, Turcato S, Wang GY, Turnbull L, Zhu BQ, Bambino T, Nguyen AP, Lovett DH, Nissenson RA, Karliner JS, Baker AJ. PMID: 17965283; PMCID: PMC3372085.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    36. Transgenic MMP-2 expression induces latent cardiac mitochondrial dysfunction. Biochem Biophys Res Commun. 2007 Jun 22; 358(1):189-95. Zhou HZ, Ma X, Gray MO, Zhu BQ, Nguyen AP, Baker AJ, Simonis U, Cecchini G, Lovett DH, Karliner JS. PMID: 17475219; PMCID: PMC3423089.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    37. Contrasting inotropic responses to alpha1-adrenergic receptor stimulation in left versus right ventricular myocardium. Am J Physiol Heart Circ Physiol. 2006 Oct; 291(4):H2013-7. Wang GY, McCloskey DT, Turcato S, Swigart PM, Simpson PC, Baker AJ. PMID: 16731650.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    38. Alpha1-adrenergic receptors prevent a maladaptive cardiac response to pressure overload. J Clin Invest. 2006 Apr; 116(4):1005-15. O'Connell TD, Swigart PM, Rodrigo MC, Ishizaka S, Joho S, Turnbull L, Tecott LH, Baker AJ, Foster E, Grossman W, Simpson PC. PMID: 16585965; PMCID: PMC1421341.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    39. Ischemic preconditioning depends on age and gender. Basic Res Cardiol. 2006 May; 101(3):235-43. Turcato S, Turnbull L, Wang GY, Honbo N, Simpson PC, Karliner JS, Baker AJ. PMID: 16450074.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    40. Sustained preconditioning induced by cardiac transgenesis with the tetracycline transactivator. Am J Physiol Heart Circ Physiol. 2006 Mar; 290(3):H1103-9. Turnbull L, Zhou HZ, Swigart PM, Turcato S, Karliner JS, Conklin BR, Simpson PC, Baker AJ. PMID: 16243914.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    41. Cardiac transgenic matrix metalloproteinase-2 expression directly induces impaired contractility. Cardiovasc Res. 2006 Feb 15; 69(3):688-96. Wang GY, Bergman MR, Nguyen AP, Turcato S, Swigart PM, Rodrigo MC, Simpson PC, Karliner JS, Lovett DH, Baker AJ. PMID: 16183043.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    42. Cardiac transgenesis with the tetracycline transactivator changes myocardial function and gene expression. Physiol Genomics. 2005 Jun 16; 22(1):118-26. McCloskey DT, Turnbull L, Swigart PM, Zambon AC, Turcato S, Joho S, Grossman W, Conklin BR, Simpson PC, Baker AJ. PMID: 15797971.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    43. Abnormal myocardial contraction in alpha(1A)- and alpha(1B)-adrenoceptor double-knockout mice. J Mol Cell Cardiol. 2003 Oct; 35(10):1207-16. McCloskey DT, Turnbull L, Swigart P, O'Connell TD, Simpson PC, Baker AJ. PMID: 14519431.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    44. Alpha 1-adrenergic receptor responses in alpha 1AB-AR knockout mouse hearts suggest the presence of alpha 1D-AR. Am J Physiol Heart Circ Physiol. 2003 Apr; 284(4):H1104-9. Turnbull L, McCloskey DT, O'Connell TD, Simpson PC, Baker AJ. PMID: 12595294.
      View in: PubMed   Mentions: 28     Fields:    Translation:Animals
    45. Alpha(1)-adrenoceptor subtypes mediate negative inotropy in myocardium from alpha(1A/C)-knockout and wild type mice. J Mol Cell Cardiol. 2002 Aug; 34(8):1007-17. McCloskey DT, Rokosh DG, O'Connell TD, Keung EC, Simpson PC, Baker AJ. PMID: 12234770.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    46. Abnormal contraction caused by expression of G(i)-coupled receptor in transgenic model of dilated cardiomyopathy. Am J Physiol Heart Circ Physiol. 2001 Apr; 280(4):H1653-9. Baker AJ, Redfern CH, Harwood MD, Simpson PC, Conklin BR. PMID: 11247776.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    47. Conditional expression of a Gi-coupled receptor causes ventricular conduction delay and a lethal cardiomyopathy. Proc Natl Acad Sci U S A. 2000 Apr 25; 97(9):4826-31. Redfern CH, Degtyarev MY, Kwa AT, Salomonis N, Cotte N, Nanevicz T, Fidelman N, Desai K, Vranizan K, Lee EK, Coward P, Shah N, Warrington JA, Fishman GI, Bernstein D, Baker AJ, Conklin BR. PMID: 10781088; PMCID: PMC18317.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    48. Role of slowed Ca(2+) transient decline in slowed relaxation during myocardial ischemia. J Mol Cell Cardiol. 1999 Sep; 31(9):1739-48. Halow JM, Figueredo VM, Shames DM, Camacho SA, Baker AJ. PMID: 10471357.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    49. Cellular and extracellular mechanisms causing myocardial stunning. J Am Coll Cardiol. 1999 Aug; 34(2):603-5. Baker AJ. PMID: 10440179.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    50. Ca2+ regulates the kinetics of tension development in intact cardiac muscle. Am J Physiol. 1998 09; 275(3):H744-50. Baker AJ, Figueredo VM, Keung EC, Camacho SA. PMID: 9724275.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    51. Chronic alcohol-induced changes in cardiac contractility are not due to changes in the cytosolic Ca2+ transient. Am J Physiol. 1998 07; 275(1):H122-30. Figueredo VM, Chang KC, Baker AJ, Camacho SA. PMID: 9688904.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    52. Force decline during muscle relaxation promotes calcium release to the cytosol. Am J Physiol. 1997 Jul; 273(1 Pt 1):C85-91. Baker AJ, Weiner MW. PMID: 9252445.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    53. Ca(2+)-force relationship of frog skeletal muscle: a dynamic model for parameter estimation. Am J Physiol. 1996 Dec; 271(6 Pt 1):C2062-71. Shames DM, Baker AJ, Weiner MW, Camacho SA. PMID: 8997209.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    54. Cytosolic and mitochondrial [Ca2+] in whole hearts using indo-1 acetoxymethyl ester: effects of high extracellular Ca2+. Biophys J. 1996 Jun; 70(6):2571-80. Schreur JH, Figueredo VM, Miyamae M, Shames DM, Baker AJ, Camacho SA. PMID: 8744296; PMCID: PMC1225238.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    55. The myosin catalytic domain does not rotate during the working power stroke. Biophys J. 1995 Sep; 69(3):994-9. Zhao L, Pate E, Baker AJ, Cooke R. PMID: 8519999; PMCID: PMC1236328.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    56. Effects of intracellular acidosis on Ca2+ activation, contraction, and relaxation of frog skeletal muscle. Am J Physiol. 1995 Jan; 268(1 Pt 1):C55-63. Baker AJ, Brandes R, Weiner MW. PMID: 7840160.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    57. Factors which influence alterations of phosphates and pH in exercising human skeletal muscle: measurement error, reproducibility, and effects of fasting, carbohydrate loading, and metabolic acidosis. Muscle Nerve. 1995 Jan; 18(1):60-7. Miller RG, Carson PJ, Moussavi RS, Green A, Baker A, Boska MD, Weiner MW. PMID: 7799999.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    58. Protein and acidosis alter calcium-binding and fluorescence spectra of the calcium indicator indo-1. Biophys J. 1994 Oct; 67(4):1646-54. Baker AJ, Brandes R, Schreur JH, Camacho SA, Weiner MW. PMID: 7819496; PMCID: PMC1225526.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    59. Metabolic and nonmetabolic components of fatigue monitored with 31P-NMR. Muscle Nerve. 1994 Sep; 17(9):1002-9. Baker AJ, Carson PJ, Miller RG, Weiner MW. PMID: 8065387.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    60. Energy use by contractile and noncontractile processes in skeletal muscle estimated by 31P-NMR. Am J Physiol. 1994 Mar; 266(3 Pt 1):C825-31. Baker AJ, Brandes R, Schendel TM, Trocha SD, Miller RG, Weiner MW. PMID: 8166246.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    61. Investigation of factors affecting fluorometric quantitation of cytosolic [Ca2+] in perfused hearts. Biophys J. 1993 Nov; 65(5):1983-93. Brandes R, Figueredo VM, Camacho SA, Baker AJ, Weiner MW. PMID: 8298028; PMCID: PMC1225934.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    62. Quantitation of cytosolic [Ca2+] in whole perfused rat hearts using Indo-1 fluorometry. Biophys J. 1993 Nov; 65(5):1973-82. Brandes R, Figueredo VM, Camacho SA, Baker AJ, Weiner MW. PMID: 8298027; PMCID: PMC1225933.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    63. Slow force recovery after long-duration exercise: metabolic and activation factors in muscle fatigue. J Appl Physiol (1985). 1993 May; 74(5):2294-300. Baker AJ, Kostov KG, Miller RG, Weiner MW. PMID: 8335559.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    64. Intracellular tetanic calcium signals are reduced in fatigue of whole skeletal muscle. Am J Physiol. 1993 Mar; 264(3 Pt 1):C577-82. Baker AJ, Longuemare MC, Brandes R, Weiner MW. PMID: 8460665.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    65. Improved preservation of skeletal muscle in amputated limbs using pulsatile hypothermic perfusion with University of Wisconsin solution. A preliminary study. J Bone Joint Surg Am. 1992 Oct; 74(9):1358-66. Gordon L, Levinsohn DG, Borowsky CD, Manojlovic RD, Sessler DI, Weiner MW, Baker AJ. PMID: 1429791.
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    66. Influence of human muscle length on energy transduction studied by 31P-NMR. J Appl Physiol (1985). 1992 Jul; 73(1):160-5. Baker AJ, Carson PJ, Green AT, Miller RG, Weiner MW. PMID: 1506363.
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    67. Fatigue and myalgia in AIDS patients. Neurology. 1991 Oct; 41(10):1603-7. Miller RG, Carson PJ, Moussavi RS, Green AT, Baker AJ, Weiner MW. PMID: 1922802.
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    68. Constant relationships between force, phosphate concentration, and pH in muscles with differential fatigability. Neurology. 1990 Dec; 40(12):1888-93. Weiner MW, Moussavi RS, Baker AJ, Boska MD, Miller RG. PMID: 2247239.
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    69. Investigations of muscle bioenergetics with 31P NMR. Invest Radiol. 1989 Dec; 24(12):1001-5. Baker AJ, Carson PJ, Miller RG, Weiner MW. PMID: 2691438.
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