Ari Green, MD

Title(s)Professor, Neurology
SchoolSchool of Medicine
Address675 Nelson Rising Lane
San Francisco CA 94158
Phone415-260-9674
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Biography 
    Collapse Education and Training
    Miami University BA/BS Economics/ Philosophy/Physics Medicine
    Duke University MD Medicine
    University of California, San Francisco Intern. Medicine
    University of California, San Francisco Residency Neurology
    University of California, San Francisco Fellowship Neuroimmunology
    University of California, San Francisco Fellowship Neuro-ophthalmology
    University of California, San FranciscoMCR Clinical Research
    Queen’s University BelfastVisiting FellowNeuropath (retina)
    Collapse Awards and Honors
    1990Edward and Mary Shepherd Scholar
    1991University Scholar leader award
    1991Silber fellowship American Cancer Society
    1994Magna Cum Laude with Honors
    1994President’s Distinguished Service Award
    1996Teaching/Service Award Franklinton County Schools
    1998  - 2000Howard Hughes Medical Institute Predoctoral Fellowship
    2005Chief Resident in Neurology
    2008NIH Loan repayment program recipient
    2005NIH Loan repayment program recipient
    2006AAN Foundation Research Fellow Award
    2008HHMI Early Clinician Scientist Award
    2009Debbie and Andy Rachleff Distinguished Professor in Neurology
    2012CTSI T1 Catalyst Award
    2012Harry Weaver Neuroscience Scholar (National MS Society)
    2015UCSF Distinguished Professors Dinner Keynote

    Collapse Overview 
    Collapse Overview
    Dr. Ari J Green is the Chief of the Division of Neuroimmunology and Glial Biology in the Department of Neurology at the University of California at San Francisco. His team consists of more than 20 laboratories and groups dedicated to discovering the causes of Multiple Sclerosis and related disorders; and to developing treatments as well as cures for these conditions. Dr. Green is also Medical Director of the UCSF MS and Neuroinflammation Center – one of the largest clinics of its kind in the United States with a broad focus on caring for patients with conditions in which immune dysregulation or inflammation play an important role. The clinic seeks to provide comprehensive, patient-centered care for people living with these diseases with a wide variety of ancillary services for diagnosis, monitoring and supporting patients and their families. Dr. Green’s laboratory is dedicated to the biological validation of potential biomarkers intended to measure remyelination and repair (as well as progression) in MS as a means to accelerate clinical trials for reparative treatments. His major scientific contributions include directing the first successful phase II clinical trial of a remyelinating agent for MS, developing methods for monitoring myelin repair, detailing the histopathological changes in the retina seen in MS, and describing the role of progranulin in the retina along with discovering a previously unknown retinal phenotype in progranulin-related frontotemporal dementia. His lab maintains an active interest in the developing and validating biomarkers for neurodegenerative disease generally and inflammatory diseases of the central nervous system in particular. He also co-directs the Program in Remyelination and Repair with Dr. Jonah Chan as well as the Neurodiagnostics Center in the Department of Neurology.

    Dr. Green completed medical school at Duke University School of Medicine in 2001 (during which time he had a Howard Hughes Medical Institute predoctoral fellowship with Drs. Jorge Oksenberg and Stephen L Hauser) and Internship in the Department of Medicine at UCSF in 2002. He completed Residency training at UCSF including Chief Residency in Neurology and post residency fellowships in Neuroimmunology under Dr. Stephen Hauser and Neuro-ophthalmology under Drs. William F. Hoyt and Kimberly Cockerham at UCSF. He then had a visiting fellowship at Queen’s University Belfast under Dame Ingrid Allen in Neuropathology. He was named the first AAN/NMSS Clinician Science Fellow in 2005 and received a Howard Hughes Clinician Scientist award from HHMI. He was named as the Debbie and Andy Rachleff Distinguished Professor of Neurology in 2009 and joined the Department of Ophthalmology at UCSF in 2011. He was a Harry Weaver Neuroscience Scholar and has served as Associate Editor for JAMA Neurology since 2017.

    The Division of Neuroimmunology and Glial Biology - since its inception under the leadership of Dr. Stephen Hauser in 1992 - has made major contributions to all aspects of the biology of MS and its treatment including defining the full genetic risk profile for MS, discovering the importance of B cell biology in MS, improving our understanding of adaptive immune processes in inflammatory diseases of the brain and making groundbreaking discoveries in therapeutics for repair and remyelination in MS and other demyelinating diseases. The group continues to be focused on breakthrough developments in the field including microbiome research, glial biology work, and working to uncover the triggers of MS and other inflammatory diseases of the CNS. Under Dr. Green’s leadership, the group has expanded its focus to investigate new methods for understanding infectious and inflammatory diseases of the brain as well as developmental and autoimmune disorders of the CNS that lead to neurological disability. The Division is also a leading force for the education of trainees in clinical care, scientific disciplines and graduate studies in all areas related to our clinical and research mission. We actively train clinical fellows, residents, students and community members in issues of importance to our patients and their families.

    Collapse Research 
    Collapse Research Activities and Funding
    Adelson Medical Research Foundation
    04-7023433Oct 1, 2019 - Sep 30, 2020
    Role: Co-Investigator
    Tracking Longitudinal Change in Presymptomatic Genetic Prion Disease (TLC-Pre-gPrD)
    NIH R01 AG062562-01Aug 1, 2019 - May 31, 2024
    Role: Co-Investigator
    Establishing VEP as a quantitative biomarker for remyelination using transgenic models for gain and loss of function
    NIH R01NS105741May 15, 2018 - Feb 28, 2023
    Role: Principal Investigator
    Functional validation of SERMs as remyelinating agents
    NMSS RG-1707-28564Apr 1, 2018 - Mar 31, 2021
    Role: Co-Investigator
    Goal:Functional Screening of GPCR Small Molecule Libraries for Remyelination Therapies
    NIH R01 NS095889Oct 1, 2016 - Sep 30, 2021
    Role: Co-Investigator
    Somatodendritic Inhibition of Oligodendrocyte Myelination
    NIH R01 NS062796Jun 1, 2016 - Feb 28, 2021
    Role: Co-Investigator
    The Four Repeat Tauopathy Neuroimaging Initiative
    NIH/NIA R01AG038791Mar 1, 2016 - Feb 28, 2021
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Distinctive waves of innate immune response in the retina in experimental autoimmune encephalomyelitis. JCI Insight. 2021 Jun 08; 6(11). Cruz-Herranz A, Oertel FC, Kim K, Cantó E, Timmons G, Sin JH, Devereux M, Baker N, Michel B, Schubert RD, Rani L, Cordano C, Baranzini SE, Green AJ. PMID: 34100385.
      View in: PubMed   Mentions: 1     Fields:    
    2. Artificial intelligence extension of the OSCAR-IB criteria. Ann Clin Transl Neurol. 2021 Jul; 8(7):1528-1542. Petzold A, Albrecht P, Balcer L, Bekkers E, Brandt AU, Calabresi PA, Deborah OG, Graves JS, Green A, Keane PA, Nij Bijvank JA, Sander JW, Paul F, Saidha S, Villoslada P, Wagner SK, Yeh EA, IMSVISUAL, ERN-EYE Consortium . PMID: 34008926.
      View in: PubMed   Mentions: 1     Fields:    
    3. Retinal imaging demonstrates reduced capillary density in clinically unimpaired APOE e4 gene carriers. Alzheimers Dement (Amst). 2021; 13(1):e12181. Elahi FM, Ashimatey SB, Bennett DJ, Walters SM, La Joie R, Jiang X, Wolf A, Cobigo Y, Staffaroni AM, Rosen HJ, Miller BL, Rabinovici GD, Kramer JH, Green AJ, Kashani AH. PMID: 34013017.
      View in: PubMed   Mentions:
    4. APOSTEL 2.0 Recommendations for Reporting Quantitative Optical Coherence Tomography Studies. Neurology. 2021 07 13; 97(2):68-79. Aytulun A, Cruz-Herranz A, Aktas O, Balcer LJ, Balk L, Barboni P, Blanco AA, Calabresi PA, Costello F, Sanchez-Dalmau B, DeBuc DC, Feltgen N, Finger RP, Frederiksen JL, Frohman E, Frohman T, Garway-Heath D, Gabilondo I, Graves JS, Green AJ, Hartung HP, Havla J, Holz FG, Imitola J, Kenney R, Klistorner A, Knier B, Korn T, Kolbe S, Krämer J, Lagrèze WA, Leocani L, Maier O, Martínez-Lapiscina EH, Meuth S, Outteryck O, Paul F, Petzold A, Pihl-Jensen G, Preiningerova JL, Rebolleda G, Ringelstein M, Saidha S, Schippling S, Schuman JS, Sergott RC, Toosy A, Villoslada P, Wolf S, Yeh EA, Yu-Wai-Man P, Zimmermann HG, Brandt AU, Albrecht P. PMID: 33910937.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Disability Outcomes in the N-MOmentum Trial of Inebilizumab in Neuromyelitis Optica Spectrum Disorder. Neurol Neuroimmunol Neuroinflamm. 2021 05; 8(3). Marignier R, Bennett JL, Kim HJ, Weinshenker BG, Pittock SJ, Wingerchuk D, Fujihara K, Paul F, Cutter GR, Green AJ, Aktas O, Hartung HP, Lublin FD, Williams IM, Drappa J, She D, Cimbora D, Rees W, Smith M, Ratchford JN, Katz E, Cree BAC, N-MOmentum Study Investigators . PMID: 33771837.
      View in: PubMed   Mentions:    Fields:    
    6. Sensitivity analysis of the primary endpoint from the N-MOmentum study of inebilizumab in NMOSD. Mult Scler. 2021 Feb 04; 1352458521988926. Cree BA, Bennett JL, Kim HJ, Weinshenker BG, Pittock SJ, Wingerchuk D, Fujihara K, Paul F, Cutter GR, Marignier R, Green AJ, Aktas O, Hartung HP, Williams IM, Drappa J, She D, Cimbora D, Rees W, Ratchford JN, Katz E. PMID: 33538237.
      View in: PubMed   Mentions:    Fields:    
    7. Underutilization of physical therapy for symptomatic women with MS during and following pregnancy. Mult Scler Relat Disord. 2021 Feb; 48:102703. Block VJ, Mestas O, Anderson A, Singh J, Wylie L, Guo CY, Green AJ, Gelfand JM, Bove R. PMID: 33387862.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Retinal INL Thickness in Multiple Sclerosis: A Mere Marker of Neurodegeneration? Ann Neurol. 2021 01; 89(1):192-193. Cordano C, Yiu HH, Oertel FC, University of California, San Francisco MS-EPIC Team , Gelfand JM, Hauser SL, Cree BAC, Green AJ. PMID: 33067847.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. Neurite Orientation Dispersion and Density Imaging for Assessing Acute Inflammation and Lesion Evolution in MS. AJNR Am J Neuroradiol. 2020 12; 41(12):2219-2226. Sacco S, Caverzasi E, Papinutto N, Cordano C, Bischof A, Gundel T, Cheng S, Asteggiano C, Kirkish G, Mallott J, Stern WA, Bastianello S, Bove RM, Gelfand JM, Goodin DS, Green AJ, Waubant E, Wilson MR, Zamvil SS, Cree BA, Hauser SL, Henry RG, University of California, San Francisco MS-EPIC Team . PMID: 33154077.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    10. Interocular Difference in Retinal Nerve Fiber Layer Thickness Predicts Optic Neuritis in Pediatric-Onset Multiple Sclerosis. J Neuroophthalmol. 2020 Oct 22. Waldman AT, Benson L, Sollee JR, Lavery AM, Liu GW, Green AJ, Waubant E, Heidary G, Conger D, Graves J, Greenberg B. PMID: 33105412.
      View in: PubMed   Mentions: 1     Fields:    
    11. Importance of Not MSing Cerebral White Matter Disease in Patients with Inflammatory Bowel Disease. Dig Dis Sci. 2020 09; 65(9):2527-2532. Regner EH, Green AJ, Bain JL, Kattah MG, Mahadevan U. PMID: 32651742.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Author Correction: Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation. Nat Immunol. 2020 Sep; 21(9):1135. Mendiola AS, Ryu JK, Bardehle S, Meyer-Franke A, Ang KK, Wilson C, Baeten KM, Hanspers K, Merlini M, Thomas S, Petersen MA, Williams A, Thomas R, Rafalski VA, Meza-Acevedo R, Tognatta R, Yan Z, Pfaff SJ, Machado MR, Bedard C, Coronado PER, Jiang X, Wang J, Pleiss MA, Green AJ, Zamvil SS, Pico AR, Bruneau BG, Arkin MR, Akassoglou K. PMID: 32661365.
      View in: PubMed   Mentions:    Fields:    
    13. A pathogenic and clonally expanded B cell transcriptome in active multiple sclerosis. Proc Natl Acad Sci U S A. 2020 09 15; 117(37):22932-22943. Ramesh A, Schubert RD, Greenfield AL, Dandekar R, Loudermilk R, Sabatino JJ, Koelzer MT, Tran EB, Koshal K, Kim K, Pröbstel AK, Banerji D, University of California, San Francisco MS-EPIC Team , Guo CY, Green AJ, Bove RM, DeRisi JL, Gelfand JM, Cree BAC, Zamvil SS, Baranzini SE, Hauser SL, Wilson MR. PMID: 32859762.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    14. Imaging correlates of visual function in multiple sclerosis. PLoS One. 2020; 15(8):e0235615. Caverzasi E, Cordano C, Zhu AH, Zhao C, Bischof A, Kirkish G, Bennett DJ, Devereux M, Baker N, Inman J, Yiu HH, Papinutto N, Gelfand JM, Cree BAC, Hauser SL, Henry RG, Green AJ. PMID: 32745132.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    15. The Spectrum of Neurologic Disease in the Severe Acute Respiratory Syndrome Coronavirus 2 Pandemic Infection: Neurologists Move to the Frontlines. JAMA Neurol. 2020 06 01; 77(6):679-680. Pleasure SJ, Green AJ, Josephson SA. PMID: 32275291.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCellsPHPublic Health
    16. Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation. Nat Immunol. 2020 05; 21(5):513-524. Mendiola AS, Ryu JK, Bardehle S, Meyer-Franke A, Ang KK, Wilson C, Baeten KM, Hanspers K, Merlini M, Thomas S, Petersen MA, Williams A, Thomas R, Rafalski VA, Meza-Acevedo R, Tognatta R, Yan Z, Pfaff SJ, Machado MR, Bedard C, Rios Coronado PE, Jiang X, Wang J, Pleiss MA, Green AJ, Zamvil SS, Pico AR, Bruneau BG, Arkin MR, Akassoglou K. PMID: 32284594.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    17. Protective effects of 4-aminopyridine in experimental optic neuritis and multiple sclerosis. Brain. 2020 04 01; 143(4):1127-1142. Dietrich M, Koska V, Hecker C, Göttle P, Hilla AM, Heskamp A, Lepka K, Issberner A, Hallenberger A, Baksmeier C, Steckel J, Balk L, Knier B, Korn T, Havla J, Martínez-Lapiscina EH, Solà-Valls N, Manogaran P, Olbert ED, Schippling S, Cruz-Herranz A, Yiu H, Button J, Caldito NG, von Gall C, Mausberg AK, Stettner M, Zimmermann HG, Paul F, Brandt AU, Küry P, Goebels N, Aktas O, Berndt C, Saidha S, Green AJ, Calabresi PA, Fischer D, Hartung HP, Albrecht P. PMID: 32293668.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    18. Fixational microsaccades: A quantitative and objective measure of disability in multiple sclerosis. Mult Scler. 2020 03; 26(3):343-353. Sheehy CK, Bensinger ES, Romeo A, Rani L, Stepien-Bernabe N, Shi B, Helft Z, Putnam N, Cordano C, Gelfand JM, Bove R, Stevenson SB, Green AJ. PMID: 32031464.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Monitoring retinal changes with optical coherence tomography predicts neuronal loss in experimental autoimmune encephalomyelitis. J Neuroinflammation. 2019 Nov 04; 16(1):203. Cruz-Herranz A, Dietrich M, Hilla AM, Yiu HH, Levin MH, Hecker C, Issberner A, Hallenberger A, Cordano C, Lehmann-Horn K, Balk LJ, Aktas O, Ingwersen J, von Gall C, Hartung HP, Zamvil SS, Fischer D, Albrecht P, Green AJ. PMID: 31684959.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    20. Inebilizumab for the treatment of neuromyelitis optica spectrum disorder (N-MOmentum): a double-blind, randomised placebo-controlled phase 2/3 trial. Lancet. 2019 10 12; 394(10206):1352-1363. Cree BAC, Bennett JL, Kim HJ, Weinshenker BG, Pittock SJ, Wingerchuk DM, Fujihara K, Paul F, Cutter GR, Marignier R, Green AJ, Aktas O, Hartung HP, Lublin FD, Drappa J, Barron G, Madani S, Ratchford JN, She D, Cimbora D, Katz E, N-MOmentum study investigators . PMID: 31495497.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCTClinical Trials
    21. Early complement genes are associated with visual system degeneration in multiple sclerosis. Brain. 2019 09 01; 142(9):2722-2736. Fitzgerald KC, Kim K, Smith MD, Aston SA, Fioravante N, Rothman AM, Krieger S, Cofield SS, Kimbrough DJ, Bhargava P, Saidha S, Whartenby KA, Green AJ, Mowry EM, Cutter GR, Lublin FD, Baranzini SE, De Jager PL, Calabresi PA. PMID: 31289819.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    22. Lessons from an unsuccessful therapeutic trial. Lancet Neurol. 2019 09; 18(9):808-810. Green AJ. PMID: 31285148.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. Personalizing medical care for patients with MS: Monitoring brainstem damage by infrared oculography. Neurology. 2019 05 14; 92(20):929-930. Villoslada P, Green AJ, Galetta S. PMID: 31004068.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Silent progression in disease activity-free relapsing multiple sclerosis. Ann Neurol. 2019 05; 85(5):653-666. University of California, San Francisco MS-EPIC Team , Cree BAC, Hollenbach JA, Bove R, Kirkish G, Sacco S, Caverzasi E, Bischof A, Gundel T, Zhu AH, Papinutto N, Stern WA, Bevan C, Romeo A, Goodin DS, Gelfand JM, Graves J, Green AJ, Wilson MR, Zamvil SS, Zhao C, Gomez R, Ragan NR, Rush GQ, Barba P, Santaniello A, Baranzini SE, Oksenberg JR, Henry RG, Hauser SL. PMID: 30851128.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    25. Association of Continuous Assessment of Step Count by Remote Monitoring With Disability Progression Among Adults With Multiple Sclerosis. JAMA Netw Open. 2019 03 01; 2(3):e190570. Block VJ, Bove R, Zhao C, Garcha P, Graves J, Romeo AR, Green AJ, Allen DD, Hollenbach JA, Olgin JE, Marcus GM, Pletcher MJ, Cree BAC, Gelfand JM. PMID: 30874777.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    26. Potential Benefits of Early Aggressive Treatment in Multiple Sclerosis. JAMA Neurol. 2019 03 01; 76(3):254-256. Green AJ. PMID: 30644966.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    27. Selective Estrogen Receptor Modulators Enhance CNS Remyelination Independent of Estrogen Receptors. J Neurosci. 2019 03 20; 39(12):2184-2194. Rankin KA, Mei F, Kim K, Shen YA, Mayoral SR, Desponts C, Lorrain DS, Green AJ, Baranzini SE, Chan JR, Bove R. PMID: 30696729.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    28. pRNFL as a marker of disability worsening in the medium/long term in patients with MS. Neurol Neuroimmunol Neuroinflamm. 2019 03; 6(2):e533. Cordano C, Nourbakhsh B, Devereux M, Damotte V, Bennett D, Hauser SL, Cree BAC, Gelfand JM, Green AJ. PMID: 30697584.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    29. Methods to Assess Ocular Motor Dysfunction in Multiple Sclerosis. J Neuroophthalmol. 2018 12; 38(4):488-493. Sheehy CK, Beaudry-Richard A, Bensinger E, Theis J, Green AJ. PMID: 30418331.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    30. Prion Seeds Distribute throughout the Eyes of Sporadic Creutzfeldt-Jakob Disease Patients. mBio. 2018 11 20; 9(6). Orrù CD, Soldau K, Cordano C, Llibre-Guerra J, Green AJ, Sanchez H, Groveman BR, Edland SD, Safar JG, Lin JH, Caughey B, Geschwind MD, Sigurdson CJ. PMID: 30459197.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    31. Clinic to in-home telemedicine reduces barriers to care for patients with MS or other neuroimmunologic conditions. Neurol Neuroimmunol Neuroinflamm. 2018 Nov; 5(6):e505. Bove R, Garcha P, Bevan CJ, Crabtree-Hartman E, Green AJ, Gelfand JM. PMID: 30775409.
      View in: PubMed   Mentions: 6     Fields:    
    32. Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity. Elife. 2018 09 11; 7. Schirmer L, Möbius W, Zhao C, Cruz-Herranz A, Ben Haim L, Cordano C, Shiow LR, Kelley KW, Sadowski B, Timmons G, Pröbstel AK, Wright JN, Sin JH, Devereux M, Morrison DE, Chang SM, Sabeur K, Green AJ, Nave KA, Franklin RJ, Rowitch DH. PMID: 30204081.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    33. Toward a low-cost, in-home, telemedicine-enabled assessment of disability in multiple sclerosis. Mult Scler. 2019 10; 25(11):1526-1534. Bove R, Bevan C, Crabtree E, Zhao C, Gomez R, Garcha P, Morrissey J, Dierkhising J, Green AJ, Hauser SL, Cree BA, Wallin MT, Gelfand JM. PMID: 30141729.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    34. Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing. JAMA Neurol. 2018 08 01; 75(8):947-955. Wilson MR, O'Donovan BD, Gelfand JM, Sample HA, Chow FC, Betjemann JP, Shah MP, Richie MB, Gorman MP, Hajj-Ali RA, Calabrese LH, Zorn KC, Chow ED, Greenlee JE, Blum JH, Green G, Khan LM, Banerji D, Langelier C, Bryson-Cahn C, Harrington W, Lingappa JR, Shanbhag NM, Green AJ, Brew BJ, Soldatos A, Strnad L, Doernberg SB, Jay CA, Douglas V, Josephson SA, DeRisi JL. PMID: 29710329.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    35. Reduced contrast sensitivity among older women is associated with increased risk of cognitive impairment. Ann Neurol. 2018 04; 83(4):730-738. Ward ME, Gelfand JM, Lui LY, Ou Y, Green AJ, Stone K, Pedula KL, Cummings SR, Yaffe K. PMID: 29518257.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    36. Rituximab before and during pregnancy: A systematic review, and a case series in MS and NMOSD. Neurol Neuroimmunol Neuroinflamm. 2018 May; 5(3):e453. Das G, Damotte V, Gelfand JM, Bevan C, Cree BAC, Do L, Green AJ, Hauser SL, Bove R. PMID: 29564373.
      View in: PubMed   Mentions: 34     Fields:    
    37. OCT is an alternative to MRI for monitoring MS - Commentary. Mult Scler. 2018 05; 24(6):705-706. Green AJ. PMID: 29552931.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    38. Multicenter reliability of semiautomatic retinal layer segmentation using OCT. Neurol Neuroimmunol Neuroinflamm. 2018 May; 5(3):e449. Oberwahrenbrock T, Traber GL, Lukas S, Gabilondo I, Nolan R, Songster C, Balk L, Petzold A, Paul F, Villoslada P, Brandt AU, Green AJ, Schippling S. PMID: 29552598.
      View in: PubMed   Mentions: 30     Fields:    
    39. Harnessing electronic medical records to advance research on multiple sclerosis. Mult Scler. 2019 03; 25(3):408-418. Damotte V, Lizée A, Tremblay M, Agrawal A, Khankhanian P, Santaniello A, Gomez R, Lincoln R, Tang W, Chen T, Lee N, Villoslada P, Hollenbach JA, Bevan CD, Graves J, Bove R, Goodin DS, Green AJ, Baranzini SE, Cree BA, Henry RG, Hauser SL, Gelfand JM, Gourraud PA. PMID: 29310490.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    40. Combating the Spread of Ineffective Medical Procedures: A Lesson Learned From Multiple Sclerosis. JAMA Neurol. 2018 01 01; 75(1):15-17. Green AJ, Kamel H, Josephson SA. PMID: 29150994.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    41. Cell-based therapeutic strategies for multiple sclerosis. Brain. 2017 11 01; 140(11):2776-2796. Scolding NJ, Pasquini M, Reingold SC, Cohen JA, International Conference on Cell-Based Therapies for Multiple Sclerosis , International Conference on Cell-Based Therapies for Multiple Sclerosis , International Conference on Cell-Based Therapies for Multiple Sclerosis . PMID: 29053779.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    42. Infliximab for the treatment of CNS sarcoidosis: A multi-institutional series. Neurology. 2017 Nov 14; 89(20):2092-2100. Gelfand JM, Bradshaw MJ, Stern BJ, Clifford DB, Wang Y, Cho TA, Koth LL, Hauser SL, Dierkhising J, Vu N, Sriram S, Moses H, Bagnato F, Kaufmann JA, Ammah DJ, Yohannes TH, Hamblin MJ, Venna N, Green AJ, Pawate S. PMID: 29030454.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    43. Clemastine fumarate as a remyelinating therapy for multiple sclerosis (ReBUILD): a randomised, controlled, double-blind, crossover trial. Lancet. 2017 Dec 02; 390(10111):2481-2489. Green AJ, Gelfand JM, Cree BA, Bevan C, Boscardin WJ, Mei F, Inman J, Arnow S, Devereux M, Abounasr A, Nobuta H, Zhu A, Friessen M, Gerona R, von Büdingen HC, Henry RG, Hauser SL, Chan JR. PMID: 29029896.
      View in: PubMed   Mentions: 87     Fields:    Translation:Humans
    44. Remyelinating Pharmacotherapies in Multiple Sclerosis. Neurotherapeutics. 2017 Oct; 14(4):894-904. Bove RM, Green AJ. PMID: 28948533.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    45. Systematic integration of biomedical knowledge prioritizes drugs for repurposing. Elife. 2017 09 22; 6. Himmelstein DS, Lizee A, Hessler C, Brueggeman L, Chen SL, Hadley D, Green A, Khankhanian P, Baranzini SE. PMID: 28936969.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    46. Retinal layer segmentation in multiple sclerosis: a systematic review and meta-analysis. Lancet Neurol. 2017 10; 16(10):797-812. Petzold A, Balcer LJ, Calabresi PA, Costello F, Frohman TC, Frohman EM, Martinez-Lapiscina EH, Green AJ, Kardon R, Outteryck O, Paul F, Schippling S, Vermersch P, Villoslada P, Balk LJ, ERN-EYE IMSVISUAL . PMID: 28920886.
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    47. Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4. J Vis Exp. 2017 08 21; (126). Sagan SA, Cruz-Herranz A, Spencer CM, Ho PP, Steinman L, Green AJ, Sobel RA, Zamvil SS. PMID: 28872108.
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    48. T cells targeting neuromyelitis optica autoantigen aquaporin-4 cause paralysis and visual system injury. J Nat Sci. 2017 May; 3(5). Cruz-Herranz A, Sagan SA, Sobel RA, Green AJ, Zamvil SS. PMID: 28748216.
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    49. Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis. Sci Transl Med. 2017 04 12; 9(385). Ward ME, Chen R, Huang HY, Ludwig C, Telpoukhovskaia M, Taubes A, Boudin H, Minami SS, Reichert M, Albrecht P, Gelfand JM, Cruz-Herranz A, Cordano C, Alavi MV, Leslie S, Seeley WW, Miller BL, Bigio E, Mesulam MM, Bogyo MS, Mackenzie IR, Staropoli JF, Cotman SL, Huang EJ, Gan L, Green AJ. PMID: 28404863.
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    50. Retinal thinning is uniquely associated with medial temporal lobe atrophy in neurologically normal older adults. Neurobiol Aging. 2017 03; 51:141-147. Casaletto KB, Ward ME, Baker NS, Bettcher BM, Gelfand JM, Li Y, Chen R, Dutt S, Miller B, Kramer JH, Green AJ. PMID: 28068565.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    51. Tolerance checkpoint bypass permits emergence of pathogenic T cells to neuromyelitis optica autoantigen aquaporin-4. Proc Natl Acad Sci U S A. 2016 12 20; 113(51):14781-14786. Sagan SA, Winger RC, Cruz-Herranz A, Nelson PA, Hagberg S, Miller CN, Spencer CM, Ho PP, Bennett JL, Levy M, Levin MH, Verkman AS, Steinman L, Green AJ, Anderson MS, Sobel RA, Zamvil SS. PMID: 27940915.
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    52. Whole-body positional manipulators for ocular imaging of anaesthetised mice and rats: a do-it-yourself guide. BMJ Open Ophthalmol. 2017; 1(1):e000008. Dietrich M, Cruz-Herranz A, Yiu H, Aktas O, Brandt AU, Hartung HP, Green A, Albrecht P. PMID: 29354694.
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    53. Accelerated remyelination during inflammatory demyelination prevents axonal loss and improves functional recovery. Elife. 2016 Sep 27; 5. Mei F, Lehmann-Horn K, Shen YA, Rankin KA, Stebbins KJ, Lorrain DS, Pekarek K, A Sagan S, Xiao L, Teuscher C, von Büdingen HC, Wess J, Lawrence JJ, Green AJ, Fancy SP, Zamvil SS, Chan JR. PMID: 27671734.
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    54. Long-term evolution of multiple sclerosis disability in the treatment era. Ann Neurol. 2016 10; 80(4):499-510. University of California, San Francisco MS-EPIC Team: , Cree BA, Gourraud PA, Oksenberg JR, Bevan C, Crabtree-Hartman E, Gelfand JM, Goodin DS, Graves J, Green AJ, Mowry E, Okuda DT, Pelletier D, von Büdingen HC, Zamvil SS, Agrawal A, Caillier S, Ciocca C, Gomez R, Kanner R, Lincoln R, Lizee A, Qualley P, Santaniello A, Suleiman L, Bucci M, Panara V, Papinutto N, Stern WA, Zhu AH, Cutter GR, Baranzini S, Henry RG, Hauser SL. PMID: 27464262.
      View in: PubMed   Mentions: 72     Fields:    Translation:Humans
    55. Identification of the Kappa-Opioid Receptor as a Therapeutic Target for Oligodendrocyte Remyelination. J Neurosci. 2016 07 27; 36(30):7925-35. Mei F, Mayoral SR, Nobuta H, Wang F, Desponts C, Lorrain DS, Xiao L, Green AJ, Rowitch D, Whistler J, Chan JR. PMID: 27466337.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    56. Sex differences and subclinical retinal injury in pediatric-onset MS. Mult Scler. 2017 Mar; 23(3):447-455. Graves JS, Chohan H, Cedars B, Arnow S, Yiu H, Waubant E, Green A. PMID: 27306618.
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    57. The APOSTEL recommendations for reporting quantitative optical coherence tomography studies. Neurology. 2016 Jun 14; 86(24):2303-9. Cruz-Herranz A, Balk LJ, Oberwahrenbrock T, Saidha S, Martinez-Lapiscina EH, Lagreze WA, Schuman JS, Villoslada P, Calabresi P, Balcer L, Petzold A, Green AJ, Paul F, Brandt AU, Albrecht P, IMSVISUAL consortium . PMID: 27225223.
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    58. Timing of retinal neuronal and axonal loss in MS: a longitudinal OCT study. J Neurol. 2016 Jul; 263(7):1323-31. Balk LJ, Cruz-Herranz A, Albrecht P, Arnow S, Gelfand JM, Tewarie P, Killestein J, Uitdehaag BM, Petzold A, Green AJ. PMID: 27142714.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    59. Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: a cohort study. Lancet Neurol. 2016 May; 15(6):574-84. Martinez-Lapiscina EH, Arnow S, Wilson JA, Saidha S, Preiningerova JL, Oberwahrenbrock T, Brandt AU, Pablo LE, Guerrieri S, Gonzalez I, Outteryck O, Mueller AK, Albrecht P, Chan W, Lukas S, Balk LJ, Fraser C, Frederiksen JL, Resto J, Frohman T, Cordano C, Zubizarreta I, Andorra M, Sanchez-Dalmau B, Saiz A, Bermel R, Klistorner A, Petzold A, Schippling S, Costello F, Aktas O, Vermersch P, Oreja-Guevara C, Comi G, Leocani L, Garcia-Martin E, Paul F, Havrdova E, Frohman E, Balcer LJ, Green AJ, Calabresi PA, Villoslada P, IMSVISUAL consortium . PMID: 27011339.
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    60. The challenge of comorbidity in clinical trials for multiple sclerosis. Neurology. 2016 Apr 12; 86(15):1437-1445. Marrie RA, Miller A, Sormani MP, Thompson A, Waubant E, Trojano M, O'Connor P, Reingold S, Cohen JA, attendees of the International Workshop on Comorbidity in Multiple Sclerosis . PMID: 26888986.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    61. Recommendations for observational studies of comorbidity in multiple sclerosis. Neurology. 2016 Apr 12; 86(15):1446-1453. Marrie RA, Miller A, Sormani MP, Thompson A, Waubant E, Trojano M, O'Connor P, Fiest K, Reider N, Reingold S, Cohen JA, attendees of the International Workshop on Comorbidity in Multiple Sclerosis . PMID: 26865523.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    62. Association Between Thoracic Spinal Cord Gray Matter Atrophy and Disability in Multiple Sclerosis. JAMA Neurol. 2015 Aug; 72(8):897-904. Schlaeger R, Papinutto N, Zhu AH, Lobach IV, Bevan CJ, Bucci M, Castellano A, Gelfand JM, Graves JS, Green AJ, Jordan KM, Keshavan A, Panara V, Stern WA, von Büdingen HC, Waubant E, Goodin DS, Cree BA, Hauser SL, Henry RG. PMID: 26053119.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    63. Retinal damage and vision loss in African American multiple sclerosis patients. Ann Neurol. 2015 Feb; 77(2):228-36. Kimbrough DJ, Sotirchos ES, Wilson JA, Al-Louzi O, Conger A, Conger D, Frohman TC, Saidha S, Green AJ, Frohman EM, Balcer LJ, Calabresi PA. PMID: 25382184.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    64. Encephalitis of unclear origin diagnosed by brain biopsy: a diagnostic challenge. JAMA Neurol. 2015 Jan; 72(1):66-72. Gelfand JM, Genrich G, Green AJ, Tihan T, Cree BA. PMID: 25365755.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    65. The best basic science paper in MS in 2013: Antimuscarinic therapies in remyelination. Mult Scler. 2014 Dec; 20(14):1814-6. Green AJ. PMID: 25392329.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    66. Precision medicine in chronic disease management: The multiple sclerosis BioScreen. Ann Neurol. 2014 Nov; 76(5):633-42. Gourraud PA, Henry RG, Cree BA, Crane JC, Lizee A, Olson MP, Santaniello AV, Datta E, Zhu AH, Bevan CJ, Gelfand JM, Graves JS, Goodin DS, Green AJ, von Büdingen HC, Waubant E, Zamvil SS, Crabtree-Hartman E, Nelson S, Baranzini SE, Hauser SL. PMID: 25263997.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    67. Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD. J Exp Med. 2014 Sep 22; 211(10):1937-45. Ward ME, Taubes A, Chen R, Miller BL, Sephton CF, Gelfand JM, Minami S, Boscardin J, Martens LH, Seeley WW, Yu G, Herz J, Filiano AJ, Arrant AE, Roberson ED, Kraft TW, Farese RV, Green A, Gan L. PMID: 25155018.
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    68. Spinal cord gray matter atrophy correlates with multiple sclerosis disability. Ann Neurol. 2014 Oct; 76(4):568-80. Schlaeger R, Papinutto N, Panara V, Bevan C, Lobach IV, Bucci M, Caverzasi E, Gelfand JM, Green AJ, Jordan KM, Stern WA, von Büdingen HC, Waubant E, Zhu AH, Goodin DS, Cree BA, Hauser SL, Henry RG. PMID: 25087920.
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    69. Magnetic resonance imaging correlates of clinical outcomes in early multiple sclerosis. Mult Scler Relat Disord. 2014 Nov; 3(6):720-7. Maghzi AH, Revirajan N, Julian LJ, Spain R, Mowry EM, Liu S, Jin C, Green AJ, McCulloch CE, Pelletier D, Waubant E. PMID: 25891551.
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    70. Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis. Nat Med. 2014 Aug; 20(8):954-960. Mei F, Fancy SPJ, Shen YA, Niu J, Zhao C, Presley B, Miao E, Lee S, Mayoral SR, Redmond SA, Etxeberria A, Xiao L, Franklin RJM, Green A, Hauser SL, Chan JR. PMID: 24997607.
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    71. Retinal architecture and mfERG: Optic nerve head component response characteristics in MS. Neurology. 2014 May 27; 82(21):1888-96. Schnurman ZS, Frohman TC, Beh SC, Conger D, Conger A, Saidha S, Galetta S, Calabresi PA, Green AJ, Balcer LJ, Frohman EM. PMID: 24789865.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    72. Reply: Microcysts in the inner nuclear layer from optic atrophy are caused by retrograde trans-synaptic degeneration combined with vitreous traction on the retinal surface. Brain. 2013 Nov; 136(Pt 11):e261. Green AJ, Schwartz D, Gelfand J. PMID: 23872367.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    73. Optic nerve head component responses of the multifocal electroretinogram in MS. Neurology. 2013 Aug 06; 81(6):545-51. Frohman TC, Beh SC, Saidha S, Schnurman Z, Conger D, Conger A, Ratchford JN, Lopez C, Galetta SL, Calabresi PA, Balcer LJ, Green AJ, Frohman EM. PMID: 23825172.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    74. Microcystic inner nuclear layer abnormalities and neuromyelitis optica. JAMA Neurol. 2013 May; 70(5):629-33. Gelfand JM, Cree BA, Nolan R, Arnow S, Green AJ. PMID: 23529376.
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    75. Reply: Microcystic macular degeneration from optic neuropathy: not inflammatory, not trans-synaptic degeneration. Brain. 2013 Jul; 136(Pt 7):e240. Gelfand JM, Green AJ. PMID: 23650224.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    76. Getting beyond the ganglion cell: morphometric adjustments for retinal optical coherence tomography in multiple sclerosis. JAMA Neurol. 2013 Jan; 70(1):13-5. Green AJ. PMID: 23318509.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    77. Fingolimod treatment in multiple sclerosis leads to increased macular volume. Neurology. 2013 Jan 08; 80(2):139-44. Nolan R, Gelfand JM, Green AJ. PMID: 23223539.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    78. Microcystic macular oedema, thickness of the inner nuclear layer of the retina, and disease characteristics in multiple sclerosis: a retrospective study. Lancet Neurol. 2012 Nov; 11(11):963-72. Saidha S, Sotirchos ES, Ibrahim MA, Crainiceanu CM, Gelfand JM, Sepah YJ, Ratchford JN, Oh J, Seigo MA, Newsome SD, Balcer LJ, Frohman EM, Green AJ, Nguyen QD, Calabresi PA. PMID: 23041237.
      View in: PubMed   Mentions: 94     Fields:    Translation:HumansCells
    79. Retinal axonal loss begins early in the course of multiple sclerosis and is similar between progressive phenotypes. PLoS One. 2012; 7(5):e36847. Gelfand JM, Goodin DS, Boscardin WJ, Nolan R, Cuneo A, Green AJ. PMID: 22666330.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    80. Microcystic macular oedema in multiple sclerosis is associated with disease severity. Brain. 2012 Jun; 135(Pt 6):1786-93. Gelfand JM, Nolan R, Schwartz DM, Graves J, Green AJ. PMID: 22539259.
      View in: PubMed   Mentions: 98     Fields:    Translation:Humans
    81. Will the real optic nerve sheath please stand up? J Ultrasound Med. 2012 Jan; 31(1):130-1. Teismann NA, Lenaghan P, Stein J, Green A. PMID: 22215781.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    82. Switching multiple sclerosis patients with breakthrough disease to second-line therapy. PLoS One. 2011 Feb 03; 6(2):e16664. Castillo-Trivino T, Mowry EM, Gajofatto A, Chabas D, Crabtree-Hartman E, Cree BA, Goodin DS, Green AJ, Okuda DT, Pelletier D, Zamvil SS, Vittinghoff E, Waubant E. PMID: 21304907.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    83. Heterogeneous patterns of tissue injury in NARP syndrome. J Neurol. 2011 Mar; 258(3):440-8. Gelfand JM, Duncan JL, Racine CA, Gillum LA, Chin CT, Zhang Y, Zhang Q, Wong LJ, Roorda A, Green AJ. PMID: 20953793.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    84. Optical coherence tomography: a sign of the times. Neurology. 2010 Oct 12; 75(15):1312-3. Green AJ. PMID: 20826713.
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    85. Optical coherence tomography in multiple sclerosis: a systematic review and meta-analysis. Lancet Neurol. 2010 Sep; 9(9):921-32. Petzold A, de Boer JF, Schippling S, Vermersch P, Kardon R, Green A, Calabresi PA, Polman C. PMID: 20723847.
      View in: PubMed   Mentions: 155     Fields:    Translation:Humans
    86. Ocular pathology in multiple sclerosis: retinal atrophy and inflammation irrespective of disease duration. Brain. 2010 Jun; 133(Pt 6):1591-601. Green AJ, McQuaid S, Hauser SL, Allen IV, Lyness R. PMID: 20410146.
      View in: PubMed   Mentions: 123     Fields:    Translation:Humans
    87. Understanding pseudo: the symptoms are real, the cause is unclear. Neurology. 2009 May 12; 72(19):1626-7. Green AJ. PMID: 19246422.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    88. Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Hum Mol Genet. 2009 Feb 15; 18(4):767-78. Baranzini SE, Wang J, Gibson RA, Galwey N, Naegelin Y, Barkhof F, Radue EW, Lindberg RL, Uitdehaag BM, Johnson MR, Angelakopoulou A, Hall L, Richardson JC, Prinjha RK, Gass A, Geurts JJ, Kragt J, Sombekke M, Vrenken H, Qualley P, Lincoln RR, Gomez R, Caillier SJ, George MF, Mousavi H, Guerrero R, Okuda DT, Cree BA, Green AJ, Waubant E, Goodin DS, Pelletier D, Matthews PM, Hauser SL, Kappos L, Polman CH, Oksenberg JR. PMID: 19010793.
      View in: PubMed   Mentions: 178     Fields:    Translation:Humans
    89. Pediatric multiple sclerosis. NeuroRx. 2006 Apr; 3(2):264-75. Chabas D, Green AJ, Waubant E. PMID: 16554264.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    90. Progressive multifocal leukoencephalopathy in a patient treated with natalizumab. N Engl J Med. 2005 Jul 28; 353(4):375-81. Langer-Gould A, Atlas SW, Green AJ, Bollen AW, Pelletier D. PMID: 15947078.
      View in: PubMed   Mentions: 314     Fields:    Translation:HumansCells
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