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Assessing Large Language Models for Oncology Data Inference From Radiology Reports. JCO Clin Cancer Inform. 2024 Dec; 8:e2400126.
Chen LC, Zack T, Demirci A, Sushil M, Miao B, Kasap C, Butte A, Collisson EA, Hong JC. PMID: 39661914.
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PubMed Mentions: Fields:
Translation:
Humans
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Repurposing an epithelial sodium channel inhibitor as a therapy for murine and human skin inflammation. Sci Transl Med. 2024 Dec 11; 16(777):eade5915.
Winge MCG, Nasrallah M, Jackrazi LV, Guo KQ, Fuhriman JM, Szafran R, Ramanathan M, Gurevich I, Nguyen NT, Siprashvili Z, Inayathullah M, Rajadas J, Porter DF, Khavari PA, Butte AJ, Marinkovich MP. PMID: 39661704.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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California Stress, Trauma, and Resilience Study (CalSTARS) protocol: A multiomics-based cross-sectional investigation and randomized controlled trial to elucidate the biology of ACEs and test a precision intervention for reducing stress and enhancing resilience. Stress. 2024 Jan; 27(1):2401788.
Kim LY, Schüssler-Fiorenza Rose SM, Mengelkoch S, Moriarity DP, Gassen J, Alley JC, Roos LG, Jiang T, Alavi A, Thota DD, Zhang X, Perelman D, Kodish T, Krupnick JL, May M, Bowman K, Hua J, Liao YJ, Lieberman AF, Butte AJ, Lester P, Thyne SM, Hilton JF, Snyder MP, Slavich GM. PMID: 39620249.
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PubMed Mentions:
1 Fields:
Translation:
HumansCTClinical Trials
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Revealing the impact of social circumstances on the selection of cancer therapy through natural language processing of social work notes. JAMIA Open. 2024 Dec; 7(4):ooae073.
Sun S, Zack T, Williams CYK, Butte AJ, Sushil M. PMID: 39399272; PMCID: PMC11470153.
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PubMed Mentions:
1
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Evaluating the use of large language models to provide clinical recommendations in the Emergency Department. Nat Commun. 2024 Oct 08; 15(1):8236.
Williams CYK, Miao BY, Kornblith AE, Butte AJ. PMID: 39379357; PMCID: PMC11461960.
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PubMed Mentions: Fields:
Translation:
Humans
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A comparative study of large language model-based zero-shot inference and task-specific supervised classification of breast cancer pathology reports. J Am Med Inform Assoc. 2024 Oct 01; 31(10):2315-2327.
Sushil M, Zack T, Mandair D, Zheng Z, Wali A, Yu YN, Quan Y, Lituiev D, Butte AJ. PMID: 38900207; PMCID: PMC11413420.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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The evolution of computational research in a data-centric world. Cell. 2024 Aug 22; 187(17):4449-4457.
Deshpande D, Chhugani K, Ramesh T, Pellegrini M, Shiffman S, Abedalthagafi MS, Alqahtani S, Ye J, Liu XS, Leek JT, Brazma A, Ophoff RA, Rao G, Butte AJ, Moore JH, Katritch V, Mangul S. PMID: 39178828.
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PubMed Mentions: Fields:
Translation:
Humans
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Modernizing the Data Infrastructure for Clinical Research to Meet Evolving Demands for Evidence. JAMA. 2024 08 05.
Franklin JB, Marra C, Abebe KZ, Butte AJ, Cook DJ, Esserman L, Fleisher LA, Grossman CI, Kass NE, Krumholz HM, Rowan K, Abernethy AP, JAMA Summit on Clinical Trials Participants. PMID: 39102333.
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PubMed Mentions: Fields:
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Enhancing emergency department charting: Using Generative Pre-trained Transformer-4 (GPT-4) to identify laceration repairs. Acad Emerg Med. 2024 Jul 31.
Bains JK, Williams CYK, Johnson D, Schwartz H, Sabbineni N, Butte AJ, Kornblith AE. PMID: 39082468.
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PubMed Mentions: Fields:
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Single-cell RNA-Seq analysis reveals cell subsets and gene signatures associated with rheumatoid arthritis disease activity. JCI Insight. 2024 Jul 02; 9(16).
Binvignat M, Miao BY, Wibrand C, Yang MM, Rychkov D, Flynn E, Nititham J, Tamaki W, Khan U, Carvidi A, Krueger M, Niemi E, Sun Y, Fragiadakis GK, Sellam J, Mariotti-Ferrandiz E, Klatzmann D, Gross AJ, Ye CJ, Butte AJ, Criswell LA, Nakamura MC, Sirota M. PMID: 38954480; PMCID: PMC11343607.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Transforming Cardiovascular Care With Artificial Intelligence: From Discovery to Practice: JACC State-of-the-Art Review. J Am Coll Cardiol. 2024 Jul 02; 84(1):97-114.
Khera R, Oikonomou EK, Nadkarni GN, Morley JR, Wiens J, Butte AJ, Topol EJ. PMID: 38925729.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Use of a Large Language Model to Assess Clinical Acuity of Adults in the Emergency Department. JAMA Netw Open. 2024 May 01; 7(5):e248895.
Williams CYK, Zack T, Miao BY, Sushil M, Wang M, Kornblith AE, Butte AJ. PMID: 38713466; PMCID: PMC11077390.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Ethical and regulatory challenges of large language models in medicine. Lancet Digit Health. 2024 Jun; 6(6):e428-e432.
Ong JCL, Chang SY, William W, Butte AJ, Shah NH, Chew LST, Liu N, Doshi-Velez F, Lu W, Savulescu J, Ting DSW. PMID: 38658283.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Learning epistatic polygenic phenotypes with Boolean interactions. PLoS One. 2024; 19(4):e0298906.
Behr M, Kumbier K, Cordova-Palomera A, Aguirre M, Ronen O, Ye C, Ashley E, Butte AJ, Arnaout R, Brown B, Priest J, Yu B. PMID: 38625909; PMCID: PMC11020961.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Evaluating large language models as agents in the clinic. NPJ Digit Med. 2024 Apr 03; 7(1):84.
Mehandru N, Miao BY, Almaraz ER, Sushil M, Butte AJ, Alaa A. PMID: 38570554; PMCID: PMC10991271.
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PubMed Mentions:
8
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Accurate, Robust, and Scalable Machine Abstraction of Mayo Endoscopic Subscores From Colonoscopy Reports. Inflamm Bowel Dis. 2024 Mar 26.
Silverman AL, Bhasuran B, Mosenia A, Yasini F, Ramasamy G, Banerjee I, Gupta S, Mardirossian T, Narain R, Sewell J, Butte AJ, Rudrapatna VA. PMID: 38533919.
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PubMed Mentions: Fields:
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Real-world effectiveness of ustekinumab and vedolizumab in TNF-exposed pediatric patients with ulcerative colitis. J Pediatr Gastroenterol Nutr. 2024 May; 78(5):1126-1134.
Patel PV, Zhang A, Bhasuran B, Ravindranath VG, Heyman MB, Verstraete SG, Butte AJ, Rosen MJ, Rudrapatna VA, ImproveCareNow Pediatric IBD Learning Health System. PMID: 38482890; PMCID: PMC11065561.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Algorithmic Identification of Treatment-Emergent Adverse Events From Clinical Notes Using Large Language Models: A Pilot Study in Inflammatory Bowel Disease. Clin Pharmacol Ther. 2024 Jun; 115(6):1391-1399.
Silverman AL, Sushil M, Bhasuran B, Ludwig D, Buchanan J, Racz R, Parakala M, El-Kamary S, Ahima O, Belov A, Choi L, Billings M, Li Y, Habal N, Liu Q, Tiwari J, Butte AJ, Rudrapatna VA. PMID: 38459719; PMCID: PMC11090709.
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PubMed Mentions:
2 Fields:
Translation:
Humans
-
To do no harm - and the most good - with AI in health care. Nat Med. 2024 Mar; 30(3):623-627.
Goldberg CB, Adams L, Blumenthal D, Brennan PF, Brown N, Butte AJ, Cheatham M, deBronkart D, Dixon J, Drazen J, Evans BJ, Hoffman SM, Holmes C, Lee P, Manrai AK, Omenn GS, Perlin JB, Ramoni R, Sapiro G, Sarkar R, Sood H, Vayena E, Kohane IS, RAISE Consortium. PMID: 38388841.
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PubMed Mentions:
15 Fields:
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Characterisation of digital therapeutic clinical trials: a systematic review with natural language processing. Lancet Digit Health. 2024 Mar; 6(3):e222-e229.
Miao BY, Sushil M, Xu A, Wang M, Arneson D, Berkley E, Subash M, Vashisht R, Rudrapatna V, Butte AJ. PMID: 38395542; PMCID: PMC11074920.
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PubMed Mentions:
2 Fields:
Translation:
Humans
-
CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods. Genome Biol. 2024 02 22; 25(1):53.
Critical Assessment of Genome Interpretation Consortium. PMID: 38389099; PMCID: PMC10882881.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Predictive Modeling of Drug-Related Adverse Events with Real-World Data: A Case Study of Linezolid Hematologic Outcomes. Clin Pharmacol Ther. 2024 04; 115(4):847-859.
Patel A, Doernberg SB, Zack T, Butte AJ, Radtke KK. PMID: 38345264.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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A comparative study of zero-shot inference with large language models and supervised modeling in breast cancer pathology classification. Res Sq. 2024 Feb 06.
Sushil M, Zack T, Mandair D, Zheng Z, Wali A, Yu YN, Quan Y, Butte AJ. PMID: 38405831; PMCID: PMC10889046.
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PubMed Mentions:
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The Reporting Quality of Machine Learning Studies on Pediatric Diabetes Mellitus: Systematic Review. J Med Internet Res. 2024 Jan 19; 26:e47430.
Zrubka Z, Kertész G, Gulácsi L, Czere J, Hölgyesi Á, Nezhad HM, Mosavi A, Kovács L, Butte AJ, Péntek M. PMID: 38241075; PMCID: PMC10837761.
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PubMed Mentions: Fields:
Translation:
Humans
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Cross-institution natural language processing for reliable clinical association studies: a methodological exploration. J Clin Epidemiol. 2024 Mar; 167:111258.
Sushil M, Butte AJ, Schuit E, van Smeden M, Leeuwenberg AM. PMID: 38219811.
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PubMed Mentions:
1 Fields:
Translation:
Humans
-
Topic modeling on clinical social work notes for exploring social determinants of health factors. JAMIA Open. 2024 Apr; 7(1):ooad112.
Sun S, Zack T, Williams CYK, Sushil M, Butte AJ. PMID: 38223407; PMCID: PMC10788143.
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PubMed Mentions:
2
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Assessing the potential of GPT-4 to perpetuate racial and gender biases in health care: a model evaluation study. Lancet Digit Health. 2024 01; 6(1):e12-e22.
Zack T, Lehman E, Suzgun M, Rodriguez JA, Celi LA, Gichoya J, Jurafsky D, Szolovits P, Bates DW, Abdulnour RE, Butte AJ, Alsentzer E. PMID: 38123252.
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PubMed Mentions:
44 Fields:
Translation:
Humans
-
Epistasis regulates genetic control of cardiac hypertrophy. Res Sq. 2023 Nov 20.
Wang Q, Tang TM, Youlton N, Weldy CS, Kenney AM, Ronen O, Hughes JW, Chin ET, Sutton SC, Agarwal A, Li X, Behr M, Kumbier K, Moravec CS, Tang WHW, Margulies KB, Cappola TP, Butte AJ, Arnaout R, Brown JB, Priest JR, Parikh VN, Yu B, Ashley EA. PMID: 38045390; PMCID: PMC10690313.
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PubMed Mentions:
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Telehealth and Mobile Health: Case Study for Understanding and Anticipating Emerging Science and Technology. NAM Perspect. 2023; 2023.
Mathews D, Abernethy A, Butte AJ, Ginsburg P, Kocher B, Levy L, Novelli C, Sandy L, Smee J, Fabi R, Offodile AC, Sherkow JS, Sullenger RD, Freiling E, Balatbat C. PMID: 38812841; PMCID: PMC11136501.
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PubMed Mentions:
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Neurotechnology and Noninvasive Neuromodulation: Case Study for Understanding and Anticipating Emerging Science and Technology. NAM Perspect. 2023; 2023.
Mathews D, Abernethy A, Butte AJ, Enriquez J, Kocher B, Lisanby SH, Persons TM, Fabi R, Offodile AC, Sherkow JS, Sullenger RD, Freiling E, Balatbat C. PMID: 38812840; PMCID: PMC11136498.
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PubMed Mentions:
1
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Sequential regression and simulation: a method for estimating causal effects from heterogeneous clinical trials without a common control group. BMC Med Res Methodol. 2023 10 03; 23(1):218.
Rudrapatna VA, Ravindranath VG, Arneson DV, Mosenia A, Butte AJ, Wang S. PMID: 37789257; PMCID: PMC10546672.
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PubMed Mentions:
1 Fields:
Translation:
Humans
-
Second-Line Pharmaceutical Treatments for Patients with Type 2 Diabetes. JAMA Netw Open. 2023 10 02; 6(10):e2336613.
Vashisht R, Patel A, Dahm L, Han C, Medders KE, Mowers R, Byington CL, Koliwad SK, Butte AJ. PMID: 37782497; PMCID: PMC10546239.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Artificial Intelligence-From Starting Pilots to Scalable Privilege. JAMA Oncol. 2023 10 01; 9(10):1341-1342.
Butte AJ. PMID: 37615950.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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The promise of digital healthcare technologies. Front Public Health. 2023; 11:1196596.
Yeung AWK, Torkamani A, Butte AJ, Glicksberg BS, Schuller B, Rodriguez B, Ting DSW, Bates D, Schaden E, Peng H, Willschke H, van der Laak J, Car J, Rahimi K, Celi LA, Banach M, Kletecka-Pulker M, Kimberger O, Eils R, Islam SMS, Wong ST, Wong TY, Gao W, Brunak S, Atanasov AG. PMID: 37822534; PMCID: PMC10562722.
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PubMed Mentions:
15 Fields:
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AI in Medicine-JAMA's Focus on Clinical Outcomes, Patient-Centered Care, Quality, and Equity. JAMA. 2023 09 05; 330(9):818-820.
Khera R, Butte AJ, Berkwits M, Hswen Y, Flanagin A, Park H, Curfman G, Bibbins-Domingo K. PMID: 37566406.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Development of a Machine Learning Model of Postoperative Acute Kidney Injury Using Non-Invasive Time-Sensitive Intraoperative Predictors. Bioengineering (Basel). 2023 Aug 05; 10(8).
Zamirpour S, Hubbard AE, Feng J, Butte AJ, Pirracchio R, Bishara A. PMID: 37627817; PMCID: PMC10451203.
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PubMed Mentions:
1
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Mammary duct luminal epithelium controls adipocyte thermogenic programme. Nature. 2023 Aug; 620(7972):192-199.
Patel S, Sparman NZR, Arneson D, Alvarsson A, Santos LC, Duesman SJ, Centonze A, Hathaway E, Ahn IS, Diamante G, Cely I, Cho CH, Talari NK, Rajbhandari AK, Goedeke L, Wang P, Butte AJ, Blanpain C, Chella Krishnan K, Lusis AJ, Stanley SA, Yang X, Rajbhandari P. PMID: 37495690; PMCID: PMC10529063.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
A certified de-identification system for all clinical text documents for information extraction at scale. JAMIA Open. 2023 Oct; 6(3):ooad045.
Radhakrishnan L, Schenk G, Muenzen K, Oskotsky B, Ashouri Choshali H, Plunkett T, Israni S, Butte AJ. PMID: 37416449; PMCID: PMC10320112.
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PubMed Mentions:
7
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ALK Inhibitor Treatment Patterns and Outcomes in Real-World Patients with ALK-Positive Non-Small-Cell Lung Cancer: A Retrospective Cohort Study. Target Oncol. 2023 Jul; 18(4):571-583.
Wang M, Slatter S, Sussell J, Lin CW, Ogale S, Datta D, Butte AJ, Bazhenova L, Rudrapatna VA. PMID: 37341856; PMCID: PMC10345061.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Bottom-up and top-down paradigms of artificial intelligence research approaches to healthcare data science using growing real-world big data. J Am Med Inform Assoc. 2023 06 20; 30(7):1323-1332.
Wang M, Sushil M, Miao BY, Butte AJ. PMID: 37187158; PMCID: PMC10280344.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Novel computational methods on electronic health record yields new estimates of transfusion-associated circulatory overload in populations enriched with high-risk patients. Transfusion. 2023 07; 63(7):1298-1309.
Wang M, Goldgof GM, Patel A, Whitaker B, Belov A, Chan B, Phelps E, Rubin B, Anderson S, Butte AJ. PMID: 37248741; PMCID: PMC10449535.
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PubMed Mentions: Fields:
Translation:
Humans
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Machine-Learning Algorithm to Improve Cohort Identification in Interstitial Lung Disease. Am J Respir Crit Care Med. 2023 05 15; 207(10):1398-1401.
Farrand E, Gologorskaya O, Mills H, Radhakrishnan L, Collard HR, Butte AJ. PMID: 36943196; PMCID: PMC10595454.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Serum tryptophan metabolites are associated with erosive hand osteoarthritis and pain: results from the DIGICOD cohort. Osteoarthritis Cartilage. 2023 08; 31(8):1132-1143.
Binvignat M, Emond P, Mifsud F, Miao B, Courties A, Lefèvre A, Maheu E, Crema MD, Klatzmann D, Kloppenburg M, Richette P, Butte AJ, Mariotti-Ferrandiz E, Berenbaum F, Sokol H, Sellam J. PMID: 37105396.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Nucleic acid biomarkers of immune response and cell and tissue damage in children with COVID-19 and MIS-C. Cell Rep Med. 2023 06 20; 4(6):101034.
Loy CJ, Sotomayor-Gonzalez A, Servellita V, Nguyen J, Lenz J, Bhattacharya S, Williams ME, Cheng AP, Bliss A, Saldhi P, Brazer N, Streithorst J, Suslovic W, Hsieh CJ, Bahar B, Wood N, Foresythe A, Gliwa A, Bhakta K, Perez MA, Hussaini L, Anderson EJ, Chahroudi A, Delaney M, Butte AJ, DeBiasi RL, Rostad CA, De Vlaminck I, Chiu CY. PMID: 37279751; PMCID: PMC10121104.
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PubMed Mentions:
6 Fields:
Translation:
Humans
-
Contextualising adverse events of special interest to characterise the baseline incidence rates in 24 million patients with COVID-19 across 26 databases: a multinational retrospective cohort study. EClinicalMedicine. 2023 Apr; 58:101932.
Voss EA, Shoaibi A, Yin Hui Lai L, Blacketer C, Alshammari T, Makadia R, Haynes K, Sena AG, Rao G, van Sandijk S, Fraboulet C, Boyer L, Le Carrour T, Horban S, Morales DR, Martínez Roldán J, Ramírez-Anguita JM, Mayer MA, de Wilde M, John LH, Duarte-Salles T, Roel E, Pistillo A, Kolde R, Maljkovic F, Denaxas S, Papez V, Kahn MG, Natarajan K, Reich C, Secora A, Minty EP, Shah NH, Posada JD, Garcia Morales MT, Bosca D, Cadenas Juanino H, Diaz Holgado A, Pedrera Jiménez M, Serrano Balazote P, García Barrio N, Sen S, Üresin AY, Erdogan B, Belmans L, Byttebier G, Malbrain MLNG, Dedman DJ, Cuccu Z, Vashisht R, Butte AJ, Patel A, Dahm L, Han C, Bu F, Arshad F, Ostropolets A, Nyberg F, Hripcsak G, Suchard MA, Prieto-Alhambra D, Rijnbeek PR, Schuemie MJ, Ryan PB. PMID: 37034358; PMCID: PMC10072853.
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PubMed Mentions:
3
-
Defining incidence and complications of fibrolamellar liver cancer through tiered computational analysis of clinical data. NPJ Precis Oncol. 2023 Mar 23; 7(1):29.
Zack T, Losert KP, Maisel SM, Wild J, Yaqubie A, Herman M, Knox JJ, Mayer RJ, Venook AP, Butte A, O'Neill AF, Abou-Alfa GK, Gordan JD. PMID: 36959495; PMCID: PMC10034241.
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PubMed Mentions:
4
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Creation of an ustekinumab external control arm for Crohn's disease using electronic health records data: A pilot study. PLoS One. 2023; 18(3):e0282267.
Rudrapatna VA, Cheng YW, Feuille C, Mosenia A, Shih J, Shi Y, Roberson O, Rubin B, Butte AJ, Mahadevan U, Skomrock N, Erondu N, Chehoud C, Rahim S, Apfel D, Curran M, Khan NS, O'Brien C, Terry N, Martini BD. PMID: 36862717; PMCID: PMC9980824.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Data Sharing Enters a New Era. Ann Intern Med. 2023 03; 176(3):400-401.
Bauchner H, McDermott MM, Butte AJ. PMID: 36848652.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Real-world utilization of SARS-CoV-2 serological testing in RNA positive patients across the United States. PLoS One. 2023; 18(2):e0281365.
Rodriguez-Watson CV, Sheils NE, Louder AM, Eldridge EH, Lin ND, Pollock BD, Gatz JL, Grannis SJ, Vashisht R, Ghauri K, Valo G, Chakravarty AG, Lasky T, Jung M, Lovell SL, Major JM, Kabelac C, Knepper C, Leonard S, Embi PJ, Jenkinson WG, Klesh R, Garner OB, Patel A, Dahm L, Barin A, Cooper DM, Andriola T, Byington CL, Crews BO, Butte AJ, Allen J. PMID: 36763574; PMCID: PMC9916659.
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PubMed Mentions: Fields:
Translation:
HumansCellsPHPublic Health
-
Real-world performance of SARS-Cov-2 serology tests in the United States, 2020. PLoS One. 2023; 18(2):e0279956.
Rodriguez-Watson CV, Louder AM, Kabelac C, Frederick CM, Sheils NE, Eldridge EH, Lin ND, Pollock BD, Gatz JL, Grannis SJ, Vashisht R, Ghauri K, Knepper C, Leonard S, Embi PJ, Jenkinson G, Klesh R, Garner OB, Patel A, Dahm L, Barin A, Cooper DM, Andriola T, Byington CL, Crews BO, Butte AJ, Allen J. PMID: 36735683; PMCID: PMC9897562.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Identification of Symptom Phenotypes of Hand Osteoarthritis Using Hierarchical Clustering: Results From the DIGICOD Cohort. Arthritis Care Res (Hoboken). 2023 07; 75(7):1494-1502.
Binvignat M, Pires G, Tchitchek N, Costantino F, Courties A, Klatzmann D, Butte AJ, Combe B, Dougados M, Richette P, Mariotti-Ferrandiz E, Berenbaum F, Sellam J. PMID: 36263851.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
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Electrocardiogram Detection of Pulmonary Hypertension Using Deep Learning. J Card Fail. 2023 07; 29(7):1017-1028.
Aras MA, Abreau S, Mills H, Radhakrishnan L, Klein L, Mantri N, Rubin B, Barrios J, Chehoud C, Kogan E, Gitton X, Nnewihe A, Quinn D, Bridges C, Butte AJ, Olgin JE, Tison GH. PMID: 36706977; PMCID: PMC10363571.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
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Advancing evidence-based treatment of infectious diseases in children with real-world data: Opportunities and challenges. Front Pharmacol. 2022; 13:1054688.
Radtke KK, Butte AJ. PMID: 36712690; PMCID: PMC9877410.
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PubMed Mentions:
-
View in:
PubMed Mentions:
3
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Paging the Clinical Informatics Community: Respond STAT to Dobbs v. Jackson's Women's Health Organization. Appl Clin Inform. 2023 01; 14(1):164-171.
Arvisais-Anhalt S, Ravi A, Weia B, Aarts J, Ahmad HB, Araj E, Bauml JA, Benham-Hutchins M, Boyd AD, Brecht-Doscher A, Butler-Henderson K, Butte AJ, Cardilo AB, Chilukuri N, Cho MK, Cohen JK, Craven CK, Crusco S, Dadabhoy F, Dash D, DeBolt C, Elkin PL, Fayanju OA, Fochtmann LJ, Graham JV, Hanna JJ, Hersh W, Hofford MR, Hron JD, Huang SS, Jackson BR, Kaplan B, Kelly W, Ko K, Koppel R, Kurapati N, Labbad G, Lee JJ, Lehmann CU, Leitner S, Liao ZC, Medford RJ, Melnick ER, Muniyappa AN, Murray SG, Neinstein AB, Nichols-Johnson V, Novak LL, Ogan WS, Ozeran L, Pageler NM, Pandita D, Perumbeti A, Petersen C, Pierce L, Puttagunta R, Ramaswamy P, Rogers KM, Rosenbloom ST, Ryan A, Saleh S, Sarabu C, Schreiber R, Shaw KA, Sim I, Sirintrapun SJ, Solomonides A, Spector JD, Starren JB, Stoffel M, Subbian V, Swanson K, Tomes A, Trang K, Unertl KM, Weon JL, Whooley MA, Wiley K, Williamson DFK, Winkelstein P, Wong J, Xie J, Yarahuan JKW, Yung N, Zera C, Ratanawongsa N, Sadasivaiah S. PMID: 36535703; PMCID: PMC9977563.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Predictive Models for Length of Stay and Discharge Disposition in Elective Spine Surgery: Development, Validation, and Comparison to the ACS NSQIP Risk Calculator. Spine (Phila Pa 1976). 2023 Jan 01; 48(1):E1-E13.
Arora A, Lituiev D, Jain D, Hadley D, Butte AJ, Berven S, Peterson TA. PMID: 36398784; PMCID: PMC9772082.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
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Early immune markers of clinical, virological, and immunological outcomes in patients with COVID-19: a multi-omics study. Elife. 2022 10 14; 11.
Hu Z, van der Ploeg K, Chakraborty S, Arunachalam PS, Mori DAM, Jacobson KB, Bonilla H, Parsonnet J, Andrews JR, Holubar M, Subramanian A, Khosla C, Maldonado Y, Hedlin H, de la Parte L, Press K, Ty M, Tan GS, Blish C, Takahashi S, Rodriguez-Barraquer I, Greenhouse B, Butte AJ, Singh U, Pulendran B, Wang TT, Jagannathan P. PMID: 36239699; PMCID: PMC9566856.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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From Genes to Geography, from Cells to Community, from Biomolecules to Behaviors: The Importance of Social Determinants of Health. Biomolecules. 2022 10 09; 12(10).
Davidson J, Vashisht R, Butte AJ. PMID: 36291658; PMCID: PMC9599320.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
Predictability and stability testing to assess clinical decision instrument performance for children after blunt torso trauma. PLOS Digit Health. 2022 Aug; 1(8):e0000076.
Kornblith AE, Singh C, Devlin G, Addo N, Streck CJ, Holmes JF, Kuppermann N, Grupp-Phelan J, Fineman J, Butte AJ, Yu B. PMID: 36812570; PMCID: PMC9931266.
View in:
PubMed Mentions:
1
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Machine Learning Methods in Health Economics and Outcomes Research-The PALISADE Checklist: A Good Practices Report of an ISPOR Task Force. Value Health. 2022 07; 25(7):1063-1080.
Padula WV, Kreif N, Vanness DJ, Adamson B, Rueda JD, Felizzi F, Jonsson P, IJzerman MJ, Butte A, Crown W. PMID: 35779937.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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The Promise of Digital Health: Then, Now, and the Future. NAM Perspect. 2022; 2022.
Abernethy A, Adams L, Barrett M, Bechtel C, Brennan P, Butte A, Faulkner J, Fontaine E, Friedhoff S, Halamka J, Howell M, Johnson K, Long P, McGraw D, Miller R, Lee P, Perlin J, Rucker D, Sandy L, Savage L, Stump L, Tang P, Topol E, Tuckson R, Valdes K. PMID: 36177208; PMCID: PMC9499383.
View in:
PubMed Mentions:
74
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Trans-channel fluorescence learning improves high-content screening for Alzheimer's disease therapeutics. Nat Mach Intell. 2022 Jun; 4(6):583-595.
Wong DR, Conrad J, Johnson N, Ayers J, Laeremans A, Lee JC, Lee J, Prusiner SB, Bandyopadhyay S, Butte AJ, Paras NA, Keiser MJ. PMID: 36276634; PMCID: PMC9585544.
View in:
PubMed Mentions:
5
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Deep learning from multiple experts improves identification of amyloid neuropathologies. Acta Neuropathol Commun. 2022 04 28; 10(1):66.
Wong DR, Tang Z, Mew NC, Das S, Athey J, McAleese KE, Kofler JK, Flanagan ME, Borys E, White CL, Butte AJ, Dugger BN, Keiser MJ. PMID: 35484610; PMCID: PMC9052651.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Use of machine learning in osteoarthritis research: a systematic literature review. RMD Open. 2022 03; 8(1).
Binvignat M, Pedoia V, Butte AJ, Louati K, Klatzmann D, Berenbaum F, Mariotti-Ferrandiz E, Sellam J. PMID: 35296530; PMCID: PMC8928401.
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PubMed Mentions:
20 Translation:
Humans
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Individualized Constellation of Killer Cell Immunoglobulin-Like Receptors and Cognate HLA Class I Ligands that Controls Natural Killer Cell Antiviral Immunity Predisposes COVID-19. Front Genet. 2022; 13:845474.
Maruthamuthu S, Rajalingam K, Kaur N, Morvan MG, Soto J, Lee N, Kong D, Hu Z, Reyes K, Ng D, Butte AJ, Chiu C, Rajalingam R. PMID: 35273641; PMCID: PMC8902362.
View in:
PubMed Mentions:
12
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Early immune responses have long-term associations with clinical, virologic, and immunologic outcomes in patients with COVID-19. Res Sq. 2022 Feb 02.
Hu Z, van der Ploeg K, Chakraborty S, Arunachalam P, Mori D, Jacobson K, Bonilla H, Parsonnet J, Andrews J, Hedlin H, de la Parte L, Dantzler K, Ty M, Tan G, Blish C, Takahashi S, Rodriguez-Barraquer I, Greenhouse B, Butte A, Singh U, Pulendran B, Wang T, Jagannathan P. PMID: 35132407; PMCID: PMC8820672.
View in:
PubMed Mentions:
1
-
Embedding electronic health records onto a knowledge network recognizes prodromal features of multiple sclerosis and predicts diagnosis. J Am Med Inform Assoc. 2022 01 29; 29(3):424-434.
Nelson CA, Bove R, Butte AJ, Baranzini SE. PMID: 34915552; PMCID: PMC8800523.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
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Open challenges in developing digital therapeutics in the United States. PLOS Digit Health. 2022 Jan; 1(1):e0000008.
Miao BY, Arneson D, Wang M, Butte AJ. PMID: 36812515; PMCID: PMC9931293.
View in:
PubMed Mentions:
8
-
Systematic identification of ACE2 expression modulators reveals cardiomyopathy as a risk factor for mortality in COVID-19 patients. Genome Biol. 2022 01 10; 23(1):15.
Kaur N, Oskotsky B, Butte AJ, Hu Z. PMID: 35012625; PMCID: PMC8743438.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
View in:
PubMed Mentions:
22 Fields:
Translation:
Humans
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Application of Machine Learning for Cytometry Data. Front Immunol. 2021; 12:787574.
Hu Z, Bhattacharya S, Butte AJ. PMID: 35046945; PMCID: PMC8761933.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansAnimals
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Heterogeneity of Diabetes: β-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases. Diabetes Care. 2022 01 01; 45(1):3-22.
Cefalu WT, Andersen DK, Arreaza-Rubín G, Pin CL, Sato S, Verchere CB, Woo M, Rosenblum ND, Symposium planning committee, moderators, and speakers. PMID: 34782355; PMCID: PMC8753760.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Opal: an implementation science tool for machine learning clinical decision support in anesthesia. J Clin Monit Comput. 2022 10; 36(5):1367-1377.
Bishara A, Wong A, Wang L, Chopra M, Fan W, Lin A, Fong N, Palacharla A, Spinner J, Armstrong R, Pletcher MJ, Lituiev D, Hadley D, Butte A. PMID: 34837585; PMCID: PMC9275816.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Heterogeneity of Diabetes: β-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases. Diabetes. 2021 11 15.
Cefalu WT, Andersen DK, Arreaza-Rubín G, Pin CL, Sato S, Verchere CB, Woo M, Rosenblum ND, symposium planning committee, moderators, and speakers. PMID: 34782351; PMCID: PMC8763877.
View in:
PubMed Mentions:
4 Fields:
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Heterogeneity of Diabetes: β-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases. Can J Diabetes. 2021 Dec; 45(8):697-713.
Cefalu WT, Andersen DK, Arreaza-Rubín G, Pin CL, Sato S, Verchere CB, Woo M, Rosenblum ND, symposium planning committee, moderators, and speakers. PMID: 34794897.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Heterogeneity of Diabetes: β-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases. Diabetes. 2021 11 13.
Cefalu WT, Andersen DK, Arreaza-Rubín G, Pin CL, Sato S, Verchere CB, Woo M, Rosenblum ND, Symposium planning committee, moderators, and speakers:, Rosenblum N, Cefalu W, Andersen DK, Arreaza-Rubín G, Dhara C, James SP, Makarchuk MJ, Pin CL, Sato S, Verchere B, Woo M, Powers A, Estall J, Hoesli C, Millman J, Linnemann A, Johnson J, Pin CL, Hawkins M, Woo M, Gloyn A, Cefalu W, Rosenblum N, Huising MO, Benninger RKP, Almaça J, Hull-Meichle RL, MacDonald P, Lynn F, Melero-Martin J, Yoshihara E, Stabler C, Sander M, Evans-Molina C, Engin F, Thompson P, Shalev A, Redondo MJ, Nadeau K, Bellin M, Udler MS, Dennis J, Dash S, Zhou W, Snyder M, Booth G, Butte A, Florez J. PMID: 34957490.
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PubMed Mentions:
3 Fields:
-
Development and Validation of a Deep Learning Strategy for Automated View Classification of Pediatric Focused Assessment With Sonography for Trauma. J Ultrasound Med. 2022 Aug; 41(8):1915-1924.
Kornblith AE, Addo N, Dong R, Rogers R, Grupp-Phelan J, Butte A, Gupta P, Callcut RA, Arnaout R. PMID: 34741469; PMCID: PMC9072593.
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PubMed Mentions:
4 Fields:
Translation:
Humans
-
Case-control study of the association of chronic acid suppression and social determinants of health with COVID-19 infection. Sci Rep. 2021 10 25; 11(1):20987.
Zhang B, Silverman AL, Bangaru S, Arneson D, Dasharathy S, Nguyen N, Rodden D, Shih J, Butte AJ, El-Nachef WN, Boland BS, Rudrapatna VA. PMID: 34697319; PMCID: PMC8545937.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Five-year pediatric use of a digital wearable fitness device: lessons from a pilot case study. JAMIA Open. 2021 Jul; 4(3):ooab054.
Butte KD, Bahmani A, Butte AJ, Li X, Snyder MP. PMID: 34350390; PMCID: PMC8327370.
View in:
PubMed Mentions:
2
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Assessing Clinical Outcomes in a Data-Rich World-A Reality Check on Real-World Data. JAMA Netw Open. 2021 07 01; 4(7):e2117826.
Hong JC, Butte AJ. PMID: 34309673.
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PubMed Mentions:
2 Fields:
-
Big Data in Nephrology. Nat Rev Nephrol. 2021 Oct; 17(10):676-687.
Kaur N, Bhattacharya S, Butte AJ. PMID: 34194006.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Impact of Different Approaches to Preparing Notes for Analysis With Natural Language Processing on the Performance of Prediction Models in Intensive Care. Crit Care Explor. 2021 Jun; 3(6):e0450.
Mahendra M, Luo Y, Mills H, Schenk G, Butte AJ, Dudley RA. PMID: 34136824; PMCID: PMC8202578.
View in:
PubMed Mentions:
4
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Rethinking PICO in the Machine Learning Era: ML-PICO. Appl Clin Inform. 2021 03; 12(2):407-416.
Liu X, Anstey J, Li R, Sarabu C, Sono R, Butte AJ. PMID: 34010977; PMCID: PMC8133838.
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PubMed Mentions:
4 Fields:
-
Utility of routinely collected electronic health records data to support effectiveness evaluations in inflammatory bowel disease: a pilot study of tofacitinib. BMJ Health Care Inform. 2021 May; 28(1).
Rudrapatna VA, Glicksberg BS, Butte AJ. PMID: 34011632; PMCID: PMC8141436.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
Opportunities and Challenges in Democratizing Immunology Datasets. Front Immunol. 2021; 12:647536.
Bhattacharya S, Hu Z, Butte AJ. PMID: 33936065; PMCID: PMC8086961.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Use of electronic health records to support a public health response to the COVID-19 pandemic in the United States: a perspective from 15 academic medical centers. J Am Med Inform Assoc. 2021 02 15; 28(2):393-401.
Madhavan S, Bastarache L, Brown JS, Butte AJ, Dorr DA, Embi PJ, Friedman CP, Johnson KB, Moore JH, Kohane IS, Payne PRO, Tenenbaum JD, Weiner MG, Wilcox AB, Ohno-Machado L. PMID: 33260207; PMCID: PMC7665546.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansPHPublic Health
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Algorithmic Stewardship in Health Care-Reply. JAMA. 2021 02 09; 325(6):588-589.
Eaneff S, Obermeyer Z, Butte AJ. PMID: 33560318.
View in:
PubMed Mentions: Fields:
-
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Quantifying Variation in Treatment Utilization for Type 2 Diabetes Across Five Major University of California Health Systems. Diabetes Care. 2021 04; 44(4):908-914.
Peterson TA, Fontil V, Koliwad SK, Patel A, Butte AJ. PMID: 33531419; PMCID: PMC7985428.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Age- and Sex-Associated Variations in the Sensitivity of Serological Tests Among Individuals Infected With SARS-CoV-2. JAMA Netw Open. 2021 02 01; 4(2):e210337.
Vashisht R, Patel A, Crews BO, Garner OB, Dahm L, Wilson C, Butte AJ. PMID: 33576815; PMCID: PMC7881354.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Knowledge Network Embedding of Transcriptomic Data from Spaceflown Mice Uncovers Signs and Symptoms Associated with Terrestrial Diseases. Life (Basel). 2021 Jan 12; 11(1).
Nelson CA, Acuna AU, Paul AM, Scott RT, Butte AJ, Cekanaviciute E, Baranzini SE, Costes SV. PMID: 33445483; PMCID: PMC7828077.
View in:
PubMed Mentions:
8
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Trials and Tribulations-11 Reasons Why We Need to Promote Clinical Trials Data Sharing. JAMA Netw Open. 2021 01 04; 4(1):e2035043.
Butte AJ. PMID: 33507252.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Characteristics and challenges of the clinical pipeline of digital therapeutics. NPJ Digit Med. 2020 Dec 11; 3(1):159.
Patel NA, Butte AJ. PMID: 33311567; PMCID: PMC7733514.
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PubMed Mentions:
52
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Identification of antiviral antihistamines for COVID-19 repurposing. Biochem Biophys Res Commun. 2021 01 29; 538:173-179.
Reznikov LR, Norris MH, Vashisht R, Bluhm AP, Li D, Liao YJ, Brown A, Butte AJ, Ostrov DA. PMID: 33309272; PMCID: PMC7713548.
View in:
PubMed Mentions:
46 Fields:
Translation:
HumansAnimalsCells
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Human splice factors contribute to latent HIV infection in primary cell models and blood CD4+ T cells from ART-treated individuals. PLoS Pathog. 2020 11; 16(11):e1009060.
Moron-Lopez S, Telwatte S, Sarabia I, Battivelli E, Montano M, Macedo AB, Aran D, Butte AJ, Jones RB, Bosque A, Verdin E, Greene WC, Wong JK, Yukl SA. PMID: 33253324; PMCID: PMC7728277.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCells
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CovidCounties is an interactive real time tracker of the COVID19 pandemic at the level of US counties. Sci Data. 2020 11 16; 7(1):405.
Arneson D, Elliott M, Mosenia A, Oskotsky B, Solodar S, Vashisht R, Zack T, Bleicher P, Butte AJ, Rudrapatna VA. PMID: 33199721; PMCID: PMC7669883.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCellsPHPublic Health
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The Case for Algorithmic Stewardship for Artificial Intelligence and Machine Learning Technologies. JAMA. 2020 Oct 13; 324(14):1397-1398.
Eaneff S, Obermeyer Z, Butte AJ. PMID: 32926087.
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PubMed Mentions:
34 Fields:
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Minimum information about clinical artificial intelligence modeling: the MI-CLAIM checklist. Nat Med. 2020 09; 26(9):1320-1324.
Norgeot B, Quer G, Beaulieu-Jones BK, Torkamani A, Dias R, Gianfrancesco M, Arnaout R, Kohane IS, Saria S, Topol E, Obermeyer Z, Yu B, Butte AJ. PMID: 32908275; PMCID: PMC7538196.
View in:
PubMed Mentions:
171 Fields:
Translation:
Humans
-
A robust and interpretable end-to-end deep learning model for cytometry data. Proc Natl Acad Sci U S A. 2020 09 01; 117(35):21373-21380.
Hu Z, Tang A, Singh J, Bhattacharya S, Butte AJ. PMID: 32801215; PMCID: PMC7474669.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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CovidCounties - an interactive, real-time tracker of the COVID-19 pandemic at the level of US counties. medRxiv. 2020 May 02.
Arneson D, Elliott M, Mosenia A, Oskotsky B, Vashisht R, Zack T, Bleicher P, Butte AJ, Rudrapatna VA. PMID: 32511606; PMCID: PMC7276033.
View in:
PubMed Mentions:
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Protected Health Information filter (Philter): accurately and securely de-identifying free-text clinical notes. NPJ Digit Med. 2020; 3:57.
Norgeot B, Muenzen K, Peterson TA, Fan X, Glicksberg BS, Schenk G, Rutenberg E, Oskotsky B, Sirota M, Yazdany J, Schmajuk G, Ludwig D, Goldstein T, Butte AJ. PMID: 32337372; PMCID: PMC7156708.
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PubMed Mentions:
35
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Predicting Inpatient Medication Orders From Electronic Health Record Data. Clin Pharmacol Ther. 2020 07; 108(1):145-154.
Rough K, Dai AM, Zhang K, Xue Y, Vardoulakis LM, Cui C, Butte AJ, Howell MD, Rajkomar A. PMID: 32141068; PMCID: PMC7325318.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
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Meta-Analysis of Vaginal Microbiome Data Provides New Insights Into Preterm Birth. Front Microbiol. 2020; 11:476.
Kosti I, Lyalina S, Pollard KS, Butte AJ, Sirota M. PMID: 32322240; PMCID: PMC7156768.
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PubMed Mentions:
33
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Time for NIH to lead on data sharing. Science. 2020 03 20; 367(6484):1308-1309.
Sim I, Stebbins M, Bierer BE, Butte AJ, Drazen J, Dzau V, Hernandez AF, Krumholz HM, Lo B, Munos B, Perakslis E, Rockhold F, Ross JS, Terry SF, Yamamoto KR, Zarin DA, Li R. PMID: 32193313.
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PubMed Mentions:
25 Fields:
-
Accuracy of medical billing data against the electronic health record in the measurement of colorectal cancer screening rates. BMJ Open Qual. 2020 03; 9(1).
Rudrapatna VA, Glicksberg BS, Avila P, Harding-Theobald E, Wang C, Butte AJ. PMID: 32209595; PMCID: PMC7103821.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansPHPublic Health
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Recent Advances in Systems and Network Medicine: Meeting Report from the First International Conference in Systems and Network Medicine. Syst Med (New Rochelle). 2020; 3(1):22-35.
Kurnat-Thoma E, Baranova A, Baird P, Brodsky E, Butte AJ, Cheema AK, Cheng F, Dutta S, Grant C, Giordano J, Maitland-van der Zee AH, Fridsma DB, Jarrin R, Kann MG, Keeney J, Loscalzo J, Madhavan G, Maron BA, McBride DK, McKean M, Mun SK, Palmer JC, Patel B, Parakh K, Pariser AR, Pristipino C, Radstake TRDJ, Rajasimha HK, Rouse WB, Rozman D, Saleh A, Schmidt HHHW, Schultz N, Sethi T, Silverman EK, Skopac J, Svab I, Trujillo S, Valentine JE, Verma D, West BJ, Vasudevan S. PMID: 32226924; PMCID: PMC7099876.
View in:
PubMed Mentions:
7
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Explanatory Model of Dry Eye Disease Using Health and Nutrition Examinations: Machine Learning and Network-Based Factor Analysis From a National Survey. JMIR Med Inform. 2020 Feb 20; 8(2):e16153.
Nam SM, Peterson TA, Butte AJ, Seo KY, Han HW. PMID: 32130150; PMCID: PMC7059080.
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PubMed Mentions:
6
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Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis. Commun Biol. 2020 02 05; 3(1):56.
Carlevaro-Fita J, Lanzós A, Feuerbach L, Hong C, Mas-Ponte D, Pedersen JS, PCAWG Drivers and Functional Interpretation Group, Johnson R, PCAWG Consortium. PMID: 32024996; PMCID: PMC7002399.
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PubMed Mentions:
104 Translation:
HumansAnimals
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Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig. Nat Commun. 2020 02 05; 11(1):731.
Rubanova Y, Shi R, Harrigan CF, Li R, Wintersinger J, Sahin N, Deshwar AG, PCAWG Evolution and Heterogeneity Working Group, Morris QD, PCAWG Consortium. PMID: 32024834; PMCID: PMC7002414.
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PubMed Mentions:
23 Fields:
Translation:
Humans
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Genomic footprints of activated telomere maintenance mechanisms in cancer. Nat Commun. 2020 02 05; 11(1):733.
Sieverling L, Hong C, Koser SD, Ginsbach P, Kleinheinz K, Hutter B, Braun DM, Cortés-Ciriano I, Xi R, Kabbe R, Park PJ, Eils R, Schlesner M, PCAWG-Structural Variation Working Group, Brors B, Rippe K, Jones DTW, Feuerbach L, PCAWG Consortium. PMID: 32024817; PMCID: PMC7002710.
View in:
PubMed Mentions:
67 Fields:
Translation:
HumansCells
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Combined burden and functional impact tests for cancer driver discovery using DriverPower. Nat Commun. 2020 02 05; 11(1):734.
Shuai S, PCAWG Drivers and Functional Interpretation Working Group, Gallinger S, Stein LD, PCAWG Consortium. PMID: 32024818; PMCID: PMC7002750.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Inferring structural variant cancer cell fraction. Nat Commun. 2020 02 05; 11(1):730.
Cmero M, Yuan K, Ong CS, Schröder J, PCAWG Evolution and Heterogeneity Working Group, Corcoran NM, Papenfuss T, Hovens CM, Markowetz F, Macintyre G, PCAWG Consortium. PMID: 32024845; PMCID: PMC7002525.
View in:
PubMed Mentions:
24 Fields:
Translation:
Humans
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A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns. Nat Commun. 2020 02 05; 11(1):728.
Jiao W, Atwal G, Polak P, Karlic R, Cuppen E, PCAWG Tumor Subtypes and Clinical Translation Working Group, Danyi A, de Ridder J, van Herpen C, Lolkema MP, Steeghs N, Getz G, Morris QD, Stein LD, PCAWG Consortium. PMID: 32024849; PMCID: PMC7002586.
View in:
PubMed Mentions:
80 Fields:
Translation:
Humans
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Integrative pathway enrichment analysis of multivariate omics data. Nat Commun. 2020 02 05; 11(1):735.
Paczkowska M, Barenboim J, Sintupisut N, Fox NS, Zhu H, Abd-Rabbo D, Mee MW, Boutros PC, PCAWG Drivers and Functional Interpretation Working Group, Reimand J, PCAWG Consortium. PMID: 32024846; PMCID: PMC7002665.
View in:
PubMed Mentions:
82 Fields:
Translation:
HumansCells
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High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations. Nat Commun. 2020 02 05; 11(1):736.
Zhang Y, Chen F, Fonseca NA, He Y, Fujita M, Nakagawa H, Zhang Z, Brazma A, PCAWG Transcriptome Working Group, PCAWG Structural Variation Working Group, Creighton CJ, PCAWG Consortium. PMID: 32024823; PMCID: PMC7002524.
View in:
PubMed Mentions:
43 Fields:
Translation:
HumansCells
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Divergent mutational processes distinguish hypoxic and normoxic tumours. Nat Commun. 2020 02 05; 11(1):737.
Bhandari V, Li CH, Bristow RG, Boutros PC, PCAWG Consortium. PMID: 32024819; PMCID: PMC7002770.
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PubMed Mentions:
62 Fields:
Translation:
Humans
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Pathway and network analysis of more than 2500 whole cancer genomes. Nat Commun. 2020 02 05; 11(1):729.
Reyna MA, Haan D, Paczkowska M, Verbeke LPC, Vazquez M, Kahraman A, Pulido-Tamayo S, Barenboim J, Wadi L, Dhingra P, Shrestha R, Getz G, Lawrence MS, Pedersen JS, Rubin MA, Wheeler DA, Brunak S, Izarzugaza JMG, Khurana E, Marchal K, von Mering C, Sahinalp SC, Valencia A, PCAWG Drivers and Functional Interpretation Working Group, Reimand J, Stuart JM, Raphael BJ, PCAWG Consortium. PMID: 32024854; PMCID: PMC7002574.
View in:
PubMed Mentions:
49 Fields:
Translation:
HumansCells
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Opportunities and challenges in using real-world data for health care. J Clin Invest. 2020 02 03; 130(2):565-574.
Rudrapatna VA, Butte AJ. PMID: 32011317; PMCID: PMC6994109.
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PubMed Mentions:
64 Fields:
Translation:
Humans
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Corticosteroid use is not associated with improved outcomes in acute exacerbation of IPF. Respirology. 2020 06; 25(6):629-635.
Farrand E, Vittinghoff E, Ley B, Butte AJ, Collard HR. PMID: 31846126.
View in:
PubMed Mentions:
30 Fields:
Translation:
Humans
-
Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency. Retrovirology. 2019 11 11; 16(1):32.
Telwatte S, Morón-López S, Aran D, Kim P, Hsieh C, Joshi S, Montano M, Greene WC, Butte AJ, Wong JK, Yukl SA. PMID: 31711503; PMCID: PMC6849327.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansCells
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PatientExploreR: an extensible application for dynamic visualization of patient clinical history from electronic health records in the OMOP common data model. Bioinformatics. 2019 11 01; 35(21):4515-4518.
Glicksberg BS, Oskotsky B, Thangaraj PM, Giangreco N, Badgeley MA, Johnson KW, Datta D, Rudrapatna VA, Rappoport N, Shervey MM, Miotto R, Goldstein TC, Rutenberg E, Frazier R, Lee N, Israni S, Larsen R, Percha B, Li L, Dudley JT, Tatonetti NP, Butte AJ. PMID: 31214700; PMCID: PMC6821222.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Tracing diagnosis trajectories over millions of patients reveal an unexpected risk in schizophrenia. Sci Data. 2019 10 15; 6(1):201.
Paik H, Kan MJ, Rappoport N, Hadley D, Sirota M, Chen B, Manber U, Cho SB, Butte AJ. PMID: 31615985; PMCID: PMC6794302.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types. Nat Commun. 2019 08 08; 10(1):3574.
Yu K, Chen B, Aran D, Charalel J, Yau C, Wolf DM, van 't Veer LJ, Butte AJ, Goldstein T, Sirota M. PMID: 31395879; PMCID: PMC6687785.
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PubMed Mentions:
79 Fields:
Translation:
HumansCells
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Integrating biomedical research and electronic health records to create knowledge-based biologically meaningful machine-readable embeddings. Nat Commun. 2019 07 10; 10(1):3045.
Nelson CA, Butte AJ, Baranzini SE. PMID: 31292438; PMCID: PMC6620318.
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PubMed Mentions:
42 Fields:
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A longitudinal big data approach for precision health. Nat Med. 2019 05; 25(5):792-804.
Schüssler-Fiorenza Rose SM, Contrepois K, Moneghetti KJ, Zhou W, Mishra T, Mataraso S, Dagan-Rosenfeld O, Ganz AB, Dunn J, Hornburg D, Rego S, Perelman D, Ahadi S, Sailani MR, Zhou Y, Leopold SR, Chen J, Ashland M, Christle JW, Avina M, Limcaoco P, Ruiz C, Tan M, Butte AJ, Weinstock GM, Slavich GM, Sodergren E, McLaughlin TL, Haddad F, Snyder MP. PMID: 31068711; PMCID: PMC6713274.
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PubMed Mentions:
180 Fields:
Translation:
HumansCells
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Closing the Evidence Gap in Interstitial Lung Disease. The Promise of Real-World Data. Am J Respir Crit Care Med. 2019 05 01; 199(9):1061-1065.
Farrand E, Anstrom KJ, Bernard G, Butte AJ, Iribarren C, Ley B, Martinez FJ, Collard HR. PMID: 30452876.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Assessment of Postdonation Outcomes in US Living Kidney Donors Using Publicly Available Data Sets. JAMA Netw Open. 2019 04 05; 2(4):e191851.
Chen J, Bhattacharya S, Sirota M, Laiudompitak S, Schaefer H, Thomson E, Wiser J, Sarwal MM, Butte AJ. PMID: 30977847; PMCID: PMC6481454.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
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Robust prediction of clinical outcomes using cytometry data. Bioinformatics. 2019 04 01; 35(7):1197-1203.
Hu Z, Glicksberg BS, Butte AJ. PMID: 30169745; PMCID: PMC6449751.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
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Assessment of a Deep Learning Model Based on Electronic Health Record Data to Forecast Clinical Outcomes in Patients With Rheumatoid Arthritis. JAMA Netw Open. 2019 03 01; 2(3):e190606.
Norgeot B, Glicksberg BS, Trupin L, Lituiev D, Gianfrancesco M, Oskotsky B, Schmajuk G, Yazdany J, Butte AJ. PMID: 30874779; PMCID: PMC6484652.
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PubMed Mentions:
86 Fields:
Translation:
Humans
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A pilot study showing a stronger H1N1 influenza vaccination response during pregnancy in women who subsequently deliver preterm. J Reprod Immunol. 2019 04; 132:16-20.
Andorf S, Bhattacharya S, Gaudilliere B, Shaw GM, Stevenson DK, Butte AJ, Sirota M. PMID: 30852461; PMCID: PMC6456418.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCellsPHPublic Health
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Prototype of running clinical trials in an untrustworthy environment using blockchain. Nat Commun. 2019 02 22; 10(1):917.
Wong DR, Bhattacharya S, Butte AJ. PMID: 30796226; PMCID: PMC6384889.
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PubMed Mentions:
34 Fields:
Translation:
Humans
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Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage. Nat Immunol. 2019 02; 20(2):163-172.
Aran D, Looney AP, Liu L, Wu E, Fong V, Hsu A, Chak S, Naikawadi RP, Wolters PJ, Abate AR, Butte AJ, Bhattacharya M. PMID: 30643263; PMCID: PMC6340744.
View in:
PubMed Mentions:
1783 Fields:
Translation:
HumansAnimalsCells
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ROMOP: a light-weight R package for interfacing with OMOP-formatted electronic health record data. JAMIA Open. 2019 Apr; 2(1):10-14.
Glicksberg BS, Oskotsky B, Giangreco N, Thangaraj PM, Rudrapatna V, Datta D, Frazier R, Lee N, Larsen R, Tatonetti NP, Butte AJ. PMID: 31633087; PMCID: PMC6800657.
View in:
PubMed Mentions:
6
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A call for deep-learning healthcare. Nat Med. 2019 Jan; 25(1):14-15.
Norgeot B, Glicksberg BS, Butte AJ. PMID: 30617337.
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PubMed Mentions:
68 Fields:
Translation:
Humans
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Better medicine through machine learning: What's real, and what's artificial? PLoS Med. 2018 12; 15(12):e1002721.
Saria S, Butte A, Sheikh A. PMID: 30596635; PMCID: PMC6312199.
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PubMed Mentions:
30 Fields:
Translation:
Humans
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Author Correction: Enabling precision medicine in neonatology, an integrated repository for preterm birth research. Sci Data. 2018 12 18; 5(1):3.
Sirota M, Thomas CG, Liu R, Zuhl M, Banerjee P, Wong RJ, Quaintance CC, Leite R, Chubiz J, Anderson R, Chappell J, Kim M, Grobman W, Zhang G, Rokas A, Muglia LJ, Ober C, England SK, Macones G, Driscoll D, Parry S, Shaw GM, Stevenson DK, Simpson JL, Thomson E, Butte AJ, March of Dimes Prematurity Research Centers. PMID: 30563979; PMCID: PMC6309114.
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PubMed Mentions: Fields:
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Personal Mutanomes Meet Modern Oncology Drug Discovery and Precision Health. Pharmacol Rev. 2019 01; 71(1):1-19.
Cheng F, Liang H, Butte AJ, Eng C, Nussinov R. PMID: 30545954; PMCID: PMC6294046.
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PubMed Mentions:
30 Fields:
Translation:
Humans
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Open data informatics and data repurposing for IBD. Nat Rev Gastroenterol Hepatol. 2018 12; 15(12):715-716.
Rudrapatna VA, Butte AJ. PMID: 30061595; PMCID: PMC6687058.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
The 10,000 Immunomes Project: Building a Resource for Human Immunology. Cell Rep. 2018 Nov 13; 25(7):1995.
Zalocusky KA, Kan MJ, Hu Z, Dunn P, Thomson E, Wiser J, Bhattacharya S, Butte AJ. PMID: 30428364; PMCID: PMC6362995.
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PubMed Mentions:
8 Fields:
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Enabling precision medicine in neonatology, an integrated repository for preterm birth research. Sci Data. 2018 11 06; 5:180219.
Sirota M, Thomas CG, Liu R, Zuhl M, Banerjee P, Wong RJ, Quaintance CC, Leite R, Chubiz J, Anderson R, Chappell J, Kim M, Grobman W, Zhang G, Rokas A, England SK, Parry S, Shaw GM, Simpson JL, Thomson E, Butte AJ, March of Dimes Prematurity Research Centers. PMID: 30398470; PMCID: PMC6219406.
View in:
PubMed Mentions:
10 Fields:
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Comparing Ethnicity-Specific Reference Intervals for Clinical Laboratory Tests from EHR Data. J Appl Lab Med. 2018 Nov 01; 3(3):366-377.
Rappoport N, Paik H, Oskotsky B, Tor R, Ziv E, Zaitlen N, Butte AJ. PMID: 33636914; PMCID: PMC8404742.
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PubMed Mentions:
16 Fields:
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The 10,000 Immunomes Project: Building a Resource for Human Immunology. Cell Rep. 2018 10 09; 25(2):513-522.e3.
Zalocusky KA, Kan MJ, Hu Z, Dunn P, Thomson E, Wiser J, Bhattacharya S, Butte AJ. PMID: 30304689; PMCID: PMC6263160.
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PubMed Mentions:
22 Fields:
Translation:
HumansCells
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MetaCyto: A Tool for Automated Meta-analysis of Mass and Flow Cytometry Data. Cell Rep. 2018 07 31; 24(5):1377-1388.
Hu Z, Jujjavarapu C, Hughey JJ, Andorf S, Lee HC, Gherardini PF, Spitzer MH, Thomas CG, Campbell J, Dunn P, Wiser J, Kidd BA, Dudley JT, Nolan GP, Bhattacharya S, Butte AJ. PMID: 30067990; PMCID: PMC6583920.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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Scalable and accurate deep learning with electronic health records. NPJ Digit Med. 2018; 1:18.
Rajkomar A, Oren E, Chen K, Dai AM, Hajaj N, Hardt M, Liu PJ, Liu X, Marcus J, Sun M, Sundberg P, Yee H, Zhang K, Zhang Y, Flores G, Duggan GE, Irvine J, Le Q, Litsch K, Mossin A, Tansuwan J, Wexler J, Wilson J, Ludwig D, Volchenboum SL, Chou K, Pearson M, Madabushi S, Shah NH, Butte AJ, Howell MD, Cui C, Corrado GS, Dean J. PMID: 31304302; PMCID: PMC6550175.
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PubMed Mentions:
635
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The Atacama skeleton. Genome Res. 2018 05; 28(5):607-608.
Nolan G, Butte A. PMID: 29602903; PMCID: PMC5932602.
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PubMed Mentions: Fields:
Translation:
Humans
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Whole-genome sequencing of Atacama skeleton shows novel mutations linked with dysplasia. Genome Res. 2018 04; 28(4):423-431.
Bhattacharya S, Li J, Sockell A, Kan MJ, Bava FA, Chen SC, Ávila-Arcos MC, Ji X, Smith E, Asadi NB, Lachman RS, Lam HYK, Bustamante CD, Butte AJ, Nolan GP. PMID: 29567674; PMCID: PMC5880234.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
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ImmPort, toward repurposing of open access immunological assay data for translational and clinical research. Sci Data. 2018 02 27; 5:180015.
Bhattacharya S, Dunn P, Thomas CG, Smith B, Schaefer H, Chen J, Hu Z, Zalocusky KA, Shankar RD, Shen-Orr SS, Thomson E, Wiser J, Butte AJ. PMID: 29485622; PMCID: PMC5827693.
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PubMed Mentions:
386 Fields:
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Are minor alleles more likely to be risk alleles? BMC Med Genomics. 2018 01 19; 11(1):3.
Kido T, Sikora-Wohlfeld W, Kawashima M, Kikuchi S, Kamatani N, Patwardhan A, Chen R, Sirota M, Kodama K, Hadley D, Butte AJ. PMID: 29351777; PMCID: PMC5775585.
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PubMed Mentions:
28 Fields:
Translation:
Humans
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A genome-wide association study identifies only two ancestry specific variants associated with spontaneous preterm birth. Sci Rep. 2018 01 09; 8(1):226.
Rappoport N, Toung J, Hadley D, Wong RJ, Fujioka K, Reuter J, Abbott CW, Oh S, Hu D, Eng C, Huntsman S, Bodian DL, Niederhuber JE, Hong X, Zhang G, Sikora-Wohfeld W, Gignoux CR, Wang H, Oehlert J, Jelliffe-Pawlowski LL, Gould JB, Darmstadt GL, Wang X, Bustamante CD, Snyder MP, Ziv E, Patsopoulos NA, Muglia LJ, Burchard E, Shaw GM, O'Brodovich HM, Stevenson DK, Butte AJ, Sirota M. PMID: 29317701; PMCID: PMC5760643.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Risky Business: Meeting the Structural Needs of Transdisciplinary Science. J Pediatr. 2017 12; 191:255-258.
Wise PH, Shaw GM, Druzin ML, Darmstadt GL, Quaintance C, Mäkinen E, Relman DA, Quake SR, Butte AJ, Angst MS, Muglia LJ, Macones G, Driscoll D, Ober C, Simpson JL, Katz M, Howse J, Stevenson DK. PMID: 29173314.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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xCell: digitally portraying the tissue cellular heterogeneity landscape. Genome Biol. 2017 11 15; 18(1):220.
Aran D, Hu Z, Butte AJ. PMID: 29141660; PMCID: PMC5688663.
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PubMed Mentions:
2115 Fields:
Translation:
HumansCells
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Combined inhibition of atypical PKC and histone deacetylase 1 is cooperative in basal cell carcinoma treatment. JCI Insight. 2017 11 02; 2(21).
Mirza AN, Fry MA, Urman NM, Atwood SX, Roffey J, Ott GR, Chen B, Lee A, Brown AS, Aasi SZ, Hollmig T, Ator MA, Dorsey BD, Ruggeri BR, Zificsak CA, Sirota M, Tang JY, Butte A, Epstein E, Sarin KY, Oro AE. PMID: 29093271; PMCID: PMC5752280.
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PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
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PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models. Cancer Res. 2017 11 01; 77(21):e62-e66.
Meehan TF, Conte N, Goldstein T, Inghirami G, Murakami MA, Brabetz S, Gu Z, Wiser JA, Dunn P, Begley DA, Krupke DM, Bertotti A, Bruna A, Brush MH, Byrne AT, Caldas C, Christie AL, Clark DA, Dowst H, Dry JR, Doroshow JH, Duchamp O, Evrard YA, Ferretti S, Frese KK, Goodwin NC, Greenawalt D, Haendel MA, Hermans E, Houghton PJ, Jonkers J, Kemper K, Khor TO, Lewis MT, Lloyd KCK, Mason J, Medico E, Neuhauser SB, Olson JM, Peeper DS, Rueda OM, Seong JK, Trusolino L, Vinolo E, Wechsler-Reya RJ, Weinstock DM, Welm A, Weroha SJ, Amant F, Pfister SM, Kool M, Parkinson H, Butte AJ, Bult CJ. PMID: 29092942; PMCID: PMC5738926.
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PubMed Mentions:
69 Fields:
Translation:
HumansAnimals
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Future cancer research priorities in the USA: a Lancet Oncology Commission. Lancet Oncol. 2017 11; 18(11):e653-e706.
Jaffee EM, Dang CV, Agus DB, Alexander BM, Anderson KC, Ashworth A, Barker AD, Bastani R, Bhatia S, Bluestone JA, Brawley O, Butte AJ, Coit DG, Davidson NE, Davis M, DePinho RA, Diasio RB, Draetta G, Frazier AL, Futreal A, Gambhir SS, Ganz PA, Garraway L, Gerson S, Gupta S, Heath J, Hoffman RI, Hudis C, Hughes-Halbert C, Ibrahim R, Jadvar H, Kavanagh B, Kittles R, Le QT, Lippman SM, Mankoff D, Mardis ER, Mayer DK, McMasters K, Meropol NJ, Mitchell B, Naredi P, Ornish D, Pawlik TM, Peppercorn J, Pomper MG, Raghavan D, Ritchie C, Schwarz SW, Sullivan R, Wahl R, Wolchok JD, Wong SL, Yung A. PMID: 29208398; PMCID: PMC6178838.
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PubMed Mentions:
70 Fields:
Translation:
Humans
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Comprehensive analysis of normal adjacent to tumor transcriptomes. Nat Commun. 2017 10 20; 8(1):1077.
Aran D, Camarda R, Odegaard J, Paik H, Oskotsky B, Krings G, Goga A, Sirota M, Butte AJ. PMID: 29057876; PMCID: PMC5651823.
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PubMed Mentions:
282 Fields:
Translation:
HumansCells
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Precision annotation of digital samples in NCBI's gene expression omnibus. Sci Data. 2017 09 19; 4:170125.
Hadley D, Pan J, El-Sayed O, Aljabban J, Aljabban I, Azad TD, Hadied MO, Raza S, Rayikanti BA, Chen B, Paik H, Aran D, Spatz J, Himmelstein D, Panahiazar M, Bhattacharya S, Sirota M, Musen MA, Butte AJ. PMID: 28925997; PMCID: PMC5604135.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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Big data opens a window onto wellness. Nat Biotechnol. 2017 08 08; 35(8):720-721.
Butte AJ. PMID: 28787419; PMCID: PMC5961487.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Reversal of cancer gene expression correlates with drug efficacy and reveals therapeutic targets. Nat Commun. 2017 07 12; 8:16022.
Chen B, Ma L, Paik H, Sirota M, Wei W, Chua MS, So S, Butte AJ. PMID: 28699633; PMCID: PMC5510182.
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PubMed Mentions:
95 Fields:
Translation:
HumansAnimalsCells
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Cancer Cell-Autonomous Parainflammation Mimics Immune Cell Infiltration. Cancer Res. 2017 07 15; 77(14):3740-3744.
Lasry A, Aran D, Butte AJ, Ben-Neriah Y. PMID: 28667073; PMCID: PMC5518753.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimals
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RImmPort: an R/Bioconductor package that enables ready-for-analysis immunology research data. Bioinformatics. 2017 04 01; 33(7):1101-1103.
Shankar RD, Bhattacharya S, Jujjavarapu C, Andorf S, Wiser JA, Butte AJ. PMID: 28057685; PMCID: PMC6041747.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell Division Cycle 37 Signaling. Gastroenterology. 2017 06; 152(8):2022-2036.
Chen B, Wei W, Ma L, Yang B, Gill RM, Chua MS, Butte AJ, So S. PMID: 28284560; PMCID: PMC5447464.
View in:
PubMed Mentions:
53 Fields:
Translation:
HumansCells
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Evidence for benefit of statins to modify cognitive decline and risk in Alzheimer's disease. Alzheimers Res Ther. 2017 Feb 17; 9(1):10.
Geifman N, Brinton RD, Kennedy RE, Schneider LS, Butte AJ. PMID: 28212683; PMCID: PMC5316146.
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PubMed Mentions:
81 Fields:
Translation:
Humans
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In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma. Oncotarget. 2017 Jan 17; 8(3):4079-4095.
Pessetto ZY, Chen B, Alturkmani H, Hyter S, Flynn CA, Baltezor M, Ma Y, Rosenthal HG, Neville KA, Weir SJ, Butte AJ, Godwin AK. PMID: 27863422; PMCID: PMC5354814.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Solving Immunology? Trends Immunol. 2017 02; 38(2):116-127.
Vodovotz Y, Xia A, Read EL, Bassaganya-Riera J, Hafler DA, Sontag E, Wang J, Tsang JS, Day JD, Kleinstein SH, Butte AJ, Altman MC, Hammond R, Sealfon SC. PMID: 27986392; PMCID: PMC5695553.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimals
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Integrating Clinical Phenotype and Gene Expression Data to Prioritize Novel Drug Uses. CPT Pharmacometrics Syst Pharmacol. 2016 11; 5(11):599-607.
Paik H, Chen B, Sirota M, Hadley D, Butte AJ. PMID: 27860440; PMCID: PMC5192994.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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It takes a genome to understand a village: Population scale precision medicine. Proc Natl Acad Sci U S A. 2016 11 01; 113(44):12344-12346.
Butte AJ. PMID: 27791179; PMCID: PMC5098617.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Defective Signaling in the JAK-STAT Pathway Tracks with Chronic Inflammation and Cardiovascular Risk in Aging Humans. Cell Syst. 2016 10 26; 3(4):374-384.e4.
Shen-Orr SS, Furman D, Kidd BA, Hadad F, Lovelace P, Huang YW, Rosenberg-Hasson Y, Mackey S, Grisar FA, Pickman Y, Maecker HT, Chien YH, Dekker CL, Wu JC, Butte AJ, Davis MM. PMID: 27746093; PMCID: PMC5358544.
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PubMed Mentions:
71 Fields:
Translation:
HumansCells
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Differential Phasing between Circadian Clocks in the Brain and Peripheral Organs in Humans. J Biol Rhythms. 2016 12; 31(6):588-597.
Hughey JJ, Butte AJ. PMID: 27702781; PMCID: PMC5105327.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimals
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Digitally deconvolving the tumor microenvironment. Genome Biol. 2016 08 22; 17(1):175.
Aran D, Butte AJ. PMID: 27549319; PMCID: PMC4993002.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Widespread parainflammation in human cancer. Genome Biol. 2016 07 08; 17(1):145.
Aran D, Lasry A, Zinger A, Biton M, Pikarsky E, Hellman A, Butte AJ, Ben-Neriah Y. PMID: 27386949; PMCID: PMC4937599.
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PubMed Mentions:
56 Fields:
Translation:
HumansAnimalsCells
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Identification of matrix metalloproteinase-12 as a candidate molecule for prevention and treatment of cardiometabolic disease. Mol Med. 2016 Oct; 22:487-496.
Amor M, Moreno Viedma V, Sarabi A, Grün NG, Itariu B, Leitner L, Steiner I, Bilban M, Kodama K, Butte AJ, Staffler G, Zeyda M, Stulnig TM. PMID: 27385318; PMCID: PMC5072410.
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PubMed Mentions:
9 Fields:
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Microfluidic single-cell transcriptional analysis rationally identifies novel surface marker profiles to enhance cell-based therapies. Nat Commun. 2016 06 21; 7:11945.
Rennert RC, Januszyk M, Sorkin M, Rodrigues M, Maan ZN, Duscher D, Whittam AJ, Kosaraju R, Chung MT, Paik K, Li AY, Findlay M, Glotzbach JP, Butte AJ, Gurtner GC. PMID: 27324848; PMCID: PMC5512622.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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A patient-level data meta-analysis of standard-of-care treatments from eight prostate cancer clinical trials. Sci Data. 2016 May 10; 3:160027.
Geifman N, Butte AJ. PMID: 27163794; PMCID: PMC4862324.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Cross-tissue Analysis of Gene and Protein Expression in Normal and Cancer Tissues. Sci Rep. 2016 05 04; 6:24799.
Kosti I, Jain N, Aran D, Butte AJ, Sirota M. PMID: 27142790; PMCID: PMC4855174.
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PubMed Mentions:
96 Fields:
Translation:
Humans
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Constraints on Biological Mechanism from Disease Comorbidity Using Electronic Medical Records and Database of Genetic Variants. PLoS Comput Biol. 2016 Apr; 12(4):e1004885.
Bagley SC, Sirota M, Chen R, Butte AJ, Altman RB. PMID: 27115429; PMCID: PMC4846031.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Expression-Based Genome-Wide Association Study Links Vitamin D-Binding Protein With Autoantigenicity in Type 1 Diabetes. Diabetes. 2016 May; 65(5):1341-9.
Kodama K, Zhao Z, Toda K, Yip L, Fuhlbrigge R, Miao D, Fathman CG, Yamada S, Butte AJ, Yu L. PMID: 26983959; PMCID: PMC4839207.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Leveraging big data to transform target selection and drug discovery. Clin Pharmacol Ther. 2016 Mar; 99(3):285-97.
Chen B, Butte AJ. PMID: 26659699; PMCID: PMC4785018.
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PubMed Mentions:
62 Fields:
Translation:
Humans
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Corrigendum: Systematic pan-cancer analysis of tumour purity. Nat Commun. 2016 Feb 05; 7:10707.
Aran D, Sirota M, Butte AJ. PMID: 26848121; PMCID: PMC4748227.
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PubMed Mentions:
15 Fields:
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ZeitZeiger: supervised learning for high-dimensional data from an oscillatory system. Nucleic Acids Res. 2016 05 05; 44(8):e80.
Hughey JJ, Hastie T, Butte AJ. PMID: 26819407; PMCID: PMC4856978.
View in:
PubMed Mentions:
47 Fields:
Translation:
Animals
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Compendium of Immune Signatures Identifies Conserved and Species-Specific Biology in Response to Inflammation. Immunity. 2016 Jan 19; 44(1):194-206.
Godec J, Tan Y, Liberzon A, Tamayo P, Bhattacharya S, Butte AJ, Mesirov JP, Haining WN. PMID: 26795250; PMCID: PMC5330663.
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PubMed Mentions:
164 Fields:
Translation:
HumansAnimalsCells
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DO CANCER CLINICAL TRIAL POPULATIONS TRULY REPRESENT CANCER PATIENTS? A COMPARISON OF OPEN CLINICAL TRIALS TO THE CANCER GENOME ATLAS. Pac Symp Biocomput. 2016; 21:309-20.
Geifman N, Butte AJ. PMID: 26776196; PMCID: PMC4961464.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
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Genetic analysis in a patient with nine primary malignant neoplasms: a rare case of Li-Fraumeni syndrome. Oncol Rep. 2016 Mar; 35(3):1519-28.
Li X, Kang J, Pan Q, Sikora-Wohlfeld W, Zhao D, Meng C, Bai C, Patwardhan A, Chen R, Ren H, Butte AJ, Ding K. PMID: 26707089.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Immune modulators in disease: integrating knowledge from the biomedical literature and gene expression. J Am Med Inform Assoc. 2016 05; 23(3):617-26.
Geifman N, Bhattacharya S, Butte AJ. PMID: 26661719; PMCID: PMC4901376.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
Systematic pan-cancer analysis of tumour purity. Nat Commun. 2015 Dec 04; 6:8971.
Aran D, Sirota M, Butte AJ. PMID: 26634437; PMCID: PMC4671203.
View in:
PubMed Mentions:
618 Fields:
Translation:
Humans
-
Opening clinical trial data: are the voluntary data-sharing portals enough? BMC Med. 2015 Nov 11; 13:280.
Geifman N, Bollyky J, Bhattacharya S, Butte AJ. PMID: 26560699; PMCID: PMC4642633.
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PubMed Mentions:
21 Fields:
Translation:
Humans
-
Relating Chemical Structure to Cellular Response: An Integrative Analysis of Gene Expression, Bioactivity, and Structural Data Across 11,000 Compounds. CPT Pharmacometrics Syst Pharmacol. 2015 Oct; 4(10):576-84.
Chen B, Greenside P, Paik H, Sirota M, Hadley D, Butte AJ. PMID: 26535158; PMCID: PMC4625862.
View in:
PubMed Mentions:
25 Fields:
-
Reanalysis of the Rituximab in ANCA-Associated Vasculitis trial identifies granulocyte subsets as a novel early marker of successful treatment. Arthritis Res Ther. 2015 Sep 21; 17:262.
Nasrallah M, Pouliot Y, Hartmann B, Dunn P, Thomson E, Wiser J, Butte AJ. PMID: 26387933; PMCID: PMC4576403.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCellsCTClinical Trials
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Achieving high-sensitivity for clinical applications using augmented exome sequencing. Genome Med. 2015; 7:71.
Patwardhan A, Harris J, Leng N, Bartha G, Church DM, Luo S, Haudenschild C, Pratt M, Zook J, Salit M, Tirch J, Morra M, Chervitz S, Li M, Clark M, Garcia S, Chandratillake G, Kirk S, Ashley E, Snyder M, Altman R, Bustamante C, Butte AJ, West J, Chen R. PMID: 26269718; PMCID: PMC4534066.
View in:
PubMed Mentions:
28 Fields:
Translation:
Humans
-
Serological targeted analysis of an ITIH4 peptide isoform: a preterm birth biomarker and its associated SNP implications. J Genet Genomics. 2015 Sep 20; 42(9):507-10.
Tan Z, Hu Z, Cai EY, Alev C, Yang T, Li Z, Sung J, El-Sayed YY, Shaw GM, Stevenson DK, Butte AJ, Sheng G, Sylvester KG, Cohen HJ, Ling XB. PMID: 26408095; PMCID: PMC11186666.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
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Relating hepatocellular carcinoma tumor samples and cell lines using gene expression data in translational research. BMC Med Genomics. 2015; 8 Suppl 2:S5.
Chen B, Sirota M, Fan-Minogue H, Hadley D, Butte AJ. PMID: 26043652; PMCID: PMC4460709.
View in:
PubMed Mentions:
43 Fields:
Translation:
HumansCells
-
ClinGen--the Clinical Genome Resource. N Engl J Med. 2015 06 04; 372(23):2235-42.
Rehm HL, Berg JS, Brooks LD, Bustamante CD, Evans JP, Landrum MJ, Ledbetter DH, Maglott DR, Martin CL, Nussbaum RL, Plon SE, Ramos EM, Sherry ST, Watson MS, ClinGen. PMID: 26014595; PMCID: PMC4474187.
View in:
PubMed Mentions:
627 Fields:
Translation:
Humans
-
The receptor CD44 is associated with systemic insulin resistance and proinflammatory macrophages in human adipose tissue. Diabetologia. 2015 Jul; 58(7):1579-86.
Liu LF, Kodama K, Wei K, Tolentino LL, Choi O, Engleman EG, Butte AJ, McLaughlin T. PMID: 25952479.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansCells
-
Heterogeneity in recent-onset type 1 diabetes - a clinical trial perspective. Diabetes Metab Res Rev. 2015 Sep; 31(6):588-94.
Bollyky JB, Xu P, Butte AJ, Wilson DM, Beam CA, Greenbaum CJ, Type 1 Diabetes TrialNet Study Group. PMID: 25689602; PMCID: PMC4815427.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
A survey of current trends in computational drug repositioning. Brief Bioinform. 2016 Jan; 17(1):2-12.
Li J, Zheng S, Chen B, Butte AJ, Swamidass SJ, Lu Z. PMID: 25832646; PMCID: PMC4719067.
View in:
PubMed Mentions:
214 Fields:
Translation:
HumansCells
-
Robust meta-analysis of gene expression using the elastic net. Nucleic Acids Res. 2015 Jul 13; 43(12):e79.
Hughey JJ, Butte AJ. PMID: 25829177; PMCID: PMC4499117.
View in:
PubMed Mentions:
71 Fields:
Translation:
Humans
-
Repurpose terbutaline sulfate for amyotrophic lateral sclerosis using electronic medical records. Sci Rep. 2015 Mar 05; 5:8580.
Paik H, Chung AY, Park HC, Park RW, Suk K, Kim J, Kim H, Lee K, Butte AJ. PMID: 25739475; PMCID: PMC4894399.
View in:
PubMed Mentions:
34 Fields:
Translation:
Humans
-
Variation in the human immune system is largely driven by non-heritable influences. Cell. 2015 Jan 15; 160(1-2):37-47.
Brodin P, Jojic V, Gao T, Bhattacharya S, Angel CJ, Furman D, Shen-Orr S, Dekker CL, Swan GE, Butte AJ, Maecker HT, Davis MM. PMID: 25594173; PMCID: PMC4302727.
View in:
PubMed Mentions:
484 Fields:
Translation:
Humans
-
Characteristics of drug combination therapy in oncology by analyzing clinical trial data on ClinicalTrials.gov. Pac Symp Biocomput. 2015; 68-79.
Wu M, Sirota M, Butte AJ, Chen B. PMID: 25592569; PMCID: PMC4361221.
View in:
PubMed Mentions:
28 Fields:
Translation:
Humans
-
A systematic assessment of linking gene expression with genetic variants for prioritizing candidate targets. Pac Symp Biocomput. 2015; 383-94.
Fan-Minogue H, Chen B, Sikora-Wohlfeld W, Sirota M, Butte AJ. PMID: 25592598; PMCID: PMC4299914.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Aging disrupts cell subpopulation dynamics and diminishes the function of mesenchymal stem cells. Sci Rep. 2014 Nov 21; 4:7144.
Duscher D, Rennert RC, Januszyk M, Anghel E, Maan ZN, Whittam AJ, Perez MG, Kosaraju R, Hu MS, Walmsley GG, Atashroo D, Khong S, Butte AJ, Gurtner GC. PMID: 25413454; PMCID: PMC4239576.
View in:
PubMed Mentions:
83 Fields:
Translation:
HumansAnimalsCells
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Anti-CD44 antibody treatment lowers hyperglycemia and improves insulin resistance, adipose inflammation, and hepatic steatosis in diet-induced obese mice. Diabetes. 2015 Mar; 64(3):867-75.
Kodama K, Toda K, Morinaga S, Yamada S, Butte AJ. PMID: 25294945; PMCID: PMC4392898.
View in:
PubMed Mentions:
44 Fields:
Translation:
Animals
-
The Integrative Human Microbiome Project: dynamic analysis of microbiome-host omics profiles during periods of human health and disease. Cell Host Microbe. 2014 Sep 10; 16(3):276-89.
Integrative HMP (iHMP) Research Network Consortium. PMID: 25211071; PMCID: PMC5109542.
View in:
PubMed Mentions:
235 Fields:
Translation:
HumansCells
-
Organ size control is dominant over Rb family inactivation to restrict proliferation in vivo. Cell Rep. 2014 Jul 24; 8(2):371-81.
Ehmer U, Zmoos AF, Auerbach RK, Vaka D, Butte AJ, Kay MA, Sage J. PMID: 25017070; PMCID: PMC4128252.
View in:
PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
-
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer. Nature. 2014 Jun 12; 510(7504):283-7.
Mazur PK, Reynoird N, Khatri P, Jansen PW, Wilkinson AW, Liu S, Barbash O, Van Aller GS, Huddleston M, Dhanak D, Tummino PJ, Kruger RG, Garcia BA, Butte AJ, Vermeulen M, Sage J, Gozani O. PMID: 24847881; PMCID: PMC4122675.
View in:
PubMed Mentions:
205 Fields:
Translation:
HumansAnimalsCells
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Whole-exome sequencing reveals TopBP1 as a novel gene in idiopathic pulmonary arterial hypertension. Am J Respir Crit Care Med. 2014 May 15; 189(10):1260-72.
de Jesus Perez VA, Yuan K, Lyuksyutova MA, Dewey F, Orcholski ME, Shuffle EM, Mathur M, Yancy L, Rojas V, Li CG, Cao A, Alastalo TP, Khazeni N, Cimprich KA, Butte AJ, Ashley E, Zamanian RT. PMID: 24702692; PMCID: PMC4225850.
View in:
PubMed Mentions:
53 Fields:
Translation:
Humans
-
ImmPort: disseminating data to the public for the future of immunology. Immunol Res. 2014 May; 58(2-3):234-9.
Bhattacharya S, Andorf S, Gomes L, Dunn P, Schaefer H, Pontius J, Berger P, Desborough V, Smith T, Campbell J, Thomson E, Monteiro R, Guimaraes P, Walters B, Wiser J, Butte AJ. PMID: 24791905.
View in:
PubMed Mentions:
448 Fields:
Translation:
Humans
-
Disease risk factors identified through shared genetic architecture and electronic medical records. Sci Transl Med. 2014 Apr 30; 6(234):234ra57.
Li L, Ruau DJ, Patel CJ, Weber SC, Chen R, Tatonetti NP, Dudley JT, Butte AJ. PMID: 24786325; PMCID: PMC4323098.
View in:
PubMed Mentions:
32 Fields:
Translation:
Humans
-
Diabetes irreversibly depletes bone marrow-derived mesenchymal progenitor cell subpopulations. Diabetes. 2014 Sep; 63(9):3047-56.
Januszyk M, Sorkin M, Glotzbach JP, Vial IN, Maan ZN, Rennert RC, Duscher D, Thangarajah H, Longaker MT, Butte AJ, Gurtner GC. PMID: 24740572; PMCID: PMC4429348.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
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Collaborative biomedicine in the age of big data: the case of cancer. J Med Internet Res. 2014 Apr 07; 16(4):e101.
Shaikh AR, Butte AJ, Schully SD, Dalton WS, Khoury MJ, Hesse BW. PMID: 24711045; PMCID: PMC4004150.
View in:
PubMed Mentions:
24 Fields:
Translation:
Humans
-
Mutations in NGLY1 cause an inherited disorder of the endoplasmic reticulum-associated degradation pathway. Genet Med. 2014 Oct; 16(10):751-8.
Enns GM, Shashi V, Bainbridge M, Gambello MJ, Zahir FR, Bast T, Crimian R, Schoch K, Platt J, Cox R, Bernstein JA, Scavina M, Walter RS, Bibb A, Jones M, Hegde M, Graham BH, Need AC, Oviedo A, Schaaf CP, Boyle S, Butte AJ, Chen R, Chen R, Clark MJ, Haraksingh R, FORGE Canada Consortium, Cowan TM, He P, Langlois S, Zoghbi HY, Snyder M, Gibbs RA, Freeze HH, Goldstein DB. PMID: 24651605; PMCID: PMC4243708.
View in:
PubMed Mentions:
101 Fields:
Translation:
HumansCells
-
A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma. Cancer Res. 2014 May 15; 74(10):2892-902.
Chen R, Khatri P, Mazur PK, Polin M, Zheng Y, Vaka D, Hoang CD, Shrager J, Xu Y, Vicent S, Butte AJ, Sweet-Cordero EA. PMID: 24654231; PMCID: PMC4084668.
View in:
PubMed Mentions:
82 Fields:
Translation:
HumansAnimalsCells
-
Clinical interpretation and implications of whole-genome sequencing. JAMA. 2014 Mar 12; 311(10):1035-45.
Dewey FE, Grove ME, Pan C, Goldstein BA, Bernstein JA, Chaib H, Merker JD, Goldfeder RL, Enns GM, David SP, Pakdaman N, Ormond KE, Caleshu C, Kingham K, Klein TE, Whirl-Carrillo M, Sakamoto K, Wheeler MT, Butte AJ, Ford JM, Boxer L, Ioannidis JP, Yeung AC, Altman RB, Assimes TL, Snyder M, Ashley EA, Quertermous T. PMID: 24618965; PMCID: PMC4119063.
View in:
PubMed Mentions:
222 Fields:
Translation:
Humans
-
Investigation of maternal environmental exposures in association with self-reported preterm birth. Reprod Toxicol. 2014 Jun; 45:1-7.
Patel CJ, Yang T, Hu Z, Wen Q, Sung J, El-Sayed YY, Cohen H, Gould J, Stevenson DK, Shaw GM, Ling XB, Butte AJ, March of Dimes Prematurity Research Center at Stanford University School of Medicine. PMID: 24373932; PMCID: PMC4316205.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansPHPublic Health
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Network medicine in disease analysis and therapeutics. Clin Pharmacol Ther. 2013 Dec; 94(6):627-9.
Chen B, Butte AJ. PMID: 24241637; PMCID: PMC5624966.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Integrating multiple 'omics' analyses identifies serological protein biomarkers for preeclampsia. BMC Med. 2013 Nov 06; 11:236.
Liu LY, Yang T, Ji J, Wen Q, Morgan AA, Jin B, Chen G, Lyell DJ, Stevenson DK, Ling XB, Butte AJ. PMID: 24195779; PMCID: PMC4226208.
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PubMed Mentions:
23 Fields:
Translation:
Humans
-
A common rejection module (CRM) for acute rejection across multiple organs identifies novel therapeutics for organ transplantation. J Exp Med. 2013 Oct 21; 210(11):2205-21.
Khatri P, Roedder S, Kimura N, De Vusser K, Morgan AA, Gong Y, Fischbein MP, Robbins RC, Naesens M, Butte AJ, Sarwal MM. PMID: 24127489; PMCID: PMC3804941.
View in:
PubMed Mentions:
134 Fields:
Translation:
HumansAnimals
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Systematic evaluation of personal genome services for Japanese individuals. J Hum Genet. 2013 Nov; 58(11):734-41.
Kido T, Kawashima M, Nishino S, Swan M, Kamatani N, Butte AJ. PMID: 24067293.
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PubMed Mentions:
4 Fields:
Translation:
Humans
-
A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors. Cancer Discov. 2013 Dec; 3(12):1364-77.
Jahchan NS, Dudley JT, Mazur PK, Flores N, Yang D, Palmerton A, Zmoos AF, Vaka D, Tran KQ, Zhou M, Krasinska K, Riess JW, Neal JW, Khatri P, Park KS, Butte AJ, Sage J. PMID: 24078773; PMCID: PMC3864571.
View in:
PubMed Mentions:
186 Fields:
Translation:
HumansAnimalsCells
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Making it personal: translational bioinformatics. J Am Med Inform Assoc. 2013 Jul-Aug; 20(4):595-6.
Butte AJ, Ohno-Machado L. PMID: 23757438; PMCID: PMC3721179.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Whole genome sequencing in support of wellness and health maintenance. Genome Med. 2013; 5(6):58.
Patel CJ, Sivadas A, Tabassum R, Preeprem T, Zhao J, Arafat D, Chen R, Morgan AA, Martin GS, Brigham KL, Butte AJ, Gibson G. PMID: 23806097; PMCID: PMC3967117.
View in:
PubMed Mentions:
26 Fields:
-
Systematic identification of DNA variants associated with ultraviolet radiation using a novel Geographic-Wide Association Study (GeoWAS). BMC Med Genet. 2013 Jun 20; 14:62.
Hsu I, Chen R, Ramesh A, Corona E, Kang HP, Ruau D, Butte AJ. PMID: 23786662; PMCID: PMC3699381.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Peptidomic Identification of Serum Peptides Diagnosing Preeclampsia. PLoS One. 2013; 8(6):e65571.
Wen Q, Liu LY, Yang T, Alev C, Wu S, Stevenson DK, Sheng G, Butte AJ, Ling XB. PMID: 23840341; PMCID: PMC3686758.
View in:
PubMed Mentions:
23 Fields:
Translation:
Humans
-
Relating genes to function: identifying enriched transcription factors using the ENCODE ChIP-Seq significance tool. Bioinformatics. 2013 Aug 01; 29(15):1922-4.
Auerbach RK, Chen B, Butte AJ. PMID: 23732275; PMCID: PMC3712221.
View in:
PubMed Mentions:
45 Fields:
-
Ethnic differences in the relationship between insulin sensitivity and insulin response: a systematic review and meta-analysis. Diabetes Care. 2013 Jun; 36(6):1789-96.
Kodama K, Tojjar D, Yamada S, Toda K, Patel CJ, Butte AJ. PMID: 23704681; PMCID: PMC3661854.
View in:
PubMed Mentions:
293 Fields:
Translation:
Humans
-
Analysis of the genetic basis of disease in the context of worldwide human relationships and migration. PLoS Genet. 2013 May; 9(5):e1003447.
Corona E, Chen R, Sikora M, Morgan AA, Patel CJ, Ramesh A, Bustamante CD, Butte AJ. PMID: 23717210; PMCID: PMC3662561.
View in:
PubMed Mentions:
46 Fields:
Translation:
Humans
-
Systematic functional regulatory assessment of disease-associated variants. Proc Natl Acad Sci U S A. 2013 Jun 04; 110(23):9607-12.
Karczewski KJ, Dudley JT, Kukurba KR, Chen R, Butte AJ, Montgomery SB, Snyder M. PMID: 23690573; PMCID: PMC3677437.
View in:
PubMed Mentions:
55 Fields:
Translation:
HumansCells
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Altering physiological networks using drugs: steps towards personalized physiology. BMC Med Genomics. 2013; 6 Suppl 2:S7.
Grossman AD, Cohen MJ, Manley GT, Butte AJ. PMID: 23819503; PMCID: PMC3654899.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Immune response profiling identifies autoantibodies specific to Moyamoya patients. Orphanet J Rare Dis. 2013 Mar 21; 8:45.
Sigdel TK, Shoemaker LD, Chen R, Li L, Butte AJ, Sarwal MM, Steinberg GK. PMID: 23518061; PMCID: PMC3648437.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCells
-
Database integration of 4923 publicly-available samples of breast cancer molecular and clinical data. AMIA Jt Summits Transl Sci Proc. 2013; 2013:138-42.
Planey CR, Butte AJ. PMID: 24303324; PMCID: PMC3814460.
View in:
PubMed Mentions:
4
-
Systematic identification of interaction effects between validated genome- and environment-wide associations on Type 2 Diabetes Mellitus. AMIA Jt Summits Transl Sci Proc. 2013; 2013:135.
Patel CJ, Chen R, Kodama K, Ioannidis JP, Butte AJ. PMID: 24303322.
View in:
PubMed Mentions:
2
-
Systematic identification of interaction effects between genome- and environment-wide associations in type 2 diabetes mellitus. Hum Genet. 2013 May; 132(5):495-508.
Patel CJ, Chen R, Kodama K, Ioannidis JP, Butte AJ. PMID: 23334806; PMCID: PMC3625410.
View in:
PubMed Mentions:
64 Fields:
Translation:
Humans
-
Systematic identification of risk factors for Alzheimer's disease through shared genetic architecture and electronic medical records. Pac Symp Biocomput. 2013; 224-35.
Li L, Ruau D, Chen R, Weber S, Butte AJ. PMID: 23424127.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
FoxO6 regulates memory consolidation and synaptic function. Genes Dev. 2012 Dec 15; 26(24):2780-801.
Salih DA, Rashid AJ, Colas D, de la Torre-Ubieta L, Zhu RP, Morgan AA, Santo EE, Ucar D, Devarajan K, Cole CJ, Madison DV, Shamloo M, Butte AJ, Bonni A, Josselyn SA, Brunet A. PMID: 23222102; PMCID: PMC3533081.
View in:
PubMed Mentions:
77 Fields:
Translation:
AnimalsCells
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A nutrient-wide association study on blood pressure. Circulation. 2012 Nov 20; 126(21):2456-64.
Tzoulaki I, Patel CJ, Okamura T, Chan Q, Brown IJ, Miura K, Ueshima H, Zhao L, Van Horn L, Daviglus ML, Stamler J, Butte AJ, Ioannidis JP, Elliott P. PMID: 23093587; PMCID: PMC4105584.
View in:
PubMed Mentions:
76 Fields:
Translation:
Humans
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Transdisciplinary translational science and the case of preterm birth. J Perinatol. 2013 Apr; 33(4):251-8.
Stevenson DK, Shaw GM, Wise PH, Norton ME, Druzin ML, Valantine HA, McFarland DA, March of Dimes Prematurity Research Center at Stanford University School of Medicine. PMID: 23079774; PMCID: PMC3613736.
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PubMed Mentions:
9 Fields:
Translation:
Humans
-
Population genetic inference from personal genome data: impact of ancestry and admixture on human genomic variation. Am J Hum Genet. 2012 Oct 05; 91(4):660-71.
Kidd JM, Gravel S, Byrnes J, Moreno-Estrada A, Musharoff S, Bryc K, Degenhardt JD, Brisbin A, Sheth V, Chen R, McLaughlin SF, Peckham HE, Omberg L, Bormann Chung CA, Stanley S, Pearlstein K, Levandowsky E, Acevedo-Acevedo S, Auton A, Keinan A, Acuña-Alonzo V, Barquera-Lozano R, Canizales-Quinteros S, Eng C, Burchard EG, Russell A, Reynolds A, Clark AG, Reese MG, Lincoln SE, Butte AJ, De La Vega FM, Bustamante CD. PMID: 23040495; PMCID: PMC3484644.
View in:
PubMed Mentions:
61 Fields:
Translation:
Humans
-
A peripheral blood diagnostic test for acute rejection in renal transplantation. Am J Transplant. 2012 Oct; 12(10):2710-8.
Li L, Khatri P, Sigdel TK, Tran T, Ying L, Vitalone MJ, Chen A, Hsieh S, Dai H, Zhang M, Naesens M, Zarkhin V, Sansanwal P, Chen R, Mindrinos M, Xiao W, Benfield M, Ettenger RB, Dharnidharka V, Mathias R, Portale A, McDonald R, Harmon W, Kershaw D, Vehaskari VM, Kamil E, Baluarte HJ, Warady B, Davis R, Butte AJ, Salvatierra O, Sarwal MM. PMID: 23009139; PMCID: PMC4148014.
View in:
PubMed Mentions:
68 Fields:
Translation:
Humans
-
Cross-species functional analysis of cancer-associated fibroblasts identifies a critical role for CLCF1 and IL-6 in non-small cell lung cancer in vivo. Cancer Res. 2012 Nov 15; 72(22):5744-56.
Vicent S, Sayles LC, Vaka D, Khatri P, Gevaert O, Chen R, Zheng Y, Gillespie AK, Clarke N, Xu Y, Shrager J, Hoang CD, Plevritis S, Butte AJ, Sweet-Cordero EA. PMID: 22962265; PMCID: PMC3856949.
View in:
PubMed Mentions:
54 Fields:
Translation:
HumansAnimalsCells
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Sequencing and analysis of a South Asian-Indian personal genome. BMC Genomics. 2012 Aug 31; 13:440.
Gupta R, Ratan A, Rajesh C, Chen R, Kim HL, Burhans R, Miller W, Santhosh S, Davuluri RV, Butte AJ, Schuster SC, Seshagiri S, Thomas G. PMID: 22938532; PMCID: PMC3534380.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
-
Leveraging models of cell regulation and GWAS data in integrative network-based association studies. Nat Genet. 2012 Jul 27; 44(8):841-7.
Califano A, Butte AJ, Friend S, Ideker T, Schadt E. PMID: 22836096; PMCID: PMC3593099.
View in:
PubMed Mentions:
139 Fields:
Translation:
Humans
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Identification of cell surface targets through meta-analysis of microarray data. Neoplasia. 2012 Jul; 14(7):666-9.
Haeberle H, Dudley JT, Liu JT, Butte AJ, Contag CH. PMID: 22904683; PMCID: PMC3421962.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Data-driven integration of epidemiological and toxicological data to select candidate interacting genes and environmental factors in association with disease. Bioinformatics. 2012 Jun 15; 28(12):i121-6.
Patel CJ, Chen R, Butte AJ. PMID: 22689751; PMCID: PMC3371861.
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PubMed Mentions:
19 Fields:
Translation:
Humans
-
Integrative approach to pain genetics identifies pain sensitivity loci across diseases. PLoS Comput Biol. 2012; 8(6):e1002538.
Ruau D, Dudley JT, Chen R, Phillips NG, Swan GE, Lazzeroni LC, Clark JD, Butte AJ, Angst MS. PMID: 22685391; PMCID: PMC3369906.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Human genomic disease variants: a neutral evolutionary explanation. Genome Res. 2012 Aug; 22(8):1383-94.
Dudley JT, Kim Y, Liu L, Markov GJ, Gerold K, Chen R, Butte AJ, Kumar S. PMID: 22665443; PMCID: PMC3409252.
View in:
PubMed Mentions:
25 Fields:
Translation:
Humans
-
Clinical utility of sequence-based genotype compared with that derivable from genotyping arrays. J Am Med Inform Assoc. 2012 Jun; 19(e1):e21-7.
Morgan AA, Chen R, Butte AJ. PMID: 22718036; PMCID: PMC3392859.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Translational bioinformatics: data-driven drug discovery and development. Clin Pharmacol Ther. 2012 Jun; 91(6):949-52.
Butte AJ, Ito S. PMID: 22609903.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimals
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Integration of disease-specific single nucleotide polymorphisms, expression quantitative trait loci and coexpression networks reveal novel candidate genes for type 2 diabetes. Diabetologia. 2012 Aug; 55(8):2205-13.
Kang HP, Yang X, Chen R, Zhang B, Corona E, Schadt EE, Butte AJ. PMID: 22584726; PMCID: PMC3390705.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansAnimals
-
Neonatal Informatics: Transforming Neonatal Care Through Translational Bioinformatics. Neoreviews. 2012 May 01; 13(5):e281-e284.
Palma JP, Benitz WE, Tarczy-Hornoch P, Butte AJ, Longhurst CA. PMID: 22924023; PMCID: PMC3424284.
View in:
PubMed Mentions:
4 Fields:
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Expression-based genome-wide association study links the receptor CD44 in adipose tissue with type 2 diabetes. Proc Natl Acad Sci U S A. 2012 May 01; 109(18):7049-54.
Kodama K, Horikoshi M, Toda K, Yamada S, Hara K, Irie J, Sirota M, Morgan AA, Chen R, Ohtsu H, Maeda S, Kadowaki T, Butte AJ. PMID: 22499789; PMCID: PMC3344989.
View in:
PubMed Mentions:
96 Fields:
Translation:
HumansAnimalsCells
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Type 2 diabetes risk alleles demonstrate extreme directional differentiation among human populations, compared to other diseases. PLoS Genet. 2012; 8(4):e1002621.
Chen R, Corona E, Sikora M, Dudley JT, Morgan AA, Moreno-Estrada A, Nilsen GB, Ruau D, Lincoln SE, Bustamante CD, Butte AJ. PMID: 22511877; PMCID: PMC3325177.
View in:
PubMed Mentions:
67 Fields:
Translation:
Humans
-
Quantifying multi-ethnic representation in genetic studies of high mortality diseases. AMIA Jt Summits Transl Sci Proc. 2012; 2012:11-8.
Chen R, Dudley JT, Ruau D, Butte AJ. PMID: 22779041; PMCID: PMC3392055.
View in:
PubMed Mentions:
1
-
Coanalysis of GWAS with eQTLs reveals disease-tissue associations. AMIA Jt Summits Transl Sci Proc. 2012; 2012:35-41.
Kang HP, Morgan AA, Chen R, Schadt EE, Butte AJ. PMID: 22779046; PMCID: PMC3392070.
View in:
PubMed Mentions:
8
-
Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell. 2012 Mar 16; 148(6):1293-307.
Chen R, Mias GI, Li-Pook-Than J, Jiang L, Lam HY, Chen R, Miriami E, Karczewski KJ, Hariharan M, Dewey FE, Cheng Y, Clark MJ, Im H, Habegger L, Balasubramanian S, O'Huallachain M, Dudley JT, Hillenmeyer S, Haraksingh R, Sharon D, Euskirchen G, Lacroute P, Bettinger K, Boyle AP, Kasowski M, Grubert F, Seki S, Garcia M, Whirl-Carrillo M, Gallardo M, Blasco MA, Greenberg PL, Snyder P, Klein TE, Altman RB, Butte AJ, Ashley EA, Gerstein M, Nadeau KC, Tang H, Snyder M. PMID: 22424236; PMCID: PMC3341616.
View in:
PubMed Mentions:
529 Fields:
Translation:
HumansCells
-
Systematic evaluation of environmental factors: persistent pollutants and nutrients correlated with serum lipid levels. Int J Epidemiol. 2012 Jun; 41(3):828-43.
Patel CJ, Cullen MR, Ioannidis JP, Butte AJ. PMID: 22421054; PMCID: PMC3396318.
View in:
PubMed Mentions:
73 Fields:
Translation:
HumansPHPublic Health
-
Evolutionary meta-analysis of association studies reveals ancient constraints affecting disease marker discovery. Mol Biol Evol. 2012 Sep; 29(9):2087-94.
Dudley JT, Chen R, Sanderford M, Butte AJ, Kumar S. PMID: 22389448; PMCID: PMC3424407.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansAnimals
-
Multiplex meta-analysis of RNA expression to identify genes with variants associated with immune dysfunction. J Am Med Inform Assoc. 2012 Mar-Apr; 19(2):284-8.
Morgan AA, Pyrgos VJ, Nadeau KC, Williamson PR, Butte AJ. PMID: 22319178; PMCID: PMC3277634.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
-
Ten years of pathway analysis: current approaches and outstanding challenges. PLoS Comput Biol. 2012; 8(2):e1002375.
Khatri P, Sirota M, Butte AJ. PMID: 22383865; PMCID: PMC3285573.
View in:
PubMed Mentions:
743 Fields:
Translation:
HumansAnimals
-
Sex differences in reported pain across 11,000 patients captured in electronic medical records. J Pain. 2012 Mar; 13(3):228-34.
Ruau D, Liu LY, Clark JD, Angst MS, Butte AJ. PMID: 22245360; PMCID: PMC3293998.
View in:
PubMed Mentions:
95 Fields:
Translation:
Humans
-
Performance comparison of whole-genome sequencing platforms. Nat Biotechnol. 2011 Dec 18; 30(1):78-82.
Lam HY, Clark MJ, Chen R, Chen R, Natsoulis G, O'Huallachain M, Dewey FE, Habegger L, Ashley EA, Gerstein MB, Butte AJ, Ji HP, Snyder M. PMID: 22178993; PMCID: PMC4076012.
View in:
PubMed Mentions:
172 Fields:
Translation:
Humans
-
ProfileChaser: searching microarray repositories based on genome-wide patterns of differential expression. Bioinformatics. 2011 Dec 01; 27(23):3317-8.
Engreitz JM, Chen R, Morgan AA, Dudley JT, Mallelwar R, Butte AJ. PMID: 21967760; PMCID: PMC3223361.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
-
Performance comparison of exome DNA sequencing technologies. Nat Biotechnol. 2011 Sep 25; 29(10):908-14.
Clark MJ, Chen R, Lam HY, Karczewski KJ, Chen R, Euskirchen G, Butte AJ, Snyder M. PMID: 21947028; PMCID: PMC4127531.
View in:
PubMed Mentions:
244 Fields:
Translation:
HumansCells
-
Phased whole-genome genetic risk in a family quartet using a major allele reference sequence. PLoS Genet. 2011 Sep; 7(9):e1002280.
Dewey FE, Chen R, Cordero SP, Ormond KE, Caleshu C, Karczewski KJ, Whirl-Carrillo M, Wheeler MT, Dudley JT, Byrnes JK, Cornejo OE, Knowles JW, Woon M, Sangkuhl K, Gong L, Thorn CF, Hebert JM, Capriotti E, David SP, Pavlovic A, West A, Thakuria JV, Ball MP, Zaranek AW, Rehm HL, Church GM, West JS, Bustamante CD, Snyder M, Altman RB, Klein TE, Butte AJ, Ashley EA. PMID: 21935354; PMCID: PMC3174201.
View in:
PubMed Mentions:
85 Fields:
Translation:
HumansCells
-
Progressive histological damage in renal allografts is associated with expression of innate and adaptive immunity genes. Kidney Int. 2011 Dec; 80(12):1364-76.
Naesens M, Khatri P, Li L, Sigdel TK, Vitalone MJ, Chen R, Butte AJ, Salvatierra O, Sarwal MM. PMID: 21881554; PMCID: PMC4492284.
View in:
PubMed Mentions:
50 Fields:
Translation:
Humans
-
Sex differences in disease risk from reported genome-wide association study findings. Hum Genet. 2012 Mar; 131(3):353-64.
Liu LY, Schaub MA, Sirota M, Butte AJ. PMID: 21858542; PMCID: PMC3260375.
View in:
PubMed Mentions:
44 Fields:
Translation:
Humans
-
Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease. Sci Transl Med. 2011 Aug 17; 3(96):96ra76.
Dudley JT, Sirota M, Shenoy M, Pai RK, Roedder S, Chiang AP, Morgan AA, Sarwal MM, Pasricha PJ, Butte AJ. PMID: 21849664; PMCID: PMC3479650.
View in:
PubMed Mentions:
302 Fields:
Translation:
Humans
-
Discovery and preclinical validation of drug indications using compendia of public gene expression data. Sci Transl Med. 2011 Aug 17; 3(96):96ra77.
Sirota M, Dudley JT, Kim J, Chiang AP, Morgan AA, Sweet-Cordero A, Sage J, Butte AJ. PMID: 21849665; PMCID: PMC3502016.
View in:
PubMed Mentions:
391 Fields:
Translation:
HumansAnimals
-
Identification of an IFN-γ/mast cell axis in a mouse model of chronic asthma. J Clin Invest. 2011 Aug; 121(8):3133-43.
Yu M, Eckart MR, Morgan AA, Mukai K, Butte AJ, Tsai M, Galli SJ. PMID: 21737883; PMCID: PMC3148724.
View in:
PubMed Mentions:
60 Fields:
Translation:
AnimalsCells
-
Computationally translating molecular discoveries into tools for medicine: translational bioinformatics articles now featured in JAMIA. J Am Med Inform Assoc. 2011 Jul-Aug; 18(4):352-3.
Butte AJ, Shah NH. PMID: 21672904; PMCID: PMC3128419.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Applications of translational bioinformatics in transplantation. Clin Pharmacol Ther. 2011 Aug; 90(2):323-7.
Khatri P, Sarwal MM, Butte AJ. PMID: 21716268; PMCID: PMC3476839.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
The role of bioinformatics in studying rheumatic and autoimmune disorders. Nat Rev Rheumatol. 2011 06 21; 7(8):489-94.
Sirota M, Butte AJ. PMID: 21691330.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Exploiting drug-disease relationships for computational drug repositioning. Brief Bioinform. 2011 Jul; 12(4):303-11.
Dudley JT, Deshpande T, Butte AJ. PMID: 21690101; PMCID: PMC3137933.
View in:
PubMed Mentions:
193 Fields:
Translation:
HumansAnimals
-
Predicting adverse drug reactions using publicly available PubChem BioAssay data. Clin Pharmacol Ther. 2011 Jul; 90(1):90-9.
Pouliot Y, Chiang AP, Butte AJ. PMID: 21613989; PMCID: PMC3464971.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansAnimals
-
Transmission distortion in Crohn's disease risk gene ATG16L1 leads to sex difference in disease association. Inflamm Bowel Dis. 2012 Feb; 18(2):312-22.
Liu LY, Schaub MA, Sirota M, Butte AJ. PMID: 21618365; PMCID: PMC3165065.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
Translational bioinformatics: linking knowledge across biological and clinical realms. J Am Med Inform Assoc. 2011 Jul-Aug; 18(4):354-7.
Sarkar IN, Butte AJ, Lussier YA, Tarczy-Hornoch P, Ohno-Machado L. PMID: 21561873; PMCID: PMC3128415.
View in:
PubMed Mentions:
32 Fields:
Translation:
Humans
-
Comparison of automated and human assignment of MeSH terms on publicly-available molecular datasets. J Biomed Inform. 2011 Dec; 44 Suppl 1:S39-S43.
Ruau D, Mbagwu M, Dudley JT, Krishnan V, Butte AJ. PMID: 21420508; PMCID: PMC3155012.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Transplantomics and biomarkers in organ transplantation: a report from the first international conference. Transplantation. 2011 Feb 27; 91(4):379-82.
Sarwal MM, Benjamin J, Butte AJ, Davis MM, Wood K, Chapman J. PMID: 21278631; PMCID: PMC3762499.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Computational prediction and experimental validation associating FABP-1 and pancreatic adenocarcinoma with diabetes. BMC Gastroenterol. 2011 Jan 20; 11:5.
Sharaf RN, Butte AJ, Montgomery KD, Pai R, Dudley JT, Pasricha PJ. PMID: 21251264; PMCID: PMC3037918.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
Matching cancer genomes to established cell lines for personalized oncology. Pac Symp Biocomput. 2011; 243-52.
Dudley JT, Chen R, Butte AJ. PMID: 21121052; PMCID: PMC3477496.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
The reference human genome demonstrates high risk of type 1 diabetes and other disorders. Pac Symp Biocomput. 2011; 231-42.
Chen R, Butte AJ. PMID: 21121051; PMCID: PMC3732491.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
Protein microarrays discover angiotensinogen and PRKRIP1 as novel targets for autoantibodies in chronic renal disease. Mol Cell Proteomics. 2011 Mar; 10(3):M110.000497.
Butte AJ, Sigdel TK, Wadia PP, Miklos DB, Sarwal MM. PMID: 21183621; PMCID: PMC3047141.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Content-based microarray search using differential expression profiles. BMC Bioinformatics. 2010 Dec 21; 11:603.
Engreitz JM, Morgan AA, Dudley JT, Chen R, Thathoo R, Altman RB, Butte AJ. PMID: 21172034; PMCID: PMC3022631.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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In silico research in the era of cloud computing. Nat Biotechnol. 2010 Nov; 28(11):1181-5.
Dudley JT, Butte AJ. PMID: 21057489; PMCID: PMC3755123.
View in:
PubMed Mentions:
38 Fields:
-
Comparison of multiplex meta analysis techniques for understanding the acute rejection of solid organ transplants. BMC Bioinformatics. 2010 Oct 28; 11 Suppl 9:S6.
Morgan AA, Khatri P, Jones RH, Sarwal MM, Butte AJ. PMID: 21044364; PMCID: PMC2967747.
View in:
PubMed Mentions:
19 Fields:
-
Latent physiological factors of complex human diseases revealed by independent component analysis of clinarrays. BMC Bioinformatics. 2010 Oct 28; 11 Suppl 9:S4.
Chen DP, Dudley JT, Butte AJ. PMID: 21044362; PMCID: PMC2967745.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
An integrative method for scoring candidate genes from association studies: application to warfarin dosing. BMC Bioinformatics. 2010 Oct 28; 11 Suppl 9:S9.
Tatonetti NP, Dudley JT, Sagreiya H, Butte AJ, Altman RB. PMID: 21044367; PMCID: PMC2967750.
View in:
PubMed Mentions:
11 Fields:
-
Non-synonymous and synonymous coding SNPs show similar likelihood and effect size of human disease association. PLoS One. 2010 Oct 22; 5(10):e13574.
Chen R, Davydov EV, Sirota M, Butte AJ. PMID: 21042586; PMCID: PMC2962641.
View in:
PubMed Mentions:
93 Fields:
Translation:
Humans
-
Differentially expressed RNA from public microarray data identifies serum protein biomarkers for cross-organ transplant rejection and other conditions. PLoS Comput Biol. 2010 Sep 23; 6(9).
Chen R, Sigdel TK, Li L, Kambham N, Dudley JT, Hsieh SC, Klassen RB, Chen A, Caohuu T, Morgan AA, Valantine HA, Khush KK, Sarwal MM, Butte AJ. PMID: 20885780; PMCID: PMC2944782.
View in:
PubMed Mentions:
40 Fields:
Translation:
Humans
-
Special article: an optimistic prognosis for the clinical utility of laboratory test data. Anesth Analg. 2010 Oct; 111(4):1026-35.
Zheng M, Ravindran P, Wang J, Epstein RH, Chen DP, Butte AJ, Peltz G. PMID: 20810674.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Dynamic microRNA expression programs during cardiac differentiation of human embryonic stem cells: role for miR-499. Circ Cardiovasc Genet. 2010 Oct; 3(5):426-35.
Wilson KD, Hu S, Venkatasubrahmanyam S, Fu JD, Sun N, Abilez OJ, Baugh JJ, Jia F, Ghosh Z, Li RA, Butte AJ, Wu JC. PMID: 20733065; PMCID: PMC3057038.
View in:
PubMed Mentions:
98 Fields:
Translation:
HumansAnimalsCells
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Extreme evolutionary disparities seen in positive selection across seven complex diseases. PLoS One. 2010 Aug 17; 5(8):e12236.
Corona E, Dudley JT, Butte AJ. PMID: 20808933; PMCID: PMC2923198.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansCells
-
Translational bioinformatics in the cloud: an affordable alternative. Genome Med. 2010 Aug 06; 2(8):51.
Dudley JT, Pouliot Y, Chen R, Morgan AA, Butte AJ. PMID: 20691073; PMCID: PMC2945008.
View in:
PubMed Mentions:
26 Fields:
-
Drug discovery in a multidimensional world: systems, patterns, and networks. J Cardiovasc Transl Res. 2010 Oct; 3(5):438-47.
Dudley JT, Schadt E, Sirota M, Butte AJ, Ashley E. PMID: 20677029.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansAnimals
-
Biomarker and drug discovery for gastroenterology through translational bioinformatics. Gastroenterology. 2010 Sep; 139(3):735-41, 741.e1.
Dudley JT, Butte AJ. PMID: 20650279.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
-
Getting from genes to function in lung disease: a National Heart, Lung, and Blood Institute workshop report. Am J Respir Crit Care Med. 2010 Sep 15; 182(6):732-7.
Ober C, Butte AJ, Elias JA, Lusis AJ, Gan W, Banks-Schlegel S, Schwartz D. PMID: 20558629; PMCID: PMC2949401.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus. PLoS One. 2010 May 20; 5(5):e10746.
Patel CJ, Bhattacharya J, Butte AJ. PMID: 20505766; PMCID: PMC2873978.
View in:
PubMed Mentions:
255 Fields:
Translation:
Humans
-
Likelihood ratios for genome medicine. Genome Med. 2010 May 17; 2(5):30.
Morgan AA, Chen R, Butte AJ. PMID: 20497613; PMCID: PMC2887074.
View in:
PubMed Mentions:
13 Fields:
-
Current methodologies for translational bioinformatics. J Biomed Inform. 2010 Jun; 43(3):355-7.
Lussier YA, Butte AJ, Hunter L. PMID: 20470899; PMCID: PMC2894568.
View in:
PubMed Mentions:
3 Fields:
-
Predicting environmental chemical factors associated with disease-related gene expression data. BMC Med Genomics. 2010 May 06; 3:17.
Patel CJ, Butte AJ. PMID: 20459635; PMCID: PMC2880288.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansPHPublic Health
-
Clinical assessment incorporating a personal genome. Lancet. 2010 May 01; 375(9725):1525-35.
Ashley EA, Butte AJ, Wheeler MT, Chen R, Klein TE, Dewey FE, Dudley JT, Ormond KE, Pavlovic A, Morgan AA, Pushkarev D, Neff NF, Hudgins L, Gong L, Hodges LM, Berlin DS, Thorn CF, Sangkuhl K, Hebert JM, Woon M, Sagreiya H, Whaley R, Knowles JW, Chou MF, Thakuria JV, Rosenbaum AM, Zaranek AW, Church GM, Greely HT, Quake SR, Altman RB. PMID: 20435227; PMCID: PMC2937184.
View in:
PubMed Mentions:
304 Fields:
Translation:
Humans
-
Challenges in the clinical application of whole-genome sequencing. Lancet. 2010 May 15; 375(9727):1749-51.
Ormond KE, Wheeler MT, Hudgins L, Klein TE, Butte AJ, Altman RB, Ashley EA, Greely HT. PMID: 20434765.
View in:
PubMed Mentions:
98 Fields:
Translation:
Humans
-
Cell type-specific gene expression differences in complex tissues. Nat Methods. 2010 Apr; 7(4):287-9.
Shen-Orr SS, Tibshirani R, Khatri P, Bodian DL, Staedtler F, Perry NM, Hastie T, Sarwal MM, Davis MM, Butte AJ. PMID: 20208531; PMCID: PMC3699332.
View in:
PubMed Mentions:
271 Fields:
Translation:
HumansAnimals
-
Network-based elucidation of human disease similarities reveals common functional modules enriched for pluripotent drug targets. PLoS Comput Biol. 2010 Feb 05; 6(2):e1000662.
Suthram S, Dudley JT, Chiang AP, Chen R, Hastie TJ, Butte AJ. PMID: 20140234; PMCID: PMC2816673.
View in:
PubMed Mentions:
151 Fields:
Translation:
Humans
-
Identification of complex metabolic states in critically injured patients using bioinformatic cluster analysis. Crit Care. 2010; 14(1):R10.
Cohen MJ, Grossman AD, Morabito D, Knudson MM, Butte AJ, Manley GT. PMID: 20122274; PMCID: PMC2875524.
View in:
PubMed Mentions:
41 Fields:
Translation:
Humans
-
Antibodies specifically target AML antigen NuSAP1 after allogeneic bone marrow transplantation. Blood. 2010 Mar 11; 115(10):2077-87.
Wadia PP, Coram M, Armstrong RJ, Mindrinos M, Butte AJ, Miklos DB. PMID: 20053754; PMCID: PMC2837325.
View in:
PubMed Mentions:
22 Fields:
Translation:
Humans
-
Autoimmune disease classification by inverse association with SNP alleles. PLoS Genet. 2009 Dec; 5(12):e1000792.
Sirota M, Schaub MA, Batzoglou S, Robinson WH, Butte AJ. PMID: 20041220; PMCID: PMC2791168.
View in:
PubMed Mentions:
93 Fields:
Translation:
Humans
-
A quick guide for developing effective bioinformatics programming skills. PLoS Comput Biol. 2009 Dec; 5(12):e1000589.
Dudley JT, Butte AJ. PMID: 20041221; PMCID: PMC2791169.
View in:
PubMed Mentions:
15 Fields:
-
Validating pathophysiological models of aging using clinical electronic medical records. J Biomed Inform. 2010 Jun; 43(3):358-64.
Chen DP, Morgan AA, Butte AJ. PMID: 19958842; PMCID: PMC2878870.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Dynamism in gene expression across multiple studies. Physiol Genomics. 2010 Feb 04; 40(3):128-40.
Morgan AA, Dudley JT, Deshpande T, Butte AJ. PMID: 19920211; PMCID: PMC2825768.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimals
-
FoxO3 regulates neural stem cell homeostasis. Cell Stem Cell. 2009 Nov 06; 5(5):527-39.
Renault VM, Rafalski VA, Morgan AA, Salih DA, Brett JO, Webb AE, Villeda SA, Thekkat PU, Guillerey C, Denko NC, Palmer TD, Butte AJ, Brunet A. PMID: 19896443; PMCID: PMC2775802.
View in:
PubMed Mentions:
316 Fields:
Translation:
AnimalsCells
-
Protein microarrays identify antibodies to protein kinase Czeta that are associated with a greater risk of allograft loss in pediatric renal transplant recipients. Kidney Int. 2009 Dec; 76(12):1277-83.
Sutherland SM, Li L, Sigdel TK, Wadia PP, Miklos DB, Butte AJ, Sarwal MM. PMID: 19812540; PMCID: PMC4464694.
View in:
PubMed Mentions:
34 Fields:
Translation:
Humans
-
Relationship of differential gene expression profiles in CD34+ myelodysplastic syndrome marrow cells to disease subtype and progression. Blood. 2009 Nov 26; 114(23):4847-58.
Sridhar K, Ross DT, Tibshirani R, Butte AJ, Greenberg PL. PMID: 19801443; PMCID: PMC2786292.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansCells
-
Infection in the intensive care unit alters physiological networks. BMC Bioinformatics. 2009 Sep 17; 10 Suppl 9:S4.
Grossman AD, Cohen MJ, Manley GT, Butte AJ. PMID: 19761574; PMCID: PMC2745691.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Disease signatures are robust across tissues and experiments. Mol Syst Biol. 2009; 5:307.
Dudley JT, Tibshirani R, Deshpande T, Butte AJ. PMID: 19756046; PMCID: PMC2758720.
View in:
PubMed Mentions:
63 Fields:
Translation:
Humans
-
Wiskott-Aldrich syndrome protein is an effector of Kit signaling. Blood. 2009 Oct 01; 114(14):2900-8.
Mani M, Venkatasubrahmanyam S, Sanyal M, Levy S, Butte A, Weinberg K, Jahn T. PMID: 19643989; PMCID: PMC2756200.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
-
Systematic evaluation of drug-disease relationships to identify leads for novel drug uses. Clin Pharmacol Ther. 2009 Nov; 86(5):507-10.
Chiang AP, Butte AJ. PMID: 19571805; PMCID: PMC2836384.
View in:
PubMed Mentions:
90 Fields:
Translation:
Humans
-
Translational bioinformatics applications in genome medicine. Genome Med. 2009 Jun 29; 1(6):64.
Butte AJ. PMID: 19566916; PMCID: PMC2703873.
View in:
PubMed Mentions:
8 Fields:
-
A Classifier-based approach to identify genetic similarities between diseases. Bioinformatics. 2009 Jun 15; 25(12):i21-9.
Schaub MA, Kaplow IM, Sirota M, Do CB, Butte AJ, Batzoglou S. PMID: 19477990; PMCID: PMC2687980.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
C3 polymorphisms and outcomes of renal allografts. N Engl J Med. 2009 Jun 04; 360(23):2478; author reply 2478-9.
Naesens M, Butte AJ, Sarwal MM. PMID: 19504761.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
-
MicroRNA profiling of human-induced pluripotent stem cells. Stem Cells Dev. 2009 Jun; 18(5):749-58.
Wilson KD, Venkatasubrahmanyam S, Jia F, Sun N, Butte AJ, Wu JC. PMID: 19284351; PMCID: PMC3135181.
View in:
PubMed Mentions:
113 Fields:
Translation:
HumansCells
-
Expression of complement components differs between kidney allografts from living and deceased donors. J Am Soc Nephrol. 2009 Aug; 20(8):1839-51.
Naesens M, Li L, Ying L, Sansanwal P, Sigdel TK, Hsieh SC, Kambham N, Lerut E, Salvatierra O, Butte AJ, Sarwal MM. PMID: 19443638; PMCID: PMC2723986.
View in:
PubMed Mentions:
49 Fields:
Translation:
Humans
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Identifying compartment-specific non-HLA targets after renal transplantation by integrating transcriptome and "antibodyome" measures. Proc Natl Acad Sci U S A. 2009 Mar 17; 106(11):4148-53.
Li L, Wadia P, Chen R, Kambham N, Naesens M, Sigdel TK, Miklos DB, Sarwal MM, Butte AJ. PMID: 19251643; PMCID: PMC2657434.
View in:
PubMed Mentions:
52 Fields:
Translation:
Humans
-
The "etiome": identification and clustering of human disease etiological factors. BMC Bioinformatics. 2009 Feb 05; 10 Suppl 2:S14.
Liu YI, Wise PH, Butte AJ. PMID: 19208189; PMCID: PMC2646245.
View in:
PubMed Mentions:
27 Fields:
Translation:
Humans
-
Ontology-driven indexing of public datasets for translational bioinformatics. BMC Bioinformatics. 2009 Feb 05; 10 Suppl 2:S1.
Shah NH, Jonquet C, Chiang AP, Butte AJ, Chen R, Musen MA. PMID: 19208184; PMCID: PMC2646250.
View in:
PubMed Mentions:
53 Fields:
-
Selected proceedings of the First Summit on Translational Bioinformatics 2008. BMC Bioinformatics. 2009 Feb 05; 10 Suppl 2:I1.
Butte AJ, Sarkar IN, Ramoni M, Lussier Y, Troyanskaya O. PMID: 19208183; PMCID: PMC2646246.
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PubMed Mentions: Fields:
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Data-driven methods to discover molecular determinants of serious adverse drug events. Clin Pharmacol Ther. 2009 Mar; 85(3):259-68.
Chiang AP, Butte AJ. PMID: 19177064; PMCID: PMC2726746.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimals
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Identification of discriminating biomarkers for human disease using integrative network biology. Pac Symp Biocomput. 2009; 27-38.
Dudley JT, Butte AJ. PMID: 19209693; PMCID: PMC2749008.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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Towards a cytokine-cell interaction knowledgebase of the adaptive immune system. Pac Symp Biocomput. 2009; 439-50.
Shen-Orr SS, Goldberger O, Garten Y, Rosenberg-Hasson Y, Lovelace PA, Hirschberg DL, Altman RB, Davis MM, Butte AJ. PMID: 19209721; PMCID: PMC2709757.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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GeneChaser: identifying all biological and clinical conditions in which genes of interest are differentially expressed. BMC Bioinformatics. 2008 Dec 18; 9:548.
Chen R, Mallelwar R, Thosar A, Venkatasubrahmanyam S, Butte AJ. PMID: 19094235; PMCID: PMC2629779.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Report on EU-USA workshop: how systems biology can advance cancer research (27 October 2008). Mol Oncol. 2009 Feb; 3(1):9-17.
Aebersold R, Auffray C, Baney E, Barillot E, Brazma A, Brett C, Brunak S, Butte A, Califano A, Celis J, Cufer T, Ferrell J, Galas D, Gallahan D, Gatenby R, Goldbeter A, Hace N, Henney A, Hood L, Iyengar R, Jackson V, Kallioniemi O, Klingmüller U, Kolar P, Kolch W, Kyriakopoulou C, Laplace F, Lehrach H, Marcus F, Matrisian L, Nolan G, Pelkmans L, Potti A, Sander C, Seljak M, Singer D, Sorger P, Stunnenberg H, Superti-Furga G, Uhlen M, Vidal M, Weinstein J, Wigle D, Williams M, Wolkenhauer O, Zhivotovsky B, Zinovyev A, Zupan B. PMID: 19383362; PMCID: PMC2930781.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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FitSNPs: highly differentially expressed genes are more likely to have variants associated with disease. Genome Biol. 2008; 9(12):R170.
Chen R, Morgan AA, Dudley J, Deshpande T, Li L, Kodama K, Chiang AP, Butte AJ. PMID: 19061490; PMCID: PMC2646274.
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PubMed Mentions:
42 Fields:
Translation:
Humans
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Expression-based Pathway Signature Analysis (EPSA): mining publicly available microarray data for insight into human disease. BMC Med Genomics. 2008 Oct 20; 1:51.
Tenenbaum JD, Walker MG, Utz PJ, Butte AJ. PMID: 18937865; PMCID: PMC2588448.
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PubMed Mentions:
8 Fields:
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Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family. Cell Stem Cell. 2008 Oct 09; 3(4):416-28.
Viatour P, Somervaille TC, Venkatasubrahmanyam S, Kogan S, McLaughlin ME, Weissman IL, Butte AJ, Passegué E, Sage J. PMID: 18940733; PMCID: PMC2646421.
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PubMed Mentions:
99 Fields:
Translation:
AnimalsCells
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Tissue- and age-specific changes in gene expression during disease induction and progression in NOD mice. Clin Immunol. 2008 Nov; 129(2):195-201.
Kodama K, Butte AJ, Creusot RJ, Su L, Sheng D, Hartnett M, Iwai H, Soares LR, Fathman CG. PMID: 18801706; PMCID: PMC2592195.
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PubMed Mentions:
34 Fields:
Translation:
Animals
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Translational bioinformatics: coming of age. J Am Med Inform Assoc. 2008 Nov-Dec; 15(6):709-14.
Butte AJ. PMID: 18755990; PMCID: PMC2585538.
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PubMed Mentions:
49 Fields:
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Use of Bayesian networks to probabilistically model and improve the likelihood of validation of microarray findings by RT-PCR. J Biomed Inform. 2009 Apr; 42(2):287-95.
English SB, Shih SC, Ramoni MF, Smith LE, Butte AJ. PMID: 18790084; PMCID: PMC3962641.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Medicine. The ultimate model organism. Science. 2008 Apr 18; 320(5874):325-7.
Butte AJ. PMID: 18420921; PMCID: PMC2749009.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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Novel integration of hospital electronic medical records and gene expression measurements to identify genetic markers of maturation. Pac Symp Biocomput. 2008; 243-54.
Chen DP, Weber SC, Constantinou PS, Ferris TA, Lowe HJ, Butte AJ. PMID: 18229690; PMCID: PMC2716394.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Enabling integrative genomic analysis of high-impact human diseases through text mining. Pac Symp Biocomput. 2008; 580-91.
Dudley J, Butte AJ. PMID: 18229717; PMCID: PMC2735266.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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AILUN: reannotating gene expression data automatically. Nat Methods. 2007 Nov; 4(11):879.
Chen R, Li L, Butte AJ. PMID: 17971777; PMCID: PMC2716375.
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PubMed Mentions:
67 Fields:
Translation:
HumansAnimals
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Methodologies for extracting functional pharmacogenomic experiments from international repository. AMIA Annu Symp Proc. 2007 Oct 11; 463-7.
Lin YA, Chiang A, Lin R, Yao P, Chen R, Butte AJ. PMID: 18693879; PMCID: PMC2655846.
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PubMed Mentions:
2 Fields:
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Clinical arrays of laboratory measures, or "clinarrays", built from an electronic health record enable disease subtyping by severity. AMIA Annu Symp Proc. 2007 Oct 11; 115-9.
Chen DP, Weber SC, Constantinou PS, Ferris TA, Lowe HJ, Butte AJ. PMID: 18693809; PMCID: PMC2655832.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Evaluation and integration of 49 genome-wide experiments and the prediction of previously unknown obesity-related genes. Bioinformatics. 2007 Nov 01; 23(21):2910-7.
English SB, Butte AJ. PMID: 17921495; PMCID: PMC2839901.
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PubMed Mentions:
31 Fields:
Translation:
Humans
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Multiplexed protein array platforms for analysis of autoimmune diseases. Annu Rev Immunol. 2006; 24:391-418.
Balboni I, Chan SM, Kattah M, Tenenbaum JD, Butte AJ, Utz PJ. PMID: 16551254.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Creation and implications of a phenome-genome network. Nat Biotechnol. 2006 Jan; 24(1):55-62.
Butte AJ, Kohane IS. PMID: 16404398; PMCID: PMC2716377.
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PubMed Mentions:
100 Fields:
Translation:
AnimalsCells
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Finding disease-related genomic experiments within an international repository: first steps in translational bioinformatics. AMIA Annu Symp Proc. 2006; 106-10.
Butte AJ, Chen R. PMID: 17238312; PMCID: PMC1839582.
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PubMed Mentions:
30 Fields:
Translation:
Humans
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Genome-wide analysis of host responses to the Pseudomonas aeruginosa type III secretion system yields synergistic effects. Cell Microbiol. 2005 Nov; 7(11):1635-46.
Ichikawa JK, English SB, Wolfgang MC, Jackson R, Butte AJ, Lory S. PMID: 16207250.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Systematic survey reveals general applicability of "guilt-by-association" within gene coexpression networks. BMC Bioinformatics. 2005 Sep 14; 6:227.
Wolfe CJ, Kohane IS, Butte AJ. PMID: 16162296; PMCID: PMC1239911.
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PubMed Mentions:
186 Fields:
Translation:
HumansAnimals
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Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin. Nat Cell Biol. 2005 Jun; 7(6):601-11.
Tseng YH, Butte AJ, Kokkotou E, Yechoor VK, Taniguchi CM, Kriauciunas KM, Cypess AM, Niinobe M, Yoshikawa K, Patti ME, Kahn CR. PMID: 15895078.
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PubMed Mentions:
98 Fields:
Translation:
AnimalsCells
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A computational model to define the molecular causes of type 2 diabetes mellitus. Diabetes Technol Ther. 2005 Apr; 7(2):323-36.
Pollard J, Butte AJ, Hoberman S, Joshi M, Levy J, Pappo J. PMID: 15857235.
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PubMed Mentions:
22 Fields:
Translation:
HumansCells
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Genome-scale expression profiling of Hutchinson-Gilford progeria syndrome reveals widespread transcriptional misregulation leading to mesodermal/mesenchymal defects and accelerated atherosclerosis. Aging Cell. 2004 Aug; 3(4):235-43.
Csoka AB, English SB, Simkevich CP, Ginzinger DG, Butte AJ, Schatten GP, Rothman FG, Sedivy JM. PMID: 15268757.
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PubMed Mentions:
91 Fields:
Translation:
HumansCells
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Conserved mechanisms across development and tumorigenesis revealed by a mouse development perspective of human cancers. Genes Dev. 2004 Mar 15; 18(6):629-40.
Kho AT, Zhao Q, Cai Z, Butte AJ, Kim JY, Pomeroy SL, Rowitch DH, Kohane IS. PMID: 15075291; PMCID: PMC387239.
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PubMed Mentions:
87 Fields:
Translation:
HumansAnimalsCells
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Quantifying the relationship between co-expression, co-regulation and gene function. BMC Bioinformatics. 2004 Feb 25; 5:18.
Allocco DJ, Kohane IS, Butte AJ. PMID: 15053845; PMCID: PMC375525.
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PubMed Mentions:
157 Fields:
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Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1. Proc Natl Acad Sci U S A. 2003 Jul 08; 100(14):8466-71.
Patti ME, Butte AJ, Crunkhorn S, Cusi K, Berria R, Kashyap S, Miyazaki Y, Kohane I, Costello M, Saccone R, Landaker EJ, Goldfine AB, Mun E, DeFronzo R, Finlayson J, Kahn CR, Mandarino LJ. PMID: 12832613; PMCID: PMC166252.
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PubMed Mentions:
813 Fields:
Translation:
HumansCells
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Reproducibility of gene expression across generations of Affymetrix microarrays. BMC Bioinformatics. 2003 Jun 25; 4:27.
Nimgaonkar A, Sanoudou D, Butte AJ, Haslett JN, Kunkel LM, Beggs AH, Kohane IS. PMID: 12823866; PMCID: PMC165600.
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PubMed Mentions:
28 Fields:
Translation:
Humans
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PGAGENE: integrating quantitative gene-specific results from the NHLBI programs for genomic applications. Bioinformatics. 2003 Apr 12; 19(6):778-9.
Lee K, Kohane IS, Butte AJ. PMID: 12691993.
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PubMed Mentions:
1 Fields:
Translation:
Cells
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Computerized recruiting for clinical trials in real time. Ann Emerg Med. 2003 Feb; 41(2):242-6.
Weiner DL, Butte AJ, Hibberd PL, Fleisher GR. PMID: 12548275.
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PubMed Mentions:
29 Fields:
Translation:
Humans
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Comparing expression profiles of genes with similar promoter regions. Bioinformatics. 2002 Dec; 18(12):1576-84.
Park PJ, Butte AJ, Kohane IS. PMID: 12490441.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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The use and analysis of microarray data. Nat Rev Drug Discov. 2002 Dec; 1(12):951-60.
Butte A. PMID: 12461517.
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PubMed Mentions:
112 Fields:
Translation:
HumansAnimals
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Analysis of matched mRNA measurements from two different microarray technologies. Bioinformatics. 2002 Mar; 18(3):405-12.
Kuo WP, Jenssen TK, Butte AJ, Ohno-Machado L, Kohane IS. PMID: 11934739.
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PubMed Mentions:
155 Fields:
Translation:
HumansCells
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Further defining housekeeping, or "maintenance," genes Focus on "A compendium of gene expression in normal human tissues". Physiol Genomics. 2001 Dec 21; 7(2):95-6.
Butte AJ, Dzau VJ, Glueck SB. PMID: 11773595.
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PubMed Mentions:
75 Fields:
Translation:
Humans
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Comparing the similarity of time-series gene expression using signal processing metrics. J Biomed Inform. 2001 Dec; 34(6):396-405.
Butte AJ, Bao L, Reis BY, Watkins TW, Kohane IS. PMID: 12198759.
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PubMed Mentions:
8 Fields:
Translation:
Animals
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Strict interpretation of vaccination guidelines with computerized algorithms and improper timing of administered doses. Pediatr Infect Dis J. 2001 Jun; 20(6):561-5.
Butte AJ, Shaw JS, Bernstein H. PMID: 11419495.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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The personal internetworked notary and guardian. Int J Med Inform. 2001 Jun; 62(1):27-40.
Riva A, Mandl KD, Oh DH, Nigrin DJ, Butte A, Szolovits P, Kohane IS. PMID: 11340004.
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PubMed Mentions:
13 Fields:
Translation:
HumansPHPublic Health
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Challenges in bioinformatics: infrastructure, models and analytics. Trends Biotechnol. 2001 May; 19(5):159-60.
Butte AJ. PMID: 11403022.
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PubMed Mentions:
4 Fields:
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Extracting knowledge from dynamics in gene expression. J Biomed Inform. 2001 Feb; 34(1):15-27.
Reis BY, Butte AS, Kohane IS. PMID: 11376539.
View in:
PubMed Mentions:
3 Fields:
Translation:
Animals
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Determining significant fold differences in gene expression analysis. Pac Symp Biocomput. 2001; 6-17.
Butte AJ, Ye J, Häring HU, Stumvoll M, White MF, Kohane IS. PMID: 11262977.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks. Proc Natl Acad Sci U S A. 2000 Oct 24; 97(22):12182-6.
Butte AJ, Tamayo P, Slonim D, Golub TR, Kohane IS. PMID: 11027309; PMCID: PMC17315.
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PubMed Mentions:
190 Fields:
Translation:
HumansCells
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Severe hypothyroidism caused by type 3 iodothyronine deiodinase in infantile hemangiomas. N Engl J Med. 2000 Jul 20; 343(3):185-9.
Huang SA, Tu HM, Harney JW, Venihaki M, Butte AJ, Kozakewich HP, Fishman SJ, Larsen PR. PMID: 10900278.
View in:
PubMed Mentions:
101 Fields:
Translation:
Humans
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Mutual information relevance networks: functional genomic clustering using pairwise entropy measurements. Pac Symp Biocomput. 2000; 418-29.
Butte AJ, Kohane IS. PMID: 10902190.
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PubMed Mentions:
325 Fields:
Translation:
HumansAnimals
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Enrolling patients into clinical trials faster using RealTime Recuiting. Proc AMIA Symp. 2000; 111-5.
Butte AJ, Weinstein DA, Kohane IS. PMID: 11079855; PMCID: PMC2244056.
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PubMed Mentions:
34 Fields:
Translation:
Humans
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Unsupervised knowledge discovery in medical databases using relevance networks. Proc AMIA Symp. 1999; 711-5.
Butte AJ, Kohane IS. PMID: 10566452; PMCID: PMC2232846.
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PubMed Mentions:
32 Fields:
Translation:
Humans
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Insulin receptor substrate 1 mediates the stimulatory effect of insulin on GLUT4 translocation in transfected rat adipose cells. J Biol Chem. 1994 Nov 11; 269(45):27920-4.
Quon MJ, Butte AJ, Zarnowski MJ, Sesti G, Cushman SW, Taylor SI. PMID: 7525563.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCells
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Insulin signal transduction pathways. Trends Endocrinol Metab. 1994 Nov; 5(9):369-76.
Quon MJ, Butte AJ, Taylor SI. PMID: 18407232.
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PubMed Mentions:
4 Fields:
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Tyrosine kinase-deficient mutant human insulin receptors (Met1153-->Ile) overexpressed in transfected rat adipose cells fail to mediate translocation of epitope-tagged GLUT4. Proc Natl Acad Sci U S A. 1994 Jun 07; 91(12):5587-91.
Quon MJ, Guerre-Millo M, Zarnowski MJ, Butte AJ, Em M, Cushman SW, Taylor SI. PMID: 8202531; PMCID: PMC44041.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Derivation of a scale-independent parameter which characterizes genetic sequence comparisons. Comput Biomed Res. 1993 Dec; 26(6):517-40.
DePetrillo PB, Butte AJ. PMID: 8112054.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells