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Audrey Hendley, PhD

Title(s)Postdoctoral Scholar, Diabetes Center
SchoolSchool of Medicine
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    Collapse Biography 
    Collapse Education and Training
    Johns Hopkins Univeristy School of MedicinePh.D. Human Genetics and Molecular Biology2016McKusick/Nathans Institute of Genetic Medicine
    University of South Carolina AikenB.S. Biology (Major), Chemistry (Minor)2009Department of Biology and Geology
    Collapse Awards and Honors
    University of California San Francisco2017  - 2019F32 Individual Postdoctoral Fellowship (NRSA)
    University of California San Francisco2016  - 2017Seed Grant Recipient, Hirshberg Foundation for Pancreatic Cancer Research
    University of California San Francisco2016  - 2017T32 Institutional National Research Service Award (NRSA)
    Johns Hopkins University School of Medicine2009  - 2011T32 Institutional National Research Service Award (NRSA)
    University of South Carolina Aiken2009Outstanding Senior Student
    University of South Carolina Aiken2009Biology Student of the Year
    University of South Carolina2008Magellan Research Scholarship

    Collapse Research 
    Collapse Research Activities and Funding
    Examination of ceramide signaling in the crosstalk between pancreatic cancer cells and the tumor microenvironment
    NIH/NCI F32CA221114Dec 1, 2017 - Nov 30, 2020
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Hendley AM, Wang YJ, Polireddy K, Alsina J, Ahmed I, Lafaro KJ, Zhang H, Roy N, Savidge SG, Cao Y, Hebrok M, Maitra A, Reynolds AB, Goggins M, Younes M, Iacobuzio-Donahue CA, Leach SD, Bailey JM. p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia. Cancer Res. 2016 06 01; 76(11):3351-63. PMID: 27032419.
      View in: PubMed
    2. Choi E, Hendley AM, Bailey JM, Leach SD, Goldenring JR. Expression of Activated Ras in Gastric Chief Cells of Mice Leads to the Full Spectrum of Metaplastic Lineage Transitions. Gastroenterology. 2016 Apr; 150(4):918-30.e13. PMID: 26677984.
      View in: PubMed
    3. Bailey JM, Hendley AM, Lafaro KJ, Pruski MA, Jones NC, Alsina J, Younes M, Maitra A, McAllister F, Iacobuzio-Donahue CA, Leach SD. p53 mutations cooperate with oncogenic Kras to promote adenocarcinoma from pancreatic ductal cells. Oncogene. 2016 08 11; 35(32):4282-8. PMID: 26592447.
      View in: PubMed
    4. Bailey JM, Hendley AM, Maitra A. New insights into plasticity of pancreatic cancer: cancer to acinar cell reprogramming by the basic helix-loop-helix transcription factor E47. Pancreas. 2015 Jul; 44(5):683-5. PMID: 26061556.
      View in: PubMed
    5. Audrey M. Hendley, Jennifer M. Bailey. Stem Cells and Pancreatic Cancer. Principles of Stem Cell Biology and Cancer. 2015 May 18; 213-229.
      View in: Publisher Site
    6. Eunyoung Choi, Audrey M. Hendley, Jennifer M. Bailey, Steven Leach, James R. Goldenring. 11 Inhibition of KRAS Activation Ameliorates Pre-Cancerous Metaplastic Conversion in the Mouse Stomach. Gastroenterology. 2015 Apr 1; 148(4):s-5.
      View in: Publisher Site
    7. Jennifer M Bailey, Audrey M. Hendley, Conover Talbot, Christine A Iacobuzio-Donahue, Steven Leach. 800f Even Pancreatic Duct Cells Can Serve As a Cell of Origin for Pancreatic Cancer: Requirement for Cooperating Genetic Lesions. Gastroenterology. 2015 Apr 1; 148(4):s-1192-s-1193.
      View in: Publisher Site
    8. Hendley AM, Bailey, JM.Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics. Regad T, Sayers TJ, Rees RC, editors. Chapter 11, Stem Cells and Pancreatic Cancer. 2015; 213-229.
    9. Hendley AM, Provost E, Bailey JM, Wang YJ, Cleveland MH, Blake D, Bittman RW, Roeser JC, Maitra A, Reynolds AB, Leach SD. p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas. Dev Biol. 2015 Mar 01; 399(1):41-53. PMID: 25523391.
      View in: PubMed
    10. Wang YJ, McAllister F, Bailey JM, Scott SG, Hendley AM, Leach SD, Ghosh B. Dicer is required for maintenance of adult pancreatic acinar cell identity and plays a role in Kras-driven pancreatic neoplasia. PLoS One. 2014; 9(11):e113127. PMID: 25405615.
      View in: PubMed
    11. Eunyoung Choi, Audrey M. Hendley, Christine Petersen, Victoria G. Weis, Steven D. Leach, James R. Goldenring. 266 Active Kras Leads to Rapid Transdifferentiation of Gastric Chief Cells Into Metaplasia With Progression to Dysplasia and Invasive Cancer. Gastroenterology. 2014 May 1; 146(5):s-64.
      View in: Publisher Site
    12. Audrey M. Hendley, Elayne Provost, Danielle Blake, Jeffrey Roeser, Albert Reynolds, Steven Leach. Loss of p120ctn in the pancreas results in expansion of ductal epithelium and loss of acinar cells. Developmental Biology. 2011 Aug 1; 356(1):169.
      View in: Publisher Site
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