Bettina Van Lengerich, PhD

TitlePostdoctoral Scholar
SchoolUCSF School of Medicine
DepartmentCardiovascular Research Inst
Address555 Mission Bay Blvd South
San Francisco CA 94158
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. van Lengerich B, Agnew C, Puchner EM, Huang B, Jura N. EGF and NRG induce phosphorylation of HER3/ERBB3 by EGFR using distinct oligomeric mechanisms. Proc Natl Acad Sci U S A. 2017 Apr 04; 114(14):E2836-E2845. PMID: 28320942.
      View in: PubMed
    2. Johnson MG, Liu JJ, Li AR, van Lengerich B, Wang S, Medina JC, Collins TL, Danao J, Seitz L, Willee A, D'Souza W, Budelsky AL, Fan PW, Wong SG. Solving time-dependent CYP3A4 inhibition for a series of indole-phenylacetic acid dual antagonists of the PGD(2) receptors CRTH2 and DP. Bioorg Med Chem Lett. 2014 Jul 1; 24(13):2877-80. PMID: 24825301.
      View in: PubMed
    3. van Lengerich B, Rawle RJ, Bendix PM, Boxer SG. Individual vesicle fusion events mediated by lipid-anchored DNA. Biophys J. 2013 Jul 16; 105(2):409-19. PMID: 23870262; PMCID: PMC3714935.
    4. Liu JJ, Wang Y, Johnson MG, Li AR, Shen W, Wang X, Su Y, Brown M, Van Lengerich B, Rickel E, Martin T, Budelsky A, Seitz L, Danao J, Tang HL, Collins T, Medina JC. Optimization of phenylacetic acid derivatives for balanced CRTH2 and DP dual antagonists. Bioorg Med Chem Lett. 2012 Feb 15; 22(4):1686-9. PMID: 22264478.
      View in: PubMed
    5. Rawle RJ, van Lengerich B, Chung M, Bendix PM, Boxer SG. Vesicle fusion observed by content transfer across a tethered lipid bilayer. Biophys J. 2011 Oct 19; 101(8):L37-9. PMID: 22004762; PMCID: PMC3192961.
    6. Liu J, Li AR, Wang Y, Johnson MG, Su Y, Shen W, Wang X, Lively S, Brown M, Lai S, Gonzalez Lopez De Turiso F, Xu Q, Van Lengerich B, Schmitt M, Fu Z, Sun Y, Lawlis S, Seitz L, Danao J, Wait J, Ye Q, Tang HL, Grillo M, Collins TL, Sullivan TJ, Medina JC. Discovery of AMG 853, a CRTH2 and DP Dual Antagonist. ACS Med Chem Lett. 2011 May 12; 2(5):326-30. PMID: 24900313; PMCID: PMC4018074.
    7. van Lengerich B, Rawle RJ, Boxer SG. Covalent attachment of lipid vesicles to a fluid-supported bilayer allows observation of DNA-mediated vesicle interactions. Langmuir. 2010 Jun 1; 26(11):8666-72. PMID: 20180548; PMCID: PMC2877162.
    8. Chan YH, van Lengerich B, Boxer SG. Effects of linker sequences on vesicle fusion mediated by lipid-anchored DNA oligonucleotides. Proc Natl Acad Sci U S A. 2009 Jan 27; 106(4):979-84. PMID: 19164559; PMCID: PMC2633564.
    9. Tonn GR, Wong SG, Wong SC, Johnson MG, Ma J, Cho R, Floren LC, Kersey K, Berry K, Marcus AP, Wang X, Van Lengerich B, Medina JC, Pearson PG, Wong BK. An inhibitory metabolite leads to dose- and time-dependent pharmacokinetics of (R)-N-{1-[3-(4-ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in human subjects after multiple dosing. Drug Metab Dispos. 2009 Mar; 37(3):502-13. PMID: 19088267.
      View in: PubMed
    10. Chan YH, van Lengerich B, Boxer SG. Lipid-anchored DNA mediates vesicle fusion as observed by lipid and content mixing. Biointerphases. 2008 Jun; 3(2):FA17. PMID: 20408664.
      View in: PubMed
    11. Phillips ST, Piersanti G, RĂ¼th M, Gubernator N, van Lengerich B, Bartlett PA. Facile synthesis of @-tide beta-strand peptidomimetics: improved assembly in solution and on solid phase. Org Lett. 2004 Nov 25; 6(24):4483-5. PMID: 15548056.
      View in: PubMed
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